EP1141301A2 - Sequence-determined dna fragments and corresponding polypeptides encoded thereby - Google Patents

Sequence-determined dna fragments and corresponding polypeptides encoded thereby

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Publication number
EP1141301A2
EP1141301A2 EP00901405A EP00901405A EP1141301A2 EP 1141301 A2 EP1141301 A2 EP 1141301A2 EP 00901405 A EP00901405 A EP 00901405A EP 00901405 A EP00901405 A EP 00901405A EP 1141301 A2 EP1141301 A2 EP 1141301A2
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EP
European Patent Office
Prior art keywords
seq
sequence
alignment
location
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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EP00901405A
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German (de)
French (fr)
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EP1141301A4 (en
Inventor
Nickolai Alexandrov
Vyacheslav Brover
Xianfeng Chen
Gopalakrishnan Subramanian
Maxim E. Troukhan
Liansheng Zheng
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Ceres Inc
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Ceres Inc
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Publication of EP1141301A2 publication Critical patent/EP1141301A2/en
Publication of EP1141301A4 publication Critical patent/EP1141301A4/en
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

Definitions

  • the present invention relates to isolated polynucleotides that encode all, or a portion of, a gene that is expressed and the corresponding polypeptide.
  • the present invention also relates to isolated polynucleotides that encode regulatory regions of genes.
  • the present invention comprises polynucleotides, such as complete cDNA sequences and/or sequences of genomic DNA encompassing complete genes, portions of genes, and/or intergenic regions, hereinafter collectively referred to as "Sequence-Determined DNA Fragments" (SDFs), from plants, particularly corn and Arabidopsis thaliana and polypeptides derived therefrom.
  • SDFs Sequence-Determined DNA Fragments
  • the SDFs span the entirety of a protein-coding segment.
  • the entirety of an mRNA is represented.
  • Other objects of the invention are the control sequences, such as but not limited to promoters, that are also represented by SDFs of the invention. Complements of any sequence of the invention are also considered part of the invention.
  • polynucleotides comprising exon sequences, polynucleotides comprising intron sequences, polynucleotides comprising introns together with exons, intron/exon junction sequences, 5' untranslated sequences, and 3' untranslated sequences of the SDFs of the present invention.
  • Polynucleotides representing the joinder of any exons described herein, in any arrangement, for example, to produce a sequence encoding any desirable amino acid sequence are within the scope of the invention.
  • the present invention also resides in probes useful for isolating and identifying nucleic acids that hybridize to an SDF of the invention.
  • the probes are typically of a length of 12 to 2000 nucleotides long; more typically, 15 to 200 nucleotides long; even more typically, 18 to 100 nucleotides long.
  • Yet another object of the invention is a method of isolating and/or identifying nucleic acids using the following steps:
  • the conditions for hybridization can be from low to moderate to high stringency conditions.
  • the sample can include a polynucleotide having a sequence unique in a plant genome. Probes and methods of the invention are useful, for example, without limitation, for mapping of genetic traits and/or for positional cloning of a desired portion of genomic DNA.
  • Probes and methods of the invention can also be used for detecting alternatively spliced messages within a species. Probes and methods of the invention can further be used to detect or isolate related genes in other plant species using genomic DNA (gDNA) and/or cDNA libraries. In some instances, especially when longer probes and low to moderate stringency hybridization conditions are used, the probe will hybridize to a plurality of cDNA and/or gDNA sequences of a plant. This approach is useful for isolating representatives of gene families which are identifiable by possession of a common functional domain in the gene product or which have common cis- acting regulatory sequences. This approach is also useful for identifying orthologous genes from other organisms, which can be more or less related to corn, Arabidopsis, or another plant.
  • the present invention also resides in constructs for modulating the expression of the genes comprised of all or a portion of an SDF.
  • the constructs comprise all or a portion of the expressed SDF, or of a complementary sequence.
  • Examples of constructs include ribozymes comprising RNA encoded by an SDF or by a sequence complementary thereto, antisense constructs, constructs comprising coding regions or parts thereof, constructs comprising promoters, introns, untranslated regions, etc.
  • the construct When inserted into a host cell the construct is, preferably, functionally integrated with or operatively linked to a heterologous polynucleotide.
  • a coding region from an SDF might be operably linked to a promoter that is functional in a plant.
  • the present invention also resides in host cells, including bacterial or yeast cells or plant cells, and transgenic plants that harbor constructs such as described above.
  • Another aspect of the invention relates to methods for modulating expression of specific genes in transgenic plants by expression of the structural gene component of the constructs, by regulation of expression of one or more endogenous genes in a transgenic plant or by suppression of expression of the polynucleotides of the invention in a transgenic plant.
  • Methods of modulation of gene expression include without limitation (1) inserting into a host cell additional copies of a polynucleotide comprising a coding sequence; (2) modulating an endogenous promoter in a host cell; (3) inserting antisense or ribozyme constructs into a host cell and (4) inserting into a host cell a polynucleotide comprising a sequence encoding a mutant, fragment, or fusion of the native polypeptides of the instant invention.
  • sequences of exemplary SDFs and polypeptides encoded thereby of the instant invention are listed in SEQ TABLES 1 and 2; annotation relevant to the sequences shown in SEQ TABLES 1 and 2 is presented in REF TABLES 1 and 2.
  • Each sequence corresponds to a Maximum Length cDNA Polynucleotide Sequence.
  • Each Maximum Length cDNA Polynucleotide Sequence corresponds to at least one sequence in SEQ TABLE 1 and 2.
  • REF TABLE 1 corresponds with SEQ TABLE 1;
  • REF TABLE 2 corresponds with SEQ TABLE 2.
  • REF TABLES 1 and 2 are Reference Tables which correlate each of the sequences and SEQ ID NOS in SEQ TABLES 1 and 2 with a corresponding Maximum Length cDNA Sequence (Ac) , Ceres
  • SEQ TABLES 1 and 2 are Sequence Tables containing the sequence of each nucleic acid and amino acid sequence.
  • each section begins by identifying the Maximum Length cDNA Polynucleotide Sequence, indicating a "Clone ID” that is a number used for identification purposes by the applicant and in some instances a "Public Genomic DNA” sequence, indicated by a "gi No” .
  • a public sequence is recited, there follows information about gene annotations such as predicted exons.
  • INIT denotes an initial exon.
  • INTR denotes an internal exon.
  • TERM denotes a terminal exon.
  • the cDNA MLS is identified by its SEQ ID NO ("Pat. Appln. SEQ ID NO") and the Ceres sequence identifier ("Ceres seq_id” ) , which is also merely an identifier useful for the applicant.
  • SEQ ID NO SEQ ID NO
  • Ceres seq_id Ceres sequence identifier
  • the designation of "Alternative transcription start sites” can include both positive and negative numbers. Positive numbers refer to the referenced SEQ ID NO directly. The positions indicated by negative numbers, if any, refer to positions in the public genomic sequences. In instances where there is a "Public
  • Genomic DNA the relevant genomic sequence can be found by direct reference to the nucleotide sequence indicated by the "gi" number shown for the Public Genomic DNA.
  • the relevant nucleotide sequence for alignment is the nucleotide sequence associated with the amino acid sequence designated by a "gi" number in the section (Dp).
  • the nucleotide sequence is found in GENBANK by clicking on the link in the National Center for Biotechnology Information Entrez database. The numbering is relative to position 1 as determined by aligning the first residue of the MLS cDNA sequence (SEQ ID NO *) with the genomic sequence corresponding to the relevant "gi" number.
  • Subsection (B) lists SEQ ID NOS and Ceres seq_ids for polypeptide sequences encoded by the cDNA sequence and the location of the start codon within the cDNA sequence that codes for the polypeptide. Subsection (B) also describes additional features within the polypeptide sequence. Subsection (C) provides information regarding identified domains (where present) within the polypeptide and (where present) a name for the polypeptide. Subsection (Dp) provides
  • “related” sequences are identified by a "gi” number and are amino acid sequences in the publicly accessible BLAST databases on the NCBI FTP web site (accessible at ncbi.nlm.gov/blast).
  • the database at the NCBI FTP site utilizes the "gi" identifiers to assign by NCBI a unique identifier for each sequence in the databases, thereby providing a non-redundant database for sequences from various databases, including GenBank, EMBL, DBBJ (DNA Database of Japan) and PDB (Brookhaven Protein Data Bank) .
  • (Ba) when present, describes a sequence as being considered plant-specific (i.e. a gene found only in a plant) or describes a bichemical activity for the protein encoded by the exemplary SDF.
  • Subsection (Dn) provides polynucleotide sequences (where present) related to the Maximum Length cDNA sequence .
  • the invention relates to (I) polynucleotides and methods of use thereof, such as IA. Probes, Primers and Substrates;
  • IB Methods of Detection and Isolation; B.l. Hybridization; B.2. Methods of Mapping; B.3. Southern Blotting; B.4. Isolating cDNA from Related Organisms;
  • polypeptides including, without limitation, native proteins, mutants, fragments, and fusions. Antibodies to said polypeptides are also disclosed.
  • the specification also discloses (III) methods of modulating polypeptide production or activity. Examples of such methods include (i) suppressed, (ii) enhanced, and (iii) directed expression.
  • the specification also discloses (IV) gene constructs and construction of expression vectors, including (IVA) coding sequences and (IVB) promoters, and (IVC) Signal Peptides, (V) transformation procedures to illustrate the invention by way of examples .
  • a number of the nucleotide sequences disclosed in SEQ TABLES 1 AND 2 herein as representative of the SDFs of the invention can be obtained by sequencing genomic DNA (gDNA) and/or cDNA from corn plants grown from HYBRID SEED # 35A19, purchased from Pioneer Hi-Bred International, Inc., Supply Management, P.O. Box 256, Johnston, Iowa 50131-0256.
  • Exemplified SDFs of the invention represent portions of the genome of corn or Arabidopsis and/or represent mRNA expressed from that genome.
  • the isolated nucleic acid of the invention also encompasses corresponding portions of the genome and/or cDNA complement of other organisms as described in detail below.
  • HYBRID SEED # 35A19 Male inflorescences and female (pre-and post-fertilization) inflorescences were isolated at various stages of development. Selection for poly (A) containing polysomal RNA was done using oligo d(T) cellulose columns, as described by Cox and Goldberg, "Plant Molecular Biology: A Practical Approach", pp. 1-35, Shaw ed., c. 1988 by IRL, Oxford.
  • Tissues were or each organ was individually pulverized and frozen in liquid nitrogen. Next, the samples were homogenized in the presence of detergents and then centrifuged. The debris and nuclei were removed from the sample and more detergents were added to the sample. The sample was centrifuged and the debris was removed. Then the sample was applied to a 2M sucrose cushion to isolate polysomes. The RNA was isolated by treatment with detergents and proteinase K followed by ethanol precipitation and centrifugation. The polysomal RNA from the different tissues was pooled according to the following mass ratios: 15/15/1 for male inflorescences, female inflorescences and root, respectively. The pooled material was then used for cDNA synthesis by the methods described below.
  • a number of the nucleotide sequences disclosed in SEQ TABLES 1 AND 2 herein as representative of the SDFs of the invention can also be obtained by sequencing genomic DNA from Arabidopsis thaliana , Wassilewskija ecotype or by sequencing cDNA obtained from mRNA from such plants as described below. This is a true breeding strain. Seeds of the plant are available from the Arabidopsis Biological Resource Center at the Ohio State University, under the accession number CS2360.
  • Arabidopsis cDNA clones having sequences presented in SEQ TABLES 1 AND 2 was polysomal RNA isolated from the top-most inflorescence tissues and roots of Arabidopsis thaliana Landsberg erecta (L. er.) also obtained from the Arabidopsis Biological Resource Center. Nine parts inflorescence to every part root was used, as measured by mass. Tissue was pulverized and exposed to liquid nitrogen. Next, the sample was homogenized in the presence of detergents and then centrifuged. The debris and nuclei were removed from the sample and more detergents were added to the sample. The sample was centrifuged ind the debris was removed and the sample was applied to a 2M sucrose cushion to isolate polysomal RNA.
  • mRNAs Following preparation of the mRNAs from various tissues as described above, selection of mRNA with intact 5' ends and specific attachment of an oligonucleotide tag to the 5' end of such mRNA was performed using either a chemical or enzymatic approach. Both techniques take advantage of the presence of the "cap" structure, which characterizes the 5' end of most intact mRNAs and which comprises a guanosine generally methylated once, at the 7 position.
  • the chemical modification approach involves the optional elimination of the 2', 3'-cis diol of the 3' terminal ribose, the oxidation of the 2', 3'-cis diol of the ribose linked to the cap of the 5' ends of the mRNAs into a dialdehyde, and the coupling of the such obtained dialdehyde to a derivatized oligonucleotide tag. Further detail regarding the chemical approaches for obtaining mRNAs having intact 5' ends are disclosed in International Application No. W096/34981 published
  • the oligonucleotide tag has a restriction enzyme site (e.g. an EcoRI site) therein to facilitate later cloning procedures.
  • a restriction enzyme site e.g. an EcoRI site
  • the integrity of the mRNA is examined by performing a Northern blot using a probe complementary to the oligonucleotide tag.
  • first strand cDNA synthesis is performed using an oligo-dT primer with reverse transcriptase.
  • This oligo-dT primer can contain an internal tag of at least 4 nucleotides, which can be different from one mRNA preparation to another.
  • Methylated dCTP is used for cDNA first strand synthesis to protect the internal EcoRI sites from digestion during subsequent steps.
  • the first strand cDNA is precipitated using isopropanol after removal of RNA by alkaline hydrolysis to eliminate residual primers.
  • Second strand cDNA synthesis is conducted using a DNA polymerase, such as Klenow fragment and a primer corresponding to the 5' end of the ligated oligonucleotide.
  • the primer is typically 20-25 bases in length.
  • Methylated dCTP is used for second strand synthesis in order to protect internal EcoRI sites in the cDNA from digestion during the cloning process.
  • the full-length cDNAs are cloned into a phagemid vector, such as pBlueScriptTM (Stratagene) .
  • the ends of the full-length cDNAs are blunted with T4 DNA polymerase (Biolabs) and the cDNA is digested with EcoRI. Since methylated dCTP is used during cDNA synthesis, the EcoRI site present in the tag is the only hemi-methylated site; hence the only site susceptible to EcoRI digestion.
  • an Hind III adapter is added tc the 3' end of full-length cDNAs .
  • the full-length cDNAs are then size fractionated using either exclusion chromatography (AcA, Biosepra) or electrophoretic separation which yields 3 to 6 different fractions.
  • the full-length cDNAs are then directionally cloned either into pBlueScriptTM using either the EcoRI and Smal restriction sites or, when the Hind III adapter is present in the full-length cDNAs, the EcoRI and Hind III restriction sites.
  • the ligation mixture is transformed, preferably by electroporation, into bacteria, which are then propagated under appropriate antibiotic selection. Clones containing the oligonucleotide tag attached to full-length cDNAs are selected as follows.
  • the plasmid cDNA libraries made as described above are purified (e.g. by a column available from Qiagen) .
  • a positive selection of the tagged clones is performed as follows. Briefly, in this selection procedure, the plasmid DNA is converted to single stranded DNA using phage FI gene II endonuclease in combination with an exonuclease (Chang et al.,
  • the single stranded DNA is hybridized with a biotinylated oligonucleotide having a sequence corresponding to the 3' end of the oligonucleotide tag.
  • the primer has a length of 20-25 bases.
  • Clones including a sequence complementary to the biotinylated oligonucleotide are selected by incubation with streptavidin coated magnetic beads followed by magnetic capture. After capture of the positive clones, the plasmid DNA is released from the magnetic beads and converted into double stranded DNA using a DNA polymerase such as ThermoSequenaseTM (obtained from Amersham Pharmacia Biotech) .
  • Protocols such as the Gene TrapperTM kit (Gibco BRL) ca be used.
  • the double stranded DNA is then transformed, preferably by electroporation, into bacteria.
  • the percentage of positive clones having the 5' tag oligonucleotide is typically estimated to be between 90 and 98% from dot blot analysis.
  • the Arabidopsis library was deposited at the American Type Culture Collection on January 7, 2000 as E-coli liba 010600" under the accession number
  • Sequence errors may arise in the normal course of determination of nucleotide sequences. Sequence errors can be corrected by obtaining seeds deposited under the accession numbers cited above, propagating them, isolating genomic DNA or appropriate mRNA from the resulting plants or seeds thereof, amplifying the relevant portion of the genomic DNA or mRNA using primers having a sequence that flanks the erroneous sequence, and sequencing the amplification product.
  • SDFs of the invention can be applied to substrates for use in array applications such as, but not limited to, assays of global gene expression, for example under varying conditions of development, growth conditions.
  • the arrays can also be used in diagnostic or forensic methods.
  • Probes and primers of the instant invention will hybridize to a polynucleotide comprising a sequence in SEQ TABLES 1 AND 2. Though many different nucleotide sequences can encode an amino acid sequence, in some instances, the sequences of SEQ TABLES 1 AND 2 are preferred for encoding polypeptides of the invention. However, the sequence of the probes and/or primers of the instant invention need not be identical to those in SEQ TABLES 1 AND 2 or the complements thereof. For example, some variation in probe or primer sequence and/or length can allow additional family members to be detected, as well as orthologous genes and more taxonomically distant related sequences. Similarly probes and/or primers of the invention can include additional nucleotides that serve as a label for detecting the formed duplex or for subsequent cloning purposes.
  • Probe length will vary depending on the application. For use as PCR primers, probes should be 12-40 nucleotides, preferably 18-30 nucleotides long. For use in mapping, probes should be 50 to 500 nucleotides, preferably 100-250 nucleotides long. For Southern hybridizations, probes as long as several kilobases can be used as explained below.
  • the probes and/or primers can be produced by synthetic procedures such as the triester method of Matteucci et al. J.
  • Probes and/or primers can be used for detection and/or isolation of polynucleotide sequences. Such polynucleotides are included in the subject matter of the invention. Depending on the stringency of the conditions under which these probes and/or primers are used, polynucleotides exhibiting a wide range of similarity to those in SEQ TABLES 1 AND 2 can be detected or isolated.
  • N is the length of the probe. This equation works well for probes 14 to 70 nucleotides in length that are identical to the target sequence.
  • the equation below for T m of DNA-DNA hybrids is useful for probes in the range of 50 to greater than 500 nucleotides, and for conditions that include an organic solvent (formamide) .
  • T-. 81 . 5 + 16 . 6 log ⁇ [Na + ] / ⁇ 1 + 0 . 7 [Na + ] ) ⁇ + 0 . 41 ( %G+C ) -500/L 0 . 63 ( % f orm ⁇ mide ) ( 2 )
  • T m of equation (2) is affected by the nature of the hybrid; for DNA-RNA hybrids T m is 10-15°C higher than calculated, for RNA-RNA hybrids T m is 20-25°C higher. Because the T m decreases about 1 °C for each 1% decrease in homology when a long probe is used (Bonner et al . , J. Mol . Biol .
  • Equation (2) is derived assuming equilibrium and therefore, hybridizations according to the present invention are most preferably performed under conditions of probe excess and for sufficient time to achieve equilibrium. The time required to reach equilibrium can be shortened by inclusion of a "hybridization accelerator" such as dextran sulfate or another high volume polymer in the hybridization buffer.
  • the practitioner When using SDFs to identify orthologous genes in other species, the practitioner will preferably adjust the amount of target DNA of each species so that, as nearly as is practical, the same number of genome equivalents are present for each species examined. This prevents faint signals from species having large genomes, and thus small numbers of genome equivalents per mass of DNA, from erroneously being interpreted as absence of the corresponding gene in the genome .
  • Hybridization of one nucleic acid to another constitutes a physical property that defines the subject SDF of the invention. Also, such hybridization imposes structural limitations on the pair. For example, for a probe molecule, given that the sequence of the probe nucleic acid is known and fixed, equation (2) indicates that the combined variation in GC content of the target DNA and mismatch between the probe and the hybridizing DNA is determined for any given hybridization buffer composition and T m .
  • the probes and/or primers of the instant invention can be used to detect or isolate nucleotides that are “identical” to the probes or primers.
  • Two nucleic acid sequences or polypeptides are said to be “identical” if the sequence of nucleotides or amino acid residues, respectively, in the two sequences is the same when aligned for maximum correspondence as described below.
  • the term "complementary to” is used herein to mean that the sequence can form a Watson-Crick base pair with a reference polynucleotide sequence.
  • Complementary sequences can include nucleotides, such as inosine, that neither disrupt Watson-Crick base pairing nor contribute to the pairing.
  • Optimal alignment of sequences for comparison may be conducted by the local homology algorithm of Smith and Waterman Add. APL . Ma th . 2:482 (1981), by the homology alignment algorithm of Needleman and Wunsch J. Mol . Biol . 48:443 (1970), by the search for similarity method of Pearson and Lipman Proc. Na tl . Acad. Sci . (USA) 85_: 2444 (1988), by computerized implementations of these algorithms (GAP, BESTFIT, BLAST, PASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group (GCG) , 575 Science Dr., Madison, WI), or by inspection. Given that two sequences have been identified for comparison, GAP and BESTFIT are preferably employed to determine their optimal alignment. Typically, the default values of 5.00 for gap weight and 0.30 for gap weight length are used.
  • the probes and/or primers of the invention can also be used to detect and/or isolate polynucleotides exhibiting at least 80% sequence identity with the sequences of SEQ TABLES 1 AND 2 or fragments thereof.
  • Percentage of sequence identity is determined by comparing two optimally aligned sequences over a comparison window, wherein the portion of the polynucleotide sequence in the comparison window may comprise additions or deletions
  • the percentage is calculated by determining the number of positions at which the identical nucleic acid base or amino acid residue occurs in both sequences to yield the number of matched positions, dividing the number of matched positions by the total number of positions in the window of comparison and multiplying the result by 100 to yield the percentage of sequence identity. "Percentage of sequence identity" can be determined by the algorithms described above.
  • substantially identical between polynucleotide or polypeptide sequences refers to polynucleotide or polypeptide comprising a sequence that has at least 80% sequence identity, preferably at least 85%, more preferably at least 90% and most preferably at least 95%, even more preferably, at least 96%, 97%, 98% or 99% sequence identity compared to a reference sequence using the programs.
  • Isolated polynucleotides within the scope of the invention also include allelic variants of the specific sequences presented in SEQ TABLES 1 AND 2.
  • An "allelic variant” is a sequence that is a variant from that of the SDF, but represents the same chromosomal locus in the organism. Allelic variants can arise by normal genetic variation in a population. Allelic variants can also be produced by genetic engineering methods. An allelic variant can be one that is found in a naturally occurring plant, including a cultivar or ecotype. A silent allele can give rise to phenotypic and expression profiles. An allelic variant may or may not give rise to a phenotypic change, and may or may not be expressed. An expressed allele can result in a detectable change in the phenotype of the trait represented by the locus. Allelic variations can occur in any portion of the gene sequence, including regulatory regions as well as structural regions.
  • degeneracy of the genetic code provides the possibility to substitute at least one base of the base sequence of a gene with a different base without causing the amino acid sequence of the polypeptide produced from the gene to be changed.
  • the DNA of the present invention may also have any base sequence that has been changed from a sequence in SEQ TABLES 1 AND 2 by substitution in accordance with degeneracy of genetic code.
  • the isolated SDF DNA of the invention can be used to create various types of genetic and physical maps of the genome of corn, Arabidopsis or other plants. Some SDFs may be absolutely associated with particular phenotypic traits, allowing construction of gross genetic maps. While not all SDFs will immediately be associated with a phenotype, all SDFs can be used as probes for identifying polymorphisms associated with phenotypes of interest. Briefly, total DNA is isolated from individuals and is subsequently cleaved with one or more restriction enzymes, separated according to mass, transferred to a solid support, hybridized with SDF DNA and the pattern of fragments compared.
  • Polymorphisms associated with a particular SDF are visualized as differences in the size of fragments produced between individual DNA samples after digestion with a particular restriction enzyme and hybridization with the SDF.
  • linkage studies can be conducted. Recombinants produced are analyzed using the same restriction enzyme/hybridization procedure. After identification of many polymorphisms using SDF sequences, linkage studies can be conducted by using the individuals showing polymorphisms as parents in crossing programs. F2 progeny recombinants or recombinant inbreds, for example, are then analyzed using the same restriction enzyme/hybridization procedure.
  • the order of DNA polymorphisms along the chromosomes can be inferred based on the frequency with which they are inherited together versus independently. The closer two polymorphisms are together in a chromosome the higher the probability that they are inherited together. Integration of the relative positions of all the polymorphisms and associated marker SDFs produces a genetic map of the species, where the distances between markers reflect the recombination frequencies in that chromosome segment.
  • this procedure is not limited to plants and can be used for other organisms (such as yeast) or for individual cells .
  • SDFs of the present invention can also be used for simple sequence repeat (SSR) mapping.
  • SSR simple sequence repeat
  • SSR mapping can be achieved using various methods.
  • polymorphisms are identified when sequence specific probes flanking an SSR contained within an SDF are made and used in polymerase chain reaction (PCR) assays with template DNA from two or more individuals of interest.
  • PCR polymerase chain reaction
  • a change in the number of tandem repeats between the SSR-flanking sequence produces differently sized fragments (U.S. Patent 5,766,847).
  • polymorphisms can be identified by using the PCR fragment produced from the SSR-flanking sequence specific primer reaction as a probe against Southern blots representing different individuals (U.H. Refseth et al., (1997) Electrophoresis 18: 1519).
  • QTLs Quantitative Trait Loci
  • Many important crop traits such as the solids content of tomatoes, are quantitative traits and result from the combined interactions of several genes. These genes reside at different loci in the genome, oftentimes on different chromosomes, and generally exhibit multiple alleles at each locus.
  • the SDFs of the invention can be used to identify QTLs and isolate specific alleles as described by de Vicente and Tanksley (Genetics 134:585 (1993)). In addition to isolating QTL alleles present crop species, the SDFs of the invention can also be used to isolate alleles from the corresponding QTL of wild relatives.
  • Transgenic plants having various combinations of QTL alleles can then be created and the effects of the combinations measured. Once an ideal allele combination has been identified, crop improvement can be accomplished either through biotechnological means or by directed conventional breeding programs (for review see Tanksley and McCouch, Science
  • the SDFs can be used to help create physical maps of the genome of corn, Arabidopsis and related species. Where SDFs have been ordered on a genetic map, as described above, then SDFs can be used as probes to discover which clones in large libraries of plant DNA fragments in YACs, BACs, etc. contain the same SDF or similar sequences, thereby facilitating the assignment of the large DNA fragments to chromosomal positions. Subsequently, the large BACs, YACs, etc. can be ordered unambiguously by more detailed studies of their sequence composition (e.g. Marra et al.
  • any individual can be genotyped. These individual genotypes can be used for the identification of particular cultivars, varieties, lines, ecotypes and genetically modified plants or can serve as tools for subsequent genetic studies involving multiple phenotypic traits.
  • sequences from SEQ TABLES 1 AND 2 can be used as probes for various hybridization techniques. These techniques are useful for detecting target polynucleotides in a sample or for determining whether transgenic plants, seeds or host cells harbor a gene or sequence of interest and thus might be expected to exhibit a particular trait or phenotype.
  • the hybridization of the SDFs of the invention to nucleic acids obtained from other organisms can be used to identify orthologous genes from other species and/or additional members of gene families either in the same or different species.
  • a Southern blot of genomic DNA provides description of isolated DNA fragments that comprise the orthologous genes or additional members of the gene families. That is, given such data, one of ordinary skill in the art could distinguish the isolated DNA fragments by their size together with the restriction sites at each end and by the property of hybridizing with the SDF probe under the stated conditions.
  • the SDFs from the invention can be used to isolate additional members of gene families from the same species and/or orthologous genes from different species.
  • transgenic plants having various combinations of alleles can be created and the effects of the combinations measured. Once a more favorable ideal allele combination has been identified, crop improvement can be accomplished either through biotechnological means or by directed conventional breeding programs (Tanksley et al. Science 277:1063(1997) ) .
  • results from hybridizations of the SDFs of the invention to Southern blots containing DNA from another species can also be used to generate restriction fragment maps for the corresponding genomic regions. These maps provide map provides additional information about the relative positions of restriction sites within fragments, further distinguishing mapped DNA from the remainder of the genome. Physical maps can be made by digesting genomic DNA with different combinations of restriction enzymes.
  • Probes for Southern blotting to distinguish individual restriction fragments can range in size from 15 to 20 nucleotides to several thousand nucleotides. More preferably, the probe is 100 to 1000 nucleotides long for identifying members of a gene family when it is found that repetitive sequences would complicate the hybridization. For identifying an entire corresponding gene in another species, the probe is more preferably the length of the gene, typically 2000 to 10,000 nucleotides, but probes 50-1,000 nucleotides long might be used. Some genes, however, might require probes up to 15,000 nucleotides long or overlapping probes constituting the full-length sequence to span their lengths.
  • the probe be homogeneous with respect to its sequence, that is not necessary.
  • a probe representing members of a gene family having diverse sequences can be generated using PCR to amplify genomic DNA or RNA templates using primers derived from SDFs that include sequences that define the gene family.
  • the probe for Southern blotting most preferably would be the genomic copy of the probe gene. This allows all elements of the gene to be identified in the other species.
  • the next most preferable probe is a cDNA spanning the entire coding sequence, which allows all of the mRNA-coding portion of the gene to be identified; in this case it is possible that some introns in the gene might be missed.
  • Probes for Southern blotting can easily be generated from SDFs by making primers having the sequence at the ends of the SDF and using corn or Arabidopsis genomic DNA as a template. In instances where the SDF includes sequence conserved among species, primers including the conserved sequence can be used for PCR with genomic DNA from a species of interest to obtain a probe.
  • the SDF includes a domain of interest
  • that portion of the SDF can be used to make primers and, with appropriate template DNA, used to make a probe to identify genes containing the domain.
  • the PCR products can be resolved, for example by gel electrophoresis, and cloned and/or sequenced. In this manner, the variants of the domain among members of a gene family, both within and across species, can be examined.
  • B.4.1 Isolating DNA from Related Organisms The SDFs of the invention can be used to isolate the corresponding DNA from other organisms. Either cDNA or genomic DNA can be isolated.
  • a lambda, cosmid, BAC or YAC, or other large insert genomic library from the plant of interest can be constructed using standard molecular biology techniques as described in detail by Sambrook et al. 1989 (Molecular Cloning: A Laboratory Manual, 2 nd ed. Cold Spring Harbor Laboratory Press, New York) and by Ausubel et al. 1992 (Current Protocols in Molecular Biology, Greene Publishing, New York) .
  • recombinant lambda clones are plated out on appropriate bacterial medium using an appropriate E. coli host strain.
  • the resulting plaques are lifted from the plates using nylon or nitrocellulose filters.
  • the plaque lifts are processed through denaturation, neutralization, and washing treatments following the standard protocols outlined by Ausubel et al. (1992).
  • the plaque lifts are hybridized to either radioactively labeled or non- radioactively labeled SDF DNA at room temperature for about 16 hours, usually in the presence of 50% formamide and 5X SSC (sodium chloride and sodium citrate) buffer and blocking reagents.
  • formamide and 5X SSC sodium chloride and sodium citrate
  • the plaque lifts are then washed at 42°C with 1% Sodium Dodecyl Sulfate (SDS) and at a particular concentration of SSC.
  • SSC concentration used is dependent upon the stringency at which hybridization occurred in the initial Southern blot analysis performed. For example, if a fragment hybridized under medium stringency (e.g., Tm - 20°C), then this condition is maintained or preferably adjusted to a less stringent condition (e.g., Tm- 30°C) to wash the plaque lifts.
  • Positive clones show detectable hybridization e.g., by exposure to X-ray films or chromogen formation.
  • the positive clones are then subsequently isolated for purification using the same general protocol outlined above. Once the clone is purified, restriction analysis can be conducted to narrow the region corresponding to the gene of interest. The restriction analysis and succeeding subcloning steps can be done using procedures described by, for example Sambrook et al. (1989) cited above.
  • the procedures outlined for the lambda library are essentially similar except the YAC clones are harbored in bacterial colonies.
  • the YAC clones are plated out at reasonable density on nitrocellulose or nylon filters supported by appropriate bacterial medium in petri plates.
  • the filters are processed through the denaturation, neutralization, and washing steps following the procedures of Ausubel et al. 1992.
  • the same hybridization procedures for lambda library screening are followed.
  • the library can be constructed in a lambda vector appropriate for cloning cDNA such as ⁇ gtll.
  • the cDNA library can be made in a plasmid vector.
  • cDNA for cloning can be prepared by any of the methods known in the art, but is preferably prepared as described above.
  • a cDNA library will include a high proportion of full-length clones.
  • Probes and primers of the invention can be used to identify and/or isolate polynucleotides related to those in SEQ
  • orthologous genes a gene that has a high degree of sequence similarity, often along the entire length of the coding portion of the gene, and also encodes a gene product that performs a similar function in the organism.
  • orthologous genes may be distinguished from homologous genes in that homologous genes share sequence similarity but often only in a portion of the sequence, which often represents a functional domain such as a tyrosine kinase activity, a DNA binding domain, or the like.
  • the functional activities of homologous genes are not necessarily the same, but are the same for orthologous genes.
  • the degree of identity is a function of evolutionary separation and, in closely related species, the degree of identity can be 98 to 100%.
  • the amino acid sequence of a protein encoded by an orthologous gene can be less than 75% identical, but tends to be at least75% or at least 80% identical, more preferably at least 90%, most preferably at least 95% identical to the amino acid sequence of the reference protein.
  • the probes are hybridized to nucleic acids from a species of interest under low stringency conditions and blots are then washed under conditions of increasing stringency. It is preferable that the wash stringency be such that sequences that are 85 to 100% identical will hybridize. More preferably, sequences 90 to 100% identical will hybridize and most preferably only sequences greater than 95% identical will hybridize.
  • the low stringency condition is preferably one where sequences containing as much as 40-45% mismatches will be able to hybridize. This condition is established by T m - 40°C to Tm - 48°C ( see below) .
  • amino acid sequences that are identical can be encoded by DNA sequences as little as 67% identical.
  • Identification of the relationship of nucleotide or amino acid sequences among plant species can be done by comparison of the subject nucleotide or amino acid sequence to the sequences of SDFs of the present application presented in SEQ TABLES 1 and 2.
  • the SDFs of the invention can also be used as probes to search for genes that are related to the SDF within a species.
  • Such related genes are typically considered to be members of a "gene family.”
  • the sequence similarity will often be concentrated into one or a few portions of the sequence.
  • the portions of similar sequence that define the gene family typically encode a portion of a protein or RNA that has an enzymatic or structural function.
  • the degree of identity in the amino acid sequence of the domain that defines the gene family is preferably at least 70%, more preferably 80 to 95%, most preferably 85 to 99%.
  • a "low stringency" hybridization is usually performed, but this will depend upon the size, distribution and degree of sequence divergence of domains that define the gene family.
  • SDFs encompassing regulatory regions can be used to identify "coordinately expressed" genes by using the regulatory region portion of the SDF as a probe.
  • the SDFs are identified as being expressed from genes that confer a particular phenotype, then the SDFs can also be used as probes to assay plants of different species for those phenotypes.
  • a well-known instance is the FLAVOR-SAVORTM tomato, in which the gene encoding ACC synthase is inactivated by an antisense approach, thus delaying softening of the fruit after ripening. See for example, U.S. Patent No. 5,859,330; U.S. Patent No. 5,723,766; Oeller, et al, Science, 254:437-439(1991); and Hamilton et al, Na ture, 346:284-287 (1990).
  • timing of flowering can be controlled by suppression of the FLOWERING LOCUS C; high levels of this transcript are associated with late flowering, while absence of FLC is associated with early flowering (S.D. Michaels et al., Plant Cell 11:949 (1999).
  • the transition of apical meristem from production of leaves with associated shoots to flowering is regulated by TERMINAL FLOWER1 , APETALA1 and LEAFY.
  • TFL1 expression S.J. Liljegren, Plan t Cell 11:1007 (1999)
  • dominant negative mutant proteins are useful tools for research, for example when a dominant negative mutation of a receptor is used to constitutively activate or suppress a signal transduction cascade, allowing examination of the phenotype and thus the trait (s) controlled by that receptor and pathway.
  • the introduced sequence need not be perfectly identical to a sequence of the target endogenous gene.
  • the introduced polynucleotide sequence will typically be at least substantially identical (as determined above) to the target endogenous sequence.
  • SDFs in SEQ TABLES 1 AND 2 represent sequences that are expressed in corn and/or Arabidopsis .
  • the invention includes using these sequences to generate antisense constructs to inhibit transcription and/or translation of said SDFs, typically in a plant cell.
  • a polynucleotide segment from the desired gene that can hybridize to the mRNA expressed from the desired gene (the "antisense segment") is operably linked to a promoter such that the antisense strand of RNA will be transcribed when the construct is present in a host cell.
  • a regulated promoter can be used in the construct to control transcription of the antisense segment so that transcription occurs only under desired circumstances.
  • the antisense segment to be introduced generally will be substantially identical to at least a portion of the endogenous gene or genes to be repressed. The sequence, however, need not be perfectly identical to inhibit expression. Further, the antisense product may hybridize to the untranslated region instead of or in addition to the coding portion of the gene.
  • the vectors of the present invention can be designed such that the inhibitory effect applies to other proteins within a family of genes exhibiting homology or substantial homology to the target gene.
  • the introduced antisense segment sequence also need not be full length relative to either the primary transcription product or fully processed mRNA. Generally, higher sequence identity can be used to compensate for the use of a shorter sequence. Furthermore, the introduced sequence need not have the same intron or exon pattern, and homology of non-coding segments may be equally effective. Normally, a sequence of between about 30 or 40 nucleotides and the full length of the transcript should be used, though a sequence of at least about 100 nucleotides is preferred, a sequence of at least about 200 nucleotides is more preferred, and a sequence of at least about 500 nucleotides is especially preferred.
  • Ribozymes can also be used to inhibit expression of genes by suppressing the translation of the mRNA into a polypeptide. It is possible to design ribozymes that specifically pair with virtually any target RNA and cleave the phosphodiester backbone at a specific location, thereby functionally inactivating the target RNA. In carrying out this cleavage, the ribozyme is not itself altered, and is thus capable of recycling and cleaving other molecules, making it a true enzyme. The inclusion of ribozyme sequences within antisense RNAs confers RNA-cleaving activity upon them, thereby increasing the activity of the constructs.
  • ribozymes are derived from a number of small circular RNAs, which are capable of self-cleavage and replication in plants. The RNAs replicate either alone
  • RNAs viroid RNAs
  • helper virus satellite RNAs
  • RNAs from avocado sunblotch viroid examples include RNAs from avocado sunblotch viroid and the satellite RNAs from tobacco ringspot virus, lucerne transient streak virus, velvet tobacco mottle virus, solanum nodiflorum mottle virus and subterranean clover mottle virus.
  • the design and use of target RNA-specific ribozymes is described in Haselhoff et al . Nature, 334:585 (1988).
  • the ribozyme sequence portion necessary for pairing need not be identical to the target nucleotides to be cleaved, nor identical to the sequences in SEQ TABLES 1 AND 2.
  • the sequence in the ribozyme capable of binding to the target sequence exhibits substantial sequence identity to a sequence in SEQ TABLES 1 AND 2 or the complement thereof, or to a portion of said sequence or complement.
  • the ribozyme sequence also need not be full length relative to either the primary transcription product or fully processed mRNA.
  • the ribozyme can be equally effective in inhibiting mRNA translation by cleaving either in the untranslated or coding regions. Generally, higher sequence identity can be used to compensate for the use of a shorter sequence.
  • the introduced sequence need not have the same intron or exon pattern, and homology of non-coding segments may be equally effective.
  • Another method of suppression is by introducing an exogenous copy of the gene to be suppressed.
  • Introduction of expression cassettes in which a nucleic acid is configured in the sense orientation with respect to the promoter into the chromosome of a plant or by a self-replicating virus has been shown to be an effective means by which to induce degradation of mRNAs of target genes.
  • this method to modulate expression of endogenous genes see, Napoli et al., The Plant Cell 2:279 (1990), and U.S. Patents Nos.
  • the introduced sequence generally will be substantially identical to the endogenous sequence intended to be inactivated.
  • the minimal identity will typically be greater than about 65%, but a higher identity might exert a more effective repression of expression of the endogenous sequences.
  • Sequence identity of more than about 80% is preferred, though about 95% to absolute identity would be most preferred. As with antisense regulation, the effect would likely apply to any other proteins within a similar family of genes exhibiting homology or substantial homology to the suppressing sequence.
  • Another means of suppressing gene expression is to insert a polynucleotide into the gene of interest to disrupt transcription or translation of the gene.
  • Low frequency homologous recombination can be used to target a polynucleotide insert to a gene by flanking the polynucleotide insert with sequences that are substantially similar to the gene to be disrupted. Sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto can be used for homologous recombination.
  • random insertion of polynucleotides into a host cell genome can also be used to disrupt the gene of interest. Azpiroz-Leehan et al., Trends in Genetics 13: 152 (1997).
  • screening for clones from a library containing random insertions is preferred to identifying those that have polynucleotides inserted into the gene of interest. Such screening can be performed using probes and/or primers described above based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto. The screening can also be performed by selecting clones or Ri plants having a desired phenotype.
  • constructs described in the methods under I.C. above can be used to determine the function of the polypeptide encoded by the gene that is targeted by the constructs.
  • the host cell or organisms such as a plant, may produce phenotypic changes as compared to a wild-type cell or organism.
  • vi tro assays can be used to determine if any biological activity, such as calcium flux, DNA transcription, nucleotide incorporation, etc., are being modulated by the down-regulation of the targeted gene.
  • SDFs of the invention representing transcription activation and DNA binding domains can be assembled into hybrid transcriptional activators. These hybrid transcriptional activators can be used with their corresponding DNA elements (i.e., those bound by the DNA-binding SDFs) to effect coordinated expression of desired genes (J.J. Schwarz et al., Mol . Cell . Biol . 12:266 (1992), A. Martinez et al., Mol . Gen . Genet . 261:546 (1999)).
  • the SDFs of the invention can also be used in the two- hybrid genetic systems to identify networks of protein- protein interactions (L.
  • the SDFs of the invention can also be used in various expression display methods to identify important protein-DNA interactions (e.g. B. Luo et al., J. Mol . Biol . 266: 479 (1997) ) .
  • the SDFs of the invention are also useful as structural or regulatory sequences in a construct for modulating the expression of the corresponding gene in a plant or other organism, e.g. a symbiotic bacterium.
  • promoter sequences represented in SEQ TABLES 1 AND 2 can be useful in directing expression of coding sequences either as constitutive promoters or to direct expression in particular cell types, tissues, or organs or in response to environmental stimuli.
  • promoter refers to a region ofe-3? sequence determinants located upstream or downstream from the start of transcription and which are involved in recognition and binding of RNA polymerase and other proteins to initiate transcription.
  • a "plant promoter” is a promoter capable of initiating transcription in plant cells and can be used to drive expression of a translated portion of an SDF. Such promoters need not be of plant origin.
  • promoters derived from plant viruses such as the CaMV35S promoter or from Agrobacterium tumefaciens such as the T-DNA promoters, can be plant promoters.
  • a typical example of a constitutive promoter of plant origin is the promoter of the cowpea trypsin inhibitor gene.
  • Typical examples of temporal and/or tissue specific promoters of plant origin that can be used with the polynucleotides of the present invention, are: PTA29, a promoter which is capable of driving gene expression specifically in tapetum and only during anther development
  • promoters that have a high preference of driving gene expression in the specified tissue and/or at the specified time during the concerned tissue or organ development.
  • high preference is meant at least 3-fold, preferably 5-fold, more preferably at least 10-fold still more preferably at least 20-fold, 50-fold or 100-fold increase in expression in the desired tissue over the expression in any undesired tissue.
  • a typical example of an inducible promoter which can be utilized with the polynucleotides of the present invention, is PARSKl, the promoter from the Arabidopsis gene encoding a serine-threonine kinase enzyme, and which promoter is induced by dehydration, abscissic acid and sodium chloride (Wang and Goodman, Plant J. 8:37 (1995)).
  • a promoter is likely to be a relatively small portion of a genomic DNA (gDNA) sequence located in the first 2000 nucleotides upstream from an initial exon identified in a gDNA sequence or initial "ATG” or methionine codon in a corresponding cDNA or mRNA sequence.
  • gDNA genomic DNA
  • Such promoters are more likely to be found in the first 1000 nucleotides upstream of an initial ATG or methionine codon of a cDNA sequence corresponding to a gDNA sequence.
  • the promoter is usually located upstream of the transcription start site.
  • Such a start site is located at the first exon predicted in the OCKHAM-cDNA predictions.
  • the transcription start site is the first nucleotide of the 5' most exon, if the predictions are in the plus (+) strand, or the 3' most if the predictions are in the minus (-) strand.
  • Alternative transcription start sites may be located between the first nucleotide of the 5' most exon (or the 3' most exon in the minus (-) strand) and the initial ATG or methionine codon in the cDNA sequence.
  • the portions of a particular gDNA sequence that function as a promoter in a plant cell will preferably be found to hybridize at medium or high stringency to gDNA sequences presented in SEQ TABLES 1 AND 2.
  • Promoters are generally modular in nature. Short DNA sequences representing binding sites for proteins can be separated from each other by intervening sequences of varying length. For example, within a particular functional module protein binding sites may be constituted by regions of 5 to 60, preferably 10 to 30, more preferably 10 to 20 nucleotides. Within such binding sites, there are typically 2 to 6 nucleotides that specifically contact amino acids of the nucleic acid binding protein. The protein binding sites are usually separated from each other by 10 to several hundred nucleotides, typically by 15 to 150 nucleotides, often by 20 to 50 nucleotides. DNA binding sites in promoter elements often display dyad symmetry in their sequence. Often elements binding several different proteins, and/or a plurality of sites that bind the same protein, will be combined in a region of 100 to 1000 basepairs.
  • Elements that have transcription regulatory function can be isolated from their corresponding endogenous gene, or the desired sequence can be synthesized, and recombined in constructs to direct expression of a structural gene in a desired tissue-specific, temporal-specific or other desired manner of inducibility or suppression.
  • hybridizations are performed to identify or isolate elements of a promoter by hybridization to the long sequences presented in SEQ TABLES 1 AND 2, conditions should be adjusted to account for the above- described nature of promoters. For example short probes, constituting the element sought, should be used under low temperature and/or high salt conditions. When long probes, which might include several promoter elements are used, low to medium stringency conditions are preferred when hybridizing to promoters across species.
  • Promoters can consist of a "basal promoter" that functions as a site for assembly of a transcription complex comprising an RNA polymerase, for example RNA polymerase II.
  • a typical transcription complex will include additional factors such as TF ⁇ I B, TFnD, and TF TI E. Of these, TF D appears to be the only one to bind DNA directly.
  • Basal promoters frequently include a "TATA box" element usually located _ ⁇ tween 20 and 35 nucleotides upstream from the site of initiation of transcription.
  • Basal promoters also sometimes include a "CCAAT box” element (typically a sequence CCAAT) and/or a GGGCG sequence, usually located between 40 and 200 nucleotides, preferably 60 to 120 nucleotides, upstream from the start site of transcription.
  • CCAAT box typically a sequence CCAAT
  • GGGCG sequence usually located between 40 and 200 nucleotides, preferably 60 to 120 nucleotides, upstream from the start site of transcription.
  • the promoter might also contain one or more "enhancers” and/or “suppressors” that function as binding sites for additional transcription factors that have the function of modulating the level of transcription with respect to tissue specificity of transcription, transcriptional responses to particular environmental or nutritional factors, and the like.
  • nucleotide sequence of an SDF functions as a promoter or portion of a promoter
  • nucleotide substitutions, insertions or deletions that do not substantially affect the binding of relevant DNA binding proteins would be considered equivalent to the exemplified nucleotide sequence. It is envisioned that there are instances where it is desirable to decrease the binding of relevant DNA binding proteins to "silence" or “down-regulate” a promoter, or conversely to increase the binding of relevant
  • DNA binding proteins to "enhance” or "up-regulate” a promoter.
  • polynucleotides representing changes to the nucleotide sequence of the DNA-protein contact region by insertion of additional nucleotides, changes to identity of relevant nucleotides, including use of chemically-modified bases, or deletion of one or more nucleotides are considered encompassed by the present invention.
  • Promoter function can be assayed by methods known in the art, preferably by measuring activity of a reporter gene operatively linked to the sequence being tested for promoter function. Examples of reporter genes include those encoding luciferase, green fluorescent protein, G.'S, neo, cat and bar.
  • UTR sequences include introns and 5' or 3' untranslated regions ( 5' UTRs or 3' UTRs) .
  • Portions of the sequences shown in SEQ TABLES 1 AND 2 can comprise UTRs and introns or intron/exon junctions.
  • SDFs can have regulatory functions related to, for example, translation rate and mRNA stability.
  • these portions of SDFs can be isolated for use as elements of gene constructs for expression of polynucleotides encoding desired polypeptides.
  • Introns of genomic DNA segments might also have regulatory functions. Sometimes promoter elements, especially transcription enhancer or suppressor elements, are found within introns. Also, elements related to stability of heteronuclear RNA and efficiency of transport to the cytoplasm for translation can be found in intron elements. Thus, these segments can also find use as elements of expression vectors intended for use to transform plants.
  • introns and UTR sequences and intron/exon junctions can vary from those shown in SEQ TABLES
  • Isolated polynucleotides of the invention can include coding sequences that encode polypeptides comprising an amino acid sequence encoded by a sequences in SEQ TABLES 1 AND 2 or an amino acid sequence presented in SEQ TABLES 1 AND 2.
  • a nucleotide sequence "encodes" a polypeptide if a cell
  • an isolated nucleic acid that "encodes" a particular amino acid sequence can be a genomic sequence comprising exons and introns or a cDNA sequence that represents the product of splicing thereof.
  • An isolated nucleic acid "encoding an amino acid sequence” also encompasses heteronuclear RNA, which contains sequences that are spliced out during expression, and mRNA, which lacks those sequences. Coding sequences can be constructed using chemical synthesis techniques or by isolating coding sequences or by modifying such synthesized or isolated coding sequences as described above.
  • the isolated polynucleotides can be variant polynucleotides that encode mutants, fragments, and fusions of those native proteins. Such polypeptides are described below in part II.
  • the number of substitutions, deletions or insertions is preferably less than 20%, more preferably less than 15%; even more preferably less than 10%, 5%, 3% or 1% of the number of nucleotides comprising a particularly exemplified sequence.
  • nucleotide sequence changes that result in 1 to 10, more preferably 1 to 5 and most preferably 1 to 3 amino acid insertions, deletions or substitutions will not greatly affect the function of an encoded polypeptide.
  • the most preferred embodiments are those wherein 1 to 20, preferably 1 to 10, most preferably 1 to 5 nucleotides are added to, deleted from and/or substituted in the sequences specifically disclosed in SEQ TABLES 1 AND 2.
  • Insertions or deletions in polynucleotides intended to be used for encoding a polypeptide should preserve the reading frame. This consideration is not so important in instances when the polynucleotide is intended to be used as a hybridization probe.
  • Polypeptides within the scope of the invention include both native proteins as well as mutants, fragments, and fusions thereof.
  • Polypeptides of the invention are those encoded by any of the six reading frames of sequences shown in SEQ TABLES 1 AND 2, preferably encoded by the three frames reading in the 5' to 3' direction of the sequences as shown.
  • Native polypeptides include the proteins encoded by the sequences shown in SEQ TABLES 1 AND 2. Such native polypeptides include those encoded by allelic variants.
  • Variants including mutants, will exhibit at least 80% sequence identity to those native polypeptides of SEQ TABLES 1
  • sequence identity is used for polypeptides as defined above for polynucleotides. More preferably, the variants will exhibit at least 85% sequence identity; even more preferably, at least 90% sequence identity; more preferably at least 95%, 96%, 97%, 98%, or 99% sequence identity. "Fragments" of polypeptide or "portions" of polypeptides will exhibit similar degrees of identity to the relevant portions of the native polypeptide. Fusions will exhibit similar degrees of identity in that portion of the fusion represented by the variant of the native peptide.
  • variants will exhibit at least one of the functional properties of the native protein.
  • properties include, without limitation, protein interaction, DNA interaction, biological activity, immunological activity, receptor binding, signal transduction, transcription activity, growth factor activity, secondary structure, three-dimensional structure, etc.
  • the variants preferably exhibit at least 60% of the activity of the native protein; more preferably at least 70%, even more preferably at least 80%, 85%, 90% or 95% of at least one activity of the native protein.
  • a type of mutant of the native polypeptides comprises amino acid substitutions.
  • Constant substitutions are preferred to maintain the function or activity of the polypeptide. Such substitutions include conservation of charge, polarity, hydrophobicity, size, etc.
  • one or more amino acid residues within the sequence can be substituted with another amino acid of similar polarity that acts as a functional equivalent, for example providing a hydrogen bond in an enzymatic catalysis.
  • Substitutes for an amino acid within an exemplified sequence are preferably made among the members of the class to which the amino acid belongs.
  • the nonpolar (hydrophobic) amino acids include alanine, leucine, isoleucine, valine, proline, phenylalanine, tryptophan and methionine.
  • the polar neutral amino acids include glycine, serine, threonine, cysteine, tyrosine, asparagine, and glutamine.
  • the positively charged (basic) amino acids include arginine, lysine and histidine.
  • the negatively charged (acidic) amino acids include aspartic acid and glutamic acid.
  • a polypeptide of the invention may have additional individual amino acids or amino acid sequences inserted into the polypeptide in the middle thereof and/or at the N-terminal and/or C-terminal ends thereof. Likewise, some of the- amino acids or amino acid sequences may be deleted from the polypeptide.
  • Isolated polypeptides can be utilized to produce antibodies.
  • Polypeptides of the invention can generally be used, for example, as antigens for raising antibodies by known techniques.
  • the resulting antibodies are useful as reagents for determining the distribution of the antigen protein within the tissues of a plant or within a cell of a plant.
  • the antibodies are also useful for examining the expression level of proteins in various tissues, for example in a wild-type plant or following genetic manipulation of a plant, by methods such as Western blotting.
  • Antibodies of the present invention may be prepared by conventional methods.
  • the polypeptides of the invention are first used to immunize a suitable animal, such as a mouse, rat, rabbit, or goat. Rabbits and goats are preferred for the preparation of polyclonal sera due to the volume of serum obtainable, and the availability of labeled anti-rabbit and anti-goat antibodies as detection reagents.
  • Immunization is generally performed by mixing or emulsifying the protein in saline, preferably in an adjuvant such as Freund' s complete adjuvant, and injecting the mixture or emulsion parenterally (generally subcutaneously or intramuscularly).
  • Immunization is generally boosted 2-6 weeks later with one or more injections of the protein in saline, preferably using Freund' s incomplete adjuvant.
  • Polyclonal antisera is obtained by bleeding the immunized animal into a glass or plastic container, incubating the blood at 25°C for one hour, followed by incubating the blood at 4°C for 2-18 hours.
  • the serum is recovered by centrifugation (e.g., l,000xg for 10 minutes). About 20-50 ml per bleed may be obtained from rabbits.
  • Monoclonal antibodies are prepared using the method of Kohler and Milstein, Nature 256: 495 (1975), or modification thereof.
  • a mouse or rat is immunized as described above.
  • the spleen (and optinally several large lymph nodes) is removed and dissociated into single cells.
  • the spleen cells can be screened (after removal of nonspecifically adherent cells) by applying a cell suspension to a plate, or well, coated with the protein antigen.
  • B-cells expressing membrane-bound immunoglobulin specific for the antigen bind to the plate, and are not rinsed away with the rest of the suspension.
  • Resulting B-cells, or all dissociated spleen cells are then induced to fuse with myeloma cells to form hybridomas, and are cultured in a selective medium (e.g., hypoxanthine, aminopterin, thymidine medium, "HAT").
  • the resulting hybridomas are plated by limiting dilution, and are assayed for the production of antibodies which bind specifically to the immunizing antigen (and which do not bind to unrelated antigens) .
  • the selected Mab-secreting hybridomas are then cultured either in vi tro ( e . g. , in tissue culture bottles or hollow fiber reactors), or in vivo (as ascites in mice) .
  • the antibodies may be labeled using conventional techniques. Suitable labels include fluorophores, chromophores, radioactive atoms (particularly 32 P and 125 I) , electron-dense reagents, enzymes, and ligands having specific binding partners. Enzymes are typically detected by ther activity. For example, horseradish peroxidase is usually detected by its ability to convert 3, 3' , 5, 5' -tetramethylbenzidine (TNB) to a blue pigment, quantifiable with a spectrophotometer .
  • TAB 3, 3' , 5, 5' -tetramethylbenzidine
  • Specific binding partner refers to a protein capable of binding a ligand molcule with high specificity, as for example in the case of an antigen and a monoclonal antibody specific therefor.
  • Other specific binding partners include biotin and avidin or streptavidin, IgG and protein A, and the numerous receptor- ligand couples known in the art. It should be understood that the above description is not meant to categorize the various labels into distinct modes. For example, 125 I may serve as a radioactive label or as an electron-dense reagent. HRP may serve as an enzyme or as an antigen for a Mab. Further one may combine various labels for desired effect.
  • Mabs and avidin also require labels in the practice of this invention: thus, one might label a Mab with biotin, and detect its presence with avidin labeled with 125 I, or with an anti- biotin Mab labeled with HRP.
  • a Mab with biotin detects its presence with avidin labeled with 125 I, or with an anti- biotin Mab labeled with HRP.
  • soybean trypsin inhibitor (Kunitz) family is one of the numerous families of proteinase inhibitors. It comprises plant proteins which have inhibitory activity against serine proteinases from the trypsin and subtilisin families, thiol proteinases and aspartic proteinases.
  • these peptides find in vi tro use in protein purification protocols and perhaps in therapeutic settings requiring topical application of protease inhibitors.
  • Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (ALAD) catalyzes the second step in the biosynthesis of heme, the condensation of two molecules of 5-aminolevulinate to form porphobilinogen.
  • ALAD proteins can be used as catalysts in synthesis of heme derivatives.
  • Enzymes of biosynthetic pathways generally can be used as catalysts for in vi tro synthesis of the compounds representing products of the pathway.
  • Polypeptides encoded by SDFs of the invention can be engineered to provide purification reagents to identify and purify additional polypeptides that bind to them. This allows one to identify proteins that function as multimers or elucidate signal transduction or metabolic pathways.
  • polypeptide in the case of DNA binding proteins, can be used in a similar manner to identify the DNA determinants of specific binding (S. Pierrou et al., Anal . Biochem . 229:99 (1995), S. Chusacultanachai et al., J. Biol . Chem . 274:23591 (1999), Q.
  • mutants, fragments, or fusions of the polypeptides encoded by the maximum length seuqence can exhibit at least one of the activities of the identified domains and/or related polypeptides described in Sections (C) and (D) of REF TABLES 1 and 2 corresponding to the MLS of interest .
  • a type of mutant of the native polypeptides comprises amino acid substitutions.
  • Constant substitutions described above (see II.), are preferred to maintain the function or activity of the polypeptide. polypeptide. Such substitutions include conservation of charge, polarity, hydrophobicity, size, etc.
  • one or more amino acid residues within the sequence can be substituted with another amino acid of similar polarity that acts as a functional equivalent, for example providing a hydrogen bond in an enzymatic catalysis.
  • Substitutes for an amino acid within an exemplified sequence are preferably made among the members of the class to which the amino acid belongs.
  • the nonpolar (hydrophobic) amino acids include alanine, leucine, isoleucine, valine, proline, phenylalanine, tryptophan and methionine.
  • the polar neutral amino acids include glycine, serine, threonine, cysteine, tyrosine, asparagine, and glutamine.
  • the positively charged (basic) amino acids include arginine, lysine and histidine.
  • the negatively charged (acidic) amino acids include aspartic acid and glutamic acid.
  • a polypeptide of the invention may have additional individual amino acids or amino acid sequences inserted into the polypeptide in the middle thereof and/or at the N-terminal and/or C-terminal ends thereof. Likewise, some of the amino acids or amino acid sequences may be deleted from the polypeptide. Amino acid substitutions may also be made in the sequences; conservative substitutions being preferred.
  • mutants are those that comprise (1) the domain of a MLS encoded polypeptide and/or
  • Another class of mutants includes those that comprise a MLS encoded polypeptide sequence that is changed in the domain or conserved residues by a conservative substitution.
  • mutants include those that lack one of the in vi tro activities, or structural features of the MLS encoded polypeptides.
  • One example is dominant negative mutants.
  • Such a mutant may comprise an MLS encoded polypeptide sequence with non-conservative changes in a particular domain or group of conserved residues.
  • Fragments of particular interest are those that comprise a domain identified for a polypeptide encoded by an MLS of the instant invention and mutants thereof. Also, fragments that comprise at least one region of residues conserved between an MLS encoded polypeptide and its related polypeptides are of great interest. Fragments are sometimes useful as dominant negative mutations.
  • FUSIONS Of interest are chimeras comprising (1) a fragment of the MLS encoded polypeptide or mutants thereof of interest and (2) a fragment of a polypeptide comprising the same domain.
  • the present invention also encompasses fusions of MLS encoded polypeptides, mutants, or fragments thereof fused with related proteins or fragments thereof. DEFINITION OF DOMAINS
  • the polypeptides of the invention may possess identifying domains as shown in REF TABLES 1 and 2. Domains are fingerprints or signatures that can be used to characterize protein families and/or motifs. Such fingerprints or signatures can comprise conserved (1) primary sequence, (2) secondary structure, and/or (3) three- dimensional conformation. Generally, each domain has been associated with either a family of proteins or a motif. Typically, these families and/or motifs have been correlated with specific in-vi tro and/or in-vivo activities. A domain can be any length, including the entirety of the sequence of a protein. Detailed descriptions of the domains, associated families and motifs, and correlated activities of the polypeptides of the instant invention are described below. Usually, the polypeptides with designated domain (s) can exhibit at least one activity that is exhibited by any polypeptide that comprises the same domain (s).
  • domains within the MLS encoded polypeptides are indicated by the reference REF TABLES 1 and 2.
  • the domains within the MLS encoded polypeptide can be defined by the region that exhibits at least 70% sequence identity with the consensus sequences listed in the detailed description below of each of the domains. The majority of the protein domain descriptions given below are obtained from Prosite,
  • AAA 220 amino acids that contains anATP-binding site.
  • This family is now called AAA, for 'A'TPases 'A'ssociated with diverse cellular ' A 1 ctivities .
  • the proteins that belong to this family either contain one or two AAA domains. Proteins containing two AAA domains:
  • NSF N-ethylmaleimide-sensitive fusion protein
  • SEC18 the fungal homolog
  • - Mammalian transitional endoplasmic reticulum ATPase (previously known as p97 or VCP) which is involved in the transfer of membranes from the endoplasmic reticulum to the golgi apparatus.
  • This protein forms a ring-shaped homooligomer composed of six subunits.
  • the yeast homolog is CDC48 and it may play a role in spindle pole proliferation.
  • FtsH is an ATP-dependent zinc metallopeptidase that seems to degrade the heat-shock sigma-32 factor. It is an integral membrane protein with a large cytoplasmic C-terminal domain that contain both the AAA and the protease domains .
  • YMEl a protein important for maintaining the integrity of the mitochondrial compartment. YMEl is also a zinc-dependent protease.
  • Yeast protein AFG3 (or YTA10) . This protein also seems to contain a AAA domain followed by a zinc-dependent protease domain.
  • Subunits from the regulatory complex of the 26S proteasome [6] which is involved in the ATP-dependent degradation of ubiquitinated proteins a) Mammalian subunit 4 and homologs in other higher eukaryotes, in yeast (gene YTA5) and fission yeast (gene mts2) . b) Mammalian subunit 6 (TBP7) and homologs in other higher eukaryotes and in yeast (gene YTA2) . c) Mammalian subunit 7 (MSS1) and homologs in other higher eukaryotes and in yeast (gene CIM5 or YTA3) .
  • Mammalian subunit 8 P45
  • homologs in other higher eukaryotes and in yeast SUV1 or CIM3 or TBY1
  • fission yeast gene letl
  • Other probable subunits such as human TBP1 which seems to influences HIV gene expression by interacting with the virus tat transactivator protein and yeast YTA1 and YTA6.
  • Yeast protein BCS1 a mitochondrial protein essential for the expression of the Rieske iron-sulfur protein.
  • - Yeast protein MSP1 a protein involved in intramitochondrial sorting of proteins.
  • - Mouse protein SKD1 and its fission yeast homolog SpAC2G11.06
  • Caenorhabditis elegans meiotic spindle formation protein mei-1 Yeast protein SAP1. - Yeast protein YTA7.
  • AAA domains in these proteins act as ATP-dependent protein clamps [5] .
  • ATP-dependent protein clamps [5] .
  • ATP-binding 'A' and 'B' motifs which are located in the N-terminal half of this domain, there is a highly conserved region located in the central part of the domain which was used to develop a signature pattern.
  • Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [1,2] into subfamilies.
  • class-IV currently consists of the following enzymes: Branched-chain amino-acid aminotransferase (EC 2.6.1.42) (transaminase B) , a bacterial (gene ilvE) and eukaryotic enzyme which catalyzes the reversible transfer of an amino group from 4-methyl-2- oxopentanoate to glutamate, to form leucine and 2- oxoglutarate.
  • D-alanine aminotransferase (EC 2.6.1.21) .
  • a bacterial enzyme which catalyzes the transfer of the amino group from D-alanine (and other D-amino acids) to 2- oxoglutarate, to form pyruvate and D-aspartate.
  • ADC 4-amino-4-deoxychorismate
  • gene pabC gene pabC
  • the above enzymes are proteins of about 270 to 415 amino-acid residues that share a few regions of sequence similarity. Surprisingly, the best-conserved region does not include the lysine residue to which the pyridoxal- phosphategroup is known to be attached, in ilvE. The region that has been selected as a signature pattern is located some
  • the bacterial mutT protein is involved in the GO system [1] responsible for removing an oxidatively damaged form of guanine (8-hydroxyguanine or7 , 8-dihydro-8-oxoguanine) from DNA and the nucleotide pool.
  • 8-oxo-dGTP is inserted opposite to dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions .
  • MutT specifically degrades 8-oxo-dGTP to the monophosphate with the concomitant release of pyrophosphate.
  • MutT is a small protein of about 12 to 15 Kd. It has been shown [2,3] that a region of about 40 amino acid residues, which is found in the
  • N-terminal part of mutT can also be found in a variety of other prokaryotic, viral, and eukaryotic proteins. These proteins are:
  • Streptomyces pneumoniae mutX Streptomyces pneumoniae mutX.
  • Bartonella bacilliformis invasion protein A (gene invA) .
  • Escherichia coli dATP pyrophosphohydrolase Escherichia coli dATP pyrophosphohydrolase .
  • Protein D250 from African swine fever viruses Protein D250 from African swine fever viruses.
  • Proteins D9 and D10 from a variety of poxviruses are proteins D9 and D10 from a variety of poxviruses.
  • Mammalian diadenosine 5 ' , 5 ' ' ' -Pi, P4-tetraphosphate asymmetrical hydrolase (Ap4Aase) (EC 3.6.1.17) [5], which cleaves A-5'-PPPP-5'A to yield AMP and ATP.
  • Yeast protein YSA1 Yeast protein YSA1.
  • Escherichia coli hypothetical protein yfaO Escherichia coli hypothetical protein yfaO.
  • Escherichia coli hypothetical protein ygdU and HI0901 the corresponding Haemophilus influenzae protein.
  • Escherichia coli hypothetical protein yjaD and HI0432 the corresponding Haemophilus influenzae protein.
  • Escherichia coli hypothetical protein yrfE Escherichia coli hypothetical protein yrfE.
  • Bacillus subtilis hypothetical protein yqkG Bacillus subtilis hypothetical protein yqkG.
  • the conserved domain could be involved in the active center of a family of pyrophosphate- releasing NTPases. As a signature pattern the core region of the domain was selected; it contains four conserved glutamate residues .
  • Type 1 cystatins (or stefins) , molecules of about 100 amino acid residues with neither disulfide bonds nor carbohydrate groups.
  • Type 2 cystatins molecules of about 115 amino acid residues which contain one or two disulfide loops near their C-terminus.
  • Kininogens which are multifunctional plasma glycoproteins .
  • bradykinins They are the precursor of the active peptide bradykinin and play a role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII.
  • kininogens are made of three contiguous type-2 cystatin domains, followed by an additional domain (of variable length) which contains the sequence of bradykinin. The first of the three cystatin domains seems to have lost its inhibitory activity.
  • a number of proteins are produced by plants that experience water-stress. Water-stress takes place when the water available to a plant falls below a critical level. The plant hormone abscisic acid (ABA) appears to modulate the response of plant to water-stress. Proteins that are expressed during water-stress are called dehydrins [1,2] or LEA group 2 proteins [3] . The proteins that belong to this family are listed below. - Arabidopsis thaliana XERO 1, XERO 2 (LTI30), RAB18,
  • Dehydrins share a number of structural features. One of the most notable features is the presence, in their central region, of a continuous run of five to nine serines followed by a cluster of charged residues. Such a region has been found in all known dehydrins so far with the exception of pea dehydrins.
  • a second conserved feature is the presence of two copies of alysine-rich octapeptide; the first copy is located just after the cluster of charged residues that follows the poly-serine region and the second copy is found at the C-terminal extremity. Signature patterns for both regions were derived.
  • Consensus pattern S (5) - [DE] -x- [DE] -G-x (1, 2) -G-x (0, 1) - [KR] (4 Consensus pattern: [KR] - [LIM] -K- [DE] -K- [LIM] -P-G-
  • This Pfam covers the Formate dehydrogenase, D-glycerate dehydrogenase and D-lactate dehydrogenase families in SCOP.
