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Fibrin sealant as a transfection/transformation vehicle for gene therapy

Info

Publication number
EP1208212A4
EP1208212A4 EP19990935322 EP99935322A EP1208212A4 EP 1208212 A4 EP1208212 A4 EP 1208212A4 EP 19990935322 EP19990935322 EP 19990935322 EP 99935322 A EP99935322 A EP 99935322A EP 1208212 A4 EP1208212 A4 EP 1208212A4
Authority
EP
Grant status
Application
Patent type
Prior art keywords
fibrin
sealant
therapy
transfection
transformation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19990935322
Other languages
German (de)
French (fr)
Other versions
EP1208212A1 (en )
Inventor
Stewart A Cederholm-Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIVOLUTION A/S
Original Assignee
Bristol-Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
EP19990935322 1999-06-16 1999-06-16 Fibrin sealant as a transfection/transformation vehicle for gene therapy Withdrawn EP1208212A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US1999/013508 WO2000077227A1 (en) 1999-06-16 1999-06-16 Fibrin sealant as a transfection/transformation vehicle for gene therapy

Publications (2)

Publication Number Publication Date
EP1208212A1 true EP1208212A1 (en) 2002-05-29
EP1208212A4 true true EP1208212A4 (en) 2007-05-02

Family

ID=22272977

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19990935322 Withdrawn EP1208212A4 (en) 1999-06-16 1999-06-16 Fibrin sealant as a transfection/transformation vehicle for gene therapy

Country Status (4)

Country Link
JP (1) JP2003502047A (en)
CA (1) CA2375346A1 (en)
EP (1) EP1208212A4 (en)
WO (1) WO2000077227A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0423681D0 (en) * 2004-10-26 2004-11-24 Sec Dep For Environment Food & Vaccine and nucleic acids
CN102089322B (en) 2008-07-09 2015-09-23 普罗菲布瑞克斯公司 Recombinant fibrinogen

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995024929A2 (en) * 1994-03-15 1995-09-21 Brown University Research Foundation Polymeric gene delivery system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626863A (en) * 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
CN1091315A (en) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 Fibrin sealant compositions and methods for utilizing same
US5833651A (en) * 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995024929A2 (en) * 1994-03-15 1995-09-21 Brown University Research Foundation Polymeric gene delivery system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0077227A1 *

Also Published As

Publication number Publication date Type
JP2003502047A (en) 2003-01-21 application
WO2000077227A1 (en) 2000-12-21 application
EP1208212A1 (en) 2002-05-29 application
CA2375346A1 (en) 2000-12-21 application

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Legal Events

Date Code Title Description
17P Request for examination filed

Effective date: 20020109

AK Designated contracting states:

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Despatch of supplementary search report

Effective date: 20070314

RIC1 Classification (correction)

Ipc: A61K 48/00 20060101AFI20070308BHEP

17Q First examination report

Effective date: 20070716

RAP1 Transfer of rights of an ep published application

Owner name: VIVOLUTION A/S

18D Deemed to be withdrawn

Effective date: 20080327