EP1240178A4 - Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides - Google Patents

Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides

Info

Publication number
EP1240178A4
EP1240178A4 EP00989432A EP00989432A EP1240178A4 EP 1240178 A4 EP1240178 A4 EP 1240178A4 EP 00989432 A EP00989432 A EP 00989432A EP 00989432 A EP00989432 A EP 00989432A EP 1240178 A4 EP1240178 A4 EP 1240178A4
Authority
EP
European Patent Office
Prior art keywords
prothrombinase
polynucleotides
polypeptides
methods
materials relating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00989432A
Other languages
German (de)
English (en)
Other versions
EP1240178A2 (fr
Inventor
Dana A Haley
Bryan J Boyle
Ho Alice Suk-Yue
Ping Zhou
Nancy K Mize
Chiauyun Kuo
Matthew C Arterburn
Y Tom Tang
Chenghua Liu
Radoje Drmanac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/596,196 external-priority patent/US6586390B1/en
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Publication of EP1240178A2 publication Critical patent/EP1240178A2/fr
Publication of EP1240178A4 publication Critical patent/EP1240178A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
EP00989432A 1999-12-23 2000-12-22 Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides Withdrawn EP1240178A4 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US47127599A 1999-12-23 1999-12-23
US471275 1999-12-23
US48872500A 2000-01-21 2000-01-21
US488725 2000-01-21
US49140400A 2000-01-25 2000-01-25
US491404 2000-01-25
US55231700A 2000-04-25 2000-04-25
US552317 2000-04-25
US09/596,196 US6586390B1 (en) 2000-01-21 2000-06-17 Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides
US596196 2000-06-17
US64331300A 2000-08-31 2000-08-31
US643313 2000-08-31
PCT/US2000/035061 WO2001053456A2 (fr) 1999-12-23 2000-12-22 Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides

Publications (2)

Publication Number Publication Date
EP1240178A2 EP1240178A2 (fr) 2002-09-18
EP1240178A4 true EP1240178A4 (fr) 2004-06-30

Family

ID=27560029

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00989432A Withdrawn EP1240178A4 (fr) 1999-12-23 2000-12-22 Procedes et substances relatifs a des polypeptides de type prothrombinase et a des polynucleotides

Country Status (4)

Country Link
EP (1) EP1240178A4 (fr)
AU (1) AU783762B2 (fr)
CA (1) CA2395749A1 (fr)
WO (1) WO2001053456A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002224056A1 (en) * 2000-11-22 2002-06-03 Yamanouchi Pharmaceutical Co..Ltd. Novel polypeptide
CA2399569A1 (fr) 2001-09-25 2003-03-25 Yusuke Nakamura Marqueurs diagnostiques et cibles therapeutiques pour le traitement du cancer
EP1430152B1 (fr) 2001-09-25 2007-03-07 Japan as represented by The President of the University of Tokyo Gene et proteine lies au carcinome hepatocellulaire
EP1575497A4 (fr) * 2002-09-11 2010-11-03 Genentech Inc Nouvelle composition et nouveaux procedes pour le traitement du psoriasis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005825A2 (fr) * 1999-07-16 2001-01-25 Hyseq, Inc. Nouveaux procedes et materiaux des angiopoietines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005825A2 (fr) * 1999-07-16 2001-01-25 Hyseq, Inc. Nouveaux procedes et materiaux des angiopoietines

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI; 17 November 1999 (1999-11-17), BIRREN B. ET AL.: "Homo sapiens clone RP-11-21G19, WORKING DRAFT SEQUENCE, 11 unordered pieces.", XP002275729, Database accession no. AC015500 *
DATABASE EMBL [online] EBI; 3 September 1994 (1994-09-03), RUEGG C.: "H. sapiens mRNA for fibrinogen-like protein (pT49 protein).", XP002275808, Database accession no. Z36531 *
KIM I ET AL: "Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3.", FEBS LETTERS. NETHERLANDS 29 JAN 1999, vol. 443, no. 3, 29 January 1999 (1999-01-29), pages 353 - 356, XP004259174, ISSN: 0014-5793 *
MARAZZI S ET AL: "Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD.: 1950) UNITED STATES 1 JUL 1998, vol. 161, no. 1, Z36531, 1 July 1998 (1998-07-01), pages 138 - 147, XP002254978, ISSN: 0022-1767 *
See also references of WO0153456A3 *
YUWARAJ S ET AL: "Genomic characterization, localization, and functional expression of FGL2, the human gene encoding fibroleukin: a novel human procoagulant.", GENOMICS. UNITED STATES 1 FEB 2001, vol. 71, no. 3, 1 February 2001 (2001-02-01), pages 330 - 338, XP004432297, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
WO2001053456A9 (fr) 2002-12-05
WO2001053456A8 (fr) 2002-07-04
WO2001053456A2 (fr) 2001-07-26
AU783762B2 (en) 2005-12-01
AU2593601A (en) 2001-07-31
EP1240178A2 (fr) 2002-09-18
CA2395749A1 (fr) 2001-07-26
WO2001053456A3 (fr) 2002-05-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20020624

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHOU, PING

Inventor name: KUO, CHIAUYUN

Inventor name: SUK-YUE HO, ALICE

Inventor name: TANG, Y., TOM

Inventor name: BOYLE, BRYAN, J.

Inventor name: ARTERBURN, MATTHEW, C.

Inventor name: HALEY, DANA, A.

Inventor name: MIZE, NANCY, K.

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NUVELO INC.

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NUVELO, INC.

RTI1 Title (correction)

Free format text: METHODS AND MATERIALS RELATING TO PROTHROMBINASE-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES.

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/475 B

Ipc: 7C 07K 14/705 A

A4 Supplementary search report drawn up and despatched

Effective date: 20040513

17Q First examination report despatched

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