EP1147118A4 - Substituted alpha-linked disaccharides - Google Patents

Substituted alpha-linked disaccharides

Info

Publication number
EP1147118A4
EP1147118A4 EP00906899A EP00906899A EP1147118A4 EP 1147118 A4 EP1147118 A4 EP 1147118A4 EP 00906899 A EP00906899 A EP 00906899A EP 00906899 A EP00906899 A EP 00906899A EP 1147118 A4 EP1147118 A4 EP 1147118A4
Authority
EP
European Patent Office
Prior art keywords
substituted alpha
linked disaccharides
disaccharides
linked
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00906899A
Other languages
German (de)
French (fr)
Other versions
EP1147118A1 (en
Inventor
Daniel Kahne
Min Ge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Princeton University filed Critical Princeton University
Publication of EP1147118A1 publication Critical patent/EP1147118A1/en
Publication of EP1147118A4 publication Critical patent/EP1147118A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EP00906899A 1999-01-12 2000-01-12 Substituted alpha-linked disaccharides Withdrawn EP1147118A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11559599P 1999-01-12 1999-01-12
US115595P 1999-01-12
PCT/US2000/000686 WO2000042052A1 (en) 1999-01-12 2000-01-12 Substituted alpha-linked disaccharides

Publications (2)

Publication Number Publication Date
EP1147118A1 EP1147118A1 (en) 2001-10-24
EP1147118A4 true EP1147118A4 (en) 2004-01-28

Family

ID=22362334

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00906899A Withdrawn EP1147118A4 (en) 1999-01-12 2000-01-12 Substituted alpha-linked disaccharides

Country Status (3)

Country Link
EP (1) EP1147118A4 (en)
AU (1) AU2848200A (en)
WO (1) WO2000042052A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1173193A4 (en) * 1999-04-02 2003-01-29 Univ Princeton Desleucyl glycopeptide antibiotics and methods of making same
US6699836B2 (en) 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0578112A2 (en) * 1992-07-03 1994-01-12 The Nisshin Oil Mills, Ltd. Disaccharide derivatives and processes for the preparation thereof
US5635612A (en) * 1993-02-23 1997-06-03 The Trustees Of Princeton University Method of forming multiple glycosidic linkages in a single step
WO1998000153A1 (en) * 1996-06-28 1998-01-08 Eli Lilly And Company Amides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4470976A (en) * 1983-08-29 1984-09-11 American Cyanamid Company Poly-cation salt of 4-O-polyhexaose-thio-arylene sulfates

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0578112A2 (en) * 1992-07-03 1994-01-12 The Nisshin Oil Mills, Ltd. Disaccharide derivatives and processes for the preparation thereof
US5635612A (en) * 1993-02-23 1997-06-03 The Trustees Of Princeton University Method of forming multiple glycosidic linkages in a single step
WO1998000153A1 (en) * 1996-06-28 1998-01-08 Eli Lilly And Company Amides

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
GE ET AL: "Vancomycin Derivatives that Inhibit Peptidoglycan Biosynthesis without Binding D-Ala-D-Ala", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 284, no. 5413, 16 April 1999 (1999-04-16), pages 507 - 511, XP002189915, ISSN: 0036-8075 *
HUTNY J ET AL: "ASSAY OF ALPHA-1,4-TRANSGLYCOSYLASE ACTIVITY WITH P-NITROPHENYL-N-MALTOSIDE AS SUBSTRATE", ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, POLISH ACADEMY OF SCIENCES, WROCLAW, PL, vol. 16, no. 4, 1968, pages 670 - 675, XP001062180, ISSN: 0004-069X *
MALABARBA A NICAS TI CIABATTI R: "Glycopeptide resistance in multiple antibiotic-resistant Gram-positive bacteria: a current challenge for novel semi-synthetic glycopeptide derivatives", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 32, no. 6, 1 June 1997 (1997-06-01), pages 459 - 478, XP004088458, ISSN: 0223-5234 *
NICOLAOU, K. C. ET AL: "Expeditious routes to evernitrose and vancosamine derivatives and synthesis of a model vancomycin aryl glycoside", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION ( 1998 ), 37(13/14), 1871-1874, 1998, XP002261776 *
See also references of WO0042052A1 *
ZEHAVI U ET AL: "ENZYMIC SYNTHESIS OF OLIGOSACCHARIDES ON A POLYMER SUPPORT LIGHT-SENSITIVE, SUBSTITUTED POLYACRYLAMIDE BEADS", CARBOHYDRATE RESEARCH, ELSEVIER SCIENTIFIC PUBLISHING COMPANY. AMSTERDAM, NL, vol. 124, no. 1, 1983, pages 23 - 34, XP000565754, ISSN: 0008-6215 *

Also Published As

Publication number Publication date
EP1147118A1 (en) 2001-10-24
WO2000042052A1 (en) 2000-07-20
AU2848200A (en) 2000-08-01

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Legal Events

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Inventor name: GE, MIN

Inventor name: KAHNE, DANIEL

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