EP1179020A4 - Low-dose il-1beta-induced photoreceptor cell rescue without retinal dysplasia - Google Patents

Low-dose il-1beta-induced photoreceptor cell rescue without retinal dysplasia

Info

Publication number
EP1179020A4
EP1179020A4 EP00932180A EP00932180A EP1179020A4 EP 1179020 A4 EP1179020 A4 EP 1179020A4 EP 00932180 A EP00932180 A EP 00932180A EP 00932180 A EP00932180 A EP 00932180A EP 1179020 A4 EP1179020 A4 EP 1179020A4
Authority
EP
European Patent Office
Prior art keywords
1beta
dose
low
photoreceptor cell
retinal dysplasia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00932180A
Other languages
German (de)
French (fr)
Other versions
EP1179020A1 (en
Inventor
Henry Klassen
Simon J Whiteley
Michael J Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schepens Eye Research Institute Inc
Original Assignee
Schepens Eye Research Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schepens Eye Research Institute Inc filed Critical Schepens Eye Research Institute Inc
Publication of EP1179020A1 publication Critical patent/EP1179020A1/en
Publication of EP1179020A4 publication Critical patent/EP1179020A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP00932180A 1999-05-06 2000-05-08 Low-dose il-1beta-induced photoreceptor cell rescue without retinal dysplasia Withdrawn EP1179020A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13285599P 1999-05-06 1999-05-06
US132855P 1999-05-06
PCT/US2000/012565 WO2000068267A1 (en) 1999-05-06 2000-05-08 LOW-DOSE IL-1β-INDUCED PHOTORECEPTOR CELL RESCUE WITHOUT RETINAL DYSPLASIA

Publications (2)

Publication Number Publication Date
EP1179020A1 EP1179020A1 (en) 2002-02-13
EP1179020A4 true EP1179020A4 (en) 2004-08-18

Family

ID=22455907

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00932180A Withdrawn EP1179020A4 (en) 1999-05-06 2000-05-08 Low-dose il-1beta-induced photoreceptor cell rescue without retinal dysplasia

Country Status (5)

Country Link
EP (1) EP1179020A4 (en)
JP (1) JP2003525206A (en)
AU (1) AU4994000A (en)
CA (1) CA2372738A1 (en)
WO (1) WO2000068267A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015608A1 (en) * 1992-02-14 1993-08-19 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5667968A (en) * 1989-08-30 1997-09-16 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015608A1 (en) * 1992-02-14 1993-08-19 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KLASSEN, H. J. [REPRINT AUTHOR] ET AL: "Photoreceptor rescue in the RCS rat following intravitreal IL 1beta injections without concomitant retinal dysplasia.", IOVS, (MARCH 15, 1999) VOL. 40, NO. 4, PP. S222. PRINT. MEETING INFO.: ANNUAL MEETING OF THE ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY. FORT LAUDERDALE, FLORIDA, USA. MAY 9-14, 1999. ASSOCIATION FOR RESEARCH IN VISION AND OPTHALMOLOGY., May 1999 (1999-05-01), XP008031440 *
See also references of WO0068267A1 *

Also Published As

Publication number Publication date
AU4994000A (en) 2000-11-21
EP1179020A1 (en) 2002-02-13
WO2000068267A9 (en) 2001-06-14
CA2372738A1 (en) 2000-11-16
WO2000068267A1 (en) 2000-11-16
JP2003525206A (en) 2003-08-26

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20011205

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