  • a number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown [1,2,3,4] to be functionally and structurally related. These enzymes are listed below.
  • D-lactate dehydrogenase (EC 1.1.1.28), a bacterial enzyme which catalyzes the reduction of D-lactate to pyruvate.
  • 3-phosphoglycerate dehydrogenase (EC 1.1.1.95), a bacterial enzyme that catalyzes the oxidation of D-3- phosphoglycerate to 3-phosphohydroxypyruvate .
  • This reaction is the first committed step in the 1 phosphorylated ' pathway of serine biosynthesis.
  • Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-) (gene pdxB) , a bacterial enzyme involved in the biosynthesis of pyridoxine (vitamin B6) .
  • D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-) (D- hicDH) , a bacterial enzyme that catalyzes the reversible and stereospecific interconversion between 2-ketocarboxylic acids and D-2-hydroxy-carboxylic acids .
  • Formate dehydrogenase (EC 1.2.1.2) (FDH) from the bacteria Pseudomonas sp. 101 and various fungi [5] .
  • Escherichia coli hypothetical protein ycdW (EC 1.2.1.2)
  • Escherichia coli hypothetical protein yiaE Escherichia coli hypothetical protein yiaE.
  • Haemophilus influenzae hypothetical protein HI1556 Haemophilus influenzae hypothetical protein HI1556.
  • Yeast hypothetical protein YIL074w All these enzymes have similar enzymatic activities and are structurally related. Three of the most conserved regions of these proteins have been selected to develop patterns. The first pattern is based on a glycine-rich region located in the central section of these enzymes; this region probably corresponds to the NAD-binding domain. The two other patterns contain a number of conserved charged residues, some of which may play a role in the catalytic mechanism.
  • the prokaryotic heat shock protein dnaJ interacts with the chaperone hsp70-like dnaK protein [1].
  • the dnaJ protein consists of an N- terminal conserved domain (called 'J' domain) of about 70 amino acids, a glycine-rich region ('G' domain') of about 30 residues, a central domain containing four repeats of a CXXCXGXG motif ('CRR' domain) and a C-terminal region of 120 to 170 residues.
  • 'J' domain conserved domain
  • 'G' domain' glycine-rich region
  • 'CRR' domain central domain containing four repeats of a CXXCXGXG motif
  • C-terminal region 120 to 170 residues.
  • Yeast protein MDJ1 involved in mitochondrial biogenesis and protein folding.
  • Yeast protein SCJ1 involved in protein sorting.
  • Yeast protein XDJl involved in protein sorting.
  • Plants dnaJ homologs (from leek and cucumber) .
  • Yeast hypothetical protein YNL077w b) Proteins containing a 'J' domain without a 'CRR' domain: Rhizobium fredii nolC, a protein involved in cultivar- specific nodulation of soybean.
  • Escherichia coli cbpA [3] a protein that binds curved
  • DNA - Yeast protein SEC63/NPL1, important for protein assembly into the endoplasmic reticulum and the nucleus .
  • Yeast protein SIS1 required for nuclear migration during mitosis.
  • RESA Plasmodium falciparum ring-infected erythrocyte surface antigen
  • Human HSJ1 a neuronal protein.
  • csp Drosophila cysteine-string protein
  • a signature pattern for the 'J' domain was developed, based on conserved positions in the C-terminal half of this domain.
  • a pattern for the 'CRR' domain based on the first two copies of that motif was also developed.
  • a profile for the 'J' domain was also developed.
  • Gamma-thionins from wheat endosperm gamma- purothionins
  • barley gamma- hordothionins
  • FST flower-specific thionin
  • AFP Antifungal proteins from the seeds of Brassicaceae species such as radish, mustard, turnip and Arabidopsis thaliana [3] .
  • SF18 is a protein that contains a gamma-thionin domain at its N-terminus and a proline-rich C- terminal domain.
  • Vicia faba antibacterial peptides fabatin-1 and -2 In their mature form, these proteins generally consist of about 45 to 50amino-acid residues. As shown in the following schematic representation, these peptides contain eight conserved cysteines involved in disulfide bonds.
  • This family is structurally different from the alpha/ beta hydrolase family (abhydrolase) .
  • This family includes L- 2-haloacid dehalogenase, epoxide hydrolases and phosphatases.
  • the structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment, between residues 16 and 96 of Swiss : P24069. The rest of the fold is composed of the core alpha/beta domain.
  • Helix-turn-helix This large family of DNA binding helix-turn helix proteins includes Cro Swiss: P03036 and CI Swiss: P03034.
  • Cytochrome b5 is a membrane-bound hemo protein which acts as an electron carrier for several membrane-bound oxygenases [1]. There are two homologous forms of b5, one found in microsomes and one found in the outer membrane of mitochondria. Two conserved histidine residues serve as axial ligands for the heme group.
  • the structure of a number of oxidoreductases consists of the juxtaposition of a heme- binding domain homologous to that of b5 and either a flavodehydrogenase or a molybdopterin domain. These enzymes are:
  • Lactate dehydrogenase (EC 1.1.2.3) [2], an enzyme that consists of a flavodehydrogenase domain and a heme- binding domain called cytochrome b2.
  • Nitrate reductase (EC 1.6.6.1) , a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria [3,4].
  • Consists of a molybdopterin domain see ⁇ PDOC00484>
  • cytochrome b557 a heme-binding domain called cytochrome b557
  • cytochrome reductase domain Consists of a molybdopterin domain (see ⁇ PDOC00484>) , a heme-binding domain called cytochrome b557, as well as a cytochrome reductase domain.
  • Fission yeast hypothetical protein SpAClF12.10c Yeast hypothetical protein YMR073c. Yeast hypothetical protein YMR272c.
  • a segment was used which includes the first of the two histidine heme ligands, as a signature pattern for the heme- binding domain of cytochrome b5 family.
  • KH domain KH motifs probably bind RNA directly. Auto antibodies to
  • MAPEG family (aka: FLAP/GST2/LTC4S family signature)
  • mammalian proteins are evolutionary related [1] : - Leukotriene C4 synthase (EC 2.5.1.37) (gene LTC4S) , an enzyme that catalyzes the production of LTC4 from LTA4.
  • Microsomal glutathione S-transferase II (EC 2.5.1.18)
  • GST-II gene GST2
  • 5-lipoxygenase activating protein (gene FLAP) , a protein that seems to be required for the activation of 5-lipoxygenase.
  • proteins of 150 to 160 residues that contain three transmembrane segments that contain three transmembrane segments.
  • a conserved region between the first and second transmembrane domains was selected.
  • Bet v I the major pollen allergen from white birch.
  • Bet v I is the main cause of type I allergic reactions in Europe, North America and USSR.
  • Aln g I the major pollen allergen from alder.
  • Api G I the major allergen from celery.
  • Car b I the major pollen allergen from hornbeam.
  • Mai d I the major pollen allergen from apple.
  • Pea disease resistance response proteins pI49, pI176 and DRRG49-C Pea disease resistance response proteins pI49, pI176 and DRRG49-C.
  • Soybean stress-induced protein SAM22 Soybean stress-induced protein SAM22.
  • proteins are thought to be intracellularly located. They contain from 155 to 160 amino acid residues. As a signature pattern, a conserved region located in the third quarter of these proteins has been selected
  • Photosystem I psaG / psaK (PSI PSAK) proteins signature Photosystem I (PSI) [1] is an integral membrane protein complex that uses light energy to mediate electron transfer from plastocyanin to ferredoxin. It is found in the chloroplasts of plants and cyanobacteria . PSI is composed of at least 14 different subunits, two of which PSI-G (gene psaG) and PSI-K (gene psaK) are small hydrophobic proteins of about 7 to 9 Kd and evolutionary related [2] . Both seem to contain two transmembrane regions. Cyanobacteria seem to encode only for PSI-K.
  • the best-conserved region was selected which seems to correspond to the second transmembrane region.
  • Plant cells contain proteins, called lipid transfer proteins (LTP) [1,2,3], which are able to facilitate the transfer of phospholipids and other lipidsacross membranes. These proteins, whose subcellular location is not yet known, could play a major role in membrane biogenesis by conveying phospholipids such as waxes or cutin from their site of biosynthesis to membranes unable to form these lipids.
  • Plant LTP's are proteins of about 9 Kd (90 amino acids) which contain eight conserved cysteine residues all involved in disulfide bridges, as shown in the following schematic representation.
  • 'C conserved cysteine involved in a disulfide bond.
  • '*' position of the pattern.
  • Ribosomal protein S7e signature A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities [1]. One of these families consists of:
  • Ribosomal protein L34 is one of the proteins from the large subunit of the prokaryotic ribosome. It is a small basic protein of 44 to 51 amino-acid residues [1] . L34 belongs to a family of ribosomal proteins which, on the basis of sequence similarities, groups: - Eubacterial L34. - Red algal chloroplast L34. - Cyanelle L34. A conserved region that corresponds to the N-terminal half of L34 has been selected as a signature pattern. -Consensus pattern: K- [RG] -T- [FYWL] - [EQS] -x (5) - [KRHS] -x (4 , 5) - G-F-x(2)-R
  • Ribosomal protein L6 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L6 is known to bind directly to the 23S rRNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3,4], groups: -
  • Algal chloroplast L6 Algal chloroplast L6. - Cyanelle L6.
  • Marchantia polymorpha mitochondrial L6 Yeast mitochondrial YmL ⁇ (gene MRPL6) . Mammalian L9. - Drosophila L9.
  • Ribosomal protein S14 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S14 is known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of 16S rRNA at the A site. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:
  • Archaebacterial Methanococcus vannielii S14 Plant mitochondrial S14.
  • Yeast mitochondrial MRP2. Mammalian S29.
  • S14 is a protein of 53 to 115 amino-acid residues. Our signature pattern is based on the few conserved positions located in the center of these proteins.
  • Ribosomal protein S16 signature Ribosomal protein S16 is one of the proteins from the small ribosomal subunit. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: Eubacterial S16. Algal and plant chloroplast S16.
  • Neurospora crassa mitochondrial S24 (cyt-21) .
  • S16 is a protein of about 100 amino-acid residues. A conserved region located in the N-terminal extremity of these proteins has been selected as a signature pattern.
  • Ribosomal protein S21 is one of the proteins from the small ribosomal subunit. So far S21 has only been found in eubacteria. It is a protein of 55 to 70 amino-acid residues. A conserved region in the N-terminal section of the protein has been selected as a signature pattern.
  • heterologous sequences are those that are not operatively linked or are not contiguous to each other in nature.
  • a promoter from corn is considered heterologous to an Arabidopsis coding region sequence.
  • a promoter from a gene encoding a growth factor from corn is considered heterologous to a sequence encoding the corn receptor for the growth factor.
  • Regulatory element sequences such as UTRs or 3' end termination sequences that do not originate in nature from the same gene as the coding sequence originates from, are considered heterologous to said coding sequence.
  • chimeric polynucleotides are of particular interest for modulating gene expression in a host cell upon transformation of said cell with said chimeric polynucleotide.
  • DNA molecules are useful for transforming the genome of a host cell or an organism regenerated from said host cell.
  • Such polynucleotides are "exogenous to" the genome of an individual host cell or the organism regenerated fro ⁇ m said host cell, such as a plant cell, respectively for a plant, when initially or subsequently introduced into said host cell or organism, by any means other than by a sexual cross. Examples of means by which this can be accomplished are described below, and include Agrobacterium- mediated transformation (of dicots - e.g. Salomon et al . EMBO
  • Transgenic plants which arise from a sexual cross with another parent line or by selfing are "descendants or the progeny" of a R_ plant and are generally called F n plants or S n plants, respectively, n meaning the number of generations.
  • the SDFs prepared as described herein can be used to prepare expression cassettes useful in a number of techniques for suppressing or enhancing expression.
  • Expression cassettes of the invention can be used to suppress expression of endogenous genes which comprise the SDF sequence. Inhibiting expression can be useful, for instance, to tailor the ripening characteristics of a fruit (Oeller et al., Science 254:437 (1991)) or to influence seed size__(WO98/07842) or or to provoke cell ablation (Mariani et al., Nature 357: 384-387 (1992).
  • An expression cassette as described above can be transformed into host cell or plant to produce an antisense strand of RNA.
  • antisense RNA inhibits gene expression by preventing the accumulation of mRNA which encodes the enzyme of interest, see, e.g., Sheehy et al., Proc . Na t . Acad. Sci . USA, 85:8805 (1988), and Hiatt et al., U.S. Patent No. 4,801,340.
  • Ribozymes Similarly, ribozyme constructs can be transformed into a plant to cleave mRNA and down-regulate translation.
  • Another method of suppression is by introducing an exogenous copy of the gene to be suppressed.
  • Introduction of expression cassettes in which a nucleic acid is configured in the sense orientation with respect to the promoter has been shown to be an effective means by which to block the transcription of target genes. A detailed description of this method is described above.
  • Such screening can be performed using probes and/or primers described above based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto.
  • the screening can also be performed by selecting clones or Ri plants having a desired phenotype.
  • triple helices can be formed using oligonucleotides based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto.
  • the oligonucleotide can be delivered to the host cell can bind to the promoter in the genome to form a triple helix and prevent transcription.
  • a vector capable of producing the oligonucleotide can be inserted into the host cell to deliver the oligonucleotide.
  • A.6 Expression of Mutants
  • Dominant negative mutations produce a mutant polypeptide which is capable of competing with the native polypeptide, but which does not produce the native result. Consequently, over expression of these mutations can titrate out an undesired activity of the native protein.
  • the inactive dominant-negative mutant may bind to the same receptor as the native protein, preventing the native protein from activating a signal transduction pathway.
  • the dominant- negative mutant can be an inactive enzyme still capable of binding to the same substrate as the native protein.
  • Dominant-negative mutants also can act upon the native protein itself to prevent activity.
  • the native protein may be active only as a homo-multimer or as one subunit of a hetero-multimer . Incorporation of an inactive subunit into the multimer with native subunit (s) can inhibit activity.
  • gene function can be modulated by insertion of an expression construct encoding a dominant-negative mutant into a host cell of interest.
  • III.B Enhanced Expression
  • Enhanced expression of a gene of interest in a host cell can be accomplished by either (1) insertion of an exogenous gene; or (2) promoter modulation.
  • Insertion of an expression construct encoding an exogenous gene can boost the number of gene copies expressed in a host cell.
  • Such expression constructs can comprise genes that either encode the native protein that is of interest or that encode a variant that exhibits enhanced activity as compared to the native protein.
  • genes encoding proteins of interest can be constructed from the sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto.
  • Such an exogenous gene can include either a constitutive promoter permitting expression in any cell in a host organism or a promoter that directs expression only in particular cells or times during a host cell life cycle or in response to environmental stimuli.
  • a constitutive promoter permitting expression in any cell in a host organism
  • a promoter that directs expression only in particular cells or times during a host cell life cycle or in response to environmental stimuli.
  • promoters require binding of a regulatory protein to be activated.
  • Other promoters may need a protein that signals a promoter binding protein to expose a polymerase binding site. In either case, over-expression of such proteins can be used to enhance expression of a gene of interest by increasing the activation time of the promoter.
  • Such regulatory proteins are encoded by some of the sequences in SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequences thereto.
  • Coding sequences for these proteins can be constructed as described above.
  • the useful enhancer elements can be portions of one or more of the SDFs of SEQ TABLES 1 AND 2.
  • recombinant DNA vectors which comprise said SDFs and are suitable for transformation of cells, such as plant cells, are usually prepared.
  • the vector backbone can be any of those typical in the art such as plasmids, viruses, artificial chromosomes, BACs, YACs and PACs and vectors of the sort described by **.
  • a vector will comprise the exogenous gene, which in its turn comprises an SDF of the present invention to be introduced into the genome of a host cell, and which gene may be an antisense construct, a ribozyme construct, or a structural coding sequence with any desired transcriptional and/or translational regulatory sequences, such as promoters and 3' end termination sequences.
  • Vectors of the invention can also include origins of replication, markers, homologous sequences, introns, etc.
  • a DNA sequence coding for the desired polypeptide will preferably be combined with transcriptional and translational initiation regulatory sequences which will direct the transcription of the sequence from the gene in the intended tissues of the transformed plant.
  • a plant promoter fragment may be employed that will direct expression of the gene in all tissues of a regenerated plant. Such promoters are referred to herein as "constitutive" promoters and are active under most environmental conditions and states of development or cell differentiation.
  • constitutive promoters examples include the cauliflower mosaic virus (CaMV) 35S transcription initiation region, the 1' or 2' promoter derived from T-DNA of Agrobacterium tumefaciens , and other transcription initiation regions from various plant genes known to those of skill.
  • the plant promoter may direct expression of an SDF of the invention in a specific tissue (tissue-specific promoters) or may be otherwise under more precise environmental control (inducible promoters) .
  • tissue-specific promoters under developmental control include promoters that initiate transcription only in certain tissues, such as root, ovule, fruit, seeds, or flowers. The promoter from a LEC1 gene, described in copending application U.S. Ser. No.
  • 09/103,4708 is particularly useful for directing gene expression so that a desired gene product is located in embryos or seeds.
  • suitable promoters include those from genes encoding storage proteins or the lipid body membrane protein, oleosin. A few root-specific promoters are noted above. Examples of environmental conditions that may affect transcription by inducible promoters include anaerobic conditions, elevated temperature, or the presence of light.
  • polyadenylation region at the 3 ' -end of the coding region should be included.
  • the polyadenylation region can be derived from the natural gene, from a variety of other plant genes, or from T-DNA.
  • the vector comprising the sequences (e. g. , promoters or coding regions) from genes of the invention will typically comprise a marker gene that confers a selectable phenotype on plant cells.
  • the marker may encode biocide resistance, particularly antibiotic resistance, such as resistance to kanamycin, G418, bleomycin, hygromycin, or herbicide resistance, such as resistance to chlorosulfuron or phosphinotricin.
  • sequence in the transformation vector and to be introduced into the genome of the host cell does not need to be absolutely identical to an SDF of the present invention. Also, it is not necessary for it to be full length, relative to either the primary transcription product or fully processed mRNA. Use of sequences shorter than full-length may be preferred to avoid concurrent production of some plants that are overexpressors. Furthermore, the introduced sequence need not have the same intron or exon pattern as a native gene. Also, heterologous non-coding segments can be incorporated into the coding sequence without changing the desired amino acid sequence of the polypeptide to be produced.
  • introducing an exogenous SDF from the same species or an orthologous SDF from another species can modulate the expression of a native gene corresponding to that SDF of interest.
  • Such an SDF construct can be under the control of either a constitutive promoter (e . g. , the promoter of the 35S gene of the cauliflower mosaic virus or the promotor of the gene encoding the cowpea trypsin inhibitor) or a highly regulated inducible promoter (e.g., a copper inducible promoter) .
  • the promoter of interest can initially be either endogenous or heterologous to the species in question. When re-introduced into the genome of said species, such promoter becomes "exogenous" to said species.
  • the promoter-SDF construct can be made using standard recombinant DNA techniques (Sambrook et al. 1989) and can be introduced to the species of interest by ⁇ grojacterium-mediated transformation or by other means of transformation (e.g., particle gun bombardment) as referenced above.
  • Over- expression of an SDF transgene can lead to co-suppression of the homologous gene thereby creating some alterations in the phenotypes of the transformed species as demonstrated by similar analysis of the chalcone synthase gene (Napoli et al., Plan t Cell 2:279 (1990) and van der Krol et al., Plant Cell 2:291 (1990)).
  • an SDF is found to encode a protein with desirable characteristics, its over-expression can be controlled so that its accumulation can be manipulated in an organ- or tissue-specific manner utilizing a promoter having such specificity.
  • a promoter of an SDF or an SDF that includes a promoter
  • tissue-specific or developmentally regulated such a promoter can be utilized to drive the expression of a specific gene of interest (e.g., seed storage protein or root-specific protein) .
  • a specific gene of interest e.g., seed storage protein or root-specific protein
  • the protein encoded by an introduced exogenous or orthologous SDF may be targeted (1) to a particular organelle, (2) to interact with a particular molecule or (3) for secretion outside of the cell harboring the introduced SDF. This will be accomplished using a signal peptide.
  • Signal peptides direct protein targeting, are involved in ligand-receptor interactions and act in cell to cell communication. Many proteins, especially soluble proteins, contain a signal peptide that targets the protein to one of several different intracellular compartments. In plants, these compartments include, but are not limited to, the endoplasmic reticulum (ER) , mitochondria, plastids (such as chloroplasts) , the vacuole, the Golgi apparatus, protein storage vessicles (PSV) and, in general, membranes .
  • ER endoplasmic reticulum
  • mitochondria mitochondria
  • plastids such as chloroplasts
  • the vacuole the Golgi apparatus
  • PSV protein storage vessicles
  • signal peptide sequences are conserved, such as the Asn-Pro- Ile-Arg amino acid motif found in the N-terminal propeptide signal that targets proteins to the vacuole (Marty (1999) The Plant Cell 11: 587-599).
  • Other signal peptides do not have a consensus sequence per se, but are largely composed of hydrophobic amino acids, such as those signal peptides targeting proteins to the ER (Vitale and Denecke (1999) The Plant Cell 11: 615-628). Still others do not appear to contain either a consensus sequence or an identified common secondary sequence, for instance the chloroplast stromal targeting signal peptides (Keegstra and Cline (1999) The Plant Cell 11: 557-570).
  • targeting peptides are bipartite, directing proteins first to an organelle and then to a membrane within the organelle (e.g. within the thylakoid lumen of the chloroplast; see Keegstra and Cline (1999) The Plant Cell 11: 557-570).
  • a membrane within the organelle e.g. within the thylakoid lumen of the chloroplast; see Keegstra and Cline (1999) The Plant Cell 11: 557-570.
  • placement of the signal peptide is also varied. Proteins destined for the vacuole, for example, have targeting signal peptides found at the N-terminus, at the C-terminus and at a surface location in mature, folded proteins.
  • Signal peptides also serve as ligands for some receptors. Perhaps the best known example of this is the interaction of the ER targeting signal peptide with the signal recognition particle (SRP) .
  • SRP signal recognition particle
  • the SRP binds to the signal peptide, halting translation, and the resulting signal peptide
  • SRP complex then binds to docking proteins located on the surface of the ER, prompting the transfer of the protein into the ER.
  • signal proteins can be used to more tightly control the expression of introduced SDFs.
  • associating the appropriate signal sequence with a specific SDF can allow sequestering of the protein in specific organelles (plastids, as an example) , secretion outside of the cell, targeting interaction with particular receptors, etc.
  • the inclusion of signal proteins in constructs involving the SDFs of the invention increases the range of manipulation of SDF expression.
  • constructs are made with the nucleotide sequence of a known signal peptide immediately 5' to the initiation of the coding region of an SDF so that the signal peptide is translated in frame with the coding region and immediately precedes it.
  • the nucleotide sequence of the signal peptide can be isolated from characterized genes using common molecular biological techniques or can be synthesized in vitro.
  • DNA constructs of the invention may be introduced into the genome of the desired plant host by a variety of conventional techniques.
  • the DNA construct may be introduced directly into the genomic DNA of the plant cell using techniques such as electroporation and microinjection of plant cell protoplasts, or the DNA constructs can be introduced directly to plant tissue using ballistic methods, such as DNA particle bombardment.
  • the DNA constructs may be combined with suitable T-DNA flanking regions and introduced into a conventional Agrobacterium tumefaciens host vector. The virulence functions of the Agrobacterium tumefaciens host will direct the insertion of the construct and adjacent marker into the plant cell DNA when the cell is infected by the bacteria
  • Electroporation techniques are described in Fromm et al. Proc. Na tl Acad. Sci . USA 82:5824 (1985). Ballistic transformation techniques are described in Klein et al . Nature
  • Transformed plant cells which are derived by any of the above transformation techniques can be cultured to regenerate a whole plant that possesses the transformed genotype and thus the desired phenotype such as seedlessness.
  • Such regeneration techniques rely on manipulation of certain phytohormones in a tissue culture growth medium, typically relying on a biocide and/or herbicide marker which has been introduced together with the desired nucleotide sequences.
  • Plant regeneration from cultured protoplasts is described in Evans et al., Protoplasts Isola tion and Cul ture in "Handbook of Plant Cell Culture," pp. 124-176, MacMillan Publishing Company, New York, 1983; and Binding, Regenera tion of Plants, Plant Protoplasts, pp.
  • Regeneration can also be obtained from plant callus, explants, organs, or parts thereof. Such regeneration techniques are described generally in Klee et al. Ann. Rev. of Plant Phys . 38:467 (1987). Regeneration of monocots (rice) is described by Hosoyama et al. ( Biosci . Biotechnol . Biochem . 58:1500 (1994)) and by Ghosh et al. ( J. Biotechnol . 32:1 (1994)).
  • the nucleic acids of the invention can be used to confer desired traits on essentially any plant.
  • the invention has use over a broad range of plants, including species from the genera Asparagus , Atropa , Avena ,
  • One of skill will recognize that after the expression cassette is stably incorporated in transgenic plants and confirmed to be operable, it can be introduced into other plants by sexual crossing. Any of a number of standard breeding techniques can be used, depending upon the species to be crossed.
  • the SDFs of the invention can be used in Southern hybridizations as described above.
  • the following describes extraction of DNA from nuclei of plant cells, digestion of the nuclear DNA and separation by length, transfer of the separated fragments to membranes, preparation of probes for hybridization, hybridization and detection of the hybridized probe.
  • Moderate stringency hybridization conditions as defined above, are described in the present example. These conditions result in detection of hybridization between sequences having at least 70% sequence identity. As described above, the hybridization and wash conditions can be changed to reflect the desired degree of sequence identity between probe and target sequences that can be detected.
  • a probe for t-ke hybridization is produced from two PCR reactions using two primers from genomic sequence of Arabidopsis thaliana .
  • the particular template for generating the probe can be any desired template.
  • the first PCR product is assessed to validate the size of the primer to assure it is of the expected size. Then the product of the first PCR is used as a template, with the same pair of primers used in the first PCR, in a second PCR that produces a labeled product used as the probe.
  • Fragments detected by hybridization, or other bands of interest can be isolated from gels used to separate genomic DNA fragments by known methods for further purification and/or characterization.
  • IxHB per blender Be sure that you use 5-10 ml of HB buffer per gram of tissue. Blenders generate heat so be sure to keep the homogenate cold. It is necessary to put the blenders- in ice periodically.
  • the first filtration is through a 250-micron membrane; the second is through an 85-micron membrane; the third is through a 50-micron membrane; and the fourth is through a 20-micron membrane.
  • the pellet Discard the dark green supernatant.
  • the pellet will have several layers to it.
  • the nuclei are gray and soft. In the early steps, there may be a dark green and somewhat viscous layer of chloroplasts .
  • the DNA band should be visible in room light; otherwise, use a long wave UV light to locate the band.
  • yeast DNA Precipitate the DNA by adding 3 volumes of 100% ethanol. Incubate at -20 ° C for at least two hours. Yeast DNA can be purchased and made up at the necessary concentration, therefore no precipitation is necessary for yeast DNA.
  • the digested DNA samples are electrophoresed in 1% agarose gels in lx TPE buffer. Low voltage; overnight separations are preferred. The gels are stained with EtBr and photographed.
  • a nylon membrane is prepared by soaking it in water for at least 5 min, then in 6X SSC for at least 15 min. before use. (20x SSC is 175.3 g NaCl, 88.2 g sodium citrate per liter, adjusted to pH 7.0.)
  • the nylon membrane is placed on top of the gel and all bubbles in between are removed.
  • the DNA is blotted from the gel to the membrane using an absorbent medium, such as paper toweling and 6x SCC buffer. After the transfer, the membrane may be lightly brushed with a gloved hand to remove any agarose sticking to the surface .
  • the DNA is then fixed to the membrane by UV crosslinking and baking at 80 ° C.
  • the membrane is stored at 4°C until use.
  • the template DNA is amplified using a Perkin Elmer 9700 PCR machine:
  • Arabidopsis DNA is used in the present experiment, but the procedure is a general one. The procedure can be adapted to a multi-well format if necessary.
  • the product of the PCR is analyzed by electrophoresis in a 1% agarose gel.
  • a linearized plasmid DNA can be used as a quantification standard (usually at 50, 100, 200, and 400 ng) . These will be used as references to approximate the amount of PCR products.
  • Hindlll-digested Lambda DNA is useful as a molecular weight marker.
  • the gel can be run fairly quickly; e.g., at 100 volts.
  • the standard gel is examined to determine that the size of the PCR products is consistent with the expected size and if there are significant extra bands or smeary products in the PCR reactions.
  • the amounts of PCR products can be estimated on the basis of the plasmid standard.
  • a small amount of DNA from bands with the correct size can be isolated by dipping a sterile 10- ⁇ l tip into the band while viewing though a UV Transilluminator.
  • the small amount of agarose gel (with the DNA fragment) is used in the labeling reaction.
  • 10X dNTP + DIG-11-dUTP [1:5]: (2 mM dATP, 2 mM dCTP, 2 mM dGTP, 1.65 mM dTTP, 0.35 mM DIG-11-dUTP) 10X dNTP + DIG-11-dUTP [1:10]: (2 mM dATP, 2 mM dCTP, 2 mM dGTP, 1.81 mM dTTP, 0.19 mM DIG-11-dUTP)
  • TE buffer (10 mM Tris, 1 mM EDTA, pH 8)
  • Maleate buffer In 700 ml of deionized distilled water, dissolve 11.61 g maleic acid and 8.77 g NaCl. Add NaOH to adjust the pH to 7.5. Bring the volume to 1 L. Stir for 15 min. and sterilize.
  • 10% blocking solution In 80 ml deionized distilled water, dissolve l.l ⁇ g maleic acid. Next, add NaOH to adjust the pH to 7.5. Add 10 g of the blocking reagent powder (Boehringer Mannheim, Indianapolis, IN, Cat. no. 1096176) . Heat to 60 ° C while stirring to dissolve the powder. Adjust the volume to 100 ml with water. Stir and sterilize.
  • 1% blocking solution Dilute the 10% stock to 1% using the maleate buffer.
  • Buffer 3 (100 mM Tris, 100 mM NaCl, 50 mM MgCl 2 , pH9.5). Prepared from autoclaved solutions of IM Tris pH 9.5, 5 M NaCl, and 1 M MgCl 2 in autoclaved distilled water. Procedure :
  • PCR reactions are performed in 25 ⁇ l volumes containing:
  • the PCR reaction uses the following amplification cycles:
  • the products are analyzed by electrophoresis- in a 1% agarose gel, comparing to an aliquot of the unlabelled probe starting material.
  • the amount of DIG-labeled probe is determined as follows :
  • Serial dilutions e.g., 1:50, 1:2500, 1:10,000
  • Serial dilutions e.g., 1:50, 1:2500, 1:10,000
  • the membrane is fixed by UV crosslinking.
  • d. The membrane is wetted with a small amount of maleate buffer and then incubated in 1% blocking solution for 15 min at room temp.
  • Blocking Reagent In 80 ml deionized distilled water, dissolve 1.16 g maleic acid. Next, add NaOH to adjust the pH to 7.5. Add 10 g of the blocking reagent powder. Heat to 60°C while stirring to dissolve the powder. Adjust the volume to 100 ml with water. Stir and sterilize.
  • wash solutions must be prewarmed to 60 ° C. Use about 100 ml of wash solution per membrane.
  • Buffer 1 Maleic acid buffer (0.1 M maleic acid, 0.15 M NaCl; adjusted to pH 7.5 with NaoH)
  • Washing buffer Maleic acid buffer with 0.3% (v/v) Tween 20.
  • Buffer 2 (IX blocking solution): Dilute the stock solution 1:10 in
  • Detection buffer 0.1 M Tris, 0.1 M NaCl, pH 9.5
  • Buffer 2 (1:10,000) in Buffer 2 is used for detection. 75 ml of solution can be used for 3 blots.
  • the membrane are washed twice in washing buffer with gentle shaking. About 250 mis is used per wash for 3 blots .
  • the blots are equilibrated for 2-5 min in 60 ml detection buffer.
  • Bags (one for detection and one for exposure) should be cut and ready before doing the following steps. .
  • the blot is carefully removed from the detection buffer and excess liquid removed without drying the membrane.
  • the blot is immediately placed in a bag and 1.5 ml of CSPD solution is added.
  • the CSPD solution can be spread over the membrane. Bubbles present at the edge and on the surface of the blot should be removed by gentle rubbing.
  • the membrane is incubated for 5 min. in CSPD solution.
  • Example 2 Transformation of Carrot Cells Transformation of plant cells can be accomplished by a number of methods, as described above. Similarly, a number of plant genera can be regenerated from tissue culture following transformation. Transformation and regeneration of carrot cells as described herein is illustrative.
  • Single cell suspension cultures of carrot (Daucus carota ) cells are established from hypocotyls of cultivar Early France in B 5 growth medium (O.L. Gamborg et al., Plant Physiol . 45:372 (1970)) plus 2,4-D and 15 mM CaCl 2 (B 5 -44 medium) by methods known in the art. The suspension cultures are subcultured by adding 10 ml of the suspension culture to 40 ml of B 5 -44 medium in 250 ml flasks every 7 days and are maintained in a shaker at 150 rpm at 27 °C in the dark.
  • the suspension culture cells are transformed with exogenous DNA as described by Z. Chen et al . Plant Mol . Bio. 3_6:163 (1998). Briefly, 4-days post-subculture cells are incubated with cell wall digestion solution containing 0.4 M sorbitol, 2% driselase, 5mM MES (2- [N-Morpholino] ethanesulfonic acid) pH 5.0 for 5 hours. The digested cells are pelleted gently at 60 xg for 5 min. and washed twice in W5 solution containing 154 mM NaCl, 5 mM KCl, 125 mM CaCl 2 and 5mM glucose, pH 6.0.
  • the protoplasts are suspended in MC solution containing 5 mM MES, 20 mM CaCl 2 , 0.5 M mannitol, pH 5.7 and the protoplast density is adjusted to about 4 x 10 6 protoplasts per ml. 15-60 ⁇ g of plasmid DNA is mixed with 0.9 ml of protoplasts. The resulting suspension is mixed with 40% polyethylene glycol (MW 8000, PEG 8000), by gentle inversion a few times at room temperature for 5 to 25 min. Protoplast culture medium known in the art is added into the PEG-DNA- protoplast mixture. Protoplasts are incubated in the culture medium for 24 hour to 5 days and cell extracts can be used for assay of transient expression of the introduced gene.
  • MC solution containing 5 mM MES, 20 mM CaCl 2 , 0.5 M mannitol, pH 5.7 and the protoplast density is adjusted to about 4 x 10 6 protoplasts per ml. 15-60 ⁇ g of plasmid DNA
  • transformed cells can be used to produce transgenic callus, which in turn can be used to produce transgenic plants, by methods known in the art. See, for example, Nomura and Komamine, Pi t . Phys . 79:988-991 (1985), Identifica tion and Isola tion of Single Cells tha t Produce Soma tic Embryos in Carrot Suspension Cul tures .

Abstract

The present invention provides DNA molecules that constitute portions of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for expressing a gene product, either as a promoter or as a structural gene or as an UTR or as a 3' termination sequence and are also useful in controlling expression of the target gene or as tools for genetic mapping or identification of a particular individual plant or for clustering of a group of plants with a common trait.

Description

SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING
POLYPEPTIDES ENCODED THEREBY
FIELD OF THE INVENTION The present invention relates to isolated polynucleotides that encode all, or a portion of, a gene that is expressed and the corresponding polypeptide. The present invention also relates to isolated polynucleotides that encode regulatory regions of genes.
DESCRIPTION OF THE RELATED ART
Efforts to map and sequence the genome of a number of organisms are in progress; a few complete genome sequences, for example those of E. coli and Saccharomyces cerevisiae are known
(Blattner et al., Science 277:1453 (1997); Goffeau et al., Science 274 : 546 (1996)). The complete genome of a multicellular organism, C. elegans, has also been sequenced
(See, the C. elegans Sequencing Consortium, Science 282 : 2012
(1998)) . To date, no complete genome of a plant has been sequenced, nor has a complete cDNA complement of any plant been sequenced.
SUMMARY OF THE INVENTION
The present invention comprises polynucleotides, such as complete cDNA sequences and/or sequences of genomic DNA encompassing complete genes, portions of genes, and/or intergenic regions, hereinafter collectively referred to as "Sequence-Determined DNA Fragments" (SDFs), from plants, particularly corn and Arabidopsis thaliana and polypeptides derived therefrom. In some instances, the SDFs span the entirety of a protein-coding segment. In some instances, the entirety of an mRNA is represented. Other objects of the invention are the control sequences, such as but not limited to promoters, that are also represented by SDFs of the invention. Complements of any sequence of the invention are also considered part of the invention. Other objects of the invention are polynucleotides comprising exon sequences, polynucleotides comprising intron sequences, polynucleotides comprising introns together with exons, intron/exon junction sequences, 5' untranslated sequences, and 3' untranslated sequences of the SDFs of the present invention. Polynucleotides representing the joinder of any exons described herein, in any arrangement, for example, to produce a sequence encoding any desirable amino acid sequence are within the scope of the invention. The present invention also resides in probes useful for isolating and identifying nucleic acids that hybridize to an SDF of the invention. The probes are typically of a length of 12 to 2000 nucleotides long; more typically, 15 to 200 nucleotides long; even more typically, 18 to 100 nucleotides long.
Yet another object of the invention is a method of isolating and/or identifying nucleic acids using the following steps:
(a) contacting a probe of the instant invention with a polynucleotide sample under conditions that permit hybridization and formation of a polynucleotide duplex; and
(b) detecting and/or isolating the duplex of step (a) . The conditions for hybridization can be from low to moderate to high stringency conditions. The sample can include a polynucleotide having a sequence unique in a plant genome. Probes and methods of the invention are useful, for example, without limitation, for mapping of genetic traits and/or for positional cloning of a desired portion of genomic DNA.
Probes and methods of the invention can also be used for detecting alternatively spliced messages within a species. Probes and methods of the invention can further be used to detect or isolate related genes in other plant species using genomic DNA (gDNA) and/or cDNA libraries. In some instances, especially when longer probes and low to moderate stringency hybridization conditions are used, the probe will hybridize to a plurality of cDNA and/or gDNA sequences of a plant. This approach is useful for isolating representatives of gene families which are identifiable by possession of a common functional domain in the gene product or which have common cis- acting regulatory sequences. This approach is also useful for identifying orthologous genes from other organisms, which can be more or less related to corn, Arabidopsis, or another plant.
The present invention also resides in constructs for modulating the expression of the genes comprised of all or a portion of an SDF. The constructs comprise all or a portion of the expressed SDF, or of a complementary sequence. Examples of constructs include ribozymes comprising RNA encoded by an SDF or by a sequence complementary thereto, antisense constructs, constructs comprising coding regions or parts thereof, constructs comprising promoters, introns, untranslated regions, etc. When inserted into a host cell the construct is, preferably, functionally integrated with or operatively linked to a heterologous polynucleotide. For instance, a coding region from an SDF might be operably linked to a promoter that is functional in a plant.
The present invention also resides in host cells, including bacterial or yeast cells or plant cells, and transgenic plants that harbor constructs such as described above. Another aspect of the invention relates to methods for modulating expression of specific genes in transgenic plants by expression of the structural gene component of the constructs, by regulation of expression of one or more endogenous genes in a transgenic plant or by suppression of expression of the polynucleotides of the invention in a transgenic plant. Methods of modulation of gene expression include without limitation (1) inserting into a host cell additional copies of a polynucleotide comprising a coding sequence; (2) modulating an endogenous promoter in a host cell; (3) inserting antisense or ribozyme constructs into a host cell and (4) inserting into a host cell a polynucleotide comprising a sequence encoding a mutant, fragment, or fusion of the native polypeptides of the instant invention.
BRIEF DESCRIPTION OF THE TABLES
The sequences of exemplary SDFs and polypeptides encoded thereby of the instant invention are listed in SEQ TABLES 1 and 2; annotation relevant to the sequences shown in SEQ TABLES 1 and 2 is presented in REF TABLES 1 and 2. Each sequence corresponds to a Maximum Length cDNA Polynucleotide Sequence. Each Maximum Length cDNA Polynucleotide Sequence (Ac) corresponds to at least one sequence in SEQ TABLE 1 and 2. REF TABLE 1 corresponds with SEQ TABLE 1; REF TABLE 2 corresponds with SEQ TABLE 2.
REF TABLES 1 and 2 are Reference Tables which correlate each of the sequences and SEQ ID NOS in SEQ TABLES 1 and 2 with a corresponding Maximum Length cDNA Sequence (Ac) , Ceres
(Applicant) sequence identifier and other information about the individual sequence. SEQ TABLES 1 and 2 are Sequence Tables containing the sequence of each nucleic acid and amino acid sequence.
In REF TABLES 1 and 2, each section begins by identifying the Maximum Length cDNA Polynucleotide Sequence, indicating a "Clone ID" that is a number used for identification purposes by the applicant and in some instances a "Public Genomic DNA" sequence, indicated by a "gi No" . In those instances where a public sequence is recited, there follows information about gene annotations such as predicted exons. In this portion, after the description of the gene's functional unit, the starting and ending nucleotide number of the public sequence and the computer program used to generate the result are listed. " INIT" denotes an initial exon. " INTR" denotes an internal exon. 5 "TERM" denotes a terminal exon. For those sequences where the computer program is identified as "OCKHAM", "INIT" denotes the first detected exon and "TERM" denotes the last detected exon. "SINGLE" denotes the entire mRNA coding portion is in one exon. Other notations are considered intuitive to the skilled artisan.
In the next section (Ac) , the cDNA MLS is identified by its SEQ ID NO ("Pat. Appln. SEQ ID NO") and the Ceres sequence identifier ("Ceres seq_id" ) , which is also merely an identifier useful for the applicant. The designation of "Alternative transcription start sites" can include both positive and negative numbers. Positive numbers refer to the referenced SEQ ID NO directly. The positions indicated by negative numbers, if any, refer to positions in the public genomic sequences. In instances where there is a "Public
Genomic DNA" referenced, the relevant genomic sequence can be found by direct reference to the nucleotide sequence indicated by the "gi" number shown for the Public Genomic DNA. In instances where there is no Public Genomic DNA referenced, the relevant nucleotide sequence for alignment is the nucleotide sequence associated with the amino acid sequence designated by a "gi" number in the section (Dp). In these instances, the nucleotide sequence is found in GENBANK by clicking on the link in the National Center for Biotechnology Information Entrez database. The numbering is relative to position 1 as determined by aligning the first residue of the MLS cDNA sequence (SEQ ID NO *) with the genomic sequence corresponding to the relevant "gi" number.
Subsection (B) lists SEQ ID NOS and Ceres seq_ids for polypeptide sequences encoded by the cDNA sequence and the location of the start codon within the cDNA sequence that codes for the polypeptide. Subsection (B) also describes additional features within the polypeptide sequence. Subsection (C) provides information regarding identified domains (where present) within the polypeptide and (where present) a name for the polypeptide. Subsection (Dp) provides
(where present) information concerning amino acid sequences that are found to be related and have some sequence identity to the polypeptide sequences of SEQ TABLES 1 and 2. Those
"related" sequences are identified by a "gi" number and are amino acid sequences in the publicly accessible BLAST databases on the NCBI FTP web site (accessible at ncbi.nlm.gov/blast). The database at the NCBI FTP site utilizes the "gi" identifiers to assign by NCBI a unique identifier for each sequence in the databases, thereby providing a non-redundant database for sequences from various databases, including GenBank, EMBL, DBBJ (DNA Database of Japan) and PDB (Brookhaven Protein Data Bank) . Subsection
(Ba) , when present, describes a sequence as being considered plant-specific (i.e. a gene found only in a plant) or describes a bichemical activity for the protein encoded by the exemplary SDF. Subsection (Dn) provides polynucleotide sequences (where present) related to the Maximum Length cDNA sequence .
DETAILED DESCRIPTION OF THE INVENTION
The invention relates to (I) polynucleotides and methods of use thereof, such as IA. Probes, Primers and Substrates;
IB. Methods of Detection and Isolation; B.l. Hybridization; B.2. Methods of Mapping; B.3. Southern Blotting; B.4. Isolating cDNA from Related Organisms;
B.5. Isolating and/or Identifying Orthologous Genes IC. Methods of Inhibiting Gene Expression Cl. Antisense C.2. Ribozyme Constructs;
C.3. Co-Suppression;
C.4. Other Methods to Inhibit Gene Expression ID. Methods of Functional Analysis; IE. Promoter Sequences and Their Use;
IF. UTR' s and/or Intron Sequences and Their Use; and IG. Coding Sequences and Their Use.
The specification also discloses (II) polypeptides including, without limitation, native proteins, mutants, fragments, and fusions. Antibodies to said polypeptides are also disclosed.
The specification also discloses (III) methods of modulating polypeptide production or activity. Examples of such methods include (i) suppressed, (ii) enhanced, and (iii) directed expression.
The specification also discloses (IV) gene constructs and construction of expression vectors, including (IVA) coding sequences and (IVB) promoters, and (IVC) Signal Peptides, (V) transformation procedures to illustrate the invention by way of examples .
I . Polynucleotides
A number of the nucleotide sequences disclosed in SEQ TABLES 1 AND 2 herein as representative of the SDFs of the invention can be obtained by sequencing genomic DNA (gDNA) and/or cDNA from corn plants grown from HYBRID SEED # 35A19, purchased from Pioneer Hi-Bred International, Inc., Supply Management, P.O. Box 256, Johnston, Iowa 50131-0256.
Exemplified SDFs of the invention represent portions of the genome of corn or Arabidopsis and/or represent mRNA expressed from that genome. The isolated nucleic acid of the invention also encompasses corresponding portions of the genome and/or cDNA complement of other organisms as described in detail below.
Starting material for cDNA synthesis for the exemplary corn cDNA clones having sequences presented in SEQ TABLES 1 AND 2 was poly (A) -containing polysomal mRNAs from inflorescences and root tissues of corn plants grown from
HYBRID SEED # 35A19. Male inflorescences and female (pre-and post-fertilization) inflorescences were isolated at various stages of development. Selection for poly (A) containing polysomal RNA was done using oligo d(T) cellulose columns, as described by Cox and Goldberg, "Plant Molecular Biology: A Practical Approach", pp. 1-35, Shaw ed., c. 1988 by IRL, Oxford.
Tissues were or each organ was individually pulverized and frozen in liquid nitrogen. Next, the samples were homogenized in the presence of detergents and then centrifuged. The debris and nuclei were removed from the sample and more detergents were added to the sample. The sample was centrifuged and the debris was removed. Then the sample was applied to a 2M sucrose cushion to isolate polysomes. The RNA was isolated by treatment with detergents and proteinase K followed by ethanol precipitation and centrifugation. The polysomal RNA from the different tissues was pooled according to the following mass ratios: 15/15/1 for male inflorescences, female inflorescences and root, respectively. The pooled material was then used for cDNA synthesis by the methods described below.
The quality and the integrity of the polyA+ RNAs were evaluated. A number of the nucleotide sequences disclosed in SEQ TABLES 1 AND 2 herein as representative of the SDFs of the invention can also be obtained by sequencing genomic DNA from Arabidopsis thaliana , Wassilewskija ecotype or by sequencing cDNA obtained from mRNA from such plants as described below. This is a true breeding strain. Seeds of the plant are available from the Arabidopsis Biological Resource Center at the Ohio State University, under the accession number CS2360.
Seeds of this plant were deposited under the terms and conditions of the Budapest Treaty at the American Type Culture
Collection, Manassas, VA on August 31, 1999, and were assigned
ATCC No. PTA-595.
Starting material for cDNA synthesis for the exemplary
Arabidopsis cDNA clones having sequences presented in SEQ TABLES 1 AND 2 was polysomal RNA isolated from the top-most inflorescence tissues and roots of Arabidopsis thaliana Landsberg erecta (L. er.) also obtained from the Arabidopsis Biological Resource Center. Nine parts inflorescence to every part root was used, as measured by mass. Tissue was pulverized and exposed to liquid nitrogen. Next, the sample was homogenized in the presence of detergents and then centrifuged. The debris and nuclei were removed from the sample and more detergents were added to the sample. The sample was centrifuged ind the debris was removed and the sample was applied to a 2M sucrose cushion to isolate polysomal RNA. Cox et al., "Plant Molecular Biology: A Practical Approach", pp. 1-35, Shaw ed., c. 1988 by IRL, Oxford. The polysomal RNA was used for cDNA synthesis by the methods described below. Polysomal mRNA was then isolated as described above for corn cDNA. The quality of the RNA was assessed electrophoretically .
Following preparation of the mRNAs from various tissues as described above, selection of mRNA with intact 5' ends and specific attachment of an oligonucleotide tag to the 5' end of such mRNA was performed using either a chemical or enzymatic approach. Both techniques take advantage of the presence of the "cap" structure, which characterizes the 5' end of most intact mRNAs and which comprises a guanosine generally methylated once, at the 7 position. The chemical modification approach involves the optional elimination of the 2', 3'-cis diol of the 3' terminal ribose, the oxidation of the 2', 3'-cis diol of the ribose linked to the cap of the 5' ends of the mRNAs into a dialdehyde, and the coupling of the such obtained dialdehyde to a derivatized oligonucleotide tag. Further detail regarding the chemical approaches for obtaining mRNAs having intact 5' ends are disclosed in International Application No. W096/34981 published
November 7, 1996. The enzymatic approach for ligating the oligonucleotide tag to the intact 5' ends of mRNAs involves the removal of the phosphate groups present on the 5' ends of uncapped incomplete mRNAs, the subsequent decapping of mRNAs having intact 5' ends and the ligation of the phosphate present at the 5' end of the decapped mRNA to an oligonucleotide tag. Further detail regarding the enzymatic approaches for obtaining mRNAs having intact 5' ends are disclosed in Dumas Milne Edwards J.B. (Doctoral Thesis of Paris VI University, Le clonage des ADNc complets: difficultes et perspectives nouvelles. Apports pour 1 ' etude de la regulation de 1' expression de la tryptophane hydroxylase de rat, 20 Dec. 1993), EP0 625572 and Kato et al . , Gene 150:243-250 (1994).
In both the chemical e~_rand the enzymatic approach, the oligonucleotide tag has a restriction enzyme site (e.g. an EcoRI site) therein to facilitate later cloning procedures. Following attachment of the oligonucleotide tag to the mRNA, the integrity of the mRNA is examined by performing a Northern blot using a probe complementary to the oligonucleotide tag.
For the mRNAs joined to oligonucleotide tags using either the chemical or the enzymatic method, first strand cDNA synthesis is performed using an oligo-dT primer with reverse transcriptase. This oligo-dT primer can contain an internal tag of at least 4 nucleotides, which can be different from one mRNA preparation to another. Methylated dCTP is used for cDNA first strand synthesis to protect the internal EcoRI sites from digestion during subsequent steps. The first strand cDNA is precipitated using isopropanol after removal of RNA by alkaline hydrolysis to eliminate residual primers. Second strand cDNA synthesis is conducted using a DNA polymerase, such as Klenow fragment and a primer corresponding to the 5' end of the ligated oligonucleotide. The primer is typically 20-25 bases in length. Methylated dCTP is used for second strand synthesis in order to protect internal EcoRI sites in the cDNA from digestion during the cloning process.
Following second strand synthesis, the full-length cDNAs are cloned into a phagemid vector, such as pBlueScript™ (Stratagene) . The ends of the full-length cDNAs are blunted with T4 DNA polymerase (Biolabs) and the cDNA is digested with EcoRI. Since methylated dCTP is used during cDNA synthesis, the EcoRI site present in the tag is the only hemi-methylated site; hence the only site susceptible to EcoRI digestion. In some instances, to facilitate subcloning, an Hind III adapter is added tc the 3' end of full-length cDNAs . The full-length cDNAs are then size fractionated using either exclusion chromatography (AcA, Biosepra) or electrophoretic separation which yields 3 to 6 different fractions. The full-length cDNAs are then directionally cloned either into pBlueScript™ using either the EcoRI and Smal restriction sites or, when the Hind III adapter is present in the full-length cDNAs, the EcoRI and Hind III restriction sites. The ligation mixture is transformed, preferably by electroporation, into bacteria, which are then propagated under appropriate antibiotic selection. Clones containing the oligonucleotide tag attached to full-length cDNAs are selected as follows.
The plasmid cDNA libraries made as described above are purified (e.g. by a column available from Qiagen) . A positive selection of the tagged clones is performed as follows. Briefly, in this selection procedure, the plasmid DNA is converted to single stranded DNA using phage FI gene II endonuclease in combination with an exonuclease (Chang et al.,
Gene 127: 95 (1993)) such as exonuclease III or T7 gene 6 exonuclease. The resulting single stranded DNA is then purified using paramagnetic beads as described by Fry et al . ,
Biotechniques 13: 124 (1992) . Here the single stranded DNA is hybridized with a biotinylated oligonucleotide having a sequence corresponding to the 3' end of the oligonucleotide tag. Preferably, the primer has a length of 20-25 bases. Clones including a sequence complementary to the biotinylated oligonucleotide are selected by incubation with streptavidin coated magnetic beads followed by magnetic capture. After capture of the positive clones, the plasmid DNA is released from the magnetic beads and converted into double stranded DNA using a DNA polymerase such as ThermoSequenase™ (obtained from Amersham Pharmacia Biotech) . Alternatively, protocols such as the Gene Trapper™ kit (Gibco BRL) ca be used. The double stranded DNA is then transformed, preferably by electroporation, into bacteria. The percentage of positive clones having the 5' tag oligonucleotide is typically estimated to be between 90 and 98% from dot blot analysis.
Following transformation, the libraries are ordered in microtiter plates and sequenced. The Arabidopsis library was deposited at the American Type Culture Collection on January 7, 2000 as E-coli liba 010600" under the accession number
Other methods for cloning full-length cDNA are described, for example, by Seki et al., Plant Journal 15: 707- 720 (1998) "High-efficiency cloning of Arabidopsis full- length cDNA by biotinylated Cap trapper"; Maruyama et al., Gene 138 : 171 (1994) "Oligo-capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides" ; and WO 96/34981. It is contemplated that the nucleotide sequences presented herein may contain some small percentage of errors.
These errors may arise in the normal course of determination of nucleotide sequences. Sequence errors can be corrected by obtaining seeds deposited under the accession numbers cited above, propagating them, isolating genomic DNA or appropriate mRNA from the resulting plants or seeds thereof, amplifying the relevant portion of the genomic DNA or mRNA using primers having a sequence that flanks the erroneous sequence, and sequencing the amplification product.
I .A. Probes, Primers and Substrates
SDFs of the invention can be applied to substrates for use in array applications such as, but not limited to, assays of global gene expression, for example under varying conditions of development, growth conditions. The arrays can also be used in diagnostic or forensic methods.
Probes and primers of the instant invention will hybridize to a polynucleotide comprising a sequence in SEQ TABLES 1 AND 2. Though many different nucleotide sequences can encode an amino acid sequence, in some instances, the sequences of SEQ TABLES 1 AND 2 are preferred for encoding polypeptides of the invention. However, the sequence of the probes and/or primers of the instant invention need not be identical to those in SEQ TABLES 1 AND 2 or the complements thereof. For example, some variation in probe or primer sequence and/or length can allow additional family members to be detected, as well as orthologous genes and more taxonomically distant related sequences. Similarly probes and/or primers of the invention can include additional nucleotides that serve as a label for detecting the formed duplex or for subsequent cloning purposes.
Probe length will vary depending on the application. For use as PCR primers, probes should be 12-40 nucleotides, preferably 18-30 nucleotides long. For use in mapping, probes should be 50 to 500 nucleotides, preferably 100-250 nucleotides long. For Southern hybridizations, probes as long as several kilobases can be used as explained below.
The probes and/or primers can be produced by synthetic procedures such as the triester method of Matteucci et al. J.
Am . Chem . Soc . 103 : 318 ( 1981); or according to Urdea et al.
Proc . Na tl . Acad. ^0:7461 (1981) or using commercially available automated oligonucleotide synthesizers.
I . B. Methods of Detection and Isolation
B.l. Hybridization Probes and/or primers can be used for detection and/or isolation of polynucleotide sequences. Such polynucleotides are included in the subject matter of the invention. Depending on the stringency of the conditions under which these probes and/or primers are used, polynucleotides exhibiting a wide range of similarity to those in SEQ TABLES 1 AND 2 can be detected or isolated.
"Stringency" is a function of probe length, probe composition (G + C content) , and salt concentration, organic solvent concentration, and temperature of hybridization or wash conditions. Stringency is typically compared by the parameter "Tm", which is the temperature at which 50% of the complementary molecules in the hybridization are hybridized, in terms of a temperature differential from Tm. High stringency conditions are those providing a condition of Tm - 5°C to Tm - 10°C. Medium stringency conditions are those providing Tm - 20°C to Tm - 29°C. Low stringency conditions are those providing a condition of Tm - 40°C to Tm - 48°C. The relationship of hybridization conditions to Tm (in °C) is expressed in the mathematical equation Tm = 81.5 -16.6(log10[Na+] ) + 0.41(%G+C) - (600/N) (1)
where N is the length of the probe. This equation works well for probes 14 to 70 nucleotides in length that are identical to the target sequence. The equation below for Tm of DNA-DNA hybrids is useful for probes in the range of 50 to greater than 500 nucleotides, and for conditions that include an organic solvent (formamide) .
T-. = 81 . 5 + 16 . 6 log { [Na+ ] / { 1 + 0 . 7 [Na+ ] ) } + 0 . 41 ( %G+C ) -500/L 0 . 63 ( % f ormεmide ) ( 2 )
where L is the length of the probe in the hybrid. (P. Tijessen, "Hybridization with Nucleic Acid Probes" in Laboratory Techniques in Biochemistry and Molecular Biology, P.C. vand der Vliet, ed. , c. 1993 by Elsevier, Amsterdam.) The Tm of equation (2) is affected by the nature of the hybrid; for DNA-RNA hybrids Tm is 10-15°C higher than calculated, for RNA-RNA hybrids Tm is 20-25°C higher. Because the Tm decreases about 1 °C for each 1% decrease in homology when a long probe is used (Bonner et al . , J. Mol . Biol . 8_1:123 (1973)), stringency conditions can be adjusted to favor detection of identical genes or related family members. Equation (2) is derived assuming equilibrium and therefore, hybridizations according to the present invention are most preferably performed under conditions of probe excess and for sufficient time to achieve equilibrium. The time required to reach equilibrium can be shortened by inclusion of a "hybridization accelerator" such as dextran sulfate or another high volume polymer in the hybridization buffer.
When the practitioner wishes to examine the result of membrane hybridizations under a variety of stringencies, an efficient way to do so is to perform the hybridization under a low stringency condition, then to wash the hybridization membrane under increasingly stringent conditions. With respect to wash steps, preferred stringencies lie within the ranges stated above; high stringency is 5-8°C below Tm, medium stringency is 26-29°C below Tm and low stringency is 45-48°C below Tm. A number of methods known to those skilled in the art can be used with the probes and/or primers of the invention to isolate and detect polynucleotides, including, without limitation: Southerns, Northerns, Branched DNA hybridization assays, polymerase chain reaction, and variations thereof. When using SDFs to identify orthologous genes in other species, the practitioner will preferably adjust the amount of target DNA of each species so that, as nearly as is practical, the same number of genome equivalents are present for each species examined. This prevents faint signals from species having large genomes, and thus small numbers of genome equivalents per mass of DNA, from erroneously being interpreted as absence of the corresponding gene in the genome .
A good general discussion of the factors for determining hybridization conditions is provided by Sambrook et al. ("Molecular Cloning, a Laboratory Manual, 2nd ed. , c. 1989 by Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; see esp. , chapters 11 and 12). Additional considerations and details of the physical chemistry of hybridization are provided by G.H. Keller and M.M. Manak "DNA Probes", 2nd Ed. pp. 1-25, c. 1993 by Stockton Press, New York, NY.
Hybridization of one nucleic acid to another constitutes a physical property that defines the subject SDF of the invention. Also, such hybridization imposes structural limitations on the pair. For example, for a probe molecule, given that the sequence of the probe nucleic acid is known and fixed, equation (2) indicates that the combined variation in GC content of the target DNA and mismatch between the probe and the hybridizing DNA is determined for any given hybridization buffer composition and Tm.
The probes and/or primers of the instant invention can be used to detect or isolate nucleotides that are "identical" to the probes or primers. Two nucleic acid sequences or polypeptides are said to be "identical" if the sequence of nucleotides or amino acid residues, respectively, in the two sequences is the same when aligned for maximum correspondence as described below. The term "complementary to" is used herein to mean that the sequence can form a Watson-Crick base pair with a reference polynucleotide sequence. Complementary sequences can include nucleotides, such as inosine, that neither disrupt Watson-Crick base pairing nor contribute to the pairing. Optimal alignment of sequences for comparison may be conducted by the local homology algorithm of Smith and Waterman Add. APL . Ma th . 2:482 (1981), by the homology alignment algorithm of Needleman and Wunsch J. Mol . Biol . 48:443 (1970), by the search for similarity method of Pearson and Lipman Proc. Na tl . Acad. Sci . (USA) 85_: 2444 (1988), by computerized implementations of these algorithms (GAP, BESTFIT, BLAST, PASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group (GCG) , 575 Science Dr., Madison, WI), or by inspection. Given that two sequences have been identified for comparison, GAP and BESTFIT are preferably employed to determine their optimal alignment. Typically, the default values of 5.00 for gap weight and 0.30 for gap weight length are used.
The probes and/or primers of the invention can also be used to detect and/or isolate polynucleotides exhibiting at least 80% sequence identity with the sequences of SEQ TABLES 1 AND 2 or fragments thereof.
"Percentage of sequence identity" is determined by comparing two optimally aligned sequences over a comparison window, wherein the portion of the polynucleotide sequence in the comparison window may comprise additions or deletions
(e.g., gaps or overhangs) as compared to the reference sequence
(which does not comprise additions or deletions) for optimal alignment of the two sequences. The percentage is calculated by determining the number of positions at which the identical nucleic acid base or amino acid residue occurs in both sequences to yield the number of matched positions, dividing the number of matched positions by the total number of positions in the window of comparison and multiplying the result by 100 to yield the percentage of sequence identity. "Percentage of sequence identity" can be determined by the algorithms described above.
The term "substantial identity" between polynucleotide or polypeptide sequences refers to polynucleotide or polypeptide comprising a sequence that has at least 80% sequence identity, preferably at least 85%, more preferably at least 90% and most preferably at least 95%, even more preferably, at least 96%, 97%, 98% or 99% sequence identity compared to a reference sequence using the programs.
Isolated polynucleotides within the scope of the invention also include allelic variants of the specific sequences presented in SEQ TABLES 1 AND 2. An "allelic variant" is a sequence that is a variant from that of the SDF, but represents the same chromosomal locus in the organism. Allelic variants can arise by normal genetic variation in a population. Allelic variants can also be produced by genetic engineering methods. An allelic variant can be one that is found in a naturally occurring plant, including a cultivar or ecotype. A silent allele can give rise to phenotypic and expression profiles. An allelic variant may or may not give rise to a phenotypic change, and may or may not be expressed. An expressed allele can result in a detectable change in the phenotype of the trait represented by the locus. Allelic variations can occur in any portion of the gene sequence, including regulatory regions as well as structural regions.
With respect to nucleotide sequences, degeneracy of the genetic code provides the possibility to substitute at least one base of the base sequence of a gene with a different base without causing the amino acid sequence of the polypeptide produced from the gene to be changed. Hence, the DNA of the present invention may also have any base sequence that has been changed from a sequence in SEQ TABLES 1 AND 2 by substitution in accordance with degeneracy of genetic code.
References describing codon usage include: Carels et al . , J.
Mol . Evol . 46: 45 (1998) and Fennoy et al . , Nucl . Acids Res .
21 (23) : 5294 (1993) .
A. B.2. Mapping
The isolated SDF DNA of the invention can be used to create various types of genetic and physical maps of the genome of corn, Arabidopsis or other plants. Some SDFs may be absolutely associated with particular phenotypic traits, allowing construction of gross genetic maps. While not all SDFs will immediately be associated with a phenotype, all SDFs can be used as probes for identifying polymorphisms associated with phenotypes of interest. Briefly, total DNA is isolated from individuals and is subsequently cleaved with one or more restriction enzymes, separated according to mass, transferred to a solid support, hybridized with SDF DNA and the pattern of fragments compared. Polymorphisms associated with a particular SDF are visualized as differences in the size of fragments produced between individual DNA samples after digestion with a particular restriction enzyme and hybridization with the SDF. After identification of polymorphic SDF sequences, linkage studies can be conducted. Recombinants produced are analyzed using the same restriction enzyme/hybridization procedure. After identification of many polymorphisms using SDF sequences, linkage studies can be conducted by using the individuals showing polymorphisms as parents in crossing programs. F2 progeny recombinants or recombinant inbreds, for example, are then analyzed using the same restriction enzyme/hybridization procedure. The order of DNA polymorphisms along the chromosomes can be inferred based on the frequency with which they are inherited together versus independently. The closer two polymorphisms are together in a chromosome the higher the probability that they are inherited together. Integration of the relative positions of all the polymorphisms and associated marker SDFs produces a genetic map of the species, where the distances between markers reflect the recombination frequencies in that chromosome segment.
The use of recombinant inbred lines for such genetic mapping is described for Arabidopsis by Alonso-Blanco et al .
{Methods in Molecular Biology, vol.82, " Arabidopsis
Protocols" , pp. 137-146, J.M. Martinez-Zapater and J. Salinas, eds., c. 1998 by Humana Press, Totowa, NJ) and for corn by Burr ("Mapping Genes with Recombinant Inbreds", pp.
249-254. In Freeling, M. and V. Walbot (Ed.), The Maize
Handbook, c . 1994 by Springer-Verlag New York, Inc.: New
York, NY, USA; Berlin Germany; Burr et al. Genetics (1998) 118: 519; Gardiner, J. et al . , (1993) Genetics 134: 917).
However, this procedure is not limited to plants and can be used for other organisms (such as yeast) or for individual cells .
The SDFs of the present invention can also be used for simple sequence repeat (SSR) mapping. Rice SSR mapping is described by Morgante et al. ( The Plant Journal (1993) 3:
165), Panaud et al. ( Genome (1995) 38: 1170); Senior et al.
( Crop Science (1996) 36: 1676), Taramino et al . ( Genome
(1996) 39: 277) and Ahn et al . (Molecular and General Genetics (1993) 241: 483-90). SSR mapping can be achieved using various methods. In one instance, polymorphisms are identified when sequence specific probes flanking an SSR contained within an SDF are made and used in polymerase chain reaction (PCR) assays with template DNA from two or more individuals of interest. Here, a change in the number of tandem repeats between the SSR-flanking sequence produces differently sized fragments (U.S. Patent 5,766,847).
Alternatively, polymorphisms can be identified by using the PCR fragment produced from the SSR-flanking sequence specific primer reaction as a probe against Southern blots representing different individuals (U.H. Refseth et al., (1997) Electrophoresis 18: 1519).
Genetic and physical maps of crop species have many uses. For example, these maps can be used to devise positional cloning strategies for isolating novel genes from the mapped crop species. In addition, because the genomes of closely related species are largely syntenic (that is, they display the same ordering of genes within the genome) , these maps can be used to isolate novel alleles from wild relatives of crop species by positional cloning strategies.
The various types of maps discussed above can be used with the SDFs of the invention to identify Quantitative Trait Loci (QTLs) . Many important crop traits, such as the solids content of tomatoes, are quantitative traits and result from the combined interactions of several genes. These genes reside at different loci in the genome, oftentimes on different chromosomes, and generally exhibit multiple alleles at each locus. The SDFs of the invention can be used to identify QTLs and isolate specific alleles as described by de Vicente and Tanksley (Genetics 134:585 (1993)). In addition to isolating QTL alleles present crop species, the SDFs of the invention can also be used to isolate alleles from the corresponding QTL of wild relatives. Transgenic plants having various combinations of QTL alleles can then be created and the effects of the combinations measured. Once an ideal allele combination has been identified, crop improvement can be accomplished either through biotechnological means or by directed conventional breeding programs (for review see Tanksley and McCouch, Science
277:1063 (1997) ) .
In another embodiment the SDFs can be used to help create physical maps of the genome of corn, Arabidopsis and related species. Where SDFs have been ordered on a genetic map, as described above, then SDFs can be used as probes to discover which clones in large libraries of plant DNA fragments in YACs, BACs, etc. contain the same SDF or similar sequences, thereby facilitating the assignment of the large DNA fragments to chromosomal positions. Subsequently, the large BACs, YACs, etc. can be ordered unambiguously by more detailed studies of their sequence composition (e.g. Marra et al. (1997) Genomic Research 7:1072-1084) and by using their end or other sequences to find the identical sequences in other cloned DNA fragments. The overlapping of DNA sequences in this way allows large contigs of plant sequences to be built, that, when sufficiently extended, provide a complete physical map of a chromosome. Sometimes the SDFs themselves will provide the means of joining cloned sequences into a contig.
The patent publication WO95/35505 and U.S. Patents 5,445,943 and 5,410,270 describe scanning multiple alleles of a plurality of loci using hybridization to arrays of oligonucleotides . These techniques are useful for each of the types of mapping discussed above.
Following the procedures described above and using a plurality of the SDFs of the present invention, any individual can be genotyped. These individual genotypes can be used for the identification of particular cultivars, varieties, lines, ecotypes and genetically modified plants or can serve as tools for subsequent genetic studies involving multiple phenotypic traits.
B. 3 Southern Blot Hybridization
The sequences from SEQ TABLES 1 AND 2 can be used as probes for various hybridization techniques. These techniques are useful for detecting target polynucleotides in a sample or for determining whether transgenic plants, seeds or host cells harbor a gene or sequence of interest and thus might be expected to exhibit a particular trait or phenotype.
