EP1383457A1 - Medicament dispenser - Google Patents
Medicament dispenserInfo
- Publication number
- EP1383457A1 EP1383457A1 EP02727472A EP02727472A EP1383457A1 EP 1383457 A1 EP1383457 A1 EP 1383457A1 EP 02727472 A EP02727472 A EP 02727472A EP 02727472 A EP02727472 A EP 02727472A EP 1383457 A1 EP1383457 A1 EP 1383457A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container body
- medicament
- medicament dispenser
- dispenser according
- lid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title claims abstract description 71
- 235000015872 dietary supplement Nutrition 0.000 claims abstract description 16
- 235000013361 beverage Nutrition 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 230000001256 tonic effect Effects 0.000 claims description 4
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 235000015203 fruit juice Nutrition 0.000 claims description 2
- 238000011065 in-situ storage Methods 0.000 claims description 2
- 235000014214 soft drink Nutrition 0.000 claims description 2
- -1 e.g. Chemical compound 0.000 description 10
- 239000007788 liquid Substances 0.000 description 5
- 239000003826 tablet Substances 0.000 description 5
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- 229960001948 caffeine Drugs 0.000 description 2
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 229910021653 sulphate ion Inorganic materials 0.000 description 2
- 229960003080 taurine Drugs 0.000 description 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 description 1
- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 description 1
- AKNNEGZIBPJZJG-MSOLQXFVSA-N (-)-noscapine Chemical compound CN1CCC2=CC=3OCOC=3C(OC)=C2[C@@H]1[C@@H]1C2=CC=C(OC)C(OC)=C2C(=O)O1 AKNNEGZIBPJZJG-MSOLQXFVSA-N 0.000 description 1
- UBLVUWUKNHKCJJ-ZSCHJXSPSA-N (2s)-2,6-diaminohexanoic acid;1,3-dimethyl-7h-purine-2,6-dione Chemical compound NCCCC[C@H](N)C(O)=O.O=C1N(C)C(=O)N(C)C2=C1NC=N2 UBLVUWUKNHKCJJ-ZSCHJXSPSA-N 0.000 description 1
- WRRSFOZOETZUPG-FFHNEAJVSA-N (4r,4ar,7s,7ar,12bs)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol;hydrate Chemical compound O.C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC WRRSFOZOETZUPG-FFHNEAJVSA-N 0.000 description 1
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 description 1
- YREYLAVBNPACJM-UHFFFAOYSA-N 2-(tert-butylamino)-1-(2-chlorophenyl)ethanol Chemical compound CC(C)(C)NCC(O)C1=CC=CC=C1Cl YREYLAVBNPACJM-UHFFFAOYSA-N 0.000 description 1
- LSLYOANBFKQKPT-DIFFPNOSSA-N 5-[(1r)-1-hydroxy-2-[[(2r)-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]benzene-1,3-diol Chemical compound C([C@@H](C)NC[C@H](O)C=1C=C(O)C=C(O)C=1)C1=CC=C(O)C=C1 LSLYOANBFKQKPT-DIFFPNOSSA-N 0.000 description 1
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 229930003347 Atropine Natural products 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- QWOJMRHUQHTCJG-UHFFFAOYSA-N CC([CH2-])=O Chemical compound CC([CH2-])=O QWOJMRHUQHTCJG-UHFFFAOYSA-N 0.000 description 1
- 229930186147 Cephalosporin Natural products 0.000 description 1
- LUKZNWIVRBCLON-GXOBDPJESA-N Ciclesonide Chemical compound C1([C@H]2O[C@@]3([C@H](O2)C[C@@H]2[C@@]3(C[C@H](O)[C@@H]3[C@@]4(C)C=CC(=O)C=C4CC[C@H]32)C)C(=O)COC(=O)C(C)C)CCCCC1 LUKZNWIVRBCLON-GXOBDPJESA-N 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 description 1
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- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 1
- 102400000321 Glucagon Human genes 0.000 description 1
- 108060003199 Glucagon Proteins 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- HUYWAWARQUIQLE-UHFFFAOYSA-N Isoetharine Chemical compound CC(C)NC(CC)C(O)C1=CC=C(O)C(O)=C1 HUYWAWARQUIQLE-UHFFFAOYSA-N 0.000 description 1
- ZCVMWBYGMWKGHF-UHFFFAOYSA-N Ketotifene Chemical compound C1CN(C)CCC1=C1C2=CC=CC=C2CC(=O)C2=C1C=CS2 ZCVMWBYGMWKGHF-UHFFFAOYSA-N 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- VQDBNKDJNJQRDG-UHFFFAOYSA-N Pirbuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=N1 VQDBNKDJNJQRDG-UHFFFAOYSA-N 0.000 description 1
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- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
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- 229910052783 alkali metal Inorganic materials 0.000 description 1
