EP1197430A1 - Sealing ampoules by means of a laser beam - Google Patents

Abstract

The arrangement has a filling station (24a), a sealing station (26a) and a delivery device (12a) for delivering empty ampules (18a) to the filling station and then to the sealing station. The sealing station has at least one laser (28a) for melting the ampoule fill opening closed using a laser beam.

Description

The invention relates to an ampoule filling and closing device, comprising: a filling station for filling ampoules, a closing station for closing ampoules by melting an ampoule filler opening, a conveyor with an ampoule conveyor line for Feeding empty ampoules to the filling station and filled ampoules from the filling station to the closing station and for discharging filled Ampoules from the capping station. The invention further relates to a Method of closing an ampoule by melting one Ampoule opening.

Ampoules are conventional, especially glass ampoules (especially medical glass ampoules) intended for larger ones Production volumes designed (e.g. pharmaceutical Products) filled and sealed by devices of the type mentioned, in which the sealing station comprises at least one gas burner in order to melt the respective ampoule using a gas flame. satisfactory So far, sealing results have only been achieved in that the ampoules be melted by the gas flame and that then a Ampoule skewer of the ampoule is pulled off using a skewer puller. According to DE 38 10 940 C2, consideration has already been given to when closing a single ampoule, use an Melt infrared lamp. Because of the energy density of infrared radiation an infrared lamp must be doubted whether in a practical Use of ampoules in this way at all is possible. If reliable closing is possible at all, So are the required radiation times for the respective ampoule so high that the proposal of DE 38 10 940 C2 is no alternative to that represents conventional closure using gas burners. This is all the more true that infrared lamps in a wavelength range emit (about 1-3 µm), in the usual types of glass not or only very absorb weak radiation so that ampoules made of special glass are used should be.

Although laser radiation has been used for shaping and remelting for some time or also used for the heat treatment of workpieces made of glass (cf. for example EP 0 794 031 A2 and EP 0 076 925 A1), only ampoule filling and closing devices still exist on the market of the type mentioned, in which the ampoules under Use of gas burner flames in the manner described be closed. There are sufficient reasons for this, the gas burners to be replaced by other heating agents because of the use of gas burners namely, is disadvantageous in many ways. So there is a high one Installation work for the gas supply to the gas burner. The one from the Heat emitted by gas burners must pass through an extraction device to be dissipated, resulting in a particular in pharmaceutical Area of application frequently provided laminar air flow in the area the conveyor line is disrupted. There is also constant monitoring of the Ignition or burning of the gas flame required. in case of a It takes the system a long time to light the burner Start up so that the burners can burn in the event of an emergency stop and accepts that currently under the influence of the burner standing ampoules are melted down. You can also use the Adjust heat emitted by burners only with difficulty and imprecisely, so that to wish the reproducibility and documentability of the production leaves. Production security is also in need of improvement. Furthermore, the operation of the device is relative due to the gas burner complicated and prone to errors. The gas burners must be in regular Intervals are exchanged, which means a correspondingly high maintenance effort means. Furthermore, hot parts in the area of Gas burner operators are injured. With regard to pharmaceutical Products that have to meet the highest purity requirements there is also the problem that soot particles are created by the gas flame that can hardly be kept completely out of the interior of the ampoule can be. In that the ampoules are traditionally pulled off an ampoule skewer are closed, the soot entry in the Ampoules minimized. In itself, however, means withdrawing ampoule skewers a higher effort on the one hand with regard to corresponding Pullers of the device and on the other hand in terms of material and Manufacturing effort for the ampoules themselves.

Despite these reasons, in and of itself for a replacement of gas burners speaking through other means has so far continued in practice Gas burner set. This may be because, especially in the case of medical ampoules for pharmaceuticals highest demands on the Tightness and sterility exist, with the use of gas burners on the one hand due to the high heat for maintaining or Establishment of sterile conditions in the area of the sealing station is beneficial and, on the other hand, the mechanical one exerted by the gas flame Pressure on the ampoule wall material causes the melted to bleed Wall material, especially glass, and thus a reliable Melting without capillary through openings promotes.

However, it has now been found that laser radiation can also be used Allow ampoules to melt reliably. According to the invention therefore suggested that the capping station have at least one laser is assigned to fuse the ampoule filler opening below Exposure to laser radiation.

That reliable melting using laser radiation is possible, may surprise, because the absence of a gas flame mechanical gas flame pressure is missing. A laser beam also acts on one comparatively localized spot on an ampoule as opposed to the larger exposure to a gas flame. There is no question that by means of a laser beam glass in the sense of the above Writings EP 0 794 031 A2 and EP 0 076 925 A1 can be edited. However, it was not possible to close ampoules expected, because of the comparatively localized Laser beam exposure and the lack of mechanical gas flame exposure had to be feared that reproducible melting is not possible without capillary passages.

By eliminating gas burners, which has become possible according to the invention there are great advantages. For one thing, the above is not necessary Installation and monitoring effort. The laser radiation can targeted the respective ampoule are heated so that no heat from the Plant must be removed. A possibly provided laminar air flow is therefore not disturbed. The ampoule filling and closing device can start up and shut down quickly the laser radiation source (the at least one laser) can be switched on and off as required. For a brief interruption of the Laser beam can also be a laser beam trap or the like in the Laser radiation path are introduced. Regardless of whether the laser switched on and off or a laser beam trap in the beam path is introduced, the action of laser radiation on the respective processed ampoule or the respective processed ampoules without essential Delayed time should be interrupted, for example in the case an emergency stop or when shutting down the system. In order to can reliably prevent ampoules in such a situation be melted down so that the device is not essential Committee produces. It is particularly important that the laser exposure is controllable precisely and reproducibly, so that a high Production security is achieved. The production parameters can recorded, i.e. documented, with regard to the Quality assurance is an important advantage. The controllability of the Lasers can affect the laser exposure, in particular the laser power current cycle time of the device or the current duration of exposure be adapted to the laser radiation, for example when starting up or shutdown of the system or also in the event of an emergency stop is, despite the associated change in the operating state of the Set up ampoules that have already been filled properly or start filling and melting ampoules. As a result, high productivity without significant rejects Ampoules reached.

The good controllability of the laser exposure both with regard to the Ampoule issued thermal energy as well as regarding the possibility of that Target laser action in a specific area of the ampoule localize also offers the advantage of undesired heating the substances introduced into the ampoule, for example sensitive ones Pharmaceuticals, can be prevented. This also contributes to a very high one Production security at. Furthermore, the ampoule filling and closing device based on their filling and sealing capacity (ampoules per Unit of time) can be made much more compact than in the case of Capping stations with gas burners is possible. Provided the filling and Closing under clean room conditions is less Clean room space required. Another advantage is that an injury from People are excluded from heated parts. It just has to usual, known in connection with the use of lasers Measures to protect against laser radiation are taken, for example Piping the laser radiation, providing beam traps and The like, depending on the design of the ampoule filling and closing device and the arrangement of the laser relative to the sealing station. The one for this the effort required is comparatively low.

If the problem of a gas burner is not a problem Soot entry in the ampoules no longer exists, so the Capping station a device for withdrawing ampoule skewers to the ampoules by melting and subsequent Pull off the respective ampoule skewer to close. Because of this Pulling off the respective ampoule skewer will namely converge promoted the melted ampoule wall material, in particular glass, so that with excellent reliability an excellent tightness Ampoules can be achieved. This also allows a good shape of the ampoule head, i.e. a good ampoule geometry with sufficient Wall thickness and sufficient mechanical strength.

However, it has also been shown that with careful coordination the Parameters of the laser exposure include closing the ampoules without Pulling off a respective ampoule skewer is possible without compromising the quality of the ampoule closure, especially the ampoule head or the ampoule tip. To do this suggested that the ampoule be melted onto the ampoule opening adjoining ampoule section until the Ampoules aperture Together Running / coincident ampoule wall material of the melted ampoule section is closed.

A processing gas can be used to support the closing process Aim at a softened section of the ampoule to point at it mechanical action. For this purpose, the sealing station can Have processing gas supply device to the processing gas to soften sections of the ampoule. The use of processing gas is particularly without in the case of closing ampoules Removal of ampoule skewers is advisable to the convergence / collapse to promote the ampoule wall material. But you can Also keep in mind, in the case of pulling out ampoule skewers additionally mechanically acting on the softened sections of the ampoule Use processing gas.

The proper closing of the ampoules with high tightness and good geometry of the ampoule head is promoted if the Ampoule is preheated before the actual closure. The preheating allows that in the ampoule above the level contained gas (air or protective gas) to a sufficiently high temperature is brought and corresponding to that with the temperature increase accompanying expansion can escape from the ampoule before it is closed. Preheating is also helpful, sufficient Introduce thermal energy into the ampoule material and a certain Distribution of the thermal energy in the ampoule spit or in the Ampoule opening to allow adjacent ampoule sections before the ampoule is sealed so that there is no substantial build-up from tension in the head area of the sealed ampoule, which after the ampoule has cooled, the mechanical stability of the ampoule could affect. This is a high mechanical Resilience of the fused ampoule heads reached. Regarding the The device according to the invention is therefore proposed that the Sealing station designed for this or a separate preheating device is intended for the respective ampoule to be sealed preheat first during a preheating phase before the Ampoule during a closing phase due to the action of laser radiation and if necessary closed by pulling off an ampoule skewer becomes.

The preheating can be compared to a closing phase separate preheating phase. You can preheat it and also carry out the closure in one go without mandatory a pre-heating phase and a closing phase are distinguishable. It is essential that on the one hand that in the ampoule contained gas before closing the ampoule fill opening by molten Wall material is sufficiently heated and according to it temperature-related expansion can escape from the ampoule and that on the other hand, the ampoule or the ampoule spit such thermal energy records that a spatial temperature distribution is achieved, which after the closing and subsequent cooling of the ampoule none leaves significant tension in the head area of the ampoule. It is basically also possible, the ampoule continuously with laser radiation certain, possibly comparatively lower (possibly constant permanent) power, so that the ampoule is heated and expansion of the gas in the ampoule is gradually warmed until finally the ampoule wall material melts and the ampoule opening is then closed. For short exposure times for laser radiation, short cycle times if necessary, but it is advantageous to actually compare one to provide a preheating phase in a closing phase in which the energy required for preheating in a short time interval Ampoule is supplied. This then follows, possibly in a time Distance, the closing phase, in which the ampoule has more energy is fed until the ampoule material melts and the ampoule opening either by pulling an ampoule skewer or by converging / collapsing Ampoule wall material is closed, if necessary with the support of the closing process using a processing gas.

Compared to the known preheating by gas burners in the case a conventional device as described above, in which the Ampoules are melted down by gas flames, this is here proposed preheating a significant difference. The conventional Preheating was used to provide sufficient thermal energy at all bring the ampoule wall material, because the gas burner in the Material heat output is comparatively low. by virtue of the correspondingly long exposure times of the gas flame could in the Air contained in the ampoule absorbs sufficient heat and expands, before the ampoule was closed.

In the case of the use of laser radiation, it can basically be extreme achieve high radiation powers, so that the introduction is sufficient Thermal energy is no longer a problem, and preheating to that extent is unnecessary. However, preheating has a value than that the occurrence of tension and the formation of capillaries in the Locking area can be counteracted by escaping air and the resulting head or cap geometry (in particular Wall thickness in the closure area) can be positively influenced.

The ampoule can also be preheated using laser radiation. For this purpose, the preheating device or the sealing station at least one laser can be assigned. It can be your own act only for the preheating laser or a laser, which is used both for sealing and for preheating. You will choose the solution here in terms of the processing times to be achieved is the cheapest. The preheating can be done with another or the same laser power as the actual sealing.

The preheating can also be done using at least one non-coherent electromagnetic radiation source (depending on the Absorbance of the wall material of the ampoules used possibly an infrared radiator) and / or a heating element arrangement, in particular heating coil arrangement, for which the preheating device or the closing station can be designed accordingly. Preheating using laser radiation is preferred.

For short processing times, especially short cycle times in the case of a clocked device can preheat during a transport phase of the respective ampoule, especially during the Transport of the ampoule from the filling station to the closing station. As a general rule can at least partially preheat or / and close ampoule moved along a conveyor line (the ampoule conveyor line) respectively. For this purpose, it is proposed that the at least one laser assigned beam guide means are suitable, the laser radiation corresponding to a movement of the ampoule through the conveyor to track. The tracking of the laser radiation is opposite to one possible movement, possibly swiveling, of the laser itself preferred because the mechanical effort is lower in the first case. Corresponding beam guiding means are available in large numbers to the person skilled in the art available, for example on swivel mirrors, scanners, Polygon mirror wheels and the like thought.

The ampoule can at least be closed when closing and / or preheating two directions are irradiated with laser radiation. You can do this at least two lasers can be arranged in such a way and / or can Corresponding beam guiding means are assigned to at least one laser his. As a result, the ampoule or the Ampoule skewer can be reached in the circumferential direction without a Rotation of the ampoules around an ampoule axis is required. Through the uniform heating is the occurrence of tensions in the cooling or cooled wall material counteracted.

But you can also the respective ampoule when closing or / and Let preheating rotate around an ampoule axis, regardless of whether the laser radiation from one direction or from multiple directions the ampoule is blasted. You only see radiation from the ampoule in one direction, the ampoule is rotated anyway uniform heating is achieved so that the ampoule is reliable can be closed without significant tension in the Ampoule head occur. With regard to the device according to the invention it is therefore proposed to use a corresponding ampoule rotation device provided.