In addition, the hybridization of the SDFs of the invention to nucleic acids obtained from other organisms can be used to identify orthologous genes from other species and/or additional members of gene families either in the same or different species. In regard to identifying genes in other species, a Southern blot of genomic DNA provides description of isolated DNA fragments that comprise the orthologous genes or additional members of the gene families. That is, given such data, one of ordinary skill in the art could distinguish the isolated DNA fragments by their size together with the restriction sites at each end and by the property of hybridizing with the SDF probe under the stated conditions. In addition, the SDFs from the invention can be used to isolate additional members of gene families from the same species and/or orthologous genes from different species. This is accomplished by hybridizing an SDF to a Southern blot containing the appropriate genomic DNA or cDNA. Given the resulting hybridization data, one of ordinary skill in the art could distinguish and isolate the correct DNA fragments by size, restriction sites and stated hybridization conditions from a gel or from a library. Identification and isolation of orthologous genes from closely related species and alleles within a species is particularly desirable because of their potential for crop improvement. Many important crop traits, such as the solid content of tomatoes, result from the combined interactions of the products of several genes residing at different loci in the genome. Generally, alleles at each of these loci can make quantitative differences to the trait. By identifying and isolating numerous alleles for each locus from within or different species, transgenic plants having various combinations of alleles can be created and the effects of the combinations measured. Once a more favorable ideal allele combination has been identified, crop improvement can be accomplished either through biotechnological means or by directed conventional breeding programs (Tanksley et al. Science 277:1063(1997) ) .
The results from hybridizations of the SDFs of the invention to Southern blots containing DNA from another species can also be used to generate restriction fragment maps for the corresponding genomic regions. These maps provide map provides additional information about the relative positions of restriction sites within fragments, further distinguishing mapped DNA from the remainder of the genome. Physical maps can be made by digesting genomic DNA with different combinations of restriction enzymes.
Probes for Southern blotting to distinguish individual restriction fragments can range in size from 15 to 20 nucleotides to several thousand nucleotides. More preferably, the probe is 100 to 1000 nucleotides long for identifying members of a gene family when it is found that repetitive sequences would complicate the hybridization. For identifying an entire corresponding gene in another species, the probe is more preferably the length of the gene, typically 2000 to 10,000 nucleotides, but probes 50-1,000 nucleotides long might be used. Some genes, however, might require probes up to 15,000 nucleotides long or overlapping probes constituting the full-length sequence to span their lengths.
Also, while it is preferred that the probe be homogeneous with respect to its sequence, that is not necessary. For example, as described below, a probe representing members of a gene family having diverse sequences can be generated using PCR to amplify genomic DNA or RNA templates using primers derived from SDFs that include sequences that define the gene family.
For identifying corresponding genes in another species, the probe for Southern blotting most preferably would be the genomic copy of the probe gene. This allows all elements of the gene to be identified in the other species. The next most preferable probe is a cDNA spanning the entire coding sequence, which allows all of the mRNA-coding portion of the gene to be identified; in this case it is possible that some introns in the gene might be missed. Probes for Southern blotting can easily be generated from SDFs by making primers having the sequence at the ends of the SDF and using corn or Arabidopsis genomic DNA as a template. In instances where the SDF includes sequence conserved among species, primers including the conserved sequence can be used for PCR with genomic DNA from a species of interest to obtain a probe. Similarly, if the SDF includes a domain of interest, that portion of the SDF can be used to make primers and, with appropriate template DNA, used to make a probe to identify genes containing the domain. Alternatively, the PCR products can be resolved, for example by gel electrophoresis, and cloned and/or sequenced. In this manner, the variants of the domain among members of a gene family, both within and across species, can be examined. B.4.1 Isolating DNA from Related Organisms The SDFs of the invention can be used to isolate the corresponding DNA from other organisms. Either cDNA or genomic DNA can be isolated. For isolating genomic DNA, a lambda, cosmid, BAC or YAC, or other large insert genomic library from the plant of interest can be constructed using standard molecular biology techniques as described in detail by Sambrook et al. 1989 (Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, New York) and by Ausubel et al. 1992 (Current Protocols in Molecular Biology, Greene Publishing, New York) .
To screen a phage library, recombinant lambda clones are plated out on appropriate bacterial medium using an appropriate E. coli host strain. The resulting plaques are lifted from the plates using nylon or nitrocellulose filters. The plaque lifts are processed through denaturation, neutralization, and washing treatments following the standard protocols outlined by Ausubel et al. (1992). The plaque lifts are hybridized to either radioactively labeled or non- radioactively labeled SDF DNA at room temperature for about 16 hours, usually in the presence of 50% formamide and 5X SSC (sodium chloride and sodium citrate) buffer and blocking reagents. The plaque lifts are then washed at 42°C with 1% Sodium Dodecyl Sulfate (SDS) and at a particular concentration of SSC. The SSC concentration used is dependent upon the stringency at which hybridization occurred in the initial Southern blot analysis performed. For example, if a fragment hybridized under medium stringency (e.g., Tm - 20°C), then this condition is maintained or preferably adjusted to a less stringent condition (e.g., Tm- 30°C) to wash the plaque lifts. Positive clones show detectable hybridization e.g., by exposure to X-ray films or chromogen formation. The positive clones are then subsequently isolated for purification using the same general protocol outlined above. Once the clone is purified, restriction analysis can be conducted to narrow the region corresponding to the gene of interest. The restriction analysis and succeeding subcloning steps can be done using procedures described by, for example Sambrook et al. (1989) cited above.
To screen a YAC library, the procedures outlined for the lambda library are essentially similar except the YAC clones are harbored in bacterial colonies. The YAC clones are plated out at reasonable density on nitrocellulose or nylon filters supported by appropriate bacterial medium in petri plates. Following the growth of the bacterial clones, the filters are processed through the denaturation, neutralization, and washing steps following the procedures of Ausubel et al. 1992. The same hybridization procedures for lambda library screening are followed.
To isolate cDNA, similar procedures using appropriately modified vectors are employed. For instance, the library can be constructed in a lambda vector appropriate for cloning cDNA such as λgtll. Alternatively, the cDNA library can be made in a plasmid vector. cDNA for cloning can be prepared by any of the methods known in the art, but is preferably prepared as described above. Preferably, a cDNA library will include a high proportion of full-length clones.
B. 5. Isolating and/or Identifying Orthologous Genes
Probes and primers of the invention can be used to identify and/or isolate polynucleotides related to those in SEQ
TABLES 1 AND 2. Related polynucleotides are those that are native to other plant organisms and exhibit either similar sequence or encode polypeptides with similar biological activity. One specific example is an orthologous gene, a gene that has a high degree of sequence similarity, often along the entire length of the coding portion of the gene, and also encodes a gene product that performs a similar function in the organism. Orthologous genes may be distinguished from homologous genes in that homologous genes share sequence similarity but often only in a portion of the sequence, which often represents a functional domain such as a tyrosine kinase activity, a DNA binding domain, or the like. The functional activities of homologous genes are not necessarily the same, but are the same for orthologous genes. The degree of identity is a function of evolutionary separation and, in closely related species, the degree of identity can be 98 to 100%. The amino acid sequence of a protein encoded by an orthologous gene can be less than 75% identical, but tends to be at least75% or at least 80% identical, more preferably at least 90%, most preferably at least 95% identical to the amino acid sequence of the reference protein.
To find orthologous genes, the probes are hybridized to nucleic acids from a species of interest under low stringency conditions and blots are then washed under conditions of increasing stringency. It is preferable that the wash stringency be such that sequences that are 85 to 100% identical will hybridize. More preferably, sequences 90 to 100% identical will hybridize and most preferably only sequences greater than 95% identical will hybridize. The low stringency condition is preferably one where sequences containing as much as 40-45% mismatches will be able to hybridize. This condition is established by Tm - 40°C to Tm - 48°C ( see below) . One of ordinary skill in the art will recognize that, due to degeneracy in the genetic code, amino acid sequences that are identical can be encoded by DNA sequences as little as 67% identical. Thus, it is preferable to make an overlapping series of shorter probes, on the order of 24 to 45 nucleotides, and individually hybridize them to the same arrayed library to avoid the problem of degeneracy introducing large numbers of mismatches.
As evolutionary divergence increases, genome sequences also tend to diverge. Thus, one of skill will recognize that searches for orthologous genes between more divergent species will require the use of lower stringency conditions compared to searches between closely related species. Also, degeneracy is more of a problem for searches in the genome of a species more distant evolutionarily from the species that is the source of the SDF probe sequences.
Therefore the method described in Bouckaert et al., U.S. Ser. No. 60/121,700 Atty. Dkt. No. 2750-117P, Client Dkt. No. 00010.001, filed February 25, 1999, hereby incorporated in its entirety by reference, can be applied to the SDFs of the present invention to isolate related genes from plant species which do not hybridize to the corn or Arabidopsis sequences of SEQ TABLES 1 AND 2.
Identification of the relationship of nucleotide or amino acid sequences among plant species can be done by comparison of the subject nucleotide or amino acid sequence to the sequences of SDFs of the present application presented in SEQ TABLES 1 and 2.
The SDFs of the invention can also be used as probes to search for genes that are related to the SDF within a species. Such related genes are typically considered to be members of a "gene family." In such a case, the sequence similarity will often be concentrated into one or a few portions of the sequence. The portions of similar sequence that define the gene family typically encode a portion of a protein or RNA that has an enzymatic or structural function. The degree of identity in the amino acid sequence of the domain that defines the gene family is preferably at least 70%, more preferably 80 to 95%, most preferably 85 to 99%. To search for members of a gene family within a species, a "low stringency" hybridization is usually performed, but this will depend upon the size, distribution and degree of sequence divergence of domains that define the gene family.
SDFs encompassing regulatory regions can be used to identify "coordinately expressed" genes by using the regulatory region portion of the SDF as a probe.
In the instances where the SDFs are identified as being expressed from genes that confer a particular phenotype, then the SDFs can also be used as probes to assay plants of different species for those phenotypes.
I.C. Methods to Inhibit Gene Expression
In some instances it is desirable to suppress expression of an endogenous or exogenous gene. A well-known instance is the FLAVOR-SAVOR™ tomato, in which the gene encoding ACC synthase is inactivated by an antisense approach, thus delaying softening of the fruit after ripening. See for example, U.S. Patent No. 5,859,330; U.S. Patent No. 5,723,766; Oeller, et al, Science, 254:437-439(1991); and Hamilton et al, Na ture, 346:284-287 (1990). Also, timing of flowering can be controlled by suppression of the FLOWERING LOCUS C; high levels of this transcript are associated with late flowering, while absence of FLC is associated with early flowering (S.D. Michaels et al., Plant Cell 11:949 (1999). Also, the transition of apical meristem from production of leaves with associated shoots to flowering is regulated by TERMINAL FLOWER1 , APETALA1 and LEAFY. Thus, when it is desired to induce a transition from shoot production to flowering, it is desirable to suppress TFL1 expression (S.J. Liljegren, Plan t Cell 11:1007 (1999)). As another instance, it has been found that suppression of the ethylene forming enzyme results in arrested ovule development and female sterility that can be reversed by application of ethylene (D. De Martinis et al., Plant Cell 11:1061 (1999)). The ability to manipulate fertility of female plants is useful in ;e&e increasing fruit production and creating hybrids.
In an instance when it is desired to express a dominant negative mutation, it often helpful to suppress expression of the endogenous, native protein. Expression of dominant negative mutant proteins is a useful tool for research, for example when a dominant negative mutation of a receptor is used to constitutively activate or suppress a signal transduction cascade, allowing examination of the phenotype and thus the trait (s) controlled by that receptor and pathway.
C .1 Antisense
In the case of polynucleotides used to inhibit expression of an endogenous gene, the introduced sequence need not be perfectly identical to a sequence of the target endogenous gene. The introduced polynucleotide sequence will typically be at least substantially identical (as determined above) to the target endogenous sequence.
Some polynucleotide SDFs in SEQ TABLES 1 AND 2 represent sequences that are expressed in corn and/or Arabidopsis .
Thus the invention includes using these sequences to generate antisense constructs to inhibit transcription and/or translation of said SDFs, typically in a plant cell.
To accomplish this, a polynucleotide segment from the desired gene that can hybridize to the mRNA expressed from the desired gene (the "antisense segment") is operably linked to a promoter such that the antisense strand of RNA will be transcribed when the construct is present in a host cell. A regulated promoter can be used in the construct to control transcription of the antisense segment so that transcription occurs only under desired circumstances.
The antisense segment to be introduced generally will be substantially identical to at least a portion of the endogenous gene or genes to be repressed. The sequence, however, need not be perfectly identical to inhibit expression. Further, the antisense product may hybridize to the untranslated region instead of or in addition to the coding portion of the gene. The vectors of the present invention can be designed such that the inhibitory effect applies to other proteins within a family of genes exhibiting homology or substantial homology to the target gene.
For antisense suppression, the introduced antisense segment sequence also need not be full length relative to either the primary transcription product or fully processed mRNA. Generally, higher sequence identity can be used to compensate for the use of a shorter sequence. Furthermore, the introduced sequence need not have the same intron or exon pattern, and homology of non-coding segments may be equally effective. Normally, a sequence of between about 30 or 40 nucleotides and the full length of the transcript should be used, though a sequence of at least about 100 nucleotides is preferred, a sequence of at least about 200 nucleotides is more preferred, and a sequence of at least about 500 nucleotides is especially preferred.
C .2. Ribozymes
It is also contemplated that gene constructs representing ribozymes and based on the SDFs in SEQ TABLES 1 AND 2 are an object of the invention. Ribozymes can also be used to inhibit expression of genes by suppressing the translation of the mRNA into a polypeptide. It is possible to design ribozymes that specifically pair with virtually any target RNA and cleave the phosphodiester backbone at a specific location, thereby functionally inactivating the target RNA. In carrying out this cleavage, the ribozyme is not itself altered, and is thus capable of recycling and cleaving other molecules, making it a true enzyme. The inclusion of ribozyme sequences within antisense RNAs confers RNA-cleaving activity upon them, thereby increasing the activity of the constructs.
A number of classes of ribozymes have been identified.
One class of ribozymes is derived from a number of small circular RNAs, which are capable of self-cleavage and replication in plants. The RNAs replicate either alone
(viroid RNAs) or with a helper virus (satellite RNAs) .
Examples include RNAs from avocado sunblotch viroid and the satellite RNAs from tobacco ringspot virus, lucerne transient streak virus, velvet tobacco mottle virus, solanum nodiflorum mottle virus and subterranean clover mottle virus. The design and use of target RNA-specific ribozymes is described in Haselhoff et al . Nature, 334:585 (1988).
Like the antisense constructs above, the ribozyme sequence portion necessary for pairing need not be identical to the target nucleotides to be cleaved, nor identical to the sequences in SEQ TABLES 1 AND 2. Generally, the sequence in the ribozyme capable of binding to the target sequence exhibits substantial sequence identity to a sequence in SEQ TABLES 1 AND 2 or the complement thereof, or to a portion of said sequence or complement. Further, the ribozyme sequence also need not be full length relative to either the primary transcription product or fully processed mRNA. The ribozyme can be equally effective in inhibiting mRNA translation by cleaving either in the untranslated or coding regions. Generally, higher sequence identity can be used to compensate for the use of a shorter sequence. Furthermore, the introduced sequence need not have the same intron or exon pattern, and homology of non-coding segments may be equally effective.
C.3. Sense Suppression
Another method of suppression is by introducing an exogenous copy of the gene to be suppressed. Introduction of expression cassettes in which a nucleic acid is configured in the sense orientation with respect to the promoter into the chromosome of a plant or by a self-replicating virus has been shown to be an effective means by which to induce degradation of mRNAs of target genes. For an example of the use of this method to modulate expression of endogenous genes see, Napoli et al., The Plant Cell 2:279 (1990), and U.S. Patents Nos.
5,034,323, 5,231,020, and 5,283,184. Generally, where inhibition of expression is desired, some transcription of the introduced sequence is probably necessary. The effect may occur where the introduced sequence contains no coding sequence per se, but comprises only intron or untranslated sequences homologous to sequences present in the primary transcript of the endogenous sequence. The introduction of only regulatory promoter sequences can also cause interference with the activity of endogenous promoters possessing the same sequence. Thus, the described SDFs can also be used to control transcription. In all of these procedures, the introduced sequence generally will be substantially identical to the endogenous sequence intended to be inactivated. The minimal identity will typically be greater than about 65%, but a higher identity might exert a more effective repression of expression of the endogenous sequences. Sequence identity of more than about 80% is preferred, though about 95% to absolute identity would be most preferred. As with antisense regulation, the effect would likely apply to any other proteins within a similar family of genes exhibiting homology or substantial homology to the suppressing sequence.
C .4. Other Methods to Inhibit Gene Expression Yet another means of suppressing gene expression is to insert a polynucleotide into the gene of interest to disrupt transcription or translation of the gene. Low frequency homologous recombination can be used to target a polynucleotide insert to a gene by flanking the polynucleotide insert with sequences that are substantially similar to the gene to be disrupted. Sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto can be used for homologous recombination.
In addition, random insertion of polynucleotides into a host cell genome can also be used to disrupt the gene of interest. Azpiroz-Leehan et al., Trends in Genetics 13: 152 (1997). In this method, screening for clones from a library containing random insertions is preferred to identifying those that have polynucleotides inserted into the gene of interest. Such screening can be performed using probes and/or primers described above based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto. The screening can also be performed by selecting clones or Ri plants having a desired phenotype.
I . D. Methods of Functional Analysis
The constructs described in the methods under I.C. above can be used to determine the function of the polypeptide encoded by the gene that is targeted by the constructs.
Down-regulating the transcription and translation of the targeted gene, the host cell or organisms, such as a plant, may produce phenotypic changes as compared to a wild-type cell or organism. In addition, in vi tro assays can be used to determine if any biological activity, such as calcium flux, DNA transcription, nucleotide incorporation, etc., are being modulated by the down-regulation of the targeted gene.
Coordinated regulation of sets of genes, e.g., those contributing to a desired polygenic trait, is sometimes necessary to obtain a desired phenotype. SDFs of the invention representing transcription activation and DNA binding domains can be assembled into hybrid transcriptional activators. These hybrid transcriptional activators can be used with their corresponding DNA elements (i.e., those bound by the DNA-binding SDFs) to effect coordinated expression of desired genes (J.J. Schwarz et al., Mol . Cell . Biol . 12:266 (1992), A. Martinez et al., Mol . Gen . Genet . 261:546 (1999)). The SDFs of the invention can also be used in the two- hybrid genetic systems to identify networks of protein- protein interactions (L. McAlister-Henn et al., Methods 19:330 (1999), J.C. Hu et al., Methods 20:80 (2000), M. Golovkin et al., J. Biol . Chem . 27_4:36428 (1999), K. Ichimura et al., Biochem . Biophys . Res . Comm . 253:532 (1998)). The SDFs of the invention can also be used in various expression display methods to identify important protein-DNA interactions (e.g. B. Luo et al., J. Mol . Biol . 266: 479 (1997) ) .
I.E. Promoters
The SDFs of the invention are also useful as structural or regulatory sequences in a construct for modulating the expression of the corresponding gene in a plant or other organism, e.g. a symbiotic bacterium. For example, promoter sequences represented in SEQ TABLES 1 AND 2 can be useful in directing expression of coding sequences either as constitutive promoters or to direct expression in particular cell types, tissues, or organs or in response to environmental stimuli. The term "promoter" refers to a region ofe-3? sequence determinants located upstream or downstream from the start of transcription and which are involved in recognition and binding of RNA polymerase and other proteins to initiate transcription. A "plant promoter" is a promoter capable of initiating transcription in plant cells and can be used to drive expression of a translated portion of an SDF. Such promoters need not be of plant origin. For example, promoters derived from plant viruses, such as the CaMV35S promoter or from Agrobacterium tumefaciens such as the T-DNA promoters, can be plant promoters. A typical example of a constitutive promoter of plant origin is the promoter of the cowpea trypsin inhibitor gene. Typical examples of temporal and/or tissue specific promoters of plant origin that can be used with the polynucleotides of the present invention, are: PTA29, a promoter which is capable of driving gene expression specifically in tapetum and only during anther development
(Koltonow et al . , Plant Cell 2:1201 (1990); RCc2 and RCc3, promoters that direct root-specific gene expression in rice (Xu et al., Plant Mol . Biol . 27:237 (1995); TobRB27, a root- specific promoter from tobacco (Yamamoto et al., Plant Cell 3:371 (1991)).
By "specific promoters" is meant promoters that have a high preference of driving gene expression in the specified tissue and/or at the specified time during the concerned tissue or organ development. By "high preference" is meant at least 3-fold, preferably 5-fold, more preferably at least 10-fold still more preferably at least 20-fold, 50-fold or 100-fold increase in expression in the desired tissue over the expression in any undesired tissue.
A typical example of an inducible promoter, which can be utilized with the polynucleotides of the present invention, is PARSKl, the promoter from the Arabidopsis gene encoding a serine-threonine kinase enzyme, and which promoter is induced by dehydration, abscissic acid and sodium chloride (Wang and Goodman, Plant J. 8:37 (1995)).
With respect to the SDFs of the present invention a promoter is likely to be a relatively small portion of a genomic DNA (gDNA) sequence located in the first 2000 nucleotides upstream from an initial exon identified in a gDNA sequence or initial "ATG" or methionine codon in a corresponding cDNA or mRNA sequence. Such promoters are more likely to be found in the first 1000 nucleotides upstream of an initial ATG or methionine codon of a cDNA sequence corresponding to a gDNA sequence. In particular, the promoter is usually located upstream of the transcription start site.
Such a start site is located at the first exon predicted in the OCKHAM-cDNA predictions. In such an instance, the transcription start site is the first nucleotide of the 5' most exon, if the predictions are in the plus (+) strand, or the 3' most if the predictions are in the minus (-) strand. Alternative transcription start sites may be located between the first nucleotide of the 5' most exon (or the 3' most exon in the minus (-) strand) and the initial ATG or methionine codon in the cDNA sequence. The portions of a particular gDNA sequence that function as a promoter in a plant cell will preferably be found to hybridize at medium or high stringency to gDNA sequences presented in SEQ TABLES 1 AND 2.
Promoters are generally modular in nature. Short DNA sequences representing binding sites for proteins can be separated from each other by intervening sequences of varying length. For example, within a particular functional module protein binding sites may be constituted by regions of 5 to 60, preferably 10 to 30, more preferably 10 to 20 nucleotides. Within such binding sites, there are typically 2 to 6 nucleotides that specifically contact amino acids of the nucleic acid binding protein. The protein binding sites are usually separated from each other by 10 to several hundred nucleotides, typically by 15 to 150 nucleotides, often by 20 to 50 nucleotides. DNA binding sites in promoter elements often display dyad symmetry in their sequence. Often elements binding several different proteins, and/or a plurality of sites that bind the same protein, will be combined in a region of 100 to 1000 basepairs.
Elements that have transcription regulatory function can be isolated from their corresponding endogenous gene, or the desired sequence can be synthesized, and recombined in constructs to direct expression of a structural gene in a desired tissue-specific, temporal-specific or other desired manner of inducibility or suppression. When hybridizations are performed to identify or isolate elements of a promoter by hybridization to the long sequences presented in SEQ TABLES 1 AND 2, conditions should be adjusted to account for the above- described nature of promoters. For example short probes, constituting the element sought, should be used under low temperature and/or high salt conditions. When long probes, which might include several promoter elements are used, low to medium stringency conditions are preferred when hybridizing to promoters across species.
Promoters can consist of a "basal promoter" that functions as a site for assembly of a transcription complex comprising an RNA polymerase, for example RNA polymerase II. A typical transcription complex will include additional factors such as TFΣIB, TFnD, and TFTIE. Of these, TF D appears to be the only one to bind DNA directly. Basal promoters frequently include a "TATA box" element usually located _ ^tween 20 and 35 nucleotides upstream from the site of initiation of transcription. Basal promoters also sometimes include a "CCAAT box" element (typically a sequence CCAAT) and/or a GGGCG sequence, usually located between 40 and 200 nucleotides, preferably 60 to 120 nucleotides, upstream from the start site of transcription.
The promoter might also contain one or more "enhancers" and/or "suppressors" that function as binding sites for additional transcription factors that have the function of modulating the level of transcription with respect to tissue specificity of transcription, transcriptional responses to particular environmental or nutritional factors, and the like.
If a nucleotide sequence of an SDF, or part of the SDF, functions as a promoter or portion of a promoter, then nucleotide substitutions, insertions or deletions that do not substantially affect the binding of relevant DNA binding proteins would be considered equivalent to the exemplified nucleotide sequence. It is envisioned that there are instances where it is desirable to decrease the binding of relevant DNA binding proteins to "silence" or "down-regulate" a promoter, or conversely to increase the binding of relevant
DNA binding proteins to "enhance" or "up-regulate" a promoter. In such instances, polynucleotides representing changes to the nucleotide sequence of the DNA-protein contact region by insertion of additional nucleotides, changes to identity of relevant nucleotides, including use of chemically-modified bases, or deletion of one or more nucleotides are considered encompassed by the present invention. Promoter function can be assayed by methods known in the art, preferably by measuring activity of a reporter gene operatively linked to the sequence being tested for promoter function. Examples of reporter genes include those encoding luciferase, green fluorescent protein, G.'S, neo, cat and bar.
I.F. UTRs and Junctions
Polynucleotides comprising untranslated (UTR) sequences and intron/exon junctions are also within the scope of the invention. UTR sequences include introns and 5' or 3' untranslated regions ( 5' UTRs or 3' UTRs) . Portions of the sequences shown in SEQ TABLES 1 AND 2 can comprise UTRs and introns or intron/exon junctions.
These portions of SDFs, especially UTRs, can have regulatory functions related to, for example, translation rate and mRNA stability. Thus, these portions of SDFs can be isolated for use as elements of gene constructs for expression of polynucleotides encoding desired polypeptides.
Introns of genomic DNA segments might also have regulatory functions. Sometimes promoter elements, especially transcription enhancer or suppressor elements, are found within introns. Also, elements related to stability of heteronuclear RNA and efficiency of transport to the cytoplasm for translation can be found in intron elements. Thus, these segments can also find use as elements of expression vectors intended for use to transform plants.
Just as with promoters, introns and UTR sequences and intron/exon junctions can vary from those shown in SEQ TABLES
1 AND 2. Such changes from those sequences preferably will not affect the regulatory activity of the UTRs or intron or intron/exon junction sequences on expression, transcription, or translation. However, in some instances, down-regulation of such activity may be desired to modulate traits or phenotypic or in vi tro activity.
I.G. Coding Sequences
Isolated polynucleotides of the invention can include coding sequences that encode polypeptides comprising an amino acid sequence encoded by a sequences in SEQ TABLES 1 AND 2 or an amino acid sequence presented in SEQ TABLES 1 AND 2. A nucleotide sequence "encodes" a polypeptide if a cell
(or a cell free in vi tro system) expressing that nucleotide sequence produces a polypeptide having the recited amino acid sequence when the nucleotide sequence is transcribed and the primary transcript is subsequently processed and translated by a host cell (or a cell free in vi tro system) harboring the nucleic acid. Thus, an isolated nucleic acid that "encodes" a particular amino acid sequence can be a genomic sequence comprising exons and introns or a cDNA sequence that represents the product of splicing thereof. An isolated nucleic acid "encoding an amino acid sequence" also encompasses heteronuclear RNA, which contains sequences that are spliced out during expression, and mRNA, which lacks those sequences. Coding sequences can be constructed using chemical synthesis techniques or by isolating coding sequences or by modifying such synthesized or isolated coding sequences as described above. In addition to encoding the polypeptide sequences of SEQ
TABLES 1 AND 2, which are native to corn or Arabidopsis, the isolated polynucleotides can be variant polynucleotides that encode mutants, fragments, and fusions of those native proteins. Such polypeptides are described below in part II. In variant polynucleotides generally, the number of substitutions, deletions or insertions is preferably less than 20%, more preferably less than 15%; even more preferably less than 10%, 5%, 3% or 1% of the number of nucleotides comprising a particularly exemplified sequence. It is generally expected that non-degenerate nucleotide sequence changes that result in 1 to 10, more preferably 1 to 5 and most preferably 1 to 3 amino acid insertions, deletions or substitutions will not greatly affect the function of an encoded polypeptide. The most preferred embodiments are those wherein 1 to 20, preferably 1 to 10, most preferably 1 to 5 nucleotides are added to, deleted from and/or substituted in the sequences specifically disclosed in SEQ TABLES 1 AND 2.
Insertions or deletions in polynucleotides intended to be used for encoding a polypeptide should preserve the reading frame. This consideration is not so important in instances when the polynucleotide is intended to be used as a hybridization probe.
II . Polypeptides
Polypeptides within the scope of the invention include both native proteins as well as mutants, fragments, and fusions thereof. Polypeptides of the invention are those encoded by any of the six reading frames of sequences shown in SEQ TABLES 1 AND 2, preferably encoded by the three frames reading in the 5' to 3' direction of the sequences as shown.
Native polypeptides include the proteins encoded by the sequences shown in SEQ TABLES 1 AND 2. Such native polypeptides include those encoded by allelic variants.
Variants, including mutants, will exhibit at least 80% sequence identity to those native polypeptides of SEQ TABLES 1
AND 2. Sequence identity is used for polypeptides as defined above for polynucleotides. More preferably, the variants will exhibit at least 85% sequence identity; even more preferably, at least 90% sequence identity; more preferably at least 95%, 96%, 97%, 98%, or 99% sequence identity. "Fragments" of polypeptide or "portions" of polypeptides will exhibit similar degrees of identity to the relevant portions of the native polypeptide. Fusions will exhibit similar degrees of identity in that portion of the fusion represented by the variant of the native peptide.
Furthermore, variants will exhibit at least one of the functional properties of the native protein. Such properties include, without limitation, protein interaction, DNA interaction, biological activity, immunological activity, receptor binding, signal transduction, transcription activity, growth factor activity, secondary structure, three-dimensional structure, etc. As to properties related to in vitro or in vivo activities, the variants preferably exhibit at least 60% of the activity of the native protein; more preferably at least 70%, even more preferably at least 80%, 85%, 90% or 95% of at least one activity of the native protein.
A type of mutant of the native polypeptides comprises amino acid substitutions. "Conservative substitutions" are preferred to maintain the function or activity of the polypeptide. Such substitutions include conservation of charge, polarity, hydrophobicity, size, etc. For example, one or more amino acid residues within the sequence can be substituted with another amino acid of similar polarity that acts as a functional equivalent, for example providing a hydrogen bond in an enzymatic catalysis. Substitutes for an amino acid within an exemplified sequence are preferably made among the members of the class to which the amino acid belongs.
For example, the nonpolar (hydrophobic) amino acids include alanine, leucine, isoleucine, valine, proline, phenylalanine, tryptophan and methionine. The polar neutral amino acids include glycine, serine, threonine, cysteine, tyrosine, asparagine, and glutamine. The positively charged (basic) amino acids include arginine, lysine and histidine. The negatively charged (acidic) amino acids include aspartic acid and glutamic acid.
Within the scope of sequence identity described above, a polypeptide of the invention may have additional individual amino acids or amino acid sequences inserted into the polypeptide in the middle thereof and/or at the N-terminal and/or C-terminal ends thereof. Likewise, some of the- amino acids or amino acid sequences may be deleted from the polypeptide.
Antibodies
Isolated polypeptides can be utilized to produce antibodies. Polypeptides of the invention can generally be used, for example, as antigens for raising antibodies by known techniques. The resulting antibodies are useful as reagents for determining the distribution of the antigen protein within the tissues of a plant or within a cell of a plant. The antibodies are also useful for examining the expression level of proteins in various tissues, for example in a wild-type plant or following genetic manipulation of a plant, by methods such as Western blotting.
Antibodies of the present invention, both polyclonal and monoclonal, may be prepared by conventional methods. In general, the polypeptides of the invention are first used to immunize a suitable animal, such as a mouse, rat, rabbit, or goat. Rabbits and goats are preferred for the preparation of polyclonal sera due to the volume of serum obtainable, and the availability of labeled anti-rabbit and anti-goat antibodies as detection reagents. Immunization is generally performed by mixing or emulsifying the protein in saline, preferably in an adjuvant such as Freund' s complete adjuvant, and injecting the mixture or emulsion parenterally (generally subcutaneously or intramuscularly). A dose of 50-200 μg/injection is typically sufficient. Immunization is generally boosted 2-6 weeks later with one or more injections of the protein in saline, preferably using Freund' s incomplete adjuvant. One may alternatively generate antibodies by in vi tro immunization using methods known in the art, which for the purposes of this invention is considered equivalent to in vivo immunization.
Polyclonal antisera is obtained by bleeding the immunized animal into a glass or plastic container, incubating the blood at 25°C for one hour, followed by incubating the blood at 4°C for 2-18 hours. The serum is recovered by centrifugation (e.g., l,000xg for 10 minutes). About 20-50 ml per bleed may be obtained from rabbits.
Monoclonal antibodies are prepared using the method of Kohler and Milstein, Nature 256: 495 (1975), or modification thereof. Typically, a mouse or rat is immunized as described above. However, rather than bleeding the animal to extract serum, the spleen (and optinally several large lymph nodes) is removed and dissociated into single cells. If desired, the spleen cells can be screened (after removal of nonspecifically adherent cells) by applying a cell suspension to a plate, or well, coated with the protein antigen. B-cells expressing membrane-bound immunoglobulin specific for the antigen bind to the plate, and are not rinsed away with the rest of the suspension. Resulting B-cells, or all dissociated spleen cells, are then induced to fuse with myeloma cells to form hybridomas, and are cultured in a selective medium (e.g., hypoxanthine, aminopterin, thymidine medium, "HAT"). The resulting hybridomas are plated by limiting dilution, and are assayed for the production of antibodies which bind specifically to the immunizing antigen (and which do not bind to unrelated antigens) . The selected Mab-secreting hybridomas are then cultured either in vi tro ( e . g. , in tissue culture bottles or hollow fiber reactors), or in vivo (as ascites in mice) .
Other methods for sustaining antibody-producing B-cell clones, such as by EBV transformation, are known.
If desired, the antibodies (whether polyclonal or monoclonal) may be labeled using conventional techniques. Suitable labels include fluorophores, chromophores, radioactive atoms (particularly 32P and 125I) , electron-dense reagents, enzymes, and ligands having specific binding partners. Enzymes are typically detected by ther activity. For example, horseradish peroxidase is usually detected by its ability to convert 3, 3' , 5, 5' -tetramethylbenzidine (TNB) to a blue pigment, quantifiable with a spectrophotometer . "Specific binding partner" refers to a protein capable of binding a ligand molcule with high specificity, as for example in the case of an antigen and a monoclonal antibody specific therefor. Other specific binding partners include biotin and avidin or streptavidin, IgG and protein A, and the numerous receptor- ligand couples known in the art. It should be understood that the above description is not meant to categorize the various labels into distinct modes. For example, 125I may serve as a radioactive label or as an electron-dense reagent. HRP may serve as an enzyme or as an antigen for a Mab. Further one may combine various labels for desired effect. For example, Mabs and avidin also require labels in the practice of this invention: thus, one might label a Mab with biotin, and detect its presence with avidin labeled with 125I, or with an anti- biotin Mab labeled with HRP. Other permutations and possibilities will be readily apparent to those of ordinary skill in the art, and are considered as equivalents within the scope of the instant invention.
In Vitro Applications of Polypeptides
Some polypeptides of the invention will have enzymatic activities that are useful in vi tro . For example, the soybean trypsin inhibitor (Kunitz) family is one of the numerous families of proteinase inhibitors. It comprises plant proteins which have inhibitory activity against serine proteinases from the trypsin and subtilisin families, thiol proteinases and aspartic proteinases. Thus, these peptides find in vi tro use in protein purification protocols and perhaps in therapeutic settings requiring topical application of protease inhibitors.
Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (ALAD) catalyzes the second step in the biosynthesis of heme, the condensation of two molecules of 5-aminolevulinate to form porphobilinogen. Thus, ALAD proteins can be used as catalysts in synthesis of heme derivatives. Enzymes of biosynthetic pathways generally can be used as catalysts for in vi tro synthesis of the compounds representing products of the pathway. Polypeptides encoded by SDFs of the invention can be engineered to provide purification reagents to identify and purify additional polypeptides that bind to them. This allows one to identify proteins that function as multimers or elucidate signal transduction or metabolic pathways. In the case of DNA binding proteins, the polypeptide can be used in a similar manner to identify the DNA determinants of specific binding (S. Pierrou et al., Anal . Biochem . 229:99 (1995), S. Chusacultanachai et al., J. Biol . Chem . 274:23591 (1999), Q.
Lin et al., J. Biol . Chem . 272:27274 (1997)).
II.A. MUTANTS, FRAGMENTS, AND FUSIONS
Generally, mutants, fragments, or fusions of the polypeptides encoded by the maximum length seuqence (MLS) can exhibit at least one of the activities of the identified domains and/or related polypeptides described in Sections (C) and (D) of REF TABLES 1 and 2 corresponding to the MLS of interest .
II. A. (1) Mutants
A type of mutant of the native polypeptides comprises amino acid substitutions. "Conservative substitutions", described above (see II.), are preferred to maintain the function or activity of the polypeptide. polypeptide. Such substitutions include conservation of charge, polarity, hydrophobicity, size, etc. For example, one or more amino acid residues within the sequence can be substituted with another amino acid of similar polarity that acts as a functional equivalent, for example providing a hydrogen bond in an enzymatic catalysis. Substitutes for an amino acid within an exemplified sequence are preferably made among the members of the class to which the amino acid belongs. For example, the nonpolar (hydrophobic) amino acids include alanine, leucine, isoleucine, valine, proline, phenylalanine, tryptophan and methionine. The polar neutral amino acids include glycine, serine, threonine, cysteine, tyrosine, asparagine, and glutamine. The positively charged (basic) amino acids include arginine, lysine and histidine. The negatively charged (acidic) amino acids include aspartic acid and glutamic acid.
Within the scope of sequence identity described above, a polypeptide of the invention may have additional individual amino acids or amino acid sequences inserted into the polypeptide in the middle thereof and/or at the N-terminal and/or C-terminal ends thereof. Likewise, some of the amino acids or amino acid sequences may be deleted from the polypeptide. Amino acid substitutions may also be made in the sequences; conservative substitutions being preferred.
One preferred class of mutants are those that comprise (1) the domain of a MLS encoded polypeptide and/or
(2) residues conserved between the MLS encoded polypeptide and related polypeptides of the MLS. For this class of mutants, the MLS encoded polypeptide sequence is changed by insertion, deletion, or substitution at positions flanking the domain and/or conserved residues.
Another class of mutants includes those that comprise a MLS encoded polypeptide sequence that is changed in the domain or conserved residues by a conservative substitution.
Yet another class of mutants includes those that lack one of the in vi tro activities, or structural features of the MLS encoded polypeptides. One example is dominant negative mutants. Such a mutant may comprise an MLS encoded polypeptide sequence with non-conservative changes in a particular domain or group of conserved residues.
II. . (2) FRAGMENTS Fragments of particular interest are those that comprise a domain identified for a polypeptide encoded by an MLS of the instant invention and mutants thereof. Also, fragments that comprise at least one region of residues conserved between an MLS encoded polypeptide and its related polypeptides are of great interest. Fragments are sometimes useful as dominant negative mutations.
II.A. (3) FUSIONS Of interest are chimeras comprising (1) a fragment of the MLS encoded polypeptide or mutants thereof of interest and (2) a fragment of a polypeptide comprising the same domain. For example, an AP2 helix encoded by a MLS of the invention fused to second AP2 helix from ANT protein, which comprises two AP2 helices. The present invention also encompasses fusions of MLS encoded polypeptides, mutants, or fragments thereof fused with related proteins or fragments thereof. DEFINITION OF DOMAINS
The polypeptides of the invention may possess identifying domains as shown in REF TABLES 1 and 2. Domains are fingerprints or signatures that can be used to characterize protein families and/or motifs. Such fingerprints or signatures can comprise conserved (1) primary sequence, (2) secondary structure, and/or (3) three- dimensional conformation. Generally, each domain has been associated with either a family of proteins or a motif. Typically, these families and/or motifs have been correlated with specific in-vi tro and/or in-vivo activities. A domain can be any length, including the entirety of the sequence of a protein. Detailed descriptions of the domains, associated families and motifs, and correlated activities of the polypeptides of the instant invention are described below. Usually, the polypeptides with designated domain (s) can exhibit at least one activity that is exhibited by any polypeptide that comprises the same domain (s).
Specific domains within the MLS encoded polypeptides are indicated by the reference REF TABLES 1 and 2. In addition, the domains within the MLS encoded polypeptide can be defined by the region that exhibits at least 70% sequence identity with the consensus sequences listed in the detailed description below of each of the domains. The majority of the protein domain descriptions given below are obtained from Prosite,
(http//www. expasy. ch/prosite/) , and Pfam,
(http//pfam. wustl . edu/browse. shtml) .
1. (AAA) AAA-protein family signature
A large family of ATPases has been described [1 to 5] whose key feature is that they share a conserved region of about
220 amino acids that contains anATP-binding site. This family is now called AAA, for 'A'TPases 'A'ssociated with diverse cellular ' A1 ctivities . The proteins that belong to this family either contain one or two AAA domains. Proteins containing two AAA domains:
- Mammalian and drosophila NSF (N-ethylmaleimide-sensitive fusion protein) and the fungal homolog, SEC18. These proteins are involved in intracellular transport between the endoplasmic reticulum and Golgi, as well as between different Golgi cisternae.
- Mammalian transitional endoplasmic reticulum ATPase (previously known as p97 or VCP) which is involved in the transfer of membranes from the endoplasmic reticulum to the golgi apparatus. This protein forms a ring-shaped homooligomer composed of six subunits. The yeast homolog is CDC48 and it may play a role in spindle pole proliferation. - Yeast protein PAS1, essential for peroxisome assembly and the related protein PAS1 from Pichia pastoris.
- Yeast protein AFG2.
- Sulfolobus acidocaldarius protein SAV and Halobacterium salinarium cdcH which may be part of a transduction pathway connecting light to cell division.
Proteins containing a single AAA domain:
- Escherichia coli and other bacteria ftsH (or hflB) protein. FtsH is an ATP-dependent zinc metallopeptidase that seems to degrade the heat-shock sigma-32 factor. It is an integral membrane protein with a large cytoplasmic C-terminal domain that contain both the AAA and the protease domains . - Yeast protein YMEl, a protein important for maintaining the integrity of the mitochondrial compartment. YMEl is also a zinc-dependent protease.
- Yeast protein AFG3 (or YTA10) . This protein also seems to contain a AAA domain followed by a zinc-dependent protease domain.
Subunits from the regulatory complex of the 26S proteasome [6] which is involved in the ATP-dependent degradation of ubiquitinated proteins: a) Mammalian subunit 4 and homologs in other higher eukaryotes, in yeast (gene YTA5) and fission yeast (gene mts2) . b) Mammalian subunit 6 (TBP7) and homologs in other higher eukaryotes and in yeast (gene YTA2) . c) Mammalian subunit 7 (MSS1) and homologs in other higher eukaryotes and in yeast (gene CIM5 or YTA3) . d) Mammalian subunit 8 (P45) and homologs in other higher eukaryotes and in yeast (SUG1 or CIM3 or TBY1) and fission yeast (gene letl) . Other probable subunits such as human TBP1 which seems to influences HIV gene expression by interacting with the virus tat transactivator protein and yeast YTA1 and YTA6.
Yeast protein BCS1, a mitochondrial protein essential for the expression of the Rieske iron-sulfur protein. - Yeast protein MSP1, a protein involved in intramitochondrial sorting of proteins. Yeast protein PAS8, and the corresponding proteins PAS5 from Pichia pastoris and PAY4 from Yarrowia lipolytica. - Mouse protein SKD1 and its fission yeast homolog (SpAC2G11.06) .
Caenorhabditis elegans meiotic spindle formation protein mei-1. Yeast protein SAP1. - Yeast protein YTA7.
Mycobacterium leprae hypothetical protein A2126A.
It is proposed that, in general, the AAA domains in these proteins act as ATP- dependent protein clamps [5] . In addition to the ATP-binding 'A' and 'B' motifs, which are located in the N-terminal half of this domain, there is a highly conserved region located in the central part of the domain which was used to develop a signature pattern.
Consensus pattern: [LIVMT] -x- [LIVMT] - [LIVMF] -x- [GATMC] - [ST] - [NS] -x (4 ) - [LIVM] - D-x-A- [LIFA] -x-R
[1] Froehlich K.-U., Fries H.W., Ruediger M., Erdmann R. ,
Botstein D., Mecke D. J. Cell Biol. 114:443-453(1991). [2] Erdmann R. , Wiebel F.F., Flessau A., Rytka J. , Beyer A.,
Froehlich K.-U., Kunau W.-H. Cell 64:499-510 (1991) .
[3] Peters J.-M., Walsh M.J., Franke W.W. EMBO J. 9:1757-
1767 (1990) .
[4] Kunau W.-H., Beyer A., Goette K., Marzioch M., Saidowsky J., Skaletz-Rorowski A., Wiebel F.F. Biochimie 75:209-
224 (1993) .
[5] Confalonieri F., Duguet M. BioEssays 17 : 639-650 (1995) . [
6] Hilt W., Wolf D.H. Trends Biochem. Sci. 21:96-102(1996).
2. Aminotransferases class-IV signature
Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [1,2] into subfamilies. One of these, called class-IV, currently consists of the following enzymes: Branched-chain amino-acid aminotransferase (EC 2.6.1.42) (transaminase B) , a bacterial (gene ilvE) and eukaryotic enzyme which catalyzes the reversible transfer of an amino group from 4-methyl-2- oxopentanoate to glutamate, to form leucine and 2- oxoglutarate.
D-alanine aminotransferase (EC 2.6.1.21) . A bacterial enzyme which catalyzes the transfer of the amino group from D-alanine (and other D-amino acids) to 2- oxoglutarate, to form pyruvate and D-aspartate.
4-amino-4-deoxychorismate (ADC) lyase (gene pabC) . A bacterial enzyme that converts ADC into 4- aminobenzoate (PABA) and pyruvate.
The above enzymes are proteins of about 270 to 415 amino-acid residues that share a few regions of sequence similarity. Surprisingly, the best-conserved region does not include the lysine residue to which the pyridoxal- phosphategroup is known to be attached, in ilvE. The region that has been selected as a signature pattern is located some
40 residues at the C-terminus side of the PlP-lysine
Consensus pattern: E-x- [STAGCI] -x (2) -N- [LIVMFAC] - [FY] - x(6, 12) - [LIVMF] -x-T- x ( 6, 8 ) - [LIVM] -x- [GS] - [LIVM] -x- [KR] -
[1] Green J.M., Merkel W.K., Nichols B.P. J. Bacteriol.
174:5317-5323 (1992) .
[2] Bairoch A. Unpublished observations (1992) .
3. Bacterial mutT domain signature
The bacterial mutT protein is involved in the GO system [1] responsible for removing an oxidatively damaged form of guanine (8-hydroxyguanine or7 , 8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite to dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions . MutT specifically degrades 8-oxo-dGTP to the monophosphate with the concomitant release of pyrophosphate. MutT is a small protein of about 12 to 15 Kd. It has been shown [2,3] that a region of about 40 amino acid residues, which is found in the
N-terminal part of mutT, can also be found in a variety of other prokaryotic, viral, and eukaryotic proteins. These proteins are:
Streptomyces pneumoniae mutX.
A mutT homolog from plasmid pSAM2 of Streptomyces ambofaciens .
Bartonella bacilliformis invasion protein A (gene invA) .
Escherichia coli dATP pyrophosphohydrolase .
Protein D250 from African swine fever viruses.
Proteins D9 and D10 from a variety of poxviruses.
Mammalian 7 , 8-dihydro-8-oxoguanine triphosphatase (EC 3.1.6.-) [4].
Mammalian diadenosine 5 ' , 5 ' ' ' -Pi, P4-tetraphosphate asymmetrical hydrolase (Ap4Aase) (EC 3.6.1.17) [5], which cleaves A-5'-PPPP-5'A to yield AMP and ATP.
A protein encoded on the antisense RNA of the basic fibroblast growth factor gene in higher vertebrates.
Yeast protein YSA1.
Escherichia coli hypothetical protein yfaO.
Escherichia coli hypothetical protein ygdU and HI0901, the corresponding Haemophilus influenzae protein. - Escherichia coli hypothetical protein yjaD and HI0432, the corresponding Haemophilus influenzae protein.
Escherichia coli hypothetical protein yrfE.
Bacillus subtilis hypothetical protein yqkG.
Bacillus subtilis hypothetical protein yzgD. - Yeast hypothetical protein YGL067w.
It is proposed [2] that the conserved domain could be involved in the active center of a family of pyrophosphate- releasing NTPases. As a signature pattern the core region of the domain was selected; it contains four conserved glutamate residues .
Consensus pattern : G-x ( 5 ) -E-x ( 4 ) - [ STAGC ] - [LIVMAC ] -x-R-E- [LIVMFT ] -x-E-E-
[ 1 ] Michaels M . L . , Miller J . H . J . Bacteriol . 174 : 6321-
6325 ( 1992 ) .
[2] Koonin E.V. Nucleic Acids Res. 21:4847-4847(1993). [3] Mejean V., Salles C, Bullions M.J., Bessman M.J.,
Claverys J.-P. Mol. Microbiol. 11:323-330(1994).
[4] Sakumi K., Furuichi M., Tsuzuki T., Kakuma T., Kawabata
S., Maki H., Sekiguchi M. J. Biol. Chem. 268:23524-
23530 (1993) . [5] Thorne N.M.H., Hankin S., Wilkinson M.C., Nunez C,
Barraclough R. , McLennan A.G. Biochem. J. 311:717-721(1995).
4. Cystatin domain
This is a very diverse family. Attempts to define separate subfamilies have failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. Cathelicidins are related to this family but have not been included. Number of members: 147 Inhibitors of cysteine proteases [1,2,3], which are found in the tissues and body fluids of animals, in the larva of the worm Onchocerca volvulus [4], as well as in plants, can be grouped into three distinct but related families:
Type 1 cystatins (or stefins) , molecules of about 100 amino acid residues with neither disulfide bonds nor carbohydrate groups.
Type 2 cystatins, molecules of about 115 amino acid residues which contain one or two disulfide loops near their C-terminus. Kininogens, which are multifunctional plasma glycoproteins .
They are the precursor of the active peptide bradykinin and play a role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII.
They are also inhibitors of cysteine proteases. Structurally, kininogens are made of three contiguous type-2 cystatin domains, followed by an additional domain (of variable length) which contains the sequence of bradykinin. The first of the three cystatin domains seems to have lost its inhibitory activity.
In all these inhibitors, there is a conserved region of five residues which has been proposed to be important for the binding to the cysteine proteases. The consensus pattern starts one residue before this conserved region.
-Consensus pattern: [GΞTEQKRV] -Q- [LIVT] - [VAF] - [SAGQ] -G-x- [LIVMNK] -x (2) - [LIVMFY] -x- [LIVMFYA] - [DENQKRHSIV]
[1] Barrett A.J. Trends Bioche . Sci. 12:193-196(1987).
[2] Rawlings N.D., Barrett A.J. J. Mol. Evol . 30:60-71(1990).
[3] Turk V., Bode W. FEBS Lett. 285:213-219(1991).
[4] Lustigman S., Brotman B., Huima T., Prince A.M. Mol.
Biochem. Parasitol. 45:65-76(1991).
5. Dehydrins signatures
A number of proteins are produced by plants that experience water-stress. Water-stress takes place when the water available to a plant falls below a critical level. The plant hormone abscisic acid (ABA) appears to modulate the response of plant to water-stress. Proteins that are expressed during water-stress are called dehydrins [1,2] or LEA group 2 proteins [3] . The proteins that belong to this family are listed below. - Arabidopsis thaliana XERO 1, XERO 2 (LTI30), RAB18,
ERD10 (LTI45) ERD14 and COR47.
- Barley dehydrins B8, B9, B17, and B18.
- Cotton LEA protein D-ll. - Craterostigma plantagineum dessication-related proteins A and B.
- Maize dehydrin M3 (RAB-17) .
- Pea dehydrins DHN1, DHN2, and DHN3. Radish LEA protein. - Rice proteins RAB 16B, 16C, 16D, RAB21, and RAB25.
- Tomato TAS14.
Wheat dehydrin RAB 15 and cold-shock protein cor410, cs66 and csl20.
Dehydrins share a number of structural features. One of the most notable features is the presence, in their central region, of a continuous run of five to nine serines followed by a cluster of charged residues. Such a region has been found in all known dehydrins so far with the exception of pea dehydrins. A second conserved feature is the presence of two copies of alysine-rich octapeptide; the first copy is located just after the cluster of charged residues that follows the poly-serine region and the second copy is found at the C-terminal extremity. Signature patterns for both regions were derived.
Consensus pattern: S (5) - [DE] -x- [DE] -G-x (1, 2) -G-x (0, 1) - [KR] (4 Consensus pattern: [KR] - [LIM] -K- [DE] -K- [LIM] -P-G-
[1] Close T.J., Kortt A. A. , Chandler P.M. Plant Mol. Biol. 13:95-108 (1989) .
[2] Robertson M., Chandler P.M. Plant Mol. Biol. 19:1031- 1044 (1992) . [3] Dure L. Ill, Crouch M., Harada J. , Ho T.-H. D., Mundy J. ,
Quatrano R. , Thomas T., Sung Z.R. Plant Mol. Biol. 12:475-
486(1989) .
6. D-isomer specific 2-hydroxyacid dehydrogenases (2 Hacid DH)
This Pfam covers the Formate dehydrogenase, D-glycerate dehydrogenase and D-lactate dehydrogenase families in SCOP. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown [1,2,3,4] to be functionally and structurally related. These enzymes are listed below.
D-lactate dehydrogenase (EC 1.1.1.28), a bacterial enzyme which catalyzes the reduction of D-lactate to pyruvate.
- D-glycerate dehydrogenase (EC 1.1.1.29) (NADH- dependent hydroxypyruvate reductase) , a plant leaf peroxisomal enzyme that catalyzes the reduction of hydroxypyruvate to glycerate. This reaction is part of the glycolate pathway of photorespiration.
D-glycerate dehydrogenase from the bacteria Hyphomicrobium methylovorum and Methylobacterium extorquens .
3-phosphoglycerate dehydrogenase (EC 1.1.1.95), a bacterial enzyme that catalyzes the oxidation of D-3- phosphoglycerate to 3-phosphohydroxypyruvate . This reaction is the first committed step in the 1 phosphorylated ' pathway of serine biosynthesis. Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-) (gene pdxB) , a bacterial enzyme involved in the biosynthesis of pyridoxine (vitamin B6) . D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-) (D- hicDH) , a bacterial enzyme that catalyzes the reversible and stereospecific interconversion between 2-ketocarboxylic acids and D-2-hydroxy-carboxylic acids .
Formate dehydrogenase (EC 1.2.1.2) (FDH) from the bacteria Pseudomonas sp. 101 and various fungi [5] . - Vancomycin resistance protein vanH from Enterococcus faecium; this protein is a D-specific alpha-keto acid dehydrogenase involved in the formation of a peptidoglycan which does not terminate by D-alanine thus preventing vancomycin binding. - Escherichia coli hypothetical protein ycdW.
Escherichia coli hypothetical protein yiaE.
Haemophilus influenzae hypothetical protein HI1556.
Yeast hypothetical protein YER081w.
Yeast hypothetical protein YIL074w. All these enzymes have similar enzymatic activities and are structurally related. Three of the most conserved regions of these proteins have been selected to develop patterns. The first pattern is based on a glycine-rich region located in the central section of these enzymes; this region probably corresponds to the NAD-binding domain. The two other patterns contain a number of conserved charged residues, some of which may play a role in the catalytic mechanism.
-Consensus pattern: [LIVMA] - [AG] - [ IVT] - [LIVMFY] - [AG] -x-G- [NHKRQGSAC] - [LIV] -G-x (13, 14) - [LIVfMT] -x (2) - [FYwCTH] - [DNSTK]
-Consensus pattern: [LIVMFYWA] - [LIVFYWC] -x (2 ) - [SAC] - [DNQHR] -
[IVFA] - [LIVF] -x- [LIVF] - [HNI ] -x-P-x ( 4 ) - [STN] -x (2) - [LIVMF] -x-
[GSDN]
-Consensus pattern: [LMFATC] - [KPQ] -x- [GSTDN] -x- [LIVMFYWR] - [LIVMFYW] (2)-N-x-[STAGC]-R-[GP]-x-[LIVH]-[LIVMC]-[DNV]
[1] Grant G.A. Biochem. Biophys . Res. Commun. 165:1371- 1374 (1989) . [2] Kochhar S., Hunziker P., Leong-Morgenthaler P.M.,
Hottinger H. Biochem. Biophys. Res. Commun. 184:60-66(1992).
[3] Ohta T., Taguchi H. J. Biol. Chem. 266:12588-12594(1991).
[4] Goldberg J.D., Yoshida T., Brick P. J. Mol. Biol. 236:1123-1140 (1994) .
[5] Popov V.O., La zin V.S. Biochem. J. 301:625-643(1994).
7. dnaJ domains signatures and profile
The prokaryotic heat shock protein dnaJ interacts with the chaperone hsp70-like dnaK protein [1]. Structurally, the dnaJ protein consists of an N- terminal conserved domain (called 'J' domain) of about 70 amino acids, a glycine-rich region ('G' domain') of about 30 residues, a central domain containing four repeats of a CXXCXGXG motif ('CRR' domain) and a C-terminal region of 120 to 170 residues. Such a structure is shown in the following schematic representation:
+ i N-terminal I I Gly-R I I CXXCXGXG | C- terminal | + +-+ + + + +
It has been shown [2] that the 'J' domain as well as the 'CRR' domain are also found in other prokaryotic and eukaryotic proteins which are listed below. a) Proteins containing both a 'J' and a 'CRR' domain: - Yeast protein MAS5/YDJ1 which seems to be involved in mitochondrial protein import.
Yeast protein MDJ1, involved in mitochondrial biogenesis and protein folding.
Yeast protein SCJ1, involved in protein sorting. - Yeast protein XDJl .
Plants dnaJ homologs (from leek and cucumber) .
Human HDJ2, a dnaJ homolog of unknown function.
Yeast hypothetical protein YNL077w. b) Proteins containing a 'J' domain without a 'CRR' domain: Rhizobium fredii nolC, a protein involved in cultivar- specific nodulation of soybean.
Escherichia coli cbpA [3], a protein that binds curved
DNA. - Yeast protein SEC63/NPL1, important for protein assembly into the endoplasmic reticulum and the nucleus .
Yeast protein SIS1, required for nuclear migration during mitosis. - Yeast protein CAJ1.
Yeast hypothetical protein YFR041c.
Yeast hypothetical protein YIR004w.
Yeast hypothetical protein YJL162c.
Plasmodium falciparum ring-infected erythrocyte surface antigen (RESA) . RESA, whose function is not known, is associated with the membrane skeleton of newly invaded erythrocytes .
- Human HDJl .
Human HSJ1, a neuronal protein. - Drosophila cysteine-string protein (csp) .
A signature pattern for the 'J' domain was developed, based on conserved positions in the C-terminal half of this domain. A pattern for the 'CRR' domain, based on the first two copies of that motif was also developed. A profile for the 'J' domain was also developed.
Consensus pattern: [FY] -x (2) - [LIVMA] -x (3) - [FYWHNT] - [DENQSA] - x-L-x-[DN]-x(3) - [KR]-x(2) -[FYI]-
Consensus pattern: C- [DEGSTHKR] -x-C-x-G-x- [GK] - [AGSDM] -x (2) - [GSNKR]-x(4, 6) -C- x (2, 3) -C-x-G-x-G-
[1] Cyr D.M., Langer T., Douglas M.G. Trends Biochem. Sci. 19:176-181 (1994) . [2] Bork P., Sander C, Valencia A., Bukau B. Trends Biochem.
Sci. 17:129-129(1992) .
[3] Ueguchi C, Kaneda M., Yamada H., Mizuno T. Proc. Natl.
Acad. Sci. U.S.A. 91:1054-1058(1994).
8. Domain of unknown function
9. Gamma-thionins family signature
The following small plant proteins are evolutionary related:
Gamma-thionins from wheat endosperm (gamma- purothionins) and barley (gamma- hordothionins) which are toxic to animal cells and inhibit protein synthesis in cell free systems [1]. - A flower-specific thionin (FST) from tobacco [2]. Antifungal proteins (AFP) from the seeds of Brassicaceae species such as radish, mustard, turnip and Arabidopsis thaliana [3] .
Inhibitors of insect alpha-amylases from sorghum [4] . - Probable protease inhibitor P322 from potato. A germination-related protein from cowpea [5] . Anther-specific protein SF18 from sunflower [6]. SF18 is a protein that contains a gamma-thionin domain at its N-terminus and a proline-rich C- terminal domain. - Soybean sulfur-rich protein SE60 [7] .
Vicia faba antibacterial peptides fabatin-1 and -2. In their mature form, these proteins generally consist of about 45 to 50amino-acid residues. As shown in the following schematic representation, these peptides contain eight conserved cysteines involved in disulfide bonds.
+ + I + + I I I 1 I xxCxxxxxxxxxxCxxxxxCxxxCxxxxxxxxxCxxxxxxCxCxxxC
* * * * * * * * * * * * * * * * * * * I * * * I I I _) I I- i _| + ' C: conserved cysteine involved in a disulfide bond.
'*': position of the pattern.
Consensus pattern: [KRG] -x-C-x (3) - [SV] - (2) - [FYWH] -x- [GF] -x- C-x (5) -C-x (3) -C [The four C's are involved in disulfide bonds] -
[1] Bruix M., Jimenez M.A., Santoro J., Gonzalez C, Colilla
F.J., Mendez E., Rico M. Biochemistry 32:715-724(1993). [2] Gu Q., Kawata E.E., Morse M.-J., Wu H.-M., Cheung A.Y.
Mol. Gen. Genet. 234:89-96(1992).
[3] Terras F.R.G., Torrekens S., van Leuven F., Osborn R.W.,
Vanderleyden J. , Cammue B.P.A., Broekaert W.F. FEBS Lett.
316:233-240 (1993) . [4] Bloch C. Jr., Richardson M. FEBS Lett. 279:101-104(1991).
[5] Ishibashi N., Yamauchi D., Miniamikawa T. Plant Mol.
Biol. 15:59-64 (1990) .
[7] Choi Y., Choi Y.D., Lee J.S. Plant Physiol. 101:699-
700 (1993) .
10. haloacid dehalogenase-like hydrolase
This family is structurally different from the alpha/ beta hydrolase family (abhydrolase) . This family includes L- 2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment, between residues 16 and 96 of Swiss : P24069. The rest of the fold is composed of the core alpha/beta domain. [1] Hisano T, Hata Y, Fujii T, Liu JQ, Kurihara T, Esaki N, Soda K, J Biol Chem 1996; 271:20322-20330.
11. Helix-turn-helix (HTH3) This large family of DNA binding helix-turn helix proteins includes Cro Swiss: P03036 and CI Swiss: P03034.
12. Heme-binding domain in cytochrome b5 and oxidoreductases (heme_l)
Cytochrome b5 is a membrane-bound hemo protein which acts as an electron carrier for several membrane-bound oxygenases [1]. There are two homologous forms of b5, one found in microsomes and one found in the outer membrane of mitochondria. Two conserved histidine residues serve as axial ligands for the heme group. The structure of a number of oxidoreductases consists of the juxtaposition of a heme- binding domain homologous to that of b5 and either a flavodehydrogenase or a molybdopterin domain. These enzymes are:
Lactate dehydrogenase (EC 1.1.2.3) [2], an enzyme that consists of a flavodehydrogenase domain and a heme- binding domain called cytochrome b2. Nitrate reductase (EC 1.6.6.1) , a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria [3,4]. Consists of a molybdopterin domain (see <PDOC00484>) , a heme-binding domain called cytochrome b557, as well as a cytochrome reductase domain. - Sulfite oxidase (EC 1.8.3.1) [5], which catalyzes the terminal reaction in the oxidative degradation of sulfur-containing amino acids. Also consists of a molybdopterin domain and a heme-binding domain. This family of proteins also includes: - TU-36B, a Drosophila muscle protein of unknown function [6] .
Fission yeast hypothetical protein SpAClF12.10c. Yeast hypothetical protein YMR073c. Yeast hypothetical protein YMR272c. A segment was used which includes the first of the two histidine heme ligands, as a signature pattern for the heme- binding domain of cytochrome b5 family.
Consensus pattern: [FY] - [LIVMK] -x (2 ) -H-P- [GA] -G [H is a heme axial ligand] -
[1] Ozols J. Biochim. Biophys . Acta 997:121-130(1989).
[2] Guiard B. EMBO J. 4:3265-3272(1985). [3] Calza R. , Huttner E., Vincentz M., Rouze P., Galangau F. ,
Vaucheret H., Cherel I., Meyer C, Kronenberger J. , Caboche
M. Mol. Gen. Genet. 209:552-562(1987).
[4] Crawford N.M., Smith M., Bellissimo D., Davis R.W. Proc.
Natl. Acad. Sci. U.S.A. 85:5006-5010(1988). [5] Guiard B., Lederer F. Eur. J. Biochem. 100:441-453(1979).
[6] Levin R.J., Boychuk P.L., Croniger CM., Kazzaz J.A.,
Rozek C.E. Nucleic Acids Res. 17:6349-6367(1989).
13. KH domain KH motifs probably bind RNA directly. Auto antibodies to
Nova, a KH domain protein, cause paraneoplastic opsoclonus ataxia .
[1] Burd CG, Dreyfuss G, Science 1994;265:615-621.
[2] Musco G, Stier G, Joseph C, Castiglione Morelli MA, Nilges M, Gibson TJ, Pastore A, Cell 1996;85:237-245.
14. MAPEG family (aka: FLAP/GST2/LTC4S family signature)
The following mammalian proteins are evolutionary related [1] : - Leukotriene C4 synthase (EC 2.5.1.37) (gene LTC4S) , an enzyme that catalyzes the production of LTC4 from LTA4. Microsomal glutathione S-transferase II (EC 2.5.1.18)
(GST-II) (gene GST2), an enzyme that can also produces
LTC4 fron LTA4.
5-lipoxygenase activating protein (gene FLAP) , a protein that seems to be required for the activation of 5-lipoxygenase.
These are proteins of 150 to 160 residues that contain three transmembrane segments. As a signature pattern, a conserved region between the first and second transmembrane domains was selected.
Consensus patternc: G-x (3) -F-E-R-V- [FY] -x-A- [NQ] -x-N-C
[1] Jakobsson P.-J., Mancini J.A. , Ford-Hutchinson A.W. J. Biol. Chem. 271:22203-22210(1996).
15. Pathogenesis-related protein Bet v I family signature
A number of plant proteins, which all seem to be involved in pathogen defense response, a__ structurally related [1,2,3]. These proteins are:
Bet v I, the major pollen allergen from white birch.
Bet v I is the main cause of type I allergic reactions in Europe, North America and USSR.
Aln g I, the major pollen allergen from alder. - Api G I, the major allergen from celery.
Car b I, the major pollen allergen from hornbeam.
Cor a I, the major pollen allergen from hazel.
Mai d I, the major pollen allergen from apple.
Asparagus wound-induced protein AoPRl. - Kidney bean pathogenesis-related proteins 1 and 2.
Parsley pathogenesis-related proteins PR1-1 and PR1-3.
Pea disease resistance response proteins pI49, pI176 and DRRG49-C.
Pea abscisic acid-responsive proteins ABR17 and ABR18. Potato pathogenesis-related proteins STH-2 and STH-21.
Soybean stress-induced protein SAM22.
These proteins are thought to be intracellularly located. They contain from 155 to 160 amino acid residues. As a signature pattern, a conserved region located in the third quarter of these proteins has been selected
Consensus pattern: G-x (2) - [LIVMF] -x (4 ) -E-x (2 ) - [CSTAEN] - x(8, 9)-[GND]-G-[GS]- [CS] -x (2 ) -K-x ( 4 ) - [FY] -
[1] Breiteneder H., Pettenburger K., Bito A., Valenta R. ,
Kraft D., Rumpold H., Scheiner 0., Breitenbach M. EMBO J.
8:1935-1938 (1989) .
[2] Crowell D., John M.E., Russell D. , Amasino R.M. Plant
Mol. Biol. 18:459-466(1992). [3] Warner S.A.J., Scott R. , Draper J. Plant Mol. Biol.
19:555-561(1992) .
16. Photosystem I psaG / psaK (PSI PSAK) proteins signature Photosystem I (PSI) [1] is an integral membrane protein complex that uses light energy to mediate electron transfer from plastocyanin to ferredoxin. It is found in the chloroplasts of plants and cyanobacteria . PSI is composed of at least 14 different subunits, two of which PSI-G (gene psaG) and PSI-K (gene psaK) are small hydrophobic proteins of about 7 to 9 Kd and evolutionary related [2] . Both seem to contain two transmembrane regions. Cyanobacteria seem to encode only for PSI-K.
As a signature pattern, the best-conserved region was selected which seems to correspond to the second transmembrane region.
-Consensus pattern: [GT] -F-x- [LIVM] -x- [DEA] -x (2) - [GA] -x- [GTA] - [SA] -x-G-H-x- [LIVM] - [GA] [1] Golbeck J.H. Biochim. Biophys. Acta 895:167-204(1987).
[2] Kjaerulff S., Andersen B., Nielsen V.S., Moller B.L.,
Okkels J.S. J. Biol. Chem. 268:18912-18916(1993).
17. Plant lipid transfer protein family signature (LTP) Plant cells contain proteins, called lipid transfer proteins (LTP) [1,2,3], which are able to facilitate the transfer of phospholipids and other lipidsacross membranes. These proteins, whose subcellular location is not yet known, could play a major role in membrane biogenesis by conveying phospholipids such as waxes or cutin from their site of biosynthesis to membranes unable to form these lipids. Plant LTP's are proteins of about 9 Kd (90 amino acids) which contain eight conserved cysteine residues all involved in disulfide bridges, as shown in the following schematic representation.
