EP1278762A4 - Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions - Google Patents

Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions

Info

Publication number
EP1278762A4
EP1278762A4 EP01929938A EP01929938A EP1278762A4 EP 1278762 A4 EP1278762 A4 EP 1278762A4 EP 01929938 A EP01929938 A EP 01929938A EP 01929938 A EP01929938 A EP 01929938A EP 1278762 A4 EP1278762 A4 EP 1278762A4
Authority
EP
European Patent Office
Prior art keywords
protein
nucleic acid
acid construct
method utilizing
utilizing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01929938A
Other languages
German (de)
French (fr)
Other versions
EP1278762A2 (en
Inventor
Ami Aronheim
Monika Hubsman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rappaport Family Institute for Research in the Medical Sciences
Original Assignee
Rappaport Family Institute for Research in the Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2000/000247 external-priority patent/WO2000066707A2/en
Priority claimed from US09/777,856 external-priority patent/US20030100022A1/en
Application filed by Rappaport Family Institute for Research in the Medical Sciences filed Critical Rappaport Family Institute for Research in the Medical Sciences
Publication of EP1278762A2 publication Critical patent/EP1278762A2/en
Publication of EP1278762A4 publication Critical patent/EP1278762A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1055Protein x Protein interaction, e.g. two hybrid selection

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP01929938A 2000-05-01 2001-04-30 Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions Withdrawn EP1278762A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US777856 1996-12-31
PCT/IL2000/000247 WO2000066707A2 (en) 1999-05-03 2000-05-01 Novel thiamine transporter, a polynucleotide encoding same and their uses
WOPCT/IL00/00247 2000-05-01
US22015300P 2000-07-24 2000-07-24
US220153P 2000-07-24
US09/777,856 US20030100022A1 (en) 2000-07-24 2001-02-07 Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions
PCT/IL2001/000387 WO2001083808A2 (en) 2000-05-01 2001-04-30 Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions

Publications (2)

Publication Number Publication Date
EP1278762A2 EP1278762A2 (en) 2003-01-29
EP1278762A4 true EP1278762A4 (en) 2003-06-18

Family

ID=27270615

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01929938A Withdrawn EP1278762A4 (en) 2000-05-01 2001-04-30 Nucleic acid construct system and method utilizing same useful for identifying protein-protein interactions

Country Status (3)

Country Link
EP (1) EP1278762A4 (en)
AU (1) AU5661301A (en)
WO (1) WO2001083808A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009002607A1 (en) * 2007-05-01 2008-12-31 Dana-Farber Cancer Institute, Inc. Compositions and methods for identifying transforming and tumor suppressor genes
ATE540115T1 (en) * 2007-07-11 2012-01-15 Yeda Res & Dev NUCLEIC ACID CONSTRUCT SYSTEMS WITH CAPABILITY TO DIAGNOSE OR TREAT A CELL CONDITION

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776689A (en) * 1996-07-19 1998-07-07 The Regents Of The University Of California Protein recruitment system
WO2000066707A2 (en) * 1999-05-03 2000-11-09 Technion Research And Development Foundation Ltd. Novel thiamine transporter, a polynucleotide encoding same and their uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817479A (en) * 1996-08-07 1998-10-06 Incyte Pharmaceuticals, Inc. Human kinase homologs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776689A (en) * 1996-07-19 1998-07-07 The Regents Of The University Of California Protein recruitment system
WO2000066707A2 (en) * 1999-05-03 2000-11-09 Technion Research And Development Foundation Ltd. Novel thiamine transporter, a polynucleotide encoding same and their uses

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ARONHEIM A ET AL: "ISOLATION OF AN AP-1 REPRESSOR BY A NOVEL METHOD FOR DETECTING PROTEIN-PROTEIN INTERACTIONS", MOLECULAR AND CELLULAR BIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, vol. 17, no. 6, June 1997 (1997-06-01), pages 3094 - 3102, XP000867026, ISSN: 0270-7306 *
BRODER Y C ET AL: "THE RAS RECRUITMENT SYSTEM, A NOVEL APPROACH TO THE STUDY OF PROTEIN-PROTEIN INTERACTIONS", CURRENT BIOLOGY, CURRENT SCIENCE,, GB, vol. 8, no. 20, October 1998 (1998-10-01), pages 1121 - 1124, XP000867036, ISSN: 0960-9822 *
HUBSMAN M ET AL: "A novel approach for the identification of protein-protein interaction with integral membrane proteins.", NUCLEIC ACIDS RESEARCH. ENGLAND 15 FEB 2001, vol. 29, no. 4, 15 February 2001 (2001-02-15), pages E18, XP002237898, ISSN: 1362-4962 *
MENDELSOHN A R ET AL: "PROTEIN INTERACTION METHODS-TOWARD AN ENDGAME", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 284, 18 June 1999 (1999-06-18), pages 1948 - 1950, XP001028449, ISSN: 0036-8075 *
See also references of WO0183808A3 *

Also Published As

Publication number Publication date
EP1278762A2 (en) 2003-01-29
AU5661301A (en) 2001-11-12
WO2001083808A3 (en) 2002-03-28
WO2001083808A2 (en) 2001-11-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021114

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20030508

17Q First examination report despatched

Effective date: 20060216

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20081101