EP1244993A2 - Large-scale processing loop for implantable medical devices - Google Patents
Large-scale processing loop for implantable medical devicesInfo
- Publication number
- EP1244993A2 EP1244993A2 EP00988167A EP00988167A EP1244993A2 EP 1244993 A2 EP1244993 A2 EP 1244993A2 EP 00988167 A EP00988167 A EP 00988167A EP 00988167 A EP00988167 A EP 00988167A EP 1244993 A2 EP1244993 A2 EP 1244993A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- imd
- network
- patient
- data
- link
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37264—Changing the program; Upgrading firmware
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37282—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by communication with experts in remote locations using a network
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F8/00—Arrangements for software engineering
- G06F8/60—Software deployment
- G06F8/65—Updates
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/40—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
- A61B5/7217—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
Definitions
- the invention generally relates to implantable medical devices (IMDs) Specifically, the invention relates to a large-scale processing loop based on high resolution diagnostic/physiologic data collected by the IMDs More specifically, the data collected by the IMDs is transferred to a remote computation center where evaluation and analysis is performed by high-speed computer resources In the event a change, modification or reprogramming of the LMDs is indicated, the instruction is implemented in the IMDs at the next connection point in time, thus providing continuous momto ⁇ ng to proactively effect changes in the IMDs for efficient therapy and clinical care, in contrast to responding to an adverse patient event or subjecting the patient and clinician to the inconvenience of frequent m-person encounters
- IMD While some data regarding IMD operation may be stored internally to the device, human physiological systems are very complex and nonlinear, I e , exhibiting effects that may appear surprising or chaotic based on predictions using simple periodic or linear models IMDs are designed to dynamically interact with these physiological systems on the fly, but often can only work with simplified models or the most elemental of the systems
- IMDs in interacting with physiological systems are twofold There may be an incomplete understanding of the characteristics of the physiological system in all of its nonlinear complexity However, there may be simply a lack of raw computing power on the part of the IMD Despite the limitations of IMDs with regard to processing power, IMDs are m a unique position to monitor physiological systems continuously High-resolution data can be collected but implantable devices may only store and process limited amounts of complex physiological and medical data
- Prior art methods of clinical services are generally limited to m-hospital procedures or other scenarios involving patient transportation to a clinical setting
- a physician needs to review the performance parameters of an IMD in a patient, it is likely that the patient has to go to the clinic
- the medical conditions of a patient with an IMD warrant a continuous monitoring or adjustment of the device, the patient would have to stay in a hospital indefinitely
- Such a continued treatment plan poses both economic and social problems
- many more hospitals and clinics, and attendant clinicians and service personnel will be needed to provide m-hospital service for the patients, thus escalating the cost of healthcare Additionally, the patients will be unduly restricted and inconvenienced by the need to either stay in the hospital or make very frequent visits to a clinic
- the report contains the identification of all the medical devices involved in any interactive procedure Specifically, all peripheral and major devices that are used in downlinking to the IMD may be reported Currently, such procedures are manually reported, and require an operator or a medical person to manually enter data during each procedure.
- One of the limitations of such manual reporting procedures is the possibility for human error in data entry, thus motivating rechecking of the data to verify accuracy
- the use of human clinicians to analyze data and implement changes in device therapy can result in inefficiencies and errors
- IMDs such as a defib ⁇ llator or a pacer, a neural implant, a drug pump, a separate physiologic monitor and various other IMDs may be implanted in a single patient
- IMDs such as a defib ⁇ llator or a pacer, a neural implant, a drug pump, a separate physiologic monitor and various other IMDs
- To successfully manage the operations and assess the performance of each device in a patient with multi-implants requires a continuous update and monitoring of the devices
- there is a need to monitor the IMDs and the programmer on a regular, if not a continuous, basis to ensure optimal patient care In the absence of other alternatives, this imposes a great burden on the patient if a hospital or clinic is the only center where the necessary upgrade follow up, evaluation and adjustment of the IMDs could be made Further, even if feasible, the situation would require the establishment of multiple service
- IMDs of the prior art are limited in that the features and functions of implantable medical device mav not take full advantage of the complex modeling of physiologic systems that are being continually established, these devices simply lack the processing power to perform the required calculations, and may be expected to lack this power indefinitely Accordingly, civilization's ever-increasing knowledge of physiologic systems must be simplified considerably in order to be implemented within an IMD It would be desirable to provide a system by which the complex modeling of physiologic systems could be brought to bear in IMD instruction in order to improve patient outcomes