+ + i + + i i i i i
xCxxxxCxxxxxxCCxxxxxxxxCxCxxxxxxxxxxxCxxxxxxCxx I I I I + I + I + +
'C: conserved cysteine involved in a disulfide bond. '*': position of the pattern.
Consensus pattern: [LIVM] - [PA] -x (2 ) -C-x- [LIVM] -x- [LIVM] -x- [LIVMFY]-x-[LIVM]- [ST] -x ( 3 ) - [DN] -C-x (2 ) - [LIVM] [The two C's are involved in disulfide bonds]
[1] Wirtz K.W.A. Annu . Rev. Biochem. 60:73-99(1991). [2] Arondel V., Kader J.C. Experientia 46:579-585(1990). [3] Ohlrogge J.B., Browse J. , Somerville C.R. Biochim. Biophys. Acta 1082:1-26(1991).
18. Ribosomal protein S7e signature A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities [1]. One of these families consists of:
Mammalian S7. - Xenopus S8.
Insect S7.
Yeast probable ribosomal protein S7 (N2212) .
Fission yeast probable ribosomal protein S7
(SpAC18G6.13c) . These proteins have about 200 amino acids. A highly conserved stretch of 14 residues which is located in the central section and which is rich in charged residues was selected as a signature pattern.
Consensus pattern: [KR] -L-x-R-E-L-E-K-K-F- [SAP] -x- [KR] -H
[1] Salazar C.E., Mills-Hamm D.M., Kumar V., Collins F.H. Nucleic Acids Res. 21:4147-41 7(1993).
19. Ribosomal protein L34 signature
Ribosomal protein L34 is one of the proteins from the large subunit of the prokaryotic ribosome. It is a small basic protein of 44 to 51 amino-acid residues [1] . L34 belongs to a family of ribosomal proteins which, on the basis of sequence similarities, groups: - Eubacterial L34. - Red algal chloroplast L34. - Cyanelle L34. A conserved region that corresponds to the N-terminal half of L34 has been selected as a signature pattern. -Consensus pattern: K- [RG] -T- [FYWL] - [EQS] -x (5) - [KRHS] -x (4 , 5) - G-F-x(2)-R
[ 1] Old I.G., Margarita D., Saint Girons I. Nucleic Acids Res. 20:6097-6097(1992). 20. Ribosomal protein L6 signatures
Ribosomal protein L6 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L6 is known to bind directly to the 23S rRNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3,4], groups: -
Eubacterial L6.
Algal chloroplast L6. - Cyanelle L6.
- Archaebacterial L6.
Marchantia polymorpha mitochondrial L6. Yeast mitochondrial YmLδ (gene MRPL6) . Mammalian L9. - Drosophila L9.
- Plants L9.
- Yeast L9 (YL11) .
While all the above proteins are evolutionary related it is very difficult to derive a pattern that will find them all. Two patterns were therefore created, the first to detect eubacterial, cyanelle and mitochondrial L6, the second to detect archaebacterial L6 as well as eukaryotic L9. -Consensus pattern: [PS] - [DENS] -x-Y-K- [GA] -K-G- [LIVM] -Consensus pattern: Q-x (3) - [LIVM] -x (2) - [KR] -x (2) -R-x-F-x-D-G- [LIVM]-Y-[LIVM]-x(2)-[KR]
[1] Suzuki K., Olvera J. , Wool I.G. Gene 93:297-300(1990). [2] Schwank S., Harrer R. , Schueller H.-J., Schweizer E. Curr. Genet. 24:136-140(1993). [3] Golden B.L., Ramakrishnan V., White S.W. EMBO J. 12:4901- 4908 (1993) .
[ 4] Otaka E., Hashimoto T., Mizuta K., Suzuki K. Protein Seq. Data Anal. 5:301-313(1993). 21. Ribosomal protein S14p/S29e (Ribosomal protein S14 signature)
Ribosomal protein S14 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S14 is known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of 16S rRNA at the A site. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:
- Eubacterial S14. - Algal and plant chloroplast S14.
- Cyanelle S14.
Archaebacterial Methanococcus vannielii S14. Plant mitochondrial S14. Yeast mitochondrial MRP2. - Mammalian S29.
- Yeast YS29A/B.
S14 is a protein of 53 to 115 amino-acid residues. Our signature pattern is based on the few conserved positions located in the center of these proteins.
Consensus pattern: [RP] -x (0, 1) -C-x ( 11, 12) - [LIVMF] -x- [LIVMF] - [SC] ~[RG]-x(3) -[RN]
[1] Chan Y.-L., Suzuki K. , Olvera J. , Wool I.G. Nucleic Acids Res. 21:649-655(1993) .
[2] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300 (1993) .
22. Ribosomal protein S16 signature Ribosomal protein S16 is one of the proteins from the small ribosomal subunit. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: Eubacterial S16. Algal and plant chloroplast S16.
- Cyanelle S16.
Neurospora crassa mitochondrial S24 (cyt-21) .
S16 is a protein of about 100 amino-acid residues. A conserved region located in the N-terminal extremity of these proteins has been selected as a signature pattern.
Consensus pattern: [LIVMT] -x- [LIVM] - [KR] -L- [STAK] -R-x-G- [AKR]
[1] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300(1993) .
23. Ribosomal protein S21 signature
Ribosomal protein S21 is one of the proteins from the small ribosomal subunit. So far S21 has only been found in eubacteria. It is a protein of 55 to 70 amino-acid residues. A conserved region in the N-terminal section of the protein has been selected as a signature pattern.
Consensus pattern: [DE] -x-A- [LIY] - [KR] -R-F-K- [KR] -x (3) - [KR]
24. Universal stress protein family (Usp)
By a wide range of stress conditions members of the Usp family are predicted to be related to the MADS-box proteins transcript fact and bind to DNA [2] . Number of members: 39
[1] Expression and role of the universal stress protein, UspA, of Escherichia coli during growth arrest. Nystrom T, Neidhardt FC; Mol Microbiol 1994; 11:537-544. [2] Sequence analysis of eukaryotic developmental proteins: ancient and novel domains. Mushegian AR, Koonin EV; Genetics 1996; 144:817-828. III . Methods of Modulating Polypeptide Production
Within the scope of invention are chimeric gene constructs wherein the promoter and the structural coding sequence and/or other regulatory sequences within said constructs are heterologous to each other. "Heterologous sequences" are those that are not operatively linked or are not contiguous to each other in nature. For example, a promoter from corn is considered heterologous to an Arabidopsis coding region sequence. Also, a promoter from a gene encoding a growth factor from corn is considered heterologous to a sequence encoding the corn receptor for the growth factor. Regulatory element sequences, such as UTRs or 3' end termination sequences that do not originate in nature from the same gene as the coding sequence originates from, are considered heterologous to said coding sequence. On the other hand, elements operatively linked in nature are not heterologous. Thus, the promoter and coding portion of a corn gene expressing an amino acid transporter are not heterologous to each other. Such chimeric polynucleotides are of particular interest for modulating gene expression in a host cell upon transformation of said cell with said chimeric polynucleotide.
Also within the scope of the invention are DNA molecules, whereof at least a part or portion of these DNA molecules are presented in SEQ TABLES 1 AND 2 of the present application, and wherein the structural coding sequence is under the control of its own promoter and/or its own regulatory elements. Such DNA molecules are useful for transforming the genome of a host cell or an organism regenerated from said host cell. Typically, such polynucleotides, whether chimeric or not, are "exogenous to" the genome of an individual host cell or the organism regenerated fro^m said host cell, such as a plant cell, respectively for a plant, when initially or subsequently introduced into said host cell or organism, by any means other than by a sexual cross. Examples of means by which this can be accomplished are described below, and include Agrobacterium- mediated transformation (of dicots - e.g. Salomon et al . EMBO
J. 3:141 (1984); Herrera-Estrella et al. EMBO J. 2:987 (1983); A.C. Vergunst et al, Nucleic Acids Res . 26:11, 2729 (1998); of monocots, representative papers are those by Escudero et al.,
Plant J. 1_0:355 (1996), Ishida et al., Nature Biotechnology
14:745 (1996), May et al., Bio/Technology 13:486 (1995)), biolistic methods (Armaleo et al., Current Genetics 17 : 97 1990)), electroporation, in planta techniques, and the like. Such a plant containing the exogenous nucleic acid is referred to here as an Ri generation transgenic plant. Transgenic plants which arise from a sexual cross with another parent line or by selfing are "descendants or the progeny" of a R_ plant and are generally called Fn plants or Sn plants, respectively, n meaning the number of generations.
The SDFs prepared as described herein can be used to prepare expression cassettes useful in a number of techniques for suppressing or enhancing expression.
III. A. Suppression
Expression cassettes of the invention can be used to suppress expression of endogenous genes which comprise the SDF sequence. Inhibiting expression can be useful, for instance, to tailor the ripening characteristics of a fruit (Oeller et al., Science 254:437 (1991)) or to influence seed size__(WO98/07842) or or to provoke cell ablation (Mariani et al., Nature 357: 384-387 (1992).
As described above, a number of methods can be used to inhibit gene expression in plants, such as antisense, ribozyme, introduction of "exogenous" genes into a host cell, insertion of a polynucleotide sequence into the coding sequence and/or the promoter of the endogenous gene of interest, and the like. III.A.l. Antisense
An expression cassette as described above can be transformed into host cell or plant to produce an antisense strand of RNA. In plant cells, it has been suggested that antisense RNA inhibits gene expression by preventing the accumulation of mRNA which encodes the enzyme of interest, see, e.g., Sheehy et al., Proc . Na t . Acad. Sci . USA, 85:8805 (1988), and Hiatt et al., U.S. Patent No. 4,801,340.
III.A.2. Ribozymes Similarly, ribozyme constructs can be transformed into a plant to cleave mRNA and down-regulate translation.
III.A.3. Co-Suppression
Another method of suppression is by introducing an exogenous copy of the gene to be suppressed. Introduction of expression cassettes in which a nucleic acid is configured in the sense orientation with respect to the promoter has been shown to be an effective means by which to block the transcription of target genes. A detailed description of this method is described above.
III. A.4. Insertion of Sequences into the Gene to be Modulated Yet another means of suppressing gene expression is to insert a polynucleotide into the gene of interest to disrupt transcription or translation of the gene. Homologous recombination couldeeft be used to target a polynucleotide insert to a gene using the Cre-Lox system (A.C. Vergunst et al., Nucleic Acids Res . 26:2729 (1998), A.C. Vergunst et al., Plant Mol . Biol . 38:393 (1998), H. Albert et al., Plant J. 7:649 (1995)). In addition, random insertion of polynucleotides into a host cell genome can also be used to disrupt the gene of interest. Azpiroz-Leehan et al., Trends in Genetics 13 : 152
(1997). In this method, screening for clones from a library containing random insertions is preferred for identifying those that have polynucleotides inserted into the gene of interest.
Such screening can be performed using probes and/or primers described above based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto. The screening can also be performed by selecting clones or Ri plants having a desired phenotype.
III. A.5. Promoter Modulation
Inactivation of the promoter that drives a gene of interest can modulate transcription and translation, and therefore expression. For example, triple helices can be formed using oligonucleotides based on sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto. The oligonucleotide can be delivered to the host cell can bind to the promoter in the genome to form a triple helix and prevent transcription.
Additionally, a vector capable of producing the oligonucleotide can be inserted into the host cell to deliver the oligonucleotide.
III. A.6. Expression of Mutants An alternative method for inhibiting gene function is through the use of dominant negative mutations. Dominant negative mutations produce a mutant polypeptide which is capable of competing with the native polypeptide, but which does not produce the native result. Consequently, over expression of these mutations can titrate out an undesired activity of the native protein. For example, the inactive dominant-negative mutant may bind to the same receptor as the native protein, preventing the native protein from activating a signal transduction pathway. Alternatively, the dominant- negative mutant can be an inactive enzyme still capable of binding to the same substrate as the native protein. Dominant-negative mutants also can act upon the native protein itself to prevent activity. For example, the native protein may be active only as a homo-multimer or as one subunit of a hetero-multimer . Incorporation of an inactive subunit into the multimer with native subunit (s) can inhibit activity.
Thus, gene function can be modulated by insertion of an expression construct encoding a dominant-negative mutant into a host cell of interest.
III.B. Enhanced Expression Enhanced expression of a gene of interest in a host cell can be accomplished by either (1) insertion of an exogenous gene; or (2) promoter modulation.
III.B.1. Insertion of an Exogenous Gene
Insertion of an expression construct encoding an exogenous gene can boost the number of gene copies expressed in a host cell.
Such expression constructs can comprise genes that either encode the native protein that is of interest or that encode a variant that exhibits enhanced activity as compared to the native protein. Such genes encoding proteins of interest can be constructed from the sequences from SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequence thereto.
Such an exogenous gene can include either a constitutive promoter permitting expression in any cell in a host organism or a promoter that directs expression only in particular cells or times during a host cell life cycle or in response to environmental stimuli. III.B.2. Promoter Modulation
Some promoters require binding of a regulatory protein to be activated. Other promoters may need a protein that signals a promoter binding protein to expose a polymerase binding site. In either case, over-expression of such proteins can be used to enhance expression of a gene of interest by increasing the activation time of the promoter.
Such regulatory proteins are encoded by some of the sequences in SEQ TABLES 1 AND 2, fragments thereof, and substantially similar sequences thereto.
Coding sequences for these proteins can be constructed as described above.
In some cases, duplication of enhancer elements or insertion of exogenous enhancer elements will increase expression of a desired gene from a particular promoter. The useful enhancer elements can be portions of one or more of the SDFs of SEQ TABLES 1 AND 2.
IV. Gene Constructs and Vector Construction To use isolated SDFs of the present invention or a combination of them or parts and/or mutants and/or fusions of said SDFs in the above techniques, recombinant DNA vectors which comprise said SDFs and are suitable for transformation of cells, such as plant cells, are usually prepared. The vector backbone can be any of those typical in the art such as plasmids, viruses, artificial chromosomes, BACs, YACs and PACs and vectors of the sort described by **.
Typically, a vector will comprise the exogenous gene, which in its turn comprises an SDF of the present invention to be introduced into the genome of a host cell, and which gene may be an antisense construct, a ribozyme construct, or a structural coding sequence with any desired transcriptional and/or translational regulatory sequences, such as promoters and 3' end termination sequences. Vectors of the invention can also include origins of replication, markers, homologous sequences, introns, etc.
A DNA sequence coding for the desired polypeptide, for example a cDNA sequence encoding a full length protein, will preferably be combined with transcriptional and translational initiation regulatory sequences which will direct the transcription of the sequence from the gene in the intended tissues of the transformed plant. For example, for over-expression, a plant promoter fragment may be employed that will direct expression of the gene in all tissues of a regenerated plant. Such promoters are referred to herein as "constitutive" promoters and are active under most environmental conditions and states of development or cell differentiation. Examples of constitutive promoters include the cauliflower mosaic virus (CaMV) 35S transcription initiation region, the 1' or 2' promoter derived from T-DNA of Agrobacterium tumefaciens , and other transcription initiation regions from various plant genes known to those of skill. Alternatively, the plant promoter may direct expression of an SDF of the invention in a specific tissue (tissue-specific promoters) or may be otherwise under more precise environmental control (inducible promoters) . Examples of tissue-specific promoters under developmental control include promoters that initiate transcription only in certain tissues, such as root, ovule, fruit, seeds, or flowers. The promoter from a LEC1 gene, described in copending application U.S. Ser. No. 09/103,478, is particularly useful for directing gene expression so that a desired gene product is located in embryos or seeds. Other suitable promoters include those from genes encoding storage proteins or the lipid body membrane protein, oleosin. A few root-specific promoters are noted above. Examples of environmental conditions that may affect transcription by inducible promoters include anaerobic conditions, elevated temperature, or the presence of light.
If proper polypeptide expression is desired, a polyadenylation region at the 3 ' -end of the coding region should be included. The polyadenylation region can be derived from the natural gene, from a variety of other plant genes, or from T-DNA.
The vector comprising the sequences (e. g. , promoters or coding regions) from genes of the invention will typically comprise a marker gene that confers a selectable phenotype on plant cells. For example, the marker may encode biocide resistance, particularly antibiotic resistance, such as resistance to kanamycin, G418, bleomycin, hygromycin, or herbicide resistance, such as resistance to chlorosulfuron or phosphinotricin.
IV.A. Coding Sequences
Generally, the sequence in the transformation vector and to be introduced into the genome of the host cell does not need to be absolutely identical to an SDF of the present invention. Also, it is not necessary for it to be full length, relative to either the primary transcription product or fully processed mRNA. Use of sequences shorter than full-length may be preferred to avoid concurrent production of some plants that are overexpressors. Furthermore, the introduced sequence need not have the same intron or exon pattern as a native gene. Also, heterologous non-coding segments can be incorporated into the coding sequence without changing the desired amino acid sequence of the polypeptide to be produced.
IV. B. Promoters As explained above, introducing an exogenous SDF from the same species or an orthologous SDF from another species can modulate the expression of a native gene corresponding to that SDF of interest. Such an SDF construct can be under the control of either a constitutive promoter ( e . g. , the promoter of the 35S gene of the cauliflower mosaic virus or the promotor of the gene encoding the cowpea trypsin inhibitor) or a highly regulated inducible promoter (e.g., a copper inducible promoter) . The promoter of interest can initially be either endogenous or heterologous to the species in question. When re-introduced into the genome of said species, such promoter becomes "exogenous" to said species. The promoter-SDF construct can be made using standard recombinant DNA techniques (Sambrook et al. 1989) and can be introduced to the species of interest by Λgrojacterium-mediated transformation or by other means of transformation (e.g., particle gun bombardment) as referenced above. Over- expression of an SDF transgene can lead to co-suppression of the homologous gene thereby creating some alterations in the phenotypes of the transformed species as demonstrated by similar analysis of the chalcone synthase gene (Napoli et al., Plan t Cell 2:279 (1990) and van der Krol et al., Plant Cell 2:291 (1990)). If an SDF is found to encode a protein with desirable characteristics, its over-expression can be controlled so that its accumulation can be manipulated in an organ- or tissue-specific manner utilizing a promoter having such specificity. Likewise, if the promoter of an SDF (or an SDF that includes a promoter) is found to be tissue-specific or developmentally regulated, such a promoter can be utilized to drive the expression of a specific gene of interest (e.g., seed storage protein or root-specific protein) . Thus, the level of accumulation of a particular protein can be manipulated or its spatial localization in an organ- or tissue- specific manner can be altered. IV. C Signal Peptides
In some cases it may be desirable for the protein encoded by an introduced exogenous or orthologous SDF to be targeted (1) to a particular organelle, (2) to interact with a particular molecule or (3) for secretion outside of the cell harboring the introduced SDF. This will be accomplished using a signal peptide.
Signal peptides direct protein targeting, are involved in ligand-receptor interactions and act in cell to cell communication. Many proteins, especially soluble proteins, contain a signal peptide that targets the protein to one of several different intracellular compartments. In plants, these compartments include, but are not limited to, the endoplasmic reticulum (ER) , mitochondria, plastids (such as chloroplasts) , the vacuole, the Golgi apparatus, protein storage vessicles (PSV) and, in general, membranes . Some signal peptide sequences are conserved, such as the Asn-Pro- Ile-Arg amino acid motif found in the N-terminal propeptide signal that targets proteins to the vacuole (Marty (1999) The Plant Cell 11: 587-599). Other signal peptides do not have a consensus sequence per se, but are largely composed of hydrophobic amino acids, such as those signal peptides targeting proteins to the ER (Vitale and Denecke (1999) The Plant Cell 11: 615-628). Still others do not appear to contain either a consensus sequence or an identified common secondary sequence, for instance the chloroplast stromal targeting signal peptides (Keegstra and Cline (1999) The Plant Cell 11: 557-570). Furthermore, some targeting peptides are bipartite, directing proteins first to an organelle and then to a membrane within the organelle (e.g. within the thylakoid lumen of the chloroplast; see Keegstra and Cline (1999) The Plant Cell 11: 557-570). In addition to the diversity in sequence and secondary structure, placement of the signal peptide is also varied. Proteins destined for the vacuole, for example, have targeting signal peptides found at the N-terminus, at the C-terminus and at a surface location in mature, folded proteins.
Signal peptides also serve as ligands for some receptors. Perhaps the best known example of this is the interaction of the ER targeting signal peptide with the signal recognition particle (SRP) . Here, the SRP binds to the signal peptide, halting translation, and the resulting
SRP complex then binds to docking proteins located on the surface of the ER, prompting the transfer of the protein into the ER.
These characteristics of signal proteins can be used to more tightly control the expression of introduced SDFs. In particular, associating the appropriate signal sequence with a specific SDF can allow sequestering of the protein in specific organelles (plastids, as an example) , secretion outside of the cell, targeting interaction with particular receptors, etc. Hence, the inclusion of signal proteins in constructs involving the SDFs of the invention increases the range of manipulation of SDF expression. To carry this out, constructs are made with the nucleotide sequence of a known signal peptide immediately 5' to the initiation of the coding region of an SDF so that the signal peptide is translated in frame with the coding region and immediately precedes it. The nucleotide sequence of the signal peptide can be isolated from characterized genes using common molecular biological techniques or can be synthesized in vitro.
V. Transformation Techniques
A wide range of techniques for inserting exogenous polynucleotides are known for a number of host cells, including, without limitation, bacterial, yeast, mammalian, insect and plant cells. Techniques for transforming a wide variety of higher plant species are well known and described in the technical and scientific literature. See, e.g. Weising et al., Ann . Rev.
Genet . 22:421 (1988); and Christou, Euphytica, v. 85, n.1-3: 13- 27, (1995).
DNA constructs of the invention may be introduced into the genome of the desired plant host by a variety of conventional techniques. For example, the DNA construct may be introduced directly into the genomic DNA of the plant cell using techniques such as electroporation and microinjection of plant cell protoplasts, or the DNA constructs can be introduced directly to plant tissue using ballistic methods, such as DNA particle bombardment. Alternatively, the DNA constructs may be combined with suitable T-DNA flanking regions and introduced into a conventional Agrobacterium tumefaciens host vector. The virulence functions of the Agrobacterium tumefaciens host will direct the insertion of the construct and adjacent marker into the plant cell DNA when the cell is infected by the bacteria
(Vergunst et al . , Nucl . Acids . Res . 26:2729 (1998) (site- directed integration using a Cre-Lox recombinase system) ;
McCormac et al., Mol . Biotechnol . 8:199 (1997); Hamilton, Gene
2JD0:107 (1997)); Salomon et al. EMBO J. 3:141 (1984); Herrera-
Estrella et al. EMBO J. 2:987 (1983).
Microinjection techniques are known in the art and well described in the scientific and patent literature. The introduction of DNA constructs using polyethylene glycol precipitation is described in Paszkowski et al . EMBO J. 3:2717
(1984). Electroporation techniques are described in Fromm et al. Proc. Na tl Acad. Sci . USA 82:5824 (1985). Ballistic transformation techniques are described in Klein et al . Nature
327 : 773 (1987). Agroba cteri um tumefa ciens-mediated transformation techniques, including disarming and use of binary vectors, are well described in the scientific literature. See, for example Hamilton, CM. , Gene 200: 107 (1997); Mϋller et al . Mol . Gen . Genet . 207:171 (1987); Komari et al. Plant J. 10:165 (1996); Venkateswarlu et al.
Biotechnology 9:1103 (1991) and Gleave, AP. , Plant Mol . Biol .
20:1203 (1992); Graves and Goldman, Plant Mol . Biol . 7:34 (1986) and Gould et al., Plant Physiology 95 : 426 (1991).
Transformed plant cells which are derived by any of the above transformation techniques can be cultured to regenerate a whole plant that possesses the transformed genotype and thus the desired phenotype such as seedlessness. Such regeneration techniques rely on manipulation of certain phytohormones in a tissue culture growth medium, typically relying on a biocide and/or herbicide marker which has been introduced together with the desired nucleotide sequences. Plant regeneration from cultured protoplasts is described in Evans et al., Protoplasts Isola tion and Cul ture in "Handbook of Plant Cell Culture," pp. 124-176, MacMillan Publishing Company, New York, 1983; and Binding, Regenera tion of Plants, Plant Protoplasts, pp. 21-73, CRC Press, Boca Raton, 1988. Regeneration can also be obtained from plant callus, explants, organs, or parts thereof. Such regeneration techniques are described generally in Klee et al. Ann. Rev. of Plant Phys . 38:467 (1987). Regeneration of monocots (rice) is described by Hosoyama et al. ( Biosci . Biotechnol . Biochem . 58:1500 (1994)) and by Ghosh et al. ( J. Biotechnol . 32:1 (1994)). The nucleic acids of the invention can be used to confer desired traits on essentially any plant.
Thus, the invention has use over a broad range of plants, including species from the genera Asparagus , Atropa , Avena ,
Brassica , Ci trus, Ci trullus , Capsicum, Cucumis , Cucurbita ,
Daucus, Fragaria , Glycine, Gossypium, Helianthus , Heterocallis , Hordeum, Hyoscyamus, Lactuca , Linum, Lolium, Lycopersicon, Malus , Manihot , Majorana , Medicago, Nicotiana , Oryza , Panieum, Pannesetum, Persea , Pisum, Pyrus , Prunus , Raphanus , Secale, Senecio, Sinapis , Solanum, Sorghum , Trigonella , Tri ticum , V' tis, Vigna , and, Zea . One of skill will recognize that after the expression cassette is stably incorporated in transgenic plants and confirmed to be operable, it can be introduced into other plants by sexual crossing. Any of a number of standard breeding techniques can be used, depending upon the species to be crossed.
The particular sequences of SDFs identified are provided in the attached SEQ TABLES 1 AND 2. One of ordinary skill in the art, having this data, can obtain cloned DNA fragments, synthetic DNA fragments or polypeptides constituting desired sequences by recombinant methodology known in the art or described herein.
EXAMPLES
The invention is illustrated by way of the following examples. The invention is not limited by these examples as the scope of the invention is defined solely by the claims following.
EXAMPLE 1: SOUTHERN HYBRIDIZATIONS
The SDFs of the invention can be used in Southern hybridizations as described above. The following describes extraction of DNA from nuclei of plant cells, digestion of the nuclear DNA and separation by length, transfer of the separated fragments to membranes, preparation of probes for hybridization, hybridization and detection of the hybridized probe.
The procedures described herein can be used to isolate related polynucleotides or for diagnostic purposes. Moderate stringency hybridization conditions, as defined above, are described in the present example. These conditions result in detection of hybridization between sequences having at least 70% sequence identity. As described above, the hybridization and wash conditions can be changed to reflect the desired degree of sequence identity between probe and target sequences that can be detected.
In the following procedure, a probe for t-ke hybridization is produced from two PCR reactions using two primers from genomic sequence of Arabidopsis thaliana . As described above, the particular template for generating the probe can be any desired template.
The first PCR product is assessed to validate the size of the primer to assure it is of the expected size. Then the product of the first PCR is used as a template, with the same pair of primers used in the first PCR, in a second PCR that produces a labeled product used as the probe.
Fragments detected by hybridization, or other bands of interest, can be isolated from gels used to separate genomic DNA fragments by known methods for further purification and/or characterization.
Buffers for nuclear DNA extraction
1. 10X HB
Adjust pH to 9.5 with 10 N NaOH. It appears that there is a nuclease present in leaves. Use of pH 9.5 appears to inactivate this nuclease. . 2 M sucrose (684 g per 1000 ml)
Heat about half the final volume of water to about 50 C. Add the sucrose slowly then bring the mixture to close to final volume; stir constantly until it has dissolved. Bring the solution to volume.
3. Sarkosyl solution (lyses nuclear membranes)
1000 ml N-lauroyl sarcosine (Sarkosyl) 20.0 g
0.1 M Tris 12.1 g
0.04 M EDTA (Disodium) 14.9 g
Adjust the pH to 9.5 after all the components are dissolved and bring up to the proper volume.
4. 20% Triton X-100
80 ml Triton X-100 320 ml lxHB (w/o β-ME and PMSF)
Prepare in advance; Triton takes some time to dissolve
A. Procedure
1. Prepare IX " H" buffer (keep ice-cold during use)
1000 ml
10X HB 100 ml
2 M sucrose 250 ml a non-ionic osmoticum
Water 634 ml
Added just before use:
100 mM PMSF^ 10 ml a protease inhibitor; protects nuclear membrane proteins β-mercaptoethanol 1 ml inactivates nuclease by reducing disulfide bonds
*100 mM PMSF
(phenyl methyl sulfonyl fluoride, Sigma P-7626) (add 0.0875 g to 5 ml 100% ethanol)
Homogenize the tissue in a blender (use 300-400 ml of
IxHB per blender) . Be sure that you use 5-10 ml of HB buffer per gram of tissue. Blenders generate heat so be sure to keep the homogenate cold. It is necessary to put the blenders- in ice periodically.
Add the 20% Triton X-100 (25 ml per liter of homogenate) and gently stir on ice for 20 min. This lyses plastid, but not nuclear, membranes.
Filter the tissue suspension through several nylon filters into an ice-cold beaker. The first filtration is through a 250-micron membrane; the second is through an 85-micron membrane; the third is through a 50-micron membrane; and the fourth is through a 20-micron membrane. Use a large funnel to hold the filters. Filtration can be sped up by gently squeezing the liquid through the filters.
Centrifuge the filtrate at 1200 x g for 20 min. at 4°C to pellet the nuclei.
Discard the dark green supernatant. The pellet will have several layers to it. One is starch; it is white and gritty. The nuclei are gray and soft. In the early steps, there may be a dark green and somewhat viscous layer of chloroplasts .
Wash the pellets in about 25 ml cold H buffer (with Triton X-100) and resuspend by swirling gently and pipetting. After the pellets are resuspended.
Pellet the nuclei again at 1200 - 1300 x g. Discard the supernatant .
Repeat the wash 3-4 times until the supernatant has changed from a dark green to a pale green. This usually happens after 3 or 4 resuspensions . At this point, the pellet should be grayish white and very slippery. The Triton X-100 in these repeated steps helps to destroy the chloroplasts and mitochondria that contaminate the prep.
Resuspend the nuclei foi a final time in a total of 15 ml of H buffer and transfer the suspension to a sterile 125 ml Erlenmeyer flask.
7. Add 15 ml, dropwise, cold 2% Sarkosyl, 0.1 M Tris, 0.04 M EDTA solution (pH 9.5) while swirling gently. This lyses the nuclei. The solution will become very viscous .
8. Add 30 grams of CsCl and gently swirl at room temperature until the CsCl is in solution. The mixture will be gray, white and viscous.
9. Centrifuge the solution at 11,400 x g at 4°C for at least 30 min. The longer this spin is, the firmer the protein pellicle. 10. The result should be a clear green supernatant over a white pellet, and (perhaps) under a protein pellicle. Carefully remove the solution under the protein pellicle and above the pellet. Determine the density of the solution by weighing 1 ml of solution and add CsCl if necessary to bring to 1.57 g/ml. The solution contains dissolved solids (sucrose etc) and the refractive index alone will not be an accurate guide to CsCl concentration.
11. Add 20 μl of 10 mg/ml EtBr per ml of solution.
12. Centrifuge at 184,000 x g for 16 to 20 hours in a fixed- angle rotor.
13. Remove the dark red supernatant that is at the top of the tube with a plastic transfer pipette and discard.
Carefully remove the DNA band with another transfer pipette. The DNA band should be visible in room light; otherwise, use a long wave UV light to locate the band.
14. Extract the ethidium bromide with isopropanol saturated with water and salt. Once the solution is clear, extract at least two more times to ensure that all of the EtBr is gone. Be very gentle, as it is very easy to shear the DNA at this step. This extraction may take a while because the DNA solution tends to be very viscous. If the solution is too viscous, dilute it with TE .
15. Dialyze the DNA for at least two days against several changes (at least three times) of TE (10 mM Tris, ImM EDTA, pH 8) to remove the cesium chloride. 16. Remove the dialyzed DNA from the tubing. If the dialyzed DNA solution contains a lot of debris, centrifuge the DNA solution at least at 2500 x g for 10 min. and carefully transfer the clear supernatant to a new tube. Read the A260 concentration of the DNA.
17. Assess the quality of the DNA by agarose gel electophesis (1% agarose gel) of the DNA. Load 50 ng and 100 ng (based on the OD reading) and compare it with known and good quality DNA. Undigested lambda DNA and a lambda-Hindlll-digested DNA are good molecular weight makers .
Protocol for Digestion of Genomic DNA
Protocol :
1. The relative amounts of DNA for different crop plants that provide approximately a balanced number of genome equivalent is given in Table 3. Note that due to the size of the wheat genome, wheat DNA will be underrepresented. Lambda DNA provides a useful control for complete digestion.
2. Precipitate the DNA by adding 3 volumes of 100% ethanol. Incubate at -20°C for at least two hours. Yeast DNA can be purchased and made up at the necessary concentration, therefore no precipitation is necessary for yeast DNA.
3. Centrifuge the solution at 11,400 x g for 20 min. Decant the ethanol carefully (be careful not to disturb the pellet) . Be sure that the residual ethanol is completely removed either by vacuum desiccation or by carefully wiping the sides of the tubes with a clean tissue . 4. Resuspend the pellet in an appropriate volume of water.
Be sure the pellet is fully resuspended before proceeding to the next step. This may take about 30 min.
5. Add the appropriate volume of 10X reaction buffer provided by the manufacturer of the restrictioned-enzyme to the resuspended DNA followed by the appropriate volume of enzymes. Be sure to mix it properly by slowly swirling the tubes.
6. Set-up the lambda digestion-control for each DNA that you are digesting.
7. Incubate both the experimental and lambda digests overnight at 37 C. Spin down condensation in a microfuge before proceeding.
8. After digestion, add 2 μl of loading dye (typically 0.25% bromophenol blue, 0.25% xylene cyanol in 15% Ficoll or 30% glycerol) to the lambda-control digests and load in 1% TPE-agarose gel (TPE is 90 mM Tris- phosphate, 2 mM EDTA, pH 8) . If the lambda DNA in the lambda control digests are completely digested, proceed with the precipitation of the genomic DNA in the digests .
9. Precipitate the digested DNA by adding 3 volumes of 100% ethanol and incubating in -20°C for at least 2 hours (preferably overnight) .
EXCEPTION: Arabidopsis and yeast DNA are digested in an appropriate volume; they don't have to be precipitated. 10. Resuspend the DNA in an appropriate volume of TE (e.g., 22 μl x 50 blots = 1100 μl ) and an appropriate volume of 10X loading dye (e.g., 2.4 μl x 50 blots = 120 μl) . Be careful in pipetting the loading dye - it is viscous. Be sure you are pipetting the correct volume.
Table 3
Some guide points in digesting genomic DNA.
Protocol for Southern Blot Analysis
The digested DNA samples are electrophoresed in 1% agarose gels in lx TPE buffer. Low voltage; overnight separations are preferred. The gels are stained with EtBr and photographed.
1. For blotting the gels, first incubate the gel in 0.25 N HC1 (with gentle shaking) for about 15 min. 2. Then briefly rinse with water. The DNA is denatured by 2 incubations. Incubate (with shaking) in 0.5 M NaOH in 1.5 M NaCl for 15 min.
3. The gel is then briefly rinsed in water and neutralized by incubating twice (with shaking) in 1.5 M Tris pH 7.5 in 1.5 M NaCl for 15 min.
4. A nylon membrane is prepared by soaking it in water for at least 5 min, then in 6X SSC for at least 15 min. before use. (20x SSC is 175.3 g NaCl, 88.2 g sodium citrate per liter, adjusted to pH 7.0.)
5. The nylon membrane is placed on top of the gel and all bubbles in between are removed. The DNA is blotted from the gel to the membrane using an absorbent medium, such as paper toweling and 6x SCC buffer. After the transfer, the membrane may be lightly brushed with a gloved hand to remove any agarose sticking to the surface .
6. The DNA is then fixed to the membrane by UV crosslinking and baking at 80°C. The membrane is stored at 4°C until use.
B. Protocol for PCR Amplification of Genomic Fragments in Arabidopsis
Amplification procedures:
1. Mix the following in a 0.20 ml PCR tube or 96-well PCR plate:
Final Amount or
Volume Stock Cone.
2. The template DNA is amplified using a Perkin Elmer 9700 PCR machine:
1) 94°C for 10 min. followed by
21 21 11
5 cycles: 5 cycles: 25 cycles:
94 °C - 30 sec 94 °C - 30 sec 94 °C - 30 sec
62 °C - 30 sec 58 °C - 30 sec 53 °C - 30 sec
72 °C - 3 min 72 °C - 3 min 72 °C - 3 min
5) 72 C for 7 min. Then the reactions are stopped by chilling to 4°C.
Arabidopsis DNA is used in the present experiment, but the procedure is a general one. The procedure can be adapted to a multi-well format if necessary.
Quantification and Dilution of PCR Products:
1. The product of the PCR is analyzed by electrophoresis in a 1% agarose gel. A linearized plasmid DNA can be used as a quantification standard (usually at 50, 100, 200, and 400 ng) . These will be used as references to approximate the amount of PCR products. Hindlll-digested Lambda DNA is useful as a molecular weight marker. The gel can be run fairly quickly; e.g., at 100 volts. The standard gel is examined to determine that the size of the PCR products is consistent with the expected size and if there are significant extra bands or smeary products in the PCR reactions.
2. The amounts of PCR products can be estimated on the basis of the plasmid standard.
3. For the small number of reactions that produce extraneous bands, a small amount of DNA from bands with the correct size can be isolated by dipping a sterile 10-μl tip into the band while viewing though a UV Transilluminator. The small amount of agarose gel (with the DNA fragment) is used in the labeling reaction.
C. Protocol for PCR-DIG-Labeling of DNA
Solutions : Reagents in PCR reactions (diluted PCR products, 10X PCR Buffer, 50 mM MgCl2, 5 U/μl Platinum Taq Polymerase, and the primers)
10X dNTP + DIG-11-dUTP [1:5]: (2 mM dATP, 2 mM dCTP, 2 mM dGTP, 1.65 mM dTTP, 0.35 mM DIG-11-dUTP) 10X dNTP + DIG-11-dUTP [1:10]: (2 mM dATP, 2 mM dCTP, 2 mM dGTP, 1.81 mM dTTP, 0.19 mM DIG-11-dUTP)
10X dNTP + DIG-11-dUTP [1:15]: (2 mM dATP, 2 mM dCTP, 2 mM dGTP, 1.875 mM dTTP, 0.125 mM DIG-11-dUTP)
TE buffer (10 mM Tris, 1 mM EDTA, pH 8)
Maleate buffer: In 700 ml of deionized distilled water, dissolve 11.61 g maleic acid and 8.77 g NaCl. Add NaOH to adjust the pH to 7.5. Bring the volume to 1 L. Stir for 15 min. and sterilize.
10% blocking solution: In 80 ml deionized distilled water, dissolve l.lδg maleic acid. Next, add NaOH to adjust the pH to 7.5. Add 10 g of the blocking reagent powder (Boehringer Mannheim, Indianapolis, IN, Cat. no. 1096176) . Heat to 60°C while stirring to dissolve the powder. Adjust the volume to 100 ml with water. Stir and sterilize.
1% blocking solution: Dilute the 10% stock to 1% using the maleate buffer.
Buffer 3 (100 mM Tris, 100 mM NaCl, 50 mM MgCl2, pH9.5). Prepared from autoclaved solutions of IM Tris pH 9.5, 5 M NaCl, and 1 M MgCl2 in autoclaved distilled water. Procedure :
PCR reactions are performed in 25 μl volumes containing:
PCR buffer IX
MgCl2 1.5 mM
10X dNTP + DIG-11-dUTP IX (please see the note below)
Platinum Taq™ Polymerase 1 unit 10 pg probe DNA 10 pmol primer 1
Note: Use for:
10X dNTP + DIG-11-dUTP (1:5: < 1 kb
10X dNTP + DIG-11-dUTP (1:10) 1 kb to 1.8 kb 10X dNTP + DIG-11-dUTP (1:15) > 1.8 kb
2. The PCR reaction uses the following amplification cycles:
94 C for 10 min.
2L 11 il
5 cycles: 5 cycles: 25 cycles:
95°C - 30 sec 95°C - 30 sec 95°C - 30 sec
61°C - 1 min 59°C - 1 min 51°C - 1 min
73°C - 5 min 75°C - 5 min 73°C - 5 min
72 C for 8 min. The reactions are terminated by chilling to 4°C (hold) .
The products are analyzed by electrophoresis- in a 1% agarose gel, comparing to an aliquot of the unlabelled probe starting material. The amount of DIG-labeled probe is determined as follows :
Make serial dilutions of the diluted control DNA in dilution buffer (TE: 10 mM Tris and 1 mM EDTA, pH 8) as shown in the following table:
a. Serial deletions of a DIG-labeled standard DNA ranging from 100 pg to 10 pg are spotted onto a positively charged nylon membrane, marking the membrane lightly with a pencil to identify each dilution.
Serial dilutions (e.g., 1:50, 1:2500, 1:10,000) of the newly labeled DNA probe are spotted.
c. The membrane is fixed by UV crosslinking. d. The membrane is wetted with a small amount of maleate buffer and then incubated in 1% blocking solution for 15 min at room temp.
The labeled DNA is then detected using alkaline phosphatase conjugated anti-DIG antibody
(Boehringer Mannheim, Indianapolis, IN, cat. no. 1093274) and an NBT substrate according to the manufacture's instruction.
f. Spot intensities of the control and experimental dilutions are then compared to estimate the concentration of the PCR-DIG-labeled probe.
D . Prehybridization and Hybridization of Southern Blots
Solutions :
100% Formamide purchased from Gibco
20X SSC (IX = 0.15 M NaCl, 0.015 M
Na3citrate) per L: 175 g NaCl
87 . 5 g Na3citrate - 2H20
20% Sarkosyl (N-lauroyl-sarcosine)
20% SDS (sodium dodecyl sulphate)
10% Blocking Reagent: In 80 ml deionized distilled water, dissolve 1.16 g maleic acid. Next, add NaOH to adjust the pH to 7.5. Add 10 g of the blocking reagent powder. Heat to 60°C while stirring to dissolve the powder. Adjust the volume to 100 ml with water. Stir and sterilize.
Prehybridization Mix:
General Procedures:
1. Place the blot in a heat-sealable plastic bag and add an appropriate volume of prehybridization solution (30 ml/lOOcm2) at room temperature. Seal the bag with a heat sealer, avoiding bubbles as much as possible. Lay down the bags in a large plastic tray (one tray can accommodate at least 4-5 bags) . Ensure that the bags are lying flat in the tray so that the prehybridization solution is evenly distributed throughout the bag. Incubate the blot for at least 2 hours with gentle agitation using a waver shaker.
Denature DIG-labeled DNA probe by incubating for 10 min. at 98 °C using the PCR machine and immediately cool it to 4°C.
Add probe to prehybridization solution (25 ng/ml; 30 ml = 750 ng total probe) and mix well but avoid foaming. Bubbles may lead to background.
Pour off the prehybridization solution from the hybridization bags and add new prehybridization and probe solution mixture to the bags containing the membrane .
5. Incubate with gentle agitation for at least 16 hours
6. Proceed to medium stringency post-hybridization wash: Three times for 20 min. each with gentle agitation using
IX SSC, 1% SDS at 60°C.
All wash solutions must be prewarmed to 60°C. Use about 100 ml of wash solution per membrane.
To avoid background keep the membranes fully submerged to avoid drying in spots; agitate sufficiently to avoid having membranes stick to one another.
7. After the wash, proceed to immunological detection and CSPD development.
E. Procedure for Immunological Detection with CSPD
Solutions :
Buffer 1: Maleic acid buffer (0.1 M maleic acid, 0.15 M NaCl; adjusted to pH 7.5 with NaoH)
Washing buffer: Maleic acid buffer with 0.3% (v/v) Tween 20.
Blocking stock solution 10% blocking reagent in buffer 1.
Dissolve (10X concentration) : blocking reagent powder (Boehringer Mannheim, Indianapolis, IN, cat. no.
1096176) by constantly stirring on a 65°C heating block or heat in a microwave, autoclave and store at 4°C.
Buffer 2 (IX blocking solution): Dilute the stock solution 1:10 in
Buffer 1.
Detection buffer: 0.1 M Tris, 0.1 M NaCl, pH 9.5
Procedure: 1. After the post-hybridization wash the blots are briefly rinsed (1-5 min.) in the maleate washing buffer with gentle shaking.
2. Then the membranes are incubated for 30 min. in Buffer 2 with gentle shaking.
3. Anti-DIG-AP conjugate (Boehringer Mannheim,
Indianapolis, IN, cat. no. 1093274) at 75 mU/ml
(1:10,000) in Buffer 2 is used for detection. 75 ml of solution can be used for 3 blots.
4. The membrane is incubated for 30 min. in the antibody solution with gentle shaking.
5. The membrane are washed twice in washing buffer with gentle shaking. About 250 mis is used per wash for 3 blots .
6. The blots are equilibrated for 2-5 min in 60 ml detection buffer.
7. Dilute CSPD (1:200) in detection buffer. (This can be prepared ahead of time and stored in the dark at 4°C) .
The following steps must be done individually. Bags (one for detection and one for exposure) should be cut and ready before doing the following steps. . The blot is carefully removed from the detection buffer and excess liquid removed without drying the membrane. The blot is immediately placed in a bag and 1.5 ml of CSPD solution is added. The CSPD solution can be spread over the membrane. Bubbles present at the edge and on the surface of the blot should be removed by gentle rubbing. The membrane is incubated for 5 min. in CSPD solution.
9. Excess liquid is removed and the membrane is blotted briefly (DNA side up) on Whatman 3MM paper. Do not let the membrane dry completely.
10. Seal the damp membrane in a hybridization bag and incubate for 10 min at 37°C to enhance the luminescent reaction.
11. Expose for 2 hours at room temperature to X-ray film. Multiple exposures can be taken. Luminescence continues for at least 24 hours and signal intensity increases during the first hours.
Example 2 : Transformation of Carrot Cells Transformation of plant cells can be accomplished by a number of methods, as described above. Similarly, a number of plant genera can be regenerated from tissue culture following transformation. Transformation and regeneration of carrot cells as described herein is illustrative. Single cell suspension cultures of carrot (Daucus carota ) cells are established from hypocotyls of cultivar Early Nantes in B5 growth medium (O.L. Gamborg et al., Plant Physiol . 45:372 (1970)) plus 2,4-D and 15 mM CaCl2 (B5 -44 medium) by methods known in the art. The suspension cultures are subcultured by adding 10 ml of the suspension culture to 40 ml of B5-44 medium in 250 ml flasks every 7 days and are maintained in a shaker at 150 rpm at 27 °C in the dark.
The suspension culture cells are transformed with exogenous DNA as described by Z. Chen et al . Plant Mol . Bio. 3_6:163 (1998). Briefly, 4-days post-subculture cells are incubated with cell wall digestion solution containing 0.4 M sorbitol, 2% driselase, 5mM MES (2- [N-Morpholino] ethanesulfonic acid) pH 5.0 for 5 hours. The digested cells are pelleted gently at 60 xg for 5 min. and washed twice in W5 solution containing 154 mM NaCl, 5 mM KCl, 125 mM CaCl2 and 5mM glucose, pH 6.0. The protoplasts are suspended in MC solution containing 5 mM MES, 20 mM CaCl2, 0.5 M mannitol, pH 5.7 and the protoplast density is adjusted to about 4 x 106 protoplasts per ml. 15-60 μg of plasmid DNA is mixed with 0.9 ml of protoplasts. The resulting suspension is mixed with 40% polyethylene glycol (MW 8000, PEG 8000), by gentle inversion a few times at room temperature for 5 to 25 min. Protoplast culture medium known in the art is added into the PEG-DNA- protoplast mixture. Protoplasts are incubated in the culture medium for 24 hour to 5 days and cell extracts can be used for assay of transient expression of the introduced gene. Alternatively, transformed cells can be used to produce transgenic callus, which in turn can be used to produce transgenic plants, by methods known in the art. See, for example, Nomura and Komamine, Pi t . Phys . 79:988-991 (1985), Identifica tion and Isola tion of Single Cells tha t Produce Soma tic Embryos in Carrot Suspension Cul tures .
The invention being thus described, it will be apparent to one of ordinary skill in the art that various modifications of the materials and methods for practicing the invention can be made. Such modifications are to be considered within the scope of the invention as defined by the following claims.
Each of the references from the patent and periodical literature cited herein is hereby expressly incorporated in its entirety by such citation.
REF TABLE 1
Maximum Length Sequence: related to: Clone IDs: 9581
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 1
- Ceres seq_id 1007546
- Alternative transcription start site(s) located in SEQ ID NO 1:
-96,-51,25,27,29,55, 64
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 2 - Ceres seq_id 1007547
- Location of start within SEQ ID NO 1: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 2: at 32 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 1
- gi No. 3879939 - Description:
- % Identity: 45.9
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 2: from 48 to 108
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 3
- Ceres seq_id 1007548
- Location of start within SEQ ID NO 1: at 100 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 2 - gi No. 3879939
- Description:
- % Identity: 45.9
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 3: from 15 to 75
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 4
- Ceres seq_id 1007549 - Location of start within SEQ ID NO 1: at 121 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 3
- gi No. 3879939
- Description:
- % Identity: 45.9
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 4: from 8 to 68
(Ba) Polypeptide Activities: Similar to yeast membrane protein activities
Maximum Length Sequence: related to: Clone IDs: 9568 402131 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 5
- Ceres seq_id 1007583
- Alternative transcription start site(s) located in SEQ ID NO 5: 2,3,4,7,10,11,12,17,42,43,300,505
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 6
- Ceres seq_id 1007584 - Location of start within SEQ ID NO 5: at 55 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- KH domain - Location within SEQ ID NO 6: from 47 to 95 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 4
- gi No. 133940 - Description:
- % Identity: 75.1
- Alignment Length: 250
- Location of Alignment in SEQ ID NO 6: from 1 to
249
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 7
- Ceres seq_id 1007585
- Location of start within SEQ ID NO 5: at 184 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- KH domain
- Location within SEQ ID NO 7: from 4 to 52 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 5
- gi No. 133940
- Description: - % Identity: 75.1
- Alignment Length: 250
- Location of Alignment in SEQ ID NO 7: from 1 to 206 Maximum Length Sequence: related to: Clone IDs:
91769 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 8
- Ceres seq_id 1008148
- Alternative transcription start site(s) located in SEQ ID NO 8:
-19,2,3,4,5,6,7,9,10,11,12,14
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 9
- Ceres seq_id 1008149
- Location of start within SEQ ID NO 8: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 6 - gi No. 4539292
- Description:
- % Identity: 89.9
- Alignment Length: 181
- Location of Alignment in SEQ ID NO 9: from 25 to 203
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 10
- Ceres seq_id 1008150 - Location of start within SEQ ID NO 8: at 75 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 7
- gi No. 4539292 - Description:
- % Identity: 89.9
- Alignment Length: 181
- Location of Alignment in SEQ ID NO 10: from 1 to 179
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 11
- Ceres seq_id 1008151 - Location of start within SEQ ID NO 8: at 210 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 8
- gi No. 4539292
- Description:
- % Identity: 89.9
- Alignment Length: 181 - Location of Alignment in SEQ ID NO 11: from 1 to
134
(Ba) Polypeptide Activities: Similar to 40S Ribosomal protein activities, and glycine rich RNA binding protein activities.
Maximum Length Sequence: related to: Clone IDs: 8898 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 12
- Ceres seq_id 1008334 - Alternative transcription start site(s) located in SEQ ID NO 12:
-12,29,30
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 13
- Ceres seq_id 1008335
- Location of start within SEQ ID NO 12: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 9
- gi No. 3602948
- Description: - % Identity: 43.7
- Alignment Length: 71 - Location of Alignment in SEQ ID NO 13: from 178 to 248
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 14
- Ceres seq_id 1008336
- Location of start within SEQ ID NO 12: at 59 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 14: at 22 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 10 - gi No. 3602948
- Description:
- % Identity: 43.7
- Alignment Length: 71
- Location of Alignment in SEQ ID NO 14: from 159 to 229
(Ba) Polypeptide Activities: Plant specific gene, Chloroplast specific gene. Maximum Length Sequence: related to: Clone IDs: 8286 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 15
- Ceres seq_id 1008701
- Alternative transcription start site(s) located in SEQ ID NO 15:
-6, 2, 3, 5, 6, 7, 18, 24, 25, 28, 31, 33, 35, 37, 42, 50
>) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 16
- Ceres seq_id 1008702
- Location of start within SEQ ID NO 15: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 11 - gi No. 1083282
- Description:
- % Identity: 41.4
- Alignment Length: 106
- Location of Alignment in SEQ ID NO 16: from 23 to 121 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 17
- Ceres seq_id 1008703
- Location of start within SEQ ID NO 15: at 67 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 12 - gi No. 1083282
- Description:
- % Identity: 41.4
- Alignment Length: 106
- Location of Alignment in SEQ ID NO 17: from 1 to 99
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 18
- Ceres seq_id 1008704 - Location of start within SEQ ID NO 15: at 2 nt .
(Ba) Polypeptide Activities: Similar to cytochrome C oxidase activities .
Maximum Length Sequence: related to: Clone IDs: 7792 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 19
- Ceres seq_id 1009003
- Alternative transcription start site(s) located in SEQ ID NO 19: 2,374
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 20
- Ceres seq_id 1009004 - Location of start within SEQ ID NO 19: at 48 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 13
- gi No. 3582320
- Description:
- % Identity: 32.6
- Alignment Length: 44 - Location of Alignment in SEQ ID NO 20: from 51 to
93 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 21
- Ceres seq_id 1009005 - Location of start within SEQ ID NO 19: at 57 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 14
- gi No. 3582320
- Description:
- % Identity: 32.6
- Alignment Length: 44 - Location of Alignment in SEQ ID NO 21: from 48 to
90
(Ba) Polypeptide Activities: Similar to Ring-H2 Zinc Finger Protein activities.
Maximum Length Sequence: related to: Clone IDs: 7337
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 22
- Ceres seq_id 1009345
- Alternative transcription start site(s) located in SEQ ID NO 22:
2
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 23 - Ceres seq_id 1009346
- Location of start within SEQ ID NO 22: at 50 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 23: at 22 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 15
- gi No. 3176705 - Description:
- % Identity: 53.3
- Alignment Length: 75
- Location of Alignment in SEQ ID NO 23: from 1 to 75
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 24
- Ceres seq_id 1009347
- Location of start within SEQ ID NO 22: at 62 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 24: at 18 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 16
- gi No. 3176705
- Description:
- % Identity: 53.3
- Alignment Length: 75 - Location of Alignment in SEQ ID NO 24: from 1 to
71
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 6349 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 25
- Ceres seq_id 1010140 - Alternative transcription start site(s) located in SEQ ID NO 25:
-31, -29, 4, 5, 6, 10, 17, 34, 41, 749
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 26
- Ceres seq_id 1010141
- Location of start within SEQ ID NO 25: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Bacterial regulatory proteins, deoR family
- Location within SEQ ID NO 26: from 57 to 95 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 17
- gi No. 3257798
- Description:
- % Identity: 40.6
- Alignment Length: 234 - Location of Alignment in SEQ ID NO 26: from 56 to
289 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 27
- Ceres seq_id 1010142 - Location of start within SEQ ID NO 25: at 42 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Bacterial regulatory proteins, deoR family - Location within SEQ ID NO 27: from 44 to 82 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 18
- gi No. 3257798 - Description:
- % Identity: 40.6
- Alignment Length: 234
- Location of Alignment in SEQ ID NO 27: from 43 to
276
|B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 28
- Ceres seq_id 1010143
- Location of start within SEQ ID NO 25: at 231 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 19 - gi No. 3257798
- Description:
- % Identity: 40.6
- Alignment Length: 234
- Location of Alignment in SEQ ID NO 28: from 1 to 213
Maximum Length Sequence: related to: Clone IDs: 6261
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 29
- Ceres seq_id 1010217
- Alternative transcription start site(s) located in SEQ ID NO 29:
2,5,15
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 30 - Ceres seq_id 1010218
- Location of start within SEQ ID NO 29: at 85 nt . - Location of Signal Peptide Cleavage Site within SEQ ID NO 30: at 22 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 20
- gi No. 3341723
- Description: - % Identity: 64.3
- Alignment Length: 131
- Location of Alignment in SEQ ID NO 30: from 1 to 118 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 31
- Ceres seq_id 1010219
- Location of start within SEQ ID NO 29: at 118 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 31: at 13 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 21
- gi No. 3341723
- Description:
- % Identity: 64.3
- Alignment Length: 131 - Location of Alignment in SEQ ID NO 31: from 1 to
107
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 32 - Ceres seq_id 1010220
- Location of start within SEQ ID NO 29: at 121 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 22
- gi No. 3341723
- Description:
- % Identity: 64.3 - Alignment Length: 131
- Location of Alignment in SEQ ID NO 32: from 1 to 106
(Ba) Polypeptide Activities: Similar to Constans like Protein activities and Zinc Finger Protein Activities. Maximum Length Sequence: related to: Clone IDs: 6145 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 33
- Ceres seq_id 1010302
- Alternative transcription start site(s) located in SEQ ID NO 33:
-5, -3, -2, -1,2, 3, 4, 5, 6, 7, 8, 10, 11, 12, 13, 15, 19, 23, 45, 349
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 34
- Ceres seq_id 1010303
- Location of start within SEQ ID NO 33: at 59 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Pathogenesis-related protein Bet v I family
- Location within SEQ ID NO 34: from 5 to 155 aa
Dp) Related Amino Acid Sequences
- Alignment No. 23
- gi No. 1321731
- Description:
- % Identity: 35.7
- Alignment Length: 159
- Location of Alignment in SEQ ID NO 34: from 5 to
155
Maximum Length Sequence related to: Clone IDs: 5180
Public Genomic DNA: gi No: 4757410 Predicted Exons: INTR 37202 . 37397 OCKHAMG-CDNA INTR 37493 . 37825 OCKHAMG-CDNA
INIT 37271 ... 37397 OCKHAMG-CDS TERM 37493 ... 37704 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 35
- Ceres seq_id 1010815
- Alternative transcription start site(s) located in SEQ ID NO 35:
15,16,17,18,19,29,31,34
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 36
- Ceres seq_id 1010816
- Location of start within SEQ ID NO 35: at 70 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 24
- gi No. 2879811 - Description:
- % Identity: 88.4
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 36: from 1 to 112
|B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 37
- Ceres seq_id 1010817
- Location of start within SEQ ID NO 35: at 133 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 25 - gi No. 2879811
- Description:
- % Identity: 88.4
- Alignment Leigth: 112
- Location of Alignment in SEQ ID NO 37: from 1 to 91
(B) Polypeptide Sequence
- Par. Appln. SEQ ID NO 38
- Ceres seq_id 1010818 - Location of start within SEQ ID NO 35: at 257 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 38 : at 26 aa .
(Ba) Polypeptide Activities: Similar to ribosomal protein actitivies.
Maximum Length Sequence: related to: Clone IDs: 42842
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 39
- Ceres seq_id 1011437
- Alternative transcription start site(s) located in SEQ ID NO 39:
-28 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 40
- Ceres seq_id 1011438 - Location of start within SEQ ID NO 39: at 2 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 41
- Ceres seq_id 1011439 - Location of start within SEQ ID NO 39: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 41: at 29 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 26
- gi No. 3334271
- Description: - % Identity: 29.6
- Alignment Length: 54
- Location of Alignment in SEQ ID NO 41: from 13 to 65 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 42
- Ceres seq_id 1011440
- Location of start within SEQ ID NO 39: at 28 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 42: at 20 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 27
- gi No. 3334271
- Description:
- % Identity: 29.6
- Alignment Length: 54 - Location of Alignment in SEQ ID NO 42: from 4 to
56
(Ba) Polypeptide Activities: Similar to NADH Oxidoxductase MWFE Subunit Protein Activities.
Maximum Length Sequence: related to: Clone IDs: 42475
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 43
- Ceres seq__id 1011616
- Alternative transcription start site(s) located in SEQ ID NO 43: 3,5,476
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 44
- Ceres seq_id 1011617 - Location of start within SEQ ID NO 43: at 115 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 28
- gi No. 3859560
- Description:
- % Identity: 36.2
- Alignment Length: 225 - Location of Alignment in SEQ ID NO 44: from 31 to
248
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 45 - Ceres seq_id 1011618
- Location of start within SEQ ID NO 43: at 406 nt .
(C) Nomination and Annotation of Doma__. ^s within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 29
- gi No. 3859560
- Description:
- % Identity: 36.2 - Alignment Length: 225
- Location of Alignment in SEQ ID NO 45: from 1 to 151
(Ba) Polypeptide Activities: Similar to acycl-protein thioosterases protein activities, calcium independent phospholipase A2 activities, and carboxylesterase activities.
Maximum Length Sequence: related to: Clone IDs:
42405 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 46 - Ceres seq id 1011631 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 47 - Ceres seq_id 1011632
- Location of start within SEQ ID NO 46: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 30
- gi No. 3618318
- Description:
- % Identity: 72.7 - Alignment Length: 44
- Location of Alignment in SEQ ID NO 47: from 91 to 134
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 48
- Ceres seq_id 1011633
- Location of start within SEQ ID NO 46: at 9 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 31
- gi No. 3618318
- Description: - % Identity: 72.7
- Alignment Length: 44
- Location of Alignment in SEQ ID NO 48: from 89 to 132 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 49
- Ceres seq_id 1011634
- Location of start within SEQ ID NO 46: at 15 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 32
- gi No. 3618318 - Description:
- % Identity: 72.7
- Alignment Length: 44
- Location of Alignment in SEQ ID NO 49: from 87 to 130 (Ba) Polypeptide Activities: Similar to Constans protein activities, and zinc finger protein activities.
Maximum Length Sequence: related to: Clone IDs:
42240 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 50 - Ceres seq_id 1011714
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 51 - Ceres seq_id 1011715
- Location of start within SEQ ID NO 50: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Bacterial mutT protein
- Location within SEQ ID NO 51: from 26 to 67 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 33 - gi No. 2129134
- Description:
- % Identity: 40.8
- Alignment Length: 121
- Location of Alignment in SEQ ID NO 51: from 12 to 131
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 52
- Ceres seq_id 1011716 - Location of start within SEQ ID NO 50: at 14 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Bacterial mutT protein - Location within SEQ ID NO 52: from 22 to 63 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 34
- gi No. 2129134 - Description:
- % Identity: 40.8
- Alignment Length: 121
- Location of Alignment in SEQ ID NO 52: from 8 to
127
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 53
- Ceres seq_id 1011717
- Location of start within SEQ ID NO 50: at 185 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 35
- gi No. 2129134 - Description:
- % Identity: 40.8
- Alignment Length: 121
- Location of Alignment in SEQ ID NO 53: from 1 to 70
Maximum Length Sequence: related to: Clone IDs: 42169 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 54
- Ceres seq_id 1011784
- Alternative transcription start site(s) located in SEQ ID NO 54: -15,-4,7,402
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 55
- Ceres seq_id 1011785 - Location of start within SEQ ID NO 54: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 55: at 42 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 55: from 45 to 108 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 36
- gi No. 543565
- Description:
- % Identity: 56.5
- Alignment Length: 85 - Location of Alignment in SEQ ID NO 55: from 29 to
110
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 56 - Ceres seq_id 1011786
- Location of start within SEQ ID NO 54: at 49 nt . - Location of Signal Peptide Cleavage Site within SEQ ID NO 56: at 26 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 56: from 29 to 92 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 37
- gi No. 543565
- Description:
- % Identity: 56.5
- Alignment Length: 85 - Location of Alignment in SEQ ID NO 56: from 13 to
94
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 57 - Ceres seq_id 1011787
- Location of start within SEQ ID NO 54: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to: Clone IDs: 41992
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 58
- Ceres seq_id 1011820
- Alternative transcription start site(s) located in SEQ ID NO 58:
-40,37
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 59 - Ceres seq_id 1011821
- Location of start within SEQ ID NO 58: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 38
- gi No. 3417418
- Description:
- % Identity: 23.6 - Alignment Length: 207 - Location of Alignment in SEQ ID NO 59: from 24 to
226
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 60
- Ceres seq_id 1011822
- Location of start within SEQ ID NO 58: at 13 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 39
- gi No. 3417418
- Description: - % Identity: 23.6
- Alignment Length: 207
- Location of Alignment in SEQ ID NO 60: from 20 to 222 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 61
- Ceres seq__id 1011823
- Location of start within SEQ ID NO 58: at 151 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 40
- gi No. 3417418 - Description:
- % Identity: 23.6
- Alignment Length: 207
- Location of Alignment in SEQ ID NO 61: from 1 to 176
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 41851 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 62
- Ceres seq id 1011874
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 63 - Ceres seq_id 1011875
- Location of start within SEQ ID NO 62: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 41
- gi No. 2911044
- Description: - % Identity: 78.7
- Alignment Length: 95
- Location of Alignment in SEQ ID NO 63: from 28 to 121
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 41682
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 64
- Ceres seq_id 1011981
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 65
- Ceres seq_id 1011982
- Location of start within SEQ ID NO 64: at 68 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 42 - gi No. 4115355
- Description:
- % Identity: 100
- Alignment Length: 52
- Location of Alignment in SEQ ID NO 65: from 1 to 52
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 66
- Ceres seq_id 1011983 - Location of start within SEQ ID NO 64: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
[B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 67
- Ceres seq_id 1011984
- Location of start within SEQ ID NO 64: at 483 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 67: at 19 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 38470
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 68
- Ceres seq_id 1014547
- Alternative transcription start site(s) located in SEQ ID NO 68:
-39,-2,-1,2, 3,7, 8, 9, 10
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 69 - Ceres seq_id 1014548
- Location of start within SEQ ID NO 68: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 69: at 32 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 69: from 44 to 110 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 43
- gi No. 3062791
- Description:
- % Identity: 72.2 - Alignment Length: 90
- Location of Alignment in SEQ ID NO 69: from 21 to 110
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 70
- Ceres seq_id 1014549
- Location of start within SEQ ID NO 68: at 25 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 70: at 24 aa. (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 70: from 36 to 102 aa ,
(Dp) Related Amino Acid Sequences
- Alignment No. 44
- gi No. 3062791
- Description: - % Identity: 72.2
- Alignment Length: 90
- Location of Alignment in SEQ ID NO 70: from 13 to 102 Maximum Length Sequence: related to: Clone IDs:
38004 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 71
- Ceres seq_id 1014995
- Alternative transcription start site(s) located in SEQ ID NO 71:
2,3,4
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 72
- Ceres seq_id 1014996
- Location of start within SEQ ID NO 71: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Aminotransferase class IV
- Location within SEQ ID NO 72: from 71 to 334 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 45
- gi No. 3540183
- Description: - % Identity: 54.7
- Alignment Length: 287
- Location of Alignment in SEQ ID NO 72: from 56 to 341 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 73
- Ceres seq_id 1014997
- Location of start within SEQ ID NO 71: at 65 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) - Aminotransferase class IV
- Location within SEQ ID NO 73: from 50 to 313 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 46
- gi No. 3540183
- Description:
- % Identity: 54.7
- Alignment Length: 287 - Location of Alignment in SEQ ID NO 73: from 35 to
320
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 74 - Ceres seq_id 1014998
- Location of start within SEQ ID NO 71: at 167 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Aminotransferase class IV
- Location within SEQ ID NO 74: from 16 to 279 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 47 - gi No. 3540183
- Description:
- % Identity: 54.7
- Alignment Length: 287
- Location of Alignment in SEQ ID NO 74: from 1 to 286
Maximum Length Sequence: related to: Clone IDs: 37701
Public Genomic DNA: gi No: 4699904 Predicted Exons:
SINGLE 38530 ... 37988 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 75
- Ceres seq_id 1015323
- Alternative transcription start site(s) located in SEQ ID NO 75: -1,5,6,12
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 76
- Ceres seq_id 1015324 - Location of start within SEQ ID NO 75: at 59 nt . - Location of Signal Peptide Cleavage Site within SEQ ID NO 76: at 25 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 48
- gi No. 3860308
- Description: - % Identity: 44.5
- Alignment Length: 140
- Location of Alignment in SEQ ID NO 76: from 56 to 175 (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs:
364 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 77
- Ceres seq_id 1016486
- Alternative transcription start site(s) located in SEQ ID NO 77:
17,19,20,21,22,23,29,35,38
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 78
- Ceres seq_id 1016487
- Location of start within SEQ ID NO 77: at 1 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 78: at 46 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Gamma-thionins family
- Location within SEQ ID NO 78: from 55 to 101 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 49 - gi No. 4038039
- Description:
- % Identity: 100
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 78: from 25 to 101 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 79
- Ceres seq_id 1016488
- Location of start within SEQ ID NO 77: at 73 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 79: at 22 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Gamma-thionins family
- Location within SEQ ID NO 79: from 31 to 77 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 50 - gi No. 4038039
- Description:
- % Identity: 100
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 79: from 1 to 77
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 80
- Ceres seq_id 1016489 - Location of start within SEQ ID NO 77: at 118 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Gamma-thionins family - Location within SEQ ID NO 80: from 16 to 62 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 51
- gi No. 4038039 - Description:
- % Identity: 100
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 80: from 1 to
62
Maximum Length Sequence: related to: Clone IDs: 33891 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 81
- Ceres seq_id 1018341
- Alternative transcription start site(s) located in SEQ ID NO 81: 4 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 82
- Ceres seq_id 1018342
- Location of start within SEQ ID NO 81: at 71 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 52 - gi No. 1064887
- Description:
- % Identity: 60
- Alignment Length: 65
- Location of Alignment in SEQ ID NO 82: from 2 to 66
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 83
- Ceres seq_id 1018343 - Location of start within SEQ ID NO 81: at 143 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 53
- gi No. 1064887
- Description:
- % Identity: 60
- Alignment Length: 65 - Location of Alignment in SEQ ID NO 83: from 1 to
42
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 84 - Ceres seq_id 1018344
- Location of start within SEQ ID NO 81: at 146 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 54
- gi No. 1064887
- Description:
- % Identity: 60 - Alignment Length: 65
- Location of Alignment in SEQ ID NO 84: from 1 to 41
(Ba) Polypeptide Activities: Similar to pollen coat protein activities and LEA protein activities. Maximum Length Sequence: related to: Clone IDs: 33828 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 85
- Ceres seq_id 1018382
- Alternative transcription start site(s) located in SEQ ID NO 85: 2,4,5,6,7,8,9,10,11,14
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 86
- Ceres seq_id 1018383 - Location of start within SEQ ID NO 85: at 22 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 86: at 24 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 86: from 28 to 115 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 55
- gi No. 899224
- Description:
- % Identity: 78.2
- Alignment Length: 119 - Location of Alignment in SEQ ID NO 86: from 1 to
119
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 87 - Ceres seq_id 1018384
- Location of start within SEQ ID NO 85: at 73 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Plant lipid transfer protein family
- Location within SEQ ID NO 87: from 11 to 98 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 56 - gi No. 899224
- Description:
- % Identity: 78.2
- Alignment Length: 119
- Location of Alignment in SEQ ID NO 87: from 1 to 102 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 88
- Ceres seq_id 1018385
- Location of start within SEQ ID NO 85: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences Maximum Length Sequence: related to: Clone IDs:
30349 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 89
- Ceres seq_id 1020666
- Alternative transcription start site(s) located in SEQ ID NO 89:
33, 35, 39, 40, 42, 43, 44, 45, 64, 173
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 90
- Ceres seq_id 1020667
- Location of start within SEQ ID NO 89: at 118 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S7e
- Location within SEQ ID NO 90: from 7 to 187 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 57
- gi No. 3851636
- Description: - % Identity: 77.4
- Alignment Length: 190
- Location of Alignment in SEQ ID NO 90: from 1 to 190 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 91
- Ceres seq_id 1020668
- Location of start within SEQ ID NO 89: at 271 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein S7e
- Location within SEQ ID NO 91: from 1 to 136 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 58 gi No. 3851636 Description : % Identity: 77.4 Alignment Length: 190 Location of Alignment in SEQ ID NO 91 from 1 to
139
Maximum Length Sequence: related to: Clone IDs:
30113 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 92
- Ceres seq id 1020784
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 93
- Ceres seq_id 1020785
- Location of start within SEQ ID NO 92: at 60 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 93: at 25 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 59
- gi No. 3860308
- Description:
- % Identity: 44.5
- Alignment Length: 140 - Location of Alignment in SEQ ID NO 93: from 56 to
175
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
29120 Public Genomic DNA: gi No: 5822667
Predicted Exons: INTR 68772 . 69532 OCKHAMG-CDNA
SINGLE 68846 69325 OCKHAMG-CDS gi No: 6041831 Predicted Exons: INTR 63702 64462 OCKHAMG-CDNA
SINGLE 63776 ... 64255 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 94
- Ceres seq_id 1021525
- Alternative transcription start site(s) located in SEQ ID NO 94:
25,26,27,28,29,35,36,39,51,53,54,68
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 95
- Ceres seq_id 1021526
- Location of start within SEQ ID NO 94: at 75 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 60
- gi No. 4388980
- Description:
- % Identity: 29.1
- Alignment Length: 110
- Location of Alignment in SEQ ID NO 95: from 47 to 156
(Ba) Polypeptide Activities: Similar to adrenodoxi precursor protein activities and adrenal ferredoxin activities.
