EP1383457A1 - Distributeur de medicament - Google Patents

Distributeur de medicament

Info

Publication number
EP1383457A1
EP1383457A1 EP02727472A EP02727472A EP1383457A1 EP 1383457 A1 EP1383457 A1 EP 1383457A1 EP 02727472 A EP02727472 A EP 02727472A EP 02727472 A EP02727472 A EP 02727472A EP 1383457 A1 EP1383457 A1 EP 1383457A1
Authority
EP
European Patent Office
Prior art keywords
container body
medicament
medicament dispenser
dispenser according
lid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02727472A
Other languages
German (de)
English (en)
Inventor
David Henry Wykes
Paul Stephen Sankar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of EP1383457A1 publication Critical patent/EP1383457A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0046—Cups, bottles or bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2814—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
    • B65D51/2821—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being a blister, a capsule or like sealed container

Definitions

  • the present invention relates to a medicament dispenser.
  • the present invention is directed to a medicament dispenser that can be used conveniently and 5 at any desired location.
  • the invention provides a medicament dispenser comprising a container body having an opening from which to access the contents of said body, the exterior of said body having at least one pressure point for communication with a blister containing a medicament and/or a dietary supplement, such that application of pressure to the pressure point breaks the blister and so o liberates the medicament and/or dietary supplement into the interior of said container body.
  • the pressure point can in one embodiment form part of the blister and the applied pressure act such as to rupture the blister.
  • the blister has a peelable seal such that access thereto is by application of peeling pressure.
  • Other variations are envisaged comprising other known blister pack types.
  • the dispenser may be in the form of a flat-pack for assembly into a container body.
  • a consumer would have a dispenser on his/her person, or buy such a dispenser, assemble it into a container body, fill with liquid for aiding ingestion of the medicament or dietary supplement, liberate the contents of the blister pack supplied on the container body and consume the resulting mixture.
  • the container body is filled with a beverage.
  • the beverage may be selected from water, mineral water, fruit juice, a soft drink or tonic.
  • the tonic may be a high energy tonic possibly including a stimulant such as caffeine or taurine; or a soluble vitamin such as vitamin C.
  • a consumer would have a quick and convenient way of taking a medicament/dietary supplement at any time and at any place, for example, whether on public transport, in an elevator or during a business meeting.
  • the container body further comprises a removable lid.
  • the at least one pressure point is located on the removable lid.
  • the blister may comprise a single independent dose of medicament and/or dietary supplement in a single blister.
  • the blister may form part of a blister pack comprising a plurality of blisters so that the dispenser comprises a plurality of independent doses of medicament and/or dietary supplement, that is, one dose is disposed in each blister.
  • each blister in a blister pack may contain a dose of medicament and a dietary supplement such as one or more vitamins and/or caffeine and/or taurine.
  • a dietary supplement such as one or more vitamins and/or caffeine and/or taurine.
  • the medicament and/or dietary supplement may be in tablet, capsule, powder or liquid form.
  • the medicament and/or dietary supplement are in tablet form.
  • the container body has a neck member about which the removable lid fits thereover.
  • the blister may have an adhesive backing suitable for attachment to the neck of the container body.
  • the removable lid is rotatable about the neck member and container body.
  • the lid may comprise an annulus rotatable about an axis central to the lid, neck and container body, on which the at least one pressure point is located, such that the at least one pressure point is rotatable relative to the lid, the neck and the container body.
  • the consumer would be able to rotate the lid and/or annulus relative to the container body in order to align a pressure point with the next full blister.
  • the blister is on the dispenser, either as an integral part thereof or add-on feature thereto.
  • the removable lid may be securable to the container body by a clip-on, and/or snap- fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
  • the opening for access to the contents of the container body is in situ on the removable lid.
  • the access opening is removably sealable with a cover member.
  • the cover member may be securable to the lid by a clip-on, and/or snap-fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
  • the cover is attached to the lid by a flexible linkage.
  • the invention a container body for use with the medicament dispenser as described hereinabove.
  • the invention provides a kit of parts comprising a container body, a dose of medicament and a beverage in which to mix the medicament.
  • Figure 1 shows a flat pack medicament dispenser in accordance with one aspect of the invention
  • Figure 2 shows a disposable water-filled medicament dispenser in accordance with another aspect of the invention
  • FIG 3 shows a refillable medicament dispenser in accordance with yet another aspect of the invention
  • Figures 4a and 4b shows a variation of the flat pack medicament dispenser of Figure 1.
  • a flat-pack version of the dispenser 2 is illustrated in Figure 1.
  • the flat-pack is simply squeezed (in the direction of the arrows) to open out the carton material into the shape of a beverage container.
  • a pressure point 4 is located on the side of the exterior of the container.
  • a tablet of medicament housed inside a blister pack (not shown) on the other side of the pressure point, expels the tablet into the interior of the container.
  • the medicament can be consumed quickly and easily.
  • the medicament dispenser 6 illustrated in Figure 2 is a disposable unit.
  • the container body 8 is already filled with a beverage, such as mineral water 10.
  • a pressure point 12 on the exterior of the unit is linked to a single blister pack 14 housing one dose of medicament 16.
  • the blister pack 14 housing is located at a position somewhat above the normal fluid fill position of the 5 container body 8 to minimise the time of fluid immersion before consumption. Release of the medicament into the beverage by the application of pressure to the pressure point results in a single dose for consumption.
  • This unit is especially useful for people who may suffer from ailments such as colds, influenza, hayfever and so on and can be seen as an instant remedy for people with busy lives.
  • Figure 3 illustrates a refillable, reusable medicament dispenser 20.
  • an adhesive-backed blister pack 22 containing a plurality of discrete doses, one in each blister, to the dispenser and filling it with a liquid of choice the unit may be used throughout the day, for example, when regular doses of pain-killers are required.
  • the container body 24 is interchangeable in this embodiment so that different dosages and configurations can be adopted to suit the consumer.
  • the dispenser 20 comprises the container body 24 having a neck 26 for attachment of the strip of blisters 22 containing the medicament of choice.
  • a lid 28 Around and on top of o the neck is fitted a lid 28 which clips snugly onto the container body.
  • a protective cover 32 can then be removed from the top of the lid and the medicament and liquid be consumed by the user.
  • Figures 4a and 4b respectively show front and back unfolded (i.e. disassembled) views of a medicament dispenser 2 of a type similar to that shown in Figure 1. It may be appreciated that when assembled by folding and adhesively joining at respective join portions 3a, 3b and 3c a flat-pack beverage container is formed. Pressure point 4 may be clearly seen on the front of the dispenser pack as may the blister pack 5 on the other side of the pressure point 4. Access to the blister pack is by application of user pressure to the pressure point 4 to expel the medicament (e.g. in tablet form) therein into the container body.
  • the medicament e.g. in tablet form
  • Appropriate medicaments for dispensing may be selected from, for example, analgesics, e.g., codeine, dihydromorphine, ergotamine, fentanyl or morphine; anginal preparations, e.g., diltiazem; antiallergics, e.g., cromoglycate (eg s the sodium salt), ketotifen or nedocromil (eg as the sodium salt); antiinfectives e.g., cephalosporins, penicillins, streptomycin, sulphonamides, tetracyclines and pentamidine; antihistamines, e.g., methapyrilene; anti- inflammatories, e.g., beclomethasone (eg as the dipropionate ester), fluticasone (eg as the propionate ester), flunisolide, budesonide, rofleponide, mometasone
  • ⁇ 4 integrin inhibitors eg (2S)-3-[4-( ⁇ [4-(aminocarbonyl)-1- piperidinyl]carbonyl ⁇ oxy)phenyl]-2-[((2S)-4-methyl-2- ⁇ [2-(2-methylphenoxy) acetyl]amino ⁇ pentanoyljamino] propanoic acid (e.g as free acid or potassium salt), diuretics, e.g., amiloride; anticholinergics, e.g., ipratropium (eg as bromide), tiotropium, atropine or oxitropium; hormones, e.g., cortisone, hydrocortisone or prednisolone; xanthines, e.g., aminophylline, choline theophyllinate, lysine theophyllinate or theophylline; therapeutic proteins and peptides, e.g., insulin or gluca
  • the medicaments may be used in the form of salts, (e.g., as alkali metal or amine salts or as acid addition salts) or as esters (e.g., lower alkyl esters) or as solvates (e.g., hydrates) to optimise the activity and/or stability of the medicament.
  • salts e.g., as alkali metal or amine salts or as acid addition salts
  • esters e.g., lower alkyl esters
  • solvates e.g., hydrates
  • any of the parts of the dispenser may be coated with materials such as fluoropolymer materials which reduce the tendency of medicament to adhere thereto.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)

