EP1311656A4 - Use of bioactive glass compositions to stimulate osteoblast production - Google Patents

Use of bioactive glass compositions to stimulate osteoblast production

Info

Publication number
EP1311656A4
EP1311656A4 EP01958900A EP01958900A EP1311656A4 EP 1311656 A4 EP1311656 A4 EP 1311656A4 EP 01958900 A EP01958900 A EP 01958900A EP 01958900 A EP01958900 A EP 01958900A EP 1311656 A4 EP1311656 A4 EP 1311656A4
Authority
EP
European Patent Office
Prior art keywords
glass compositions
bioactive glass
stimulate osteoblast
osteoblast production
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01958900A
Other languages
German (de)
French (fr)
Other versions
EP1311656A1 (en
Inventor
Larry L Hench
Julia M Polak
Ioannis D Xynos
Lee Dk Buttery
Jason Maroothynaden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ip2ipo Innovations Ltd
Original Assignee
Imperial College Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial College Innovations Ltd filed Critical Imperial College Innovations Ltd
Publication of EP1311656A1 publication Critical patent/EP1311656A1/en
Publication of EP1311656A4 publication Critical patent/EP1311656A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C03C4/0014—Biodegradable glass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/12—Glass
EP01958900A 2000-07-11 2001-07-11 Use of bioactive glass compositions to stimulate osteoblast production Withdrawn EP1311656A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21746000P 2000-07-11 2000-07-11
US217460P 2000-07-11
PCT/US2001/021801 WO2002004606A1 (en) 2000-07-11 2001-07-11 Use of bioactive glass compositions to stimulate osteoblast production

Publications (2)

Publication Number Publication Date
EP1311656A1 EP1311656A1 (en) 2003-05-21
EP1311656A4 true EP1311656A4 (en) 2009-05-06

Family

ID=22811172

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01958900A Withdrawn EP1311656A4 (en) 2000-07-11 2001-07-11 Use of bioactive glass compositions to stimulate osteoblast production

Country Status (4)

Country Link
EP (1) EP1311656A4 (en)
AU (1) AU2001280507A1 (en)
CA (1) CA2414510A1 (en)
WO (1) WO2002004606A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1592462A1 (en) * 2003-02-14 2005-11-09 The North West London Hospitals NHS Trust Bioactive material for use in stimulating vascularization
GB0526321D0 (en) * 2005-12-23 2006-02-01 Advanced Biotechnologies Inc Silicone composition
DK2224934T3 (en) * 2007-12-21 2012-11-05 Bone Therapeutics Sa Use of osteoblasts for the treatment of inflammatory rheumatic diseases
FR3006195B1 (en) 2013-06-03 2018-03-02 Centre National De La Recherche Scientifique IMPLANT WITH CONTROLLED POROSITY
FR3026309B1 (en) 2014-09-29 2017-11-24 Univ Blaise Pascal-Clermont-Ferrand Ii IMPLANT WITH VARIABLE POROSITY IN A HYBRID MATERIAL
US10238507B2 (en) 2015-01-12 2019-03-26 Surgentec, Llc Bone graft delivery system and method for using same
US10687828B2 (en) 2018-04-13 2020-06-23 Surgentec, Llc Bone graft delivery system and method for using same
US11116647B2 (en) 2018-04-13 2021-09-14 Surgentec, Llc Bone graft delivery system and method for using same
FR3088550B1 (en) 2018-11-15 2021-02-26 Univ Clermont Auvergne CONTROLLED POROSITY IMPLANT IN A HYBRID MATERIAL DOPED IN OSTEOINDUCTIVE NUTRIENT
US11896612B2 (en) 2019-03-29 2024-02-13 Board Of Trustees Of Michigan State University Resurrection of antibiotics that MRSA resists by silver-doped bioactive glass-ceramic particles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU692786B2 (en) * 1993-07-02 1998-06-18 Materials Evolution And Development Usa, Inc. Implantable system for cell growth control
US5538887A (en) * 1994-02-18 1996-07-23 Charlotte-Mecklenburg Hospital Authority Cell culture apparatus having smooth surface for cell growth thereon

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SCHEPERS E ET AL: "BIOACTIVE GLASS PARTICULATE MATERIAL AS A FILLER FOR BONE LESIONS", JOURNAL OF ORAL REHABILITATION, BLACKWELL SCIENTIFIC PUBL., OXFORD, GB, vol. 18, 1 January 1991 (1991-01-01), pages 439 - 452, XP000915889, ISSN: 0305-182X *
See also references of WO0204606A1 *
VROUWENVELDER W C A ET AL: "Behaviour of fetal rat osteoblasts cultured in vitro on bioactive glass and nonreactive glasses", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 13, no. 6, 1 January 1992 (1992-01-01), pages 382 - 392, XP024142235, ISSN: 0142-9612, [retrieved on 19920101] *

Also Published As

Publication number Publication date
WO2002004606A1 (en) 2002-01-17
AU2001280507A1 (en) 2002-01-21
EP1311656A1 (en) 2003-05-21
CA2414510A1 (en) 2002-01-17

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20030205

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20090407

RIC1 Information provided on ipc code assigned before grant

Ipc: A01N 63/00 20060101ALI20090401BHEP

Ipc: C12N 5/00 20060101ALI20090401BHEP

Ipc: A61L 31/08 20060101ALI20090401BHEP

Ipc: A61L 31/02 20060101ALI20090401BHEP

Ipc: A61L 27/32 20060101ALI20090401BHEP

Ipc: A61L 27/10 20060101AFI20090401BHEP

17Q First examination report despatched

Effective date: 20090706

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100119