EP1379233A4 - Use of a substantially cell membrane impermeable compound for treating arthritis - Google Patents

Use of a substantially cell membrane impermeable compound for treating arthritis

Info

Publication number
EP1379233A4
EP1379233A4 EP02704485A EP02704485A EP1379233A4 EP 1379233 A4 EP1379233 A4 EP 1379233A4 EP 02704485 A EP02704485 A EP 02704485A EP 02704485 A EP02704485 A EP 02704485A EP 1379233 A4 EP1379233 A4 EP 1379233A4
Authority
EP
European Patent Office
Prior art keywords
cell membrane
treating arthritis
substantially cell
membrane impermeable
impermeable compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02704485A
Other languages
German (de)
French (fr)
Other versions
EP1379233A1 (en
Inventor
Philip John Hogg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NewSouth Innovations Pty Ltd
Original Assignee
Unisearch Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unisearch Ltd filed Critical Unisearch Ltd
Publication of EP1379233A1 publication Critical patent/EP1379233A1/en
Publication of EP1379233A4 publication Critical patent/EP1379233A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/285—Arsenic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP02704485A 2001-03-19 2002-03-19 Use of a substantially cell membrane impermeable compound for treating arthritis Withdrawn EP1379233A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPR3798A AUPR379801A0 (en) 2001-03-19 2001-03-19 Use of a substantially cell membrane impermeable compound for treating arthritis
AUPP379801 2001-03-19
PCT/AU2002/000310 WO2002074305A1 (en) 2001-03-19 2002-03-19 Use of a substantially cell membrane impermeable compound for treating arthritis

Publications (2)

Publication Number Publication Date
EP1379233A1 EP1379233A1 (en) 2004-01-14
EP1379233A4 true EP1379233A4 (en) 2005-10-26

Family

ID=3827806

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02704485A Withdrawn EP1379233A4 (en) 2001-03-19 2002-03-19 Use of a substantially cell membrane impermeable compound for treating arthritis

Country Status (4)

Country Link
US (1) US7186695B2 (en)
EP (1) EP1379233A4 (en)
AU (1) AUPR379801A0 (en)
WO (1) WO2002074305A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ296799A0 (en) * 1999-09-20 1999-10-14 Unisearch Limited A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
EP1474128B1 (en) 2002-01-07 2016-06-01 Board Of Regents, The University Of Texas System S-dimethylarsino-thiosuccinic acid, s-dimethylarsino-2-thiobenzoic acid, s-(dimethylarsino)glutathione as treatments for cancer
ES2330519T3 (en) 2002-11-07 2009-12-11 Newsouth Innovations Pty Limited MITOCONDRIAL PERMEABILITY TRANSITION INDICATION.
FR2858216B1 (en) * 2003-07-31 2008-04-04 Oreal COMPOSITION COMPRISING A 2-THIOACETAMIDE, ITS USE FOR STIMULATING THE PUSH OF KERATIN FIBERS AND / OR BRAKING THEIR FALL
CA2668010C (en) 2006-11-01 2015-03-24 Newsouth Innovations Pty Limited Organo-arsenoxide compounds and use thereof
WO2009043114A1 (en) * 2007-10-04 2009-04-09 Newsouth Innovations Pty Limited Arsenoxide compound and method of use
WO2010071865A1 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2011032175A1 (en) 2009-09-14 2011-03-17 Nuon Therapeutics, Inc. Combination formulations of tranilast and allopurinol and methods related thereto
WO2013126587A1 (en) 2012-02-21 2013-08-29 Cytonics Corporation Systems, compositions, and methods for transplantation
US9352021B2 (en) 2013-08-28 2016-05-31 Cytonics Corporation Systems, compositions, and methods for transplantation and treating conditions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021628A1 (en) * 1999-09-20 2001-03-29 Unisearch Limited A substantially cell membrane impermeable compound and use thereof
WO2003003011A1 (en) * 2001-06-28 2003-01-09 Unisearch Limited Modification of angiogenesis by targeting protein tyrosine phosphatases
WO2003039564A1 (en) * 2001-11-08 2003-05-15 Unisearch Limited Selective targeting of apoptotic cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883659A (en) 1973-05-18 1975-05-13 Ciba Geigy Corp 9-Oxaprostaglandin compositions
WO1998051297A1 (en) 1997-05-14 1998-11-19 The University Of New Mexico Inhibition of cell surface protein disulfide isomerase
PT1391206E (en) 1997-10-15 2008-08-13 Polarx Biopharmaceuticals Inc Pharmaceutical compositions comprising arsenic trioxide for the treatment of non-hodgkin`s lymphoma
CN1233476A (en) 1998-04-24 1999-11-03 陆道培 Medicine for treating acute leukemia, and method for preparing same
FR2781674B1 (en) 1998-07-31 2002-06-28 Inst Nat Sante Rech Med USE OF NEW CELL DEATH INDUCING AGENTS IN SYNERGY WITH INTERFERONS
US6191123B1 (en) 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021628A1 (en) * 1999-09-20 2001-03-29 Unisearch Limited A substantially cell membrane impermeable compound and use thereof
WO2003003011A1 (en) * 2001-06-28 2003-01-09 Unisearch Limited Modification of angiogenesis by targeting protein tyrosine phosphatases
WO2003039564A1 (en) * 2001-11-08 2003-05-15 Unisearch Limited Selective targeting of apoptotic cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DONOGHUE, NEIL ET AL: "Presence of closely spaced protein thiols on the surface of mammalian cells", PROTEIN SCIENCE , 9(12), 2436-2445 CODEN: PRCIEI; ISSN: 0961-8368, 2000, XP002342335 *
See also references of WO02074305A1 *

Also Published As

Publication number Publication date
WO2002074305A1 (en) 2002-09-26
AUPR379801A0 (en) 2001-04-12
US20040138102A1 (en) 2004-07-15
EP1379233A1 (en) 2004-01-14
US7186695B2 (en) 2007-03-06

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20031017

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 47/48 B

Ipc: 7A 61P 19/02 B

Ipc: 7A 61K 49/00 B

Ipc: 7A 61K 31/285 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050908

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NEWSOUTH INNOVATIONS PTY LIMITED

17Q First examination report despatched

Effective date: 20061010

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070421