Depending on the substance to be filled or filled into the ampoule it, for example, in terms of sufficient durability or for Avoiding oxidation should be appropriate, the ampoule with protective gas, for example nitrogen. The ampoule can therefore before Seal, especially before or / and during filling, during the Preheating or / and during the sealing process. For this can the device according to the invention with a gassing device are provided for gassing the ampoules during filling or / and during the transport of the ampoules from the filling station to the closing station or / and during the preheating or / and during the Closing. In the case of mechanical impact from machining gas the processing gas is usually the same gas as for the Use fumigation.

The gassing device can have a gassing needle for this is trained to fumigate a respective ampoule through the closing ampoule filling opening in the ampoule until it is reached immerse yourself in an immersion position. The fumigation needle can Have gas outlet opening that is lower than that in the immersion position Irradiation point of the ampoule at which it is irradiated with laser radiation will lies. Preference is given to preheating and / or during an initial phase of gas sealing by being in the immersion position arranged fumigation needle insertable into the ampoule. So it will suggested during preheating or / and during a Initial phase of sealing gas through the outlet opening Introduce fumigation needle into the ampoule, keeping the outlet opening deeper than the irradiation point of the ampoule. Through the targeted and accurate controllable exposure to laser radiation can be reliably prevented, that the fumigation needle is damaged or the vial is closed is hindered by the fumigation needle. Before closing the Ampoule through converging wall material or by pulling the The fumigation needle can withdraw the spit from the ampoule in good time become. If necessary, you can also use laser radiation briefly interrupt for gassing with the needle. A Excessive heating of the fumigation needle and loss of thermal energy for the melting process can be prevented by the Fumigation needle is mirrored so that it acts as a mirror for laser radiation or / and as a mirror for radiation emitted by the ampoule wall material Heat radiation serves.

To be processed with the device according to the invention, that is to say Filling and closing ampoules can be set up in one device Condition with fully formed ampoule fill opening. The ampoules are therefore included by the ampoule manufacturer right from the start Ampoule filler opening made. But ampoules can also be used are used, which are delivered in the closed state, the are sealed by the ampoule manufacturer during manufacture and accordingly (still) have no ampoule filler opening. While the transport of the ampoules to the pharmaceutical manufacturer is one Contamination of the interior of the ampoule is reliably excluded. With that Such ampoules are processed in the device according to the invention can, the device can have an opening station that the Ampoule filling and closing device in the closed state supplied ampoules opens before being fed to the filling station. Because the opening takes place just before the feed to the filling station, is opposite of open ampoules of the apparatus and handling Effort reduced since washing and / or sterilization can be omitted.

The invention also relates to a method for opening a closed one Ampoule by melting an ampoule opening, possibly as part of one Ampoule treatment method comprising a method of closing an ampoule by melting an ampoule opening like described above. According to the invention it is proposed that Melt the ampoule opening under the influence of laser radiation, if necessary with additional use of a mechanical tool for opening expansion or / and to remove molten ampoule wall material. With regard to the opening station, it is accordingly proposed that this is assigned at least one laser for opening the ampoules below Exposure to laser radiation.

It is particularly useful to open the ampoules in at least three stages perform. A preheating stage serves to keep a negative pressure in dismantle the closed ampoule, so when opening the ampoule no ambient air or gas is drawn in. This can connect an overpressure relief stage to the overpressure in the Dismantle the ampoule. A (comparatively small) compensation opening can be used for this generated in the ampoule by laser radiation. For example you can use a high-energy laser pulse that opens the compensation opening in the ampoule wall by evaporation of ampoule wall material manufactures. Then the actual ones can be opened in one step Ampoule fill opening are generated by laser radiation, if necessary with additional use of a mechanical tool for opening expansion or / and to remove molten ampoule wall material.

Filling the ampoules, closing and / or opening the Ampoules can be shielded from environmental influences Conditions such as clean room conditions and / or air laminar flow conditions take place, for example, when higher requirements apply the purity and sterility are to be met. For this purpose, the facility can Have shielding chamber in which the filling station, the closing station and possibly the opening station are arranged. Basically can the at least one laser is arranged within the shielding chamber his. However, it is preferred that the at least one laser is outside the Shielding chamber is arranged and the laser radiation through a for the laser radiation transmissive window arrangement into the shielding chamber is fed. This ensures that the laser is good can be arranged accessible without maintenance or Adjustment of the laser to dirt or germs in the area of the filling station, the closing station and possibly the opening station. It also prevents outgassing of sealing components and the like of the laser in the area of the mentioned stations. The shielding chamber is preferably a clean room chamber or / and air laminar flow chamber.

The ampoule filling and closing device according to the invention can at least with their filling station, their closing station and possibly theirs Opening station in a room of higher air quality, in particular Clean room, be arranged, whereas the laser is preferably in one Adjacent room, for example washroom, arranged lower air quality is. The laser can, for example, in the latter case Maintenance personnel of the laser manufacturer can be serviced without it must be feared that dirt or germs in the room higher Air quality are carried in.

A laser beam shaping arrangement can be used for the at least one laser a laser beam shaping arrangement can be assigned or in the laser be integrated to a predetermined intensity distribution on the respective ampoule acting laser radiation during preheating or / and during closing or / and during opening provided. The intensity distribution can be related to the geometry (in particular ampoule size, wall thickness) and the ampoule wall material be coordinated to optimize the closing of the ampoule. the goal is it, a sufficient wall thickness of the ampoule head without essential To reach tensions in the material after cooling. The laser beam shape Here is an important parameter that is empirical for each sealing ampoule type can be matched. For example it is conceivable that an elliptical intensity distribution with orientation of the Longitudinal axis of the ellipse parallel to the longitudinal axis of the ampoule, at least for certain Ampoule formats is beneficial to the head shape and material thickness in the Optimize head. It is also conceivable to have two in the longitudinal direction of the ampoule to provide spaced laser focal spots, on the one hand, the Focus on warming and on the other hand a melting zone sufficient size. There are many here Possibilities and general statements are due to the different existing ampoule formats difficult.

It is also proposed that the at least one laser Laser beam guide arrangement is assigned to the laser radiation corresponding to a conveying movement of the respective ampoule along the Track conveyor line, and / or the laser radiation when pulling the track each ampoule skewer in the skewer pulling direction or so to redirect the detachment of the spit from the rest of the ampoule, in particular an interruption of any that may arise when pulling off Material thread, is promoted, and / or the laser radiation after sealing of the respective ampoule, in particular after removing the Ampoule skewer, or / and after opening the ampoule to one forward the following ampoule. The laser beam guidance arrangement can have laser beam shaping properties at the same time, so that generally from a laser beam shaping and guiding arrangement can be spoken.

As a preferred further development it is proposed that when closing or / and a reflection arrangement when preheating the respective ampoule assigned, the radiation emanating from the ampoule, in particular Heat radiation and / or laser radiation reflected from the ampoule, reflected back to the ampoule and / or the laser radiation in Directed towards the ampoule and / or on an ampoule section concentrated. By reflecting back heat radiation or from the Ampoule of reflected laser radiation ensures that the energy of the Laser radiation is used well and accordingly short exposure times for the laser radiation are possible. In the event of a skewer trigger can the reflection arrangement in a skewer trigger member, in particular Skewer pliers, integrated. Additional mechanical effort for a holder and, if necessary, a forward or an entraining movement of the reflection arrangement to or with the ampoule is therefore unnecessary.

It is very advantageous if the ampoule to be closed is a Detection device is assigned to detect one of the ampoule outgoing process radiation, in particular heat radiation and / or on Relaxation of excitation radiation returning to during or / and after preheating or / and during sealing or / and when opened, a treatment state of the respective ampoule determine. The treatment status can be the degree of warming, for example (Temperature) of the ampoule which is decisive for the closing Area. This treatment status can be evaluated to at least one intrinsic parameter of the ampoule and / or the ampoule material (For example material thickness or / and geometry or / and fluid state or / and coloring of the ampoule wall material). Out the evaluation of the process radiation is a conclusion on each treated ampoule possible. This is beneficial when different Ampoule types or ampoules with different filling or filling quantity should be closed. A sorting of the ampoules, if necessary spit sorting, before filling and closing is therefore unnecessary. It can also Device according to the invention for this development for ampoules can be used with regard to their geometry, wall thickness, etc. spread comparatively heavily, because the production is less tight Tolerances were observed. In such a case or in the case of Processing of ampoules of mixed sorting can be, for example, the Treatment status, in particular the temperature, of the ampoule after the Preheating can be determined. Depending on the detected Treatment status can then be set, for example, the laser power be used when the ampoule is subsequently closed becomes. Is the temperature not so high, perhaps because of the material thickness and accordingly the thermal capacity of the ampoule is relatively large, so a higher laser power can be set for closing. is on the other hand, after preheating, a relatively high temperature achieved because about the material thickness and accordingly the heat capacity is lower, a lower laser power is sufficient for the closure and too high a laser power may seem even with regard to an optimal one The top of the ampoule can be harmful, as this will cause wall material (in particular Glass) could be evaporated. Generally speaking, at least an operating parameter of the device, in particular of the at least one Lasers or at least one process parameter depending on the Treatment status can be adjustable.

mittlere Leistung der Laserstrahlung beim Vorerwärmen oder/und beim Verschließen oder/und beim Öffnen,

im Falle eines Pulslasers: Pulsfrequenz oder/und Pulsenergie der Laserstrahlung beim Vorerwärmen oder/und beim Verschließen oder/und beim Öffnen,

Bereich der Ampulle, auf den während des Verschließens mit Laserstrahlung eingewirkt wird,

im Falle des Spießabziehens: Spießabziehgeschwindigkeit oder/und Abstimmung des Abziehzeitpunkts in Bezug auf den Beginn der Lasereinwirkung für das Verschließen,

im Falle der Vorerwärmung: Vorerwärmungsdauer oder/und zeitliche Abstimmung des Beginns des Verschließens oder/und Bereich der Ampulle, auf den während der Vorerwärmung eingewirkt wird,

im Falle der Ampullenrotation: Rotationsgeschwindigkeit der jeweiligen Ampulle beim Vorerwärmen oder/und beim Verschließen,

Intensitätsverteilung der Laserstrahlung auf der jeweiligen Ampulle,

Zufuhr von Bearbeitungsgas oder/und Begasungsgas.

Various operating or process parameters come into consideration, which can be adjusted for an optimization of the closure, the setting being adjusted depending on the treatment status of the respective ampoule and / or possibly depending on a temporal treatment program for the respective ampoule. Without wanting to give a final list, the following operating parameters or process parameters are considered, for example:

average power of the laser radiation when preheating and / or when closing or / and when opening,

in the case of a pulse laser: pulse frequency and / or pulse energy of the laser radiation when preheating and / or when closing or / and when opening,

Area of the ampoule, which is acted upon by laser radiation during sealing,

in the case of skewer peeling: skewer peeling speed and / or adjustment of the peeling time in relation to the start of the laser action for the closing,

in the case of preheating: preheating duration and / or timing of the beginning of the closing or / and area of the ampoule which is affected during the preheating,

in the case of ampoule rotation: rotational speed of the respective ampoule during preheating and / or when closing,

Intensity distribution of the laser radiation on the respective ampoule,

Supply of processing gas and / or fumigation gas.

With regard to a recording that may be required for quality assurance operating parameters of the facility during filling and closing of ampoules and treatment conditions of the ampoules in the In the course of their processing, it is advantageous if the invention Device has a recording device for this purpose. This allows process parameters and / or treatment states to be identified simple record and stand as evidence of proper Operation of the plant and as a basis for optimization of the process parameters available.

In the ampoule filling and closing device according to the invention can it is an institution which is responsible for the promotion of the Ampoules along the ampoule conveyor run continuously with itself with the ampoules moving along a respective conveyor section Treatment organs and / or tracking the laser radiation according to the ampoule movement. Alternatively, it can also be a facility acting longitudinally in relation to the promotion of ampoules the ampoule conveyor line works in cycles with stationary treatment organs or / and at least intermittent fixed laser radiation guidance, if necessary with switching between several laser radiation guidance paths.

There are various variants with regard to the course of the ampoule conveyor line conceivable. For example, the ampoule conveying path can at least be linear in sections. A particularly advantageous training sees proposes that at least one linear conveyor section parallel to one Laser radiation path runs in such a way that of at least one at least one at least one ampoule moving along the conveying path from one side with propagating along the laser radiation path Laser radiation is irradiated. You can then use stationary laser radiation paths work, so does not need laser beam tracking or Switching between different laser radiation guidance paths, if the ampoules are conveyed in such a way that they correspond to one certain treatment program providing exposure to laser radiation moved into the laser radiation and out of the laser radiation again be moved out. The simplest variant is that an ampoule on the The beginning of the linear conveyor section enters the laser radiation and at the end of the linear conveyor section, the ampoule such interaction with the laser radiation and possibly additional ones Machining effects (such as treatment gas and / or skewer extraction) learned that it is closed at this end. Based on the Basic principle that a linear conveyor section is based on the specified way parallel to a laser radiation path extends, many advantageous variants are possible. This basic principle is for both clocked and continuously working systems suitable.

In this context it should be mentioned that not only one Conveying movement of the ampoules can be used with this To bring laser radiation into interaction, i.e. in an area of influence to move in the laser radiation, and interact with to end the laser radiation, i.e. the ampoules from the area affected the laser radiation. Another way is by tilting or swiveling the respective ampoule, which may a conveying movement is superimposed on the ampoule or one of the laser radiation section of the ampoule to be exposed or suspended in the To move the laser radiation in or out of it move out, so that switching the laser radiation on or off Switching between different laser radiation guidance paths is unnecessary. It is particularly thought to do this principle use a sealed vial from the laser radiation swivel out or topple when there is no more laser radiation to be suspended anymore. This principle alone or one Combination of this principle with the aforementioned principle of moving in or out of the ampoule due to a conveying movement opens up many possibilities, systems according to the invention advantageous interpreted.