Maximum Length Sequence: related to: Clone IDs: 2891
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 96
- Ceres seq_id 1021563
- Alternative transcription start site(s) located in SEQ ID NO 96:
16, 28, 29, 30, 31, 35, 36, 43, 74, 77, 80, 88, 89, 90, 95
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 97 - Ceres seq_id 1021564
- Location of start within SEQ ID NO 96: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 61 - gi No. 2493089
- Description:
- % Identity: 29.7
- Alignment Length: 77 - Location of Alignment in SEQ ID NO 97: from 52 to
125
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 98 - Ceres seq_id 1021565
- Location of start within SEQ ID NO 96: at 116 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 62
- gi No. 2493089
- Description:
- % Identity: 29.7 - Alignment Length: 77
- Location of Alignment in SEQ ID NO 98: from 14 to 87
(Ba) Polypeptide Activities: Similar to ATPK-mouse activities, ATP synthase activities, and mitochondrial F- Chain activities.
Maximum Length Sequence: related to: Clone IDs: 28979 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 99
- Ceres seq_id 1021576 - Alternative transcription start site(s) located in SEQ ID NO 99:
-13,- 11,3,5,7,11,12,13,15,24,26,28,29,31,34,35,36,37,38,39 43, 4, 45, 46, 47, 48, 50, 51, 52, 56, 58, 59, 61, 67, 68, 70, 75, 82, 83, 91,1 12
244,313,318
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 100
- Ceres seq_id 1021577
- Location of start within SEQ ID NO 99: at 109 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Photosystem I psaG / psaK - Location within SEQ ID NO 100: from 50 to 130 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 63
- gi No. 3885511
- Description:
- % Identity: 81.1
- Alignment Length: 128
- Location of Alignment in SEQ ID NO 100: from 1 to
127
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 101
- Ceres seq_id 1021578
- Location of start within SEQ ID NO 99: at 121 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Photosystem I psaG / psaK
- Location within SEQ ID NO 101: from 46 to 126 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 64
- gi No. 3885511
- Description:
- % Identity: 81.1
- Alignment Length: 128
- Location of Alignment in SEQ ID NO 101: from 1 to 123
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 102
- Ceres seq_id 1021579
- Location of start within SEQ ID NO 99: at 124 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Photosystem I psaG / psaK
- Location within SEQ ID NO 102: from 45 to 125 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 65
- gi No. 3885511
- Description: - % Identity: 81.1
- Alignment Length: 128
- Location of Alignment in SEQ ID NO 102: from 1 to 122 Maximum Length Sequence: related to: Clone I Ds :
28177 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 103
- Ceres seq_id 1021927
- Alternative transcription start sire(s) located in SEQ ID NO 103:
2,12,20,23,29,36,46,47,53
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 104
- Ceres seq_id 1021928
- Location of start within SEQ ID NO 103: at 67 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 66
- gi No. 4263779
- Description:
- % Identity: 28.2
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 104: from 14 to 182
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 105
- Ceres seq_id 1021929
- Location of start within SEQ ID NO 103: at 172 nt .
- Location of Signal Peptide Cleavage Sire within SEQ ID NO 105: at 23 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 67
- gi No. 4263779
- Description:
- % Identity: 28.2
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 105: from 1 to 147
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 106
- Ceres seq_id 1021930
- Location of start within SEQ ID NO 103: at 220 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 68
- gi No. 4263779
- Description:
- % Identity: 28.2 - Alignment Length: 177
- Location of Alignment in SEQ ID NO 106: from 1 to 131
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 2807
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 107
- Ceres seq_id 1021945
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 108
- Ceres seq_id 1021946
- Location of start within SEQ ID NO 107: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 69 - gi No. 3334132
- Description:
- % Identity: 27.4
- Alignment Length: 114
- Location of Alignment in SEQ ID NO 108: from 28 to 136
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 109
- Ceres seq_id 1021947 - Location of start within SEQ ID NO 107: at 163 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 70
- gi No. 3334132
- Description:
- % Identity: 27.4
- Alignment Length: 114 - Location of Alignment in SEQ ID NO 109: from 1 to
82 (Ba) Polypeptide Activities: Similar to C21 0RF4 - membrane protein activities Maximum Length Sequence: related to: Clone IDs:
27792 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 110
- Ceres seq_id 1022170
- Alternative transcription start site(s) located in SEQ ID NO 110:
-4,-1,32,68
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 111
- Ceres seq_id 1022171
- Location of start within SEQ ID NO 110: at 92 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 71 - gi No. 1173456
- Description:
- % Identity: 54.7
- Alignment Length: 129
- Location of Alignment in SEQ ID NO 111: from 4 to 131
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 112
- Ceres seq__id 1022172 - Location of start within SEQ ID NO 110: at 191 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 72
- gi No. 1173456
- Description:
- % Identity: 54.7
- Alignment Length: 129 - Location of Alignment in SEQ ID NO 112: from 1 to
98
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 113 - Ceres seq_id 1022173
- Location of start within SEQ ID NO 110: at 1 nt . - Location of Signal Peptide Cleavage Site within SEQ ID NO 113: at 19 aa.
(Ba) Polypeptide Activities: Similar to small nuclear ribonucleoprotein activities.
Maximum Length Sequence: related to: Clone IDs: 27167
Public Genomic DNA: gi No: 3046850 Predicted Exons:
INIT 45217 ... 45131 OCKHAMG-CDS INTR 44695 ... 44629 OCKHAMG-CDS
TERM 44554 ... 44286 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 114
- Ceres seq_id 1022554 - Alternative transcription start site(s) located in SEQ ID NO 114:
-49,- 19, 7, 22, 23, 28, 29, 30, 31, 32, 33, 35, 36, 37, 51, 57, 67, 75, 81, 82
85
>) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 115
- Ceres seq_id 1022555
- Location of start within SEQ ID NO 114: at 107 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Heme-binding domain in cytochrome b5 and oxidoreductases - Location within SEQ ID NO 115: from 7 to 84 aa .
Dp) Related Amino Acid Sequences
- Alignment No. 73
- gi No. 4240122
- Description:
- % Identity: 100
- Alignment Length: 140
- Location of Alignment in SEQ ID NO 115: from 1 to
140
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 116
- Ceres seq_id 1022556
- Location of start within SEQ ID NO 114: at 317 nt (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 74
- gi No. 4240122
- Description:
- % Identity: 100
- Alignment Length: 140 Location of Alignment in SEQ ID NO 116: from 1 to
70
Maximum Length Sequence: related to: Clone IDs: 27109
Public Genomic DNA: gi No: 6449507 Predicted Exons:
INIT 94711 ... 94519 OCKHAMG-CDS INTR 94417 ... 94326 OCKHAMG-CDS
INTR 94249 ... 94131 OCKHAMG-CDS
TERM 94046 ... 93968 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 117 - Ceres seq_id 1022594
- Alternative transcription start site(s located in SEQ ID NO 117:
2, 15,24,25, 66,69,72,74
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 118
- Ceres seq_id 1022595
- Location of start within SEQ ID NO 117 at 1 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Universal stress protein family
- Location within SEQ ID NO 118: from 98 to 183 aa
'Dp) Related Amino Acid Sequences
- Alignment No. 75
- gi No. 2160182
- Description:
- % Identity: 37.5
- Alignment Length: 160
- Location of Alignment in SEQ ID NO 118: from 39 to 186
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 119
- Ceres seq_id 1022596 - Location of start within SEQ ID NO 117: at 82 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Universal stress protein family
- Location within SEQ ID NO 119: from 71 to 156 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 76 - gi No. 2160182
- Description:
- % Identity: 37.5
- Alignment Length: 160
- Location of Alignment in SEQ ID NO 119: from 12 to 159
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 120
- Ceres seq_id 1022597 - Location of start within SEQ ID NO 117: at 106 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Universal stress protein family - Location within SEQ ID NO 120: from 63 to 148 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 77
- gi No. 2160182 - Description:
- % Identity: 37.5
- Alignment Length: 160
- Location of Alignment in SEQ ID NO 120: from 4 to
151
(Ba) Polypeptide Activities: Similar to protein in methanobacterium thermoautotrophicum activities.
Maximum Length Sequence: related to: Clone IDs:
26994 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 121 - Ceres seq_id 1022621
- Alternative transcription start site(s) located in SEQ ID NO 121:
2,7, 9,13,35,38,45,57 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 122 - Ceres seq_id 1022622
- Location of start within SEQ ID NO 121: at 86 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 78
- gi No. 3256599
- Description: - % Identity: 32
- Alignment Length: 128
- Location of Alignment in SEQ ID NO 122: from 7 to 128 (Ba) Polypeptide Activities: Similar to structural cell wall protein activities, and larval gene protein in the Fruit fly activities .
Maximum Length Sequence: related to: Clone IDs:
23518 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 123
- Ceres seq_id 1024375
- Alternative transcription start site(s) located in SEQ ID NO 123:
7, 8, 10, 17, 18, 24, 35, 41, 2, 43, 44, 46, 48, 52, 54, 59
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 124
- Ceres seq_id 1024376
- Location of start within SEQ ID NO 123: at 130 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S7e
- Location within SEQ ID NO 124: from 7 to 187 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 79
- gi No. 3851636
- Description: - % Identity: 76.6
- Alignment Length: 188
- Location of Alignment in SEQ ID NO 124: from 1 to
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 125 - Ceres seq_id 1024377
- Location of start within SEQ ID NO 123: at 283 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S7e
- Location within SEQ ID NO 125: from 1 to 136 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 80
- gi No. 3851636
- Description:
- % Identity: 76.6
- Alignment Length: 188 - Location of Alignment in SEQ ID NO 125: from 1 to
137
Maximum Length Sequence: related to: Clone IDs: 23170 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 126
- Ceres seq_id 1024535 - Alternative transcription start site(s) located in SEQ ID NO 126:
2,8,11,31,46,47,48
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 127
- Ceres seq_id 1024536
- Location of start within SEQ ID NO 126: at 115 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 81
- gi No. 2621731
- Description: - % Identity: 35.2
- Alignment Length: 88
- Location of Alignment in SEQ ID NO 127: from 5 to 92 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 128
- Ceres seq_id 1024537
- Location of start within SEQ ID NO 126: at 3 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 129 - Ceres seq_id 1024538
- Location of start within SEQ ID NO 126: at 253 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 82
- gi No. 2621731
- Description:
- % Identity: 35.2 - Alignment Length: 88
- Location of Alignment in SEQ ID NO 129: from 1 to 46
(Ba) Polypeptide Activities: Similar to small nuclear ribonucleoprotein activities.
Maximum Length Sequence: related to: Clone IDs:
21228 Public Genomic DNA: gi No: 4539402 Predicted Exons: INIT 36726 36352 GENBANK INTR 36257 36135 GENBANK TERM 35555 35469 GENBANK
INTR 36791 36352 OCKHAMG-CDNA INTR 36257 36135 OCKHAMG-CDNA INTR 35555 35325 OCKHAMG-CDNA
INIT 36726 ... 36352 OCKHAMG-CDS INTR 36257 ... 36135 OCKHAMG-CDS TERM 35555 ... 35469 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 130
- Ceres seq_id 1025683
- Alternative transcription start site(s) located in SEQ ID NO 130:
2,8,22
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 131
- Ceres seq_id 1025684
- Location of start within SEQ ID NO 130: at 3 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L6 - Location within SEQ ID NO 131: from 34 to 216 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 83
- gi No. 266945 - Description:
- % Identity: 84
- Alignment Length: 194
- Location of Alignment in SEQ ID NO 131: from 23 to 216
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 132
- Ceres seq_id 1025685
- Location of start within SEQ ID NO 130: at 69 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L6
- Location within SEQ ID NO 132: from 12 to 194 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 84
- gi No. 266945
- Description: - % Identity: 84
- Alignment Length: 194
- Location of Alignment in SEQ ID NO 132: from 1 to 194 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 133
- Ceres seq_id 1025686
- Location of start within SEQ ID NO 130: at 96 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein L6
- Location within SEQ ID NO 133: from 3 to 185 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 85
- gi No. 266945
- Description:
- % Identity: 84 - Alignment Length: 194 - Location of Alignment in SEQ ID NO 133: from 1 to 185
Maximum Length Sequence: related to: Clone IDs:
19274 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 134 - Ceres seq_id 1027152
- Alternative transcription start site(s) located in SEQ ID NO 134:
-350,3,4,10,11,13,222 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 135
- Ceres seq_id 1027153
- Location of start within SEQ ID NO 134: at 3 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 86
- gi No. 2879811 - Description:
- % Identity: 86.6
- Alignment Length: 112
- Location of Alignment in S ^ ID NO 135: from 26 to 137
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 136
- Ceres seq_id 1027154
- Location of start within SEQ ID NO 134 at 7S nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 87 - gi No. 2879811
- Description:
- % Identity: 86.6
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 136: from 1 to 112
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 137
- Ceres seq_id 1027155 - Location of start within SEQ ID NO 134: at 141 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 88 - gi No. 2879811
- Description:
- % Identity: 86.6
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 137: from 1 to 91
(Ba) Polypeptide Activities: Similar to ribosomal L30 protein activities.
Maximum Length Sequence: related to: Clone IDs: 17835 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 138
- Ceres seq__id 1028095
- Alternative transcription start site(s) located in SEQ ID NO 138: -2, 2, 3, , 5, 6, 12, 14, 18, 22, 26, 40, 42, 4, 45, 46, 47
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 139
- Ceres seq_id 1028096 - Location of start within SEQ ID NO 138: at 55 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 139: at 29 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 89
- gi No. 4336325
- Description: - % Identity: 31.7
- Alignment Length: 126
- Location of Alignment in SEQ ID NO 139: from 15 to 135 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 140
- Ceres seq_id 1028097
- Location of start within SEQ ID NO 138: at 214 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 90
- gi No. 4336325
- Description:
- % Identity: 31.7
- Alignment Length: 126
- Location of Alignment in SEQ ID NO 140: from 1 to
(B) Polypeptide Se^ence
- Pat. Appln. SEQ ID NO 141
- Ceres seq_id 1028098
- Location of start within SEQ ID NO 138: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 141: at 16 aa .
(Ba) Polypeptide Activities: Similar to human C214 membrane protein activities.
Maximum Length Sequence: related to: Clone IDs: 17075 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 142
- Ceres seq_id 1028608
- Alternative transcription start site(s) located in SEQ ID NO 142: -4,2,28,31,36,49,59
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 143
- Ceres seq_id 1028609 - Location of start within SEQ ID NO 142: at 95 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 91
- gi No. 2735528
- Description:
- % Identity: 33.9
- Alignment Length: 118 - Location of Alignment in SEQ ID NO 143: from 64 to 178
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 144 - Ceres seq_id 1028610
- Location of start within SEQ ID NO 142: at 176 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 92
- gi No. 2735528
- Description:
- % Identity: 33.9
- Aliynment Length: 118 - Location of Alignment in SEQ ID NO 144: from 37 to 151
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 145 - Ceres seq_id 1028611
- Location of start within SEQ ID NO 142: at 381 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 145: at 41 aa . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to: Clone IDs: 1505 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 146 - Ceres seq_id 1030069
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 147 - Ceres seq_id 1030070
- Location of start within SEQ ID NO 146: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 93
- gi No. 4335755
- Description:
- % Identity: 63.6 - Alignment Length: 143
- Location of Alignment in SEQ ID NO 147: from 34 to 171
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 148
- Ceres seq id 1030071 - Location of start within SEQ ID NO 146: at 50 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 94
- gi No. 4335755
- Description:
- % Identity: 63.6 - Alignment Length: 143
- Location of Alignment in SEQ ID NO 148: from 18 to 155
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 149
- Ceres seq_id 1030072
- Location of start within SEQ ID NO 146: at 170 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 95
- gi No. 4335755
- Description: - % Identity: 63.6
- Alignment Length: 143
- Location of Alignment in SEQ ID NO 149: from 1 to 115 (Ba) Polypeptide Activities: Similar to hydroxyproline-rich protein activities.
Maximum Length Sequence: related to: Clone IDs:
12487 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 150 - Ceres seq_id 1032069
- Alternative transcription start site(s) located in SEQ ID NO 150:
4, 17 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 151
- Ceres seq_id 1032070
- Location of start within SEQ ID NO 150: at 74 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 96
- gi No. 3386621
- Description: - % Identity: 97.4
- Alignment Length: 234
- Location of Alignment in SEQ ID NO 151: from 1 to 231 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 152
- Ceres seq_id 1032071
- Location of start within SEQ ID NO 150: at 122 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 97
- gi No. 3386621 - Description:
- % Identity: 97.4
- Alignment Length: 234
- Location of Alignment in SEQ ID NO 152: from 1 to 215
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
11466 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 153 - Ceres seq_id 1033557
- Alternative transcription start site(s) located in SEQ ID NO 153:
62, 64, 65, 67, 72, 73, 74, 75, 166 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 154
- Ceres seq_id 1033558
- Location of start within SEQ ID NO 153: at 94 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein L34
- Location within SEQ ID NO 154: from 105 to 145 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 98
- gi No. 132909
- Description:
- % Identity: 70 - Alignment Length: 30
- Location of Alignment in SEQ ID NO 154: from 116 to 145
(Ba) Polypeptide Activities: Similar to 50S ribosomal protein L34 activities.
Maximum Length Sequence: related to: Clone IDs: 21589
106951 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 155
- Ceres seq_id 1034688 - Alternative transcription start site(s) located in SEQ ID NO 155: 2
- Clone 21589 starts at 2 and ends at in cDNA. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 156
- Ceres seq_id 1034689
- Location of start within SEQ ID NO 155: at 2 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 99
- gi No. 4335755 - Description:
- % Identity: 65
- Alignment Length: 143
- Location of Alignment in SEQ ID NO 156: from 33 to 170
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 157
- Ceres seq_id 1034690
- Location of start within SEQ ID NO 155: at 47 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 100 - gi No. 4335755
- Description: - % Identity: 65
- Alignment Length: 143
- Location of Alignment in SEQ ID NO 157: from li to 155
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 158
- Ceres seq_id 1034691
- Location of start within SEQ ID NO 155: at 167 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 101 - gi No. 4335755
- Description:
- % Identity: 65
- Alignment Length: 143
- Location of Alignment in SEQ ID NO 158: from 1 to 115
(Ba) Polypeptide Activities: Similar to hydroxy proline rich glycoprotein activities.
Maximum Length Sequence: related to: Clone IDs: 10433 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 159
- Ceres seq_id 1035033
- Alternative transcription start site(s) located in SEQ ID NO 159: 32
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 160
- Ceres seq_id 1035034 - Location of start within SEQ ID NO 159: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 160: at 47 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 102
- gi No. 3062795
- Description: - % Identity: 39.8
- Alignment Length: 83 - Location of Alignment in SEQ ID NO 160: from 24 to 99
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 161
- Ceres seq_id 1035035
- Location of start within SEQ ID NO 159: at 69 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 161: at 25 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 103 - gi No. 3062795
- Description:
- % Identity: 39.8
- Alignment Length: 83
- Location of Alignment in SEQ ID NO 161: from 2 to 77
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 162
- Ceres seq_id 1035036 - Location of start within SEQ ID NO 159: at 72 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 162: at 24 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 104
- gi No. 3062795
- Description: - % Identity: 39.8
- Alignment Length: 83
- Location of Alignment in SEQ ID NO 162: from 1 to 76 (Ba) Polypeptide Activities: Similar to Pollen coat protein activities .
Maximum Length Sequence: related to: Clone IDs:
10394 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 163 - Ceres seq_id 1035071 - Alternative transcription start site(s) located in SEQ ID NO 163:
-2, -1,2, 3, 18, 19, 21, 24, 25, 56, 66 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 164
- Ceres seq_id 1035072
- Location of start within SEQ ID NO 163: at 66 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- KH domain
- Location within SEQ ID NO 164: from 47 to 95 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 105
- gi No. 133940
- Description:
- % Identity: 76 - Alignment Length: 246
- Location of Alignment in SEQ ID NO 164: from 1 to 148
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 165
- Ceres seq_id 1035073
- Location of start within SEQ ID NO 163: at 195 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- KH domain
- Location within SEQ ID NO 165: from 4 to 52 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 106
- gi No. 133940
- Description:
- % Identity: 76
- Alignment Length: 246 - Location of Alignment in SEQ ID NO 165: from 1 to
105
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 166 - Ceres seq_id 1035074
- Location of start within SEQ ID NO 163: at 513 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 107 gi No. 133940 Description: % Identity: 76 Alignment Length: 246 Location of Alignment in SEQ ID NO 166: from 1 to
97
Maximum Length Sequence: related to: Clone IDs: 10511 Public Genomic DNA: gi No: 4539290 Predicted Exons: INTR 5588 5314 OCKHAMG-CDNA
INTR 5517 ... 5314 OCKHAMG-CDNA gi No: 4914454 Predicted Exons:
INTR 38937 ... 38663 OCKHAMG-CDNA
INTR 38866 ... 38663 OCKHAMG-CDNA (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 167 - Ceres seq_id 1376587
- Alternative transcription start site(s) located in SEQ ID NO 167:
8, 9, 10, 12, 13, 14, 15, 16, 17, 30, 34, 39, 41
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 168
- Ceres seq_id 1376588
- Location of start within SEQ ID NO 167: at 2 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 108
- gi No. 4539292
- Description:
- % Identity: 99.4
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 168: from 26 to 202
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 169
- Ceres seq_id 1376589
- Location of start within SEQ ID NO 167: at 77 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide ( s )
(Dp) Related Amino Acid Sequences
- Alignment No. 109
- gi No. 4539292
- Description:
- % Identity: 99.4
- Alignment Length: 177 - Location of Alignment in SEQ ID NO 169: from 1 to
177
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 170
- Ceres seq_id 1376590
- Location of start within SEQ ID NO 167 at 212 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 110
- gi No. 4539292
- Description:
- % Identity: 99.4
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 170: from 1 to
132
(Ba) Polypeptide Activities: Similar 40S ribosomal protein activities .
Maximum Length Sequence: related to: Clone IDs:
112110 Public Genomic DNA: gi No: 4263774 Predicted Exons:
INIT 1816 ... 1814 OCKHAMG- -CDS INTR 1290 1112 OCKHAMG- -CDS TERM 959 803 OCKHAMG- -CDS gi No: 4510360 Predicted Exons:
INIT 114707... 114705 OCKHAMG- -CDS
INTR 114181... 114003 OCKHAMG- -CDS
TERM 113850... 113694 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 171
- Ceres seq_id 1378581
- Alternative transcription start site(s) located in SEQ ID NO 171:
-35,-4,-3,18,20 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 172
- Ceres seq_id 1378582 - Location of start within SEQ ID NO 171: at 112 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 172: at 17 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- DnaJ domain
- Location within SEQ ID NO 172: from 57 to 101 aa.
(Dp) Related Amino Acid Sequences - Alignment No. Ill
- gi No. 4263775
- Description:
- % Identity: 100
- Alignment Length: 112 - Location of Alignment in SEQ ID NO 172: from 1 to
112
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 173 - Ceres seq_id 1378583
- Location of start within SEQ ID NO 171: at 256 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - DnaJ domain
- Location within SEQ ID NO 173: from 9 to 53 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 112 - gi No. 4263775
- Description:
- % Identity: 100
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 173: from 1 to 64
Maximum Length Sequence: related to: Clone IDs: 13599
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 174
- Ceres seq_id 1383462
- Alternative transcription start site(s) located in SEQ ID NO 174:
-2,2,3,4,5, 6,8,14,18,24 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 175
- Ceres seq_id 1383463 - Location of start within SEQ ID NO 174: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family - Location within SEQ ID NO 175: from 46 to 119 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 113
- gi No. 3128176 - Description:
- % Identity: 37
- Alignment Length: 194
- Location of Alignment in SEQ ID NO 175: from 23 to 197
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 176
- Ceres seq_id 1383464
- Location of start within SEQ ID NO 174: at 42 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 176: at 24 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Plant lipid transfer protein family
- Location within SEQ ID NO 176: from 33 to 106 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 114 - gi No. 3128176
- Description:
- % Identity: 37
- Alignment Length: 194
- Location of Alignment in SEQ ID NO 176: from 10 to 184
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 177
- Ceres seq_id 1383465 - Location of start within SEQ ID NO 174: at 90 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family - Location within SEQ ID NO 177: from 17 to 90 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 115
- gi No. 3128176
- Description: - % Identity: 37
- Alignment Length: 194
- Location of Alignment in SEQ ID NO 177: from 1 to 168 Maximum Length Sequence: related to: Clone IDs:
156375 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 178
- Ceres seq_id 1386215
- Alternative transcription start site(s) located in SEQ ID NO 178:
-38,12,17,18,19,20,26
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 179
- Ceres seq_id 1386216
- Location of start within SEQ ID NO 178: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Photosystem I psaG / psaK
- Location within SEQ ID NO 179: from 77 to 138 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 116
- gi No. 3885511
- Description: - % Identity: 79.3
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 179: from 28 to 138 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 180
- Ceres seq_id 1386217
- Location of start within SEQ ID NO 178: at 83 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Photosystem I psaG / psaK
- Location within SEQ ID NO 180: from 50 to 111 aa , (Dp) Related Amino Acid Sequences
- Alignment No. 117 - gi No. 3885511
- Description:
- % Identity: 79.3
- Alignment Length: 112 - Location of Alignment in SEQ ID NO 180: from 1 to
111
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 181 - Ceres seq_id 1386218
- Location of start within SEQ ID NO 178: at 95 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Photosystem I psaG / psaK
- Location within SEQ ID NO 181: from 46 to 107 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 118 - gi No. 3885511
- Description:
- % Identity: 79.3
- Alignment Length: 112
- Location of Alignment in SEQ ID NO 181: from 1 to 107
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 182
- Ceres seq_id 2025156 - Location of start within SEQ ID NO 178: at 502 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to: Clone IDs: 21233 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 183
- Ceres seq_id 1388499
- Alternative transcription start site(s) located in SEQ ID NO 183: 2,5,6,10,16,30,89,346,349
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 184
- Ceres seq_id 1388500 - Location of start within SEQ ID NO 183: at 62 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 119 - gi No. 2829899
- Description:
- % Identity: 49.3
- Alignment Length: 150
- Location of Alignment in SEQ ID NO 184: from 2 to 150
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 185
- Ceres seq_id 1388501 - Location of start within SEQ ID NO 183: at 122 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 120
- gi No. 2829899
- Description:
- % Identity: 49.3
- Alignment Length: 150 - Location of Alignment in SEQ ID NO 185: from 1 to
130
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 186 - Ceres seq_id 1388502
- Location of start within SEQ ID NO 183: at 266 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 121
- gi No. 2829899
- Description:
- % Identity: 49.3 - Alignment Length: 150
- Location of Alignment in SEQ ID NO 186: from 1 to 82
(Ba) Polypeptide Activities: Similar to major latex protein activities.
Maximum Length Sequence: related to: Clone IDs: 21304 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 187
- Ceres seq id 1388519
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 188
- Ceres seq_id 1388520 - Location of start within SEQ ID NO 187: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 188: at 38 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 122
- gi No. 4584110
- Description: - % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 188: from 20 to 182 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 189
- Ceres seq_id 1388521
- Location of start within SEQ ID NO 187: at 58 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 189: at 19 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 123
- gi No. 4584110
- Description:
- % Identity: 48.5
- Alignment Length: 163 - Location of Alignment in SEQ ID NO 189: from 1 to
163
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 190 - Ceres seq_id 1388522
- Location of start within SEQ ID NO 187: at 73 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 190: at 14 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 124
- gi No. 4584110
- Description: - % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 190: from 1 to 158 (Ba) Polypeptide Activities: Similar to pollen specific protein activities.
Maximum Length Sequence: related to: Clone IDs: 2153 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 191
- Ceres seq_id 1388563 - Alternative transcription start site(s) located in SEQ ID NO 191:
-3,-2,-1,13, 15, 146
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 192
- Ceres seq_id 1388564
- Location of start within SEQ ID NO 191: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 193 - Ceres seq_id 1388565
- Location of start within SEQ ID NO 191: at 306 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 125
- gi No. 3927834
- Description:
- % Identity: 31.5 - Alignment Length: 108
- Location of Alignment in SEQ ID NO 193: from 1 to 43
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 194
- Ceres seq id 1388566 - Location of start within SEQ ID NO 191: at 455 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 194: at 36 aa .
(Ba) Polypeptide Activities: Similar to hydroxproline-rich glycoprotein activities.
Maximum Length Sequence: related to: Clone IDs:
22488 Public Genomic DNA: gi No: 5708384 Predicted Exons:
INIT 82228 ... 82063 OCKHAMG- -CDS TERM 81730 ... 81381 OCKHAMG- -CDS gi No: 5732090 Predicted Exons : INIT 21301 ... 21136 OCKHAMG- -CDS
TERM 20803 ... 20454 OCKHAMG- -CDS gi No: 5870169 Predicted Exons:
INIT 89258 ... 89423 OCKHAMG- -CDS TERM 89756 ... 90105 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 195
- Ceres seq_id 1388793
- Alternative transcription start site(s) located in SEQ ID NO 195:
7, 14, 15, 20, 24, 30, 33, 42, 4, 58, 63, 64, 66, 76, 94, 97, 98, 99, 101, 102 103, 104, 105, 106, 108, 109, 110, 115, 116, 117 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 196
- Ceres seq_id 1388794
- Location of start within SEQ ID NO 195: at 154 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 196: at 19 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 126
- gi No. 4584110
- Description:
- % Identity: 48.5
- Alignment Length: 163 Location of Alignment in SEQ ID NO 196: from 1 to
163 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 197
- Ceres seq_id 1388795 - Location of start within SEQ ID NO 195: at 169 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 197: at 14 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 127
- gi No. 4584110
- Description: - % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 197: from 1 to 158
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 198
- Ceres seq_id 1388796
- Location of start within SEQ ID NO 195: at 205 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 128
- gi No. 4584110
- Description:
- % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 198: from 1 to 146
(Ba) Polypeptide Activities: Similar to pollen specific protein activities.
Maximum Length Sequence : related to:
Clone IDs:
26569
Public Genomic DNA: gi No: 6143856
Predicted Exons :
INTR 78628 ... 78255 OCKHAMG-CDNA
INTR 78160 ... 78004 OCKHAMG-CDNA
INTR 78624 ... 78255 OCKHAMG-CDNA
INTR 78160 ... 78004 OCKHAMG-CDNA INTR 78624 78255 OCKHAMG-CDNA INTR 78160 78006 OCKHAMG-CDNA
INTR 78624 78283 OCKHAMG-CDNA gi No: 6223633 Predicted Exons: INTR 78629 78256 OCKHAMG- -CDNA INTR 78161 78005 OCKHAMG--CDNA
INTR 78625 78256 OCKHAMG- -CDNA INTR 78161 78005 OCKHAMG--CDNA
INTR 78625 78256 OCKHAMG- -CDNA INTR 78161 78007 OCKHAMG--CDNA
INTR 78625 78284 OCKHAMG-CDNA
INIT 78587 ... 78256 OCKHAMG-CDS TERM 78161 ... 78152 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 199
- Ceres seq_id 1392041
- Alternative transcription start site(s located in SEQ ID NO 199:
3,4,5, 6,7,12
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 200
- Ceres seq_id 1392042
- Location of start within SEQ ID NO 199: at 45 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 200: at 19 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 200: from 23 to 112 aa.
' Op) Related Amino Acid Sequences
- Alignment No. 129
- gi No. 2497753
- Description:
- % Identity: 47
- Alignment Length: 117
- Location of Alignment in SEQ ID NO 200: from 4 to
113
Maximum Length Sequence: related to: Clone IDs: 28475 Public Genomic DNA: gi No: 5731404 Predicted Exons
INTR 70440 .. . 70346 OCKHAMG- -CDNA
INTR 70076 .. . 69865 OCKHAMG- -CDNA
INTR 69508 .. . 69434 OCKHAMG- -CDNA
INTR 69358 .. . 69284 OCKHAMG- -CDNA
INTR 69195 .. . 69115 OCKHAMG- -CDNA
INTR 69033 .. . 68959 OCKHAMG- -CDNA
INTR 68868 .. . 68695 OCKHAMG- -CDNA
INTR 68581 .. . 68344 OCKHAMG- -CDNA
INIT 70056 .. . 69865 OCKHAMG- -CDS
INTR 69508 .. . 69434 OCKHAMG- -CDS
INTR 69358 .. . 69284 OCKHAMG- -CDS
INTR 69195 .. . 69115 OCKHAMG- -CDS
INTR 69033 .. . 68959 OCKHAMG- -CDS
INTR 68868 .. 68695 OCKHAMG- -CDS
TERM 68581 .. . 68546 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 201
- Ceres seq_id 1393342
- Alternative transcription start site(s) located in SEQ ID NO 201:
16,48
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 202
- Ceres seq_id 1393343
- Location of start within SEQ ID NO 201: at 118 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
(Dp) Related Amino Acid Sequences
- Alignment No. 130
- gi No. 3386621
- Description:
- % Identity: 83
- Alignment Length: 224 Location of Alignment in SEQ ID NO 202: from 2 to
225
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
29453 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 203 - Ceres seq_id 1393556
- Alternative transcription start site(s) located in SEQ ID NO 203:
7,11,14,23,37,41,42,57, 61
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 204
- Ceres seq_id 1393557
- Location of start within SEQ ID NO 203: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 131 - gi No. 1082054
- Description:
- % Identity: 36.1
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 204: from 23 to 82
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 205
- Ceres seq_id 1393558 - Location of start within SEQ ID NO 203: at 69 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 205: at 41 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 132
- gi No. 1082054
- Description: - % Identity: 36.1
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 205: from 1 to 60 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 206
- Ceres seq_id 1393559
- Location of start within SEQ ID NO 203: at 72 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 206: at 40 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 133
- gi No. 1082054 - Description:
- % Identity: 36.1
- Alignment Length: 61
- Location of Alignment in SEQ ID NO 206: from 1 to 59
(Ba) Polypeptide Activities: Similar to transmembrane copper transporter protein activities.
Maximum Length Sequence: related to: Clone IDs: 42384 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 207
- Ceres seq_id 1396782
- Alternative transcription start site(s) located in SEQ ID NO 207: -1,29
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 208
- Ceres seq_id 1396783 - Location of start within SEQ ID NO 207: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 134
- gi No. 4512613
- Description:
- % Identity: 99.2
- Alignment Length: 122 - Location of Alignment in SEQ ID NO 208: from 11 to 132
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 209 - Ceres seq_id 1396784
- Location of start within SEQ ID NO 207: at 33 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 209: at 19 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 135
- gi No. 4512613 - Description:
- % Identity: 99.2 - Alignment Length: 122
- Location of Alignment in SEQ ID NO 209: from 1 to 122 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 210
- Ceres seq_id 1396785
- Location of start within SEQ ID NO 207: at 45 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 136
- gi No. 4512613 - Description:
- % Identity: 99.2
- Alignment Length: 122
- Location of Alignment in SEQ ID NO 210: from 1 to 118
(Ba) Polypeptide Activities: Similar to intergenic region of cyt2-MDHl of yeast activities.
Maximum Length Sequence: related to: Clone IDs:
42402 (Ac) cDNA Polynucleotide. Sequence
- Pat. Appln. SEQ ID NO 211 - Ceres seq_id 1396802
- Alternative transcription start site(s) located in SEQ ID NO 211:
-145,-56 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 212
- Ceres seq_id 1396803
- Location of start within SEQ ID NO 211: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 212: at 19 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 137
- gi No. 2463339
- Description:
- % Identity: 38.6
- Alignment Length: 70 - Location of Alignment in SEQ ID NO 212: from 136 to 205 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 213
- Ceres seq_id 1396804 - Location of start within SEQ ID NO 211: at 136 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 138
- gi No. 2463339
- Description:
- % Identity: 38.6
- Alignment Length: 70 - Location of Alignment in SEQ ID NO 213: from 91 to 160
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 214 - Ceres seq_id 1396805
- Location of start within SEQ ID NO 211: at 172 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 139
- gi No. 2463339
- Description:
- % Identity: 38.6 - Alignment Length: 70
- Location of Alignment in SEQ ID NO 214: from 79 to 148
(Ba) Polypeptide Activities: Similar to rbcX protein activities.
Maximum Length Sequence: related to: Clone IDs: 5105
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 215
- Ceres seq_id 1397130
- Alternative transcription start site(s) located in SEQ ID NO 215:
-1
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 216 - Ceres seq_id 1397131
- Location of start within SEQ ID NO 215: at 1 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 140
- gi No. 2827551
- Description:
- % Identity: 63.1
- Alignment Length: 179 - Location of Alignment in SEQ ID NO 216: from 2 to
176
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 217 - Ceres seq_id 1397132
- Location of start within SEQ ID NO 215: at 52 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 141
- gi No. 2827551
- Description:
- % Identity: 63.1 - Alignment Length: 179
- Location of Alignment in SEQ ID NO 217: from 1 to 159
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 218
- Ceres seq__id 1397133
- Location of start within SEQ ID NO 215: at 211 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 142
- gi No. 2827551
- Description: - % Identity: 63.1
- Alignment Length: 179
- Location of Alignment in SEQ ID NO 218: from 1 to 106 (Ba) Polypeptide Activities: Similar to meth CpG binding protein activities.
Maximum Length Sequence: related to: Clone IDs: 92204 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 219
- Ceres seq_id 1398004 - Alternative transcription start site(s) located in SEQ ID NO 219:
2,3,5,8,28
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 220
- Ceres seq_id 1398005
- Location of start within SEQ ID NO 219: at 68 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 143
- gi No. 4454037
- Description: - % Identity: 99.3
- Alignment Length: 151
- Location of Alignment in SEQ ID NO 220: from 1 to 151
(Ba) Polypeptide Activities: Similar to major latex protein activities.
Maximum Length Sequence: related to: Clone IDs: 98584
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 221
- Ceres seq_id 1399370
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 222
- Ceres seq_id 1399371
- Location of start within SEQ ID NO 221: at 3 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 144 - gi No. 4886285
- Description:
- % Identity: 28.8
- Alignment Length: 59
- Location of Alignment in SEQ ID NO 222: from 25 to 83 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 223
- Ceres seq_id 1399372
- Location of start within SEQ ID NO 221: at 45 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 145 - gi No. 4886285
- Description:
- % Identity: 28.8
- Alignment Length: 59
- Location of Alignment in SEQ ID NO 223: from 11 to 69
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 224
- Ceres seq_id 1399373 - Location of start within SEQ ID NO 221: at 60 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 224: at 25 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 14
- gi No. 4886285
- Description: - % Identity: 28.8
- Alignment Length: 59
- Location of Alignment in SEQ ID NO 224: from 6 to 64 (Ba) Polypeptide Activities: Similar to outer envelope membrane protein in choloroplast in pea activities.
Maximum Length Sequence: related to: Clone IDs:
107400 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 225 - Ceres seq_id 1425147
- Alternative transcription start site(s) located in SEQ ID NO 225:
20,31,49,58,80 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 226 - Ceres seq_id 1425148
- Location of start within SEQ ID NO 225: at 85 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 147
- gi No. 3510256
- Description: - % Identity: 37.8
- Alignment Length: 158
- Location of Alignment in SEQ ID NO 226: from 1 to 155 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 227
- Ceres seq_id 1425149
- Location of start within SEQ ID NO 225: at 241 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 148
- gi No. 3510256 - Description:
- % Identity: 37.8
- Alignment !_.ength: 158
- Location of Alignment in SEQ ID NO 227: from 1 to 103
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
11073 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 228 - Ceres seq_id 1441102
- Alternative transcription start site(s) located in SEQ ID NO 228:
2, 3, 4, 5, 8, 10, 16, 22, 51, 69, 388 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 229
- Ceres seq_id 1441103
- Location of start within SEQ ID NO 228: at 1 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 149
- gi No. 4337175
- Description: - % Identity: 100
- Alignment Length: 179
- Location of Alignment in SEQ ID NO 229: from 19 to 197 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 230
- Ceres seq_id 1441104
- Location of start within SEQ ID NO 228: at 55 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 150
- gi No. 4337175 - Description:
- % Identity: 100
- Alignment Length: 179
- Location of Alignment in SEQ ID NO 230: from 1 to 179 B ) Polypeptide Sequence
- Pat. Appln. SEQ ID :rø 231
- Ceres seq_id 1441105
- Location of start within SEQ ID NO 228 at 94 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 151 - gi No. 4337175
- Description:
- % Identity: 100
- Alignment Length: 179
- Location of Alignment in SEQ ID NO 231: from 1 to 166
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs:
267227 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 232 - Ceres seq id 1447480 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 233 - Ceres seq__id 1447481
- Location of start within SEQ ID NO 232: at 52 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 152
- gi No. 3510256
- Description:
- % Identity: 54 - Alignment Length: 50
- Location of Alignment in SEQ ID NO 233: from 77 to 126
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 234
- Ceres seq_id 1447482
- Location of start within SEQ ID NO 232: at 208 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 153
- gi No. 3510256
- Description: - % Identity: 54
- Alignment Length: 50
- Location of Alignment in SEQ ID NO 234: from 25 to 74 (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
268712 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 235
- Ceres seq_id 1447577
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 236
- Ceres seq_id 1447578 - Location of start within SEQ ID NO 235: at 2 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 154 - gi No. 5080769
- Description:
- % Identity: 100
- Alignment Length: 17
- Location of Alignment in SEQ ID NO 236: from 16 to 32
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 237
- Ceres seq_id 1447579 - Location of start within SEQ ID NO 235: at 165 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 155
- gi No. 5080769
- Description:
- % Identity: 91.5
- Alignment Length: 153 - Location of Alignment in SEQ ID NO 237: from 1 to
115
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 238 - Ceres seq_id 1447580
- Location of start within SEQ ID NO 235: at 298 nt .
(Ba) Polypeptide Activities: Similar to hydroxyproline-rich glycoprotein activities.
Maximum Length Sequence: related to: Clone IDs: 94821
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 239
- Ceres seq_id 1447922
- Alternative transcription start site(s) located in SEQ ID NO 239:
12,16
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 240 - Ceres seq_id 1447923
- Location of start within SEQ ID NO 239: at 81 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 156
- gi No. 3510256
- Description:
- % Identity: 37.8
- Alignment Length: 158 - Location of Alignment in SEQ ID NO 240: from 1 to
155
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 241 - Ceres seq_id 1447924
- Location of start within SEQ ID NO 239: at 237 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 157
- gi No. 3510256
- Description:
- % Identity: 37.8 - Alignment Length: 158
- Location of Alignment in SEQ ID NO 241: from 1 to 103
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 20539
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 242
- Ceres seq_id 1448012
- Alternative transcription start site(s) located in SEQ ID NO 242:
-30,-6
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 243 - Ceres seq_id 1448013
- Location of start within SEQ ID NO 242: at 79 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Ribosomal protein S16
- Location within SEQ ID NO 243: from 9 to 70 aa . (Dp) Related Amino Acid Sequences
- Alignment No. 158
- gi No. 3096931
- Description:
- % Identity: 57.5
- Alignment Length: 113
- Location of Alignment in SEQ ID NO 243: from 1 to 112
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 244
- Ceres seq_id 1448014
- Location of start within SEQ ID NO 242: at 139 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S16
- Location within SEQ ID NO 244: from 1 to 50 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 159
- gi No. 3096931
- Description: - % Identity: 57.5
- Alignment Length: 113
- Location of Alignment in SEQ ID NO 244: from 1 to 92 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 245
- Ceres seq_id 1448015
- Location of start within SEQ ID NO 242: at 232 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 160
- gi No. 3096931 - Description:
- % Identity: 57.5
- Alignment Length: 113
- Location of Alignment in SEQ ID NO 245: from 1 to 61
Maximum Length Sequence: related to: Clone IDs: 34091 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 246 - Ceres seq_id 1448135
- Alternative transcription start site(s) located in SEQ ID NO 246:
-1
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 247
- Ceres seq_id 1448136
- Location of start within SEQ ID NO 246: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 248
- Ceres seq_id 1448137
- Location of start within SEQ ID NO 246: at 68 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein S14p/S29e
- Location within SEQ ID NO 248: from 3 to 54 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 161
- gi No. 4506717
- Description:
- % Identity: 72.2 - Alignment Length: 54
- Location of Alignment in SEQ ID NO 248: from 1 to 54
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 249
- Ceres seq_id 1448138
- Location of start within SEQ ID NO 246: at 85 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to: Clone IDs: 39285 Public Genomic DNA: gi No: 4406776 Predicted Exons: SINGLE 61584 ... 61895 GENBANK SINGLE 61584 ... 61895 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 250
- Ceres seq_id 1448185 - Alternative transcription start site(s) located in SEQ ID NO 250:
-36,-18,-17,16,19
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 251
- Ceres seq_id 1448186
- Location of start within SEQ ID NO 250: at 41 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 162
- gi No. 4406787
- Description: - % Identity: 100
- Alignment Length: 103
- Location of Alignment in SEQ ID NO 251: from 1 to 103 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 252
- Ceres seq_id 144818"
- Location of start within SEQ ID NO 250: at 68 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 163
- gi No. 4406787 - Description:
- % Identity: 100
- Alignment Length: 103
- Location of Alignment in SEQ ID NO 252: from 1 to
94
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 253
- Ceres seq_id 1448188
- Location of start within SEQ ID NO 250: at 89 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 164 - gi No. 4406787
- Description: - % Identity: 100
- Alignment Length: 103
- Location of Alignment in SEQ ID NO 253: from 1 to 87 (Ba) Polypeptide Activities: Similar to NADH dehydrogenase protein activities
Maximum Length Sequence: related to: Clone IDs:
99119 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 254 - Ceres seq id 1450875
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 255
- Ceres seq_id 1450876
- Location of start within SEQ ID NO 254: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 255: at 26 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- ATPases associated with various cellular activities (AAA) - Location within SEQ ID NO 255: from 391 to 598 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 165 - gi No. 4309734
- Description:
- % Identity: 86
- Alignment Length: 633
- Location of Alignment in SEQ ID NO 255: from 9 to 634
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 256
- Ceres seq_id 1450877 - Location of start within SEQ ID NO 254: at 14 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 256: at 22 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - ATPases associated with various cellular activities (AAA)
- Location within SEQ ID NO 256: from 387 to 594 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 166
- gi No. 4309734
- Description: - % Identity: 86
- Alignment Length: 633
- Location of Alignment in SEQ ID NO 256: from 5 to 630 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 257
- Ceres seq_id 1450878
- Location of start within SEQ ID NO 254: at 68 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- ATPases associated with various cellular activities (AAA)
- Location within SEQ ID NO 257: from 369 to 576 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 167
- gi No. 4309734 - Description:
- % Identity: 86
- Alignment Length: 633
- Location of Alignment in SEQ ID NO 257: from 1 to
612
Maximum Length Sequence: related to: Clone IDs:
269321 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 258
- Ceres seq id 1459191
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 259
- Ceres seq_id 1459192
- Location of start within SEQ ID NO 258: at 1 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 168
- gi No. 4490728
- Description: - % Identity: 100
- Alignment Length: 17
- Location of Alignment in SEQ ID NO 259: from 21 o 37 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 260
- Ceres seq_id 1459193
- Location of start within SEQ ID NO 258: at 3 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 169
- gi No. 4490728 - Description:
- % Identity: 85.9
- Alignment Length: 85
- Location of Alignment in SEQ ID NO 260: from 37 to 110
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 8446 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 261 - Ceres seq_id 1461848
- Alternative transcription start site(s) located in SEQ ID NO 261:
-3, 6, 7, 11, 31, 32, 34, 62, 63, 69, 70, 71, 97 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 262
- Ceres seq_id 1461849
- Location of start within SEQ ID NO 261: at 113 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 262: at 36 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - MAPEG family - Location within SEQ ID NO 262: from 59 to 136 aa . (Dp) Related Amino Acid Sequences
- Alignment No. 170
- gi No. 4758714
- Description: - % Identity: 41.9
- Alignment Length: 131
- Location of Alignment in SEQ ID NO 262: from 8 to 136 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 263
- Ceres seq_id 1461850
- Location of start within SEQ ID NO 261: at 197 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- MAPEG family
- Location within SEQ ID NO 263: from 31 to 108 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 171
- gi No. 4758714
- Description:
- % Identity: 41.9 - Alignment Length: 131
- Location of Alignment in SEQ ID NO 263: from 1 to 108
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 264
- Ceres seq_id 1461851
- Location of start within SEQ ID NO 261: at 329 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 264: at 22 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- MAPEG family
- Location within SEQ ID NO 264: from 1 to 64 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 172
- gi No. 4758714
- Description: - % Identity: 41.9
- Alignment Length: 131
- Location of Alignment in SEQ ID NO 264: from 1 to 64 Maximum Length Sequence: related to: Clone I Ds :
25093 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 265 - Ceres seq_id 1472772
- Alternative transcription start site(s) located in SEQ ID NO 265:
-1,3 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 266
- Ceres seq_id 1472773
- Location of start within SEQ ID NO 265: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 266: at 32 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family - Location within SEQ ID NO 266: from 45 to 108 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 173
- gi No. 3062791 - Description:
- % Identity: 72.2
- Alignment Length: 90
- Location of Alignment in SEQ ID NO 266: from 21 to 110
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 267
- Ceres seq_id 1472774
- Location of start within SEQ ID NO 265: at 27 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 267: at 24 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Plant lipid transfer protein family
- Location within SEQ ID NO 267: from 37 to 100 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 174 - gi No. 3062791
- Description:
- % Identity: 72.2
- Alignment Length: 90
- Location of Alignment in SEQ ID NO 267: from 13 to 102 Maximum Length Sequence: related to: Clone IDs: 42300 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 268
- Ceres seq_id 1533352
- Alternative transcription start site(s) located in SEQ ID NO 268: 17
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 269
- Ceres seq_id 1533353 - Location of start within SEQ ID NO 268: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- haloacid dehalogenase-like hydrolase - Location within SEQ ID NO 269: from 82 to 266 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 175
- gi No. 3913203 - Description:
- % Identity: 32.8
- Alignment Length: 196
- Location of Alignment in SEQ ID NO 269: from 81 to 266
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 270
- Ceres seq_id 1533354
- Location of start within SEQ ID NO 268: at 25 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- haloacid dehalogenase-like hydrolase
- Location within SEQ ID NO 270: from 74 to 258 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 176
- gi No. 3913203
- Description: - % Identity: 32.8
- Alignment Length: 196
- Location of Alignment in SEQ ID NO 270: from 73 to 258 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 271 - Ceres seq_id 1533355
- Location of start within SEQ ID NO 268: at 265 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- haloacid dehalogenase-like hydrolase
- Location within SEQ ID NO 271: from 1 to 178 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 177
- gi No. 3913203
- Description:
- % Identity: 32.8
- Alignment Length: 196 - Location of Alignment in SEQ ID NO 271: from 1 to
178
Maximum Length Sequence: related to: Clone IDs:
158412 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 272
- Ceres seq_id 1534544
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 273
- Ceres seq_id 1534545 - Location of start within SEQ ID NO 272: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 178
- gi No. 2317676
- Description:
- % Identity: 37.2
- Alignment Length: 115 - Location of Alignment in SEQ ID NO 273: from 22 to 134
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 274 - Ceres seq_id 1534546
- Location of start within SEQ ID NO 272: at 524 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 179 - gi No. 4836939
- Description:
- % Identity: 47.3
- Alignment Length: 150 - Location of Alignment in SEQ ID NO 274: from 19 to 166
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 275 - Ceres seq_id 1534547
- Location of start within SEQ ID NO 272: at 815 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 180
- gi No. 4836939
- Description:
- % Identity: 47.3 - Alignment Length: 150
- Location of Alignment in SEQ ID NO 275: from 1 to 69
(Ba) Polypeptide Activities: Similar to calcium independent phrophospholipase A2 protein activities, and acy-protein thioesterase activities.
Maximum Length Sequence: related to: Clone IDs:
108109 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 276 - Ceres seq_id 1567172
- Alternative transcription start site(s) located in SEQ ID NO 276:
22 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 277
- Ceres seq_id 1567173
- Location of start within SEQ ID NO 276: at 152 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 181
- gi No. 1076301 - Description: CONSTANS protein Arabidopsis thaliana >gi | 1161514 | emb | CAA64407 | (X94937 CONSTANS protein [Arabidopsis thaliana]
- % Identity: 49.2
- Alignment Length: 63
- Location of Alignment in SEQ ID NO 277: from 12 to 74
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 27.
- Ceres seq_id 1567174
- Location of start within SEQ ID NO 276: at 155 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 182
- gi No. 1076301
- Description: CONSTANS protein Arabidopsis thaliana >gi I 1161514 I emb I CAA64407 I (X94937 CONSTANS protein
[Arabidopsis thaliana]
- % Identity: 49.2
- Alignment Length: 63
- Location of Alignment in SEQ ID NO 278: from 11 to 73
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 279
- Ceres seq_id 1567175
- Location of start within SEQ ID NO 276: at 443 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 183
- gi No. 1076301
- Description: CONSTANS protein Arabidopsis thaliana >gi | 1161514 | emb | CAA64407 | (X94937 CONSTANS protein [Arabidopsis thaliana] - % Identity: 67.4
- Alignment Length: 43
- Location of Alignment in SEQ ID NO 279 from 261 to 303 Maximum Length Sequence: related to: Clone IDs:
168 Public Genomic DNA: gi No: 4895213
Predicted Exons: INIT 22484 ... 22368 OCKHAMG-CDS TERM 21760 ... 21704 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 280 - Ceres seq_id 1567535
- Alternative transcription start site(s) located in SEQ ID NO 280:
12,22,23,25,28,36,68 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 281
- Ceres seq_id 1567536
- Location of start within SEQ ID NO 280: at 104 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 184
- gi No. 1351365 - Description: UBIQUINOL-CYTOCHROME C REDUCTASE
COMPLEX 6.7 KD PROTEIN (CR6) >gi | 2130002 | pir || S68969 ubiquinol--cytochrome-c reductase (EC 1.10.2.2) - potato >gi| 633683|emb|CAA57768 I (X82325) cytochrome c reductase subunit [Solanum tuberosum] - % Identity: 52.6
- Alignment Length: 58
- Location of Alignment in SEQ ID NO 281: from 2 to 57 Maximum Length Sequence: related to: Clone IDs:
21305 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 282
- Ceres seq_id 1569689
- Alternative transcription start site(s) located in SEQ ID NO 282:
28,29,49
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 283
- Ceres seq_id 1569690
- Location of start within SEQ ID NO 282: at 1 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 283: at 32 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 284
- Ceres seq_id 1569691
- Location of start within SEQ ID NO 282: at 92 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 185 - gi No. 2191138
- Description: (AF007269) A_IG002N01.18 gene product [Arabidopsis thaliana]
- % Identity: 19.5
- Alignment Length: 87 - Location of Alignment in SEQ ID NO 284: from 3 to
83
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 285 - Ceres seq_id 1569692
- Location of start within SEQ ID NO 282: at 248 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 186
- gi No. 2191138
- Description: (AF007269) A_IG002N01.18 gene product [Arabidopsis thaliana] - % Identity: 19.5
- Alignment Length: 87
- Location of Alignment in SEQ ID NO 285: from 1 to 31 (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 41988 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 286
- Ceres seq_id 1571042 - Alternative transcription start site(s) located in SEQ ID NO 286:
-1,2,3,4,7
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 287
- Ceres seq id 1571043 - Location of start within SEQ ID NO 286: at 63 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 187
- gi No. 2129641
- Description: major latex protein type 1 - Arabidopsis thaliana >gi | 1107493 | emb | CAA63026 | (X91960) major latex protein typel [Arabidopsis thaliana]
- % Identity: 71.3
- Alignment Length: 150
- Location of Alignment in SEQ ID NO 287: from 1 to 150
Maximum Length Sequence: related to: Clone IDs: 16143 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 288
- Ceres seq_id 1571079
- Alternative transcription start site(s) located in SEQ ID NO 288: -5,37,86,341,350
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 289
- Ceres seq_id 1571080 - Location of start within SEQ ID NO 288: at 51 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Pathogenesis-related protein Bet v I family - Location within SEQ ID NO 289: from 5 to 155 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 188
- gi No. 1321731 - Description: (Z72439) major allergen Cor a 1
[Corylus avellana]
- % Identity: 35.7
- Alignment Length: 159
- Location of Alignment in SEQ ID NO 289: from 5 to 155
Maximum Length Sequence: related to: Clone IDs: 42101
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 290
- Ceres seq id 1572097
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 291
- Ceres seq_id 1572098
- Location of start within SEQ ID NO 290: at 63 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Adhesion lipoprotein
- Location within SEQ ID NO 291: from 118 to 191 aa ,
(Dp) Related Amino Acid Sequences
- Alignment No. 189
- gi No. 2129641
- Description: major latex protein type 1 - Arabidopsis thaliana >gi | 1107493 I emb | CAA63026 | (X91960) major latex protein typel [Arabidopsis thaliana]
- % Identity: 69.5
- Alignment Length: 154
- Location of Alignment in SEQ ID NO 291: from 1 to 154
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 292
- Ceres seq_id 1572099 - Location of start within SEQ ID NO 290: at 336 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Adhesion lipoprotein - Location within SEQ ID NO 292: from 27 to 100 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 190
- gi No. 2129641 - Description: major latex protein type 1 -
Arabidopsis thaliana >gi | 1107493 | emb I CAA63026 | (X91960) major latex protein typel [Arabidopsis thaliana]
- % Identity: 69.5
- Alignment Length: 154 - Location of Alignment in SEQ ID NO 292: from 1 to
63
Maximum Length Sequence: related to: Clone IDs: 27643 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 293
- Ceres seq_id 1572890
- Alternative transcription start site(s) located in SEQ ID NO 293:
-10
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 294 - Ceres seq_id 1572891
- Location of start within SEQ ID NO 293: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Photosystem I psaG / psaK
- Location within SEQ ID NO 294: from 71 to 151 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 191 - gi No. 3885511
- Description: (AF084200) similar to PSI-K subunit of photosystem I from barley [Medicago sativa]
- % Identity: 80.3
- Alignment Length: 128 - Location of Alignment in SEQ ID NO 294: from 22 to 148
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 295 - Ceres seq_id 1572892
- Location of start within SEQ ID NO 293: at 64 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Photosystem I psaG / psaK
- Location within SEQ ID NO 295: from 50 to 130 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 192 - gi No. 3885511
- Description: (AF084200) similar to PSI-K subunit of photosystem I from barley [Medicago sativa]
- % Identity: 80.3
- Alignment Length: 128 - Location of Alignment in SEQ ID NO 295: from 1 to
127
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 296 - Ceres seq_id 1572893
- Location of start within SEQ ID NO 293: at 76 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Photosystem I psaG / psaK - Location within SEQ ID NO 296: from 46 to 126 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 193
- gi No. 3885511 - Description: (AF084200) similar to PSI-K subunit of photosystem I from barley [Medicago sativa]
- % Identity: SO.3
- Alignment Length: 128
- Location of Alignment in SEQ ID NO 296: from i to 123
Maximum Length Sequence: related to: Clone IDs: 33027
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 297
- Ceres seq_id 1573606
- Alternative transcription start site(s) located in SEQ ID NO 297:
7,8,13
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 298 - Ceres seq_id 1573607
- Location of start within SEQ ID NO 297: at 56 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 298: at 19 aa . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Pollen proteins Ole e I family
- Location within SEQ ID NO 298: from 32 to 131 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 194
- gi No. 4584110
- Description: (AJ133639) SAH7 protein [Arabidopsis thaliana] - % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 298: from 1 to 163 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 299 - Ceres seq_id 1573608
- Location of start within SEQ ID NO 297: at 71 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 299: at 14 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Pollen proteins Ole e I family
- Location within SEQ ID NO 299: from 27 to 126 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 195
- gi No. 4584110
- Description: (AJ133639) SAH7 protein [Arabidopsis thaliana]
- % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 299: from 1 to 158
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 300
- Ceres seq_id 1573609
- Location of start within SEQ ID NO 297: at 107 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Pollen proteins Ole e I family
- Location within SEQ ID NO 300: from 15 to 114 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 196
- gi No. 4584110
- Description: (AJ133639) SAH7 protein [Arabidopsis thaliana]
- % Identity: 48.5
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 300: from 1 to 146
Maximum Length Sequence: related to: Clone IDs: 31422 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 301
- Ceres seq id 1573861
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 302 - Ceres seq_id 1573862
- Location of start within SEQ ID NO 301: at 67 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 197
- gi No. 2191138
- Description: (AF007269) A_IG002N01.18 gene product [Arabidopsis thaliana]
- % Identity: 28.1
- Alignment Length: 160
- Location of Alignment in SEQ ID NO 302: from 3 to 156
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 303
- Ceres seq_id 1573863
- Location of start within SEQ ID NO 301: at 223 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 198 - gi No. 2191138
- Description: (AF007269) A_IG002N01.18 gene product [Arabidopsis thaliana]
- % Identity: 28.1
- Alignment Length: 160 - Location of Alignment in SEQ ID NO 303: from 1 to
104
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 40916 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 304
- Ceres seq id 1574093
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 305
- Ceres seq_id 1574094
- Location of start within SEQ ID NO 304: at 47 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) - Zinc finger, C3HC4 type (RING finger)
- Location within SEQ ID NO 305: from 152 to 192 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 199
- gi No. 3790593
- Description: (AF079185) RING-H2 finger protein RHYla [Arabidopsis thaliana]
- % Identity: 55.1
- Alignment Length: 49
- Location of Alignment in SEQ ID NO 305: from 14! to 196
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 306
- Ceres seq_id 1574095
- Location of start within SEQ ID NO 304 it 56 nt,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
- Zinc finger, C3HC4 type (RING finger)
- Location within SEQ ID NO 306: from 149 to 189 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 200
- gi No. 3790593
- Description: (AF079185) RING-H2 finger protein RHYla [Arabidopsis thaliana]
- % Identity: 55.1
- Alignment Length: 49
- Location of Alignment in SEQ ID NO 306: from 145 to 193
Maximum Length Sequence : related to: Clone IDs:
35447 Public Genomic DNA: gi No: 4263694 Predicted Exons: INIT 79640 .. 79806 GENBANK TERM 79888 .. 80164 GENBANK
INTR 79508 79806 OCKHAMG-CDNA INTR 79888 80309 OCKHAMG-CDNA
INIT 79640 79806 OCKHAMG-CDS TERM 79888 80164 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 307
- Ceres seq__id 1580388
- Alternative transcription start site(s) located in SEQ ID NO 307: 2,3,4,5,6,7,63,94
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 308
- Ceres seq_id 1580389 - Location of start within SEQ ID NO 307: at 133 n .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 308: at 27 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Cystatin domain
- Location within SEQ ID NO 308: from 87 to 141 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 201
- gi No. 2204077
- Description: (D85623) extracellular insoluble cystatin [Daucus carota]
- % Identity: 44.9 - Alignment Length: 136
- Location of Alignment in SEQ ID NO 308: from 6 to 141
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 309
- Ceres seq_id 1580390
- Location of start within SEQ ID NO 307: at 142 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 309: at 24 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Cystatin domain
- Location within SEQ ID NO 309: from 84 to 138 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 202
- gi No. 2204077
- Description: (D85623) extracellular insoluble cystatin [Daucus carota]
- % Identity: 44.9
- Alignment Length: 136
- Location of Alignment in SEQ ID NO 309: from 3 to 138
Maximum Length Sequence: related to: Clone IDs:
22677 Public Genomic DNA: gi No: 4972043 Predicted Exons: SINGLE 18935 19282 GENBANK
INTR 18856 19527 OCKHAMG-CDNA
SINGLE 18935 19282 OCKHAMG-CDS gi No: 4972077
Predicted Exons
INTR 60360 61031 OCKHAMG-CDNA
SINGLE 60439 60786 OCKHAMG-CDS gi No: 5748495
Predicted Exons
INTR 60360 61031 OCKHAMG-CDNA
SINGLE 60439 ... 60786 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 310
- Ceres seq_id 1582959
- Alternative transcription start site(s) located in SEQ ID NO 310:
2,5,6,7,58, 61
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 311
- Ceres seq_id 1582960
- Location of start within SEQ ID NO 310: at 80 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 311: at 19 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Dehydrins
- Location within SEQ ID NO 311: from 37 to 113 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 203
- gi No. 4972049
- Description: (AL078470) glycine-rich protein like [Arabidopsis thaliana]
- % Identity: 100
- Alignment Length: 115
- Location of Alignment in SEQ ID NO 311: from 1 to 115
Maximum Length Sequence: related to: Clone IDs:
15190
34118 Public Genomic DNA: gi No: 4582444
Predicted Exons:
INIT 39128 39157 GENBANK
INTR 39241 39388 GENBANK
INTR 39469 39640 GENBANK
INTR 39922 40108 GENBANK
TERM 40198 40413 GENBANK
INTR 39945 40108 OCKHAMG-CDNA
INTR 40198 40660 OCKHAMG-CDNA
INTR 39054 39157 OCKHAMG-CDNA
INTR 39241 39388 OCKHAMG-CDNA
INTR 39469 39640 OCKHAMG-CDNA
INTR 39922 40108 OCKHAMG-CDNA
INTR 40198 40626 OCKHAMG-CDNA
INIT 39128 39157 OCKHAMG-CDS
INTR 39241 39388 OCKHAMG-CDS
INTR 39469 39640 OCKHAMG-CDS
INTR 39922 40108 OCKHAMG-CDS
TERM 40198 40413 OCKHAMG-CDS
(Ac! cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 312
- Ceres seq_id 1663221
- Alternative transcription start site(s) located in SEQ ID NO 312:
-5,2,3,4, 5, 12, 40, 448
- Clone 15190 starts at 448 and ends at 1076 in cDNA.
