EP1148904B9 - Ensemble de securite pour une seringue pre-remplie d'injection de liquide, notamment d'un medicament - Google Patents

Ensemble de securite pour une seringue pre-remplie d'injection de liquide, notamment d'un medicament Download PDF

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Publication number
EP1148904B9
EP1148904B9 EP99923709A EP99923709A EP1148904B9 EP 1148904 B9 EP1148904 B9 EP 1148904B9 EP 99923709 A EP99923709 A EP 99923709A EP 99923709 A EP99923709 A EP 99923709A EP 1148904 B9 EP1148904 B9 EP 1148904B9
Authority
EP
European Patent Office
Prior art keywords
sheath
cap
syringe
assembly according
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP99923709A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1148904B1 (fr
EP1148904A1 (fr
Inventor
Roger Denis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Plastic Omnium SE
Original Assignee
Plastic Omnium SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9533842&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1148904(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plastic Omnium SE filed Critical Plastic Omnium SE
Priority to EP07120297A priority Critical patent/EP1892004A3/fr
Priority to EP03290416A priority patent/EP1329234B1/fr
Publication of EP1148904A1 publication Critical patent/EP1148904A1/fr
Application granted granted Critical
Publication of EP1148904B1 publication Critical patent/EP1148904B1/fr
Publication of EP1148904B9 publication Critical patent/EP1148904B9/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3261—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user triggered by radial deflection of the anchoring parts between sleeve and syringe barrel, e.g. spreading of sleeve retaining hooks having slanted surfaces by engagement with conically shaped collet of the piston rod during the last portion of the injection stroke of the plunger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3261—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user triggered by radial deflection of the anchoring parts between sleeve and syringe barrel, e.g. spreading of sleeve retaining hooks having slanted surfaces by engagement with conically shaped collet of the piston rod during the last portion of the injection stroke of the plunger
    • A61M2005/3264—Trigger provided at the proximal end, i.e. syringe end opposite to needle mounting end