As an alternative or possibly in combination with a section by section linear training of the ampoule conveyor line is proposed that the ampoule conveying path is curved at least in some areas, is in particular at least in sections arc-shaped. from mechanical effort, it is particularly simple if the conveyor comprises a rotary device with a rotary machine which defines the arcuate section of the ampoule conveyor. In such a rotary device can be a laser beam guidance arrangement or / and a laser beam reflection arrangement can be integrated, whereby realize a great compactness without great mechanical effort leaves.

It has been used several times by beam guidance and / or beam shaping agents spoken. These means can be at least one of the following Assemblies include: diffractive optics, such as holographic Element; refractive optics, for example a lens arrangement; a swivel mirror arrangement, possibly with a flat field lens, for example a scanner; a reflection surface wheel, for example a polygon wheel; a reflective surface pivoting member; an optical fiber; a deflecting mirror; a beam splitter arrangement. Generally speaking be that the entire arsenal of applied optics and Optical components used in laser technology are used can.

For a high filling and closing performance of the invention It is proposed that the filling station, the closing station and if necessary the opening station are suitable for simultaneously closing several ampoules treat or edit. The stations mentioned can be used for this each have several organs serving the same purpose, for example a plurality of filling elements in the case of the filling station, one A plurality of closure members, in particular skewer trigger members, in Case of the sealing station etc. Also the others already mentioned Components, such as gassing needles, treatment gas supply device etc., can be provided in multiple versions accordingly. There are several options with regard to laser radiation. So can to provide a correspondingly strong laser, its laser radiation through a beam splitter arrangement into the required number of partial laser beams is divided. But you can also use a variety of lasers provide. One will resort to the solution here that Manufacturing costs and maintenance costs appear cheapest. On the only laser would have the advantage that only one laser serviced and adjusted must become. But a laser with high power is comparatively expensive. It may be due to the relatively high investment costs for a very powerful laser better, a plurality of lasers to provide correspondingly low power. This would also have the advantage that in the event of a failure - which is normally not to be expected - a Lasers still an emergency operation of the ampoule filling and closing device it is possible.

According to a preferred development, the ampule filling and closure device a marking and / or labeling device for marking and / or labeling ampoules using Laser radiation on. A separate marking / labeling laser can be used for this be used or - this training is preferred - it can be a Part of the laser radiation of the laser arrangement provided anyway be branched off by appropriate beam guidance and Beam forming means to form an inscription / marking beam which for example by means of a scanner for marking and / or labeling the ampoule is inserted. A separate marking or label the ampoules, for example with labels, may then not be necessary. Even if additional adhesive labels or the like with more detailed Information is provided, but can by marking or Lettering immediately in the course of filling and closing or immediately after the closure a confusion of Ampoules can be prevented. Also by registered mail Markings or labeling texts in the ampoule wall material the laser radiation clearly identifies the individual ampoule without leave this marking behind without leaving any traces is removable. A re-labeling is at least provable in this way and the manufacturer can draw conclusions about the distribution channel of ampoules, should ampoules in a manner not intended by the manufacturer be redistributed.

The at least one laser is a laser which is matched to the ampoules used in terms of its emission wavelengths and laser power. In the case of glass ampoules (medical glass ampoules are primarily considered), the use of an infrared laser, for example a CO ₂ laser or neodymium YAG laser, is advantageous. Excellent sealing results have been achieved in particular with the infrared laser radiation from at least one CO ₂ laser. Since the emission wavelength of CO ₂ lasers is 10.6 µm, ampoules made of all common types of glass are suitable for being sealed with CO ₂ laser radiation.

It should also be mentioned that the preferred CO ₂ laser can be a so-called "field-off laser", which has advantageous operating properties and can be easily integrated into a machine. It should also be mentioned that a monomode operation of the laser used is not necessary, so that space grids and the like can be dispensed with in the laser, so that comparatively inexpensive procurement of the laser is possible.

The invention further relates to a device for processing a Workpiece by means of electromagnetic radiation, possibly in a facility as described above, with means for generating electromagnetic Radiation, especially laser radiation. Accordingly, it can the workpiece is an ampoule to be sealed. The The invention further relates to a method for machining a workpiece by means of electromagnetic radiation, in particular a method for Closing an ampoule, possibly as a further development of the preceding one described ampoule closure method. The invention further relates to a mirror for reflecting electromagnetic radiation, in particular of laser light, in particular for use in an inventive Device or in a method according to the invention, the has a base body.

Through the publication "Precision Machining with Solid State Lasers", Page 185 ff., VDI-Verlag, 1995, is an institution of the type concerned known in which a laser means for generating electromagnetic Radiation forms and that for processing the surface of a workpiece serves. In the known device, laser light from an Nd-YAG laser via adjustable mirrors, which form beam guiding means, onto a workpiece directed, the surface of which by the action of laser light Surface hardening is subjected. The adjustable mirrors allow it here, the beam spot of the laser two-dimensionally along the To move the surface of the workpiece to be machined.

It is disadvantageous, however, that if, for example, one of the first machined surface opposite surface of the workpiece machined machining is interrupted and the workpiece is rotated must become. This can either be done by hand, which is time consuming and is personnel and thus expensive, or it is expensive Positioning devices required, by means of which a feed movement and / or a rotary movement of the workpiece can be carried out.

Through the mentioned publication is also a procedure of the concerned Kind known.

The invention has for its object a device and a To specify the procedure of the type in which the Processing of workpieces, especially ampoules, from several sides is simplified.

To solve this problem, the invention proposes that To equip the device with beam guidance means that are electromagnetic Radiation from at least two directions on the material to be processed Align the workpiece, especially the ampoule to be sealed. Accordingly is proposed in relation to the procedure that electromagnetic radiation, especially laser radiation, at the same time at least two directions on the workpiece to be machined, in particular the ampoule.

The basic idea of the teaching according to the invention is that Workpiece simultaneously by means of the electromagnetic radiation to work in several directions. For example, if a workpiece from two sides facing away from each other can be processed according to the invention processing is done simultaneously from these two sides, so that turning the workpiece after machining one side like this is required in the prior art, is omitted. That way complex positioning devices for rotating the workpiece are not required so that the device according to the invention is simplified and therefore is more cost-effective.

Due to the simultaneous machining of the workpiece by several Pages work the device according to the invention and the inventive Time-saving process, so that when machining workpieces high effectiveness can be achieved. This saves in particular Costs when large quantities of workpieces have to be processed.

The device according to the invention is simple and robust in construction, so that time-consuming adjustments of the device during operation are not necessary. To this In this way, further time and cost savings are achieved.

According to the invention, workpieces can be viewed from several directions simultaneously are processed right through to simultaneous machining of the workpiece from all sides.

The machining of the workpiece can be done, for example, by soldering, Melting, separating, joining, coating, removing, hardening or in one any other direct or indirect processing. It is for example when machining a workpiece using heat possible the electromagnetic radiation on an intermediate element in which the workpiece to be machined is added is, the electromagnetic impinging on the intermediate element Radiation leads to heating of the intermediate element, the Heat radiation through heat conduction on the workpiece to be machined is transmitted. Overall, the device according to the invention and The inventive method can thus be used in a variety of ways.

The device according to the invention and the method according to the invention enable homogeneous machining of workpieces.

A further development of the device according to the invention provides that the Beam guiding means have at least one reflection surface, which the incident electromagnetic radiation on the workpiece to be machined reflected.

A further development of the aforementioned embodiment provides that the Reflection surface is formed by at least one mirror. This Embodiment is simple and inexpensive to manufacture.

According to the invention, the geometry of the reflection surface corresponds to that respective requirements, for example with regard to a desired one Intensity distribution of the reflected electromagnetic radiation the workpiece, selectable within wide limits. An expedient embodiment however, provides that the reflective surface of the mirror narrowed in a funnel shape towards the workpiece to be machined.

A particularly advantageous development of the aforementioned embodiment provides that the reflective surface of the mirror essentially is rotationally symmetrical.

The geometry of the rotationally symmetrical reflection surface of the mirror is here within wide limits and according to the respective requirements selectable. It is also possible to design the mirror so that, for example heat radiation emitted from the workpiece from the mirror is reflected back onto the workpiece. This leads to a targeted Utilization of the resulting process heat and thus a more effective one Utilization of the energy used for processing. In corresponding Way it is possible to be reflected from the workpiece electromagnetic radiation back onto the workpiece using the mirror to reflect.

An extremely advantageous development of the embodiment with the rotationally symmetrical reflection surface provides that the reflection surface of the mirror conical to the workpiece to be machined narrows. Due to the conical shape of the reflective surface, for example when machining a rotationally symmetrical workpiece, not only in the circumferential direction, but also in the axial direction of the Workpiece a homogeneous intensity distribution of the reflected radiation achievable on the workpiece. In this way it is even Processing, for example a uniform removal of material on the Surface of the workpiece, in the entire effective range of the reflected allows electromagnetic radiation.

In the embodiments with the mirror is expedient in that Mirror or in a part connected to the mirror an entry opening for inserting the workpiece into the effective range of the electromagnetic Radiation formed. This embodiment is simple and inexpensive producible, for example, in that in the base body of the Mirror a hole is made.

It is expedient in the aforementioned embodiment that Insertion opening to the rotational symmetry axis of the reflection surface in the essentially coaxial. In this way, the workpiece is along the Rotational symmetry axis of the reflective surface in the effective range of the electromagnetic radiation introduced.

According to the invention, any electromagnetic radiation can be used to machine the workpiece, for example infrared radiation or electron radiation. A particularly advantageous embodiment provides, however, that the means for generating electromagnetic radiation have at least one laser. A large selection of lasers are available as robust and inexpensive components, and the power can be selected within wide limits according to the requirements of the respective machining process. Any lasers suitable for material processing can be used, for example CO ₂ lasers or Nd-YAG lasers.

A further development of the embodiment with the laser provides that the Beam guiding means are formed by optical fibers which carry the laser light of the laser or the laser from at least two directions towards it Straighten the machining workpiece. In this embodiment, one is Machining of the workpiece even in hard-to-reach places allows. By appropriate choice and arrangement of the optical fibers are also complicated geometries when machining the workpiece realizable.

Basically, it is sufficient if the electromagnetic radiation from a corresponding radiation source, for example with laser light from a laser, directly onto the workpiece using the beam guiding means is judged. According to one embodiment of the invention However, device are beam shaping agents that are in the path of propagation Radiation between the means for generating electromagnetic Radiation and the workpiece to be machined are provided. In this embodiment, the electromagnetic radiation a desired intensity distribution of the electromagnetic radiation can be achieved on the workpiece.

A further development of the aforementioned embodiment provides that the Beam shaping means at least one diffractive optic, for example a Hologram, and / or at least one refractive optic, for example a Axikon. Such optics are available as standard components in diverse selection available.

The electromagnetic radiation can be emitted by the beam shaping means shape in almost any way. A further development of the embodiments with the beam shaping means and the rotationally symmetrical However, the reflecting surface provides that the beam shaping means Shape incident electromagnetic radiation so that on the Reflecting surface of the mirror a beam spot is formed, its projection in a perpendicular to the rotational symmetry axis of the reflection surface Plane is essentially concentric to the axis of rotational symmetry. In this way, a rotationally symmetrical reflection is electromagnetic Radiation on the workpiece achieved what when machining rotationally symmetrical workpieces is particularly advantageous.

In the aforementioned embodiment, the projection of the beam spot can in an axis of rotation of the reflection surface vertical plane essentially circular or essentially be ring-shaped, in particular ring-shaped with a small radial extent, how this is provided by expedient further developments of this embodiment.

Basically, you can work on the surface of the Any intensity distributions of the workpiece according to the invention achieve electromagnetic radiation. A further development of the embodiment with the beam shaping means, however, that this the Shape incident radiation in such a way that in the effective range of the electromagnetic Radiation on the workpiece to be machined substantially homogeneous intensity distribution of the electromagnetic Radiation is achieved. In this way, even processing of the Workpiece ensured.

Basically, it is sufficient if the workpiece before the start of the Machining process is brought into a fixed processing position and remains in this position during processing, so that a positioning device is basically not necessary. A further education of the However, the device according to the invention provides a positioning device Positioning of the workpiece and the beam guiding means relatively to each other. In this way, for example, a movement of the Workpiece relative to the beam guiding means and thus relative to Effective range of electromagnetic radiation can be achieved if this is required. For example, if you want an elongated cylindrical workpiece can be processed, so the axial position by means of the positioning device of the workpiece can be changed relative to the beam guiding means successively the reflected electromagnetic radiation to different to align axial areas of the workpiece. With appropriate Formation of the positioning device is any desired Movement of the workpiece relative to the beam guiding means can be achieved, for example a displacement of the workpiece in X- and / or Y- and / or the Z direction and / or a tilting movement and / or a rotary movement.

In particular in the case of devices according to the invention in which at the same time machining, for example of a rotationally symmetrical workpiece, over its entire circumference, the positioning device by a feed device to the preferably linear Feed of the workpiece relative to the beam guiding means and / or for the preferably linear feed of the beam guiding means relative to the Workpiece be formed, as this is an expedient training of Provides embodiment with the positioning device.

