EP1313466A4 - Bimodal emulsions of taxanes and butyrate polyalcohol esters - Google Patents

Bimodal emulsions of taxanes and butyrate polyalcohol esters

Info

Publication number
EP1313466A4
EP1313466A4 EP01957420A EP01957420A EP1313466A4 EP 1313466 A4 EP1313466 A4 EP 1313466A4 EP 01957420 A EP01957420 A EP 01957420A EP 01957420 A EP01957420 A EP 01957420A EP 1313466 A4 EP1313466 A4 EP 1313466A4
Authority
EP
European Patent Office
Prior art keywords
taxanes
butyrate
polyalcohol esters
bimodal emulsions
bimodal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01957420A
Other languages
German (de)
French (fr)
Other versions
EP1313466A1 (en
Inventor
Steven C Quay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marina Biotech Inc
Original Assignee
Atossa Healthcare Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atossa Healthcare Inc filed Critical Atossa Healthcare Inc
Publication of EP1313466A1 publication Critical patent/EP1313466A1/en
Publication of EP1313466A4 publication Critical patent/EP1313466A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
EP01957420A 2000-08-02 2001-08-02 Bimodal emulsions of taxanes and butyrate polyalcohol esters Withdrawn EP1313466A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63124600A 2000-08-02 2000-08-02
US631246 2000-08-02
PCT/US2001/024359 WO2002009695A1 (en) 2000-08-02 2001-08-02 Bimodal emulsions of taxanes and butyrate polyalcohol esters

Publications (2)

Publication Number Publication Date
EP1313466A1 EP1313466A1 (en) 2003-05-28
EP1313466A4 true EP1313466A4 (en) 2005-11-23

Family

ID=24530377

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01957420A Withdrawn EP1313466A4 (en) 2000-08-02 2001-08-02 Bimodal emulsions of taxanes and butyrate polyalcohol esters

Country Status (4)

Country Link
EP (1) EP1313466A4 (en)
AU (1) AU2001279168A1 (en)
CA (1) CA2417840A1 (en)
WO (1) WO2002009695A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005046237A1 (en) * 2005-09-28 2007-04-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Use of butyrate esters of carbohydrates or carbohydrate polyols as butyrate source for the digestive tract, useful for prevention and treatment of gastrointestinal diseases in humans and animals
SE530420C2 (en) * 2006-09-18 2008-06-03 Perstorp Specialty Chem Ab A waterborne binder composition and its use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
US5877205A (en) * 1996-06-28 1999-03-02 Board Of Regents, The University Of Texas System Parenteral paclitaxel in a stable non-toxic formulation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KAN P ET AL: "Development of nonionic surfactant/phospholipid o/w emulsion as a paclitaxel delivery system", JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 58, no. 3, 19 April 1999 (1999-04-19), pages 271 - 278, XP004166200, ISSN: 0168-3659 *
LUNDBERG B B: "A SUBMICRON LIPID EMULSION COATED WITH AMPHIPATHIC POLYETHYLENE GLYCOL FOR PARENTERAL ADMINISTRATION OF PACLITAXEL (TAXOL)", JOURNAL OF PHARMACY AND PHARMACOLOGY, LONDON, GB, vol. 49, no. 1, 1997, pages 16 - 21, XP000874399, ISSN: 0022-3573 *
See also references of WO0209695A1 *
SIMAMORA P ET AL: "EMULSION FORMULATIONS FOR INTRAVENOUS ADMINISTRATION OF PACLITAXEL", PDA JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, BETHESDA, MD, US, vol. 52, no. 4, 1998, pages 170 - 172, XP000874085, ISSN: 1079-7440 *
TARR B D ET AL: "A NEW PARENTERAL EMULSION FOR THE ADMINISTRATION OF TAXOL", PHARMACEUTICAL RESEARCH (NEW YORK), vol. 4, no. 2, 1987, pages 162 - 165, XP009054519, ISSN: 0724-8741 *

Also Published As

Publication number Publication date
WO2002009695A1 (en) 2002-02-07
EP1313466A1 (en) 2003-05-28
AU2001279168A1 (en) 2002-02-13
CA2417840A1 (en) 2002-02-07

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030221

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20051007

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 9/107 B

Ipc: 7A 61K 31/337 A

17Q First examination report despatched

Effective date: 20060925

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NASTECH PHARMACEUTICAL COMPANY INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20090811