EP1235841A4 - Declenchement de reponses immunitaires cellulaires a mage2/3 au moyen de compositions de peptides et d'acides nucleiques - Google Patents
Declenchement de reponses immunitaires cellulaires a mage2/3 au moyen de compositions de peptides et d'acides nucleiquesInfo
- Publication number
- EP1235841A4 EP1235841A4 EP00984183A EP00984183A EP1235841A4 EP 1235841 A4 EP1235841 A4 EP 1235841A4 EP 00984183 A EP00984183 A EP 00984183A EP 00984183 A EP00984183 A EP 00984183A EP 1235841 A4 EP1235841 A4 EP 1235841A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- mage2
- peptide
- nucleic acid
- immune responses
- cellular immune
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000024932 T cell mediated immunity Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001186—MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464484—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/464486—MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45829899A | 1999-12-10 | 1999-12-10 | |
US458298 | 1999-12-10 | ||
PCT/US2000/033545 WO2001042267A1 (fr) | 1999-12-10 | 2000-12-11 | Declenchement de reponses immunitaires cellulaires a mage2/3 au moyen de compositions de peptides et d'acides nucleiques |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1235841A1 EP1235841A1 (fr) | 2002-09-04 |
EP1235841A4 true EP1235841A4 (fr) | 2006-04-12 |
Family
ID=23820224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00984183A Withdrawn EP1235841A4 (fr) | 1999-12-10 | 2000-12-11 | Declenchement de reponses immunitaires cellulaires a mage2/3 au moyen de compositions de peptides et d'acides nucleiques |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1235841A4 (fr) |
JP (1) | JP2003517310A (fr) |
AU (1) | AU2085001A (fr) |
CA (1) | CA2393339A1 (fr) |
WO (1) | WO2001042267A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060222656A1 (en) | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
AU2002322009A1 (en) | 2001-05-18 | 2002-12-03 | Mayo Foundation For Medical Education And Research | Chimeric antigen-specific t cell-activating polypeptides |
FR2837837B1 (fr) * | 2002-03-28 | 2006-09-29 | Roussy Inst Gustave | Epitopes peptidiques communs a des antigenes d'une meme famille multigenique |
US7488793B2 (en) * | 2003-09-22 | 2009-02-10 | Ludwig Institute For Cancer Research | Isolated peptide which binds to HLA-Cw*07 and uses thereof |
EP2391635B1 (fr) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Polypeptides de liaison de pan-dr et leurs utilisations |
ES2533228T3 (es) * | 2009-06-09 | 2015-04-08 | Vaxon Biotech | Identificación, optimización y uso de epítopos compartidos de HLA-B*0702 para inmunoterapia |
JP6255360B2 (ja) * | 2015-03-04 | 2017-12-27 | ヴァクソン バイオテックVaxon Biotech | 共有hla−b*0702エピトープの同定、最適化および免疫療法のための使用 |
MY193703A (en) * | 2015-03-27 | 2022-10-26 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various tumors |
GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
WO2020048990A1 (fr) * | 2018-09-04 | 2020-03-12 | Treos Bio Zrt | Vaccins peptidiques |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995022317A1 (fr) * | 1994-02-16 | 1995-08-24 | Cytel Corporation | Compositions et procedes utilises pour induire une immunite par les lymphocytes t cytotoxiques |
WO1997013858A2 (fr) * | 1995-10-12 | 1997-04-17 | Chiron Corporation | Homologues de mage-3 du babouin, adn codant pour ceux-ci et technique d'utilisation associee |
US5662907A (en) * | 1992-08-07 | 1997-09-02 | Cytel Corporation | Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes |
WO1999045954A1 (fr) * | 1998-03-13 | 1999-09-16 | Epimmune, Inc. | Peptides de liaison de hla et leurs applications |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0721341A4 (fr) * | 1993-08-06 | 1998-04-22 | Cytel Corp | Clonage et description des caracteristiques du gene mage-1 complet |
US5965535A (en) * | 1997-09-12 | 1999-10-12 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
US5965381A (en) * | 1998-03-06 | 1999-10-12 | Ludwig Institute For Cancer Research | Delivery of proteins into eukaryotic cells with recombinant yersinia |
-
2000
- 2000-12-11 EP EP00984183A patent/EP1235841A4/fr not_active Withdrawn
- 2000-12-11 WO PCT/US2000/033545 patent/WO2001042267A1/fr not_active Application Discontinuation
- 2000-12-11 CA CA002393339A patent/CA2393339A1/fr not_active Abandoned
- 2000-12-11 JP JP2001543564A patent/JP2003517310A/ja not_active Withdrawn
- 2000-12-11 AU AU20850/01A patent/AU2085001A/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5662907A (en) * | 1992-08-07 | 1997-09-02 | Cytel Corporation | Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes |
WO1995022317A1 (fr) * | 1994-02-16 | 1995-08-24 | Cytel Corporation | Compositions et procedes utilises pour induire une immunite par les lymphocytes t cytotoxiques |
WO1997013858A2 (fr) * | 1995-10-12 | 1997-04-17 | Chiron Corporation | Homologues de mage-3 du babouin, adn codant pour ceux-ci et technique d'utilisation associee |
WO1999045954A1 (fr) * | 1998-03-13 | 1999-09-16 | Epimmune, Inc. | Peptides de liaison de hla et leurs applications |
Non-Patent Citations (3)
Title |
---|
ALTMAN J ET AL: "Phenotypic analysis of antigen-specific T lymphocytes", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 274, no. 5284, 4 October 1996 (1996-10-04), pages 94 - 96, XP002135711, ISSN: 0036-8075 * |
DEL GUERCIO M-F ET AL: "Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T Helper Epitopes (PADRE) for antibody responses in vivo", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 15, no. 4, March 1997 (1997-03-01), pages 441 - 448, XP004094438, ISSN: 0264-410X * |
See also references of WO0142267A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003517310A (ja) | 2003-05-27 |
CA2393339A1 (fr) | 2001-06-14 |
EP1235841A1 (fr) | 2002-09-04 |
WO2001042267A1 (fr) | 2001-06-14 |
AU2085001A (en) | 2001-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020621 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SOUTHWOOD, SCOTT Inventor name: CHESNUT, ROBERT Inventor name: CELIS, ESTEBAN Inventor name: FIKES, JOHN Inventor name: KEOGH, ELISSA Inventor name: SETTE, ALESSANDRO Inventor name: SIDNEY, JOHN |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060227 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20061017 |