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- 125000005907 alkyl ester group Chemical group 0.000 description 1
- AKNNEGZIBPJZJG-UHFFFAOYSA-N alpha-noscapine Natural products CN1CCC2=CC=3OCOC=3C(OC)=C2C1C1C2=CC=C(OC)C(OC)=C2C(=O)O1 AKNNEGZIBPJZJG-UHFFFAOYSA-N 0.000 description 1
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- 239000012458 free base Substances 0.000 description 1
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- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 1
- 229960004666 glucagon Drugs 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
- 229960000890 hydrocortisone Drugs 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 102000006495 integrins Human genes 0.000 description 1
- 108010044426 integrins Proteins 0.000 description 1
- OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 description 1
- 229960001888 ipratropium Drugs 0.000 description 1
- 229960001268 isoetarine Drugs 0.000 description 1
- 229960001317 isoprenaline Drugs 0.000 description 1
- 229960004958 ketotifen Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- LMOINURANNBYCM-UHFFFAOYSA-N metaproterenol Chemical compound CC(C)NCC(O)C1=CC(O)=CC(O)=C1 LMOINURANNBYCM-UHFFFAOYSA-N 0.000 description 1
- HNJJXZKZRAWDPF-UHFFFAOYSA-N methapyrilene Chemical compound C=1C=CC=NC=1N(CCN(C)C)CC1=CC=CS1 HNJJXZKZRAWDPF-UHFFFAOYSA-N 0.000 description 1
- 229960001869 methapyrilene Drugs 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229960001664 mometasone Drugs 0.000 description 1
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- PLPRGLOFPNJOTN-UHFFFAOYSA-N narcotine Natural products COc1ccc2C(OC(=O)c2c1OC)C3Cc4c(CN3C)cc5OCOc5c4OC PLPRGLOFPNJOTN-UHFFFAOYSA-N 0.000 description 1
- 229960004398 nedocromil Drugs 0.000 description 1
- RQTOOFIXOKYGAN-UHFFFAOYSA-N nedocromil Chemical compound CCN1C(C(O)=O)=CC(=O)C2=C1C(CCC)=C1OC(C(O)=O)=CC(=O)C1=C2 RQTOOFIXOKYGAN-UHFFFAOYSA-N 0.000 description 1
- 229960004708 noscapine Drugs 0.000 description 1
- 229960002657 orciprenaline Drugs 0.000 description 1
- NVOYVOBDTVTBDX-PMEUIYRNSA-N oxitropium Chemical compound CC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1 NVOYVOBDTVTBDX-PMEUIYRNSA-N 0.000 description 1
- 229960000797 oxitropium Drugs 0.000 description 1
- RLANKEDHRWMNRO-UHFFFAOYSA-M oxtriphylline Chemical compound C[N+](C)(C)CCO.O=C1N(C)C(=O)N(C)C2=C1[N-]C=N2 RLANKEDHRWMNRO-UHFFFAOYSA-M 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
- XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 description 1
- 229960004448 pentamidine Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229960001802 phenylephrine Drugs 0.000 description 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 description 1
- 229960000395 phenylpropanolamine Drugs 0.000 description 1
- DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 description 1
- 229960005414 pirbuterol Drugs 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 1
- 229960002720 reproterol Drugs 0.000 description 1
- WVLAAKXASPCBGT-UHFFFAOYSA-N reproterol Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC(O)C1=CC(O)=CC(O)=C1 WVLAAKXASPCBGT-UHFFFAOYSA-N 0.000 description 1
- 229960001457 rimiterol Drugs 0.000 description 1
- IYMMESGOJVNCKV-SKDRFNHKSA-N rimiterol Chemical compound C([C@@H]1[C@@H](O)C=2C=C(O)C(O)=CC=2)CCCN1 IYMMESGOJVNCKV-SKDRFNHKSA-N 0.000 description 1
- 229950004432 rofleponide Drugs 0.000 description 1
- IXTCZMJQGGONPY-XJAYAHQCSA-N rofleponide Chemical compound C1([C@@H](F)C2)=CC(=O)CC[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3O[C@@H](CCC)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O IXTCZMJQGGONPY-XJAYAHQCSA-N 0.000 description 1
- 229960002052 salbutamol Drugs 0.000 description 1
- 229960004017 salmeterol Drugs 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 description 1
- 229960000195 terbutaline Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 description 1
- 229940110309 tiotropium Drugs 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- 229960000859 tulobuterol Drugs 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229950000339 xinafoate Drugs 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
- B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0015—Devices specially adapted for taking medicines