Definitions

  • the present invention relates to a set of safety for a pre-filled syringe injection liquid, including a drug.
  • a safety assembly for an injection syringe pre-filled liquid comprising a tubular body, forming a tank for the liquid, carrying a needle liquid injection, and a pusher mounted movable in the body between waiting and ending positions injection.
  • the pusher of the syringe comprises a maneuvering end external to the body of the syringe and an inner end to the body of this bearing syringe A piston.
  • the operating end of the pusher is still called pusher head.
  • Some medical products such as vaccines, heparins and their derivatives and other medicinal products accurate, can not be stored in containers or plastic syringes as a result of recovery rate moisture that may compromise the composition.
  • the problem is therefore to adapt a mechanism of safety on preferably glass syringes, especially from 0.1 to 2 ml capacity, any type of internal mechanism to these syringes being excluded.
  • the sterility requirement forbids any internal manipulation of the syringe after filling.
  • US-A-5562 626 discloses a set of security of the type defined in the preamble of claim 1.
  • the object of the invention is to overcome the disadvantages above, while meeting the following criteria: low bulk, adaptation at the end of the chain before packaging, single-trigger, automatic safety, with independent control of the human will, protection closer to the 100% desired.
  • the subject of the invention is a set of security, of the type described in US-A-5,562,626, comprising the features defined in the characterizing part of claim 1.
  • the subject of the invention is also a device including the characteristics defined in claim 13.
  • FIGS. 1 to 3 show a set of safety for a classic injection syringe s liquid, in particular a medical liquid, according to a first embodiment embodiment of the invention.
  • This set of security is designated by the general reference E.
  • the syringe S is pre-filled, ready for use, and comprises a tubular body K, forming a reservoir for the liquid, carrying a needle A for injecting the liquid, and a pusher mounted movable in the body K between a waiting position, as shown in FIG. and an end position of liquid injection, such as shown in Figure 2.
  • the pusher P has a first end PE, external to the body K, and a second end PI, internal to body K, carrying a conventional piston PO.
  • the outer end PE forms a maneuvering end of the pusher.
  • the set E comprises a safety sleeve tube in which the syringe is housed, in particular the K.
  • the sheath of revolution, consists of for example, by a cylindrical tube 1 made of plastic or in any other material with sufficient transparency to allow visualization of the liquid contained in the body K of the syringe as well as a possible label identification of the drug. It will be noted that the tube cylindrical 1 is stepped.
  • the body K is axially displaceable in the tube 1 between an active position in which the needle A makes protruding through a distal (upper) end of the tube 1, and a protective position in which the needle A is retracted into tube 1.
  • the active position is shown in Figures 1 and 2.
  • the position of protection is shown in Figure 3.
  • the body K of the syringe comprises a distal end bearing needle A and one end proximal provided with a collar CL.
  • the inner surface of the tube 1 has three guides 2 in relief arranged in the longitudinal direction of this tube 1, spaced 120 ° apart, intended to center the body K of the syringe, reduce the play and improve the sliding of the body K in the tube 1, while allowing the passage of a classic rubber cape C (shown in phantom in Figure 1) protecting the needle A before use of the syringe.
  • the proximal end of the tube 1 carries, from bottom to high, a first inner housing of revolution 3 extended by a second internal housing of revolution 4 of diameter higher than the first internal housing.
  • the body K is immobilized with respect to the tube 1 to using blocking means comprising, on the one hand, a seat 4E of support of the flange CL formed by a shoulder internal delimiting the second housing 4, and secondly, retractable means for clamping the collar CL against this seat 4E, carried by the proximal end of the tube 1.
  • blocking means comprising, on the one hand, a seat 4E of support of the flange CL formed by a shoulder internal delimiting the second housing 4, and secondly, retractable means for clamping the collar CL against this seat 4E, carried by the proximal end of the tube 1.
  • the retractable clamping means are formed by two legs 5, substantially diametrically opposed, partially cut in the wall of the tube 1 delimiting the second housing 4.
  • the legs 5 are terminated by lugs retractable 6 intended to maintain the collar CL of the body of the syringe resting against the seat 4E.
  • the legs 5 are folded so as to extend substantially in a diametral longitudinal plane of the tube.
  • the retractable clamping means could have only one leg 5.
  • the body K of the syringe is resiliently biased towards its protective position by a pushing spring R disposed in the first housing 3.
  • This spring R is in support, on the one hand, on an internal shoulder 3E, delimiting the first internal housing 3, and on the other hand, on the collar CL of the body K of the syringe.
  • the shoulder internal support 3E is arranged between the support seat 4E of the flange CL and the distal end of the tube 1.
  • the lugs 6 thus make it possible to immobilize the body K with respect to the tube 1 in the active position by opposing the elastic spring force of spring R.
  • proximal end of the second inner housing 4 is bounded by an inner ring 7 come from molding with the tube 1.
  • the means for blocking the body K of the syringe by relative to tube 1 are releasable using activated means when the pusher P is in the end of injection position.
  • the means for releasing the blocking means comprise a cap of revolution 8, preferably made of plastic, sliding axially in the second housing 4 of the tube 1, between a high standby position, as shown in FIG. 1, and a position retraction of the lugs 6, as shown in FIG. Figure 2.
  • the cap 8 is crossed by the pusher P which extends through a hole 9 formed in the end proximal of this cap 8.
  • the cap 8 also has lugs interiors 10 spaced from each other by 90 °, and a ring outside 11 come molding with the distal end of this cap.
  • the inner ring 7 of the second housing 4 and the outer ring 11 of the cap 8 delimit complementary annular shoulders, forming abutments, limiting the stroke of this cap 8, after release of means for blocking the body K, by opposing the force resilient return spring R (see Figure 3).
  • the complementary rings 7, 11 therefore act as limiter back of the hood 8.
