EP1397342A1 - Verfahren zur herstellung von sertralinzwischenprodukten - Google Patents

Verfahren zur herstellung von sertralinzwischenprodukten

Info

Publication number
EP1397342A1
EP1397342A1 EP02727626A EP02727626A EP1397342A1 EP 1397342 A1 EP1397342 A1 EP 1397342A1 EP 02727626 A EP02727626 A EP 02727626A EP 02727626 A EP02727626 A EP 02727626A EP 1397342 A1 EP1397342 A1 EP 1397342A1
Authority
EP
European Patent Office
Prior art keywords
dichlorophenyl
dihydro
sertraline
cis
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02727626A
Other languages
English (en)
French (fr)
Inventor
Ilpo Laitinen
Pekka PIETIKÄINEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fermion Oy
Original Assignee
Orion Yhtyma Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20011146A external-priority patent/FI20011146A0/fi
Application filed by Orion Yhtyma Fermion Oy filed Critical Orion Yhtyma Fermion Oy
Publication of EP1397342A1 publication Critical patent/EP1397342A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/86—Separation
    • C07C209/88—Separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP02727626A 2001-05-31 2002-05-30 Verfahren zur herstellung von sertralinzwischenprodukten Withdrawn EP1397342A1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29426601P 2001-05-31 2001-05-31
FI20011146A FI20011146A0 (fi) 2001-05-31 2001-05-31 Uusi valmistusmenetelmä
US294266P 2001-05-31
FI20011146 2001-05-31
PCT/FI2002/000466 WO2002096860A1 (en) 2001-05-31 2002-05-30 Process for preparing sertraline intermediates

Publications (1)

Publication Number Publication Date
EP1397342A1 true EP1397342A1 (de) 2004-03-17

Family

ID=26161179

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02727626A Withdrawn EP1397342A1 (de) 2001-05-31 2002-05-30 Verfahren zur herstellung von sertralinzwischenprodukten

Country Status (3)

Country Link
EP (1) EP1397342A1 (de)
CA (1) CA2448300A1 (de)
WO (1) WO2002096860A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200808115T1 (tr) * 2006-04-28 2009-03-23 Sandoz Ag 4(S,R)-(3,4-diklorofenil)-3,4-dihidro-l(2H)-naftalin-l-ilid n]metilamin'ın Hazırlanması için Proses.@

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
IN191358B (de) * 1998-01-16 2003-11-29 Pfizer Prod Inc
YU32700A (sh) * 1999-06-09 2002-03-18 Pfizer Products Inc. Postupak za dobijanje sertralina iz hiralnog tetralona
IN185109B (de) * 1999-09-01 2000-11-18 Torrent Pharmaceuticals Ltd
WO2001036377A1 (en) * 1999-11-16 2001-05-25 Ciba Specialty Chemicals Holding Inc. Process for the preparation of ketimines
CA2388816A1 (en) * 1999-11-16 2001-05-25 Ciba Specialty Chemicals Holding Inc. Process for the preparation of ketimines
SK8872002A3 (en) * 1999-12-21 2002-12-03 Teva Pharma Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO02096860A1 *

Also Published As

Publication number Publication date
CA2448300A1 (en) 2002-12-05
WO2002096860A1 (en) 2002-12-05

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20031204

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20061201