EP1278699A4 - Peptides and compounds that bind to the il-5 receptor - Google Patents

Peptides and compounds that bind to the il-5 receptor

Info

Publication number
EP1278699A4
EP1278699A4 EP99965307A EP99965307A EP1278699A4 EP 1278699 A4 EP1278699 A4 EP 1278699A4 EP 99965307 A EP99965307 A EP 99965307A EP 99965307 A EP99965307 A EP 99965307A EP 1278699 A4 EP1278699 A4 EP 1278699A4
Authority
EP
European Patent Office
Prior art keywords
peptides
bind
receptor
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99965307A
Other languages
German (de)
French (fr)
Other versions
EP1278699A1 (en
Inventor
Palani Balu
Qun Yin
Bruce England
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of EP1278699A1 publication Critical patent/EP1278699A1/en
Publication of EP1278699A4 publication Critical patent/EP1278699A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5409—IL-5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP99965307A 1999-12-16 1999-12-16 Peptides and compounds that bind to the il-5 receptor Withdrawn EP1278699A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/030081 WO2001043527A2 (en) 1999-12-16 1999-12-16 Peptides and compounds that bind to the il-5 receptor

Publications (2)

Publication Number Publication Date
EP1278699A1 EP1278699A1 (en) 2003-01-29
EP1278699A4 true EP1278699A4 (en) 2004-10-06

Family

ID=22274327

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99965307A Withdrawn EP1278699A4 (en) 1999-12-16 1999-12-16 Peptides and compounds that bind to the il-5 receptor

Country Status (4)

Country Link
EP (1) EP1278699A4 (en)
AU (1) AU3125500A (en)
CA (1) CA2394323A1 (en)
WO (1) WO2001043527A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100507796B1 (en) * 2003-04-03 2005-08-17 한미약품 주식회사 Peg-biologically active polypeptide homodimer conjugate having enhanced half life in blood and process for the preparation thereof
EP2465873A1 (en) * 2010-12-16 2012-06-20 Deutsches Rheuma-Forschungszentrum Berlin Eosinophils as a therapeutic target

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677280A (en) * 1995-06-07 1997-10-14 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
US5683983A (en) * 1995-06-07 1997-11-04 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
WO1998057991A1 (en) * 1997-06-16 1998-12-23 Glaxo Group Limited Peptides and compounds that bind to the il-5 receptor
WO1998057979A1 (en) * 1997-06-14 1998-12-23 Glaxo Group Limited Peptides and compounds that bind to the il-5 receptor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677280A (en) * 1995-06-07 1997-10-14 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
US5683983A (en) * 1995-06-07 1997-11-04 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
WO1998057979A1 (en) * 1997-06-14 1998-12-23 Glaxo Group Limited Peptides and compounds that bind to the il-5 receptor
WO1998057991A1 (en) * 1997-06-16 1998-12-23 Glaxo Group Limited Peptides and compounds that bind to the il-5 receptor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DEVOS R ET AL: "INTERLEUKIN-5 AND ITS RECEPTOR: A DRUG TARGET FOR EOSINOPHILIA ASSOCIATED WITH CHRONIC ALLERGIC DISEASE", JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL, US, vol. 57, 1 June 1995 (1995-06-01), pages 813 - 819, XP002056891, ISSN: 0741-5400 *
ENGLAND BRUCE P ET AL: "A potent dimeric peptide antagonist of interleukin-5 that binds two interleukin-5 receptor alpha chains", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 97, no. 12, 6 June 2000 (2000-06-06), June 6, 2000, pages 6862 - 6867, XP002277632, ISSN: 0027-8424 *
UINGS IAIN ET AL: "Development of IL-5 receptor antagonists", CURRENT PHARMACEUTICAL DESIGN, vol. 8, no. 20, 2002, pages 1837 - 1844, XP009029675, ISSN: 1381-6128 *
UINGS IAIN J ET AL: "Modified peptide antagonists of interleukin 5 exhibit extended in vivo persistence but restricted species specificity", CYTOKINE, vol. 15, no. 1, 7 July 2001 (2001-07-07), pages 10 - 19, XP002277633, ISSN: 1043-4666 *

Also Published As

Publication number Publication date
CA2394323A1 (en) 2001-06-21
AU3125500A (en) 2001-06-25
WO2001043527A2 (en) 2001-06-21
EP1278699A1 (en) 2003-01-29

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020709

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61P 11/06 B

Ipc: 7A 61K 38/10 B

Ipc: 7C 07K 14/715 B

Ipc: 7C 07K 7/08 A

A4 Supplementary search report drawn up and despatched

Effective date: 20040824

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050701