According to another advantageous development of the invention The mirror has its device in the direction of incidence of the electromagnetic Radiation front side one for electromagnetic radiation permeable cover, the cover and the reflective surface of the mirror form walls of a processing chamber in which the machining workpiece is included in its machining position.

The processing chamber can, for example, with respect to the environment be sealable. In this embodiment, material is leaking from the processing chamber into the environment or for example Avoid entry of gas from the environment into the processing chamber. For example, the processing chamber can be evacuated, if that Workpiece to be processed in a vacuum.

Another development of the embodiment with the processing chamber provides that this is an inlet opening for protection and / or Process gas has. In this way the workpiece is under protection and / or process gas atmosphere editable. A particular advantage of Embodiments with the processing chamber is that in the Machining of the workpiece desired machining conditions, for example a vacuum or a protective gas atmosphere or predetermined Temperature conditions, only in the proportionate generated and maintained small volume of the processing chamber Need to become. Because the electromagnetic radiation from outside through the Cover is introduced into the processing chamber, a corresponding radiation source, for example a laser, outside the Processing chamber can be arranged so that large-volume processing chambers in which the radiation source is recorded, are avoided.

In the method according to the invention, the electromagnetic radiation laser light.

In the method according to the invention, it is basically sufficient when the electromagnetic radiation comes from two directions simultaneously the workpiece is straightened, so that machining of the workpiece done from two sides. A particularly advantageous training However, the electromagnetic radiation provides that along at the same time a substantially closed area directed towards the workpiece becomes. In this embodiment, for example, machining of a rotationally symmetrical workpiece at the same time entire scope.

Here, the electromagnetic radiation can be linear Area to be aimed at the workpiece, so that then a linear The workpiece is machined.

However, the electromagnetic radiation can also be in a sheet-like form Area to be aimed at the workpiece, so that then a flat Processing is done.

The shape, size and geometry of the workpiece to be machined are in wide limits selectable. However, it is particularly advantageous if according to the invention an essentially rotationally symmetrical workpiece is processed.

The workpiece can be permanently arranged during processing. A Further development of the method according to the invention, however, provides that the Workpiece during processing relative to the beam guiding means is moved, in particular is moved essentially continuously. On in this way, for example, in the case of a cylindrical workpiece electromagnetic radiation in succession on different axial Align areas of the workpiece.

According to another development of the method according to the invention the workpiece can be processed under a protective gas atmosphere or in a vacuum become.

Basically, it is sufficient if the electromagnetic radiation is aimed directly at the workpiece. The expediently electromagnetic radiation, however, by means of beam guidance means on the Workpiece directed.

In the aforementioned embodiment, the beam guiding means expediently uses a mirror whose reflection surface is too narrowed towards the workpiece.

A particularly advantageous development of the aforementioned embodiment provides that a mirror with a rotationally symmetrical, in particular a reflection surface that narrows conically towards the workpiece is used.

The invention is also based on the object of specifying a mirror, which in particular in a device according to the invention or a The method according to the invention can be used.

To solve this problem it is proposed that on the base body a funnel-shaped narrowing reflection surface is formed and that the Base body an insertion opening for inserting an object into the Has reflection area of the reflection surface.

The basic idea of this teaching is the reflection surface of the Mirror narrowing funnel-shaped, in particular conical.

The mirror according to the invention enables simultaneous processing a workpiece from several directions, for example a simultaneous one Machining a rotationally symmetrical workpiece via its entire scope. The mirror according to the invention is simple and inexpensive produced.

A further development of the mirror according to the invention provides that the Reflecting surface essentially rotationally symmetrical, in particular itself conically narrowing, is formed.

The insertion opening to the axis of rotational symmetry is expedient the reflection surface is essentially coaxial.

Fig. 1

zeigt eine Draufsicht auf eine erfindungsgemäße Ampullenfüll- und -verschließeinrichtung des getakteten Rundläufertyps.

Fig. 2

zeigt schematisch eine Seitenansicht der Einrichtung der Fig. 1 mit Anordnung des Rundläufers in einer Einhausung und außerhalb der Einhausung angeordnetem Laser.

Fig. 3

zeigt eine Variante der Einrichtung der Fig. 2 mit innerhalb der Einhausung angeordnetem Laser.

Fig. 4

zeigt eine weitere Variante der Einrichtung der Fig. 2 mit auf einem Einhausungsdach angeordnetem Laser.

Fig. 5

zeigt ein weiteres Ausführungsbeispiel einer erfindungsgemäßen Ampullenfüll- und -verschließeinrichtung des Rundläufertyps, wobei der Rundläufer kontinuierlich oder getaktet arbeiten kann.

Fig. 6

zeigt ein weiteres Ausführungsbeispiel einer erfindungsgemäßen Ampullenfüll- und -verschließeinrichtung des Rundläufertyps mit in den Rundläufer integrierter Strahlungsführungsanordnung, wobei es sich um eine kontinuierlich oder getaktet arbeitende Einrichtung handeln kann.

Fig. 7

zeigt ein Ausführungsbeispiel einer Ampullenfüll- und -verschließeinrichtung mit linearer Förderstrecke, wobei es sich um eine kontinuierlich oder getaktet arbeitende Einrichtung handeln kann.

Fig. 8

zeigt eine Variante der in Fig. 7 gezeigten Einrichtung.

Fig. 9

zeigt ein weiteres Ausführungsbeispiel einer erfindungsgemäßen Ampullenfüll- und -verschließeinrichtung, die zwei gesonderte Ampullen-Förderstrecken mit jeweiliger Füllstation und Verschließstation aufweist, wobei jeweils ein linearer Förderstreckenabschnitt entlang einer Laserstrahlungsstrecke verläuft.

Fig. 10

zeigt eine Variante der Einrichtung der Fig. 9.

Fig. 11

zeigt in Fig. 11a und Fig. 11b zwei weitere Varianten der Einrichtung der Fig. 9.

Fig. 12

zeigt ein weiteres Ausführungsbeispiel einer erfindungsgemäßgen Ampullenfüll- und -verschließeinrichtung des Rundläufertyps mit einer in den Rundläufer integrierten Laserstrahlführungsanordnung und einer einer gerade behandelten Ampulle zugeordneten Rückreflexionsanordnung zum Zurückreflektieren von von der Ampulle ausgehender Strahlung.

Fig. 13

zeigt die Rückreflexionsanordnung der Einrichtung der Fig. 12 im Detail.

Fig. 14

zeigt eine (ggf. auch als Rückreflexionsanordnung im Sinne der Anordnung der Fig. 13 dienende) Strahlführungsanordnung zur Bestrahlung einer Ampulle von mehreren Seiten mit Laserstrahlung ohne Notwendigkeit einer Ampullenrotation.

Fig. 15

veranschaulicht in den Teilfiguren Fig. 15a - Fig. 15h den Ablauf eines Ampullenbehandlungsprogramms ausgehend von einer im geschlossenen Zustand angelieferten Ampulle (Fig. 15a) bis zur nach Herstellung einer Einfüllöffnung befüllten und wieder verschlossenen Ampulle (Fig. 15h).

Fig. 16

zeigt eine Abwandlung des Verschließvorgangs entsprechend Fig. 15g mit Spießabzug.

Fig. 17

veranschaulicht das Verschließen einer Ampulle ohne Spießabzug.

Fig. 18

veranschaulicht das Verschließen einer Ampulle ohne Spießabzug durch Bestrahlung eines Ampullenhalses von mehreren Seiten mit Laserstrahlung unter mechanischer Einwirkung eines Behandlungsgases.

Fig. 19

veranschaulicht die Integration einer Wärmestrahlung rückreflektierenden Spiegelanordnung in eine Spießabzugsvorrichtung.

Fig. 20

veranschaulicht die Integration einer zur Bestrahlung eines Ampullenhalses von mehreren Seiten dienenden Spiegelanordnung in eine Spieß-abzugsvorrichtung.

Fig. 21

veranschaulicht in den Teilfiguren Fig. 21a - 21d mehrere denkbare Varianten für eine Intensitätsverteilung der auf einen Ampullenhals (Ampullenspieß) einwirkenden Laserstrahlung beim Vorerwärmen oder/und beim Verschließen.

Fig. 22

veranschaulicht das Beschriften einer verschlossenen Ampulle mit den Initialien "B + S" mittels eines Beschriftungslaserstrahls, der mittels einer Scanneranordnung über die Ampullenoberfläche geführt wird.

Fig. 23

zeigt ein Diagramm, das ein Beispiel für einen taktweisen Betrieb einer erfindungsgemäßen Ampullenfüll- und -verschließeinrichtung veranschaulicht.

Fig. 24

zeigt ein weiteres Diagramm zur Veranschaulichung eines Beispiels eines taktweisen Betriebes einer Ampullenfüll- und -verschließeinrichtung mit gegenüber dem Fall der Fig. 23 verdoppelter Verschließleistung (Zahl der pro Zeiteinheit verschlossenen Ampullen).

Fig. 25

zeigt ein Diagramm zur Veranschaulichung eines Beispiels eines kontinuierlichen Betriebs einer Ampullenfüll- und -verschließeinrichtung.

The invention and its various aspects are explained in more detail below with reference to several exemplary embodiments shown in the figures.

Fig. 1

shows a plan view of an ampoule filling and closing device according to the invention of the clocked rotary type.

Fig. 2

shows schematically a side view of the device of FIG. 1 with the arrangement of the rotary machine in a housing and a laser arranged outside the housing.

Fig. 3

shows a variant of the device of FIG. 2 with a laser arranged inside the housing.

Fig. 4

shows a further variant of the device of FIG. 2 with a laser arranged on a housing roof.

Fig. 5

shows a further embodiment of an ampoule filling and closing device according to the invention of the rotary type, wherein the rotary machine can work continuously or clocked.

Fig. 6

shows a further embodiment of an ampoule filling and closing device according to the invention of the rotary type with radiation guidance arrangement integrated in the rotary, which can be a continuously or clocked device.

Fig. 7

shows an embodiment of an ampoule filling and closing device with a linear conveyor line, which can be a continuously or clocked device.

Fig. 8

shows a variant of the device shown in Fig. 7.

Fig. 9

shows a further embodiment of an ampoule filling and closing device according to the invention, which has two separate ampoule conveying sections with respective filling station and closing station, each with a linear conveying section section running along a laser radiation section.

Fig. 10

shows a variant of the device of FIG. 9.

Fig. 11

11a and 11b show two further variants of the device of FIG. 9.

Fig. 12

shows a further embodiment of a vial filling and closing device according to the invention of the rotary type with a laser beam guidance arrangement integrated in the rotary vane and a back reflection arrangement assigned to a just treated ampoule for reflecting back radiation emanating from the ampoule.

Fig. 13

shows the back reflection arrangement of the device of FIG. 12 in detail.

Fig. 14

shows a beam guiding arrangement (possibly also serving as a back reflection arrangement in the sense of the arrangement in FIG. 13) for irradiating an ampoule from several sides with laser radiation without the need for ampoule rotation.

Fig. 15

15a-15h illustrates the sequence of an ampoule treatment program starting from an ampoule delivered in the closed state (FIG. 15a) up to the ampoule which has been filled and closed again after a filler opening has been made (FIG. 15h).

Fig. 16

shows a modification of the closing process according to Fig. 15g with skewer trigger.

Fig. 17

illustrates the closure of an ampoule without a skewer trigger.

Fig. 18

illustrates the sealing of an ampoule without deduction by irradiating an ampoule neck from several sides with laser radiation under the mechanical action of a treatment gas.

Fig. 19

illustrates the integration of a heat radiation retroreflective mirror arrangement in a spit extraction device.

Fig. 20

illustrates the integration of a mirror arrangement for irradiating an ampoule neck from several sides into a skewer trigger device.

Fig. 21

21a-21d illustrates several conceivable variants for an intensity distribution of the laser radiation acting on an ampoule neck (ampoule spit) during preheating and / or during closing.

Fig. 22

illustrates the labeling of a sealed ampoule with the initials "B + S" by means of a labeling laser beam which is guided over the surface of the ampoule by means of a scanner arrangement.

Fig. 23

shows a diagram illustrating an example of a cyclical operation of an ampoule filling and closing device according to the invention.

Fig. 24

shows a further diagram to illustrate an example of a cyclical operation of an ampoule filling and closing device with a doubling of the sealing performance compared to the case of FIG. 23 (number of ampoules sealed per unit of time).

Fig. 25

FIG. 12 is a diagram illustrating an example of a continuous operation of an ampoule filling and closing device.

Fig. 26

in schematischer, teilweise geschnittener Seitenansicht ein erstes Ausführungsbeispiel der erfindungsgemäßen Einrichtung mit einem ersten Ausführungsbeispiel des erfindungsgemäßen Spiegels,

Fig. 27

eine Draufsicht auf den Spiegel gemäß Fig. 26,

Fig. 28

in gleicher Darstellung wie Fig. 26 ein zweites Ausführungsbeispiel der erfindungsgemäßen Einrichtung, wobei die Mittel zur Erzeugung elektromagnetischer Strahlung und die Positioniereinrichtung nicht dargestellt sind,

Fig. 29

in gleicher Darstellung wie Fig. 28 ein drittes Ausführungsbeispiel der erfindungsgemäßen Einrichtung und

Fig. 30

ein zweites Ausführungsbeispiel des erfindungsgemäßen Spiegels.