- A61J7/0046—Cups, bottles or bags
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
- B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
- B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
- B65D51/2814—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
- B65D51/2821—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being a blister, a capsule or like sealed container
Definitions
- the present invention relates to a medicament dispenser.
- the present invention is directed to a medicament dispenser that can be used conveniently and 5 at any desired location.
- the invention provides a medicament dispenser comprising a container body having an opening from which to access the contents of said body, the exterior of said body having at least one pressure point for communication with a blister containing a medicament and/or a dietary supplement, such that application of pressure to the pressure point breaks the blister and so o liberates the medicament and/or dietary supplement into the interior of said container body.
- the pressure point can in one embodiment form part of the blister and the applied pressure act such as to rupture the blister.
- the blister has a peelable seal such that access thereto is by application of peeling pressure.
- Other variations are envisaged comprising other known blister pack types.
- the dispenser may be in the form of a flat-pack for assembly into a container body.
- a consumer would have a dispenser on his/her person, or buy such a dispenser, assemble it into a container body, fill with liquid for aiding ingestion of the medicament or dietary supplement, liberate the contents of the blister pack supplied on the container body and consume the resulting mixture.
- the container body is filled with a beverage.
- the beverage may be selected from water, mineral water, fruit juice, a soft drink or tonic.
- the tonic may be a high energy tonic possibly including a stimulant such as caffeine or taurine; or a soluble vitamin such as vitamin C.
- a consumer would have a quick and convenient way of taking a medicament/dietary supplement at any time and at any place, for example, whether on public transport, in an elevator or during a business meeting.
- the container body further comprises a removable lid.
- the at least one pressure point is located on the removable lid.
- the blister may comprise a single independent dose of medicament and/or dietary supplement in a single blister.
- the blister may form part of a blister pack comprising a plurality of blisters so that the dispenser comprises a plurality of independent doses of medicament and/or dietary supplement, that is, one dose is disposed in each blister.
- each blister in a blister pack may contain a dose of medicament and a dietary supplement such as one or more vitamins and/or caffeine and/or taurine.
- a dietary supplement such as one or more vitamins and/or caffeine and/or taurine.
- the medicament and/or dietary supplement may be in tablet, capsule, powder or liquid form.
- the medicament and/or dietary supplement are in tablet form.
- the container body has a neck member about which the removable lid fits thereover.
- the blister may have an adhesive backing suitable for attachment to the neck of the container body.
- the removable lid is rotatable about the neck member and container body.
- the lid may comprise an annulus rotatable about an axis central to the lid, neck and container body, on which the at least one pressure point is located, such that the at least one pressure point is rotatable relative to the lid, the neck and the container body.
- the consumer would be able to rotate the lid and/or annulus relative to the container body in order to align a pressure point with the next full blister.
- the blister is on the dispenser, either as an integral part thereof or add-on feature thereto.
- the removable lid may be securable to the container body by a clip-on, and/or snap- fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
- the opening for access to the contents of the container body is in situ on the removable lid.
- the access opening is removably sealable with a cover member.
