EP1161147A4 - Peptide mimics useful for treating disease - Google Patents

Peptide mimics useful for treating disease

Info

Publication number
EP1161147A4
EP1161147A4 EP98964947A EP98964947A EP1161147A4 EP 1161147 A4 EP1161147 A4 EP 1161147A4 EP 98964947 A EP98964947 A EP 98964947A EP 98964947 A EP98964947 A EP 98964947A EP 1161147 A4 EP1161147 A4 EP 1161147A4
Authority
EP
European Patent Office
Prior art keywords
treating disease
peptide mimics
mimics useful
useful
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98964947A
Other languages
German (de)
French (fr)
Other versions
EP1161147A1 (en
Inventor
Soldano Ferrone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Medical College
Original Assignee
New York Medical College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Medical College filed Critical New York Medical College
Publication of EP1161147A1 publication Critical patent/EP1161147A1/en
Publication of EP1161147A4 publication Critical patent/EP1161147A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001169Tumor associated carbohydrates
    • A61K39/001171Gangliosides, e.g. GM2, GD2 or GD3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
EP98964947A 1998-12-24 1998-12-24 Peptide mimics useful for treating disease Withdrawn EP1161147A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/027633 WO2000038515A1 (en) 1998-12-24 1998-12-24 Peptide mimics useful for treating disease

Publications (2)

Publication Number Publication Date
EP1161147A1 EP1161147A1 (en) 2001-12-12
EP1161147A4 true EP1161147A4 (en) 2002-07-24

Family

ID=22268554

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98964947A Withdrawn EP1161147A4 (en) 1998-12-24 1998-12-24 Peptide mimics useful for treating disease

Country Status (5)

Country Link
EP (1) EP1161147A4 (en)
JP (1) JP2002533357A (en)
AU (1) AU2016199A (en)
CA (1) CA2334958A1 (en)
WO (1) WO2000038515A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001026672A1 (en) * 1999-10-13 2001-04-19 Roswell Park Memorial Institute Induction of a strong immune response to a self-tumor associated antigen
EP1287831B1 (en) * 2001-09-03 2006-11-22 Bio Life Science Forschungs- und Entwicklungsges.m.b.H. Antigen mimotopes and vaccine against cancerous diseases
AU2003213700A1 (en) * 2002-03-01 2003-09-16 Applied Immune Technologies Immunogens for treatment of neoplastic and infectious disease
US6998237B1 (en) * 2002-07-11 2006-02-14 Health Research, Inc. GD3 peptide mimics
JP5836125B2 (en) * 2008-10-16 2015-12-24 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション Fully human antibodies against high molecular weight melanoma-related antigens and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011296A1 (en) * 1988-05-17 1989-11-30 Raychaudhuri, Syamal Anti-idiotype antibodies to anti-human high molecular weight-melanoma associated antigen
EP0668350A1 (en) * 1994-02-16 1995-08-23 Akzo Nobel N.V. Melanoma associated antigenic polypeptide, epitopes thereof and vaccines against melanoma
WO1997034613A1 (en) * 1996-03-19 1997-09-25 University Of Virginia Patent Foundation Peptides recognized by melanoma-specific a1-, a2- and a3-restricted cytotoxic lymphocytes, and uses therefor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5662907A (en) * 1992-08-07 1997-09-02 Cytel Corporation Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011296A1 (en) * 1988-05-17 1989-11-30 Raychaudhuri, Syamal Anti-idiotype antibodies to anti-human high molecular weight-melanoma associated antigen
EP0668350A1 (en) * 1994-02-16 1995-08-23 Akzo Nobel N.V. Melanoma associated antigenic polypeptide, epitopes thereof and vaccines against melanoma
WO1997034613A1 (en) * 1996-03-19 1997-09-25 University Of Virginia Patent Foundation Peptides recognized by melanoma-specific a1-, a2- and a3-restricted cytotoxic lymphocytes, and uses therefor

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BAKKER A B H ET AL: "ANALOGUES OF CTL EPITOPES WITH IMPROVED MHC CLASS-I BINDING CAPACITY ELICIT ANTI-MELANOMA CTL RECOGNIZING THE WILD-TYPE EPITOPE", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 70, no. 3, 1997, pages 302 - 309, XP000917224, ISSN: 0020-7136 *
CORTESE R ET AL: "Identification of biologically active peptides using libraries displayed on phage", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 6, no. 1, 1995, pages 73 - 80, XP002107140, ISSN: 0958-1669 *
DYALL R ET AL: "HETEROCLITIC IMMUNIZATION INDUCES TUMOR IMMUNITY", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 188, no. 9, 2 November 1998 (1998-11-02), pages 1553 - 1561, XP002947142, ISSN: 0022-1007 *
HOESS R ET AL: "IDENTIFICATION OF A PEPTIDE WHICH BINDS TO THE CARBOHYDRATE-SPECIFIC MONOCLONAL ANTIBODY B3", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 1, no. 128, 15 June 1993 (1993-06-15), pages 43 - 49, XP001071246, ISSN: 0378-1119 *
MITTELMAN A ET AL: "HUMAN HIGH MOLECULAR WEIGHT MELANOMA-ASSOCIATED ANTIGEN (HMW-MAA) MIMICRY BY MOUSE ANTI-IDIOTYPIC MONOCLONAL ANTIBODY MK2-23: INDUCTION OF HUMORAL ANTI-HMW-MAA IMMUNITY AND PROLONGATION OF SURVIVAL IN PATIENTS WITH STAGE IV MELANOMA", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 89, 1992, pages 466 - 470, XP000887127, ISSN: 0027-8424 *
PARKHURST ET AL: "Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 157, 1996, pages 2539 - 2548, XP002096010, ISSN: 0022-1767 *
PARMIANI G: "Future perspectives in specific immunotherapy of melanoma", EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, vol. 34, April 1998 (1998-04-01), pages 42 - 47, XP004284900, ISSN: 0959-8049 *
ROSENBERG S A ET AL: "Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma", NATURE MEDICINE, NATURE PUBLISHING, CO, US, vol. 4, no. 3, 1 March 1998 (1998-03-01), pages 321 - 327, XP002091661, ISSN: 1078-8956 *
See also references of WO0038515A1 *

Also Published As

Publication number Publication date
AU2016199A (en) 2000-07-31
WO2000038515A1 (en) 2000-07-06
CA2334958A1 (en) 2000-07-06
JP2002533357A (en) 2002-10-08
EP1161147A1 (en) 2001-12-12

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