Furthermore, FIGS. 26 to 29 show several exemplary embodiments of a device for machining a workpiece, in particular an ampoule, by means of electromagnetic radiation, in which electromagnetic radiation, in particular laser radiation, is directed onto the workpiece to be machined from at least two directions. It shows in detail:

Fig. 26

a schematic, partially sectioned side view of a first embodiment of the device according to the invention with a first embodiment of the mirror according to the invention,

Fig. 27

26 shows a plan view of the mirror according to FIG. 26,

Fig. 28

26 shows a second exemplary embodiment of the device according to the invention, the means for generating electromagnetic radiation and the positioning device not being shown,

Fig. 29

in the same representation as FIG. 28, a third exemplary embodiment of the device according to the invention and

Fig. 30

a second embodiment of the mirror according to the invention.

In the following description of the various embodiments unless otherwise expressly stated, for identical, analog or corresponding components are the same Reference numerals used, from embodiment to embodiment by a small letter starting with a in alphabetical order Order are added. Only the differences to Embodiment already described above or the previous already described embodiments; otherwise reference is expressly made to the preceding description.

1 shows an ampoule filling and closing device according to the invention of the rotary type with a rotating rotor 12a, which is designed for conveying ampoules along an arcuate conveyor section 16a. Ampoules which have an ampoule filling opening are fed to the rotary machine via a feed conveyor section 14a. Along the circular arc-shaped conveyor section 16a, the ampoules 18a, which are arranged equidistantly along the circumference of the rotor 12a, are set in rotation about a longitudinal axis of the ampoule (vertical axis) by suitable drive means, as indicated by the arrow 20a. Of course, the ampoules only need to be set in rotation where this is desired or necessary with regard to ampoule processing. The rotor 12a rotates clockwise counterclockwise (arrow 22a) in each case according to an angle of rotation which corresponds to the circumferential distance of two ampoules immediately following one another. Fig. 1 shows the ampoules in their position, which they take up when the rotor 12a is currently stationary. For each delivery cycle of the rotor 12a, the ampoules 18a are moved one position further. In this way, the ampoules are first moved to a filling station 24a and then to a closing station 26a. The closing station is assigned an infrared laser 28a (in the present case a CO ₂ laser), the laser beam 30a of which is divided by a beam splitter 32a into a first partial beam 34a and a second partial beam 36a. The first partial beam 34a is deflected in the direction of the rotor 12a by means of a deflecting mirror 38a serving as beam guiding means. There it meets an already filled ampoule 40a in a conveying position corresponding to a stationary rotor 12a in order to preheat the ampoule before the actual closure, so that air or protective gas introduced into the ampoule can be heated and can escape in accordance with the heat-related expansion. The first partial beam 34a falls through a lens 42a serving as beam shaping means, the lens 42a also being able to be formed by a special lens arrangement or the like. In this respect, the lens 42a symbolizes a beam shaping arrangement in the most general sense.

With the next funding cycle, it reaches as shown in FIG. 1 ampoule 40a preheated by partial jet 34a a conveying position, in that the second partial beam 36a hits the ampoule. The second too Partial beam 36a previously passes through a lens serving as beam shaping means 44a through, the lens 44a again for a lens arrangement or Beam shaping arrangement can stand. By preheating the The gas in the ampoule was able to adequately measure the first partial jet escape and the ampoule could absorb sufficient thermal energy, so that now the ampoule through the second sub-beam 36a can be easily melted to seal them. In which 1 is completed by closing, that a skewer trigger 46a has an ampoule skewer withdraws. Alternatively, the closure can also be done without removing one Ampoule spit solely by the action of the second sub-beam 36a take place, with additional processing on softened sections of the Ampoule neck can be directed to by mechanical action bleeding / collapse of ampule wall material, herein Case glass, promote.

After closing by the closing station 26a, the Ampoule first through the rotary machine 12a and then over a discharge conveyor 48a transported away, for example to a packaging station. If desired, the ampoule can be transported through the discharge conveyor 48a can be provided with a label by a labeling station or labeled by a labeling or / and marking station or / and be marked.

Optionally, the ampoule filling and closing device of FIG. 1 can also be designed for ampoules manufactured in the closed state, i.e. fill ampoules without an open filler opening. For this, a second infrared laser 50a can be provided, which has a laser beam 52a generated. This laser beam 52a is turned in by means of a deflection mirror 54a Directed to the rotor 12a, such that it by a beam shaping means serving lens 56a (which in turn is for a lens or Beam shaping arrangement) hits a respective ampoule 58a, the two conveying positions are arranged in front of the filling station 24a. By This laser beam 52a creates an ampoule fill opening through which then in the filling station 24a the filler (for example a pharmaceutical) is filled into the ampoule. A separate second laser is not necessary if using a beam splitter laser light from the Lasers 28a is used for ampoule opening.

The laser beams hit during the rotational movement of the rotor 12a of the laser 28a or the laser beam of the laser 50a onto no ampoule since only fixed beam guidance is provided in this embodiment. You can therefore use the lasers during the funding cycle of the facility switch off or - preferably - a shutter arrangement or laser beam trap arrangement operate so that the laser beams do no damage can. You can also - this is probably the simplest solution - the rotor simply form around its circumference as a beam trap so that the laser beams are not reflected back by the rotor and accordingly none uncontrolled back reflections are to be expected. For high operational reliability and a high level of personal protection is switching on and off of the laser or actuation of an additionally provided shutter or beam trap arrangement preferred.

Fig. 2 illustrates how the ampoule filling and closing device of the Fig. 1 could be arranged. The rotor 12b is with the ampoules 18b and the filling station, the closing station and, if applicable, the ampoule opening station (not shown in FIG. 2) arranged in a housing 70b. The Housing 70b forms a shielding chamber that also acts as an insulator can be designated. For high demands on sterility and The housing 70b can be provided with a feed device 72b for purity purified air, which is symbolized by arrows 74b Laminar flow created inside the shield chamber 70b. Since the Laser radiation 30b for a targeted and defined heating of the Ampoules 18b during preheating or closing is used, there is no removal of heat from the inside of the shielding chamber required so that laminar air flow 74b does not is disturbed. Alternatively, you could use a shielding chamber provide a protective gas atmosphere instead of purified air contains.

In the arrangement shown in Fig. 2, the laser 28b is outside the Housing 70b on a support table 76b, possibly an optical table 76b, stored and the laser radiation 30b is by one for the laser radiation transparent window 78b into the interior of the housing 70b, that is, into the interior the shielding chamber. This points compared to that in FIG Alternative shown arrangement of the laser inside the housing great advantage that the laser for adjustment and maintenance work is accessible without the risk of dirt or germs in the Shielding chamber can be introduced. If so, you can Clean room conditions of the highest quality inside the Maintain housing 70b without maintenance and adjustment work are difficult on the laser. It is particularly advantageous if you use the laser not only outside the enclosure 70b but even in a neighboring room arranges, for example a washroom or the like, whereas the ampoule filling and closing device together with its Enclosure in a room higher than the neighboring room Air quality is arranged.

The embodiment of FIG. 3, except for the arrangement of the laser 28c and the size of the housing 70c in the embodiment of FIG. 2 corresponds, but otherwise shows a space-saving arrangement of the Laser, namely an arrangement of the laser with a vertically arranged Laser axis. Accordingly, one serving as a beam guiding means Deflecting mirror 80c is provided, which in the vertical direction downwards redirecting propagating laser beam 30c by about 90 °.

Another space-saving arrangement of the laser is illustrated in FIG. 4. Here the laser 28d is arranged on a roof of the housing 70d, outside the shielding chamber. The laser radiation 30d is down through a first deflecting mirror 82d by approximately 90 ° redirected, then falls through a window 78d and is then through a second deflection mirror 80d deflected by about 90 °, then by a Beam guide arrangement 42d / 44d on the ampoule to be processed in each case 18d to fall.

Another embodiment of an ampoule filling according to the invention The rotary type and sealing device of the rotary type is illustrated in FIG. 5. With this device (filling station, opening station provided if applicable and any skewer extraction device provided is not shown) is a Swivel mirror 90e is provided as a beam guiding means, which serves to to vary a deflection angle for the laser beam 30e. There are more options:

A variant would be that the rotary machine 12e is similar to the rotary machine of the The above-described exemplary embodiment operates intermittently, whereby the laser beam 30e by means of the swivel mirror 90e between one for Pre-heating beam guidance (deflection angle α ') and one for beam sealing actually used (deflection angle α) is switched. However, this variant is due to relatively high Dead times for ampoule processing less preferred.

Another variant is that the rotary machine 12e works in cycles, but that the preheating during transportation of the ampoule from one first conveying position corresponding to a stationary rotor 12e and a subsequent second rotor 12e corresponding to a stationary one Conveying position takes place with the corresponding tracking of the laser beam by correspondingly pivoting the pivoting mirror 90e. The The laser beam is, for example, continuous from a deflection angle α 'corresponding beam guidance until reaching a Deflection angle α corresponding beam guidance according to the conveying movement the currently processed ampoule. Has the ampoule got it through 5 reaches the ampoule 92e symbolized in FIG. 5, the remains Rotor 12e stand and the beam guidance given by the deflection angle α remains until the ampoule is melted and sealed, if necessary, pulling off an ampoule skewer. The one provided for this purpose Skewer trigger device can be stationary, since it withdraws the respective ampoule skewer when the ampoule is at a standstill.

Another variant is that the rotary machine 12e works continuously, thus revolves continuously at constant speed. In one In such a case, the preheating takes place and the actual closing takes place by melting using the laser radiation with a moving ampoule. All organs acting on the ampoule, e.g. filling needles, gassing needles and skewer trigger links (if skewers are to be removed) is) must be trained accordingly for moving Ampoules to act on them. With regard to the effect of laser radiation the training of the Means be such that from a deflection angle α 'to the deflection angle α preheating the ampoule and that from Deflection angle α up to a deflection angle α "the actual closing he follows. After reaching the deflection angle α ", the swivel mirror pivots 90e back again, so that again by the deflection angle α ' given beam guidance is reached. The for exact tracking required pivoting speed of the deflection mirror 90e during the Tracking is not exactly constant, but on the non-linear Orbital movement of the ampoules coordinated. For larger distances of the Deflecting mirror 90e from rotor 12e can also be a constant one Swing speed sufficient, since this is a sufficiently good Approximation for the actual orbital movement of the ampoules.

It should also be mentioned that during the preheating and the actual Closing different laser powers can be set can. One can during the preheating and the actual But also work with the same laser power.

A preferred development of the embodiment shown in FIG. 5 according to the previous description provides that a detector arrangement 94e is provided by ampoule 92e at the end of preheating outgoing radiation, in particular heat radiation, possibly also on Relaxation of states in the Ampule wall material declining emission radiation (one speaks also detected by a so-called "process lights") and a corresponding one Detection signal 96e of an assigned control unit 98e supplies. The control unit 98e serves on the one hand to control the rotary device 12e by means of a control signal 100e and on the other hand to Controlling the laser 98e by means of a control signal 102e.

The control unit 98e can derive a current one from the detection signal 96e Treatment status of the preheated ampoule 92e, in particular determine their temperature and calculate how much Energy of the ampoule during the closing phase using the Laser radiation 30e is to be supplied. According to this calculation result is the laser 28e for the closing phase with regard to its Power set. This makes it easy to change Ampoule formats or ampoules with larger tolerances regarding the Edit ampoule geometry, wall thickness and the like, i.e. fill and close without having to sort the ampoules beforehand with appropriate setting of the process parameters depending on the sorting. Rather, these process parameters can be based on the acquisition of the treatment state is automatically set by the detector 94e become.

If relaxation emission radiation is to be recorded, it is recommended that the detector in deviation from the illustration in the figure on the below to arrange the side of the ampoule exposed to the action of the laser light, so that this "process lighting" can hit the detector undamped.

It should also be mentioned that instead of an inpatient, only the treatment status at the end of the preheating detector 94e with the ampoule under the influence of the laser radiation co-moving detector can be provided, which continuously Treatment status of the ampoule recorded and accordingly a Continuous control or regulation of the process parameters enables.

Another embodiment of an ampoule filling according to the invention and sealing device is shown in Fig. 6. It is again about an ampule filling and closing device 10f of the rotary type, which with regard to their basic structure, the embodiment of FIG. 1 corresponds and also in the example case assumed here clockwise is working. A major difference is that preheating during the transport of the ampoule from a conveying position immediately before the one corresponding to the stationary skewer trigger device 46f Conveying position to this latter, the skewer trigger device 46f corresponding funding position. The laser radiation 30f des Laser 28f is directed in such a way that it is guided by the beam shaping means 44f (Lens 44f) meets the ampoule that is currently in the area of influence of the skewer device 46f. This currently stopped Ampoule is melted by the laser radiation 30f until then finally the ampoule skewer is withdrawn by the extraction device 46f becomes. By pulling off the ampoule skewer for the laser beam 30f clear the way to continue propagating in the laser beam direction until it hits a Mirror facet wheel 110f falls, which is fastened coaxially to the rotor 12f and rotates with the rotor 12f. The laser beam falls on one Mirror facet shaped such that the laser beam 30f is directed toward is diverted to the next ampoule to be sealed (dashed line Section 112f of the laser beam 30f). This applies to every rotary position of the Rotors 12f during the transport of this ampoule until it reaches the Spit deduction conveying position. The mirror facet wheel 110f (depending on Training can also be called a polygon mirror arrangement) thus serves to continuously track the laser beam 30f with its Beam section 112f during preheating. After all, it is Spit withdrawal point reached, the conveyor rotor 12f stops and the Laser radiation 30f hits the ampoule directly to melt it, until finally the skewer is pulled off and the laser radiation again meets the following ampoule.

