EP1360560A4 - Representation de la selectivite de recepteurs - Google Patents

Representation de la selectivite de recepteurs

Info

Publication number
EP1360560A4
EP1360560A4 EP00928364A EP00928364A EP1360560A4 EP 1360560 A4 EP1360560 A4 EP 1360560A4 EP 00928364 A EP00928364 A EP 00928364A EP 00928364 A EP00928364 A EP 00928364A EP 1360560 A4 EP1360560 A4 EP 1360560A4
Authority
EP
European Patent Office
Prior art keywords
receptor selectivity
selectivity mapping
mapping
receptor
selectivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00928364A
Other languages
German (de)
English (en)
Other versions
EP1360560A2 (fr
Inventor
David M Manyak
Renee A Zeppetello
Hao Chen
Arthur D Weissman
Garry L Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novascreen Biosciences Corp
Original Assignee
Novascreen Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novascreen Biosciences Corp filed Critical Novascreen Biosciences Corp
Publication of EP1360560A2 publication Critical patent/EP1360560A2/fr
Publication of EP1360560A4 publication Critical patent/EP1360560A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/90Programming languages; Computing architectures; Database systems; Data warehousing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30Drug targeting using structural data; Docking or binding prediction
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/10Ontologies; Annotations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50Molecular design, e.g. of drugs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Databases & Information Systems (AREA)
  • Computing Systems (AREA)
  • Bioethics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Software Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP00928364A 1999-04-26 2000-04-26 Representation de la selectivite de recepteurs Withdrawn EP1360560A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13099299P 1999-04-26 1999-04-26
US130992P 1999-04-26
PCT/US2000/011073 WO2000065421A2 (fr) 1999-04-26 2000-04-26 Representation de la selectivite de recepteurs

Publications (2)

Publication Number Publication Date
EP1360560A2 EP1360560A2 (fr) 2003-11-12
EP1360560A4 true EP1360560A4 (fr) 2007-07-18

Family

ID=22447376

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00928364A Withdrawn EP1360560A4 (fr) 1999-04-26 2000-04-26 Representation de la selectivite de recepteurs

Country Status (5)

Country Link
EP (1) EP1360560A4 (fr)
JP (1) JP2004500614A (fr)
AU (1) AU4661300A (fr)
CA (1) CA2371093A1 (fr)
WO (1) WO2000065421A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4553443B2 (ja) * 2000-03-15 2010-09-29 文章 大谷 触媒の探索方法
CA2425488A1 (fr) * 2000-10-12 2002-04-18 Iconix Pharmaceuticals, Inc Correlation interactive de donnees de compose et de donnees genomiques
US20030120430A1 (en) * 2001-12-03 2003-06-26 Icagen, Inc. Method for producing chemical libraries enhanced with biologically active molecules
EP1603585A2 (fr) 2003-03-14 2005-12-14 Bristol-Myers Squibb Company Polynucleotide codant un nouveau variant de recepteur de hm74, hgprbmy74 couple a une proteine g humaine
AU2003276930A1 (en) * 2003-03-24 2004-11-23 Novascreen Biosciences Corporation Drug discovery method and apparatus
US7588892B2 (en) 2004-07-19 2009-09-15 Entelos, Inc. Reagent sets and gene signatures for renal tubule injury
US7467118B2 (en) 2006-01-12 2008-12-16 Entelos Inc. Adjusted sparse linear programming method for classifying multi-dimensional biological data
JP7398334B2 (ja) * 2020-04-30 2023-12-14 株式会社日立製作所 ユーザに提案する材料を決定するシステム
CN111696623B (zh) * 2020-05-28 2023-06-13 上海药明康德新药开发有限公司 一种基于dna编码化合物库的实验室信息管理系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5025388A (en) * 1988-08-26 1991-06-18 Cramer Richard D Iii Comparative molecular field analysis (CoMFA)
US5434796A (en) * 1993-06-30 1995-07-18 Daylight Chemical Information Systems, Inc. Method and apparatus for designing molecules with desired properties by evolving successive populations
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BROWN F K: "CHEMOINFORMATICS: WHAT IS IT AND HOW DOES IT IMPACT DRUG DISCOVERY", 1998, ANNUAL REPORTS IN MEDICINAL CHEMISTRY, SAN DIEGO, US, PAGE(S) 375-384, ISSN: 0065-7743, XP008035536 *
BURBAUM J J ET AL: "NEW TECHNOLOGIES FOR HIGH-THROUGHPUT SCREENING", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 1, no. 1, June 1997 (1997-06-01), pages 72 - 78, XP001029043, ISSN: 1367-5931 *
GOTO SUSUMU ET AL: "LIGAND database for enzymes, compounds and reactions", 1 January 1999, NUCLEIC ACIDS RESEARCH, VOL. 27, NR. 1, PAGE(S) 377-379, ISSN: 0305-1048, XP002436118 *
HEMM K ET AL: "Constituting a receptor-ligand information base from quality-enriched data.", 1995, PROCEEDINGS / ... INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY ; ISMB. INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY 1995, VOL. 3, PAGE(S) 170 - 178, ISSN: 1553-0833, XP002436119 *
SHI L M ET AL: "Mining the NCI anticancer drug discovery databases: genetic function approximation for the QSAR study of anticancer ellipticine analogues.", March 1998, JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES 1998 MAR-APR, VOL. 38, NR. 2, PAGE(S) 189 - 199, ISSN: 0095-2338, XP002436117 *

Also Published As

Publication number Publication date
EP1360560A2 (fr) 2003-11-12
CA2371093A1 (fr) 2000-11-02
AU4661300A (en) 2000-11-10
WO2000065421A3 (fr) 2003-09-12
JP2004500614A (ja) 2004-01-08
WO2000065421A2 (fr) 2000-11-02

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20011123

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20070615

17Q First examination report despatched

Effective date: 20090609

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20091020