- Clone 34118 starts at 1 and ends at 1042 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 313
- Ceres seq_id 1663222
- Location of start within SEQ ID NO 312 at 75 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 313: from 104 to li aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 204
- gi No. 133940 - Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 70851 Ipir I I R3XL3A ribosomal protein S3a - African clawed frog >gi| 65091 | emb | CAA40592 | (X57322) ribosomal protein Sla [Xenopus laevis] - % Identity: 80.1
- Alignment Length: 231
- Location of Alignment in SEQ ID NO 313: from 1 to 228 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 314
- Ceres seq_id 1663223
- Location of start within SEQ ID NO 312: at 204 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 314: from 61 to 145 aa . (Dp) Related Amino Acid Sequences
- Alignment No. 205
- gi No. 133940
- Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 70851 I pir I | R3XL3A ribosomal protein S3a - African clawed frog >gi | 65091 | emb | CAA40592 | (X57322) ribosomal protein Sla [Xenopus laevis]
- % Identity: 80.1
- Alignment Length: 231
- Location of Alignment in SEQ ID NO 314: from 1 to 185
Maximum Length Sequence: related to: Clone IDs: 3996 2749 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 315
- Ceres seq_id 1663275 - Alternative transcription start site(s) located in SEQ ID NO 315:
3,4,5, 6,7,8, 9,15
- Clone 3996 starts at 1 and ends at 484 in cDNA.
- Clone 2749 starts at 7 and ends at 488 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 316
- Ceres seq_id 1663276
- Location of start within SEQ ID NO 315: at 75 nt (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S14p/S29e
- Location within SEQ ID NO 316: from 3 to 54 aa ,
Dp) Related Amino Acid Sequences
- Alignment No. 206
- gi No. 4506717
- Description: ref I NP_001023.1 | pRPS29 | ribosomal protein S29 >gi 1266972 |sp| P30054 |RS29_HUMAN 40S RIBOSOMAL PROTEIN S29 >gi I 631884 |pir| IS30298 ribosomal protein S29 - rat >gi I 1362934 Ipir I I S55919 ribosomal protein S29 - human protein S29 [Homo sapiens]
- % Identity: 72.2
- Alignment Length: 54
- Location of Alignment in SEQ ID NO 316: from 1 to
54 B ) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 317
- Ceres seq_id 1663277
- Location of start within SEQ ID NO 315: at 92 nt,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to: Clone IDs:
114940 25068 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NC 318 - Ceres seq_id 1665304
- Alternative transcription start site(s) located in SEQ ID NO 318:
-8,-3,-1,2,3,4,8, 17,251
- Clone 114940 starts at 1 and ends at 743 in cDNA. - Clone 25068 starts at 4 and ends at 760 in cDNA.
IB) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 319
- Ceres seq_id 1665305
- Location of start within SEQ ID NO 31! at 63 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 207
- gi No. 2129641 - Description: major latex protein type 1 - Arabidopsis thaliana >gi I 1107493 | emb I CAA63026 | (X91960) major latex protein typel [Arabidopsis thaliana]
- % Identity: 71.3 - Alignment Length: 150
- Location of Alignment in SEQ ID NO 319: from 1 to 150
Maximum Length Sequence: related to: Clone IDs:
94673 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 320 - Ceres seq_id 1709970
- Alternative transcription start site(s) located in SEQ ID NO 320:
-2, -1,11, 41, 42, 43, 44, 45, 6, 47, 48, 51 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 321
- Ceres seq_id 1709971
- Location of start within SEQ ID NO 320: at 276 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 208
- gi No. 2961300 - Description: (AJ225027) ribosomal protein L24
[Cicer arietinum]
- % Identity: 86.2
- Alignment Length: 160
- Location of Alignment in SEQ ID NO 321: from 1 to 107
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 322
- Ceres seq_id 1709972 - Location of start within SEQ ID NO 320: at 424 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence : related to: Clone IDs:
112835 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 323 - Ceres seq_id 1711273
- Alternative transcription start site(s) located in SEQ ID NO 323:
2,28,30,33,56, 62,235
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 324
- Ceres seq_id 1711274
- Location of start within SEQ ID NO 323: at 92 nt .
10
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Helix-turn-helix
- Location within SEQ ID NO 324: from 87 to 141 aa . i <=.
(Dp) Related Amino Acid Sequences
- Alignment No. 209
- gi No. 1632831
- Description: (Z49698) orf [Ricinus communis] 20 - % Identity: 81
- Alignment Length: 142
- Location of Alignment in SEQ ID NO 324: from 1 to 142
25 Maximum Length Sequence: related to: Clone IDs:
17878 (Ac) cDNA Polynucleotide Sequence 30 - Pat. Appln. SEQ ID NO 325
- Ceres seq_id 1715423
- Alternative transcription start site(s) located in SEQ ID NO 325:
2,4,7, 66
35
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 326
- Ceres seq_id 1715424
- Location of start within SEQ ID NO 325: at 25 nt .
40
(C) Nomination and Annotation of Domains within Predicted Polypeptide ( s )
(Dp) Related Amino Acid Sequences
- Alignment No. 210 45 - gi No. 4337175
- Description: (AC006416) ESTs gb|T20589, gb|T04648, gb|AA597906, gb|T04111, gb|R84l80, gbiR65428, gb|T44439, gb|T76570, gb|R90004, gb|T45020, gb|T42457, gb|T20921, gb|AA042762 and gb|AA720210 come from this gene.
50 [Arabidopsis thaliana]
- % Identity: 44.8 - Alignment Length: 67
- Location of Alignment in SEQ ID NO 326: from 15 to 81
|B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 327
- Ceres seq_id 1715425
- Location of start within SEQ ID NO 325: at 40 nt , (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 211
- gi No. 4337175 - Description: (AC006416) ESTs gb|T20589, gb|T04648, gb|AA597906, gb|T04111, gb|R84180, gb|R65428, gb|T44439, gb|T76570, gb|R90004, gb|T45020, gb|T42457, gb|T20921, gb|AA042762 and gb|AA72021C come from this gene. [Arabidopsis thaliana] - % Identity: 44.8
- Alignment Length: 67
- Location of Alignment in SEQ ID NO 327: from 10 to 76
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 328
- Ceres seq__id 1715426
- Location of start within SEQ ID NO 325: at 260 nt .
(C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp Related Amino Acid Sequences
- Alignment No. 212
- gi No. 4337175
- Description: (AC006416) ESTs gb|T20589, gb|T04648, gb|AA597906, gb|T04111, gb|R84180, gb|R65428, gb|T44439, gb|T76570, gb|R90004, gb|T45020, gb|T42457, gb|T20921, gb|AA042762 and gb|AA720210 come from this gene, [Arabidopsis thaliana]
- % Identity: 56.1
- Alignment Length: 57
- Location of Alignment in SEQ ID NO 328: from 5 to
61 (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 26744 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 329
- Ceres seq_id 1715962
- Alternative transcription start site(s) located in SEQ ID NO 329:
2, 7, 9, 10, 26, 28, 30, 31, 32, 38, 39, 42, 43, 47, 48, 194, 247
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 330 - Ceres seq_id 1715963
- Location of start within SEQ ID NO 329: at 87 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Ribosomal protein L6
- Location within SEQ ID NO 330: from 12 to 194 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 213 - gi No. 1710581
- Description: 60S RIBOSOMAL PROTEIN L9
>gi I 2129720 I pir I I S71255 ribosomal protein L9 - Arabidopsis thaliana >gi I 1107489 | emb I CAA63024 | (X91958) 60S ribosomal protein L9 [Arabidopsis thaliana] - % Identity: 93.3
- Alignment Length: 195
- Location of Alignment in SEQ ID NO 330: from 1 to 194 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 331
- Ceres seq_id 1715964
- Location of start within SEQ ID NO 329: at 114 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein L6
- Location within SEQ ID NO 331: from 3 to 185 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 214
- gi No. 1710581
- Description: 60S RIBOSOMAL PROTEIN L9
>gi 12129720 Ipir I I S71255 ribosomal protein L9 - Arabidopsis thaliana >gi | 1107489 I emb | CAA63024 | (X91958) 60S ribosomal protein L9 [Arabidopsis thaliana]
- % Identity: 93.3
- Alignment Length: 195
- Location of Alignment in SEQ ID NO 331: from 1 to 185 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 332
- Ceres seq_id 1715965
- Location of start within SEQ ID NO 329: at 369 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
- Ribosomal protein L6
- Location within SEQ ID NO 332: from 1 to 100 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 215
- gi No. 1710581
- Description: 60S RIBOSOMAL PROTEIN L9
>gϋ 2129720 Ipir I IS71255 ribosomal protein L9 - Arabidopsis thaiiana >gi | 1107489 I emb I CAA63024 | (X91958) 60S ribosomal prctein L9 [Arabidopsis thaliana]
- % Identity: 93.3
- Alignment Length: 195
- Location of Alignment in SEQ ID NO 332: from 1 ;o
100
Maximum Length Sequence related to:
Clone IDs: 41712
Public Genomic DNA: gi No: 4512656 Predicted Exons:
INIT 106774.. 106633 GENBANK
INTR 106277.. 106194 GENBANK
INTR 105920.. 105838 GENBANK
TERM 105749.. 105630 GENBANK
INTR 106841.. 106633 OCKHAMG- -CDNA
INTR 106277.. 106194 OCKHAMG- -CDNA
INTR 105920.. 105838 OCKHAMG- -CDNA
INTR 105749.. 105453 OCKHAMG- -CDNA
INIT 106774.. 106633 OCKHAMG- -CDS
INTR 106277.. 106194 OCKHAMG- -CDS
INTR 105920.. 105838 OCKHAMG- -CDS
TERM 105749.. 105630 OCKHAMG- -CDS gi No: 4559319
Predicted Exons :
INIT 10855 .. . 10714 GENBANK
INTR 10358 .. 10275 GENBANK
INTR 10001 .. 9919 GENBANK
TERM 9830 .. . 9711 GENBANK
INTR 10922 10714 OCKHAMG-CDNA INTR 10358 ... 10275 OCKHAMG-CDNA
INTR 10001 .. . 9919 OCKHAMG-CDNA
INTR 9830 .. . 9534 OCKHAMG-CDNA
INIT 10855 .. . 10714 OCKHAMG-CDS
INTR 10358 .. . 10275 OCKHAMG-CDS
INTR 10001 .. . 9919 OCKHAMG-CDS
TERM 9830 .. . 9711 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 333
- Ceres seq_id 1808584
- Alternative transcription start site(s) located in SEQ ID NO 333:
34
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 334
- Ceres seq_id 1808585
- Location of start within SEQ ID NO 333 at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Helix-turn-helix
- Location within SEQ ID NO 334: from 110 to 164 aa .
|Dp) Related Amino Acid Sequences
- Alignment No. 216
- gi No. 1632831
- Description: (Z49698) orf [Ricinus communis]
- % Identity: 81
- Alignment Length: 142
- Location of Alignment in SEQ ID NO 334: from 24 to 165
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 335
- Ceres seq_id 1808586
- Location of start within SEQ ID NO 333: at 70 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Helix-turn-helix
- Location within SEQ ID NO 335: from 87 to 141 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 217
- gi No. 1632831
- Description: (Z49698) orf [Ricinus communis]
- % Identity: 81
- Alignment Length: 142 - Location of Alignment in SEQ ID NO 335: from 1 to
142
Maximum Length Sequence: related to: Clone IDs:
42211 Public Genomic DNA: gi No: 4914400 Predicted Exons: INTR 90159 .. 89532 OCKHAMG-CDNA
SINGLE 90124 ... 89615 OCKHAMG-CDS gi No: 4938473 Predicted Exons:
SINGLE 2368 ... 1859 GENBANK
INTR 2403 1776 OCKHAMG-CDNA SINGLE 2368 ... 1859 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 336
- Ceres seq_id 1808591
- Alternative transcription start site(s) located in SEQ ID NO 336:
7,10
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 337 - Ceres seq_id 1808592
- Location of start within SEQ ID NO 336: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 337: at 36 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 218
- gi No. 4926823 - Description: (AC004135) T17H7.8 [Arabidopsis thaliana]
- % Identity: 46.1
- Alignment Length: 178
- Location of Alignment in SEQ ID NO 337: from 13 to 177
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 338
- Ceres seq_id 1808593
- Location of start within SEQ ID NO 336: at 38 nt - Location of Signal Peptide Cleavage Site within SEQ ID NO 338: at 24 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 219
- gi No. 4926823
- Description: (AC004135) T17H7.8 [Arabidopsis thaliana]
- % Identity: 46.1
- Alignment Length: 178
- Location of Alignment in SEQ ID NO 338: from 1 to 165
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 339
- Ceres seq_id 1808594
- Location of start within SEQ ID NO 336: at 164 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 220 - gi No. 4926823
- Description: (AC004135) T17H7.8 [Arabidopsis thaliana]
- % Identity: 46.1
- Alignment Length: 178 - Location of Alignment in SEQ ID NO 339: from 1 to
123
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 2217 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 340
- Ceres seq_id 1920563
- Alternative transcription start site(s) located in SEQ ID NO 340: 6
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 341
- Ceres seq_id 1920564 - Location of start within SEQ ID NO 340: at 1 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Oxidoreductase FAD/NAD-binding domain
- Location within SEQ ID NO 341: from 45 to 167 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 221
- gi No. 729477
- Description: FERREDOXIN—NADP REDUCTASE PRECURSOR (FNR) >gi|320548 Ipir I IA44974 ferredoxin— ADP+ reductase (EC
1.18.1.2) precursor - common ice plant >gi|167256 (M25528) ferredoxin-NADP+ reductase precursor (fnrA; EC 1.6.7.1) [Mesembryanthemum
- % Identity: 89.8 - Alignment Length: 197
- Location of Alignment in SEQ ID NO 341: from 1 to 197
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 342
- Ceres seq_id 1920565
- Location of start within SEQ ID NO 340: at 112 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Oxidoreductase FAD/NAD-binding domain
- Location within SEQ ID NO 342: from 8 to 130 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 222
- gi No. 729477
- Description: FERREDOXIN—NADP REDUCTASE PRECURSOR (FNR) >gi| 320548 |pir| IA44974 ferredoxin—NADP+ reductase (EC 1.18.1.2) precursor - common ice plant >gi 1167256 (M25528) ferredoxin-NADP+ reductase precursor (fnrA; EC 1.6.7.1) [Mesembryanthemum
- % Identity: 89.8
- Alignment Length: 197
- Location of Alignment in SEQ ID NO 342: from 1 to 160
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 343
- Ceres seq__id 1920566 - Location of start within SEQ ID NO 340: at 118 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Oxidoreductase FAD/NAD-binding domain - Location within SEQ ID NO 343: from 6 to 128 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 223
- gi No. 729477
- Description: FERREDOXIN— ADP REDUCTASE PRECURSOR (FNR) >gi| 320548 |pir| IA44974 ferredoxin--NADP+ reductase (EC 1.18.1.2) precursor - common ice plant >gi 1167256 (M25528) ferredoxin-NADP-t- reductase precursor (fnrA; EC 1.6.7.1) [Mesembryanthemum
- % Identity: 89.8
- Alignment Length: 197
- Location of Alignment in SEQ ID NO 343: from 1 to 158
Maximum Length Sequence related to:
Clone IDs:
13864
Public Genomic DNA: gi No: 4309719
Predicted Exons:
INIT 50987 . . 50773 GENBANK
INTR 49622 . . 49352 GENBANK
INTR 49257 . . 49162 GENBANK
INTR 48896 . . 48786 GENBANK
INTR 48686 . . 48377 GENBANK
INTR 48133 . . 48043 GENBANK
INTR 47924 . . 47591 GENBANK
INTR 47475 . . 47327 GENBANK
TERM 47084 . . 46550 GENBANK
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 344
- Ceres seq_id 1974419
- Alternative transcription start site(s) located in SEQ ID NO 344:
-5 B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 345
- Ceres seq_id 1974420
- Location of start within SEQ ID NO 344: at 81 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- ATPases associated with various cellular activities (AAA)
- Location within SEQ ID NO 345: from 454 to 664 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 224
- gi No. 4006905 - Description: (Z99708) ATPase-like protein [Arabidopsis thaliana]
- % Identity: 84.3
- Alignment Length: 633 - Location of Alignment in SEQ ID NO 345: from 72 to 700
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 346 - Ceres seq_id 1974421
- Location of start within SEQ ID NO 344: at 96 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - ATPases associated with various cellular activities (AAA)
- Location within SEQ ID NO 346: from 449 to 659 aa . (Dp) Related Amino Acid Sequences
- Alignment No. 225
- gi No. 4006905
- Description: (Z99708) ATPase-like protein [Arabidopsis thaliana] - % Identity: 84.3
- Alignment Length: 633
- Location of Alignment in SEQ ID NO 346: from 67 to 695 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 347
- Ceres seq_id 1974422
- Location of start within SEQ ID NO 344: at 141 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- ATPases associated with various cellular activities (AAA)
- Location within SEQ ID NO 347: from 434 to 644 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 226
- gi No. 4006905 - Description: (Z99708) ATPase-like protein
[Arabidopsis thaliana]
- % Identity: 84.3
- Alignment Length: 633
- Location of Alignment in SEQ ID NO 347: from 52 to 680 Maximum Length Sequence: related to: Clone IDs:
36333 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 348
- Ceres seq id 1975983
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 349
- Ceres seq_id 1975984
- Location of start within SEQ ID NO 348: at 90 n . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 227
- gi No. 3688432 - Description: (AJ011705) 40S ribosomal protein S10
[Lumbricus rubellus]
- % Identity: 55.3
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 349: from 32 to 192
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 350
- Ceres seq_id 1975985 - Location of start within SEQ ID NO 348: at 135 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 228
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 55.3 - Alignment Length: 164
- Location of Alignment in SEQ ID NO 350: from 17 to 177
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 351
- Ceres seq_id 1975986
- Location of start within SEQ ID NO 348: at 183 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 229
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein SIO [Lumbricus rubellus] - % Identity: 55.3
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 351: from 1 to 161
(Ba) Polypeptide Activities: Similar to glycine-rich RNA binding ABA inducible protein activities.
Maximum Length Sequence: related to: Clone IDs: 24587
41072 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 352
- Ceres seq_id 1976019 - Alternative transcription start site(s) located in SEQ ID NO 352: 13
- Clone 24587 starts at 13 and ends at in cDNA. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 353
- Ceres seq_id 1976020
- Location of start within SEQ ID NO 352: at 101 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 230
- gi No. 3688432 - Description: (AJ011705) 40S ribosomal protein S10
[Lumbricus rubellus]
- % Identity: 55.3
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 353: from 1 to 161
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 354
- Ceres seq_id 1976021 - Location of start within SEQ ID NO 352: at 239 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 231
- gi No. 3688432 O/00466
226
- Description: (AJ011705) 40S ribosomal protein SIO [Lumbricus rubellus]
- % Identity: 55.3
- Alignment Length: 164 - Location of Alignment in SEQ ID NO 354: from 1 to
115
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 355 - Ceres seq_id 1976022
- Location of start within SEQ ID NO 352: at 287 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 232
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein SIO [Lumbricus rubellus] - % Identity: 55.3
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 355: from 1 to 99 (Ba) Polypeptide Activities: Extensin like protein activities and glycine rich protein activities.
Maximum Length Sequence: related to: Clone IDs:
117263 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 356
- Ceres seq_id 1976673 - Alternative transcription start site(s) located in SEQ ID NO 356:
-46,2,3, 6,7
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 357
- Ceres seq_id 1976674
- Location of start within SEQ ID NO 356: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 357: at 34 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S21
- Location within SEQ ID NO 357: from 106 to 155 aa. (Dp) Related Amino Acid Sequences Alignment No. 233 gi No. 1710750 Description: 30S RIBOSOMAL PROTEIN S21 (BS-B)
>gi|i 30381 4 |dbj |BAA12470| (D84432) YqeX [Bacillus subtilis] >gϋi89006 3|dbj |BAA12082| (D83717 YqeX [Bacillus subtilis] >gi|263498 7 |emb|CAB14483| (Z99117. ribosomal protein S21 [Bacillus subtilis]
- % Identity: 38.5
- Alignment Length: 52
- Location of Alignment in SEQ ID NO 357: from 106 to 157
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 358
- Ceres seq_id 1976675
- Location of start within SEQ ID NO 356: at 48 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 358: at 19 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S21
- Location within SEQ ID NO 358: from 91 to 140 aa ,
(Dp) Related Amino Acid Sequences
- Alignment No. 234
- gi No. 1710750
- Description: 30S RIBOSOMAL PROTEIN S21 (BS-B)
>gi 113 03814 dbj IBAA12470 I (D84432) YqeX [Bacillus subtilis] >gi I 1890063 dbj IBAA12082 (D83717) YqeX [Bacillus subtilis]
>gi|2634987 emb|CAB14483 (Z99117) ribosomal protein S21 [Bacillus subtilis]
- % Identity: 38.5
- Alignment Length: 52
- Location of Alignment in SEQ ID NO 358: from 91 to 142
\B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 359
- Ceres seq_id 1976676
- Location of start within SEQ ID NO 356; at 192 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S21
- Location within SEQ ID NO 359: from 43 to 92 aa ,
(Dp) Related Amino Acid Sequences
- Alignment No. 235
- gi No. 1710750 - Description: 30S RIBOSOMAL PROTEIN S21 (BS-B) >gi| 1303814 | dbj IBAA12470 (D84432) YqeX [Bacillus subtilis] >gi 11890063 I dbj IBAA12082 (D83717) YqeX [Bacillus subtilis] >gi I 2634987 | emb | CAB14483 (Z99117) ribosomal protein S21 [Bacillus subtilis]
- % Identity: 38.5
- Alignment Length: 52
- Location of Alignment in SEQ ID NO 359: from 43 to 94
Maximum Length Sequence: related to: Clone IDs:
42333 Public Genomic DNA: gi No: 6041810 Predicted Exons: INTR 93582 . 94052 OCKHAMG- -CDNA INTR 94169 . 94771 OCKHAMG--CDNA
INIT 93630 . 94052 OCKHAMG- -CDS
TERM 94169 . 94687 OCKHAMG--CDS gi No: 6091711 Predicted Exons :
INTR 60479 . 60949 OCKHAMG- -CDNA
INTR 61066 . 61668 OCKHAMG--CDNA
INIT 60527 . 60949 OCKHAMG- -CDS
TERM 61066 . 61584 OCKHAMG--CDS gi No: 6102641 Predicted Exons :
INTR 52165 . 52635 OCKHAMG- -CDNA
INTR 52752 . 53354 OCKHAMG--CDNA
INIT 52213 . 52635 OCKHAMG- -CDS
TERM 52752 . 53270 OCKHAMG--CDS gi No: 6453849 Predicted Exons:
INTR 59432 . 58964 OCKHAMG- -CDNA
INTR 58847 . 58243 OCKHAMG--CDNA
INIT 59386 ... 58964 OCKHAMG-CDS TERM 58847 ... 58329 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 360
- Ceres seq id 2025186
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 361
- Ceres seq_id 2025187 - Location of start within SEQ ID NO 360: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - D-isomer specific 2-hydroxyacid dehydrogenases
- Location within SEQ ID NO 361: from 93 to 295 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 236 - gi No. 5458864
- Description: (AJ248287) GLYCERATE DEHYDROGENASE [Pyrococcus abyssi]
- % Identity: 42.8
- Alignment Length: 299 - Location of Alignment in SEQ ID NO 361: from 36 to 322
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 362 - Ceres seq_id 2025188
- Location of start within SEQ ID NO 360: at 49 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - D-isomer specific 2-hydroxyacid dehydrogenases
- Location within SEQ ID NO 362: from 77 to 279 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 237 - gi No. 5458864
- Description: (AJ248287) GLYCERATE DEHYDROGENASE [Pyrococcus abyssi]
- % Identity: 42.8
- Alignment Length: 299 - Location of Alignment in SEQ ID NO 362: from 20 to 306
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 363 - Ceres seq_id 2025189
- Location of start within SEQ ID NO 360: at 70 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - D-isomer specific 2-hydroxyacid dehydrogenases
- Location within SEQ ID NO 363: from 70 to 272 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 238 - gi No. 5458864 - Description: IAJ248287' GLYCERATE DEHYDROGENASE [Pyrococcus abyssi]
% Identity: 42.8
Alignment Length: 299
Location of Alignment in SEQ ID NO 363 from 13 to 299
Maximum Length Sequence: related to: Clone IDs:
267004 Public Genomic DNA: gi No: 2924730 Predicted Exons: INTR 8331 . 8882 OCKHAMG-CDNA
SINGLE 8366 ... 8686 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 364 - Ceres seq_id 2025372
- Alternative transcription start site(s) located in SEQ ID NO 364:
21
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 365
- Ceres seq_id 2025373
- Location of start within SEQ ID NO 364: at 1 nt , (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 239
- gi No. 132825 - Description: 50S RIBOSOMAL PROTEIN CL25,
CHLOROPLAST PRECURSOR >gi | 71308 | pir | | R5PM25 ribosomal protein
PsCL25 precursor, chloroplast - garden pea
>gi|20877 | emb I CAA32187 | (X14022) PsCL25 ribosomal preprotein
(AA -30 to 74) [Pisum sativum] - % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 365: from 14 to 95 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 366
- Ceres seq_id 2025374
- Location of start within SEQ ID NO 364: at 37 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 366: at 16 aa. (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 240
- gi No. 132825
- Description: 50S RIBOSOMAL PROTEIN CL25, CHLOROPLAST PRECURSOR >gi I 71308 | pir | | R5PM25 ribosomal protein PsCL25 precursor, chloroplast - garden pea
>gi|20877 | emb | CAA32187 | (X14022) PsCL25 ribosomal preprotein (AA -30 to 74) [Pisum sativum]
- % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 366: from 2 to 83
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 367
- Ceres seq_id 2025375
- Location of start within SEQ ID NO 364: at 142 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 241
- gi No. 132825
- Description: 50S RIBOSOMAL PROTEIN CL25, CHLOROPLAST PRECURSOR >gi I 71308 | pir | | R5PM25 ribosomal protein PsCL25 precursor, chloroplast - garden pea
>gi|20877 | emb | CAA32187 | (X14022) PsCL25 ribosomal preprotein (AA -30 to 74) [Pisum sativum]
- % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 367: from 1 to 48
Maximum Length Sequence: related to: Clone IDs:
26930 Public Genomic DNA: gi No: 5225383 Predicted Exons: SINGLE 64539 . , 64276 GENBANK
INIT 64787 . , 64692 OCKHAMG- -CDS TERM 64620 . , 64276 OCKHAMG- -CDS gi No: 6136349 Predicted Exons: INIT 126797., 126892 OCKHAMG- -CDS TERM 126964., 127308 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 368
- Ceres seq_id 2025471
- Alternative transcription start site(s) located in SEQ ID NO 368: 95,96, 97, 98,100,101,102,105,106,110
- Clone 26930 starts at 97 and ends at 631 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 369 - Ceres seq_id 2025472
- Location of start within SEQ ID NO 368: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 242
- gi No. 5732082
- Description: (AF162444) contains similarity to Solanum lycopersicum (tomato) wound induced protein (GB:X59882) [Arabidopsis thaliana]
- % Identity: 100
- Alignment Length: 87
- Location of Alignment in SEQ ID NO 369: from 60 to 146
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 370
- Ceres seq_id 20254 , 3
- Location of start within SEQ ID NO 368: at 178 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 243 - gi No. 5732082
- Description: (AF162444) contains similarity to Solanum lycopersicum (tomato) wound induced protein (GB:X59882) [Arabidopsis thaliana]
- % Identity: 100 - Alignment Length: 87
- Location of Alignment in SEQ ID NO 370: from 1 to 87
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 371
- Ceres seq_id 2025474
- Location of start within SEQ ID NO 368: at 214 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 244
- gi No. 5732082
- Description: (AF162444) contains similarity to Solanum lycopersicum (tomato) wound induced protein (GB:X59882) [Arabidopsis thaliana]
- % Identity: 100
- Alignment Length: 87
- Location of Alignment in SEQ ID NO 371: from 1 to 75
Maximum Length Sequence related to:
Clone IDs:
27681
Public Genomic DNA: gi No: 6434227
Predictec Exons :
INTR 51354 . . 51417 OCKHAMG-CDNA
INTR 51529 . . 51786 OCKHAMG-CDNA
INIT 47952 . . 48020 OCKHAMG-CDS
INTR 48144 . . 48440 OCKHAMG-CDS
INTR 48542 . . 48757 OCKHAMG-CDS
INTR 489C8 . . 49027 OCKHAMG-CDS
INTR 49117 . . 49654 OCKHAMG-CDS
TERM 50075 . . 50184 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 372
- Ceres seq_id 2025475
- Alternative transcription start site(s) located in SEQ ID NO 372:
1242,1251,1270,1271,1275,1276,1280,1287,1288,1290,1292,1293,1 301,1302,1305,1307,1314,1318,1321,1325 1326,1330 - Clone 27681 starts at 1242 and ends at 2029 in cDNA. B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 373
- Ceres seq_id 2025476
- Location of start within SEQ ID NO 372: at 1 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide ( s ) (Dp) Related Amino Acid Sequences
- Alignment No. 245
- gi No. 2739366
- Description: (AC002505) SF16 like protein [Arabidopsis thaliana] - % Identity: 45
- Alignment Length: 373 - Location of Alignment in SEQ ID NO 373: from 61 to 418
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 374
- Ceres seq_id 2025477
- Location of start within SEQ ID NO 372: at 316 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 246
- gi No. 2739366
- Description: (AC002505) SF16 like protein [Arabidopsis thaliana]
- % Identity: 45
- Alignment Length: 373
- Location of Alignment in SEQ ID NO 374: from 1 to 313
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 375
- Ceres seq_id 2025478
- Location of start within SEQ ID NO 372: at 364 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 375: at 21 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 247
- gi No. 2739366
- Description: (AC002505) SF16 like protein [Arabidopsis thaliana] - % Identity: 45
- Alignment Length: 373
- Location of Alignment in SEQ ID NO 375: from 1 to 297
Maximum Length Sequence related to:
Clone IDs:
14564
Public Genomic DNA: gi No: 4415905
Predictec 1 Exons:
INTR 3235 . . 3181 OCKHAMG-CDNA
INTR 2694 . . 2619 OCKHAMG-CDNA
INTR 2509 . . 2408 OCKHAMG-CDNA
INTR 2319 . . 2171 OCKHAMG-CDNA
INTR 2076 . . 1784 OCKHAMG-CDNA INIT 3191 3181 OCKHAMG-CDS
INTR 2694 2619 OCKHAMG-CDS
INTR 2509 2408 OCKHAMG-CDS
INTR 2319 2171 OCKHAMG-CDS
TERM 2076 1920 OCKHAMG-CDS gi No: 4581138
Predicted Exons :
INTR 100911 100857 OCKHAMG-CDNA I INNTTRR 1 10000337700... 100295 OCKHAMG-CDNA
INTR 100185 100084 OCKHAMG-CDNA
INTR 99995 99847 OCKHAMG-CDNA
INTR 99752 99460 OCKHAMG-CDNA I INNIITT 1 10000886677... 100857 OCKHAMG-CDS
INTR 100370 100295 OCKHAMG-CDS
INTR 100185 100084 OCKHAMG-CDS
INTR 99995 99847 OCKHAMG-CDS
TERM 99752 99596 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 376
- Ceres seq_id 2025524
- Alternative transcription start site(s) located in SEQ ID NO 376: -35, -26, -25, -2, 2, 3, 4, 5, 6, 7, 8, 9, 15, 16, 17, 32
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 377
- Ceres seq_id 2025525 - Location of start within SEQ ID NO 376: at 47 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L24e
- Location within SEQ ID NO 377: from 3 to 73 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 248
- gi No. 6094040 - Description: 60S RIBOSOMAL PROTEIN L24
>gi I 2961300 | emb | CAA12358 I (AJ225027) ribosomal protein L24 [Cicer arietinum]
- % Identity: 88.3
- Alignment Length: 163 - Location of Alignment in SEQ ID NO 377: from 1 to
163
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 378
- Ceres seq_id 2025526
- Location of start within SEQ ID NO 376: at 212 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 249
- gi No. 6094040
- Description: 60S RIBOSOMAL PROTEIN L24 >gi|2961300 I emb | CAA12358 I (AJ225027) ribosomal protein L24 [Cicer arietinum]
- % Identity: 88.3
- Alignment Length: 163
- Location of Alignment in SEQ ID NO 378: from 1 to 108
Maximum Length Sequence : related to:
Clone IDs:
20767
Public Genomic DNA: gi No: 4519195
Predicted Exons:
INIT 50757 .. . 50625 OCKHAMG- -CDS
INTR 50001 .. . 49847 OCKHAMG- -CDS
INTR 49644 .. . 49561 OCKHAMG- -CDS
INTR 49391 .. . 49236 OCKHAMG- -CDS
INTR 49128 .. . 49023 OCKHAMG- -CDS
TERM 48810 .. . 48662 CCKHAMG- -CDS
(Ac) cDNA Polyrlucleotide Sequence
- Pat. Appln. SEQ ID NO 379
- Ceres seq_id 2025544
- Alternative transcription start site(s] located in SEQ ID NO 379:
656, 672, 680, 685, 701, 703, 706, 709, 713, 717, 728, 736, 741, 743
- Clone 20767 starts at 656 and ends at 1623 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 380
- Ceres seq_id 2025545
- Location of start within SEQ ID NO 379: at 599 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Domain of unknown function
- Location within SEQ ID NO 380: from 134 to 247 aa .
'Dp) Related Amino Acid Sequences
- Alignment No. 250
- gi No. 1708292 - Description: HEAT-RESPONSIVE PROTEIN 12
>gi I 1255116 (U50631) heat-responsive protein [Mus musculus]
- % Identity: 54.3
- Alignment Length: 129 - Location of Alignment in SEQ ID NO 380: from 119 to 247
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 381 - Ceres seq_id 2025546
- Location of start within SEQ ID NO 379: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 381: at 50 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s )
- Zinc finger, C3HC4 type (RING finger)
- Location within SEQ ID NO 381: from 171 to 211 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 251
- gi No. 2435518
- Description: (AF024504) contains similarity to C3HC4-type zinc fingers [Arabidopsis thaliana]
- % Identity: 31.4
- Alignment Length: 221
- Location of Alignment in SEQ ID NO 381: from 35 to 211
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 382
- Ceres seq_id 2025547
- Location of start within SEQ ID NO 379: at 16 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 382: at 45 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s ) - Zinc finger, C3HC4 type (RING finger)
- Location within SEQ ID NO 382: from 166 to 206 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 252
- gi No. 2435518
- Description: (AF024504) contains similarity to C3HC4-type zinc fingers [Arabidopsis thaliana]
- % Identity: 31.4 - Alignment Length: 221 - Location of Alignment in SEQ ID NO 382: from 30 to 206
Maximum Length Sequence: related to: Clone IDs: 7802 Public Genomic DNA: gi No: 441592C Predicted Exons : INTR 60672 ., 61210 OCKHAMG-CDNA
SINGLE 60712 ... 61119 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 383
- Ceres seq_id 2026207
- Alternative transcription start site(s) located in SEQ ID NO 383:
2,3,4,5
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 384
- Ceres seq_id 2026208
- Location of start within SEQ ID NO 383: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide s)
(Dp) Related Amino Ac d Sequences
- Alignment No. 253 - gi No. 4757974
- Description: ref I NP_004057.1 | pCETNl | centrin, EF- hand protein, 1 >gi | 2493440 I sp | Q12798 I CAT2_HUMAN CALTRACTIN, ISOFORM 2 (CENTRIN) >gi I 414993 (U03270) centrin [Homo sapiens] - % Identity: 34.3
- Alignment Length: 102
- Location of Alignment in SEQ ID NO 384: from 19 to 120
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 385
- Ceres seq_id 2026209
- Location of start within SEQ ID NO 383: at 41 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 254
- gi No. 4757974 - Description: ref | NP_004057.1 | pCETNl | centrin, EF- hand protein, 1 >gi I 2493440 | sp | Q12798 | CAT2_HUMAN CALTRACTIN, ISOFORM 2 (CENTRIN) >gi I 414993 (U03270) centrin [Homo sapiens]
% Identity: 34.3
Alignment Length: 102
Location of Alignment in SEQ ID NO 385: from 6 to
.07
IB) Polypeptide Sequence
- Pat. Λppln. SEQ ID NO 386
- Ceres seq_id 2026210
- Location of start within SEQ ID NO 383: at 62 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 255
- gi No. 4757974
- Description: ref I NP_004057.1 | pCETNl | centrin, EF- hand protein, 1 >gi | 2493440 I sp I Q12798 | CAT2_HUMAN CALTRACTIN, ISOFORM 2 (CENTRIN) >gi 1414993 (U03270) centrin Homo sapiens]
- % Identity: 34.3
- Alignment Length: 102
- Location of Alignment in SEQ ID NO 386: from 1 to 100
Maximum Length Sequence: Public Genomic DNA: gi No: 4038029 Predicted Exons: INIT 46188 ., 46125 GENBANK TERM 46021 ., 45852 GENBANK
INTR 46258 46125 OCKHAMG-CDNA INTR 46021 45663 OCKHAMG-CDNA
INIT 47157 47119 OCKHAMG-CDS INTR 46278 46125 OCKHAMG-CDS TERM 46021 45852 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 387
- Ceres seq id 2026982
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 388
- Ceres seq_id 2026983
- Location of start within SEQ ID NO 387: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 388: at 73 aa. (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Gamma-thionins family - Location within SEQ ID NO 388: from 74 to 120 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 256
- gi No. 1209258 - Description: (L31937) protease inhibitor II
[Brassica rapa]
- % Identity: 87
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 388: from 44 to 120
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 389
- Ceres seq_id 2026984 - Location of start within SEQ ID NO 387: at 34 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 389: at 54 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Gamma-thionins family
- Location within SEQ ID NO 389: from 63 to 109 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 257
- gi No. 1209258
- Description: (L31937) protease inhibitor II [Brassica rapa]
- % Identity: 87 - Alignment Length: 77
- Location of Alignment in SEQ ID NO 389: from 33 to 109
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 390
- Ceres seq_id 2026985
- Location of start within SEQ ID NO 387: at 130 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 390: at 22 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Gamma-thionins family
- Location within SEQ ID NO 390: from 31 to 77 aa ,
(Dp) Related Amino Acid Sequences - Alignment No. 258
- gi No. 1209258
- Description: (L31937) protease inhibitor II [Brassica rapa]
- % Identity: 87
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 390: from 1 to 77
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 391
- Ceres seq_id 2026986
- Location of start within SEQ ID NO 387: at 30 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s )
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: related to:
Clone IDs:
251127
Public Genomic DNA: gi No: 42206 40 Predicted Exons
INIT 67 833 68135 OCKHAMG-CDS
INTR 68 253 58366 OCKHAMG-CDS
INTR 68 457 68552 OCKHAMG-CDS
INTR 68 720 68794 OCKHAMG-CDS
INTR 68 898 68965 OCKHAMG-CDS
INTR 69 056 69066 OCKHAMG-CDS
INTR 69 422 69624 OCKHAMG-CDS
INTR 69 858 70202 OCKHAMG-CDS
INTR 70 315 70428 OCKHAMG-CDS
INTR 70 516 70611 OCKHAMG-CDS
INTR 70 923 70997 OCKHAMG-CDS
INTR 71 103 71173 OCKHAMG-CDS
TERM 71 737 71749 OCKHAMG-CDS
(Ac) cDNA Polynicleotide Sequence
- Pat. Appln. SEQ I D NO 392
- Ceres se id 2027300
- Alternative transcription start site(s) located in SEQ
ID NO 392:
38,53,55 , 63 ,82,84,85,103,160
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 393
- Ceres seq_id 2027301
- Location of start within SEQ ID NO 392 at 177 nt, (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 259 - gi No. 5020103
- Description: (AF148219) fibrillin [Nostoc PCC8009]
- % Identity: 30.3
- Alignment Length: 122 - Location of Alignment in SEQ ID NO 393: from 75 to 189
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 394 - Ceres seq_id 2027302
- Location of start within SEQ ID NO 392: at 213 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 260
- gi No. 5020103
- Description: (AF148219) fibrillin [Nostoc PCC8009] - % Identity: 30.3
- Alignment Length: 122
- Location of Alignment in SEQ ID NO 394: from 63 to 177 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 395
- Ceres seq_id 2027303
- Location of start within SEQ ID NO 392: at 252 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 261
- gi No. 5020103 - Description: (AF148219) fibrillin [Nostoc
PCC8009]
- % Identity: 30.3
- Alignment Length: 122
- Location of Alignment in SEQ ID NO 395: from 50 to 164
Maximum Length Sequence: related to: Clone IDs: 271260
Public Genomic DNA: gi No: 6056186
Predicted Exons:
INIT 66600 ... 66465 OCKHAMG-CDS
TERM 66390 ... 66083 OCKHAMG-CDS gi No: 6087919
Predicted Exons:
INIT 31657 ... 31522 OCKHAMG-CDS
TERM 31447 ... 31140 OCKHAMG-CDS gi No: 6119514
Predicted Exons:
INIT 32265 ... 32130 OCKHAMG-CDS
TERM 32055 ... 31748 OCKHAMG-CDS gi No: 6143857
Predicted Exons:
INIT 34633 ... 34768 OCKHAMG-CDS
TERM 34843 ... 35150 OCKHAMG-CDS gi No: 6175136
Predicted Exons:
INIT 34136 ... 34271 OCKHAMG-CDS
TERM 34346 ... 34653 OCKHAMG-CDS gi No: 6223634
Predicted Exons:
INIT 34137 ... 34272 OCKHAMG-CDS
TERM 34347 ... 34654 OCKHAMG-CDS
( Ac : cDNA Polynucleotide ! Sequence
- Pat. Appln. SEQ ID NO 396
- Ceres seq id 2027375
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 397
- Ceres seq_id 2027376
- Location of start within SEQ ID NO 396: at 2 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Bacterial mutT protein
- Location within SEQ ID NO 397: from 27 to 68 aa , (Dp) Related Amino Acid Sequences
- Alignment No. 262
- gi No. 2622420
- Description: (AE000895) mutator MutT protein [Methanobacterium thermoautotrophicum] - % Identity: 42.3
- Alignment Length: 98
- Location of Alignment in SEQ ID NO 397: from 13 to 109
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 398 - Ceres seq_id 2027377
- Location of start within SEQ ID NO 396: at 17 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Bacterial mutT protein
- Location within SEQ ID NO 398: from 22 to 63 aa
(Dp) Related Amino Acid Sequences - Alignment No. 263
- gi No. 2622420
- Description: (AE000895) mutator MutT protein [Methanobacterium thermoautotrophicum]
- % Identity: 42.3 - Alignment Length: 98
- Location of Alignment in SEQ ID NO 398: from to 104
'olypeptide Sequence
- Pat. Appln. SEQ ID NO 399
- Ceres seq_id 2027378
- Location of start within SEQ ID NO 396: at 1. nt,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 264
- gi No. 2622420
- Description: (AE000895) mutator MutT protein [Methanobacterium thermoautotrophicum]
- % Identity: 42.3
- Alignment Length: 98
- Location of Alignment in SEQ ID NO 399: from 1 to 47
Maximum Length Sequence: Public Genomic DNA: gi No: 5868932 Predicted Exons : INIT 99857 .. 96712 GENBANK INTR 96123 .. 95883 GENBANK TERM 95642 .. 95199 GENBANK
INTR 96097 .. . 95883 OCKHAMG- -CDNA INTR 95642 ... 95047 OCKHAMG--CDNA
INIT 96035 .. . 95883 OCKHAMG- -CDS TERM 95642 ... 95199 OCKHAMG--CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 400 - Ceres seq_id 2028729
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 401
- Ceres seq_id 2028730
- Location of start within SEQ ID NO 400: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- C2 domain
- Location within SEQ ID NO 401: from 671 to 762 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 265
- gi No. 3142295
- Description: (AC002411) Strong similarity to phosphoribosylanthranilate transferase gb|D86180 from Pisum sativum. [Arabidopsis thaliana]
- % Identity: 45.6
- Alignment Length: 865
- Location of Alignment in SEQ ID NO 401: from 211 to 1050
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 402
- Ceres seq_id 2028731
- Location of start within SEQ ID NO 400: at 199 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
- C2 domain
- Location within SEQ ID NO 402: from 605 to 696 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 266
- gi No. 3142295 - Description: (AC002411) Strong similarity to phosphoribosylanthranilate transferase gb|D86180 from Pisum sativum. [Arabidopsis thaliana]
- % Identity: 45.6
- Alignment Length: 865 - Location of Alignment in SEQ ID NO 402: from 145 to 984
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 403 - Ceres seq_id 2028732
- Location of start within SEQ ID NO 400: at 232 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- C2 domain - Location within SEQ ID NO 403: from 594 to 685 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 267 - gi No. 3142295
- Description: (AC002411) Strong similarity to phosphoribosylanthranilate transferase gb|D86180 from Pisum sativum. [Arabidopsis thaliana]
- % Identity: 45.6 - Alignment Length: 865
- Location of Alignment in SEQ ID NO 403: from 134 to 973
Maximum Length Sequence: related to: Clone IDs: 9214 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 404 - Ceres seq_id 2029079
- Alternative transcription start site(s) located in SEQ ID NO 404:
-4,-1,2,3,4,8,9,10,11,14,15,16,17,18,20,23,24 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 405
- Ceres seq_id 2029080
- Location of start within SEQ ID NO 404: at 3 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 268
- gi No. 132825 - Description: 50S RIBOSOMAL PROTEIN CL25,
CHLOROPLAST PRECURSOR >gi I 71308 I pir | | R5PM25 ribosomal protein
PsCL25 precursor, chloroplast - garden pea
>gi|20877 | emb | CAA32187 | (X14022) PsCL25 ribosomal preprotein
(AA -30 to 74) [Pisum sativum] - % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 405: from 14 to 95 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 406 - Ceres seq__id 2029081
- Location of start within SEQ ID NO 404: at 39 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 406: at 16 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 269
- gi No. 132825
- Description: 50S RIBOSOMAL PROTEIN CL25, CHLOROPLAST PRECURSOR >gi | 71308 | pir | | R5PM25 ribosomal protein PsCL25 precursor, chloroplast - garden pea
>gi 120877 | emb | CAA32187 | (X14022) PsCL25 ribosomal preprotein (7AA -30 to 74) [Pisum sativum]
- % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 406: from 2 to 83
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 407
- Ceres seq__id 2029082
- Location of start within SEQ ID NO 404 at 144 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 270
- gi No. 132825
- Description: 50S RIBOSOMAL PROTEIN CL25, CHLOROPLAST PRECURSOR >gi I 71308 | pir | | R5PM25 ribosomal protein PsCL25 precursor, chloroplast - garden pea
>gi|20877 | emb | CAA32187 | (X14022) PsCL25 ribosomal preprotein (AA -30 to 74) [Pisum sativum]
- % Identity: 56.1
- Alignment Length: 82
- Location of Alignment in SEQ ID NO 407: from 1 to 48
Maximum Length Sequence: Public Genomic DNA: gi No: 6434227
Predicted Exons:
INTR 50076 . . 50370 OCKHAMG- -CDNA
INTR 50793 . . 50874 OCKHAMG- -CDNA
INTR 51163 . . 51227 OCKHAMG- -CDNA
INTR 51331 . . 51417 OCKHAMG- -CDNA
INTR 51529 . . 51786 OCKHAMG- -CDNA
INIT 50200 . . 50370 OCKHAMG- -CDS INTR 50793 ... 50874 OCKHA G--CDS
INTR 51163 .. . 51227 OCKHAMG- -CDS
INTR 51331 .. . 51417 OCKHAMG- -CDS
TERM 51529 .. . 51630 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 408
- Ceres seq_id 2029225
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 409
- Ceres seq_id 2029226
- Location of start within SEQ ID NO 408: at 125 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 271
- gi No. 1352051
- Description: ATP SYNTHASE D CHAIN, MITOCHONDRIAL >gi I 484646|pir I I JS0739 H+-transporting ATP synthase (EC 3.6.1.34) chain d precursor - rat >gi | 286204 | dbj I BAA02422 | (D13120) ATP synthase subunit d precursor [Rattus norvegicus;
- % Identity: 28.6
- Alignment Length: 145
- Location of Alignment in SEQ ID NO 409: from 15 to 154
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 410
- Ceres seq_id 2029227
- Location of start within SEQ ID NO 408: at 194 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 272
- gi No. 1352051 - Description: ATP SYNTHASE D CHAIN, MITOCHONDRIAL
>gi| 484646|pir I I JS0739 H+-transporting ATP synthase (EC 3.6.1.34) chain d precursor - rat >gi I 286204 I dbj | BAA02422 | (D13120) ATP synthase subunit d precursor [Rattus norvegicus]
- % Identity: 28.6 - Alignment Length: 145
- Location of Alignment in SEQ ID NO 410: from 1 to 131
Maximum Length Sequence: Public Genomic DNA: gi No: 6056185 Predicted Exons :
INTR 21555 22692 OCKHAMG- -CDNA
INTR 22891 23339 OCKHAMG--CDNA
INTR 22502 22692 OCKHAMG- -CDNA
INTR 22891 23338 OCKHAMG--CDNA
INIT 21706 22692 OCKHAMG- -CDS TERM 22891 23124 OCKHAMG--CDS gi No: 6091703 Predicted Exons INTR 21555 22692 OCKHAMG- -CDNA INTR 22891 23339 OCKHAMG--CDNA
INTR 22502 22692 OCKHAMG- -CDNA INTR 22891 23338 OCKHAMG--CDNA
INIT 21706 22692 OCKHAMG- -CDS TERM 22891 23124 OCKHAMG--CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 411
- Ceres seq_id 2029422
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 412
- Ceres seq_id 2029423
- Location of start within SEQ ID NO 411: at 152 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- CONSTANS family zinc finger
- Location within SEQ ID NO 412: from 17 to 57 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 273
- gi No. 1076301
- Description: CONSTANS protein - Arabidopsis thaliana >gi | 1161514 | emb | CAA64407 | (X94937) CONSTANS protein [Arabidopsis thaliana]
- % Identity: 49.2
- Alignment Length: 63
- Location of Alignment in SEQ ID NO 412: from 12 to 74
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 413
- Ceres seq_id 2029424
- Location of start within SEQ ID NO 411: at 155 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- CONSTANS family zinc finger
- Location within SEQ ID NO 413: from 16 to 56 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 274
- gi No. 1076301
- Description: CONSTANS protein Arabidopsis thaliana >gi|1161514 | emb | CAA64407 | (X94937 CONSTANS protein
[Arabidopsis thaliana]
- % Identity: 49.2
- Alignment Length: 63
- Location of Alignment in SEQ ID NO 413: from 11 to 73
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 414
- Ceres seq_id 2029425
- Location of start within SEQ ID NO 411: at 443 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 275
- gi No. 1076301
- Description: CONSTANS protein - Arabidopsis thaliana >gi I 1161514 | emb I CAA64407 | (X94937) CONSTANS protein
[Arabidopsis thaliana] - % Identity: 69.8
- Alignment Length: 43
- Location of Alignment in SEQ ID NO 414: from 260 to 302
Maximum Length Sequence: Public Genomic DNA: gi No: 5832738 Predicted Exons:
INTR 56241 . . 56150 OCKHAMG- -CDNA
INTR 56041 . . 55864 OCKHAMG- -CDNA
INTR 55493 . . 55317 OCKHAMG- -CDNA
INTR 55216 . . 55085 OCKHAMG- -CDNA
INTR 54898 . . 54803 OCKHAMG- -CDNA
INTR 54725 . . 54609 OCKHAMG- -CDNA
INTR 54510 . . 54415 OCKHAMG- -CDNA
INTR 54288 . . 54176 OCKHAMG- -CDNA
INTR 54077 . . 53779 OCKHAMG- -CDNA
INIT 56181 . . 56150 OCKHAMG- -CDS
INTR 56041 . . 55864 OCKHAMG- -CDS
INTR 55493 . . 55317 OCKHAMG- -CDS INTR 55216 55085 OCKHAMG-CDS
INTR 54898 54803 OCKHAMG-CDS
INTR 54725 54609 OCKHAMG-CDS
INTR 54510 54415 OCKHAMG-CDS
INTR 54288 54176 OCKHAMG-CDS
TERM 54077 53954 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 415
- Ceres seq id 2029806
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 416
- Ceres seq_id 2029807
- Location of start within SEQ ID NO 415: at 1 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Aminotransferase class IV
- Location within SEQ ID NO 416: from 68 to 352 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 276 - gi No. 3540183
- Description: (AC004122) Highly Similar to branched-chain amino acid aminotransferase [Arabidopsis thaliana]
- % Identity: 53.8 - Alignment Length: 318
- Location of Alignment in SEQ ID NO 416: from 55 to 371
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 417
- Ceres seq_id 2029808
- Location of start within SEQ ID NO 415: at 61 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Aminotransferase class IV
- Location within SEQ ID NO 417: from 48 to 332 aa,
(Dp) Related Amino Acid Sequences - Alignment No. 277
- gi No. 3540183
- Description: (AC004122) Highly Similar to branched-chain amino acid aminotransferase [Arabidopsis thaliana] - % Identity: 53.8
- Alignment Length: 318 Location of Alignment in SEQ ID NO 417: from 35 to 351
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 418
- Ceres seq_id 2029809
- Location of start within SEQ ID NO 415: at 163 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Aminotransferase class IV
- Location within SEQ ID NO 418: from 14 to 298 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 278
- gi No. 3540183
- Description: (AC004122) Highly Similar to branched-chain amino acid aminotransferase [Arabidopsis thaliana] - % Identity: 53.8
- Alignment Length: 318
- Location of Alignment in SEQ ID NO 418: from 1 to 317
Maximum Length Sequence Public Genomic DNA: gi No: 5822667 Predicted Exons: INTR 59013 . 59999 OCKHAMG-CDNA
SINGLE 59071 . 59769 OCKHAMG-CDS gi No: 6041831 Predicted Exons:
INTR 53943 . 54929 OCKHAMG-CDNA
SINGLE 54001 . 54699 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 419
- Ceres seq id 2030038
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 420
- Ceres seq_id 2030039
- Location of start within SEQ ID NO 419: at 2 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 279 gi No. 4009495 Description: (AF068904) YlmG [Staphylococcus aureus]
% Identity: 31.7
Alignment Length: 63
Location of Alignment in SEQ ID NO 420: from 177 to 239
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 421
- Ceres seq_id 2030040
- Location of start within SEQ ID NO 419: at 59 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 421: at 19 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 280 - gi No. 4009495
- Description: (AF068904) YlmG [Staphylococcus aureus]
- % Identity: 31.7
- Alignment Length: 63 - Location of Alignment in SEQ ID NO 421: from 158 to 220
Maximum Length Sequence: Public Genomic DNA: gi No: 4539290 Predicted Exons:
INIT 6134 . . 6132 GENBANK
INTR 6021 . . 5973 GENBANK
INTR 5588 . . 5309 GENBANK
INTR 5226 . . 5106 GENBANK
TERM 4951 . . 4871 GENBANK
INTR 6208 . . 6132 OCKHAMG- -CDNA
INTR 6021 . . 5973 OCKHAMG- -CDNA
INTR 5588 . . 5309 OCKHAMG- -CDNA
INTR 5226 . . 5106 OCKHAMG- -CDNA
INTR 4951 . . 4724 OCKHAMG- -CDNA
INIT 6134 . . 6132 OCKHAMG- -CDS
INTR 6021 . . 5973 OCKHAMG- -CDS
INTR 5588 . . 5309 OCKHAMG- -CDS
INTR 5226 . .. 5106 OCKHAMG- -CDS
TERM 4951 . . 4871 OCKHAMG- -CDS gi No: 4914454 Predicted Exons: INTR 39557 39481 OCKHAMG-CDNA INTR 39370 ... 39322 OCKHAMG--CDNA
INTR 38937 .. . 38658 OCKHAMG- -CDNA
INTR 38575 .. . 38455 OCKHAMG- -CDNA
INTR 38300 .. . 38073 OCKHAMG- -CDNA
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 422
- Ceres seq id 2031778
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 423
- Ceres seq__id 2031779
- Location of start within SEQ ID NO 422: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 281 - gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 53.1
- Alignment Length: 164 - Location of Alignment in SEQ ID NO 423: from 25 to 186
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 424
- Ceres seq_id 2031780
- Location of start within SEQ ID NO 422: at 75 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 282
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus] - % Identity: 53.1
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 424: from 1 to 162
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 425
- Ceres seq_id 2031781
- Location of start within SEQ ID NO 422: at 210 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 283
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 53.1
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 425: from 1 to 117
Maximum Length Sequence: Public Genomic DNA: gi No: 6434226 Predicted Exons:
INTR 17873 .. . 17514 OCKHAMG-CDNA
INTR 17046 .. . 16869 OCKHAMG-CDNA
INIT 17854 .. . 17514 OCKHAMG-CDS
TERM 17046 .. . 17028 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 426
- Ceres seq id 2032723
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 427
- Ceres seq_id 2032724
- Location of start within SEQ ID NO 426: at 20 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 427: at 24 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 427: from 28 to 115 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 284 - gi No. 899224
- Description: (X60318) E2 [Brassica napus] >gi I 384340 |prf I I 1905428A phospholipid transfer protein [Brassica napus]
- % Identity: 79 - Alignment Length: 119
- Location of Alignment in SEQ ID NO 427: from 1 to 119
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 428
- Ceres seq id 2032725 - Location of start within SEQ ID NO 426: at 71 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Plant lipid transfer protein family
- Location within SEQ ID NO 428: from 11 to 98 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 285 - gi No. 899224
- Description: (X60318) E2 [Brassica napus] >gi I 38434C Iprf I I 1905428A phospholipid transfer protein [Brassica napus]
- % Identity: 79 - Alignment Length: 119
- Location of Alignment in SEQ ID NO 428: from 1 to 102
|B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 429
- Ceres seq_id 2032726
- Location of start within SEQ ID NO 426: at 1 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: Public Genomic DNA: gi No: 6143856
Predicted Exons: INIT 30571 .. 30464 OCKHAMG- -CDS TERM 30327 .. 30238 OCKHAMG--CDS gi No: 6223633 Predicted Exons:
INIT 30571 .. 30464 OCKHAMG- -CDS TERM 30327 .. 30238 OCKHAMG--CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 430 - Ceres seq id 2035536
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 431
- Ceres seq_id 2035537
- Location of start within SEQ ID NO 430: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 431: at 20 aa. - (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 286
- gi No. 3024192
- Description: NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT (COMPLEX I-MWFE) (CI-MWFE) >gi I 2275037 | emb | CAA68977 | (Y07708) NADH dehydrogenase [Mus musculus]
- % Identity: 31.5
- Alignment Length: 54
- Location of Alignment in SEQ ID NO 431: from 4 to 56
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 432
- Ceres seq_id 2035538
- Location of start within SEQ ID NO 430: at 2 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 433 - Ceres seq_id 2035539
- Location of start within SEQ ID NO 430: at 25 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 433: at 17 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 287
- gi No. 3024192 - Description: NADH-UBIQUINONE OXIDOREDUCTASE MWFE
SUBUNIT (COMPLEX I-MWFE) (CI-MWFE) >gi | 2275037 | emb | CAA68977 | (Y07708) NADH dehydrogenase [Mus musculus]
- % Identity: 31.5
- Alignment Length: 54 - Location of Alignment in SEQ ID NO 433: from 1 to
48
Maximum Length Sequence: Public Genomic DNA: gi No: 6136357 Predicted Exons:
INIT 51922 . . 51830 OCKHAMG- -CDS
INTR 51129 . . 51055 OCKHAMG- -CDS
INTR 50958 . . 50806 OCKHAMG- -CDS
INTR 50706 . . 50608 OCKHAMG- -CDS
TERM 50326 . . 50243 OCKHAMG- -CDS gi No: 6143858
Predicted Exons :
INIT 51922 . . 51830 OCKHAMG- -CDS
INTR 51129 . . 51055 OCKHAMG- -CDS
INTR 50958 . . 50806 OCKHAMG- -CDS
INTR 50706 . . 50608 OCKHAMG- -CDS
TERM 50326 . . 50243 OCKHAMG- -CDS gi No: 6449510
Predicted Exons :
INTR 9035 . . 9111 OCKHAMG- -CDNA
INTR 9208 . . 9360 OCKHAMG- -CDNA
INTR 9460 . . 9558 OCKHAMG- -CDNA
INTR 9840 . . 9992 OCKHAMG- -CDNA (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 434
- Ceres seq_id 2035575
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 435
- Ceres seq_id 2035576
- Location of start within SEQ ID NO 434 at 1 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 288
- gi No. 6066609 - Description: AJ009987) chloroplast channel forming outer membrane protein [Pisum sativum]
- % Identity: 54.2
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 435: from 1 to 167
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 436
- Ceres seq_id 2035577
- Location of start within SEQ ID NO 434: at 13 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 289
- gi No. 6066609
- Description: (AJ009987) chloroplast channel forming outer membrane protein [Pisum sativum]
- % Identity: 54.2 - Alignment Length: 177 Location of Alignment in SEQ ID NO 436: from 1 to
163
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 437
- Ceres seq_id 2035578
- Location of start within SEQ ID NO 434 at 40 nt,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 290
- gi No. 6066609
- Description: (AJ009987) chloroplast channel forming outer membrane protein [Pisum sativum]
- % Identity: 54.2
- Alignment Length: 177
- Location of Alignment in SEQ ID NO 437: from to 154
Maximum Length Sequence: Public Genomic DNA: gi No: 6434213
Predicted Exons:
INIT 54056 . . 54085 OCKHAMG- -CDS
INTR 54178 . . 54325 OCKHAMG- -CDS
INTR 54401 . . 54572 OCKHAMG- -CDS
INTR 54807 . . 54993 OCKHAMG- -CDS
TERM 55079 . . 55291 OCKHAMG- -CDS
(Ac; cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 438
- Ceres seq_id 2036457
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 439
- Ceres seq_id 2036458
- Location of start within SEQ ID NO 43. at 1 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 439: from 104 to IE aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 291
- gi No. 133940
- Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 708511 pir I I R3XL3A ribosomal protein S3a - African clawed frog >gi| 65091 | emb | CAA40592 (X57322; ribosomal protein Sla [Xenopus laevis]
- % Identity: 75.1
- Alignment Length: 250
- Location of Alignment in SEQ ID NO 439: from 1 to 249
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 440
- Ceres seq_id 2036459
- Location of start within SEQ ID NO 438: at 130 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 440: from 61 to 145 aa
(Dp) Related Amino Acid Sequences
- Alignment No. 292
- gi No. 133940
- Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 70851 I pir M R3XL3A ribosomal protein S3a - African clawed frog >gi | 65091 | emb | CAA40592 | (X57322) ribosomal protein Sla [Xenopus laevis]
- % Identity: 75.1
- Alignment Length: 250
- Location of Alignment in SEQ ID NO 440: from 1 to 206
Maximum Length Sequence: Public Genomic DNA: gi No: 6434218 Predicted Exons:
INIT 85292 . . 85282 OCKHAMG- -CDS
INTR 84903 . . 84828 OCKHAMG- -CDS
INTR 84730 . . 84629 OCKHAMG- -CDS
INTR 84524 . . 84376 OCKHAMG- -CDS
INTR 84282 . . 84156 OCKHAMG- -CDS
TERM 84148 . . 84065 OCKHAMG- -CDS
(Ac; cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 441
- Ceres seq id 2036585
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 442
- Ceres seq_id 2036586
- Location of start within SEQ ID NO 441: at 1 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L24e
- Location within SEQ ID NO 442: from 3 to 73 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 293
- gi No. 6094040
- Description: 60S RIBOSOMAL PROTEIN L24 >gi I 2961300 | emb | CAA12358 | (AJ225027) ribosomal protein L24 [Cicer arietinum]
- % Identity: 86.6
- Alignment Length: 158
- Location of Alignment in SEQ ID NO 442: from 1 to 156
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 443
- Ceres seq_id 2036587 - Location of start within SEQ ID NO 441: at 166 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 294
- gi No. 6094040
- Description: 60S RIBOSOMAL PROTEIN L24
>gi 12961300 | emb | CAA12358 | (AJ225027) ribosomal protein L24 [Cicer arietinum] - % Identity: 86.6
- Alignment Length: 158
- Location of Alignment in SEQ ID NO 443: from 1 to 101 Maximum Length Sequence: Public Genomic DNA: gi No: 5668776 Predicted Exons :
INIT 19552 ... 19704 OCKHAMG-CDS TERM 19947 ... 20279 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 444
- Ceres seq_id 2039554
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 445
- Ceres seq_id 2039555 - Location of start within SEQ ID NO 444: at 1 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 295
- gi No. 5882720
- Description: (AC008263) Similar to gb|D86180 phosphoribosylanthranilate transferase from Pisum sativum and contains 2 PF 100168 C2 (phospholipid binding) domains. ESTs gb|H76726, gb|T45544 and gb|N96377 come from this gene. [Arab...
- % Identity: 99.3
- Alignment Length: 151
- Location of Alignment in SEQ ID NO 445: from 1 to 151
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 446
- Ceres seq_id 2039556
- Location of start within SEQ ID NO 444: at 136 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 296
- gi No. 5882720
- Description: (AC008263) Similar to gb|D86180 phosphoribosylanthranilate transferase from Pisum sativum and contains 2 PF' 00168 C2 (phospholipid binding) domains. ESTs gb|H76726, gb|T45544 and gb|N96377 come from this gene. [Arab...
- % Identity: 99.3
- Alignment Length: 151
- Location of Alignment in SEQ ID NO 446: from 1 to 106
Maximum Length Sequence: Public Genomic DNA: gi No: 4263586
Predicted Exons:
INIT 44660 . . 44729 OCKHAMG- -CDS
INTR 44822 . . 44985 OCKHAMG- -CDS
INTR 45066 . . 45099 OCKHAMG- -CDS
INTR 45171 . . 45264 OCKHAMG- -CDS
TERM 45352 . . 45367 OCKHAMG- -CDS
(Ac; cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 447
- Ceres seq_id 2044283
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 448
- Ceres seq_id 2044284
- Location of start within SEQ ID NO 447: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 448: at 19 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 297
- gi No. 4512613
- Description: (AC004793) F28K20.12 [Arabidopsis thaliana]
- % Identity: 99.2 - Alignment Length: 122
- Location of Alignment in SEQ ID NO 448: from 1 to 122
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 449
- Ceres seq_id 2044285
- Location of start within SEQ ID NO 447: at 13 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 298
- gi No. 4512613
- Description: (AC004793) F28K20.12 [Arabidopsis thaliana]
- % Identity: 99.2
- Alignment Length: 122
- Location of Alignment in SEQ ID NO 449: from 1 to 118
.) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 450
- Ceres seq_id 2044286
- Location of start within SEQ ID NO 447 at 16 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 299 - gi No. 4512613
- Description: (AC004793) F28K20.12 [Arabidopsis thaliana]
- % Identity: 99.2
- Alignment Length: 122 - Location of Alignment in SEQ ID NO 450: from 1 to
117 Maximum Length Sequence : related to:
Clone IDs:
157859
Public Genomic DNA: gi No: 4519187
Predictec Exons :
INIT 64212 .. . 64316 OCKHAMG-CDS
INTR 64435 .. . 64599 OCKHAMG-CDS
INTR 64655 .. . 64789 OCKHAMG-CDS
INTR 64869 .. . 64952 OCKHAMG-CDS
INTR 65028 .. . 65143 OCKHAMG-CDS
INTR 65245 .. . 65346 OCKHAMG-CDS
INTR 65417 .. . 65530 OCKHAMG-CDS
INTR 65621 .. . 65677 OCKHAMG-CDS
INTR 65790 .. . 65856 OCKHAMG-CDS
INTR 65929 .. . 65982 OCKHAMG-CDS
INTR 66089 .. . 66163 OCKHAMG-CDS
INTR 66558 .. . 66593 OCKHAMG-CDS
INTR 66699 .. . 66811 OCKHAMG-CDS
TERM 68086 .. . 68098 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 451
- Ceres seq_id 2048114
- Alternative transcription start site(s) located in SEQ ID NO 451:
456
- Clone 157859 starts at 456 and ends at in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 452
- Ceres seq_id 2048115
- Location of start within SEQ ID NO 451: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 452: at 34 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 300
- gi No. 4850384
- Description: (AC007357) F3F19.3 [Arabidopsis thaliana] - % Identity: 66.2
- Alignment Length: 201
- Location of Alignment in SEQ ID NO 452: from 95 to 295
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 453 - Ceres seq_id 2048116
- Location of start within SEQ ID NO 451: at 19 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 453: at 28 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 301 - gi No. 4850384
- Description: (AC007357) F3F19.3 [Arabidopsis thaliana]
- % Identity: 66.2
- Alignment Length: 201 - Location of Alignment in SEQ ID NO 453: from 89 to 289
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 454 - Ceres seq_id 2048117
- Location of start within SEQ ID NO 451: at 22 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 454: at 27 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 302
- gi No. 4850384 - Description: (AC007357) F3F19.3 [Arabidopsis thaliana]
- % Identity: 66.2
- Alignment Length: 201
- Location of Alignment in SEQ ID NO 454: from 88 to 288
Maximum Length Sequence: Public Genomic DNA: gi No: 4519194 Predicted Exons:
INTR 15272 .. . 15482 OCKHAMG- -CDNA
INTR 15570 .. . 15615 OCKHAMG- -CDNA
INTR 16443 .. . 16834 OCKHAMG- -CDNA
INIT 15350 .. . 15482 OCKHAMG- -CDS
INTR 15570 .. . 15615 OCKHAMG- -CDS
TERM 16443 .. . 16671 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 455 - Ceres seq_id 2048271 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 456 - Ceres seq_id 2048272
- Location of start within SEQ ID NO 455: at 79 nt .