As a modification of the previous description, it is also possible, also the melting, i.e. the actual closing, at perform moving ampoule, for which purpose the conveyor rotor 12f continuously and preferably rotates at a constant rotational speed. To do this would have to in the event of a skewer pulling the skewer pulling member according to the Move the ampoule movement with the ampoule; the same applies to others Organs, such as filling needles and fumigation needles. The laser radiation 30f would in this case only in exactly one momentary position of the straight one processed ampoule directly onto this and otherwise over the Mirror facet wheel 110f can be deflected towards the ampoule.

It should also be mentioned that the facets of the mirror facet wheel 110f are one special form to be calculated in detail in order to to achieve the described redirection. The representation in Fig. 6 is so far simplified.

Fig. 7 shows an embodiment of an ampoule filling according to the invention and closure device 10g with a linear ampoule conveyor. The facility is designed to treat four ampoules simultaneously, i.e. fill four ampoules, preheat four ampoules and four Seal ampoules by pulling an ampoule skewer. This is a laser arrangement 28g is provided which emits four laser beams 30g. The Laser arrangement 28g can be from a laser with a subsequent beam splitter arrangement be formed or by four separate lasers. Furthermore, one Filling station 24g provided with four filling heads 25g and a closing station 26g with four skewer trigger links 46g. It can be an in with regard to the ampoule conveyance working continuously or intermittently Act establishment. It is hereinafter referred to as a continuous Out of operation. The four laser beams 30g are through one pivotable facet mirror element (or - alternatively - a rotating mirror element, about a mirror wheel) towards the moment redirected ampoules to be preheated or melted. The Facet mirror element continuously pivots clockwise according to the forward movement of the ampoules until it is withdrawn the ampoule skewers in the opposite direction with the largest possible Swiveling speed swings back to the next ampoules with To irradiate laser radiation. (In the case of a rotating mirror element this could alternatively continue to rotate in the same direction.) This Ampoules are moved along the conveyor line as they advance first preheated and then finally melted until the Skewer trigger elements are used. Skewer extractors and filling heads must match the ampoules as they move forward move with it. However, cyclical operation is also easily possible with stationary filling heads and stationary skewers, where but preferably the preheating during transportation of the ampoules to the skewer trigger organs.

The principle of tracking or deflection illustrated in FIG. 7 several laser beams for simultaneous processing (preheating or / and melting) of ampoules can also be used with other geometries and courses of the ampoule conveying path (for example in the case of a circular arc). Is a swivel or rotatable facet mirror element is provided, the swivel / Rotational movement and the geometry of the mirror facets on the conveying speed and the course of the conveyor line can be coordinated. The Geometry of the mirror facets or the general formation of a The mirror arrangement can correspond to the tasks of the facet mirror element or the mirror arrangement are calculated and is in the Usually deviate from the simplified representation shown in FIG. 7.

It should also be emphasized that preheating of closable Ampoules are not absolutely necessary, but only for a closure with short laser exposure times is very advantageous. In the Description of FIG. 7 was assumed that a Preheating is provided (which is for a different pivot position of the Facet mirror element 112g resulting beam guidance for preheating of ampoules is indicated by dashed lines), such preheating is but - as I said - not mandatory. One can melt the Also carry out ampoules in such a way that the ampoule is heated in such a way takes place that the air contained in the ampoule or that in the ampoule contained gas (in particular protective gas) is heated and accordingly expands before it converges to ampoule wall material and if necessary, the skewer is removed. So you become the power of laser beams according to the ampoule geometry and wall thickness vote so that the ampoule does not heat up too quickly. at such a constellation with continuous exposure to laser radiation it is arbitrary if you consider a particular phase of laser exposure Preheating phase and another laser exposure phase as Capping phase. In any case, it can serve as a preheating phase that part of the laser beam exposure phase are designated in which no ampoule wall material is melted yet. This "preheating phase" must be long enough to contain the ampoule Gas is heated and according to its temperature-related expansion can escape from the ampoule before it becomes essential Congestion / collapse of ampoule wall material comes and at least before - if provided - the respective ampoule skewer removed becomes.

Fig. 8 shows a variant of the embodiment of Fig. 7 for higher Filling and closing performance (number of filled and closed per unit of time Ampoules). The laser array 28h creates eight parallel ones Laser beams 30h and the filling station 24h with eight filling heads 25h only four of which are shown. The capping station is 26h executed with eight skewer trigger links 46h. Unless you have the facility 10h operates in such a way that a separate preheating phase is identifiable, it takes place in one go with the melting and subsequent skewer removal. Accordingly, in contrast to Embodiment of FIG. 7 no ampoules between those in the area of influence the filling station 24h and in the area of influence of the skewer trigger arrangement 26h standing ampoules arranged, but on the in the area of influence the ampoules 114h standing 24h follow in the conveying direction immediately those standing in the area of influence of the skewer trigger arrangement 26h Ampoules 116h. In contrast, in the embodiment of FIG. 7 between the ampoules standing in the area of influence of the filling station 24g 114g and those standing in the area of influence of the skewer trigger arrangement 26g Ampoules 116g four ampoules 118g arranged according to the preferred Variant must first be preheated before they are in reach the area of influence of the skewer trigger arrangement 26g. As well as in the case of device 10g of FIG. 7, device 10h may be referenced work cyclically or continuously on ampoule delivery. Is too it is possible for both embodiments that in deviation from the Representation of the conveyor line is not linear, but curved, for example follows an arc.

A very advantageous embodiment of an inventive Ampoule filling and closing device 10j is shown in FIG. 9. The Device 10j has two separate ampoule conveying lines 16j-1 and 16j-2, each with a filling station 24j-1 or 24j-2 and a closing station 26j-1 and 26j-2 (each with a skewer trigger, preferably in the form of a skewer puller).

The ampoule conveying sections transport the ampoules 18j-1 and 18j-2 16j-1 and 16j-2 are formed by linear conveyor sections and are designed for cyclical delivery of the ampoules (the filling organs, Spit trigger organs and other ampoule treatment organs are therefore designed to treat stationary ampoules).

Significant advantages result from the fact that a conveyor section 120j-1 or 120j-2, which is between the on the filling conveyor position extends the following conveying position and the skewer withdrawal conveying position, runs parallel and along a laser radiation path, the Ampoule or the ampoules in this conveyor section are arranged or along this conveyor section move under the influence of laser radiation. Like Fig. 9 reveals that the ampoules 18j-1 and 18j-2 are first after filling in the conveyor section 120j-1 or 120j-2 and thus in the laser radiation propagating along the laser radiation path moved and after removing the respective ampoule skewer leads Conveyor the ampoules again out of the area of influence Laser radiation out when the respective ampoule reaches the conveyor section 120j-1 or 120j-2 leaves and in the subsequent conveyor section 122j-1 or 122j-2 occurs. Switching the Laser radiation between different laser radiation paths or a Tracking or swiveling laser radiation is part of this training the device is not necessary because the ampoules move during their movement along the conveyor section 120j-1 or 120j-2 are inevitably always under the influence of laser radiation. This The feature of the device shown in FIG. 9 is in particular also for one Continuous conveyor operation without a conveyor cycle is advantageous because then a Tracking the laser radiation according to the movement of the ampoules eliminated. A variant of the exemplary embodiment, not shown separately 9 is therefore characterized by continuous conveyor operation, for this purpose the ampoule treatment organs are designed in this way have to move with the ampoules. For example the skewer trigger elements along the on the central conveyor section 120j-1 or 120j-2 following conveyor section 122j-1 or 122j-2 or along the central conveyor section 120j-1 or 120j-2 move with the ampoules, whereas the filling organs along the line preceding section 120j-1 or 120j-2 Conveyor section 124j-1 or 124j-2 with the ampoules could move along. It should also be mentioned that the course of the Conveyor routes, especially the sudden changes in direction of the "angular" formation of the conveying paths which require the supported ampoules, has purely exemplary character; you can easily in the straight sections 120j-1 and 120j-2 merging, curved Provide feed and discharge conveyor sections.

In addition to FIG. 9, it should be added that a friction wheel arrangement 126j is provided is to the ampoules while interacting with the Laser radiation continuously rotates around its respective longitudinal axis to let. The laser radiation is generated by two lasers 28j-1 and 28j-2, whose laser beams 30j-1 or 30j-2 by means of a beam splitter 32j-1 or 32j-2 is divided so that after deflecting one of the respective partial beams by means of a deflection mirror 38j-1 or 38j-2, two each parallel rays are created, one with the Ampoules in the conveyor section 120j-1 and the other with the Ampoules interact in the conveyor section 120j-2. By a slight angular misalignment between those of the 28j-1 laser partial beams and partial beams from the 28j-2 laser prevents the laser radiation emanating from the one laser enters the other laser and thus interferes with the operation of the laser.

The position of the ampoules shown in FIG. 9 is that of the laser 28j-2 outgoing laser radiation for preheating the ampoules that are in the representation of the figure at the left end of the conveyor sections 120j-1 and 120j-2 are arranged and those from the laser 28j-1 Partial beams are used to close the sections at the right end of these conveyor sections arranged in the area of the skewer trigger elements Ampoules by melting the ampoules with subsequent skewer removal. During the promotion of the left end of the conveyor sections arranged ampoules over this conveyor section to right end is only this one ampoule in the named Conveyor section arranged so that this ampoule of both Sides is irradiated with laser radiation, namely on the one hand with a Partial beam of the laser 28j-1 and on the other hand with laser radiation from the laser 28j-2. This results in a correspondingly increased energy supply to the Ampoules during transport along the conveyor section 120j-1 or 120j-2.

It should also be added that the beam splitters 32j-1 and 32j-2 are preferred have a division ratio of 50%: 50%, so for the conveyor sections 120j-1 and 120j-2 have the same conditions. The radiation power emitted by lasers 28j-1 and 28j-2 can but differ between the two lasers. For example, in the case a pulsed delivery of the lasers 28j-2 significantly less power than the laser 28j-1 will emit if during the preheating compared to the actual melting, less energy is supplied to the ampoules should.

The embodiment of FIG. 10 differs from the embodiment 9 only in that the ampoule filling and closing device 10k of FIG. 10 is only equipped with a laser 28k. This Laser is used both for preheating and for actual melting of the ampoules, the am right end of the conveyor section 120k-1 and 120k-2 arranged Ampoule the laser radiation to the next one, at the left end of this Conveyor section section arranged ampoule is passed and irradiated for preheating.

The embodiment of FIG. 11a differs from the embodiment 9 in that the length of the conveyor sections 1201-1 and 1201-2 is doubled, so that there are always at least two and a maximum of three (shown in Fig. 11) ampoules in each Conveyor route section 1201-1 and 1201-2 are located along a Laser radiation path runs. In the situation shown in Fig. 11 are arranged at the left end of these conveyor sections Ampoules irradiated by laser radiation from laser 281-1 to the ampoules preheat. Arranged at the right end of the conveyor sections Ampoules are irradiated with laser radiation from the 281-2 laser close the ampoules by melting and then removing the skewer close. The in the middle of the respective conveyor section arranged ampoules are currently not under the influence of Laser radiation. This is advantageous in so far as preheating does serves that the air contained in the ampoule or that in the ampoule to heat contained gas and to give it time, according to the temperature-related expansion to emerge from the ampoule. Since that Melting down does not immediately follow preheating is sufficient Time provided that a temperature compensation between preheated Wall material and gas contained in the ampoule can take place and that expanding gas can escape from the ampoule before the ampoule is closed.

In the design of the device 101 shown in FIG. 11a, the Ampoules always irradiated with laser radiation from one side only, namely from left for preheating and right for melting.

11b shows a modification of the embodiment of FIG. 11a. According to the modification, again - similar to the case in FIG. 9 - Always one or two ampoules in the central one, facing the laser beam path parallel conveyor section, the time interval, while an ampoule is irradiated from two sides is minimized. Compared to the example of Fig. 11a is a dead time during which one in central ampoule section arranged ampoule no laser radiation received, avoided, which has the advantage that a derivation / Radiating thermal energy from the preheated section of the Ampoule can not occur during such a dead time, so that for the Melting less energy must be supplied or less Laser power is sufficient for preheating.

Another embodiment of an ampoule filling and closing device 10m of the rotary type is shown in FIG. Here is one Relatively compact arrangement achieved in that the laser radiation of the Laser 28m from the inside of the rotor 12m is supplied. A corresponding Beam guidance arrangement is indicated at 130m. The in Fig. 12 illustrated design principle can be used for both clockwise working machines as well as for continuously working machines (cyclically and continuously with regard to the promotion of the ampoules) be applied. In particular, can be integrated into the rotor Laser beam guidance and a tracking of laser radiation accordingly an ampoule movement as well as a stationary laser beam guidance comparatively simple way can be realized.

The embodiment of FIG. 12 is characterized in that the ampoule currently under the influence of laser radiation 132m is assigned a radiation reflection arrangement 134m which is emitted by the Ampule 132m outgoing radiation, especially reflected laser radiation and heat radiation, reflected back to the ampoule. It becomes this refer to Fig. 13, which shows a reflection mirror 134n which is related to is positioned and formed on an ampoule 132n such that the Ampoule 132n radiated heat radiation 136n reflected back to the ampoule becomes. Furthermore, laser radiation reflected by the ampoule 132n 138n reflected back to the ampoule 132n. Through this back reflection from laser radiation and heat radiation to the ampoule Energy of the laser radiation to a high degree for preheating or / and Melting of the respective ampoule used, so that correspondingly short Exposure times for the laser radiation are possible.