- This invention proposes to link the power of the external computing world to the implantable medical device via a network of commumcations devices
- a technology-based health care system that fully integrates the technical and social aspects of patient care and therapy will preferably flawlessly connect the client with care providers irrespective of separation distance or location of the participants
- a programmer unit that would connect to a centralized data source and repository
- This remote data center will preferably provide access to an expert system allowing for downloading of upgrade data or other information to a local environment
- it is important to have a large scale processing loop to enable the gathering of high resolution diagnostic/physiologic data, and to transfer information between the IMDs and a remote expert data center to dispense therapy and clinical care on real-time basis
- the large-scale processing loop contemplated bv the present invention enables an efficient system for data storage, collection and processing to effect changes in control algorithms of the IMDs and associated medical units to promote real time therapy and clinical care
- one or more IMDs such as a pacemaker defib ⁇ llator, drug pump, neurological stimulator, physiological signal recorder may be deployed in a patient
- This IMD may be equipped with a radio frequency transmitter or receiver, or an alternate wireless communication telemetry technique or media which may travel through human tissue
- the IMD may contain a transmission device capable of transmitting through human tissue such as radio frequency telemetry, acoustic telemetry, or a transmission technique that uses patient tissue as a transmission medium
- an IMD may be deployed in a fashion by which a transmission or receiving device is
- the amount of historical data, particularly patient-specific historical data used as input to control systems can be virtually unlimited when it is stored externally to the patient
- a more thorough comparison can be made between patients with similar diseases as data and therapy information, procedure and direction are centralized which mav be expected to result in gains to the body of medical knowledge and treatment efficacy
- Data from other medical systems either implanted or external, such as etiological databases can be incorporated easily into the control system
- Other anonymous patient experiences or treatment data may be more quickly incorporated into a subject patient's IMD regime than might be possible with existing systems of IMD programming or upgrading
- a subject patient's own historical treatment parameters and corresponding outcomes mav be used in making IMD programming and other treatment decisions
- the instant invention provides IMDs with access to virtually unlimited computing power as part of their data collection and therapy calculation processes
- the IMD may be used by an external computing device as a data collection agent, and as an agent to implement changes to a treatment regimen based on a complex dynamical or
- a communications system provides the ability to have high-power computing systems interact with implanted medical devices, thus providing the ability to use complex control algorithms and models in implanted medical devices.
- implanted medical devices thus providing the ability to use complex control algorithms and models in implanted medical devices.
- relatively simple modeling, or in stochastic models relatively large amounts of historical data from a single or multiple medical devices may be brought to bear for predictive purposes in evaluating alternate therapy and IMD instruction prescriptions
- the present invention provides a system that establishes an external communications device and data network as a 'data bus' for extending the processing power of deployed IMDs, while minimizing host patient and clinician inconvenience
- Figure 1 depicts a general network architecture diagram of system embodying the subject invention
- Figure 2 depicts the system of Figure 1 including specific functional modules within the components of the system
- FIG. 3 depicts an alternate embodiment of the system depicted in Figure 2 DETAILED DESCRIPTION OF THE DRAWINGS
- Figure 1 depicts a general architectural view of a large-scale processing network according to an embodiment of the present invention
- An IMD programming and instruction system 1 10 is provided IMD 1 12 has been deployed in a patient 1 14, for example, a patient at a location remote from large-scale processor 1 16
- the IMD mav be one of a number of existing or to be developed IMDs, for example, a pacemaker, defib ⁇ llator, drug pump, neurological stimulator, physiological signal recorder, oxygen sensor, or the like
- a single IMD 1 12 is depicted, the subject invention permits of use with multiple IMDs deployed in a single patient, each making separate transmissions and receiving separate instructions from routing instrument 1 18
- multiple IMDs deployed in a single patient are all linked to a single telemetry device implanted in a patient This telemetry device may be separate from or incorporated into one of the I
- IMD 1 12 is equipped with or linked to a transmission and receiving device such as a radio frequency telemetry device 120, also implanted in patient 1 14
- a transmission and receiving device such as a radio frequency telemetry device 120
- an external device is provided which may be termed a routing instrument