  • the tube 1 and the cap 8 comprise means additional measures of immobilization in rotation of one report to the other.
  • These complementary means of immobilization in rotation include, for example, less a longitudinal groove 13 formed in the cap 8, cooperating by interlocking with a corresponding finger 13A radially extending the inner ring 7 of the second 4.
  • the cap has two diametrically opposite grooves 13 as illustrated in Figures 1 to 3.
  • the introduction of the syringe in the set of security E can be carried out as follows.
  • the body K of the syringe is filled of liquid to be injected. This liquid is retained in the body K by the piston PO. Pusher P is separated from this piston.
  • the body K of the pre-filled syringe is placed in the tube 1 by snapping the flange CL under the lugs 6 after having compressed the spring R into the first housing 3.
  • cap 8 is engaged in the second housing 4 being for example depressed in this second housing 4 until the outer ring 11 arrives at contact pins 6, as shown on the figure 1.
  • the pusher P of the syringe is connected to the PO piston by introducing the distal end of this pusher in the cap 8 and the tube 1, through the orifice 9 of this cap 8.
  • the safety assembly E is then ready for use in the configuration illustrated in Figure 1, the needle A syringe protruding through the end distal of the tube 1.
  • the grip at the tube 1 is carried out at using external gripping means carried by the tube 1, intended to be grasped by the fingers of a user to inject the liquid by axial approximation of the outer end PE of the pusher and means of gripping.
  • the gripping means of the tube 1 comprise a shoulder 1E arranged on the outer surface of the tube 1.
  • the user To carry out the injection of the liquid, the user enter the set E between the index and the middle finger. Thumb exerts a pressure of the syringe on the outer end PE of pusher. The index and the middle finger hold the tube 1 in grasping the grasping shoulder 1E.
  • the user pushes the PE pusher into the body of the syringe by axially bringing the PE end of the push of the grip shoulder 1E, this up reach the end of injection position shown on the figure 2.
  • the spring R relaxes and pushes the empty syringe upwards (considering the figures) in order to snap the flange CL of the body between the edge of the orifice E of the cap and lugs 10 as shown on the Figure 3.
  • the cap 8 also moves under the effect of the restoring force of the spring R towards the position shown in FIG. 3 in which the rings 7, 11 cooperate between them to limit the stroke of the cap 8 and therefore the retraction stroke of the syringe.
  • needle A is retracted into the tube 1 thus achieving a 100% safety.
  • FIGS. 4 to 9 a set safety device E according to a second embodiment of the invention.
  • This last embodiment makes it possible in particular the use of a syringe with a vaccine.
  • the elements are recognized similar to those of the previous embodiment, namely the tube 1 comprising the housing 3 in which is arranged the spring R.
  • the proximal end of the tube. 1 is extended by two lugs 33, 34, preferably diametrically opposed.
  • the number of pins 33, 34 may be less than or greater than two, pins 33, 34 constitute locking means having a function immobilization of the body K of the syringe relative to the tube by clamping the flange CL of this body between the pins 33, 34 and the support seat 4E.
  • the function of the pins 33, 34 is therefore similar to those of the lugs 6 of the first embodiment of the invention.
  • Two gripping wings 15 have come from molding with the proximal end of the tube 1 and arranged to 180 ° from each other.
  • the tube 1 is shown isolated from the assembly E in FIG. 11.
  • the cap 8 (see in particular Figures 8 and 9) comprises in this case two tabs longitudinally 38, 39, substantially diametrically opposed, extending its distal end.
  • the proximal end of the cap 8 is pierced with a hole 40.
  • the hood 8 comprises in addition two vertical longitudinal lights 41, 42 90 ° offset from tabs 38, 39.
  • the lights 41, 42 cooperate by interlocking with the fins 15 so as to form means additional immobilization in rotation of the cap 8 relative to the tube 1.
  • the lugs 33, 34 are retractable, so as to release the collar CL, by cooperation with ramps 43, 44 limiting the proximal ends of the lumens 41, 42.
  • the hole 40 of the cap allows the mounting of the pusher in the injection assembly.
  • the pusher P is subject to cap 8 using conventional means not shown.
  • Figure 4 shows the safety assembly E in a configuration ready for its use, the needle of the syringe protruding through the distal end of the tube 1.
  • the user performs an injection, in particular intra-muscular or subcutaneously, holding tube 1 between the index finger and the major, thanks to the fins 15, while pressing with the inch on the outer PE end of the pusher.
  • the cap 8 being subject to the pusher P, this cap sinks under the effect of thumb pressure in the same direction as the push P until reaching the position shown on the figure 5.
  • cap 8 spreads the lugs 33, 34 by cooperation of ramps 43, 44 of the cap 8 with lugs 33, 34, which effect of releasing the spring R.
  • latching means comprise locking studs 45, 46 formed on the free ends of the tongues 38, 39 cooperating by interlocking with holes 47, diametrically arranged on the proximal end of the tube 1 (see Figure 7).
  • the syringe and the needle are well self-retractable, the tube 1 constituting a stable part serving as a fixed support.
  • the tube 1 by its fins 33., 36 ensures stability on a non-planar surface.
  • the embodiments described above ensure the retraction of the needle perfectly in line by compared to its introduction while fulfilling a function anti-accident for caregivers.
  • the retraction of the needle is realized with one hand, without a special gesture, respecting the medical rules as well as the practices of the staff caregivers.
  • the invention makes it possible for caregivers as well as persons to handle, convey or destroy used syringes, to avoid any risk of accidents.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Environmental & Geological Engineering (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP99923709A 1998-12-08 1999-06-09 Ensemble de securite pour une seringue pre-remplie d'injection de liquide, notamment d'un medicament Expired - Lifetime EP1148904B9 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07120297A EP1892004A3 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament
EP03290416A EP1329234B1 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9815628 1998-12-08
FR9815628A FR2787335B1 (fr) 1998-12-08 1998-12-08 Securite pour seringues pre-remplies
PCT/FR1999/001369 WO2000033900A1 (fr) 1998-12-08 1999-06-09 Ensemble de securite pour une seringue pre-remplie d'injection de liquide, notamment d'un medicament