- the cover member may be securable to the lid by a clip-on, and/or snap-fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
- the cover is attached to the lid by a flexible linkage.
- the invention a container body for use with the medicament dispenser as described hereinabove.
- the invention provides a kit of parts comprising a container body, a dose of medicament and a beverage in which to mix the medicament.
- Figure 1 shows a flat pack medicament dispenser in accordance with one aspect of the invention
- Figure 2 shows a disposable water-filled medicament dispenser in accordance with another aspect of the invention
- FIG 3 shows a refillable medicament dispenser in accordance with yet another aspect of the invention
- Figures 4a and 4b shows a variation of the flat pack medicament dispenser of Figure 1.
- a flat-pack version of the dispenser 2 is illustrated in Figure 1.
- the flat-pack is simply squeezed (in the direction of the arrows) to open out the carton material into the shape of a beverage container.
- a pressure point 4 is located on the side of the exterior of the container.
- a tablet of medicament housed inside a blister pack (not shown) on the other side of the pressure point, expels the tablet into the interior of the container.
- the medicament can be consumed quickly and easily.
- the medicament dispenser 6 illustrated in Figure 2 is a disposable unit.
- the container body 8 is already filled with a beverage, such as mineral water 10.
- a pressure point 12 on the exterior of the unit is linked to a single blister pack 14 housing one dose of medicament 16.
- the blister pack 14 housing is located at a position somewhat above the normal fluid fill position of the 5 container body 8 to minimise the time of fluid immersion before consumption. Release of the medicament into the beverage by the application of pressure to the pressure point results in a single dose for consumption.
- This unit is especially useful for people who may suffer from ailments such as colds, influenza, hayfever and so on and can be seen as an instant remedy for people with busy lives.
- Figure 3 illustrates a refillable, reusable medicament dispenser 20.
- an adhesive-backed blister pack 22 containing a plurality of discrete doses, one in each blister, to the dispenser and filling it with a liquid of choice the unit may be used throughout the day, for example, when regular doses of pain-killers are required.
- the container body 24 is interchangeable in this embodiment so that different dosages and configurations can be adopted to suit the consumer.
- the dispenser 20 comprises the container body 24 having a neck 26 for attachment of the strip of blisters 22 containing the medicament of choice.
- a lid 28 Around and on top of o the neck is fitted a lid 28 which clips snugly onto the container body.
- a protective cover 32 can then be removed from the top of the lid and the medicament and liquid be consumed by the user.
- Figures 4a and 4b respectively show front and back unfolded (i.e. disassembled) views of a medicament dispenser 2 of a type similar to that shown in Figure 1. It may be appreciated that when assembled by folding and adhesively joining at respective join portions 3a, 3b and 3c a flat-pack beverage container is formed. Pressure point 4 may be clearly seen on the front of the dispenser pack as may the blister pack 5 on the other side of the pressure point 4. Access to the blister pack is by application of user pressure to the pressure point 4 to expel the medicament (e.g. in tablet form) therein into the container body.
- the medicament e.g. in tablet form
- Appropriate medicaments for dispensing may be selected from, for example, analgesics, e.g., codeine, dihydromorphine, ergotamine, fentanyl or morphine; anginal preparations, e.g., diltiazem; antiallergics, e.g., cromoglycate (eg s the sodium salt), ketotifen or nedocromil (eg as the sodium salt); antiinfectives e.g., cephalosporins, penicillins, streptomycin, sulphonamides, tetracyclines and pentamidine; antihistamines, e.g., methapyrilene; anti- inflammatories, e.g., beclomethasone (eg as the dipropionate ester), fluticasone (eg as the propionate ester), flunisolide, budesonide, rofleponide, mometasone
- ⁇ 4 integrin inhibitors eg (2S)-3-[4-( ⁇ [4-(aminocarbonyl)-1- piperidinyl]carbonyl ⁇ oxy)phenyl]-2-[((2S)-4-methyl-2- ⁇ [2-(2-methylphenoxy) acetyl]amino ⁇ pentanoyljamino] propanoic acid (e.g as free acid or potassium salt), diuretics, e.g., amiloride; anticholinergics, e.g., ipratropium (eg as bromide), tiotropium, atropine or oxitropium; hormones, e.g., cortisone, hydrocortisone or prednisolone; xanthines, e.g., aminophylline, choline theophyllinate, lysine theophyllinate or theophylline; therapeutic proteins and peptides, e.g., insulin or gluca
- the medicaments may be used in the form of salts, (e.g., as alkali metal or amine salts or as acid addition salts) or as esters (e.g., lower alkyl esters) or as solvates (e.g., hydrates) to optimise the activity and/or stability of the medicament.