- This routing instrument 1 18 may communicate with the IMD via radio frequency, as discussed above
- the routing device 1 18 may also communicate with a data network via modem, LAN, WAN, wireless or infrared means
- This data network 120 is preferably able to communicate via a computer network or other suitable data communications connection with a central computer 1 16 capable of carrying out large scale or parallel processing of patient data from one or more patients having deployed IMDs
- the large-scale computing center or central computer 1 16 preferably has sufficient computing power and storage capability to collect and process large amounts of physiological data using complex control systems
- the patient is placed or places himself or herself in proximity to routing instrument 1 18
- routing instrument 1 18 may be placed in a patient's home at their bedside perhaps, or may be
- routing instrument 1 18 contains a radio frequency transmitter/receiver or similar radio frequency telemetry device
- routing instrument 1 18 may communicate with central large-scale computer 1 16 via a number of network schemes or connections, with regard to any of the OSI layers
- communication mav be effected bv way of a TCP/IP connection, particularly one using the Internet, as well as a LAN, WAN, MAN, direct dial-up connection, a dedicated line, or a dedicated terminal connection to a mainframe
- Large-scale computer 1 16 will preferably possess appreciably more computing power than possible with an IMD in terms of processor speed, RAM available, and data storage While computer 1 16 is referred to a large-scale, it is large scale only relative to such processors that are available for incorporation into an IMD For example, some commercially-available personal computers may contain sufficient computing power to operate as a server capable of carrying out many IMD diagnostic and programming tasks
- large-scale computer 1 16 will be a mainframe, multi-processor supercomputer, or a multi-processor workstation, such as a type available from Silicon Graphics, Inc /SGI of Mountain View, California
- Such relatively high-powered computing devices are better suited to calculations involving nonlinear systems and models such as those being developed to model physiologic systems
- the computing device will be configured as a server capable of communicating directly or indirectly with routing instrument 1 18
- the computer 1 16 will preferably have sufficient storage, either internal to the computer or linked to the computer, for the storage of massive amounts of historical patient data from, for example, a particular patient having an
- IMD in communication with computer 1 16, and/or subject data from relevant physiologic studies or from cohort groups having similar medical conditions and/or deployed IMDs
- Security and integrity of the patient information will preferably be closely guarded for at least the following reasons
- patient physiologic data detected by a deployed IMD will be transmitted via routing instrument 1 18 to computer 1 16 for purposes of analysis of this data, and treatment regimens and/or IMD instructions, firmware, or software may be changed on the basis of this information
- integrity of transmitted data and instructions will preferably be maintained so as to avoid adverse patient outcomes or patient outcomes that do not take full advantage of the subject invention
- patient information that may be linked to an identifiable individual is typically regarded as confidential
- encryption will preferably be provided to ensure patient confidentiality, particularly when transmissions between routing instrument 1 18 and computer 1 16 takes place though media other than a dedicated line/direct dial-up connection, such as a packet based network technology over a public network or internetwork
- TCP/IP encryption will preferably be used as an alternative to
- a preferred embodiment of the subject invention utilizes digital signatures and encryption of the patient information and IMD instructions being transmitted according to the present invention
- Encryption of patient information will serve to protect patient confidentiality
- Each transmission of patient data will preferably have a digital signature that can be checked against the transmission payload to ensure that patient data and IMD instructions were not corrupted during transmission
- Examples of encryption/digital signature schemes that should prove sufficient Encryption of patient information and digital signatures include PGP, the RSA public key infrastructure scheme, or other consumer-level or higher, prime number based encryption signature scheme
- Transmissions between an IMD 1 12 and a routing device 1 18 will also preferably be protected from transmission errors using similar encryption, authentication, and verification techmques, and/or wireless communication enhancement techniques such as wireless modulation or another suitable wide-frequency spectra technique
- encryption and/or authentication will be effected end-to-end, I e , covering the entire transmission from IMD 1 12 to computer 1 16 or from computer 1 16 to IMD 1 12, rather than effecting one encryption/verification scheme between IMD 1 12 and routing instrument 1 18, and a different scheme from routing instrument 1 18 and computer 1 16
- radio frequency pulse coding, spread spectrum, direct sequence time-hopping, frequency hopping, a hybrid spread spectrum technique, or other wireless modulation techniques may be employed in order to reduce interference between IMD 1 12 and other IMD or other wireless devices, and to generally offer improved accuracy, reliability, and security to transmissions between IMD 1 12 and routing instrument 1 18, mav be used to avoid cross-talk or confusion among IMDs and/or routing instruments in proximity to