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP03290416A Division EP1329234B1 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament
EP03290416.1 Division-Into 2003-02-20

Publications (3)

Publication Number Publication Date
EP1148904A1 EP1148904A1 (fr) 2001-10-31
EP1148904B1 EP1148904B1 (fr) 2005-02-09
EP1148904B9 true EP1148904B9 (fr) 2005-10-26

Family

ID=9533842

Family Applications (3)

Application Number Title Priority Date Filing Date
EP03290416A Expired - Lifetime EP1329234B1 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament
EP07120297A Withdrawn EP1892004A3 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament
EP99923709A Expired - Lifetime EP1148904B9 (fr) 1998-12-08 1999-06-09 Ensemble de securite pour une seringue pre-remplie d'injection de liquide, notamment d'un medicament

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP03290416A Expired - Lifetime EP1329234B1 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament
EP07120297A Withdrawn EP1892004A3 (fr) 1998-12-08 1999-06-09 Ensemble de sécurité pour une seringue pré-remplie d'injection de liquide, notamment d'un médicament

Country Status (9)

Country Link
US (1) US6872190B1 (pt)
EP (3) EP1329234B1 (pt)
JP (1) JP4125491B2 (pt)
AT (2) ATE385818T1 (pt)
AU (1) AU4048199A (pt)
CA (1) CA2361100A1 (pt)
DE (2) DE69938157T2 (pt)
FR (1) FR2787335B1 (pt)
WO (1) WO2000033900A1 (pt)