- salts e.g., as alkali metal or amine salts or as acid addition salts
- esters e.g., lower alkyl esters
- solvates e.g., hydrates
- any of the parts of the dispenser may be coated with materials such as fluoropolymer materials which reduce the tendency of medicament to adhere thereto.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
There is provided a medicament dispenser comprising a container body having an opening from which to access the contents of said body, the exterior of said body having at least one pressure point for communication with a blister pack containing a medicament and/or a dietary supplement, such that application of pressure to the pressure point breaks the blister and so liberates the medicament and/or dietary supplement into the interior of said container body.
Description
Medicament Dispenser
The present invention relates to a medicament dispenser. In particular, the present invention is directed to a medicament dispenser that can be used conveniently and 5 at any desired location.
As a result of today's hectic and pressurised lifestyle there is an increasing uptake of pain killers, indigestiόn/heartbum/upset-stomach remedies, sedatives, dietary supplements, herbal remedies and other medicaments on a daily and sometimes, 0 multi-daily basis. A major problem for people not at home, for example, at work or in transit (e.g on public transport), is the availability of the medicament, or most likely, a convenient way of ingesting a dose; very often a glass of water or even a container to fill with water are far from at hand.
5 An object of the present invention is to provide a medicament dispenser which solves the problem of finding a container and/or fluid to consume a medicament/dietary supplement. Another object of the present invention is to provide a dispenser that can be stored in flat pack form prior to use and therefore present a convenient and space-conscious option to carrying a bottle of medicament 0 and a glass on one's person. Another object of the invention is to provide either a disposable one-dose medicament dispenser and/or a dispenser that that be used indefinitely by refilling the medicament or substance to be ingested into the dosing mechanism.
5 Accordingly, in one aspect, the invention provides a medicament dispenser comprising a container body having an opening from which to access the contents of said body, the exterior of said body having at least one pressure point for communication with a blister containing a medicament and/or a dietary supplement, such that application of pressure to the pressure point breaks the blister and so o liberates the medicament and/or dietary supplement into the interior of said container body.
The pressure point can in one embodiment form part of the blister and the applied pressure act such as to rupture the blister. In another embodiment, the blister has a peelable seal such that access thereto is by application of peeling pressure. Other variations are envisaged comprising other known blister pack types.
In one embodiment, the dispenser may be in the form of a flat-pack for assembly into a container body.
Therefore, it can be envisaged that a consumer would have a dispenser on his/her person, or buy such a dispenser, assemble it into a container body, fill with liquid for aiding ingestion of the medicament or dietary supplement, liberate the contents of the blister pack supplied on the container body and consume the resulting mixture.
Preferably, the container body is filled with a beverage.
For example, the beverage may be selected from water, mineral water, fruit juice, a soft drink or tonic. The tonic may be a high energy tonic possibly including a stimulant such as caffeine or taurine; or a soluble vitamin such as vitamin C.
In this embodiment, a consumer would have a quick and convenient way of taking a medicament/dietary supplement at any time and at any place, for example, whether on public transport, in an elevator or during a business meeting.
Typically, the container body further comprises a removable lid.
Preferably, the at least one pressure point is located on the removable lid.
The blister may comprise a single independent dose of medicament and/or dietary supplement in a single blister.
Suitably, the blister may form part of a blister pack comprising a plurality of blisters so that the dispenser comprises a plurality of independent doses of medicament and/or dietary supplement, that is, one dose is disposed in each blister.
Typically, each blister in a blister pack may contain a dose of medicament and a dietary supplement such as one or more vitamins and/or caffeine and/or taurine.
The medicament and/or dietary supplement may be in tablet, capsule, powder or liquid form. Preferably, the medicament and/or dietary supplement are in tablet form.
