EP1333862A2 - Verfahren und pharmazeutische zusammensetzungen zur verbesserung der implantation von embryos - Google Patents
Verfahren und pharmazeutische zusammensetzungen zur verbesserung der implantation von embryosInfo
- Publication number
- EP1333862A2 EP1333862A2 EP01978796A EP01978796A EP1333862A2 EP 1333862 A2 EP1333862 A2 EP 1333862A2 EP 01978796 A EP01978796 A EP 01978796A EP 01978796 A EP01978796 A EP 01978796A EP 1333862 A2 EP1333862 A2 EP 1333862A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- heparanase
- embryo
- effective amount
- contacting
- mature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24085700P | 2000-10-17 | 2000-10-17 | |
| US240857P | 2000-10-17 | ||
| PCT/IL2001/000950 WO2002032283A2 (en) | 2000-10-17 | 2001-10-15 | Methods of and pharmaceutical compositions for improving implantation of embryos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1333862A2 true EP1333862A2 (de) | 2003-08-13 |
| EP1333862A4 EP1333862A4 (de) | 2004-08-18 |
Family
ID=22908221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP01978796A Withdrawn EP1333862A4 (de) | 2000-10-17 | 2001-10-15 | Verfahren und pharmazeutische zusammensetzungen zur verbesserung der implantation von embryos |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1333862A4 (de) |
| AU (1) | AU2002210887A1 (de) |
| WO (1) | WO2002032283A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6699672B1 (en) | 1997-09-02 | 2004-03-02 | Insight Biopharmaceuticals Ltd. | Heparanase specific molecular probes and their use research and medical applications |
| AU2002216341A1 (en) * | 2000-12-19 | 2002-07-01 | Insight Strategy And Marketing Ltd. | The use of ecm degrading enzymes for the improvement of cell transplantation |
| CN100384481C (zh) * | 2004-11-03 | 2008-04-30 | 上海市计划生育科学研究所 | 胚泡着床相关因子及其用途 |
| CN100415299C (zh) * | 2004-12-22 | 2008-09-03 | 上海市计划生育科学研究所 | 胚泡着床相关因子及其用途 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991002977A1 (en) * | 1989-08-23 | 1991-03-07 | Hadassah Medical Organization | Wound healing preparations containing heparanase |
| WO1999011798A1 (en) * | 1997-09-02 | 1999-03-11 | Insight Strategy & Marketing Ltd. | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
| WO1999021975A1 (en) * | 1997-10-28 | 1999-05-06 | The Australian National University | Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor |
| WO2000052149A1 (en) * | 1999-03-02 | 2000-09-08 | Insight Strategy & Marketing Ltd. | Introducing a biological material into a patient |
-
2001
- 2001-10-15 EP EP01978796A patent/EP1333862A4/de not_active Withdrawn
- 2001-10-15 WO PCT/IL2001/000950 patent/WO2002032283A2/en not_active Application Discontinuation
- 2001-10-15 AU AU2002210887A patent/AU2002210887A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991002977A1 (en) * | 1989-08-23 | 1991-03-07 | Hadassah Medical Organization | Wound healing preparations containing heparanase |
| US5362641A (en) * | 1989-08-23 | 1994-11-08 | Hadassah Medical Organization Kiryat Hadassah | Heparanase derived from human Sk-Hep-1 cell line |
| WO1999011798A1 (en) * | 1997-09-02 | 1999-03-11 | Insight Strategy & Marketing Ltd. | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
| WO1999021975A1 (en) * | 1997-10-28 | 1999-05-06 | The Australian National University | Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor |
| WO2000052149A1 (en) * | 1999-03-02 | 2000-09-08 | Insight Strategy & Marketing Ltd. | Introducing a biological material into a patient |
Non-Patent Citations (5)
| Title |
|---|
| CARSON DANIEL D ET AL: "Mucin and proteoglycan functions in embryo implantation" BIOESSAYS, vol. 20, no. 7, July 1998 (1998-07), pages 577-583, XP002284179 ISSN: 0265-9247 * |
| DEMPSEY L A ET AL: "Heparanase expression in invasive trophoblasts and acute vascular damage" GLYCOBIOLOGY, IRL PRESS,, GB, vol. 10, no. 5, May 2000 (2000-05), pages 467-475, XP002232893 ISSN: 0959-6658 * |
| DEMPSEY L A ET AL: "Heparanase, a potential regulator of cell-matrix interactions." TRENDS IN BIOCHEMICAL SCIENCES. ENGLAND AUG 2000, vol. 25, no. 8, August 2000 (2000-08), pages 349-351, XP004215172 ISSN: 0968-0004 * |
| See also references of WO0232283A2 * |
| VLODAVSKY I ET AL: "EXPRESSION OF HEPARANASE BY PLATELETS AND CIRCULATING CELLS OF THE IMMUNE SYSTEM: POSSIBLE INVOLVEMENT IN DIAPEDESIS AND EXTRAVASATION" INVASION METASTASIS, S. KARGER, BASEL, CH, vol. 12, no. 2, March 1992 (1992-03), pages 112-127, XP001106180 ISSN: 0251-1789 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002032283A3 (en) | 2002-10-31 |
| WO2002032283A2 (en) | 2002-04-25 |
| AU2002210887A1 (en) | 2002-04-29 |
| EP1333862A4 (de) | 2004-08-18 |
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