(C) Nomination and Annotation of Domains within Predicted Polypepti a (s) - Ribosomal protein S16
- Location within SEQ ID NO 456: from 9 to 70 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 303 - gi No. 3861401
- Description: (AJ235273) 30S RIBOSOMAL PROTEIN S16 (rpsP) [Rickettsia prowazekii]
- % Identity: 43.7
- Alignment Length: 103 - Location of Alignment in SEQ ID NO 456: from 1 to
102
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 457 - Ceres seq_id 2048273
- Location of start within SEQ ID NO 455: at 139 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Ribosomal protein S16
- Location within SEQ ID NO 457: from 1 to 50 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 304 - gi No. 3861401
- Description: (AJ235273) 30S RIBOSOMAL PROTEIN S16 (rpsP) [Rickettsia prowazekii]
- % Identity: 43.7
- Alignment Length: 103 - Location of Alignment in SEQ ID NO 457: from 1 to
82
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 458 - Ceres seq_id 2048274
- Location of start within SEQ ID NO 455: at 232 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 305 - gi No. 3861401
- Description: (AJ235273) 30S RIBOSOMAL PROTEIN S16 rpsP; [Rickettsia prowazekii]
- % Identity: 43.7
- Alignment Length: 103
- Location of Alignment in SEQ ID NO 458: from 1 to
51
Maximum Length Sequence
Public Genomic DNA: gi No: 4519195
Predicted Exons :
INIT 48116 . . 48096 OCKHAMG-CDS
INTR 48033 . . 47989 OCKHAMG-CDS
INTR 47604 . . 47531 OCKHAMG-CDS
INTR 47435 . . 47386 OCKHAMG-CDS
TERM 47286 . . 47192 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 459 - Ceres seq id 2048331
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 460
- Ceres seq_id 2048332
- Location of start -..ithin SEQ ID NO 459: at 1 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Domain of unknown function
- Location within SEQ ID NO 460: from 8 to 92 aa,
(Dp) Related Amino Acid Sequences - Alignment No. 306
- gi No. 5032215
- Description: ref | NP_005827.1 | pUK114 translational inhibitor protein pl4.5 >gi| 1717975 I sp| P52758 |UK14_HUMAN 14.5 KD TRANSLATIONAL INHIBITOR PROTEIN (P14.5) (UK114 ANTIGEN HOMOLOG) >gi| 1177435 I emb I CAA64670 I sapiens]
- % Identity: 58.8
- Alignment Length: 85
- Location of Alignment in SEQ ID NO 460: from 8 to 92
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 461
- Ceres seq_id 2048333
- Location of start within SEQ ID NO 459: at 79 nt (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Domain of unknown function
- Location within SEQ ID NO 461: from 1 to 66 aa,
(Dp) Related Amino Acid Sequences
- Alignment No. 307
- gi No. 5032215
- Description: ref I NP_005827.1 | pUK114 | translational inhibitor protein pl4.5
>gi|i 717975 I sp| P52758 |UK14_HUMAN 14.5 KD TRANSLATIONAL
INHIBITOR PROTEIN (P14.5) (UK114 ANTIGEN HOMOLOG) >σi| 1177435|emb|CAA64670 I sapiens]
- % Identity: 58.8
- Alignment Length: 85
- Location of Alignment in SEQ ID NO 461: from 1 to
66
;3) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 462
- Ceres seq_id 2048334
- Location of start within SEQ ID NO 459 at 139 nt,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 308
- gi No. 5032215
- Description: ref I NP_005827.1 | pUK114 | translational inhibitor protein pl4.5
>gi| 1717975 I sp| P52758 |UK14_HUMAN 14.5 KD TRANSLATIONAL INHIBITOR PROTEIN (P14.5) (UK114 ANTIGEN HOMOLOG) >gi| 1177435 I emb I CAA64670 I sapiens]
- % Identity: 58.8 - Alignment Length: 85
- Location of Alignment in SEQ ID NO 462: from 1 to 46
Maximum Length Sequence: Public Genomic DNA: gi No: 4589412 Predicted Exons:
INIT 37105 . . 37091 OCKHAMG- -CDS
INTR 36413 . . 36339 OCKHAMG- -CDS
INTR 36224 . . 36176 OCKHAMG- -CDS
INTR 35977 . . 35698 OCKHAMG- -CDS
INTR 35603 . . 35471 OCKHAMG- -CDS
TERM 35193 . . 35119 OCKHAMG- -CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 463 - Ceres seq_id 2048466
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 464
- Ceres seq_id 2048467
- Location of start within SEQ ID NO 463: at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 309
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 50.6
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 464: from 30 to 193
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 465
- Ceres seq_id 2048468
- Location of start within SEQ ID NO 463: at 4 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 310 - gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 50.6
- Alignment Length: 164 - Location of Alignment in SEQ ID NO 465: from 29 to 192
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 466 - Ceres seq_id 2048469
- Location of start within SEQ ID NO 463: at 88 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 311
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus] - % Identity: 50.6
- Alignment Length: 164 - Location of Alignment in SEQ ID NO 466: from 1 to
164
Maximum Length Sequence: Public Genomic DNA: gi No: 4914400 Predicted Exons: INTR 97410 ., 97833 OCKHAMG-CDNA
SINGLE 97525 97797 OCKHAMG-CDS gi No: 4938473
Predicted Exons
SINGLE 9769 10041 GENBANK
INTR 9654 10078 OCKHAMG-CDNA
INTR 10721 10880 OCKHAMG-CDNA
SINGLE 9769 10041 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 467
- Ceres seq_id 2050485
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 468
- Ceres seq_id 2050486
- Location of start within SEQ ID NO 467: at 2 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 312
- gi No. 2493089 - Description: ATP SYNTHASE F CHAIN, MITOCHONDRIAL
- % Identity: 29.7
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 468: from 52 to 125
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 469
- Ceres seq_id 2050487
- Location of start within SEQ ID NO 467: at 116 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
(Dp) Related Amino Acid Sequences
- Alignment No. 313 - gi No. 2493089
- Description: ATP SYNTHASE F CHAIN, MITOCHONDRIAL - % Identity: 29.7
- Alignment Length: 77
- Location of Alignment in SEQ ID NO 469: from 14 to 87
Maximum Length Sequence: Public Genomic DNA: gi No: 4454022 Predicted Exons:
INIT 55210 .. 55024 GENBANK
TERM 54477 .. 54209 GENBANK
INTR 55270 .. 55024 OCKHAMG- -CDNA
INTR 54477 .. 54299 OCKHAMG- -CDNA
INIT 55210 .. 55024 OCKHAMG- -CDS
TERM 54477 .. 54209 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 470 - Ceres seq_id 2050708
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 471
- Ceres seq__id 2050709
- Location of start within SEQ ID NO 470: at 61 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 314
- gi No. 2129641
- Description: major latex protein type 1 - Arabidopsis thaliana >gi I 1107493 I emb I CAA63026 | (X91960; ma or latex protein typel [Arabidopsis thaliana]
- % Identity: 71.3
- Alignment Length: 150
- Location of Alignment in SEQ ID NO 471: from 1 to 150
Maximum Length Sequence: Public Genomic DNA: gi No: 4914454 Predicted Exons:
INTR 42446 . . 41456 OCKHAMG-CDS
INTR 40358 . . 40280 OCKHAMG-CDS
INTR 39551 . . 39481 OCKHAMG-CDS
INTR 39415 . . 39322 OCKHAMG-CDS
INTR 39280 . . 39268 OCKHAMG-CDS
INTR 38937 . . 38658 OCKHAMG-CDS INTR 38575 ... 38455 OCKHAMG-CDS
TERM 38300 .. . 38220 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 472
- Ceres seq id 2050901
IB) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 473
- Ceres seq_id 2050902
- Location of start within SEQ ID NO 472: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 315
- gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 53.1
- Alignment Length: 147
- Location of Alignment in SEQ ID NO 473: from 416 to 560
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 474
- Ceres seq_id 2050903
- Location of start within SEQ ID NO 472: at 123 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s )
(Dp) Related Amino Acid Sequences
- Alignment No. 316 - gi No. 3688432
- Description: (AJ011705) 40S ribosomal protein S10 [Lumbricus rubellus]
- % Identity: 53.1
- Alignment Length: 147 - Location of Alignment in SEQ ID NO 474: from 376 to 520
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 475 - Ceres seq_id 2050904
- Location of start within SEQ ID NO 472: at 678 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 475: at 39 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide ( s ) (Dp) Related Amino Acid Sequences
- Alignment No. 317
- gi No. 3688432
- Descriptions (AJ011705) 40S ribosomal protein SIO [Lumbricus rubellus]
- % Identity: 53.1
- Alignment Length: 147
- Location of Alignment in SEQ ID NO 475: from 191 to 335
Maximum Length Sequence: Public Genomic DNA: gi No: 4725940
Predicted Exons:
SINGLE 96089 ... 95736 GENBANK
INTR 96156 ... 95622 OCKHAMG-CDNA
SINGLE 96083 95736 OCKHAMG-CDS gi No: 5823567 Predicted Exons:
SINGLE 96089 95736 GENBANK
INTR 96156 . 95622 OCKHAMG-CDNA
SINGLE 96083 95736 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 476
- Ceres seq id 2051325
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 477 - Ceres seq_id 2051326
- Location of start within SEQ ID NO 476: at 68 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 477: at 30 aa. (C) Nomination and Annotation of Domains within
Predicted Polypeptide ( s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 477: from 34 to 115 aa, (Dp) Related Amino Acid Sequences
- Alignment No. 318
- gi No. 4725952
- Description: (AL049730) AIRlA-like protein [Arabidopsis thaliana] - % Identity: 100
- Alignment Length: 117 - Location of Alignment in SEQ ID NO 477: from 1 to
117
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 478
- Ceres seq_id 2051327
- Location of start within SEQ ID NO 476: at 74 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 478: at 28 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Plant lipid transfer protein family
- Location within SEQ ID NO 478: from 32 to 113 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 319
- gi No. 4725952
- Description: (AL049730) AIRlA-like protein [Arabidopsis thaliana]
- % Identity: 100
- Alignment Length: 117
- Location of Alignment in SEQ ID NO 478: from 1 to 115
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 479
- Ceres seq_id 2051328
- Location of start within SEQ ID NO 476: at 288 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 479: at 61 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
Maximum Length Sequence: Public Genomic DNA: gi No: 4490717 Predicted Exons: INIT 87492 7378 GENBANK INTR 87034 6928 GENBANK INTR 86683 6641 GENBANK TERM 86445 6402 GENBANK
INTR 87555 7378 OCKHAMG- -CDNA INTR 87034 6928 OCKHAMG- -CDNA INTR 86683 6641 OCKHAMG- -CDNA INTR 86445 6257 OCKHAMG- -CDNA
INIT 87492 87378 OCKHAMG-CDS INTR 87034 ... 86928 OCKHAMG--CDS
INTR 86683 .. . 86641 OCKHAMG- -CDS
TERM 86445 .. . 86402 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 480
- Ceres seq id 2051633
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 481
- Ceres seq_id 2051634
- Location of start within SEQ ID NO 480 at 1 nt (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s )
(Dp) Related Amino Acid Sequences
- Alignment No. 320
- gi No. 1083282 - Description: cytochrome-c oxidase (EC 1.9.3.1) - mouse >gi 1567766 (L06465) cytochrome c oxidase [Mus musculus] >gi| 1094404 |prf I I2106151A cytochrome c oxidase : SUBUNIT=VIa [Mus musculus]
- % Identity: 41.4 - Alignment Length: 106
- Location of Alignment in SEQ ID NO 481: from 22 to 120
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 482
- Ceres seq_id 2051635
SEQ ID NO 480: at 64 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 321
- gi No. 1083282
- Description: cytochrome-c oxidase (EC 1.9.3.1) - mouse >gi 1567766 (L06465) cytochrome c oxidase [Mus musculus]
>gi| 1094404 Iprf I I2106151A cytochrome c oxidase : SUBUNIT=VIa [Mus musculus]
- % Identity: 41.4
- Alignment Length: 106 - Location of Alignment in SEQ ID NO 482: from 1 to
99
Maximum Length Sequence: Public Genomic DNA: gi No: 4584531 Predicted Exons: INTR 56873 ... 56641 OCKHAMG-CDNA
INTR 56627 .. . 56451 OCKHAMG-CDNA
SINGLE 56812 56645 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 483
- Ceres seq id 2051906
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 484
- Ceres seq_id 2051907
- Location of start within SEQ ID NO 483: at 2 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 322
- gi No. 4850407
- Description: (AC007357) EST gb|T21221 comes from this gene. [Arabidopsis thaliana]
- % Identity: 57.1
- Alignment Length: 35
- Location of Alignment in SEQ ID NO 484: from 37 to 70
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 485 - Ceres seq_id 2051908
- Location of start within SEQ ID NO 483: at 62 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide ( s ) (Dp) Related Amino Acid Sequences
- Alignment No. 323
- gi No. 4850407
- Description: (AC007357) EST gb|T21221 comes from this gene. [Arabidopsis thaliana] - % Identity: 57.1
- Alignment Length: 35
- Location of Alignment in SEQ ID NO 485: from 17 to 50 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 486
- Ceres seq__id 2051909
- Location of start within SEQ ID NO 483: at 74 nt , (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 324
- gi No. 4850407
- Description: (AC007357) EST gb|T21221 comes from this gene. [Arabidopsis thaliana]
- % Identity: 57.1
- Alignment Length: 35
- Location of Alignment in SEQ ID NO 486: from 13 to 46
Maximum Length Sequence: Public Genomic DNA: gi No: 4584841
Predicted Exons:
INTR 75983 .. 75751 OCKHAMG- -CDNA INTR 75412 .. 74936 OCKHAMG--CDNA
INTR 75992 .. 75751 OCKHAMG- -CDNA INTR 75412 .. 75090 OCKHAMG--CDNA
INIT 75937 .. 75751 OCKHAMG- -CDS TERM 75412 .. 75132 OCKHAMG--CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 487 - Ceres seq_id 2052403
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 488
- Ceres seq_id 2052404
- Location of start within SEQ ID NO 487: at 56 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Pathogenesis-related protein Bet v I family
- Location within SEQ ID NO 488: from 5 to 155 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 325
- gi No. 1321731
- Description: (Z72439) major allergen Cor a 1 [Corylus avellana]
- % Identity: 36.3 - Alignment Length: 159
- Location of Alignment in SEQ ID NO 488: from 5 to 155
Maximum Length Sequence: Public Genomic DNA: gi No: 4699904 redicted Exons
INTR 82618 52845 OCKHAMG-CDNA
INTR 83226 53301 OCKHAMG-CDNA
INTR 83389 .3561 OCKHAMG-CDNA
INTR 84124 54385 OCKHAMG-CDNA
INIT 82730 52845 OCKHAMG-CDS
INTR 83226 53301 OCKHAMG-CDS
INTR 83389 53561 OCKHAMG-CDS
TERM 84124 54199 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 489
- Ceres seq id 2053545
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 490
- Ceres seq_id 2053546
- Location of start within SEQ ID NO 489: at 113 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 490: at 36 aa .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- MAPEG family
- Location within SEQ ID NO 490: from 59 to 136 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 326
- gi No. 4758714
- Description: ref I NP_004519.11 pMGST3 microsomal glutathione S-transferase 3 >gi 12583081 AF026977) microsomal glutathione S-transferase 3 [Homo sapiens] - % Identity: 41.9
- Alignment Length: 131
- Location of Alignment in SEQ ID NO 490: from 8 to 136 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 491
- Ceres seq_id 2053547
- Location of start within SEQ ID NO 489: at 197 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- MAPEG family
- Location within SEQ ID NO 491: from 31 to 108 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 327 - gi No. 4758714
- Description: ref I NP_004519.1 | pMGST3 | microsomal glutathione S-transferase 3 >gi 12583081 (AF026977) microsomal glutathione S-transferase 3 [Homo sapiens] - % Identity: 41.9
- Alignment Length: 131
- Location of Alignment in SEQ ID NO 491: from 1 to 108 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 492
- Ceres seq_id 2053548
- Location of start within SEQ ID NO 489: at 329 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 492: at 22 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- MAPEG family
- Location within SEQ ID NO 492: from 1 to 64 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 328
- gi No. 4758714 - Description: ref | NP_004519.11 pMGST3 | microsomal glutathione S-transferase 3 >gi 12583081 (AF026977) microsomal glutathione S-transferase 3 [Homo sapiens]
- % Identity: 41.9
- Alignment Length: 131 - Location of Alignment in SEQ ID NO 492: from 1 to
64
Maximum Length Sequence: related to:
Clone IDs:
2004
31675
266907
Public Genomic DNA: gi No: 4887737
Predicted Exons:
INTR 7907 ... 8579 OCKHAMG-CDNA
INTR 7913 ... 8587 OCKHAMG-CDNA
INTR 7911 ... 8579 OCKHAMG-CDNA
INTR 7909 ... 8579 OCKHAMG-CDNA
INTR 7913 ... 8578 OCKHAMG-CDNA INTR 7913 8509 OCKHAMG-CDNA
SINGLE 7958 ... 8425 OCKHAMG-CDS gi No: 5019264 Predicted Exons:
SINGLE 4143 ... 4610 GENBANK
INTR 4092 4764 OCKHAMG-CDNA
INTR 4098 4772 OCKHAMG-CDNA
INTR 4096 4764 OCKHAMG-CDNA
INTR 4094 4764 OCKHAMG-CDNA
INTR 4098 4763 OCKHAMG-CDNA
INTR 4098 4694 OCKHAMG-CDNA SINGLE 4143 ... 4610 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 493
- Ceres seq_id 2053884
- Alternative transcription start site(s) located in SEQ ID NO 493:
-47,-3,2,3,4,5,6,7,8,10,11,12,13,14,15,16,20,21,28,29 38,44,45, 60,68
- Clone 2004 starts at 1 and ends at 677 in cDNA.
- Clone 31675 starts at 3 and ends at 607 in cDNA. - Clone 266907 starts at 4 and ends at 677 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 494
- Ceres seq_id 2053885
- Location of start within SEQ ID NO 493: at 1 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 329
- gi No. 2498177
- Description: BASP1 PROTEIN
- % Identity: 28
- Alignment Length: 164 - Location of Alignment in SEQ ID NO 494: from 2 to
159
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 495
- Ceres seq_id 2053886
- Location of start within SEQ ID NO 493: at 52 nt , (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 330
- gi No. 2498177
- Description: BASP1 PROTEIN
- % Identity: 28
- Alignment Length: 164
- Location of Alignment in SEQ ID NO 495: from 1 to 142
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 496
- Ceres seq_id 2053887
- Location of start within SEQ ID NO 493 at 172 nt.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 331
- gi No. 2498177
- Description: BASP1 PROTEIN
- % Identity: 28 - Alignment Length: 164
- Location of Alignment in SEQ ID NO 496: from 1 to 102
Maximum Length Sequence: Public Genomic DNA: gi No: 4887738 Predicted Exons: INTR 45004 . 44725 OCKHAMG-CDNA INTR 44038 . 43918 OCKHAMG-CDNA INTR 43839 . 43444 OCKHAMG-CDNA
INIT 44942 44725 OCKHAMG-CDS INTR 44038 43918 OCKHAMG-CDS TERM 43839 43564 OCKHAMG-CDS gi No: 5103850 Predicted Exons INIT 44944 44727 GENBANK INTR 44040 43920 GENBANK TERM 43841 43566 GENBANK
INTR 45006 44727 OCKHAMG-CDNA INTR 44040 43920 OCKHAMG-CDNA INTR 43841 43446 OCKHAMG-CDNA
INIT 44944 44727 OCKHAMG-CDS INTR 44040 43920 OCKHAMG-CDS 232 TERM 43841 ... 43566 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 497
- Ceres seq id 2053908
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 498 - Ceres seq_id 2053909
- Location of start within SEQ ID NO 497: at 63 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide ( s) (Dp) elated Amino Acid Sequences
- Alignment No. 332
- gi No. 2245000
- Description: (Z97341) LET1 like protein [Arabidopsis thaliana] - % Identity: 31.4
- Alignment Length: 156
- Location of Alignment in SEQ ID NO 498: from 17 to 164 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 499
- Ceres seq_id 2053910
- Location of start within SEQ ID NO 497: at 168 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 499: at 23 aa.
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 333
- gi No. 2245000
- Description: (Z97341) LET1 like protein [Arabidopsis thaliana]
- % Identity: 31.4 - Alignment Length: 156
- Location of Alignment in SEQ ID NO 499: from 1 to 129
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 500
- Ceres seq_id 2053911
- Location of start within SEQ ID NO 497: at 216 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 334
- gi No. 2245000
- Description: (Z97341) LET1 like protein [Arabidopsis thaliana]
- % Identity: 31.4
- Alignment Length: 156
- Location of Alignment in SEQ ID NO 500: from 1 to 113
Maximum Length Sequence Public Genomic DNA: gi No: 4335711 Predicted Exons :
INTR 46239 .. . 46470 OCKHAMG- -CDNA
INTR 46624 .. . 46739 OCKHAMG- -CDNA
INTR 47125 .. . 47428 OCKHAMG- -CDNA
INIT 46285 .. . 46470 OCKHAMG- -CDS
INTR 46624 .. . 46739 OCKHAMG- -CDS
TERM 47125 .. . 47413 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 501
- Ceres seq id 2056123
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 502
- Ceres seq_id 2056124
- Location of start within SEQ ID NO 501: at 47 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Zinc finger, C3HC4 type (RING finger)
- Location within SEQ ID NO 502: from 150 to 190 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 335 - gi No. 3790593
- Description: (AF079185) RING-H2 finger protein RHYla [Arabidopsis thaliana]
- % Identity: 55.1
- Alignment Length: 49 - Location of Alignment in SEQ ID NO 502: from 146 to 194
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 503
- Ceres seq__id 2056125
- Location of start within SEQ ID NO 501: at 56 nt (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Zinc finger, C3HC4 type (RING finger) - Location within SEQ ID NO 503: from 147 to 187 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 336 - gi No. 3790593
- Description: (AF079185) RING-H2 finger protein RHYla [Arabidopsis thaliana]
- % Identity: 55.1
- Alignment Length: 49 - Location of Alignment in SEQ ID NO 503: from 143 to 191
Maximum Length Sequence Public Genomic DNA: gi No: 4432829 Predicted Exons: INTR 51185 .. 51056 OCKHAMG-CDNA INTR 50590 . 50253 OCKHAMG-CDNA
INIT 56176 55097 OCKHAMG-CDS
INTR 55014 54161 OCKHAMG-CDS
INTR 54076 54011 OCKHAMG-CDS
INTR 51530 51382 OCKHAMG-CDS
INTR 51187 51056 OCKHAMG-CDS
TERM 50590 50418 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 504
- Ceres seq id 2056245
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 505
- Ceres seq_id 2056246
- Location of start within SEQ ID NO 504 at 1 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 337
- gi No. 4938484
- Description: (AL078464) transcription factor-like protein [Arabidopsis thaliana]
- % Identity: 56.2 - Alignment Length: 661 - Location of Alignment in SEQ ID NO 505: from 4 to 644
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 506
- Ceres seq_id 2056247
- Location of start within SEQ ID NO 504: at 55 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 338
- gi No. 4938484
- Description: (AL078464) transcription factor-like protein [Arabidopsis thaliana]
- % Identity: 56.2
- Alignment Length: 661
- Location of Alignment in SEQ ID NO 506: from 1 to 626
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 507
- Ceres seq_id 2056248
- Location of start within SEQ ID NO 504: at 751 nt
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 339 - gi No. 4938484
- Description: (AL078464) transcription factor-like protein [Arabidopsis thaliana]
- % Identity: 56.2
- Alignment Length: 661 - Location of Alignment in SEQ ID NO 507: from 1 to
394
Maximum Length Sequence: related to: Clone IDs:
213322 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 508
- Ceres seq_id 1941142
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 509
- Ceres seq_id 1941143 - Location of start within SEQ ID NO 508: at 119 nt . (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L24e
- Location within SEQ ID NO 509: from 3 to 73 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 340
- gi No. 1710521
- Description: 60S RIBOSOMAL PROTEIN L24 >gi| 1154859|emb|CAA63960 I (X94296) L24 ribosomal protein [Hordeum vulgare]
- % Identity: 94.4
- Alignment Length: 162
- Location of Alignment in SEQ ID NO 509: from 1 to 161
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 510
- Ceres seq_id 1941144 - Location of start within SEQ ID NO 508: at 284 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 341
- gi No. 1710521
- Description: 60S RIBOSOMAL PROTEIN L24
>gi| 1154859|emb|CAA63960 I (X94296) L24 ribosomal protein [Hordeum vulgare] - % Identity: 94.4
- Alignment Length: 162
- Location of Alignment in SEQ ID NO 510: from 1 to 106 Maximum Length Sequence: related to: Clone IDs:
241379 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 511
- Ceres seq_id 1942975
- Alternative transcription start site(s) located in SEQ ID NO 511:
29,30,31,32,33,36
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 512
- Ceres seq_id 1942976
- Location of start within SEQ ID NO 511: at 1 nt (C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 512: from 149 to 233 aa .
(Dp) Related Amino Acid Sequences
- Alignment No. 342
- gi No. 133940 - Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 708511 pir M R3XL3A ribosomal protein S3a - African clawed frog >gi| 65091 | emb | CAA40592 | (X57322) ribosomal protein Sla [Xenopus laevis]
- % Identity: 82.5 - Alignment Length: 223
- Location of Alignment in SEQ ID NO 512: from 46 to 268
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 513
- Ceres seq_id 1942977
- Location of start within SEQ ID NO 511: at 136 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 513: from 104 to 188 aa . (Dp) Related Amino Acid Sequences
- Alignment No. 343
- gi No. 133940
- Description: 40S RIBOSOMAL PROTEIN S3A (S1A)
>gi I 70851 Ipir I I R3XL3A ribosomal protein S3a - African clawed frog >gi | 650911 emb I CAA40592 | (X57322) ribosomal protein Sla [Xenopus laevis]
- % Identity: 82.5
- Alignment Length: 223
- Location of Alignment in SEQ ID NO 513: from 1 to 223
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 514
- Ceres seq_id 1942978 - Location of start within SEQ ID NO 511: at 205 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain. - Location within SEQ ID NO 514: from 81 to 165 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 344
- gi No. 133940
- Description: 40S RIBOSOMAL PROTEIN S3A (S1A) >gi I 70851 I pir I I R3XL3A ribosomal protein S3a - African clawed frog >gi| 65091 | emb | CAA40592 I (X57322) ribosomal protein Sla [Xenopus laevis]
- % Identity: 82.5
- Alignment Length: 223 - Location of Alignment in SEQ ID NO 514: from 1 to
200
Maximum Length Sequence: related to: Clone IDs:
289536 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 515
- Ceres seq_id 1944349
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 516
- Ceres seq_id 1944350 - Location of start within SEQ ID NO 515: at 423 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L24e - Location within SEQ ID NO 516: from 3 to 73 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 345
- gi No. 1710521 - Description: 60S RIBOSOMAL PROTEIN L24
>gi| 1154859|emb|CAA63960 I (X94296) L24 ribosomal protein [Hordeum vulgare]
- % Identity: 94.4
- Alignment Length: 162 - Location of Alignment in SEQ ID NO 516: from 1 to
161
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 517 - Ceres seq_id 1944351
- Location of start within SEQ ID NO 515: at 588 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) (Dp) Related Amino Acid Sequences
- Alignment No. 346 - gi No. 1710521
- Description: 60S RIBOSOMAL PROTEIN L24
>gi I 1154859 | emb | CAA63960 | (X94296) L24 ribosomal protein [Hordeum vulgare] - % Identity: 94.4
- Alignment Length: 162
- Location of Alignment in SEQ ID NO 517: from 1 to 106 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 518
- Ceres seq_id 1944352
- Location of start within SEQ ID NO 515: at 736 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 347
- gi No. 1362587 - Description: spermatid-specific protein T2 precursor - longfin squid
- % Identity: 55.8
- Alignment Length: 52
- Location of Alignment in SEQ ID NO 518: from 1 to 46
Maximum Length Sequence: related to: Clone IDs: 291258
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 519
- Ceres seq_id 1964011
- Alternative transcription start site(s) located in SEQ ID NO 519:
4,34,37,38,39,40,41
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 520 - Ceres seq_id 1964012
- Location of start within SEQ ID NO 519: at 3 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s) - Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 520: from 150 to 234 aa .
(Dp) Related Amino Acid Sequences - Alignment No. 348
- gi No. 1173253 - Description: 40S RIBOSOMAL PROTEIN S3 >gi I 543317 I pir I I S41170 ribosomal protein S3 - mouse >gi 157728 | emb | CAA35916 I (X51536) ribosomal protein S3 (AA 1- 243) [Rattus rattus] >gi I 439522 | emb I CAA54167 | (X76772) ribosomal protein S3 [Mus musculus]
- % Identity: 81.1
- Alignment Length: 227
- Location of Alignment in SEQ ID NO 520: from 47 to 273
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 521
- Ceres seq_id 1964013
- Location of start within SEQ ID NO 519: at 141 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 521: from 104 to 188 aa.
(Dp) Related Amino Acid Sequences
- Alignment No. 349
- gi No. 1173253 - Description: 40S RIBOSOMAL PROTEIN S3
>gi I 543317 I pir I I S41170 ribosomal protein S3 - mouse >gi|57728 | emb | CAA35916 | (X51536) ribosomal protein S3 (AA 1- 243) [Rattus ,attus] >gi I 439522 | emb | CAA54167 | (X76772) ribosomal protein S3 [Mus musculus] - % Identity: 81.1
- Alignment Length: 227
- Location of Alignment in SEQ ID NO 521: from 1 to 227 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 522
- Ceres seq_id 1964014
- Location of start within SEQ ID NO 519: at 210 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
- Ribosomal protein S3, C-terminal domain.
- Location within SEQ ID NO 522: from 81 to 165 aa. (Dp) Related Amino Acid Sequences
- Alignment No. 350
- gi No. 1173253
- Description: 40S RIBOSOMAL PROTEIN S3 >gi I 543317 Ipir I I S41170 ribosomal protein S3 - mouse >gi|57728 | emb | CAA35916 I (X51536) ribosomal protein S3 (AA 1- 243) [Rattus rattus] >gi I 439522 | emb | CAA54167 | (X76772) ribosomal protein S3 [Mus musculus]
- % Identity: 81.1
- Alignment Length: 227 - Location of Alignment in SEQ ID NO 522: from 1 to
204
Maximum Length Sequence: related to: Clone IDs:
207986 224937 227089 229580 241662
275880 278084 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 523 - Ceres seq_id 1983854
- Alternative transcription start site(s) located in SEQ ID NO 523:
-1,2, 6,30,31,32,33,34,36
- Clone 207986 starts at 31 and ends at 810 in cDNA. - Clone 224937 starts at 31 and ends at 810 in cDNA.
- Clone 227089 starts at 33 and ends at 804 in cDNA.
- Clone 229580 starts at 31 and ends at 821 in cDNA.
- Clone 241662 starts at 34 and ends . 815 in cDNA.
- Clone 275880 starts at 1 and ends at 804 in cDNA. - Clone 278084 starts at 31 and ends at 815 in cDNA.
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 524
- Ceres seq_id 1983855
- Location of start within SEQ ID NO 523: at 315 nt ,
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences - Alignment No. 351
- gi No. 1710521
- Description: 60S RIBOSOMAL PROTEIN L24
>gi| 1154859|emb|CAA63960 I (X94296) L24 ribosomal protein [Hordeum vulgare] - % Identity: 94
- Alignment Length: 150
- Location of Alignment in SEQ ID NO 524: from 1 to 106 Maximum Length Sequence: related to: Clone I Ds :
221977 226126 293001 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 525
- Ceres seq_id 1990261
- Alternative transcription start site(s) located in SEQ ID NO 525: 16,30,32
- Clone 226126 starts at 30 and ends at 772 in cDNA.
- Clone 293001 starts at 32 and ends at 810 in cDNA.
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 526
- Ceres seq_id 2061972
- Location of start within SEQ ID NO 525: at 144 nt .
(C) Nomination and Annotation of Domains within Predicted Polypeptide (s)
- Ribosomal protein L24e
- Location within SEQ ID NO 526: from 3 to 73 aa.
(Dp) Related Amino Acid Sequences - Alignment No. 352
- gi No. 1710521
- Description: 60S RIBOSOMΓL PROTEIN L24
>gi I 1154859|emb|CAA63960 I (X94296) L2<, ribosomal protein [Hordeum vulgare] - % Identity: 94.4
- Alignment Length: 162
- Location of Alignment in SEQ ID NO 526: from 1 to 161 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 527
- Ceres seq_id 2061973
- Location of start within SEQ ID NO 525: at 309 nt . (C) Nomination and Annotation of Domains within
Predicted Polypeptide (s)
(Dp) Related Amino Acid Sequences
- Alignment No. 353
- gi No. 1710521 - Description: 60S RIBOSOMAL PROTEIN L24
>gi I 1154859|emb|CAA63960| (X94296) L24 ribosomal protein [Hordeum vulgare]
- % Identity: 94.4
- Alignment Length: 162 - Location of Alignment in SEQ ID NO 527: from 1 to
106 REF TABLE 2
Maximum Length Sequence: related to: Clone IDs: 9458 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 1
- Ceres seq_id 1007802 - Alternative transcription start site(s) located in SEQ ID NO 1:
2,3,4
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 2
- Ceres seq_id 1007803
- Location of start within SEQ ID NO 1: at 3 nt.
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 3
- Ceres seq_id 1007804
- Location of start within SEQ ID NO 1: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 3: at 29 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 4
- Ceres seq_id 1007805
- Location of start within SEQ ID NO 1: at 29 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 4: at 20 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 8458 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 5
- Ceres seq_id 1008556 - Alternative transcription start site(s) located in SEQ ID NO 5:
80,103,134,135,136,137,138,139,152,153,157,166,168
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 6
- Ceres seq id 1008557 Location of start within SEQ ID NO 5: at 173 nt .
Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene
Maximum Length Sequence: related to: Clone IDs: 8384 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 7
- Ceres seq_id 1008628
- Alternative transcription start site(s) located in SEQ ID NO 7:
3,28
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 8
- Ceres seq_id 1008629
- Location of start within SEQ ID NO 7: at 41 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 7260 Public Genomic DNA: gi No: 5733889 Predicted Exons: INIT 21286 ., 21509 GENBANK INTR 21606 . 21832 GENBANK TERM 21951 . , 21958 GENBANK
INIT 21286 21509 OCKHAMG-CDS
INTR 21606 21832 OCKHAMG-CDS
TERM 21951 21958 OCKHAMG-CDS gi No: 6041810
Predicted Exons :
INIT 34915 35138 OCKHAMG-CDS
INTR 35235 35461 OCKHAMG-CDS
TERM 35580 35587 OCKHAMG-CDS gi No: 6091711
Predicted Exons :
INIT 100255 100478 OCKHAMG-CDS
INTR 100575 100801 OCKHAMG-CDS TERM 100920... 100927 OCKHAMG--CDS gi No: 6102641 Predicted Exons:
INIT 91941 ... 92164 OCKHAMG- -CDS
INTR 92261 ... 92487 OCKHAMG- -CDS
TERM 92606 ... 92613 OCKHAMG- -CDS gi No: 6453849 Predicted Exons :
INIT 19658 ... 19435 OCKHAMG- -CDS
INTR 19338 ... 19112 OCKHAMG- -CDS
TERM 18993 ... 18986 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 9
- Ceres seq_id 1009376
- Alternative transcription start site(s) located in SEQ
ID NO 9:
4,7,22,48,56,77
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 10
- Ceres seq_id 1009377
- Location of start within SEQ ID NO 9: at 238 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 10: at 76 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 11
- Ceres seq_id 1009378
- Location of start within SEQ ID NO 9: at 334 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 11: at 44 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 12 - Ceres seq_id 1009379
- Location of start within SEQ ID NO 9: at 245 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 12: at 47 aa.
Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene
Maximum Length Sequence: related to: Clone IDs: 4489 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 13 - Ceres seq_id 1011128
- Alternative transcription start site(s) located in SEQ ID NO 13:
6,7
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 14
- Ceres seq_id 1011129
- Location of start within SEQ ID NO 13: at 41 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 15
- Ceres seq_id 1011130
- Location of start within SEQ ID NO 13: at 59 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant speciπc gene.
Maximum Length Sequence: related to: Clone IDs: 42241
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 16
- Ceres seq id 1011718
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 17
- Ceres seq_id 1011719
- Location of start within SEQ ID NO 16: at 3 nt ,
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 18
- Ceres seq_id 1011720
- Location of start within SEQ ID NO 16: at 78 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 18: at 21 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 19 - Ceres seq_id 1011721
- Location of start within SEQ ID NO 16: at 102 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs: 42200
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 20 - Ceres seq_id 1011735
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 21
- Ceres seq_id 1011736 - Location of start within SEQ ID NO 20: at 75 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 22
- Ceres seq_id 1011737 - Location of start within SEQ ID NO 20: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 22: at 37 aa.
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 23
- Ceres seq_id 1011738
- Location of start within SEQ ID NO 20: at 2 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
42217 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 24 - Ceres seq_id 1011755
- Alternative transcription start site(s) located in SEQ ID NO 24:
34 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 25
- Ceres seq_id 1011756
- Location of start within SEQ ID NO 24: at 1 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 26 - Ceres seq_id 1011757
- Location of start within SEQ ID NO 24: at 19 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
42034 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 27 - Ceres seq_id 1011832
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NC 28
- Ceres seq_id 1011833 - Location of start with SEQ ID NO 27: at 97 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 29
- Ceres seq_id 1011834 - Location of start within SEQ ID NO 27: at 100 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 30
- Ceres seq_id 1011835 - Location of start within SEQ ID NO 27: at 106 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant speciric gene
Maximum Length Sequence: related to: Clone IDs:
41812 Public Genomic DNA: gi No: 6434227 Predicted Exons:
INIT 65854 ... 65974 OCKHAMG-CDS TERM 66067 ... 66206 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 31
- Ceres seq_id 1011907
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 32
- Ceres seq_id 1011908
- Location of start within SEQ ID NO 31: at 218 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 32: at 30 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 33
- Ceres seq_id 1011909
- Location of start within SEQ ID NO 31: at 239 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 33: at 23 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 34
- Ceres seq_id 1011910
- Location of start within SEQ ID NO 31: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 34: at 17 aa .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
41828 Public Genomic DNA: gi No: 4159707
Predicted Exons:
INTR 15084 ... 15201 OCKHAMG-CDNA INTR 15295 ... 15324 OCKHAMG-CDNA INTR 15414 ... 15533 OCKHAMG-CDNA INTR 15648 ... 15956 OCKHAMG-CDNA
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 35
- Ceres seq_id 1011911
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 36
- Ceres seq_id 1011912
- Location of start within SEQ ID NO 35 at 194 nt,
IB) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 37
- Ceres seq_id 1011913
- Location of start within SEQ ID NO 35: at 230 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 37: at 22 aa. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 38
- Ceres seq_id 1011914 - Location of start within SEQ ID NO 35: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 38: at 28 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
41723 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 39 - Ceres seq id 1011954
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 40
- Ceres seq_id 1011955
- Location of start within SEQ ID NO 39: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 40: at 40 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 41
- Ceres seq_id 1011956
- Location of start within SEQ ID NO 3! at 107 nt
(Ba) Polypeptide Activities: Similar to DNAJ Protein Activities
Maximum Length Sequence: related to: Clone IDs:
41730 Public Genomic DNA: gi No: 4678371 Predicted Exons:
SINGLE 48996 ... 49184 GENBANK
SINGLE 48996 ... 49184 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 42
- Ceres seq id 1011960 - Alternative transcription start site(s) located in SEQ ID NO 42:
20,22,25,43 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 43
- Ceres seq_id 1011961
- Location of start within SEQ ID NO 42: at 69 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 44
- Ceres seq_id 1011962
- Location of start within SEQ ID NO 42: at 78 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 45
- Ceres seq_id 1011963
- Location of start within SEQ ID NO 42: at 90 nt . (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene, similar to serine rich protein activities .
Maximum Length Sequence: related to: Clone IDs: 38977 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 46
- Ceres seq_id 1014075
- Alternative transcription start site(s) located in SEQ ID NO 46: -3, -2, -1,2, 3, 4, 5, 6, 7, 8, 10, 15, 103
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 47
- Ceres seq_id 1014076 - Location of start within SEQ ID NO 46: at 1 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 48
- Ceres seq_id 1014077 - Location of start within SEQ ID NO 46: at 84 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 48: at 22 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene
Maximum Length Sequence: related to: Clone IDs:
37081 Public Genomic DNA: gi No: 4159707 Predicted Exons:
INIT 15458 ... 15533 OCKHAMG-CDS TERM 15648 ... 15751 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 49 - Ceres seq_id 1015865
- Alternative transcription start site(s) located in SEQ ID NO 49:
-29
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 50
- Ceres seq_id 1015866
- Location of start within SEQ ID NO 49: at 281 nt (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 51
- Ceres seq_id 1015867
- Location of start within SEQ ID NO 49: at 317 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 51: at 22 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 52
- Ceres seq_id 1015868
- Location of start within SEQ ID NO 49: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 52: at 15 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
29375 Public Genomic DNA: gi No: 4159707 Predicted Exons:
INTR 15158 .. 15201 OCKHAMG-CDNA INTR 15449 ... 15533 OCKHAMG-CDNA INTR 15648 ... 15947 OCKHAMG-CDNA (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 53
- Ceres seq_id 1021371
- Alternative transcription start site(s) located in SEQ ID NO 53:
-74
IB) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 54
- Ceres seq_id 1021372
- Location of start within SEQ ID NO 53: at 3 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 55
- Ceres seq_id 1021373
- Location of start within SEQ ID NO 53: at 54 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 56
- Ceres seq_id 1021374
- Location of start within SEQ ID NO 53: at 90 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 56: at 22 aa.
Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: related to: Clone IDs: 27064
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 57
- Ceres seq_id 1022578
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 58
- Ceres seq_id 1022579
- Location of start within SEQ ID NO 57: at 1 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 59
- Ceres seq_id 1022580
- Location of start within SEQ ID NO 57: at 157 nt ,
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 60
- Ceres seq_id 1022581
- Location of start within SEQ ID NO 57: at 10 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence related to:
Clone IDs:
23773
Public Genomic DNA: gi No: 6136357
Predicted Exons:
INTR 51972 . 51830 OCKHAMG-CDNA
INTR 51129 . 51055 OCKHAMG-CDNA
INTR 50948 . 50806 OCKHAMG-CDNA
INTR 50706 . 50608 OCKHAMG-CDNA
INTR 50326 . 50147 OCKHAMG-CDNA gi No: 6143858
Predicted Exons
INTR 51972 51830 OCKHAMG-CDNA INTR 51129 51055 OCKHAMG-CDNA INTR 50948 50806 OCKHAMG-CDNA INTR 50706 50608 OCKHAMG-CDNA INTR 50326 50147 OCKHAMG-CDNA
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 61
- Ceres seq_id 102424 0
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 62
- Ceres seq_id 1024241
- Location of start within SEQ ID NO 61: at 54 nt
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 63
- Ceres seq_id 1024242
- Location of start within SEQ ID NO 61: at 66 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 64
- Ceres seq_id 1024243
- Location of start within SEQ ID NO 61: at 404 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence related to: Clone IDs: 2030 Public Genomic DNA: gi No: 5441914 Predicted Exons:
SINGLE 4802 4449 OCKHAMG-CDS gi No: 5881519 Predicted Exons : SINGLE 4802 . 4449 GENBANK
SINGLE 4802 ... 4449 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 65
- Ceres seq_id 1026562
- Alternative transcription start site(s) located in SEQ ID NO 65: 36,41,43,44,88,90,94,102
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 66
- Ceres seq_id 1026563
- Location of start within SEQ ID NO 65: at 1 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 66: at 51 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 67
- Ceres seq_id 1026564
- Location of start within SEQ ID NO 65: at 109 n .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 67: at 15 aa .
(Ba) Polypeptide Activities: Similar to cytochrome c oxidase II activities . Maximum Length Sequence: related to: Clone IDs:
20097 Public Genomic DNA: gi No: 5733893
Predicted Exons: INTR 66948 . 67429 OCKHAMG-CDNA
SINGLE 66986 67324 OCKHAMG-CDS gi No: 5748882 Predicted Exons: INTR 41416 40935 OCKHAMG-CDNA
SINGLE 41380 41042 OCKHAMG-CDS gi No: 5801671 Predicted Exons
INTR 51184 50703 OCKHAMG-CDNA
SINGLE 51148 50810 OCKHAMG-CDS gi No: 5809708
Predicted Exons
INTR 41416 40935 OCKHAMG-CDNA
SINGLE 41380 41042 OCKHAMG-CDS gi No: 5836114 Predicted Exons:
INTR 42487 42006 OCKHAMG-CDNA
SINGLE 42451 ... 42113 )CKHAMG-CDS gi No: 5923662 Predicted Exons:
INTR 43106 ... 43587 OCKHAMG-CDNA
SINGLE 43144 ... 43482 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 68
- Ceres seq_id 1026648
- Alternative transcription start site(s) located in SEQ ID NO 68:
-74,-72,-48,-42,76
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 69
- Ceres seq_id 1026649
- Location of start within SEQ ID NO 68: at 39 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 69: at 59 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 70 - Ceres seq_id 1026650
- Location of start within SEQ ID NO 68: at 78 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 70: at 46 aa. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 71
- Ceres seq__id 1026651
- Location of start within SEQ ID NO 68: at 81 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 71: at 45 aa. (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 18274 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 72
- Ceres seq_id 1027881
- Alternative transcription start site(s) located in SEQ ID NO 72: -8,-4,2
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 73
- Ceres seq_id 1027882 - Location of start within SEQ ID NO 72: at 3 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 74
- Ceres seq_id 1027883 - Location of start within SEQ ID NO 72: at 36 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 75
- Ceres seq_id 1027884 - Location of start within SEQ ID NO 72: at 105 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 75: at 18 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
121894 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 76 - Ceres seq_id 1381797
- Alternative transcription start site(s) located in SEQ ID NO 76:
-41,18,19,22,26 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 77 - Ceres seq_id 1381798
- Location of start within SEQ ID NO 76: at 70 nt .
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 78
- Ceres seq_id 1381799
- Location of start within SEQ ID NO 76: at 82 nt .
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 79
- Ceres seq_id 1381800
- Location of start within SEQ ID NO 76: at 109 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
31667 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 80 - Ceres seq_id 1442747
- Alternative transcription start site(s) located in SEQ ID NO 80:
3,5,6,11,62,64,65,66,69,70,71,72,74 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 81
- Ceres seq_id 1442748
- Location of start within SEQ ID NO 80: at 2 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 82
- Ceres seq_id 1442749
- Location of start within SEQ ID NO 80: at 140 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 83
- Ceres seq_id 1442750
- Location of start within SEQ ID NO 80: at 224 nt . (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs:
270354 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 84
- Ceres seq_id 1459199
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 85 - Ceres seq_id 1459200
- Location of start within SEQ ID NO 84: at 2 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 86 - Ceres seq_id 1459201
- Location of start within SEQ ID NO 84: at 56 nt .
- Location of Signal Peptide cleavage Site within SEQ ID NO 86: at 20 aa. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 87
- Ceres seq_id 1459202
- Location of start within SEQ ID NO 84: at 80 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 87: at 17 aa .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
12250 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 88
- Ceres seq_id 1565605
- Alternative transcription start site(s) located in SEQ ID NO 88:
-17
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 89
- Ceres seq_id 1565606
- Location of start within SEQ ID NO 88: at 133 nt
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 90
- Ceres seq_id 1565607
- Location of start within SEQ ID NO 88: at 181 nt . (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs:
97883 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 91
- Ceres seq_id 1566686
- Alternative transcription start site(s) located in SEQ ID NO 91:
58, 61
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 92
- Ceres seq_id 1566687
- Location of start within SEQ ID NO 91: at 137 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 12408 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 93
- Ceres seq_id 1567367
- Alternative transcription start site(s) located in SEQ ID NO 93: -39, 6, 11, 14, 17, 25, 32, 33, 34, 35, 60
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 94
- Ceres seq_id 1567368 - Location of start within SEQ ID NO 93: at 1 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 95
- Ceres seq__id 1567369 - Location of start within SEQ ID NO 93: at 2 nt . ;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 96
- Ceres seq_id 1567370
- Location of start within SEQ ID NO 93: at 65 nt.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene
Maximum Length Sequence: related to:
Clone IDs: 19528
Public Genomic DNA: gi No: 6091770 Predicted Exons:
INIT 21323 ... 21390 OCKHAMG-CDS
INTR 21467 ... 21564 OCKHAMG-CDS
INTR 21995 ... 22027 OCKHAMG-CDS
TERM 22386 ... 22468 OCKHAMG-CDS gi No: 6102636
Predicted Exons :
INIT 21323 ... 21390 OCKHAMG-CDS
INTR 21467 ... 21564 OCKHAMG-CDS
INTR 21995 ... 22027 OCKHAMG-CDS
TERM 22386 ... 22468 OCKHAMG-CDS gi No: 6137907
Predicted Exons :
INIT 21252 ... 21319 OCKHAMG-CDS
INTR 21396 ... 21493 OCKHAMG-CDS
INTR 21924 ... 21956 OCKHAMG-CDS
TERM 22315 ... 22397 OCKHAMG-CDS gi No: 6437519
Predicted Exons :
INIT 14107 ... 14174 OCKHAMG-CDS
INTR 14251 ... 14348 OCKHAMG-CDS
INTR 14779 ... 14811 OCKHAMG-CDS
TERM 15170 ... 15252 OCKHAMG-CDS
(Ac ) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 97
- Ceres seq id 1570101
- Alternative transcription start site(s) located in SEQ
ID NO 97:
9,29,30, 31,32,39,40 ,43,44, 61,62, 64,65,198
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 98
- Ceres seq_id 1570102
- Location of start within SEQ ID NO 97: at 116 nt . Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: related to: Clone IDs:
42399 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 99
- Ceres seq id 1571051
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 100
- Ceres seq_id 1571052
- Location of start within SEQ ID NO 99: at 1 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 101
- Ceres seq_id 1571053
- Location of start within SEQ ID NO 99: at 16 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 101: at 30 aa.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 102
- Ceres seq_id 1571054
- Location of start within SEQ ID NO 99: at 139 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 6487 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 103
- Ceres seq_id 1571100
- Alternative transcription start site(s) located in SEQ ID NO 103: 5,6
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 104
- Ceres seq_id 1571101 - Location of start within SEQ ID NO 103: at 1 nt . - Location of Signal Peptide Cleavage Site within SEQ ID NO 104: at 19 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 105 - Ceres seq_id 1571102
- Location of start within SEQ ID NO 103: at 82 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 39977 14890 34623 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 106
- Ceres seq_id 1665272
- Alternative transcription start site(s) located in SEQ ID NO 106: 3, 15, 32, 33, 34, 35, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 7, 48, 49, 50 51, 60, 61, 63, 66, 69, 70, 71, 72, 74, 75, 76, 78, 79, 84, 85
- Clone 39977 starts at 35 and ends at 636 in cDNA.
- Clone 14890 starts at 43 and ends at in cDNA.
- Clone 34623 starts at 1 and ends at 598 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 107
- Ceres seq_id 1665273
- Location of start within SEQ ID NO 106: at 90 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs: 24562 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 108
- Ceres seq_id 1713895
- Alternative transcription start site(s) located in SEQ ID NO 108: -7,2,3,5,7,8,13,17,29,30,32,34 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 109
- Ceres seq_id 1713896
- Location of start within SEQ ID NO 108: at 3 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 110
- Ceres seq_id 1713897
- Location of start within SEQ ID NO 108: at 57 nt . - Location of Signal Peptide Cleavage Site within SEQ
ID NO 110: at 20 aa .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 111 - Ceres seq_id 1713898
- Location of start within SEQ ID NO 108: at 81 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 111: at 17 aa. (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene. Maximum Length Sequence: related to: Clone IDs:
41879 (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 112 - Ceres seq_id 1923752
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 113 - Ceres seq_id 1923753
- Location of start within SEQ ID NO 112: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 113: at 19 aa. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 114
- Ceres seq_id 1923754
- Location of start within SEQ ID NO 112: at 292 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 115
- Ceres seq_id 1923755
- Location of start within SEQ ID NO 112: at 384 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 115: at 27 aa . (Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: related to: Clone IDs:
150069 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 116
- Ceres seq_id 1976816
- Alternative transcription start site(s) located in SEQ ID NO 116: 20,30,32
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 117
- Ceres seq_id 1976817 - Location of start within SEQ ID NO 116: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 117: at 61 aa.
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 118
- Ceres seq_id 1976818
- Location of start within SEQ ID NO 116: at 3 nt .
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 119
- Ceres seq_id 1976819
- Location of start within SEQ ID NO 116: at 52 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: related to: Clone IDs:
109997 Public Genomic DNA: gi No: 4263813 Predicted Exons:
INIT 82737 ... 82740 OCKHAMG-CDS TERM 83475 ... 83623 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 120 - Ceres seq__id 2025128 - Alternative transcription start site(s) located in SEQ ID NO 120:
-5,5,61,88
- Clone 109997 starts at 5 and ends at 566 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 121
- Ceres seq__id 2025129
- Location of start within SEQ ID NO 120: at 1 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 122
- Ceres seq_id 2025130
- Location of start within SEQ ID NO 120: at 3 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 122: at 21 aa .
Polypeptide Sequence
- Pat. Appln. SEQ ID NO 123
- Ceres seq_id 2025131
- Location of start within SEQ ID NO 120: at 316 nt ,
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length _ Sequence rela'ted to:
Clone IDs: 41792
Public Genomic I DNA: gi No: 5762549
Predicted Exons :
INTR 41272 . 41749 OCKHAMG-CDNA gi No: 5776585
Predicted Exons :
INTR 55175 . 55652 OCKHAMG-CDNA gi No: 5801669
Predicted Exons :
INTR 97802 . 98279 OCKHAMG-CDNA gi No: 5809709
Predicted Exons :
INTR 97803 . 98280 OCKHAMG-CDNA gi No: 5932531
Predicted Exons :
INTR 90652 . 91129 OCKHAMG-CDNA gi No: 6013612
Predicted Exons :
INTR 9143 . 9620 OCKHAMG-CDNA gi No: 6016671 Predicted Exons:
INTR 9266 ... 9743 OCKHAMG-CDNA gi No: 6041828 Predicted Exons:
INTR 9266 ... 9743 OCKHAMG-CDNA gi No: 6175159 Predicted Exons:
INTR 92644 ... 92167 OCKHAMG-CDNA
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 124
- Ceres seq_id 2025402
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 125
- Ceres seq_id 2025403
- Location of start within SEQ ID NO 124 at 186 nt,
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 126
- Ceres seq_id 2025404
- Location of start within SEQ ID NO 124: at 2 nt
(Ba) Polypeptide Activities: Similar to ribose 5- phosphate isomerase
Maximum Length Sequence related to:
Clone IDs:
28572
Public Genomic DNA: gi No: 4725940
Predicted Exons :
INIT 99197 . . 99167 OCKHAMG- -CDS
INTR 99060 . . 98960 OCKHAMG- -CDS
INTR 98863 . . 98753 OCKHAMG- -CDS
INTR 98654 . . 97823 OCKHAMG- -CDS
INTR 97730 . . 97477 OCKHAMG- -CDS
INTR 96772 . . 96683 OCKHAMG- -CDS
TERM 96157 . . 96086 OCKHAMG- -CDS gi No: 5823567
Predicted Exons :
INIT 99197 . . 99167 OCKHAMG- -CDS
INTR 99060 . . 98960 OCKHAMG- -CDS
INTR 98863 . . 98753 OCKHAMG- -CDS
INTR 98654 . . 97823 OCKHAMG- -CDS
INTR 97730 . . 97477 OCKHAMG- -CDS
INTR 96772 . . 96683 OCKHAMG- -CDS
TERM 96157 . . 96086 OCKHAMG- -CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 127
- Ceres seq_id 202. 5479 - Alternative transcription start site(s) located in SEQ ID NO 127:
1419
- Clone 28572 starts at 1419 and ends at 1955 in cDNA.
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 128
- Ceres seq_id 2025480
- Location of start within SEQ ID NO 127: at 1 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 129
- Ceres seq_id 2025481
- Location of start within SEQ ID NO 127: at 226 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 130
- Ceres seq_id 2025482
- Location of start within SEQ ID NO 127: at 271 nt .
(Ba) Polypeptide Activities: Similar Cell Wall Plasma Membrane disconnecting CLCT Protein activities, and proline rich protein activities.
Maximum Length Sequence: Public Genomic DNA: gi No: 6-34247
Predicted Exons:
INTR 46663 ... 46055 OCKHAMG-CDNA
SINGLE 46579 . 46103 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence - Pat. Appln. SEQ ID NO 131 - Ceres seq_id 2032963
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 132 - Ceres seq_id 2032964
- Location of start within SEQ ID NO 131: at 85 nt
Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: Public Genomic DNA: gi No: 6449509 Predicted Exons: INIT 32110 ... 32118 OCKHAMG-CDS
INTR 32363 ... 32538 OCKHAMG-CDS
INTR 33006 ... 33084 OCKHAMG-CDS
TERM 33182 ... 33247 OCKHAMG-CDS gi No: 6453848
Predicted Exons :
INIT 34795 ... 34803 OCKHAMG-CDS
INTR 35048 ... 35223 OCKHAMG-CDS
INTR 35691 ... 35769 OCKHAMG-CDS
TERM 35867 ... 35932 OCKHAMG-CDS gi No: 6456153
Predicted Exons :
INIT 32305 ... 32313 OCKHAMG-CDS
INTR 32558 ... 32733 OCKHAMG-CDS
INTR 33201 ... 33279 OCKHAMG-CDS
TERM 33377 ... 33442 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 133
- Ceres seq id 2033706
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 134
- Ceres seq_id 2033707
- Location of start within SEQ ID NO 133: at 1 nt .
[B) Polypeptide Sequence
- Dat. Appln. SEQ ID NO 135
- Ceres seq_id 2033708
- Location of start within SEQ ID NO 133: at 34 nt ,
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 136
- Ceres seq_id 2033709
- Location of start within SEQ ID NO 133: at 160 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence :
Public Genomic DNA: gi No: 4512646
Predictec 1 Exons:
INTR 43130 ... 43387 OCKHAMG-CDNA
INTR 43479 ... 43638 OCKHAMG-CDNA
INIT 43224 ... 43387 OCKHAMG-CDS
TERM 43479 ... 43494 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 137
- Ceres seq_id 2043118
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 138
- Ceres seq_id 2043119
- Location of start within SEQ ID NO 137: at 65 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 138: at 22 aa.
;B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 139
- Ceres seq_id 2043120
- Location of start within SEQ ID NO 137: at 1 nt . B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 140
- Ceres seq_id 2043121
- Location of start within SEQ ID NO 137 at 95 nt ,
[ Ba ) Polypeptide Activities Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: Public Genomic DNA: gi No: 3985934 Predicted Exons:
INTR 40094 .. 40516 OCKHAMG-CDNA INTR 40861 .. 41275 OCKHAMG-CDNA
INIT 40233 40516 OCKHAMG-CDS TERM 40861 41077 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 141
- Ceres seq_id 2047214
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 142
- Ceres seq_id 2047215
- Location of start within SEQ ID NO 141: at 140 nt
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 143
- Ceres seq_id 2047216
- Location of start within SEQ ID NO 141: at 224 nt ,
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 144
- Ceres seq_id 2047217
- Location of start within SEQ ID NO 141: at 153 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 144: at 18 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: Public Genomic DNA: gi No: 3985958 Predicted Exons: INTR 8598 8696 OCKHAMG-CDNA INTR 8960 ., 9035 OCKHAMG-CDNA INTR 9202 9513 OCKHAMG-CDNA INTR 9628 9669 OCKHAMG-CDNA
INIT 8997 9035 OCKHAMG-CDS INTR 9202 . , 9513 OCKHAMG-CDS TERM 9628 9822 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 145
- Ceres seq id 2047438
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 146
- Ceres seq_id 2047439
- Location of start within SEQ ID NO 145: at 137 nt ,
Maximum Length Sequence: Public Genomic DNA: gi No: 4757403 Predicted Exons: INTR 35281 .. 34781 OCKHAMG-CDNA
SINGLE 35235 ... 35005 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 147
- Ceres seq id 2049056
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 148
- Ceres seq_id 2049057
- Location of start within SEQ ID NO 147: at 47 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 148: at 22 aa. (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 149
- Ceres seq_id 2049058
- Location of start within SEQ ID NO 147: at 59 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 149: at 18 aa.
Maximum Length Sequence Public Genomic DNA: gi No: 4538972 Predicted Exons: INTR 32316 32561 OCKHAMG- -CDNA INTR 32643 32715 OCKHAMG- -CDNA INTR 33489 33697 OCKHAMG- -CDNA INTR 33789 33935 OCKHAMG- -CDNA INTR 34034 34365 OCKHAMG- -CDNA
INIT 32328 32561 OCKHAMG- -CDS INTR 32643 32715 OCKHAMG- -CDS INTR 33489 33697 OCKHAMG- -CDS INTR 33789 33935 OCKHAMG- -CDS TERM 34034 34159 OCKHAMG- -CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 150
- Ceres seq_id 2050386
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 151
- Ceres seq_id 2050387
- Location of start within SEQ ID NO 150: at 1 nt
[B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 152
- Ceres seq_id 2050388
- Location of start within SEQ ID NO 150: at 13 nt .
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 153
- Ceres seq_id 2050389
- Location of start within SEQ ID NO 150: at 151 nt ,
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
Maximum Length Sequence: Public Genomic DNA: gi No: 4878038 Predicted Exons:
INTR 22640 22509 OCKHAMG- -CDNA
INTR 22412 22340 OCKHAMG- -CDNA
INTR 22122 21728 OCKHAMG- -CDNA
INTR 22674 22509 OCKHAMG- -CDNA
INTR 22412 22340 OCKHAMG- -CDNA
INTR 22122 21766 OCKHAMG- -CDNA
INIT 22587 22509 OCKHAMG- -CDS
INTR 22412 22340 OCKHAMG- -CDS
TERM 22122 21852 OCKHAMG- -CDS gi No: 6143825
Predicted Exons
INTR 22639 22508 OCKHAMG- -CDNA
INTR 22411 22339 OCKHAMG- -CDNA
INTR 22121 21727 OCKHAMG- -CDNA
INTR 22673 22508 OCKHAMG- -CDNA
INTR 22411 22339 OCKHAMG- -CDNA
INTR 22121 21765 OCKHAMG- -CDNA
INIT 22586 22508 OCKHAMG-CDS
INTR 22411 22339 OCKHAMG-CDS
TERM 22121 21851 OCKHAMG-CDS
(Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 154
- Ceres seq_id 2053353
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 155
- Ceres seq_id 2053354
- Location of start within SEQ ID NO 154: at 88 nt
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene
Maximum Length Sequence: Public Genomic DNA: gi No: 4115352 Predicted Exons: INIT 29289 . . 29287 OCKHAMG- -CDS INTR 27681 . . 27485 OCKHAMG- -CDS INTR 27312 . . 27193 OCKHAMG- -CDS INTR 26979 . . 26916 OCKHAMG- -CDS TERM 26654 . . 26646 OCKHAMG- -CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 156
- Ceres seq_id 2055693 (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 157
- Ceres seq_id 2055694
- Location of start within SEQ ID NO 156: at 1 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 158
- Ceres seq_id 2055695
- Location of start within SEQ ID NO 156: at 46 nt . (B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 159
- Ceres seq_id 2055696
- Location of start within SEQ ID NO 156: at 2 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 159: at 28 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: Public Genomic DNA: gi No: 4406790
Predicted Exons:
INTR 81640 ... 81247 OCKHAMG-CDNA
SINGLE 81603 81367 OCKHAMG-CDS (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 160
- Ceres seq id 2056405
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 161
- Ceres seq_id 2056406
- Location of start within SEQ ID NO 160: at 38 nt
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 162
- Ceres seq_id 2056407
- Location of start within SEQ ID NO 160: at 56 nt
(B) Polypeptide Sequence
- Pat. Appln. SEQ ID NO 163 - Ceres seq_id 2056408
- Location of start within SEQ ID NO 160: at 177 nt .
- Location of Signal Peptide Cleavage Site within SEQ ID NO 163: at 14 aa.
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene,
Maximum Length Sequence: related to: Clone IDs:
233233 (Ac) cDNA Polynucleotide Sequence
- Pat. Appln. SEQ ID NO 164
- Ceres seq_id 2065747
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 165
- Ceres seq_id 2065748
- Location of start within SEQ ID NO 164: at 114 nt .
(B) Polypeptide Sequence - Pat. Appln. SEQ ID NO 166
- Ceres seq_id 2065749
- Location of start within SEQ ID NO 164: at 279 nt .
(Ba) Polypeptide Activities: Arabidopsis specific gene, dicot specific gene, plant specific gene.