In another embodiment, the container body has a neck member about which the removable lid fits thereover.
Typically, the blister may have an adhesive backing suitable for attachment to the neck of the container body.
In one embodiment, the removable lid is rotatable about the neck member and container body.
Alternatively, the lid may comprise an annulus rotatable about an axis central to the lid, neck and container body, on which the at least one pressure point is located, such that the at least one pressure point is rotatable relative to the lid, the neck and the container body.
In these embodiments, the consumer would be able to rotate the lid and/or annulus relative to the container body in order to align a pressure point with the next full blister.
Preferably, the blister is on the dispenser, either as an integral part thereof or add-on feature thereto.
The removable lid may be securable to the container body by a clip-on, and/or snap- fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
Typically, the opening for access to the contents of the container body is in situ on the removable lid.
Preferably, the access opening is removably sealable with a cover member.
The cover member may be securable to the lid by a clip-on, and/or snap-fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
In a preferred embodiment, the cover is attached to the lid by a flexible linkage.
In another aspect, the invention a container body for use with the medicament dispenser as described hereinabove.
In yet another aspect, the invention provides a kit of parts comprising a container body, a dose of medicament and a beverage in which to mix the medicament.
The invention will now be described further with reference to the accompanying drawings in which:
Figure 1 shows a flat pack medicament dispenser in accordance with one aspect of the invention; Figure 2 shows a disposable water-filled medicament dispenser in accordance with another aspect of the invention;
Figure 3 shows a refillable medicament dispenser in accordance with yet another aspect of the invention; and, Figures 4a and 4b shows a variation of the flat pack medicament dispenser of Figure 1.
Referring now to the figures, a flat-pack version of the dispenser 2 is illustrated in Figure 1. The flat-pack is simply squeezed (in the direction of the arrows) to open out the carton material into the shape of a beverage container. A pressure point 4 is located on the side of the exterior of the container. By pushing the pressure point 5 with a thumb or finger, a tablet of medicament housed inside a blister pack (not shown) on the other side of the pressure point, expels the tablet into the interior of the container. By filling the container body with water or another liquid of choice, the medicament can be consumed quickly and easily.
0 The medicament dispenser 6 illustrated in Figure 2 is a disposable unit. The container body 8 is already filled with a beverage, such as mineral water 10. A pressure point 12 on the exterior of the unit is linked to a single blister pack 14 housing one dose of medicament 16. It should be noted that the blister pack 14 housing is located at a position somewhat above the normal fluid fill position of the 5 container body 8 to minimise the time of fluid immersion before consumption. Release of the medicament into the beverage by the application of pressure to the pressure point results in a single dose for consumption. This unit is especially useful for people who may suffer from ailments such as colds, influenza, hayfever and so on and can be seen as an instant remedy for people with busy lives. 0
Figure 3 illustrates a refillable, reusable medicament dispenser 20. By attaching an adhesive-backed blister pack 22 containing a plurality of discrete doses, one in each blister, to the dispenser and filling it with a liquid of choice, the unit may be used throughout the day, for example, when regular doses of pain-killers are required. 5 The container body 24 is interchangeable in this embodiment so that different dosages and configurations can be adopted to suit the consumer.
The dispenser 20 comprises the container body 24 having a neck 26 for attachment of the strip of blisters 22 containing the medicament of choice. Around and on top of o the neck is fitted a lid 28 which clips snugly onto the container body.
On the exterior surface of the lid at points directly opposite each other are two pressure points 30. Application of pressure at these points when the lid is in position on the container body, results in the breaking of two blisters of medicament into the interior of the container body.
A protective cover 32 can then be removed from the top of the lid and the medicament and liquid be consumed by the user.
Figures 4a and 4b respectively show front and back unfolded (i.e. disassembled) views of a medicament dispenser 2 of a type similar to that shown in Figure 1. It may be appreciated that when assembled by folding and adhesively joining at respective join portions 3a, 3b and 3c a flat-pack beverage container is formed. Pressure point 4 may be clearly seen on the front of the dispenser pack as may the blister pack 5 on the other side of the pressure point 4. Access to the blister pack is by application of user pressure to the pressure point 4 to expel the medicament (e.g. in tablet form) therein into the container body.