- the deployed IMD collects physiological data from the host patient via electrical, mechanical or chemical sensors, according to the type of IMD deployed in the host patient Some of this data may be used locally, I e , processed and analyzed internally to the IMD itself, to modify therapy or treatment on a 'real-time' basis Regardless of whether the physiological data from the host patient is used to modify therapy on this self- contained basis, the patient data will preferably be buffered in the IMD until such time as the device is polled or interrogated" by routing instrument 1 18 This interrogation may take place in accordance with co-pending application of the common assignee, entitled
- the routing instrument 1 18 may also pass instructions received from the computing center to the IMD
- Routing instrument 1 18 may contact the computing center or central large-scale processor 1 16 and transmit the physiologic data uploaded from IMD 1 12 to routing instrument 1 18
- the powerful computer(s) at the computing center 1 16 may store and/or process the data, perhaps combining it with historical data of the same type from the same device, or perhaps with data from other implanted and medical devices
- the physiologic data may be combined with anonymous data from other demographic or clinical groups consisting of subjects which may have data relevant or genera zable to host patient 1 14
- comparisons of the data collected mav be made with data from other patients with similar disease states, and therapy solutions constructed and compared
- the computing center may then transfer instructions on modifications to therapy and data collection to the routing device 1 18
- the routing device transfers the instructions to the IMD and may also collect an additional batch of data buffered in the IMD
- This opportunity for communication between routing device 1 18 and IMD 1 12 may not be immediately present
- host patient 1 14 mav be located away from routing instrument temporarily if the host patient has left their house or clinical setting where the
- Data may also be held at central computing center 1 16, for example, if the routing device 1 18 is carried by host patient 1 14 as a portable device, and an analog connection for a modem or suitable network connection may not be available
- communication system 1 10 will operate asynchronously, permitting for the possibility for breaks in the continuous and realtime communications and/or processing of the three subsystems (IMD 1 12, routing instrument 1 18, and large scale computer 1 16
- IMD 1 12, routing instrument 1 18, and large scale computer 1 16 alternate embodiments of the invention are also possible, including synchronous, "real-time' control of the target IMD 1 12
- This alternate "real-time" embodiment of the system 1 10 may be enhanced upon the establishment of more ubiquitous and robust communications systems or links
- IMD 1 12 effects the collection of high resolution physiological data, and provides for its temporary storage or buffering, for example in storage device 210
- This storage device is preferably a RAM module of a type suitable for implementation in IMDs
- IMD processor 212 will preferably compress the physiologic data collected by physiologic sensor 214
- IMD processor 212 in addition to processing the reception and storage of physiologic data, also preferably effects implementation of IMD therapy
- processor 212 may control the amount or frequency of electrical stimuli or drug delivered by IMD 1 12 This control will preferably be based on instructions originating from central computer 1 16, after processing of relevant historical or patient cohort data and determination of a suitable treatment regimen that may be effected by IMD 1 12
- Figure 2 also depicts in greater detail the architecture of routing instrument 1 18 of Figure 1 As shown in Figure 2, routing instrument 1 18 contains a transmitter/receiver
- routing instrument 1 18 contains architecture components similar to those seen in a computer
- Figure 3 depicts the communication system 1 10 of Figures 1 and 2 with routing instrument 1 18 implemented as a computer 310 with a peripheral device 314 that may communicate with IMD 1 12
- communications between routing instrument 1 18 and computing center 1 16 may be effected either through a network 230, such as a LAN or the Internet, or communications may be effected through a direct dial-up or dedicated line, or through a terminal connection to a mainframe
- communications link 232 Typically, these connections may be considered alternatives, or both communications links, l e , relatively direct link 232 and link through network 230 may be implemented in order to provide a backup commumcations system to the link used as the primary communication method
- Routing instrument 1 18 Upon establishing contact with routing instrument 1 18, an IMD instruction regimen may be pushed or generally transmitted to routing instrument 1 18, or computer 310 in Figure 3 implementing the routing function Routing instrument 1 18 or equivalent then stores the results of processing or analysis carried out by large-scale computer 1 16 The
- IMD instruction regimen prescribed by central computer 1 16 may be stored within routing device 1 18 indefinitely or for a fixed period of time prior to expiration At the next opportunity for communication between routing device 1 18 and IMD 1 12, routing instrument provides new therapy programming, as well as new instructions for data collection if necessary
- routing device 1 18 if an instruction regimen has been received by routing device 1 18 for communication to target IMD 1 12, routing device 1 18 will periodically poll IMD 1 12 m attempts to establish a communication link, such as a wireless link
