EP1367998A4 - Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies - Google Patents

Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies

Info

Publication number
EP1367998A4
EP1367998A4 EP01981317A EP01981317A EP1367998A4 EP 1367998 A4 EP1367998 A4 EP 1367998A4 EP 01981317 A EP01981317 A EP 01981317A EP 01981317 A EP01981317 A EP 01981317A EP 1367998 A4 EP1367998 A4 EP 1367998A4
Authority
EP
European Patent Office
Prior art keywords
antibodies
methods
hydrogen peroxide
superoxide production
compositions relating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP01981317A
Other languages
German (de)
French (fr)
Other versions
EP1367998A2 (en
Inventor
Paul Wentworth
Anita D Wentworth
Lyn H Jones
Kim D Janda
Richard A Lerner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of EP1367998A2 publication Critical patent/EP1367998A2/en
Publication of EP1367998A4 publication Critical patent/EP1367998A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • A61K38/446—Superoxide dismutase (1.15)
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    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
EP01981317A 2000-09-15 2001-09-17 Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies Ceased EP1367998A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US23270200P 2000-09-15 2000-09-15
US232702P 2000-09-15
US23547500P 2000-09-26 2000-09-26
US235475P 2000-09-26
US31590601P 2001-08-29 2001-08-29
US315906P 2001-08-29
PCT/US2001/029165 WO2002022573A2 (en) 2000-09-15 2001-09-17 Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies

Publications (2)

Publication Number Publication Date
EP1367998A2 EP1367998A2 (en) 2003-12-10
EP1367998A4 true EP1367998A4 (en) 2004-03-17

Family

ID=27398334

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01981317A Ceased EP1367998A4 (en) 2000-09-15 2001-09-17 Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies

Country Status (5)

Country Link
EP (1) EP1367998A4 (en)
JP (1) JP2005524601A (en)
AU (2) AU1297002A (en)
CA (1) CA2422586A1 (en)
WO (1) WO2002022573A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2381272B (en) 2001-08-22 2003-12-03 Cambridge Theranostics Ltd Diagnosis and treatment of atherosclerosis
CA2505932A1 (en) * 2002-11-14 2004-05-27 Novartis Ag Antimicrobial activity of antibodies producing reactive oxygen species
DE10258239A1 (en) * 2002-12-13 2004-06-24 Degussa Ag Formulation used for treating non-chronic alcoholic intoxication, contains alpha-lipoic acid for scavenging free radicals and activating alcohol metabolizing enzymes
US20050020666A1 (en) * 2003-07-25 2005-01-27 Dabur Research Foundation Cardioprotective agents
JP4615470B2 (en) * 2006-03-29 2011-01-19 卓郎 簑和田 Disease treatment and prevention methods and medicines using cerebral cognition
JPWO2008087803A1 (en) * 2007-01-16 2010-05-06 国立大学法人北海道大学 Liposome preparation for iontophoresis encapsulating antioxidant components
AR095398A1 (en) 2013-03-13 2015-10-14 Genentech Inc FORMULATIONS WITH REDUCED OXIDATION
US10653779B2 (en) 2013-03-13 2020-05-19 Genentech, Inc. Formulations with reduced oxidation
CN110075293A (en) * 2013-03-13 2019-08-02 霍夫曼-拉罗奇有限公司 Aoxidize reduced preparaton
JP6269946B2 (en) * 2014-03-25 2018-01-31 国立大学法人名古屋大学 Bacterial growth inhibition
KR101774636B1 (en) * 2015-04-06 2017-09-04 한국생명공학연구원 Method for Label-free antibody detection basd on nano probe
US20210393700A1 (en) * 2017-11-29 2021-12-23 Figene, Llc Interaction of fibroblasts and immune cells for activation and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998025645A1 (en) * 1996-12-12 1998-06-18 Karolinska Innovation Ab Therapeutic applications of antigens or epitopes associated with impaired cellular peptide processing, e.g. expressed on rma-s cells transfected with a b7-1 gene

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Publication number Priority date Publication date Assignee Title
US5162217A (en) * 1984-08-27 1992-11-10 Bio-Technology General Corp. Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof
US5248603A (en) * 1985-09-03 1993-09-28 Symbicom Aktiebolag Superoxide dismutase
FR2656866B1 (en) * 1990-01-10 1992-05-15 Cis Bio Int PORPHYRIN DERIVATIVES AND METALLOPORPHYRINS POTENTIALLY COUPLED TO A BIOLOGICALLY ACTIVE MOLECULE, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.
DE4038563A1 (en) * 1990-12-04 1992-06-11 Gruenenthal Gmbh USE OF SUPEROXIDE DISMUTASES FOR PROPHYLAXIS AND / OR TREATMENT OF ORGAN FAILURE IN RISK PATIENTS WITH POLYTRAUMA
US5637315A (en) * 1993-01-04 1997-06-10 Thomas Jefferson University Treatment of disease states induced by oxidative stress
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
DE4407047A1 (en) * 1994-03-03 1995-09-07 Merck Patent Gmbh Acetamide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998025645A1 (en) * 1996-12-12 1998-06-18 Karolinska Innovation Ab Therapeutic applications of antigens or epitopes associated with impaired cellular peptide processing, e.g. expressed on rma-s cells transfected with a b7-1 gene

Also Published As

Publication number Publication date
WO2002022573A2 (en) 2002-03-21
CA2422586A1 (en) 2002-03-21
AU2002212970B2 (en) 2007-05-31
WO2002022573A3 (en) 2003-10-02
AU1297002A (en) 2002-03-26
JP2005524601A (en) 2005-08-18
EP1367998A2 (en) 2003-12-10

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