Appropriate medicaments for dispensing may be selected from, for example, analgesics, e.g., codeine, dihydromorphine, ergotamine, fentanyl or morphine; anginal preparations, e.g., diltiazem; antiallergics, e.g., cromoglycate (eg s the sodium salt), ketotifen or nedocromil (eg as the sodium salt); antiinfectives e.g., cephalosporins, penicillins, streptomycin, sulphonamides, tetracyclines and pentamidine; antihistamines, e.g., methapyrilene; anti- inflammatories, e.g., beclomethasone (eg as the dipropionate ester), fluticasone (eg as the propionate ester), flunisolide, budesonide, rofleponide, mometasone eg as the furoate ester), ciclesonide, triamcinolone (eg as the acetonide) or 6α, 9α-difluoro-11β-hydroxy-16α- methyl-3-oxo-17α-propionyloxy-androsta-1 ,4-diene-17β-carbothioic acid S-(2-oxo- tetrahydro-furan-3-yl) ester; antitussives, e.g., noscapine; bronchodilators, e.g., albuterol (eg as free base or sulphate), salmeterol (eg as xinafoate), ephedrine, adrenaline, fenoterol (eg as hydrobromide), formoterol (eg as fumarate), isoprenaline, metaproterenol, phenylephrine, phenylpropanolamine, pirbuterol (eg as
acetate), reproterol (eg as hydrochloride), rimiterol, terbutaline (eg as sulphate), isoetharine, tulobuterol or 4-hydroxy-7-[2-[[2-[[3-(2- phenylethoxy)propyl]sulfonyl]ethyl]amino]ethyl-2(3H)-benzothiazolone; adenosine 2a agonists, eg 2R,3R,4S,5R)-2-[6-Amino-2-(1 S-hydroxymethyl-2-phenyl-ethylamino)- purin-9-yl]-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol (e.g. as maleate); α4 integrin inhibitors eg (2S)-3-[4-({[4-(aminocarbonyl)-1- piperidinyl]carbonyl}oxy)phenyl]-2-[((2S)-4-methyl-2-{[2-(2-methylphenoxy) acetyl]amino}pentanoyljamino] propanoic acid (e.g as free acid or potassium salt), diuretics, e.g., amiloride; anticholinergics, e.g., ipratropium (eg as bromide), tiotropium, atropine or oxitropium; hormones, e.g., cortisone, hydrocortisone or prednisolone; xanthines, e.g., aminophylline, choline theophyllinate, lysine theophyllinate or theophylline; therapeutic proteins and peptides, e.g., insulin or glucagon; vaccines, diagnostics, and gene therapies. It will be clear to a person skilled in the art that, where appropriate, the medicaments may be used in the form of salts, (e.g., as alkali metal or amine salts or as acid addition salts) or as esters (e.g., lower alkyl esters) or as solvates (e.g., hydrates) to optimise the activity and/or stability of the medicament.
It may be appreciated that any of the parts of the dispenser may be coated with materials such as fluoropolymer materials which reduce the tendency of medicament to adhere thereto.
It will be understood that the present disclosure is for the purpose of illustration only and the invention extends to modifications, variations and improvements thereto.
The application of which this description and claims form part may be used as a basis for priority in respect of any subsequent application. The claims of such subsequent application may be directed to any feature or combination of features described therein. They may take the form of product, method or use claims and may include, by way of example and without limitation, one or more of the following claims:
Claims
1. A medicament dispenser comprising a container body having an opening from which to access the contents of said body, the exterior of said body having at least 5 one pressure point for communication with a blister pack containing a medicament and/or a dietary supplement, such that application of pressure to the pressure point breaks the blister and so liberates the medicament and/or dietary supplement into the interior of said container body.
0 2. A medicament dispenser according to claim 1 which is in the form of a flat- pack for assembly into a container body.
3. A medicament dispenser according to claim 1 or claim 2 wherein the container body is filled with a beverage. 5
4. A medicament dispenser according to claim 3 wherein the beverage is selected from water, mineral water, fruit juice, a soft drink or tonic.