14 shows a variant, similar to a radiation reflection arrangement the arrangement 134m or 134n can be used to create an ampoule To irradiate 132p from several sides, so that the Ampoule becomes dispensable. For this purpose, the laser beam 30p is expanded in such a way that that a substantial part of the laser beam past the ampoule 132p goes. This part of the laser radiation passing the ampoule strikes the radiation reflecting assembly 134p and is directed therefrom toward Ampoule 132p deflected, so that this from all sides with laser radiation is irradiated. At the same time, the reflection arrangement can be similar to that in 13 reflect radiation from the ampoule back to the ampoule.

It should be noted that in the representation of Figures 13 and 14 only for reasons of simplification, a spherical shape of the reflection surface of the mirror 134n or 134p was selected. To optimize the The mirror can also have properties of the mirror 134n or 134p an aspherical reflective surface. An optimization the reflection surface with regard to those to be fulfilled by the mirror Tasks are no problem for the specialist.

15 illustrates a machining program for opening, filling, Preheat and close an ampoule. 15a shows an ampoule in the closed state as it is manufactured by the manufacturer. 15b shows how the ampoule using laser radiation 52q while rotating the ampoule is opened around its longitudinal axis. The laser radiation is 52q used to remove an upper ampule tip, so that eventually an ampoule with an ampoule fill opening is provided, as in Fig. 15c is shown. If ampoules are used, an ampoule fill opening from the outset 15c represents the starting point for the treatment program.

Figure 15d illustrates filling the ampoule using a Filling needle. Shielding gas can also enter the Ampoule are introduced, for example by means of a separate Fumigation needle or with a filling channel and a fumigation channel having treatment needle.

15e, the ampoule is completely filled and must now be closed become. For this purpose, the ampoule according to 15f is first placed in a middle one Height range of their ampoule skewer 19q irradiated with laser radiation 34q, the ampoule rotating about its longitudinal axis. If desired, can the ampoule continues to be fumigated; a corresponding fumigation needle, which can be mirrored, for example, is shown in FIG. 15f. This Fumigation needle dips through the entire ampoule spit 19q to upper end of the cylindrical receiving space of the ampoule in the ampoule on. Because during the preheating the fumigation on this extremely effective way can be continued in a conventionally often required final fumigation immediately before Closing the ampoule can be dispensed with. But you can also get one Provide final fumigation, the final fumigation in an initial phase of closing even by means of an ampoule stick needle can be immersed in the ampoule. This needle just has to pulled out in time before it converges / collapses comes from melted ampoule wall material and especially before the ampoule skewer is pulled out, if one Skewer removal is provided at all.

15g shows the removal of the ampoule skewer by means of a skewer puller, after the ampoule has previously been melted by means of the laser beam 36q has been. Since after removing the ampoule skewer the laser beam 36q is no longer intercepted by the ampoule, a beam trap is 140q indicated on which the laser radiation 36q after pulling off the ampoule skewer meets. To promote detachment of the ampoule stick from the actual ampoule, in particular to interrupt a possibly forming material thread (glass thread) between ampoule and withdrawn Spit, the laser beam 36q can be pivoted upwards around it To melt the thread in a targeted manner. 15h then shows the completely closed one Ampoule.

In Fig. 15g, the laser beam was indicated in accordance with the dashed line Variant pivoted upwards, for example by a corresponding one Swivel mirror. However, passive beam guidance is also possible, that leads to the same goal. This is shown in Fig. 16. Here is behind the Ampoule 18r provided a mirror 142r, which is removed after removing the ampoule skewer deflects the laser beam 36r upwards so that it is directed onto the Thread between the withdrawn ampoule skewer and the actual ampoule hits and thus promotes the interruption of this thread. Again is one Beam trap 140r indicated, which reliably prevents the laser beam Causes damage.

Another variant is indicated in FIG. 17. The one shown in FIG Ampoule is an ampoule that can be removed without skewer is closed. Opening (if closed ampoules are used filling) and preheating (if necessary with ampoule fumigation) can with such an ampoule analogous to that in Figures 15a to 15f illustrated procedure. To close the The ampoule is now in its upper area adjacent to the insertion opening irradiated with a laser beam 36s until the ampoule wall material (in In the present case, glass) merges or collapses and the Ampoule opening closes. The one preceding the closing Ampoule preheating was also preferably done using one of these upper wall area of the ampoule irradiating laser beam instead; it is but also conceivable, a height difference between the zone of influence Laser radiation for preheating and the zone of influence To provide laser radiation for melting. (The latter also applies to the Case that the ampoule is closed by pulling a skewer.)

Especially in the case of larger ampoule filling openings, it can be advantageous, the collapse and convergence of the melted To promote ampoule wall material by mechanical action. For this purpose, a nozzle arrangement 150s with an upper one is shown in broken lines in FIG Nozzle 152s and a lower nozzle 154s indicated, each one Machining gas jet 156s or 158s on the top, under the action the area of the ampoule 18s that is aligned with the laser radiation 36s. The processing gas jets hit the melted wall material and exert forces on it that reliably converge and collapse of the wall material without capillary formation. The The end result after successfully closing the ampoule is then the same essentially again the cash position of FIG. 15h.

It should be emphasized that those shown in Figures 15 and 16 Ampoule formats are only exemplary and that too any other ampoule formats, in particular with a different volume and other form can be used.

In the exemplary embodiment in FIG. 17, the laser radiation 36s only strikes one side of the ampoule so that it their longitudinal axis rotates (arrow 20s). An embodiment variant without Ampoule rotation is shown in Fig. 18. Here is one for Longitudinal ampoule axis symmetrical deflection mirror 170t provided, which in Laser beam 36t deflected longitudinal ampoule axis deflected such that the Ampoule 18t, of which only one ampoule neck is shown, in the upper one End area of the ampoule neck irradiated with laser radiation from all sides becomes. A processing gas nozzle arrangement 150t is located in the mirror 170t integrates a plurality of machining gas jets 156t from all Directions to the end region of the beam irradiated by the laser radiation Ampoule neck aligned. For this purpose there is an annular channel for the processing gas in integrates the mirror 170t, a plurality of which are to openings in the Branch channels leading mirror surface branches. A machining gas source 172t is indicated schematically. To the processing gas is still too mention that in the case of gassing the ampoules with protective gas Shielding gas can also be used as a processing gas.

It should also be mentioned that excellent, ampoule caps closing the ampoules can be reached, such as this is indicated in dashed lines in FIG. 18, the use of Machining gas is not mandatory but is helpful. This should be because that the effect of the laser radiation exactly in terms of power and Intensity distribution can be adjusted so that an optimal adjustment of the Process parameters on the respective ampoule is possible. If from excellent crest is spoken, so this is particularly meant that the closed ampoule in the area of the top has sufficient material thickness and none when cold significant tensions occur. It will be a good mechanical one Resilience of the fused ampoule heads is achieved by various tests (e.g. knock test, pliers tear tests) can be demonstrated.

19 illustrates the integration of a radiation reflection arrangement according to the arrangement of FIG. 13 and / or FIG. 14 in a Spit off device. The ampoule neck or ampoule spike is shown an ampoule 18u, which is in the area of influence of a skewer forceps 46u located. The skewer trigger pliers are made in two parts with skewer trigger pliers parts, which are movably mounted according to the arrows 180u. The ampoule spit is engaged with the spit puller 46u; it only has to be moved upwards to pull off the ampoule skewer, as soon as the ampoule spit is adequately exposed to the laser radiation 36u has melted.

In a lower end area, the skewer puller is with two for Provided ampoule spit coaxial mirrors 134u-1 and 134u-2, that for the back reflection of radiation emanating from the ampoule spit (reflected laser radiation and / or heat radiation). The laser radiation 36u enters through an opening 132u in the mirror 134u-1 Space between the two mirrors and meets the Ampoule head.

In deviation from this explanation, mirrors 134u-1 and 134u-2 alternatively or additionally also serve on the ampoule spit diverting passing laser radiation towards the ampoule skewer, so that an irradiation situation corresponding to FIG. 14 is achieved. On rotation of the ampoule (arrow 20u) can then be dispensed with.

FIG. 20 illustrates the integration of a mirror 170t (FIG. 18) in the substantially corresponding mirror 170v in a skewer device with two-piece skewer pliers 46v. As in the case of FIG. 18 the laser radiation 36v becomes parallel to the longitudinal axis of the ampoule 18v fed and through mirror surfaces towards the surface of the Ampoule skewer redirected.

The spit trigger pliers 46v have spit trigger members 186v, which are therefor are determined, when pulling the skewer at the top, expanding outwards Attack section of the ampoule skewer. Depending on the performance of the Laser radiation can be used to pull these skewer members 186v Provide stationary on the spit trigger pliers 46v so that the spit trigger members 186v can be irradiated with laser radiation. However, it is preferred that Skewer trigger members 186v movable in the skewer pliers 46v store so that they are only in the area of influence of the laser radiation be pushed in or swung in when the spit is pulled off shall be. This is shown by dashed arrows 188v in FIG. 20 indicated.

Figure 21 illustrates various ones in Figures 21a, 21b, 21c and 21d Possibilities such as the intensity distribution for preheating or / and can be selected for melting an ampoule 18w. 21a shows a circular laser focal spot 190w on the ampoule skewer, Fig. 21b shows an elongated focal spot 192w, the longitudinal axis of which is parallel to Ampoule longitudinal axis, Fig. 21c also shows an elongated focal spot 194w, the longitudinal axis of which, in contrast to the example in FIG. 21b is orthogonal to the longitudinal axis of the ampoule, and FIG. 21d shows two circular ones Focal spots 196w and 198w facing each other in the longitudinal direction of the ampoule are offset.

The intensity distribution of the laser radiation during preheating or during Melting is an important influencing factor, depending on the ampoule format (Ampoule geometry, wall thickness, wall material, etc.) for an optimal one Closing result is to be optimized. It is best to be empirical here proceed and for the different ampoule formats to be treated Make attempts. Such attempts are within the ability of the person skilled in the art and you will find parameters with which the respective ampoules are reliably closed. A certain one The following results are indicative for 2 ml and 20 ml ampoule formats:

Fusion of 2 ml ampoule formats

Without laser-assisted ampoule preheating, 40 ampoules / min could 280 W laser power can be realized with a good head shape. The laser exposure time for the individual ampoule was on the order of 850 msec. If you reduce the laser power, there are longer exposure times to laser radiation required. So at 144 W (without laser-assisted Ampoule preheating) for an exposure time of 2.3 sec Ampoules can be made with good strength and geometry.

A shortening of the laser exposure time per processing cycle is through Provision of laser-assisted ampoule preheating possible. So could with a laser power of 140 W for preheating and one Laser power of 144 W for melting 50 ampoules / min with good Head shape and firmness are closed, the laser exposure time each was in the order of 750 msec.

Fusion of 20 ml ampoule formats

Without laser-assisted ampoule preheating, a laser exposure time could of 2.3 sec and a laser power of 217 W ampoules be reliably closed. By introducing a laser-based Ampoule preheating could ampoules forming a good one Head shape and good strength are closed, being for a Laser power of 192 W for preheating and 203 W for that Melting 25 ampoules / min could be closed. The The duration of exposure to the laser radiation was in each case about 2.1 seconds.

These process parameters are only exemplary and must be adjusted according to the ampoules used. The However, parameters give orders of magnitude of laser powers and exposure times as starting points for empirical optimization can serve.

Fig. 22 shows a marking or / and labeling arrangement, which for Marking and / or labeling ampoules, especially already sealed ampoules 18x serves. The device is preferably in one Ampoule filling and closing device integrated according to the invention. The Device works with laser radiation 190x from a laser, for example one of the lasers of an ampule filling and -closing device, which itself for preheating and / or melting of ampoules. It is assumed that in the case of FIG. 22 device shown the laser radiation 190x from the laser beam 30x is branched off by means of a beam splitter arrangement 192x which leads to Preheating and / or melting ampoules is used. The laser radiation 190x is over a beam guiding and beam shaping arrangement 194x (symbolized by a lens) on a swivel mirror arrangement 196x with a first swivel mirror 198x and a second Swivel mirror 200x given, the swivel axes of the two Swivel mirrors are orthogonal to each other so that the beam and beam shaping arrangement 194x present laser beam 202x in mutually orthogonal directions can be pivoted so that any pattern and markings on a surface, especially the Surface of an ampoule, can be written to pattern, Write markings or inscriptions on the ampoule. The means the 196x swivel mirror arrangement (these can also be other optical Components, such as a plan field lens) controllable laser beam 204x calls a permanent change in the surface the ampoule emerges as it is written across the surface becomes. The ampoule wall material is combined in one by the laser beam Melted near the surface of the ampoule wall and if necessary even evaporated so that after labeling a permanent, practical Inscription or marking that cannot be removed remains.

23 shows a variant for a cyclical conveying and closing operation an ampoule filling and closing device according to the invention illustrated. The top part diagram shows the laser power used during preheating (curve section 220y) and during Melting (curve section 222y), whereby for the curve section 222y an alternative is shown in dashed lines, according to which the for Melting used laser power greater than that for preheating laser power used.

The second uppermost partial diagram symbolizes the rise in temperature of the ampoule area irradiated with laser radiation during the Preheating and during melting, being for a simplified Representation of a linear temperature rise was assumed. This but is not mandatory.

The third partial diagram from above shows the speed of the ampoule delivery for example by means of a conveyor rotor. In the shown In the clocked embodiment, the ampoules are irradiated with Laser radiation during time intervals in which the ampoules stand still, of a possibly provided rotation of the ampoules about their own axis for the ampoule is not evenly heated here.