Abstract

L'invention concerne un distributeur de médicament comprenant un corps de contenant présentant une ouverture permettant d'accéder aux contenus de ce corps, l'extérieur du corps comprenant au moins un point de pression destiné à communiquer avec un emballage-coque renfermant un médicament et/ou un complément alimentaire, de manière que l'application de pression sur le point de pression rompe l'emballage-coque et libère ainsi le médicament et/ou le complément alimentaire à l'intérieur du corps de contenant.
EP02727472A 2001-04-28 2002-03-25 Distributeur de medicament Withdrawn EP1383457A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0110485A GB0110485D0 (en) 2001-04-28 2001-04-28 Medicament dispenser
GB0110485 2001-04-28
PCT/EP2002/003323 WO2002087489A1 (fr) 2001-04-28 2002-03-25 Distributeur de medicament

Publications (1)

Publication Number Publication Date
EP1383457A1 true EP1383457A1 (fr) 2004-01-28

Family

ID=9913683

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02727472A Withdrawn EP1383457A1 (fr) 2001-04-28 2002-03-25 Distributeur de medicament

Country Status (4)

Country Link
EP (1) EP1383457A1 (fr)
JP (1) JP2004528107A (fr)
GB (1) GB0110485D0 (fr)
WO (1) WO2002087489A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2278332A1 (fr) 2009-07-20 2011-01-26 Fondazione Centro San Raffaele del Monte Tabor Procédé de mesure optique de variations de la conductivité de la membrane cellulaire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1261684A (fr) * 1959-07-14 1961-05-19 Chesebrough Ponds Flacon compressible en résine synthétique
AUPO070596A0 (en) * 1996-06-27 1996-07-18 Gartner, Bradley Francis Closure cap
US6105760A (en) * 1997-10-14 2000-08-22 Mollstam; Bo Two-compartment package
EP1042187B1 (fr) * 1998-10-26 2005-01-05 Pill & Sip Limited Emballage pour comprimes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO02087489A1 *

Also Published As

Publication number Publication date
GB0110485D0 (en) 2001-06-20
JP2004528107A (ja) 2004-09-16
WO2002087489A1 (fr) 2002-11-07

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