EP1235791A4 - A multistage process for the preparation of highly pure deferoxamine mesylate salt - Google Patents

A multistage process for the preparation of highly pure deferoxamine mesylate salt

Info

Publication number
EP1235791A4
EP1235791A4 EP00982299A EP00982299A EP1235791A4 EP 1235791 A4 EP1235791 A4 EP 1235791A4 EP 00982299 A EP00982299 A EP 00982299A EP 00982299 A EP00982299 A EP 00982299A EP 1235791 A4 EP1235791 A4 EP 1235791A4
Authority
EP
European Patent Office
Prior art keywords
preparation
highly pure
mesylate salt
multistage process
deferoxamine mesylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00982299A
Other languages
German (de)
French (fr)
Other versions
EP1235791A1 (en
Inventor
Vilmos Keri
Zoltan Czovek
Attila Mezo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Teva Pharmaceutical Works PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Works PLC filed Critical Teva Pharmaceutical Works PLC
Publication of EP1235791A1 publication Critical patent/EP1235791A1/en
Publication of EP1235791A4 publication Critical patent/EP1235791A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP00982299A 1999-12-01 2000-11-30 A multistage process for the preparation of highly pure deferoxamine mesylate salt Withdrawn EP1235791A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9904454P 1999-12-01
HU9904454A HU227315B1 (en) 1999-12-01 1999-12-01 Process having several steps for producing deferoxamine mesilate of high purity
PCT/US2000/032574 WO2001040164A1 (en) 1999-12-01 2000-11-30 A multistage process for the preparation of highly pure deferoxamine mesylate salt

Publications (2)

Publication Number Publication Date
EP1235791A1 EP1235791A1 (en) 2002-09-04
EP1235791A4 true EP1235791A4 (en) 2006-03-08

Family

ID=90000087

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00982299A Withdrawn EP1235791A4 (en) 1999-12-01 2000-11-30 A multistage process for the preparation of highly pure deferoxamine mesylate salt

Country Status (15)

Country Link
EP (1) EP1235791A4 (en)
JP (1) JP2003515579A (en)
KR (1) KR20020067044A (en)
CN (1) CN1433399A (en)
AU (1) AU1935101A (en)
CA (1) CA2392925A1 (en)
CZ (1) CZ20021823A3 (en)
HU (1) HU227315B1 (en)
MX (1) MXPA02005377A (en)
PL (1) PL355328A1 (en)
RU (1) RU2002114073A (en)
SK (1) SK7472002A3 (en)
WO (1) WO2001040164A1 (en)
YU (1) YU39602A (en)
ZA (1) ZA200204030B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111544374A (en) * 2020-05-13 2020-08-18 中国人民解放军总医院第四医学中心 Application of deferoxamine mesylate for injection in treating age-increasing bone loss and bone marrow stem cell senescence

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1898M (en) * 1961-04-07 1963-07-08 Ciba Geigy New substance usable in therapy.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH438351A (en) * 1959-09-25 1967-06-30 Ciba Geigy Process for the production of new growth substances
WO1993003045A1 (en) * 1991-08-09 1993-02-18 The Regents Of The University Of California Process for purer organic metal ion chelate complexes
US5254724A (en) * 1991-10-30 1993-10-19 University Of Florida Research Foundation, Inc. Method for synthesis of desferrioxamine B, analogs and homologs thereof
HU214452B (en) * 1992-06-01 1998-03-30 BIOGAL Gyógyszergyár Rt. Process for producing salts of deferoxamin b with high purity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1898M (en) * 1961-04-07 1963-07-08 Ciba Geigy New substance usable in therapy.

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BICKEL H ET AL: "STOFFWECHSELPRODUKTE VON MIKROORGANISMEN ZUR KENNTNIS VON DESFERRIOXAMIN B", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 46, no. 4, 1963, pages 1385 - 1389, XP002049220, ISSN: 0018-019X *
See also references of WO0140164A1 *

Also Published As

Publication number Publication date
SK7472002A3 (en) 2003-03-04
WO2001040164A1 (en) 2001-06-07
CN1433399A (en) 2003-07-30
KR20020067044A (en) 2002-08-21
AU1935101A (en) 2001-06-12
JP2003515579A (en) 2003-05-07
PL355328A1 (en) 2004-04-19
MXPA02005377A (en) 2002-12-05
HUP9904454A2 (en) 2001-08-28
YU39602A (en) 2005-07-19
HU9904454D0 (en) 2000-02-28
RU2002114073A (en) 2004-01-20
HU227315B1 (en) 2011-03-28
CZ20021823A3 (en) 2003-02-12
EP1235791A1 (en) 2002-09-04
CA2392925A1 (en) 2001-06-07
ZA200204030B (en) 2003-05-21

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Legal Events

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