5. A medicament dispenser according to any one of the preceding claims 0 wherein the container body further comprises a removable lid.
6. A medicament dispenser according to claim 5 wherein the at least one pressure point is located on the removable lid.
5 7. A medicament dispenser according to any one of claims 1 to 6 wherein the blister comprises a single independent dose of medicament and/or dietary supplement.
8. A medicament dispenser according to any one of claims 1 to 6 wherein the o blister forms part of a blister pack comprising a plurality of blisters.
9. A medicament dispenser according to any one of claims 5 to 8 wherein the container body has a neck member about which the removable lid fits thereover.
10. A medicament dispenser according to claim 9 wherein the blister has an adhesive backing suitable for attachment to the neck of the container body.
11. A medicament dispenser according to any one of claims 7 to 10 wherein the removable lid is rotatable about the neck member and container body.
12. A medicament dispenser according to any one of claims 7 to 10 wherein the lid comprises an annulus rotatable about an axis central to the lid, neck and container body, on which the at least one pressure point is located, such that the at least one pressure point is rotatable relevant to the lid, the neck and the container body.
13. A medicament dispenser according to any one of the preceding claims including the blister pack.
14. A medicament dispenser according to any one of claims 5 to 13 wherein the removable lid is securable to the container body by a clip-on, and/or snap-fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
15. A medicament dispenser according to any one of claims 5 to 14 wherein the opening for access to the contents of the container body is in situ on the removable lid.
16. A medicament dispenser according to claim 15 wherein the access opening is removably sealable with a cover member.
17. A medicament dispenser according to claim 16 wherein the cover member is securable to the lid by a clip-on, and/or snap-fit, and/or thread and bore (screw-on), and/or bayonet arrangement.
18. A medicament dispenser according to claim 16 or claim 17 wherein the cover is attached to the lid by, a flexible linkage.
19. A medicament dispenser substantially as claimed hereinabove and with reference to the accompanying drawings.
20. A container body for use with the medicament dispenser according to any one of the preceding claims.
21. A container body substantially as claimed hereinabove and with reference to the accompanying drawings.
22. A kit of parts comprising a container body, a dose of medicament and a beverage in which to mix the medicament.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0110485A GB0110485D0 (en) | 2001-04-28 | 2001-04-28 | Medicament dispenser |
| GB0110485 | 2001-04-28 | ||
| PCT/EP2002/003323 WO2002087489A1 (en) | 2001-04-28 | 2002-03-25 | Medicament dispenser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1383457A1 true EP1383457A1 (en) | 2004-01-28 |
Family
ID=9913683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02727472A Withdrawn EP1383457A1 (en) | 2001-04-28 | 2002-03-25 | Medicament dispenser |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1383457A1 (en) |
| JP (1) | JP2004528107A (en) |
| GB (1) | GB0110485D0 (en) |
| WO (1) | WO2002087489A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2278332A1 (en) | 2009-07-20 | 2011-01-26 | Fondazione Centro San Raffaele del Monte Tabor | Method for optical measuring variations of cell membrane conductance |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1261684A (en) * | 1959-07-14 | 1961-05-19 | Chesebrough Ponds | Squeeze bottle in synthetic resin |
| AUPO070596A0 (en) * | 1996-06-27 | 1996-07-18 | Gartner, Bradley Francis | Closure cap |
| US6105760A (en) * | 1997-10-14 | 2000-08-22 | Mollstam; Bo | Two-compartment package |
| AU6356799A (en) * | 1998-10-26 | 2000-05-15 | Peter Thomas Bowdler | Tablet package |
-
2001
- 2001-04-28 GB GB0110485A patent/GB0110485D0/en not_active Ceased
-
2002
- 2002-03-25 JP JP2002584843A patent/JP2004528107A/en active Pending
- 2002-03-25 WO PCT/EP2002/003323 patent/WO2002087489A1/en not_active Ceased
- 2002-03-25 EP EP02727472A patent/EP1383457A1/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| See references of WO02087489A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0110485D0 (en) | 2001-06-20 |
| JP2004528107A (en) | 2004-09-16 |
| WO2002087489A1 (en) | 2002-11-07 |
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