The last partial diagram symbolizes the removal of an ampoule skewer, if skewer removal is provided at all. Represented symbolically is the skewer pulling force required for skewer pulling. The skewer stripping takes place at the end of the melting interval.

The diagram in FIG. 24 shows a variant of the cyclical filling and Closing operation of an ampoule filling and closing device according to the invention. In this mode of operation, preheating and melting follow directly on top of each other and may not be clearly different from each other distinguishable (curve section 224z). A clear distinction from Preheating and melting is possible if for that Preheating and melting different laser power is used. Such a situation is indicated by a dashed line Curve section 222z, which represents the melting, whereby for the Melt about twice the laser power than for preheating is used. The resulting temperature of using laser radiation irradiated ampoule sections is in the second top part diagram represented symbolically, again for a simplified representation of a linear increase in temperature during preheating and was assumed during the melting.

The third top diagram shows that the preheating during the transport of the ampoule, while melting at stationary ampoule (apart from any ampoule rotation) takes place. If provided, the skewer is also removed (bottom Partial diagram) with the ampoule stopped.

25 illustrates the continuous conveying and capping operations with an appropriately trained ampoule filling and closing device according to the invention. Here the ampoule moves continuously proceeding at a constant speed, as evidenced by the third uppermost Partial diagram results. The first, the second and the fourth partial diagram from above correspond to the first, second and fourth partial diagram of the Fig. 24, so that reference can be made to the comments on this. The Curve sections in the first partial diagram have been given the reference symbols 222za and 222za marked.

The following are exemplary embodiments of an inventive Device for machining a workpiece by means of electromagnetic Radiation described, being in the drawings for the same or for themselves corresponding components have the same reference numerals each without a small one Letters are used. To the for the embodiments of Fig. 1 - 25 reference numerals used are not used.

26 is a first embodiment of an inventive one Device 2 shown, the means for generating electromagnetic Has radiation, in this embodiment by a laser 4 are formed. When operating the device 2 for processing a In this embodiment, the cylindrical workpiece 6 is generated by the laser 4 laser light which forms through a mirror 8, the beam guiding means the electromagnetic radiation, in this embodiment the Laser radiation of the laser 4 from at least two directions Straighten the workpiece 6 to be machined.

In this exemplary embodiment, the mirror 8 has a base body 10 with a cylindrical outer surface, on the inner surface of a Reflection surface 12 is formed, which is to be processed Workpiece 6 narrowed in a funnel shape and which the incident laser light of the laser 4 reflected on the workpiece 6. In this embodiment is the reflection surface 12 of the mirror 8 to an axis of rotational symmetry, symbolized by a dash-dotted line 14 in FIG. 26 is rotationally symmetrical, such that the reflection surface 12 of the mirror 8 narrows conically towards the workpiece 6.

Furthermore, the mirror 8 has an insertion opening 16 for inserting the Workpiece 6 in the effective range of the reflected laser light. The insertion opening 16 is in this embodiment to the rotational symmetry axis 14 of the reflection surface 12 coaxially. Your clear width can essentially the extent of the workpiece 6 in a direction of insertion correspond to the vertical plane, such that the workpiece 6 in Machining position is closely received in the insertion opening 16. The light one However, the width of the insertion opening 16 can also be such that the Workpiece 6 with a radial distance from the walls of the insertion opening 16 is included, as shown in Fig. 26.

The device 2 according to FIG. 26 also has a positioning device 18 on, in this embodiment by a feed device for the linear feed of the workpiece 6 in its axial direction, ie in a direction symbolized by a double arrow 20 in FIG. 26, is trained. The workpiece 6 is in a holder 22 of the positioning device 18 added. It is also possible to relative the mirror 8 to move the workpiece 6.

27 that the reflection surface 12 of the mirror 8 is rotationally symmetrical.

When performing the method according to the invention by means of The inventive device 2, the laser 4 generates laser light, the parallel rays on the reflection surface 12 of the rotationally symmetrical Mirror 8 form a beam spot, the projection of which in one Rotation symmetry axis of the reflection surface 12 vertical plane in the essentially concentric to the rotational symmetry axis 14 and in is essentially annular. The reflection surface 12 reflects that incident laser light on the workpiece 6, which is in the in Fig. 26th shown processing position in the effective range of the reflected Laser light is located.

In the arrangement shown in Fig. 26, the reflected laser light strikes along a closed, over the entire circumference of the Workpiece 6 extending annular area on the workpiece 6th on, so that in this area of action of the laser light essentially homogeneous intensity distribution and thus a uniform one Action of the laser light on the surface of the to be processed Workpiece 6 is achieved.

Should, for example, material from the surface by the laser radiation are removed in the arrangement shown in FIG. 26 in that extending over the entire circumference of the workpiece 6 Area of action a homogeneous material removal without the workpiece 6 rotated around its axis of symmetry during machining must become.

If additionally a homogeneous in the axial direction of the workpiece 6 If material removal is desired, the workpiece 6 can, for example through the positioning device 18 of the arrow 20 over its entire Axial expansion through the effective range of the reflected laser light be moved.

Since complex positioning devices are not required, the Device 2 according to the invention simple and robust in construction; complex Adjustment work is not necessary.

Since the workpiece 6 is machined simultaneously over its entire circumference considerable time is saved.

The geometry of the reflection surface 12 of the mirror 8 is within wide limits selectable. By appropriate choice of the geometry of the reflection surface 12 of the mirror 8 can be any intensity distributions on the workpiece 6 achieve.

Basically, it is sufficient if the laser light from the laser 4 is direct is directed onto the reflection surface 12. However, it can be in the path of propagation the laser light beam shaping means can be arranged, such as This is shown in Fig. 28, which is a second embodiment of the device 2 according to the invention, wherein in FIG. 28 the laser 4 and the positioning device 18 are not shown.

28 differs from that 26 in that two refractive optics, namely one arranged behind the laser in the direction of incidence of the laser light Converging lens 24 and an incidence behind the converging lens 24 arranged axicon 26 are provided, the beam shaping means form. The converging lens 24 and the axicon 26 form the incident one Laser radiation such that on the reflection surface 12 of the mirror 8 a Beam spot is formed, its projection in an axis of rotation symmetry 14 of the reflecting surface 12 vertical plane essentially concentric to the rotational symmetry axis 14 and annular with is less radial expansion. In this way, the reflected hits Laser light along a closed, over the entire circumference of the Workpiece 6 extending narrow area on the surface of the Workpiece 6 so that, for example, by removing material narrow circumferential groove can be formed on the workpiece 6.

The embodiment according to FIG. 28 is, for example, also suitable for Seal glass ampoules by fusing the ampoule neck. For this purpose, an ampoule with its ampoule neck in the axial direction of the Ampoule narrow range of action of the reflected laser radiation brought so that the ampoule neck under the effect of laser radiation is melted, what to seal in the desired manner Closing the ampoule leads. The embodiments according to the Figures 26-28 and the embodiment to be described below 29 can be used to close glass ampoules; the embodiment of FIG. 3 appears due to the concentration of Laser radiation on a relatively narrow area for this purpose though particularly useful.

29 is a third embodiment of the invention Device 2 shown, which differs from the embodiment shown in FIG. 26 differs in that the mirror 8 at its in the direction of incidence the front side of the laser light is transparent to the laser light Cover 28 has. The cover 28 and the reflective surface 12 of the Mirror 8 form walls of a processing chamber 30 in which the Workpiece 6 is recorded in the machining position shown in FIG. 29 is. The processing chamber 5 has one in the base body 10 of the Mirror 8 formed inlet opening 32 for protective and / or process gas.

During operation of the device shown in FIG. 29, protective gas or Process gas through the inlet opening 32 into the processing chamber 30 and flows out through the insertion opening 16 again. However, it is also possible to seal the processing chamber 30 from the environment. In the processing chamber 30, the workpiece 6 is in the above described way edited. A particular advantage of the embodiment 29 is that, for example, when editing of the workpiece 6 under a protective gas atmosphere only the small volume the processing chamber 30 must be kept under protective gas. In in a corresponding manner, a sealable processing chamber 30 Machining of the workpiece 6 in a vacuum, then only the small volume of the processing chamber 30 to be evacuated needs.

30 shows a second exemplary embodiment of the invention Mirror 8 shown, in which the reflection surface 12 is rotationally symmetrical is formed, however, in contrast to the reflective surface of the embodiment according to FIGS. 26 to 29 not conical, but narrowed in a substantially parabolic cross-section.

In summary, the invention relates to an ampoule filling and closing device and an ampoule sealing process. It is suggested, to close the ampoules under the influence of laser radiation, for what in the case of the ampule filling and closing device according to the invention at least one laser is assigned to a locking station of the device.

Claims (11)

Ampule filling and closing device (10) comprising: a filling station (24) for filling ampoules (18), a closing station (26) for closing ampoules by fusing an ampoule filling opening, the closing station being assigned at least one laser (28) for melting the ampoule filling opening under the action of laser radiation, a conveying device (12) with an ampoule conveying section for feeding empty ampoules to the filling station and filled ampoules from the filling station to the closing station and for discharging filled ampoules from the closing station, characterized, that an opening station (54a, 56a) is provided which opens the ampoules fed to the ampoule filling and closing device in the closed state before being fed to the filling station, and that the opening station is assigned at least one laser (50a) for opening the ampoules under the action of laser radiation. Device according to claim 7, characterized in that the opening station (54a, 56a, 50a) is designed for the respective ampoule (58a) in at least three stages with a preheating stage for releasing a negative pressure in the closed ampoule, an overpressure relief stage for releasing an excess pressure in the ampoule by creating a compensating opening in the ampoule by laser radiation and an opening step for producing the ampoule filling opening by laser radiation, optionally with the additional use of a mechanical tool for opening enlargement and / or removing molten ampoule wall material. Device according to Claim 1 or 2, characterized in that the device has a shielding chamber (70) in which the filling station, the closing station and the opening station are arranged, the at least one laser (28b; 28d) preferably being arranged outside the shielding chamber and the laser radiation can be fed into the shielding chamber through a window arrangement (78b; 78d) which is transparent to the laser radiation. Device according to claim 3, characterized in that the shielding chamber (70) is a clean room chamber and / or air laminar flow chamber. Device according to one of claims 1-4, characterized in that it is in any case arranged with its filling station, its closing station and possibly its opening station in a room of higher air quality, in particular clean room, whereas the laser is preferably arranged in an adjacent room of lower air quality. Method for opening a closed ampoule by melting an ampoule filler opening in preparation for filling filler into the ampoule through the ampoule filler opening, characterized in that the ampoule filler opening is melted under the action of laser radiation, optionally with the additional use of a mechanical tool for widening the opening and / or removing molten ampoule wall material. A method according to claim 6, characterized in that the opening of the ampoule takes place in at least three stages, with a preheating stage for reducing a negative pressure in the closed ampoule, an overpressure relief stage for reducing an excess pressure in the ampoule by creating a compensation opening in the ampoule and an opening stage to create the ampoule fill opening. A method according to claim 6 or 7, characterized in that the closing or / and opening takes place under clean room conditions and / or air-laminar flow conditions. Ampule filling and closing device (10) comprising: a filling station (24) for filling ampoules (18), a closing station (26) for closing ampoules by fusing an ampoule filling opening, the closing station being assigned at least one laser (28) for melting the ampoule filling opening under the action of laser radiation, a conveying device (12) with an ampoule conveying section for feeding empty ampoules to the filling station and filled ampoules from the filling station to the closing station and for discharging filled ampoules from the closing station, characterized, that the at least one laser (28e) assigned beam guiding means (90e) are suitable for tracking the laser radiation in accordance with a movement of the ampoules through the conveying device (12e) in order to preheat each ampoule to be sealed by irradiation with laser radiation or / and at least partially closing it with the ampoule moving along the ampoule conveying path. Ampule filling and closing device (10) comprising: a filling station (24) for filling ampoules (18), a closing station (26) for closing ampoules by fusing an ampoule filling opening, the closing station being assigned at least one laser (28) for melting the ampoule filling opening under the action of laser radiation, a conveying device (12) with an ampoule conveying section for feeding empty ampoules to the filling station and filled ampoules from the filling station to the closing station and for discharging filled ampoules from the closing station, characterized in that a laser beam guiding arrangement (90e; 110f; 112g; 112h; 130m; 142r) is assigned to the at least one laser in order to track the laser radiation according to a conveying movement of the respective ampoule along the conveying path, or / and track the laser radiation when the respective ampoule skewer is pulled in the skewer pulling direction or deflect it in such a way that the detachment of the skewer from the other ampoule, in particular an interruption of a material thread which may arise during the pulling off, is promoted, or / and to forward the laser radiation to a subsequent ampoule after the respective ampoule has been closed, in particular after the ampoule spike has been removed, and / or after the ampoule has been opened. Method for closing an ampoule (18) by melting an ampoule opening, in which the ampoule opening is sealed under the action of laser radiation,
characterized in that the laser radiation is supplied to the ampoule via a laser beam guiding or / and laser beam shaping arrangement in order to to provide a predetermined intensity distribution of the laser radiation acting on the ampoule during preheating and / or during closing or / and during opening, or / and to track the laser radiation in accordance with a conveying movement of the ampoule along a / the conveying path, or / and track or deflect the laser radiation when the ampoule skewer is pulled off in the skewer pulling direction in such a way that the detachment of the skewer from the remaining ampoule, in particular an interruption of a material thread which may arise during the pulling off, is promoted, or / and to forward the laser radiation to a subsequent ampoule after the ampoule has been closed, in particular after the ampoule spike has been pulled off, and / or after the ampoule has been opened.

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