- routing device 1 18 may have a display feature, which could be for example an LCD display or a simple indicator light indicating that an instruction regimen has been received for forwarding from central computer 1 16
- a human user for example, host patient 1 14 of
- Figure 1 may press a button or otherwise initiate the process of communication between routing device 1 18 and target IMD 1 12 If routing device 1 18 is implemented on a computer such as a PC 310 of Figure 3 with a transmitter/receiver peripheral device, a suitable pop-up message on PC monitor 312 may indicate a pending IMD instruction or request, or an indicator on a display of peripheral transmitter/receiver 314 may indicate a pending instruction as above
- routing device may send an error message identifying the IMD and/or instruction regimen by a suitable code
- central computer 1 16 may be programmed to carry out suitable updating of an instruction regimen, or an error message may be output to a human operator or clinician for direct intervention by voice telephony or direct contact by mobile clinical personnel, for example
- routing device 1 18 is portrayed in Figure 2 as a self-contained or stand-alone umt, it will be appreciated that routing device 1 18 may also be implemented, as depicted in
- FIG 3 as a peripheral transmitter receiver capable of wireless communication with IMD 1 12, and also in communication with computer 310, such as a personal computer such as a laptop or portable computer
- Computer 310 may also be a terminal of a remote mainframe computer 1 16, at which large-scale computing tasks may be carried out
- routing instrument 1 18 is implemented as a peripheral and mainframe terminal, some of the components of routing device 1 18, such as storage device 224, may be implemented on a mainframe computer 1 16 rather than in the terminal implementing routing device 1 18
- transmitter/ receiver 3 14 serves merely as a communication interface between IMD 1 12 and routing computer 3 10
- the functions of routing instrument 1 18 of Figure 2 may be implemented in software resident on routing computer 310
- Communications interfaces of routing computer 3 10 may include a modem, network card, direct connection, or terminal connection
- a IMD-local computer 3 10 carries out communication with large scale computer or mainframe 1 16 preferably all data communication security and message
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- Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Business, Economics & Management (AREA)
- General Business, Economics & Management (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Software Systems (AREA)
- Theoretical Computer Science (AREA)
- Databases & Information Systems (AREA)
- Pathology (AREA)
- Computer Security & Cryptography (AREA)
- Data Mining & Analysis (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
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- Electrotherapy Devices (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17307999P | 1999-12-24 | 1999-12-24 | |
US173079P | 1999-12-24 | ||
PCT/US2000/034520 WO2001048675A2 (en) | 1999-12-24 | 2000-12-19 | Large-scale processing loop for implantable medical devices |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1244993A2 true EP1244993A2 (en) | 2002-10-02 |
Family
ID=22630450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00988167A Ceased EP1244993A2 (en) | 1999-12-24 | 2000-12-19 | Large-scale processing loop for implantable medical devices |
Country Status (2)
Country | Link |
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EP (1) | EP1244993A2 (en) |
WO (1) | WO2001048675A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7103578B2 (en) | 2001-05-25 | 2006-09-05 | Roche Diagnostics Operations, Inc. | Remote medical device access |
SE0102918D0 (en) | 2001-08-30 | 2001-08-30 | St Jude Medical | Method of providing software to an implantable medical device system |
US20050222631A1 (en) * | 2004-04-06 | 2005-10-06 | Nirav Dalal | Hierarchical data storage and analysis system for implantable medical devices |
US8176922B2 (en) | 2004-06-29 | 2012-05-15 | Depuy Products, Inc. | System and method for bidirectional communication with an implantable medical device using an implant component as an antenna |
US8001975B2 (en) | 2004-12-29 | 2011-08-23 | Depuy Products, Inc. | Medical device communications network |
EP1895437A1 (en) * | 2006-09-01 | 2008-03-05 | F.Hoffmann-La Roche Ag | Medical infusion devices and method for administrating such devices |
US8080064B2 (en) | 2007-06-29 | 2011-12-20 | Depuy Products, Inc. | Tibial tray assembly having a wireless communication device |
EP3623953B1 (en) * | 2018-09-17 | 2022-01-19 | Siemens Healthcare GmbH | Technical improvement evaluation for a set of applications |
CN113590499B (en) * | 2020-04-30 | 2024-07-12 | 深圳市帝迈生物技术有限公司 | Blood analyzer, data processing method thereof and computer storage medium |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5353793A (en) * | 1991-11-25 | 1994-10-11 | Oishi-Kogyo Company | Sensor apparatus |
KR100197580B1 (en) * | 1995-09-13 | 1999-06-15 | 이민화 | A living body monitoring system making use of wireless netwokk |
US5720770A (en) * | 1995-10-06 | 1998-02-24 | Pacesetter, Inc. | Cardiac stimulation system with enhanced communication and control capability |
-
2000
- 2000-12-19 WO PCT/US2000/034520 patent/WO2001048675A2/en active Application Filing
- 2000-12-19 EP EP00988167A patent/EP1244993A2/en not_active Ceased
Non-Patent Citations (1)
Title |
---|
See references of WO0148675A2 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001048675A3 (en) | 2002-05-30 |
WO2001048675A2 (en) | 2001-07-05 |
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