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FR2801795B1 (fr) 1999-12-07 2002-07-05 Plastef Investissements Dispositif de support de securite pour une seringue et ensemble d'un tel dispositif et d'une seringue
US6613022B1 (en) 2000-05-05 2003-09-02 Safety Syringes, Inc. Passive needle guard for syringes
AUPR657501A0 (en) * 2001-07-26 2001-08-16 Afra Design Pty Limited Protective syringe
FR2830765B1 (fr) 2001-10-15 2004-07-23 Plastic Omnium Cie Dispositif de securite pour une seringue
EP1359479A1 (fr) * 2002-05-02 2003-11-05 Zenith International SA Pièce d'horlogerie à seconde foudroyante
US7247151B2 (en) * 2002-05-09 2007-07-24 Adam Slawson Injector with shielded needle
US8062252B2 (en) 2005-02-18 2011-11-22 Becton, Dickinson And Company Safety shield system for a syringe
US8372044B2 (en) 2005-05-20 2013-02-12 Safety Syringes, Inc. Syringe with needle guard injection device
CA2624895C (en) * 2005-10-11 2014-12-30 Thomson Licensing Dvd replication system and method
US7637889B2 (en) * 2006-11-15 2009-12-29 Glynntech, Inc. Drug delivery device with sliding valve and methodology
US8382713B2 (en) * 2006-12-11 2013-02-26 Kenergy Scientific, Inc. Drug delivery device and methodology
JP2009240411A (ja) * 2008-03-28 2009-10-22 Terumo Corp 医薬品容器
WO2009148969A1 (en) * 2008-06-02 2009-12-10 Sta-Med, Llc Needle cover assembly for a syringe
US8162882B2 (en) 2010-06-23 2012-04-24 Sta-Med, Llc Automatic-locking safety needle covers and methods of use and manufacture
WO2012166746A1 (en) 2011-05-31 2012-12-06 Sta-Med, Llc Blood collection safety devices and methods of use and manufacture
US9248242B2 (en) * 2012-04-20 2016-02-02 Safety Syringes, Inc. Anti-needle stick safety device for injection device
USD765838S1 (en) 2015-03-26 2016-09-06 Tech Group Europe Limited Syringe retention clip
US11587463B2 (en) 2016-10-18 2023-02-21 Merck Sharp & Dohme Llc Patient training device for use with a safety syringe injector
GB201706697D0 (en) 2017-04-27 2017-06-14 Ucb Biopharma Sprl Cap for an injector
US11701470B2 (en) * 2018-02-19 2023-07-18 Becton Dickinson France Injection system comprising a syringe and a protective assembly
US10675416B2 (en) * 2018-08-17 2020-06-09 David Harold Kovacs Retractable syringe
GB2577549B (en) * 2018-09-28 2021-08-04 Owen Mumford Ltd Injection device with commit feature
CN111905193A (zh) * 2020-09-15 2020-11-10 山东威高普瑞医药包装有限公司 一种注射装置

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FR2648716B1 (fr) * 1989-06-27 1991-09-13 Guerineau Jean Seringue a usage unique. combine seringue-aiguille, auto-escamotable dans un fourreau de protection
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US6719730B2 (en) * 1998-04-17 2004-04-13 Becton, Dickinson And Company Safety shield system for prefilled syringes

Also Published As

Publication number Publication date
AU4048199A (en) 2000-06-26
US6872190B1 (en) 2005-03-29
EP1892004A2 (fr) 2008-02-27
ATE385818T1 (de) 2008-03-15
EP1329234A2 (fr) 2003-07-23
CA2361100A1 (fr) 2000-06-15
EP1329234B1 (fr) 2008-02-13
FR2787335B1 (fr) 2001-02-16
JP4125491B2 (ja) 2008-07-30
ATE288773T1 (de) 2005-02-15
EP1892004A3 (fr) 2008-03-26
EP1148904B1 (fr) 2005-02-09
DE69923706D1 (de) 2005-03-17
WO2000033900A1 (fr) 2000-06-15
DE69923706T2 (de) 2006-01-12
JP2002538853A (ja) 2002-11-19
EP1329234A3 (fr) 2003-08-20
DE69938157T2 (de) 2009-02-05
EP1148904A1 (fr) 2001-10-31
DE69938157D1 (de) 2008-03-27
FR2787335A1 (fr) 2000-06-23

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