EP1301631A4 - Novel dna polymerase iii holoenzyme delta subunit nucleic acid molecules and proteins - Google Patents

Novel dna polymerase iii holoenzyme delta subunit nucleic acid molecules and proteins

Info

Publication number
EP1301631A4
EP1301631A4 EP01957164A EP01957164A EP1301631A4 EP 1301631 A4 EP1301631 A4 EP 1301631A4 EP 01957164 A EP01957164 A EP 01957164A EP 01957164 A EP01957164 A EP 01957164A EP 1301631 A4 EP1301631 A4 EP 1301631A4
Authority
EP
European Patent Office
Prior art keywords
proteins
nucleic acid
acid molecules
dna polymerase
polymerase iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP01957164A
Other languages
German (de)
French (fr)
Other versions
EP1301631A1 (en
Inventor
James J Bullard
Nebojsa Janjic
Charles S Mchenry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiovascular Systems Inc
Original Assignee
Replidyne Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/818,780 external-priority patent/US6677146B1/en
Application filed by Replidyne Inc filed Critical Replidyne Inc
Priority to EP06024949A priority Critical patent/EP1816213A3/en
Publication of EP1301631A1 publication Critical patent/EP1301631A1/en
Publication of EP1301631A4 publication Critical patent/EP1301631A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP01957164A 2000-07-14 2001-07-16 Novel dna polymerase iii holoenzyme delta subunit nucleic acid molecules and proteins Ceased EP1301631A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06024949A EP1816213A3 (en) 2000-07-14 2001-07-16 DNA polymerase III holoenzyme delta subunit nucleic acid molecules and proteins

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21824600P 2000-07-14 2000-07-14
US218246P 2000-07-14
US09/818,780 US6677146B1 (en) 2000-03-28 2001-03-28 Thermophilic polymerase III holoenzyme
US818780 2001-03-28
PCT/US2001/022395 WO2002006532A1 (en) 2000-07-14 2001-07-16 Novel dna polymerase iii holoenzyme delta subunit nucleic acid molecules and proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP06024949A Division EP1816213A3 (en) 2000-07-14 2001-07-16 DNA polymerase III holoenzyme delta subunit nucleic acid molecules and proteins

Publications (2)

Publication Number Publication Date
EP1301631A1 EP1301631A1 (en) 2003-04-16
EP1301631A4 true EP1301631A4 (en) 2005-04-13

Family

ID=26912721

Family Applications (2)

Application Number Title Priority Date Filing Date
EP01957164A Ceased EP1301631A4 (en) 2000-07-14 2001-07-16 Novel dna polymerase iii holoenzyme delta subunit nucleic acid molecules and proteins
EP06024949A Withdrawn EP1816213A3 (en) 2000-07-14 2001-07-16 DNA polymerase III holoenzyme delta subunit nucleic acid molecules and proteins

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP06024949A Withdrawn EP1816213A3 (en) 2000-07-14 2001-07-16 DNA polymerase III holoenzyme delta subunit nucleic acid molecules and proteins

Country Status (5)

Country Link
EP (2) EP1301631A4 (en)
JP (1) JP2004508018A (en)
AU (2) AU7893501A (en)
CA (1) CA2416179A1 (en)
WO (1) WO2002006532A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235766A1 (en) * 2001-05-14 2004-11-25 Bullard James M. System for discovery of agents that block yersinia pestis and pseudomonas aeruginosa dna replication
AU2005322593A1 (en) * 2004-04-26 2006-07-06 Replidyne, Inc. Bacterial replication systems and methods
PL245078B1 (en) * 2020-03-17 2024-05-06 Genomtec Spolka Akcyjna Mycoplasma pneumoniae bacteria detection primer kit, Mycoplasma pneumoniae infection detection method, Mycoplasma pneumoniae infection detection primer kit application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668004A (en) * 1992-01-24 1997-09-16 Cornell Research Foundation, Inc. DNA polymerase III holoenzyme from Escherichia coli
WO2001009164A2 (en) * 1999-07-29 2001-02-08 The Rockefeller University Dna replication proteins of gram positive bacteria and their use to screen for chemical inhibitors
WO2001073052A2 (en) * 2000-03-28 2001-10-04 Replidyne, Inc. Thermophilic polymerase iii holoenzyme

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000018958A2 (en) * 1998-09-29 2000-04-06 Government Of The Republic Of Singapore An in vitro activity assay for human hepatits b virus (hbv) dna polymerase, the use of such an assay to assay activity of various serum samples and to screen for inhibitors of the hbv dna polymerase and a method of producing hbv dna polymerase
US20040235766A1 (en) * 2001-05-14 2004-11-25 Bullard James M. System for discovery of agents that block yersinia pestis and pseudomonas aeruginosa dna replication

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668004A (en) * 1992-01-24 1997-09-16 Cornell Research Foundation, Inc. DNA polymerase III holoenzyme from Escherichia coli
WO2001009164A2 (en) * 1999-07-29 2001-02-08 The Rockefeller University Dna replication proteins of gram positive bacteria and their use to screen for chemical inhibitors
WO2001073052A2 (en) * 2000-03-28 2001-10-04 Replidyne, Inc. Thermophilic polymerase iii holoenzyme

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISSPROT [online] 30 May 2000 (2000-05-30), "HYPOTHETICAL PROTEIN AQ_1104", XP002305820, retrieved from NCBI Database accession no. O67189 *
NEUWALD A F ET AL: "AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes.", GENOME RESEARCH. JAN 1999, vol. 9, no. 1, January 1999 (1999-01-01), pages 27 - 43, XP002305819, ISSN: 1088-9051 *
See also references of WO0206532A1 *

Also Published As

Publication number Publication date
CA2416179A1 (en) 2002-01-24
AU2001278935B2 (en) 2007-03-22
WO2002006532A1 (en) 2002-01-24
JP2004508018A (en) 2004-03-18
EP1816213A3 (en) 2007-11-28
EP1816213A2 (en) 2007-08-08
AU7893501A (en) 2002-01-30
EP1301631A1 (en) 2003-04-16

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030212

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: REPLIDYNE, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20050225

17Q First examination report despatched

Effective date: 20050518

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20070128