SEQ TABLE 1
(2) INFORMATION FOR SEQ ID NO:l:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 601 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS : single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..601 (D) OTHER INFORMATION: / Ceres Seq ID 1007546
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:l: gacgaacagg ccacgcgtga ctacatacat aatttggttt ctcttttttt ttttgttctt 60 cttgttcctc tttggttttt gacattggtt ctggagaaga tgagttcggt agaaccagac 120 atggaagatc tgttccagga gaagaagcgt gtcaggaatc ctctcgttcc tctcggtgca 180 cttatgaccg cgggagtgct cacggctggg ttgattagtt tcagaagagg caattctcag 240 ttgggtcagg ttttgatgag agctagggtg gtcgtccagg gtgctactgt cgctttaatg 300 gttggaaccg gttattacta cggtgataat ccgtggaaga agtgagctcc aactacttgt 360 tcgttttcac ataattgaga tgacactcgg gaaacctgcg ggcaaaggtg tgtgtgctct 420 cgctctgagt gtagaaatat gcggtcttgc taggatttag taagggtaca ttacatgatt 480 tgaataattt gaagaacgaa caagtatcgt tgtatcttga tcaattgatt agattgattt 540 aaggaaattc tccgaaaacc atctttactc tatctgtcaa aatctcatta tctttctgcc 600 g
(2; INFORMATION FOR SEQ ID NO: 2:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 114 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..114 (D) OTHER INFORMATION: / Ceres Seq. ID 1007547
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:2: Asp Glu Gin Ala Thr Arg Asp Tyr lie His Asn Leu Val Ser Leu Phe 1 5 10 15
Phe Phe Val Leu Leu Val Pro Leu Trp Phe Leu Thr Leu Val Leu Glu
20 25 30
Lys Met Ser Ser Val Glu Pro Asp Met Glu Asp Leu Phe Gin Glu Lys
35 40 45
Lys Arg Val A.rg Asn Pro Leu Val Pro Leu Gly Ala Leu Met Thr Ala
50 55 60
Gly Val Leu Thr Ala Gly Leu lie Ser Phe Arg Arg Gly Asn Ser Gin 65 70 75 80
Leu Gly Gin Val Leu Met Arg Ala Arg Val Val Val Gin Gly Ala Thr
85 90 95
Val Ala Leu Met Val Gly Thr Gly Tyr Tyr Tyr Gly Asp Asn Pro Trp
100 105 110
Lys Lys
(2) INFORMATION FOR SEQ ID NO: 3:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 81 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..81 (D) OTHER INFORMATION: / Ceres Seq. ID 1007548 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 3: Met Ser Ser Val Glu Pro Asp Met Glu Asp Leu Phe Gin Glu Lys Lys 1 5 10 15
Arg Val Arg Asn Pro Leu Val Pro Leu Gly Ala Leu Met Thr Ala Gly
20 25 30
Val Leu Thr Ala Gly Leu lie Ser Phe Arg Arg Gly Asn Ser Gin Leu
35 40 45
Gly Gin Val Leu Met Arg Ala Arg Val Val Val Gin Gly Ala Thr Val
50 55 60
Ala Leu Met Val Gly Thr Gly Tyr Tyr Tyr Gly Asp Asn Pro Trp Lys 65 70 75 80
Lys
(2) INFORMATION FOR SEQ ID NO: 4:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 1007549 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 4: Met Glu Asp Leu Phe Gin Glu Lys Lys Arg Val Arg Asn Pro Leu Val 1 5 10 15
Pro Leu Gly Ala Leu Met Thr Ala Gly Val Leu Thr Ala Gly Leu He
20 25 30
Ser Phe Arg Arg Gly Asn Ser Gin Leu Gly Gin Val Leu Met Arg Ala
35 40 45
Arg Val Val Val Gin Gly Ala Thr Val Ala Leu Met Val Gly Thr Gly
50 55 60
Tyr Tyr Tyr Gly Asp Asn Pro Trp Lys Lys 65 70
(2) INFORMATION FOR SEQ ID NO: 5:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 970 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..970 (D) OTHER INFORMATION: / Ceres Seq. ID 10075 83 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 5: aacgccgctc atttttaggg tttcagatat aggcagattc tcacatttgc aaacatgacg 60 actcagatca gcaagaagag aaagtttgta gcggacggtg tgttctacgc tgaattgaat 120 gaggttctta caagagagct agcagaggat ggttactctg gtgttgaggt tagggttact 180 cctatgagga ctgagattat catcagagct acacgtactc agaatgttct cggtgagaag 240 gggaggagaa ttagggaatt gacttccctt gttcagaaga gattcaagtt tccagttgac 300 agtgttgagc tttatgccga gaaggttaac aacagaggtc tctgtgccat cgctcaggct 360 gagtctttac gttacaagct tcttggtggt ctcgctgttc gtagggcttg ctatggtgtg 420 ttgaggtttg ttatggagag tggagctaag ggatgcgagg ttatcgtgag tggaaagctt 480 cgtgctgcca gagccaagtc tatgaagttc aaagatggct acatggtgtc atctggtcaa 540 ccaactaagg aatacataga ctctgcagtg agacatgttt tgcttagaca aggtgtgttg 600 ggaatcaagg tgaaggttat gcttgattgg gaccctaagg gcatatcagg accaaagaca 660 ccattgcctg atgttgtgat cattcattct cctaaagaag aagaggccat ctacgcacct 720 gctcaggttg ctgccccggc tgctctcgta gcagatgcac cactcacagc cgtagattac 780 cctgcgatga tcccagtcgc ctaaaagaat cctttgtact agtcgatgtg attttgtttt 840 caactgttct tgctcttttg acagattata gcttctcgta tcttcgaatc agacacgttt 900 cctctgttct tattcgaaaa ttatctcaag tttccattgt tgaaaaagcc ctttttagtt 960 tcataaatcg
(2) INFORMATION FOR SEQ ID NO: 6: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 249 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..249
(D) OTHER INFORMATION: / Ceres Seq. ID 1007584 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 6:
Met Thr Thr Gin He Ser Lys Lys Arg Lys Phe Val Ala Asp Gly Val 1 5 10 15
Phe Tyr Ala Glu Leu Asn Glu Val Leu Thr Arg Glu Leu Ala Glu Asp 20 25 30 Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He 35 40 45
He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg
50 55 60
Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys Arg Phe Lys Phe Pro 65 70 75 80
Val Asp Ser Val Glu Leu Tyr Ala Glu Lys Val Asn Asn Arg Gly Leu
85 90 95
Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly 100 105 110 Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu 115 120 125
Ser Gly Ala Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala
130 135 140
Ala Arg Ala Lys Ser Met Lys Phe Lys Asp Gly Tyr Met Val Ser Ser 145 150 155 160
Gly Gin Pro Thr Lys Glu Tyr He Asp Ser Ala Val Arg His Val Leu
165 170 175
Leu Arg Gin Gly Val Leu Gly He Lys Val Lys Val Met Leu Asp Trp 180 185 190 Asp Pro Lys Gly He Ser Gly Pro Lys Thr Pro Leu Pro Asp Val Val 195 200 205
He He His Ser Pro Lys Glu Glu Glu Ala He Tyr Ala Pro Ala Gin
210 215 220
Val Ala Ala Pro Ala Ala Leu Val Ala Asp Ala Pro Leu Thr Ala Val 225 230 235 240
Asp Tyr Pro Ala Met He Pro Val Ala
245 (2) INFORMATION FOR SEQ ID NO: 7:
(i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 206 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..206
(D) OTHER INFORMATION: / Ceres Seq. ID 1007585 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 7: Met Arg Thr Glu He He He Arg Ala Thr Arg Thr Gin Asn Val Leu 1 5 10 15
Gly Glu Lys Gly Arg Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys 20 25 30
Arg Phe Lys Phe Pro Val Asp Ser Val Glu Leu Tyr Ala Glu Lys Val
35 40 45
Asn Asn Arg Gly Leu Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr
50 55 60
Lys Leu Leu Gly Gly Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu 65 70 75 80
Arg Phe Val Met Glu Ser Gly Ala Lys Gly Cys Glu Val He Val Ser
85 90 95
Gly Lys Leu Arg Ala Ala Arg Ala Lys Ser Met Lys Phe Lys Asp Gly 100 105 110
Tyr Met Val Ser Ser Gly Gin Pro Thr Lys Glu Tyr He Asp Ser Ala
115 120 125
Val Arg His Val Leu Leu Arg Gin Gly Val Leu Gly He Lys Val Lys
130 135 140
Val Met Leu Asp Trp Asp Pro Lys Gly He Ser Gly Pro Lys Thr Pro 145 150 155 160
Leu Pro Asp Val Val He He His Ser Pro Lys Glu Glu Glu Ala He
165 170 175
Tyr Ala Pro Ala Gin Val Ala Ala Pro Ala Ala Leu Val Ala Asp Ala 180 185 190
Pro Leu Thr Ala Val Asp Tyr Pro Ala Met He Pro Val Ala
195 200 205
(2) INFORMATION FOR SEQ ID NO: 8:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 768 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..768
(D) OTHER INFORMATION: / Ceres Seq. ID 100814 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 8: aaaaaaaccc tagttttttg ctctctcgaa gttccgtgcg actctctgct cgagcaagat 60 ctcctaccga tacaatgatt atctcagagg ctaaccgcaa agaaatctgc aagtacctct 120 tcaaagaagg agtttgcttt gcgaagaagg atttcaatct tgctaagcat ccgttgatcg 180 atgtcccgaa cctacaagtg attaagctta tgcagagttt caaatccaag gagtatgtta 240 gagagacatt tgcctggatg cattactatt ggtttttgac caatgaaggg atcgagttct 300 tgagaactta tcttaatctt ccatctgatg ttgttcctgc tactttgaag aagtcagcta 360 agcctggtgg tcgtccattt ggtggcccac ctggtgatcg ctcaagagga cctcgccatg 420 aaggaggaga ccgtcccagg tttggtgacc gtgatgggta ccgtgcaggt cctcgagctg 480 gtggtgagtt tggaggtgaa aagggtggag ctcctgcaga ttaccagcca tctttccaag 540 gaagtgggcg tggttttggc cgtggtgctg gtggctacag cgcagctgca ccatctggtt 600 caggtttgcc ttgaaaaaga aatgtcttta ggtgacagta agaccatgga ggagttttca 660 gctttaaatt ttgcttttgt aattcagatt ccggaatcct tcataatctc tatctgagtt 720 tagttttgtt gttgaatcaa acatccgatt taaagttatg ttcattcc (2) INFORMATION FOR SEQ ID NO: 9:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 203 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..203
(D) OTHER INFORMATION: / Ceres Seq. ID 1008149
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 9:
Lys Asn Pro Ser Phe Leu Leu Ser Arg Ser Ser Val Arg Leu Ser Ala
10 15 Arg Ala Arg Ser Pro Thr Asp Thr Met He He Ser Glu Ala Asn Arg
20 25 30
Lys Glu He Cys Lys Tyr Leu Phe Lys Glu Gly Val Cys Phe Ala Lys 35 40 45 Lys Asp Phe Asn Leu Ala Lys His Pro Leu He Asp Val Pro Asn Leu 50 55 60
Gin Val He Lys Leu Met Gin Ser Phe Lys Ser Lys Glu Tyr Val Arg 65 70 75 80
Glu Thr Phe Ala Trp Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly 85 90 95
He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro Ser Asp Val Val Pro
100 105 110
Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly Gly 115 120 125 Pro Pro Gly Asp Arg Ser Arg Gly Pro Arg His Glu Gly Gly Asp Arg 130 135 140
Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg Ala Gly Pro Arg Ala Gly 145 150 155 160
Gly Glu Phe Gly Gly Glu Lys Gly Gly Ala Pro Ala Asp Tyr Gin Pro 165 170 175
Ser Phe Gin Gly Ser Gly Arg Gly Phe Gly Arg Gly Ala Gly Gly Tyr
180 185 190
Ser Ala Ala Ala Pro Ser Gly Ser Gly Leu Pro 195 200 (2) INFORMATION FOR SEQ ID NO:10: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 179 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..179 (D) OTHER INFORMATION: / Ceres Seq. ID 1008150
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 10: Met He He Ser Glu Ala Asn Arg Lys Glu He Cys Lys Tyr Leu Phe 1 5 10 15
Lys Glu Gly Val Cys Phe Ala Lys Lys Asp Phe Asn Leu Ala Lys His 20 25 30
Pro Leu He Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser
35 40 45
Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His Tyr 50 55 60 Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu 65 70 75 80
Asn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys
85 90 95
Pro Gly Gly Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg Ser Arg Gly 100 105 110
Pro Arg His Glu Gly Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly
115 120 125
Tyr Arg Ala Gly Pro Arg Ala Gly Gly Glu Phe Gly Gly Glu Lys Gly
130 135 140 Gly Ala Pro Ala Asp Tyr Gin Pro Ser Phe Gin Gly Ser Gly Arg Gly
145 150 155 160
Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser
165 170 175
Gly Leu Pro
(2) INFORMATION FOR SEQ ID NO: 11: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 134 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..134
(D) OTHER INFORMATION: / Ceres Seq. ID 1008151
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 11: Met Gin Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp 1 5 10 15
Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg
20 25 30
Thr Tyr Leu Asn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys
35 40 45
Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg
50 55 60
Ser Arg Gly Pro Arg His Glu Gly Gly Asp Arg Pro Arg Phe Gly Asp 65 70 75 80
Arg Asp Gly Tyr Arg Ala Gly Pro Arg Ala Gly Gly Glu Phe Gly Gly
85 90 95
Glu Lys Gly Gly Ala Pro Ala Asp Tyr Gin Pro Ser Phe Gin Gly Ser
100 105 110
Gly Arg Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro
115 120 125
Ser Gly Ser Gly Leu Pro
130 (2) INFORMATION FOR SEQ ID NO: 12: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 995 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..995
(D) OTHER INFORMATION: / Ceres Seq. ID 1008334 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 12: atatctaaaa gactcaaaaa cctatcgtca tttatcttca acaggcggaa gaacggcgat 60 ggccgccatt acagctctca ctctccgctc tcctgttttt cttcttcctc catcgtccgt 120 cacaagccct agattccatg gcttcaccaa tcaaccacca ccagctcgtc tcttctttcc 180 tcttaacccc ttcccttctc tatcaatcca aaaccctaaa tccatccgaa tttccgcatc 240 cgcttcgccg ataacaacac caatcctcca gacggagaag tcaacagctc ggtcatcgac 300 actcaccggg tccactcggt ctctcgctac tctcgcggct ttagcaatcg ctgtaaccag 360 agtcctagct cagaaactct ctctcgcaat ccagacttca agtcccgtaa tcgccgacgg 420 gttacgattc tctctcagta ccgccggacc tgtcttcttc gcgtctctcc gggatcgtcc 480 tccgggatac ttgaacacgc cgctgacggt tgttgcggtg gggataaaga agtggctaga 540 catttacagt ggggtattga tggttagggt tttgctgagt tggttcccta atatcccttg 600 ggaaagacag cctttgtctg ccattagaga tctctgtgat ccttacttga atctcttcag 660 aaacatcatt cctcctatct tcgatacgct tgatgttagt ccattgcttg ctttcgcggt 720 tcttggtaca cttggatcga ttgttcatgg cagcactggg tagaaattgg aagacttgag 780 ctaatggttt tgttgaaacg ttcaattggg aaatttctgc aacttgtttc ccaagattag 840 ggaaaaatca gaatttgatg ctgtgttgga tgctcgatga gagttgtgag ctttatcgtt 900 tttgttgttc tctttttgac tttgattctg aataatgaga ttttgggttg ttgtttatct 960 cctaattaca tgttcagact acagtttatt gatgg (2) INFORMATION FOR SEQ ID NO: 13: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 253 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..253
(D) OTHER INFORMATION: / Ceres Seq. ID 1008335 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 13: Tyr Leu Lys Asp Ser Lys Thr Tyr Arg His Leu Ser Ser Thr Gly Gly 1 5 10 15 Arg Thr Ala Met Ala Ala He Thr Ala Leu Thr Leu Arg Ser Pro Val 20 25 30
Phe Leu Leu Pro Pro Ser Ser Val Thr Ser Pro Arg Phe His Gly Phe
35 40 45
Thr Asn Gin Pro Pro Pro Ala Arg Leu Phe Phe Pro Leu Asn Pro Phe 50 55 60
Pro Ser Leu Ser He Gin Asn Pro Lys Ser He Arg He Ser Ala Ser 65 70 75 80
Ala Ser Pro He Thr Thr Pro He Leu Gin Thr Glu Lys Ser Thr Ala 85 90 95 Arg Ser Ser Thr Leu Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu Ala
100 105 110
Ala Leu Ala He Ala Val Thr Arg Val Leu Ala Gin Lys Leu Ser Leu
115 120 125
Ala He Gin Thr Ser Ser Pro Val He Ala Asp Gly Leu Arg Phe Ser 130 135 140
Leu Ser Thr Ala Gly Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro
145 150 155 160
Pro Gly Tyr Leu Asn Thr Pro Leu Thr Val Val Ala Val Gly He Lys
165 170 175 Lys Trp Leu Asp He Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu
180 185 190
Ser Trp Phe Pro Asn He Pro Trp Glu Arg Gin Pro Leu Ser Ala He
195 200 205
Arg Asp Leu Cys Asp Pro Tyr Leu Asn Leu Phe Arg Asn He He Pro 210 215 220
Pro He Phe Asp Thr Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val 225 230 235 240
Leu Gly Thr Leu Gly Ser He Val His Gly Ser Thr Gly 245 250 (2) INFORMATION FOR SEQ ID NO: 14: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 234 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..234 (D) OTHER INFORMATION: / Ceres Seq. ID 1008336
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 14: Met Ala Ala He Thr Ala Leu Thr Leu Arg Ser Pro Val Phe Leu Leu 1 5 10 15
Pro Pro Ser Ser Val Thr Ser Pro Arg Phe His Gly Phe Thr Asn Gin 20 25 30
Pro Pro Pro Ala Arg Leu Phe Phe Pro Leu Asn Pro Phe Pro Ser Leu
35 40 45
Ser He Gin Asn Pro Lys Ser He Arg He Ser Ala Ser Ala Ser Pro 50 55 60 He Thr Thr Pro He Leu Gin Thr Glu Lys Ser Thr Ala Arg Ser Ser 65 70 75 80
Thr Leu Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu Ala Ala Leu Ala 85 90 95
He Ala Val Thr Arg Val Leu Ala Gin Lys Leu Ser Leu Ala He Gin 100 105 110
Thr Ser Ser Pro Val He Ala Asp Gly Leu Arg Phe Ser Leu Ser Thr 115 120 125
Ala Gly Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro Pro Gly Tyr
130 135 140
Leu Asn Thr Pro Leu Thr Val Val Ala Val Gly He Lys Lys Trp Leu
145 150 155 160
Asp He Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu Ser Trp Phe 165 170 175
Pro Asn He Pro Trp Glu Arg Gin Pro Leu Ser Ala He Arg Asp Leu 180 185 190
Cys Asp Pro Tyr Leu Asn Leu Phe Arg Asn He He Pro Pro He Phe 195 200 205
Asp Thr Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val Leu Gly Thr 210 215 220
Leu Gly Ser He Val His Gly Ser Thr Gly
225 230
( 2 ) INFORMATION FOR SEQ ID NO : 15 :
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 520 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..520 (D) OTHER INFORMATION: / Ceres Seq. ID 1008701
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 15: acacataacc ctcttggaaa gagtctcaac acttgcagag aaaaagaaga aggaagatcc 60 cggaaaatgg caacggcgat tgtacgttca gctctttccc gagcagcgac tcgcgcagct 120 ccgaagacat ccgtcgctcc taagcgaaac ttttcctctt ccgccggcca tgacgatgct 180 tatgaagctg cgaagtggga gaagataact tatctgggta ttgctagttg cactgctcta 240 gctgtctatg ttttatccaa gggccatcat cccggcgaag accctcctgc ctatccgcat 300 atgcacatcc gcaacaagga gtttccttgg ggtccggatg gtctgtttga ggtgaagcac 360 aacaaagagc actgagtctt gcgtggtcat aataacgtct tcttggttta tttgaaaggc 420 taaaatgttt taccgtattt gttctcaccg tttgtcaacg attttctact ccaatctctt 480 ttcttttgtt gggaaataaa agttaatact ttgcttggtc (2) INFORMATION FOR SEQ ID NO: 16: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 124 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..124
(D) OTHER INFORMATION: / Ceres Seq. ID 1008702 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 16: Thr His Asn Pro Leu Gly Lys Ser Leu Asn Thr Cys Arg Glu Lys Glu 1 5 10 15
Glu Gly Arg Ser Arg Lys Met Ala Thr Ala He Val Arg Ser Ala Leu
20 25 30
Ser Arg Ala Ala Thr Arg Ala Ala Pro Lys Thr Ser Val Ala Pro Lys
35 40 45
Arg Asn Phe Ser Ser Ser Ala Gly His Asp Asp Ala Tyr Glu Ala Ala
50 55 60
Lys Trp Glu Lys He Thr Tyr Leu Gly He Ala Ser Cys Thr Ala Leu 65 70 75 80 Ala Val Tyr Val Leu Ser Lys Gly His His Pro Gly Glu Asp Pro Pro
85 90 95
Ala Tyr Pro His Met His He Arg Asn Lys Glu Phe Pro Trp Gly Pro 100 105 110 Asp Gly Leu Phe Glu Val Lys His Asn Lys Glu His 115 120
(2) INFORMATION FOR SEQ LD NO: 17: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..102
(D) OTHER INFORMATION: / Ceres Seq. ID 1008703 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 17: Met Ala Thr Ala He Val Arg Ser Ala Leu Ser Arg Ala Ala Thr Arg 1 5 10 15
Ala Ala Pro Lys Thr Ser Val Ala Pro Lys Arg Asn Phe Ser Ser Ser
20 25 30
Ala Gly His Asp Asp Ala Tyr Glu Ala Ala Lys Trp Glu Lys He Thr 35 40 45 Tyr Leu Gly He Ala Ser Cys Thr Ala Leu Ala Val Tyr Val Leu Ser 50 55 60
Lys Gly His His Pro Gly Glu Asp Pro Pro Ala Tyr Pro His Met His 65 70 75 80
He Arg Asn Lys Glu Phe Pro Trp Gly Pro Asp Gly Leu Phe Glu Val 85 90 95
Lys His Asn Lys Glu His
100 (2) INFORMATION FOR SEQ ID NO: 18: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 68 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..68
(D) OTHER INFORMATION: / Ceres Seq. ID 1008704 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 18: His He Thr Leu Leu Glu Arg Val Ser Thr Leu Ala Glu Lys Lys Lys 1 5 10 15
Lys Glu Asp Pro Gly Lys Trp Gin Arg Arg Leu Tyr Val Gin Leu Phe
20 25 30
Pro Glu Gin Arg Leu Ala Gin Leu Arg Arg His Pro Ser Leu Leu Ser 35 40 45
Glu Thr Phe Pro Leu Pro Pro Ala Met Thr Met Leu Met Lys Leu Arg
50 55 60
Ser Gly Arg A.rg 65 (2) INFORMATION FOR SEQ ID NO: 19: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 662 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY : -
(B) LOCATION: 1..662 (D) OTHER INFORMATION: / Ceres Seq. ID 1009003
(xi ; SEQUENCE DESCRIPTION: SEQ ID NO: 19: cattttttct ttctctctct cctccctaag caaaactaaa acaagctatg gctggtatgc 60 ttcccggagt tgagtgtgca aggaggcggc gcttccacgg tggtgctcct ccgattgaat 120 cctcgaacac agcttctgtg gcggctgcgg cgggacacgt ctggacacgg cgaccatcgt 180 tctctcttta cactaccaat catgagagcc accaggccca tgtctccttc tcggagagaa 240 gtgttaggaa taaatcttat ggagaagaca acgatgagaa acttgacgga gcagccaaag 300 aggcaaagca gaggcttaac aagcggctga gaatcccacc acgtacaagt tcaggcaaaa 360 tggtaaagac aaagggaata aattggagca aggaaagggt aaacctctcg gggacttacc 420 gaccgaggtg gtcgggttaa agaagagccg aggaaggttg atggaatggt tcaagcggcg 480 agttagggaa caacaagatt gtgctatatg tctagaccgg ttcaagaagg gtgagacctt 540 ggtacaccta ccatgtgccc ataagtttca ctccatatgc ttattgcctt ggctagacac 600 taatgtttat tgcccatatt gtagaactga tatttggaat taaatgttat atttttgatg 660 cc
(2) INFORMATION FOR SEQ ID NO: 20:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 130 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..130 (D) OTHER INFORMATION: / Ceres Seq. ID 1009004
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 20: Met Ala Gly Met Leu Pro Gly Val Glu Cys Ala Arg Arg Arg Arg Phe 1 5 10 15
His Gly Gly Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala
20 25 30
Ala Ala Ala Gly His Val Trp Thr Arg Arg Pro Ser Phe Ser Leu Tyr
35 40 45
Thr Thr Asn His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg
50 55 60
Ser Val Arg Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp 65 70 75 80
Gly Ala Ala Lys Glu Ala Lys Gin Arg Leu Asn Lys Arg Leu Arg He
85 90 95
Pro Pro Arg Thr Ser Ser Gly Lys Met Val Lys Thr Lys Gly He Asn
100 105 110
Trp Ser Lys Glu Arg Val Asn Leu Ser Gly Thr Tyr Arg Pro Arg Trp
115 120 125
Ser Gly 130
(2) INFORMATION FOR SEQ ID NO: 21: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 127 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..127
(D) OTHER INFORMATION: / Ceres Seq. ID 1009005 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 21: Met Leu Pro Gly Val Glu Cys Ala Arg Arg Arg Arg Phe His Gly Gly 1 5 10 15
Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala Ala Ala Ala 20 25 30 Gly His Val Trp Thr Arg Arg Pro Ser Phe Ser Leu Tyr Thr Thr Asn
35 40 45
His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg Ser Val Arg 50 55 60 Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp Gly Ala Ala 65 70 75 80
Lys Glu Ala Lys Gin Arg Leu Asn Lys Arg Leu Arg He Pro Pro Arg
85 90 95
Thr Ser Ser Gly Lys Met Val Lys Thr Lys Gly He Asn Trp Ser Lys 100 105 110
Glu Arg Val Asn Leu Ser Gly Thr Tyr Arg Pro Arg Trp Ser Gly
115 120 125
(2) INFORMATION FOR SEQ ID NO: 22: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 504 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..504
(D) OTHER INFORMATION: / Ceres Seq. ID 1009345 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:22: aagaaacaaa ggtgtcaaga agaaggatca acatattaat tgactaaaaa tgaatgcatg 60 gatgataatc ttgttggtga tttgtgtcgc tgtggtggtg gagcaatcag aggctcgcaa 120 aggtcgaaag tatttaaatc caggcgtgct tgaccggtgt cgtggtccta atcctccagc 180 gggatgtcat cctcacaatt cccaccacaa acctcgcgtc cctgttcaca attatagtcg 240 tggttgtagt agaattaccc ggtgcagacg agatgcctag gtttaacctc acatgacgac 300 gacgtccctt tatattgatc cttcttctac atgagacttg caatgatatt atatattcat 360 atatatacac attacgctgt atatgataat tccagttgat taatatataa atcttactga 420 tttcaattca atacacaaga tcctgtaact gaaataattt tgtccatgtt ttgtgcttat 480 aataatggta tgactcttat tatt (2) INFORMATION FOR SEQ ID NO: 23: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 76 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..76
(D) OTHER INFORMATION: / Ceres Seq. ID 1009346 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:23:
Met Asn Ala Trp Met He He Leu Leu Val He Cys Val Ala Val Val 1 5 10 15
Val Glu Gin Ser Glu Ala Arg Lys Gly Arg Lys Tyr Leu Asn Pro Gly 20 25 30 Val Leu Asp Arg Cys Arg Gly Pro Asn Pro Pro Ala Gly Cys His Pro 35 40 45
His Asn Ser His His Lys Pro Arg Val Pro Val His Asn Tyr Ser Arg
50 55 60
Gly Cys Ser Arg He Thr Arg Cys Arg Arg Asp Ala 65 70 75
(2) INFORMATION FOR SEQ ID NO: 24: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 72 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..72
(D) OTHER INFORMATION: / Ceres Seq. ID 1009347 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:24: Met He He Leu Leu Val He Cys Val Ala Val Val Val Glu Gin Ser 1 5 10 15
Glu Ala A_rg Lys Gly Arg Lys Tyr Leu Asn Pro Gly Val Leu Asp Arg
20 25 30
Cys Arg Gly Pro Asn Pro Pro Ala Gly Cys His Pro His Asn Ser His
35 40 45
His Lys Pro Arg Val Pro Val His Asn Tyr Ser Arg Gly Cys Ser Arg
50 55 60
He Thr Arg Cys Arg Arg Asp Ala
65 70
(2) INFORMATION FOR SEQ ID NO: 25:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 967 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..967 (D) OTHER INFORMATION: / Ceres Seq. ID 1010140
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 25: attttatttc ttctccaacc attctcaatc ctctctctcc aatggcttcc ttatccttcg 60 tttcctcttc tcaccttacg ctacgcactc cttctattgc cctacgcagc actggctctt 120 ctcctcgaac ctccgtttca ttctccgtca aggctcaatc cgtcgcgctt tcacaggacg 180 atttgaagaa gctcgcggcg gagaaagctg tggaggcaat taaacctggg atggttctag 240 ggctcggaac cggatccacc gcagctttcg ctgttgatca gatcgggaaa ctactctctt 300 ccggtgaact ctacgatatt gtcggtatcc caacgtcgaa acgaacggag gaacaagcac 360 ggtcgttagg gattcctctt gttgggttag atacacatcc gagaatcgat ctcgctattg 420 acggagcaga cgaggtagat ccgaatcttg atttagtcaa aggtcgtgga ggtgctcttc 480 tccgtgagaa aatggtggaa gctgtggctg acaagtttat tgttgtggct gatgatacca 540 aactcgttac aggactcggt ggaagtggat tagctatgcc ggtggaagtt gttcaattct 600 gctggaactt taatttgatt agattgcaag agctcttcaa ggaatttgga tgtgaatcaa 660 agcttagagt tgatggtgat ggcaagcctt atgtgactga taacagtaat tacattattg 720 atttgtattt taagactcct ttgaaggatg gattcgctgc ggctaaagag attgggaagt 780 ttcaaggagt ggtggagcat ggtctgtttc tcggaatggc tacttctgtc attatcgctg 840 gaaagaatgg cgttgaagtt atgaccaagt gaggttaaaa gttcaatctt tctcttcttc 900 tttgattgac aaatttttct cctttgtaaa attatcaatt gagtttttat gtgagatcat 960 ttcaatc (2) INFORMATION FOR SEQ ID NO: 26:
;i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 289 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..289
(D) OTHER INFORMATION: / Ceres Seq. ID 1010141 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:26: Phe He Ser Ser Pro Thr He Leu Asn Pro Leu Ser Pro Met Ala Ser 1 5 10 15
Leu Ser Phe Val Ser Ser Ser His Leu Thr Leu Arg Thr Pro Ser He
20 25 30
Ala Leu Arg Ser Thr Gly Ser Ser Pro Arg Thr Ser Val Ser Phe Ser 35 40 45 Val Lys Ala Gin Ser Val Ala Leu Ser Gin Asp Asp Leu Lys Lys Leu
50 55 60
Ala Ala Glu Lys Ala Val Glu Ala He Lys Pro Gly Met Val Leu Gly 65 70 75 80 Leu Gly Thr Gly Ser Thr Ala Ala Phe Ala Val Asp Gin He Gly Lys
85 90 95
Leu Leu Ser Ser Gly Glu Leu Tyr Asp He Val Gly He Pro Thr Ser
100 105 110
Lys Arg Thr Glu Glu Gin Ala Arg Ser Leu Gly He Pro Leu Val Gly 115 120 125
Leu Asp Thr His Pro Arg He Asp Leu Ala He Asp Gly Ala Asp Glu
130 135 140
Val Asp Pro Asn Leu Asp Leu Val Lys Gly Arg Gly Gly Ala Leu Leu 145 150 155 160 Arg Glu Lys Met Val Glu Ala Val Ala Asp Lys Phe He Val Val Ala
165 170 175
Asp Asp Thr Lys Leu Val Thr Gly Leu Gly Gly Ser Gly Leu Ala Met
180 185 190
Pro Val Glu Val Val Gin Phe Cys Trp Asn Phe Asn Leu He Arg Leu 195 200 205
Gin Glu Leu Phe Lys Glu Phe Gly Cys Glu Ser Lys Leu Arg Val Asp
210 215 220
Gly Asp Gly Lys Pro Tyr Val Thr Asp Asn Ser Asn Tyr He He Asp 225 230 235 240 Leu Tyr Phe Lys Thr Pro Leu Lys Asp Gly Phe Ala Ala Ala Lys Glu
245 250 255
He Gly Lys Phe Gin Gly Val Val Glu His Gly Leu Phe Leu Gly Met
260 265 270
Ala Thr Ser Val He He Ala Gly Lys Asn Gly Val Glu Val Met Thr 275 280 285
Lys
(2) INFORMATION FOR SEQ ID NO: 27: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 276 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..276
(D) OTHER INFORMATION: / Ceres Seq. ID 1010142 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:27: Met Ala Ser Leu Ser Phe Val Ser Ser Ser His Leu Thr Leu Arg Thr 1 5 10 15
Pro Ser He Ala Leu Arg Ser Thr Gly Ser Ser Pro Arg Thr Ser Val
20 25 30
Ser Phe Ser Val Lys Ala Gin Ser Val Ala Leu Ser Gin Asp Asp Leu 35 40 45
Lys Lys Leu Ala Ala Glu Lys Ala Val Glu Ala He Lys Pro Gly Met
50 55 60
Val Leu Gly Leu Gly Thr Gly Ser Thr Ala Ala Phe Ala Val Asp Gin 65 70 75 80 He Gly Lys Leu Leu Ser Ser Gly Glu Leu Tyr Asp He Val Gly He
85 90 95
Pro Thr Ser Lys Arg Thr Glu Glu Gin Ala Arg Ser Leu Gly He Pro
100 105 110
Leu Val Gly Leu Asp Thr His Pro Arg He Asp Leu Ala He Asp Gly 115 120 125
Ala Asp Glu Val Asp Pro Asn Leu Asp Leu Val Lys Gly Arg Gly Gly 130 135 140 Ala Leu Leu Arg Glu Lys Met Val Glu Ala Val Ala Asp Lys Phe He 145 150 155 160
Val Val Ala Asp Asp Thr Lys Leu Val Thr Gly Leu Gly Gly Ser Gly 165 170 175 Leu Ala Met Pro Val Glu Val Val Gin Phe Cys Trp Asn Phe Asn Leu 180 185 190
He Arg Leu Gin Glu Leu Phe Lys Glu Phe Gly Cys Glu Ser Lys Leu
195 200 205
Arg Val Asp Gly Asp Gly Lys Pro Tyr Val Thr Asp Asn Ser Asn Tyr 210 215 220
He He Asp Leu Tyr Phe Lys Thr Pro Leu Lys Asp Gly Phe Ala Ala 225 230 235 240
Ala Lys Glu He Gly Lys Phe Gin Gly Val Val Glu His Gly Leu Phe 245 250 255 Leu Gly Met Ala Thr Ser Val He He Ala Gly Lys Asn Gly Val Glu 260 265 270
Val Met Thr Lys
275 (2) INFORMATION FOR SEQ ID NO: 28: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 213 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..213
(D) OTHER INFORMATION: / Ceres Seq. ID 1010143 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 28:
Met Val Leu Gly Leu Gly Thr Gly Ser Thr Ala Ala Phe Ala Val Asp 1 5 10 15
Gin He Gly Lys Leu Leu Ser Ser Gly Glu Leu Tyr Asp He Val Gly 20 25 30 He Pro Thr Ser Lys Arg Thr Glu Glu Gin Ala Arg Ser Leu Gly He 35 40 45
Pro Leu Val Gly Leu Asp Thr His Pro Arg He Asp Leu Ala He Asp
50 55 60
Gly Ala Asp Glu Val Asp Pro Asn Leu Asp Leu Val Lys Gly Arg Gly 65 70 75 80
Gly Ala Leu Leu Arg Glu Lys Met Val Glu Ala Val Ala Asp Lys Phe
85 90 95
He Val Val Ala Asp Asp Thr Lys Leu Val Thr Gly Leu Gly Gly Ser 100 105 110 Gly Leu Ala Met Pro Val Glu Val Val Gin Phe Cys Trp Asn Phe Asn 115 120 125
Leu He Arg Leu Gin Glu Leu Phe Lys Glu Phe Gly Cys Glu Ser Lys
130 135 140
Leu Arg Val Asp Gly Asp Gly Lys Pro Tyr Val Thr Asp Asn Ser Asn 145 150 155 160
Tyr He He Asp Leu Tyr Phe Lys Thr Pro Leu Lys Asp Gly Phe Ala
165 170 175
Ala Ala Lys Glu He Gly Lys Phe Gin Gly Val Val Glu His Gly Leu 180 185 190 Phe Leu Gly Met Ala Thr Ser Val He He Ala Gly Lys Asn Gly Val 195 200 205
Glu Val Met Thr Lys
210 (2) INFORMATION FOR SEQ ID NO: 29: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 623 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..623 (D) OTHER INFORMATION: / Ceres Seq. ID 1010217 xi SEQUENCE DESCRIPTION: SEQ ID NO:29: gaaaaccctt aagctaagca aatttcaaag caattcaaaa accctagcct ctctctcttt 60 atctctcaca acaaaatctt tgaaatggcg atctctaagg cttccattgt tgttctcatg 120 atggtgatta tctccgtcgt tgcatcggca cagtctgagg caccagcacc aagtcctact 180 tctggatcta gtgcgatctc agcgtctttc gtgtcagctg tgcagttatc accggcggag 240 agggaagcaa gggttttgag gtatagagag aagaggaaga atcggaaatt tgagaagacg 300 attaggtatg cgtcgcgtaa agcttacgct gagatgaggc cgagaatcaa aggacgtttt 360 gctaagagaa cagattcgag agagaatgat ggtggagacg tcggagttta ttgcggattc 420 ggtgttgttc cgagtttctg atatttcccg gttaaagaaa catggtagta gtatatcggt 480 taatagcaga ttaaggataa ttaaaactaa aatgtttcct gatttaatca ggggctaagt 540 tattgttaga agattgttgt tttttgaatt aattctcaca attgtatcct aaattatata 600 gtttacttaa tgttgaacta atg (2) INFORMATION FOR SEQ ID NO: 30:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 118 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..118
(D) OTHER INFORMATION: / Ceres Seq. ID 1010218
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 30:
Met Ala He Ser Lys Ala Ser He Val Val Leu Met Met Val He He
10 15
Ser Val Val Ala Ser Ala Gin Ser Glu Ala Pro Ala Pro Ser Pro Thr
20 25 30
Ser Gly Ser Ser Ala He Ser Ala Ser Phe Val Ser Ala Val Gin Leu
35 40 45
Ser Pro Ala Glu Arg Glu Ala Arg Val Leu Arg Tyr Arg Glu Lys Arg
50 55 60
Lys Asn Arg Lys Phe Glu Lys Thr He Arg Tyr Ala Ser Arg Lys Ala 65 70 75 80
Tyr Ala Glu Met Arg Pro Arg He Lys Gly Arg Phe Ala Lys Arg Thr
85 90 95
Asp Ser Arg Glu Asn Asp Gly Gly Asp Val Gly Val Tyr Cys Gly Phe
100 105 110
Gly Val Val Pro Ser Phe 115
(2) INFORMATION FOR SEQ ID NO: 31: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 107 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..107
(D) OTHER INFORMATION: / Ceres Seq. ID 1010219
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 31:
Met Met Val He He Ser Val Val Ala Ser Ala Gin Ser Glu Ala Pro
10 15
Ala Pro Ser Pro Thr Ser Gly Ser Ser Ala He Ser Ala Ser Phe Val 20 25 30
Ser Ala Val Gin Leu Ser Pro Ala Glu Arg Glu Ala Arg Val Leu Arg
35 40 45
Tyr Arg Glu Lys Arg Lys Asn Arg Lys Phe Glu Lys Thr He Arg Tyr
50 55 60
Ala Ser Arg Lys Ala Tyr Ala Glu Met Arg Pro Arg He Lys Gly Arg 65 70 75 80
Phe Ala Lys Arg Thr Asp Ser Arg Glu Asn Asp Gly Gly Asp Val Gly
85 90 95
Val Tyr Cys Gly Phe Gly Val Val Pro Ser Phe
100 105
(2) INFORMATION FOR SEQ ID NO: 32: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 106 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..106 (D) OTHER INFORMATION: / Ceres Seq. ID 1010220
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 32: Met Val He He Ser Val Val Ala Ser Ala Gin Ser Glu Ala Pro Ala 1 5 10 15
Pro Ser Pro Thr Ser Gly Ser Ser Ala He Ser Ala Ser Phe Val Ser
20 25 30
Ala Val Gin Leu Ser Pro Ala Glu Arg Glu Ala Arg Val Leu Arg Tyr
35 40 45
Arg Glu Lys Arg Lys Asn Arg Lys Phe Glu Lys Thr He Arg Tyr Ala
50 55 60
Ser Arg Lys Ala Tyr Ala Glu Met Arg Pro Arg He Lys Gly Arg Phe 65 70 75 80
Ala Lys Arg Thr Asp Ser Arg Glu Asn Asp Gly Gly Asp Val Gly Val
85 90 95
Tyr Cys Gly Phe Gly Val Val Pro Ser Phe 100 105
(2) INFORMATION FOR SEQ ID NO: 33:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 568 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..568
(D) OTHER INFORMATION: / Ceres Seq . ID 1010302 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 33: aaaacaaatc attcaaagac atacaaaata attgagtttt ttttttaatt agaaacaaat 60 ggggttgagt ggtgttcttc atgtggaggt tgaggttaag tctccggctg aaaagttctg 120 ggtagccctc ggcgacggca tcaatctctt ccccaaagct ttccctaacg actacaaaac 180 catccaagtt ctagccggcg acggcaacgc tcctggctcc attcgcctca ttacttatgg 240 agaaggatct ccactggtga agatatcggc ggagaggatc gaagcagtgg atttggagaa 300 caaaagcatg tcatacagca tcattggcgg cgaaatgttg gagtactaca aaacgttcaa 360 aggaaccatc accgttattc ctaagaacgg tggcagcctt ctgaaatggt ctggtgagtt 420 tgagaagacc gcccatgaga ttgatgaccc acacgtcatc aaggactttg ctgtcaagaa 480 cttcaaagag atagatgagt atctccttaa gcaaactagt gcctaacact agaaccttta 540 aattatataa gagggttcga tcgtctct (2) INFORMATION FOR SEQ ID NO: 34: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1010303 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 34: Met Gly Leu Ser Gly Val Leu His Val Glu Val Glu Val Lys Ser Pro 1 5 10 15
Ala Glu Lys Phe Trp Val Ala Leu Gly Asp Gly He Asn Leu Phe Pro
20 25 30
Lys Ala Phe Pro Asn Asp Tyr Lys Thr He Gin Val Leu Ala Gly Asp 35 40 45
Gly Asn Ala Pro Gly Ser He Arg Leu He Thr Tyr Gly Glu Gly Ser
50 55 60
Pro Leu Val Lys He Ser Ala Glu Arg He Glu Ala Val Asp Leu Glu 65 70 75 80 Asn Lys Ser Met Ser Tyr Ser He He Gly Gly Glu Met Leu Glu Tyr
85 90 95
Tyr Lys Thr Phe Lys Gly Thr He Thr Val He Pro Lys Asn Gly Gly
100 105 110
Ser Leu Leu Lys Trp Ser Gly Glu Phe Glu Lys Thr Ala His Glu He 115 120 125
Asp Asp Pro His Val He Lys Asp Phe Ala Val Lys Asn Phe Lys Glu
130 135 140
He Asp Glu Tyr Leu Leu Lys Gin Thr Ser Ala 145 150 155 (2) INFORMATION FOR SEQ ID NO: 35: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 531 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..531 (D) OTHER INFORMATION: / Ceres Seq. ID 1010815
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 35: gcgccgcccg aacccgaaga agaactctct cttgtaaacc tgcgatctga atcttcccgg 60 cggtgaaaaa tggttgcgga gaagaaggcg aagaagtccc atgaaggaat caacagcaga 120 ttagctcttg tgatgaagag tggaaagtac actcttggat acaagtctgt tctcaaatcc 180 cttcgcagct ccaaaggtaa gctgatattg atatctagca attgcccacc gttgagaagg 240 tcagagattg aatactatgc gatgcttgct aaagttggag ttcatcgcta caatggcaac 300 aatgttgatt tgggtactgc ttgtggtaaa tacttccgag tttcttgcct cagcatcgtt 360 gatcctggtg attccgacat catcaagaca cttcctggag atcagtgatt ctgattttga 420 tgattttgcc atgttgttct ctatgcttga ttatgctttg tgttcttcaa agacttaatg 480 ttagatttct ttggtttccc gacttcctct taatggttat aattaattac t (2) INFORMATION FOR SEQ ID NO:36: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 112 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..112
(D) OTHER INFORMATION: / Ceres Seq. ID 1010816 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 36: Met Val Ala Glu Lys Lys Ala Lys Lys Ser His Glu Gly He Asn Ser 1 5 10 15
Arg Leu Ala Leu Val Met Lys Ser Gly Lys Tyr Thr Leu Gly Tyr Lys 20 25 30 Ser Val Leu Lys Ser Leu Arg Ser Ser Lys Gly Lys Leu He Leu He 35 40 45
Ser Ser Asn Cys Pro Pro Leu Arg Arg Ser Glu He Glu Tyr Tyr Ala
50 55 60
Met Leu Ala Lys Val Gly Val His Arg Tyr Asn Gly Asn Asn Val Asp 65 70 75 80
Leu Gly Thr Ala Cys Gly Lys Tyr Phe Arg Val Ser Cys Leu Ser He
85 90 95
Val Asp Pro Gly Asp Ser Asp He He Lys Thr Leu Pro Gly Asp Gin 100 105 110 (2) INFORMATION FOR SEQ ID NO: 37: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 91 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..91 (D) OTHER INFORMATION: / Ceres Seq. ID 1010817
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 37: Met Lys Ser Gly Lys Tyr Thr Leu Gly Tyr Lys Ser Val Leu Lys Ser 1 5 ' 10 15
Leu Arg Ser Ser Lys Gly Lys Leu He Leu He Ser Ser Asn Cys Pro 20 25 30
Pro Leu Arg Arg Ser Glu He Glu Tyr Tyr Ala Met Leu Ala Lys Val
35 40 45
Gly Val His Arg Tyr Asn Gly Asn Asn Val Asp Leu Gly Thr Ala Cys 50 55 60 Gly Lys Tyr Phe Arg Val Ser Cys Leu Ser He Val Asp Pro Gly Asp 65 70 75 80
Ser Asp He He Lys Thr Leu Pro Gly Asp Gin
85 90
(2) INFORMATION FOR SEQ ID NO: 38: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 73 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..73
(D) OTHER INFORMATION: / Ceres Seq. ID 1010818 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 38:
Met Arg Cys Leu Leu Lys Leu Glu Phe He Ala Thr Met Ala Thr Met 1 5 10 15
Leu He Trp Val Leu Leu Val Val Asn Thr Ser Glu Phe Leu Ala Ser 20 25 30 Ala Ser Leu He Leu Val He Pro Thr Ser Ser Arg His Phe Leu Glu 35 40 45
He Ser Asp Ser Asp Phe Asp Asp Phe Ala Met Leu Phe Ser Met Leu
50 55 60
Asp Tyr Ala Leu Cys Ser Ser Lys Thr 65 70
(2) INFORMATION FOR SEQ ID NO:39: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 494 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic)
(ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..494
(D) OTHER INFORMATION: / Ceres Seq. ID 1011437 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 39: acaatcggaa gaaaggagaa gacgaagatg tcgttggtat ggctggaagc gatgttgcct 60 ctcggaatca tcggtgggat gctctgtatc atgggcaatt ctcagtacta catccacaaa 120 gcttatcatg gccgtcctaa gcacatcggc cacgatgaat gggatgtttc tatggaaaga 180 cgcgacaaga aagtcgtcga gaaagctgca gctccttcct catgattcgc tttatctctt 240 ttgtgttcct caggggctta aggtgaccac ttgtggtgac aaataaagtg cattccagaa 300 gaagaagaag ctgggggatc tagtactttc attcccattt gattttcctt ggacatatta 360 aagctttcag aaatcagacc tcaataacat ttggtttatc aatatttctc tattcgtgat 420 attttgtatg cttttaagtt gcatgataca ctgaactact ctcttgctgt gtgagtgaat 480 aaatgaatat ctgt
(2) INFORMATION FOR SEQ ID NO: 40: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 94 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..94 (D) OTHER INFORMATION: / Ceres Seq. ID 1011438
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 40: Gin Ser Glu Glu Arg Arg Arg Arg Arg Cys Arg Trp Tyr Gly Trp Lys 1 5 10 15
Arg Cys Cys Leu Ser Glu Ser Ser Val Gly Cys Ser Val Ser Trp Ala
20 25 30
He Leu Ser Thr Thr Ser Thr Lys Leu He Met Ala Val Leu Ser Thr
35 40 45
Ser Ala Thr Met Asn Gly Met Phe Leu Trp Lys Asp Ala Thr Arg Lys
50 55 60
Ser Ser Arg Lys Leu Gin Leu Leu Pro His Asp Ser Leu Tyr Leu Phe 65 70 75 80
Cys Val Pro Gin Gly Leu Lys Val Thr Thr Cys Gly Asp Lys 85 90
(2) INFORMATION FOR SEQ ID NO: 41:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 1011439 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 41: Thr He Gly Arg Lys Glu Lys Thr Lys Met Ser Leu Val Trp Leu Glu 1 5 10 15
Ala Met Leu Pro Leu Gly He He Gly Gly Met Leu Cys He Met Gly
20 25 30
Asn Ser Gin Tyr Tyr He His Lys Ala Tyr His Gly Arg Pro Lys His
35 40 45
He Gly His Asp Glu Trp Asp Val Ser Met Glu Arg Arg Asp Lys Lys 50 55 60
Val Val Glu Lys Ala Ala Ala Pro Ser Ser
65 70
(2) INFORMATION FOR SEQ I D NO : 42 :
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1011440
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 42:
Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He He Gly
10 15
Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His Lys Ale
20 25 30
Tyr His Gly Arg Pro Lys His He Gly His Asp Glu Trp Asp Val Ser
35 40 45
Met Glu Arg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala Pro Ser
50 55 60
Ser
65
(2) INFORMATION FOR SEQ ID NO: 43: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1011 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..1011
(D) OTHER INFORMATION: / Ceres Seq. ID 1011616 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 43: ctgtttcttt ttgcttcctt agacttctcc gtcgattaac ccttgccgag ggtcattttt 60 ttttcttgaa ttttttcacc aagtgttcgt tcacggcatt gcttgtcctc cagtatgagt 120 atctccggtg ctgcagttgg ttcaggcaga aatttaagaa gagcggtaga gtttgggaaa 180 actcatgtgg ttaggcctaa agggaaacat caagcaacta ttgtctggtt acatgggctt 240 ggggacaatg gctcgagctg gtcccagctt ttggagaccc ttccccttcc aaatatcaaa 300 tggatttgcc cgactgctcc ttctcaacca ataagtttat ttggtggttt tccctccaca 360 gcttggtttg atgttgtgga catcaatgaa gatggacctg atgatatgga aggattggat 420 gtggctgctg cacatgttgc aaatctgttg tcgaatgagc ctgctgacat taaattaggt 480 gttggaggat tcagcatggg tgcggcgaca tctctatatt ctgcaacttg ttttgctctc 540 ggtaaatatg gaaatggcaa tccataccct atcaatttaa gcgcaatcat aggcttaagc 600 ggctggcttc cttgtgcaaa gacattggct ggcaaactag aagaggaaca gatcaagaac 660 cgagctgcat cgttacccat tgttgtctgt catggaaaag ctgatgatgt ggtaccgttc 720 aagtttgggg agaaatcttc acaggctttg ctttcaaatg ggtttaagaa ggtgaccttc 780 aaaccttaca gtgcacttgg tcaccacaca atcccacagg agttggatga gttgtgcgca 840 tggttgacat ccacgctcag cctcgaaggt tgatacttcc tatgatgtag ctttctgatg 900 aaaacccttc aactcttgag agtttgattg aattggatgt ttcaggattt cacaatgttt 960 tcattggaat atttgtgtaa gacacattcg tctagtagca aatcttctcc c (2) INFORMATION FOR SEQ ID NO: 44:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 252 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE : (A) NAME/KEY: peptide
(B) LOCATION: 1..252
(D) OTHER INFORMATION: / Ceres Seq. ID 1011617 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 44: Met Ser He Ser Gly Ala Ala Val Gly Ser Gly Arg Asn Leu Arg Arg 1 5 10 15
Ala Val Glu Phe Gly Lys Thr His Val Val Arg Pro Lys Gly Lys His
20 25 30
Gin Ala Thr He Val Trp Leu His Gly Leu Gly Asp Asn Gly Ser Ser 35 40 45
Trp Ser Gin Leu Leu Glu Thr Leu Pro Leu Pro Asn He Lys Trp He
50 55 60
Cys Pro Thr Ala Pro Ser Gin Pro He Ser Leu Phe Gly Gly Phe Pro 65 70 75 80 Ser Thr Ala Trp Phe Asp Val Val Asp He Asn Glu Asp Gly Pro Asp
85 90 95
Asp Met Glu Gly Leu Asp Val Ala Ala Ala His Val Ala Asn Leu Leu
100 105 110
Ser Asn Glu Pro Ala Asp He Lys Leu Gly Val Gly Gly Phe Ser Met 115 120 125
Gly Ala Ala Thr Ser Leu Tyr Ser Ala Thr Cys Phe Ala Leu Gly Lys
130 135 140
Tyr Gly Asn Gly Asn Pro Tyr Pro He Asn Leu Ser Ala He He Gly 145 150 155 160 Leu Ser Gly Trp Leu Pro Cys Ala Lys Thr Leu Ala Gly Lys Leu Glu
165 170 175
Glu Glu Gin He Lys Asn Arg Ala Ala Ser Leu Pro He Val Val Cys
180 185 190
His Gly Lys Ala Asp Asp Val Val Pro Phe Lys Phe Gly Glu Lys Ser 195 200 205
Ser Gin Ala Leu Leu Ser Asn Gly Phe Lys Lys Val Thr Phe Lys Pro
210 215 220
Tyr Ser Ala Leu Gly His His Thr He Pro Gin Glu Leu Asp Glu Leu 225 230 235 240 Cys Ala Trp Leu Thr Ser Thr Leu Ser Leu Glu Gly
245 250
(2) INFORMATION FOR SEQ ID NO: 45: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1011618 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 45: Met Glu Gly Leu Asp Val Ala Ala Ala His Val Ala Asn Leu Leu Ser 1 5 10 15
Asn Glu Pro Ala Asp He Lys Leu Gly Val Gly Gly Phe Ser Met Gly
20 25 30
Ala Ala Thr Ser Leu Tyr Ser Ala Thr Cys Phe Ala Leu Gly Lys Tyr 35 40 45 Gly Asn Gly Asn Pro Tyr Pro He Asn Leu Ser Ala He He Gly Leu 50 55 60
Ser Gly Trp Leu Pro Cys Ala Lys Thr Leu Ala Gly Lys Leu Glu Glu 65 70 75 80
Glu Gin He Lys Asn Arg Ala Ala Ser Leu Pro He Val Val Cys His 85 90 95
Gly Lys Ala Asp Asp Val Val Pro Phe Lys Phe Gly Glu Lys Ser Ser 100 105 110 Gin Ala Leu Leu Ser Asn Gly Phe Lys Lys Val Thr Phe Lys Pro Tyr
115 120 125
Ser Ala Leu Gly His His Thr He Pro Gin Glu Leu Asp Glu Leu Cys
130 135 140
Ala Trp Leu Thr Ser Thr Leu Ser Leu Glu Gly
145 150 155 (2) INFORMATION FOR SEQ ID NO: 46:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 643 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..643 (D) OTHER INFORMATION: / Ceres Seq. ID 1011631
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 46: agaatgtgat ggagatggga gtgaatgaga tgagtggtgg gattaaagaa gagaagaagg 60 agaaggctct tatgcttaga ttggactatg aatcagtcat ttccacttgg ggaggccaag 120 ggatcccatg gaccgcccgg gtgccatctg aaatagacct cgacatggtt tgtttcccaa 180 cccataccat gggtgaaagt ggagcagagg ctcatcatca caaccacttc cgcggcctag 240 ggttacacct aggagatgct ggggatggag gaagagaggc tagggtttca agataccgag 300 agaaaaggag gacaaggttg ttctccaaga agataaggta cgaggtacgt aaattgaatg 360 cagagaaaag gcctcgcatg aaaggaaggt tcgtcaagag atcttcaatt ggtgttgctc 420 actaaagaac ttaattaatt atggatatta aattactttg ctctcatctt gcttttttgt 480 tgctatagtt ttggtgattg ttagctttct ttttctgcat tcatagagaa ttttgcacgt 540 ttttgtgagc tacgtatgta cataaatata tcaccaaaaa aatgtgacta tcttgtaagc 600 actgatttat atagtcgata taacgtgaat tttgattgct ggc (2) INFORMATION FOR SEQ ID NO: 47: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 140 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..140
(D) OTHER INFORMATION: / Ceres Seq. ID 1011632 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 47: Asn Val Met Glu Met Gly Val Asn Glu Met Ser Gly Gly He Lys Glu 1 5 10 15
Glu Lys Lys Glu Lys Ala Leu Met Leu Arg Leu Asp Tyr Glu Ser Val
20 25 30
He Ser Thr Trp Gly Gly Gin Gly He Pro Trp Thr Ala Arg Val Pro
35 40 45
Ser Glu He Asp Leu Asp Met Val Cys Phe Pro Thr His Thr Met Gly
50 55 60
Glu Ser Gly Ala Glu Ala His His His Asn His Phe Arg Gly Leu Gly 65 70 75 80
Leu His Leu Gly Asp Ala Gly Asp Gly Gly Arg Glu Ala Arg Val Ser
85 90 95
Arg Tyr Arg Glu Lys Arg Arg Thr Arg Leu Phe Ser Lys Lys He Arg
100 105 110
Tyr Glu Val Arg Lys Leu Asn Ala Glu Lys Arg Pro Arg Met Lys Gly
115 120 125
Arg Phe Val Lys Arg Ser Ser He Gly Val Ala His 130 135 140
(2) INFORMATION FOR SEQ ID NO: 48: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 138 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..138
(D) OTHER INFORMATION: / Ceres Seq. ID 1011633 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 48: Met Glu Met Gly Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys 1 5 10 15
Lys Glu Lys Ala Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser
20 25 30
Thr Trp Gly Gly Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu 35 40 45
He Asp Leu Asp Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser
50 55 60
Gly Ala Glu Ala His His His Asn His Phe Arg Gly Leu Gly Leu His 65 70 75 80 Leu Gly Asp Ala Gly Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr
85 90 95
Arg Glu Lys Arg Arg Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu
100 105 110
Val Arg Lys Leu Asn Ala Glu Lys Arg Pro Arg Met Lys Gly Arg Phe 115 120 125
Val Lys Arg Ser Ser He Gly Val Ala His
130 135
(2) INFORMATION FOR SEQ ID NO: 49: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 136 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..136
(D) OTHER INFORMATION: / Ceres Seq. ID 1011634 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 49: Met Gly Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu 1 5 10 15
Lys Ala Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp
20 25 30
Gly Gly Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp 35 40 45
Leu Asp Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala
50 55 60
Glu Ala His His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly 65 70 75 80 Asp Ala Gly Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr Arg Glu
85 90 95
Lys Arg Arg Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg
100 105 110
Lys Leu Asn Ala Glu Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys 115 120 125
Arg Ser Ser He Gly Val Ala His
130 135
(2) INFORMATION FOR SEQ ID NO: 50: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 663 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single ( D) TOPOLOGY : linear
( ϋ ) MOLECULE TYPE : DNA ( genomic ) ( ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..663 (D) OTHER INFORMATION: / Ceres Seq. ID 1011714
(xi ) SEQUENCE DESCRIPTION: SEQ ID NO: 50: gtgttcgata ataatgtcga caggagaagc gataccaaga gtcgccgtcg tcgttttcat 60 tctcaacgga aactcaatct tattaggtcg ccgccgttcc tcaatcggca actccacttt 120 cgctcttccc ggtggccacc tcgaattcgg agagagcttt gaagaatgtg cagcgagaga 180 agtaatggag gaaacaggtc taaagattga aaagatgaag cttttgactg ttacaaacaa 240 tgtcttcaaa gaagcaccaa cgccatcaca ctacgtctct gtttcgatac gtgcggtgtt 300 ggtggatcca agtcaagaac cgaagaatat ggaaccagag aagtgtgaag gatgggattg 360 gtatgattgg gagaatctac caaagccttt gttttggcca cttgagaaat tgtttggaag 420 tggtttcaat cctttcactc atggtggtgg agactaatag atgtaagagt taatgattga 480 tttgggattg aatgttgcaa attgggcatt tggtctagtg gtatgattct cgcttagggt 540 gcgagaggtc ccgagttcaa ttctcggaat gcccctctct tttactcttt tttattgtat 600 ttttggtttc tgttttccta attagtaata aacttatcat gtgtcctatc gattttattt 660 etc (2) INFORMATION FOR SEQ ID NO: 51:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..151
(D) OTHER INFORMATION: / Ceres Seq. ID 1011715 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:51: Cys Ser He He Met Ser Thr Gly Glu Ala He Pro Arg Val Ala Val 1 5 10 15
Val Val Phe He Leu Asn Gly Asn Ser He Leu Leu Gly Arg Arg Arg
20 25 30
Ser Ser He Gly Asn Ser Thr Phe Ala Leu Pro Gly Gly His Leu Glu
35 40 45
Phe Gly Glu Ser Phe Glu Glu Cys Ala Ala Arg Glu Val Met Glu Glu
50 55 60
Thr Gly Leu Lys He Glu Lys Met Lys Leu Leu Thr Val Thr Asn Asn 65 70 75 80
Val Phe Lys Glu Ala Pro Thr Pro Ser His Tyr Val Ser Val Ser He
85 90 95
Arg Ala Val Leu Val Asp Pro Ser Gin Glu Pro Lys Asn Met Glu Pro
100 105 110
Glu Lys Cys Glu Gly Trp Asp Trp Tyr Asp Trp Glu Asn Leu Pro Lys
115 120 125
Pro Leu Phe Trp Pro Leu Glu Lys Leu Phe Gly Ser Gly Phe Asn Pro
130 135 140
Phe Thr His Gly Gly Gly Asp 145 150
(2) INFORMATION FOR SEQ ID NO: 52:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 147 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..147
(D) OTHER INFORMATION: / Ceres Seq. ID 1011716 (xi ) SEQUENCE DESCRIPTION : SEQ I D NO : 52 : Met Ser Thr Gly Glu Ala He Pro Arg Val Ala Val Val Val Phe He 1 5 10 15
Leu Asn Gly Asn Ser He Leu Leu Gly Arg Arg Arg Ser Ser He Gly
20 25 30
Asn Ser Thr Phe Ala Leu Pro Gly Gly His Leu Glu Phe Gly Glu Ser
35 40 45
Phe Glu Glu Cys Ala Ala Arg Glu Val Met Glu Glu Thr Gly Leu Lys
50 55 60
He Glu Lys Met Lys Leu Leu Thr Val Thr Asn Asn Val Phe Lys Glu 65 70 75 80
Ala Pro Thr Pro Ser His Tyi Val Ser Val Ser He Arg Ala Val Leu
85 90 95
Val Asp Pro Ser Gin Glu Pro Lys Asn Met Glu Pro Glu Lys Cys Glu
100 105 110
Gly Trp Asp Trp Tyr Asp Trp Glu Asn Leu Pro Lys Pro Leu Phe Trp
115 120 125
Pro Leu Glu Lys Leu Phe Gly Ser Gly Phe Asn Pro Phe Thr His Gly
130 135 140
Gly Gly Asp 145
(2) INFORMATION FOR SEQ ID NO: 53:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 90 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..90 (D) OTHER INFORMATION: / Ceres Seq. ID 1011717
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:53: Met Glu Glu Thr Gly Leu Lys He Glu Lys Met Lys Leu Leu Thr Val 1 5 10 15
Thr Asn Asn Val Phe Lys Glu Ala Pro Thr Pro Ser His Tyr Val Ser
20 25 30
Val Ser He Arg Ala Val Leu Val Asp Pro Ser Gin Glu Pro Lys Asn
35 40 45
Met Glu Pro Glu Lys Cys Glu Gly Trp Asp Trp Tyr Asp Trp Glu Asn
50 55 60
Leu Pro Lys Pro Leu Phe Trp Pro Leu Glu Lys Leu Phe Gly Ser Gly 65 70 75 80
Phe Asn Pro Phe Thr His Gly Gly Gly Asp 85 90
(2) INFORMATION FOR SEQ ID NO: 54:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 524 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..524
(D) OTHER INFORMATION: / Ceres Seq. ID 1011784 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 54: aaaacagaac aaacacaaac acaaacagag aatcaacgaa gaagaaaaat ggtgaaggtg 60 atgtgggttt ccgttttagc tctggcggcg gcgattctcc ttttgacggt cccggtggca 120 gaaggggtga cgtgctcgcc tatgcagctg gcttcatgtg cggcggcgat gacgtcatct 180 tcgccgccat cggaggcgtg ttgcacaaag ctgagagagc agcagccatg cctttgtggg 240 tacatgagga accctaccct ccgccaatac gttagctccc ctaacgcaag gaaagtctcc 300 aacagttgca agattccttc cccaagctgt taaggaaatg ttaatcatga ttaattagtg 360 acaagtttcg ctgattatag tggttaatgc tggtcttatc ttcgtcagta ctacttaaaa 420 taataaatga gtgatgatga ttgatgatta tcatcatcat gcttgaatgt tatgttttct 480 atcttataaa atatgaaata tactttagaa atatgtttcg tcgt (2) INFORMATION FOR SEQ ID NO: 55: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 110 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..110 (D) OTHER INFORMATION: / Ceres Seq. ID 1011785
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 55: Lys Thr Glu Gin Thr Gin Thr Gin Thr Glu Asn Gin Arg Arg Arg Lys 1 5 10 15
Met Val Lys Val Met Trp Val Ser Val Leu Ala Leu Ala Ala Ala He 20 25 30
Leu Leu Leu Thr Val Pro Val Ala Glu Gly Val Thr Cys Ser Pro Met
35 40 45
Gin Leu Ala Ser Cys Ala Ala Ala Met Thr Ser Ser Ser Pro Pro Ser 50 55 60 Glu Ala Cys Cys Thr Lys Leu Arg Glu Gin Gin Pro Cys Leu Cys Gly 65 70 75 80
Tyr Met Arg Asn Pro Thr Leu Arg Gin Tyr Val Ser Ser Pro Asn Ala
85 90 95
Arg Lys Val Ser Asn Ser Cys Lys He Pro Ser Pro Ser Cys 100 105 110
(2) INFORMATION FOR SEQ ID NO: 56: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 94 amino aciαs
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..94
(D) OTHER INFORMATION: / Ceres Seq. ID 1011786 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 56: Met Val Lys Val Met Trp Val Ser Val Leu Ala Leu Ala Ala Ala He 1 5 10 15 Leu Leu Leu Thr Val Pro Val Ala Glu Gly Val Thr Cys Ser Pro Met 20 25 30
Gin Leu Ala Ser Cys Ala Ala Ala Met Thr Ser Ser Ser Pro Pro Ser
35 40 45
Glu Ala Cys Cys Thr Lys Leu Arg Glu Gin Gin Pro Cys Leu Cys Gly 50 55 60
Tyr Met Arg Asn Pro Thr Leu Arg Gin Tyr Val Ser Ser Pro Asn Ala 65 70 75 80
Arg Lys Val Ser Asn Ser Cys Lys He Pro Ser Pro Ser Cys 85 90 (2) INFORMATION FOR SEQ ID NO: 57: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 90 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..90
(D) OTHER INFORMATION: / Ceres Seq. ID 1011787 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 57: Asn Arg Thr Asn Thr Asn Thr Asn Arg Glu Ser Thr Lys Lys Lys Asn 1 5 10 15
Gly Glu Gly Asp Val Gly Phe Arg Phe Ser Ser Gly Gly Gly Asp Ser
20 25 30
Pro Phe Asp Gly Pro Gly Gly Arg Arg Gly Asp Val Leu Ala Tyr Ala
35 40 45
Ala Gly Phe Met Cys Gly Gly Asp Asp Val He Phe Ala Ala He Gly
50 55 60
Gly Val Leu His Lys Ala Glu Arg Ala Ala Ala Met Pro Leu Trp Val 65 70 75 80
His Glu Glu Pro Tyr Pro Pro Pro He Arg
85 90
(2) INFORMATION FOR SEQ ID NO: 58: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1007 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1007
(D) OTHER INFORMATION: / Ceres Seq. ID 1011820 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 58: ccaaatttct ccatggatcg ttctttgaat ctcctcgatt tagccttagg gttcgatgag 60 cagctagcta ttccatcgcc actaaatgga aaagtaatac taatagaaga ctgtgtagag 120 acgagtggtt cctttgtact tcaccagcta atgaaacgtg ttctctcctc taactcctcc 180 gacgcactta tctttctcgc ttttgctcgc cctttctctc attatgatcg aatcttgcgt 240 aaactgggat gtaatttagc tacccataag tcgaataatc gattggtgtt ctttgacatg 300 ctcatggtta agtgttcaga tggggatcaa atggaagaca atgtgagtgc agttgcgaaa 360 ctatttcggg agatacaaga aaccgttcga aagctacaga gtgtaacaag tggtaacata 420 actgttatgg tggatgacat gtctctgctg gaaattgcta ctaccggcag caactcagat 480 cacgtattgg acttcttgca ttattgccac acattaagtt ctgaaagcaa ttgttcattg 540 gtcatcctca atcatgaaga tatatacgcg agcatggaga gacctgcatt tttgctacag 600 atggtatgcc ttgcagatgt tgtgataaag gcagagcctt tagcctctgg tttagcaaat 660 gatgtacatg gccaattgac tgttctgaac aaagggataa gcaactcagg tagaggaagc 720 tcgaggaaca agttgcagaa ttttcaattc aggatcaagg aaaatggtat cgactatttc 780 tatcctggtt gcagaagctg aggattagac accgttctga gcattagcat ggtagtgaga 840 tgcatctaga cagttttgtt atttgcgttt aggttaaaca gagacactct gttcaacatt 900 tttactttag tgtctcttct ggttgtaact tgatgactta gctaaagttg aatgcttgag 960 acacagaaac ttgtagacat ggaaaattag taacattcta tatcttt (2) INFORMATION FOR SEQ ID NO: 59:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 266 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..266
(D) OTHER INFORMATION: / Ceres Seq. ID 1011821 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 59: Pro Asn Phe Ser Met Asp Arg Ser Leu Asn Leu Leu Asp Leu Ala Leu 1 5 10 15
Gly Phe Asp Glu Gin Leu Ala He Pro Ser Pro Leu Asn Gly Lys Val
20 25 30
He Leu He Glu Asp Cys Val Glu Thr Ser Gly Ser Phe Val Leu His 35 40 45
Gin Leu Met Lys Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He
50 55 60
Phe Leu Ala Phe Ala Arg Pro Phe Ser His Tyr Asp Arg He Leu Arg 65 70 75 80
Lys Leu Gly Cys Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val
85 90 95
Phe Phe Asp Met Leu Met Val Lys Cys Ser Asp Gly Asp Gin Met Glu 100 105 110 Asp Asn Val Ser Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr 115 120 125
Val Arg Lys Leu Gin Ser Val Thr Ser Gly Asn He Thr Val Met Val
130 135 140
Asp Asp Met Ser Leu Leu Glu He Ala Thr Thr Gly Ser Asn Ser Asp 145 150 155 160
His Val Leu Asp Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser
165 170 175
Asn Cys Ser Leu Val He Leu Asn His Glu Asp He Tyr Ala Ser Met 180 185 190 Glu Arg Pro Ala Phe Leu Leu Gin Met Val Cys Leu Ala Asp Val Val 195 200 205
He Lys Ala Glu Pro Leu Ala Ser Gly Leu Ala Asn Asp Val His Gly
210 215 220
Gin Leu Thr Val Leu Asn Lys Gly He Ser Asn Ser Gly Arg Gly Ser 225 230 235 240
Ser Arg Asn Lys Leu Gin Asn Phe Gin Phe Arg He Lys Glu Asn Gly
245 250 255
He Asp Tyr Phe Tyr Pro Gly Cys Arg Ser 260 265 (2) INFORMATION FOR SEQ ID NO: 60: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 262 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..262 (D) OTHER INFORMATION: / Ceres Seq. ID 1011822
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 60: Met Asp Arg Ser Leu Asn Leu Leu Asp Leu Ala Leu Gly Phe Asp Glu 1 5 10 15
Gin Leu Ala He Pro Ser Pro Leu Asn Gly Lys Val He Leu He Glu 20 25 30
Asp Cys Val Glu Thr Ser Gly Ser Phe Val Leu His Gin Leu Met Lys
35 40 45
Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He Phe Leu Ala Phe 50 55 60 Ala Arg Pro Phe Ser His Tyr Asp Arg He Leu Arg Lys Leu Gly Cys 65 70 75 80
Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val Phe Phe Asp Met
85 90 95
Leu Met Val Lys Cys Ser Asp Gly Asp Gin Met Glu Asp Asn Val Ser 100 105 110
Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr Val Arg Lys Leu
115 120 125
Gin Ser Val Thr Ser Gly Asn He Thr Val Met Val Asp Asp Met Ser
130 135 140 Leu Leu Glu He Ala Thr Thr Gly Ser Asn Ser Asp His Val Leu Asp
145 150 155 160
Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser Asn Cys Ser Leu 165 170 175
Val He Leu Asn His Glu Asp He Tyr Ala Ser Met Glu Arg Pro Ala
180 185 190
Phe Leu Leu Gin Met Val Cys Leu Ala Asp Val Val He Lys Ala Glu 195 200 205
Pro Leu Ala Ser Gly Leu Ala Asn Asp Val His Gly Gin Leu Thr Val
210 215 220
Leu Asn Lys Gly He Ser Asn Ser Gly Arg Gly Ser Ser Arg Asn Lys 225 230 235 240 Leu Gin Asn Phe Gin Phe Arg He Lys Glu Asn Gly He Asp Tyr Phe
245 250 255
Tyr Pro Gly Cys Arg Ser
260 (2) INFORMATION FOR SEQ ID NO: 61: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 216 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..216
(D) OTHER INFORMATION: / Ceres Seq. ID 1011823 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 61:
Met Lys Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He Phe Leu 1 5 10 15
Ala Phe Ala Arg Pro Phe Ser His Tyr Asp Arg He Leu Arg Lys Leu 20 25 30 Gly Cys Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val Phe Phe 35 40 45
Asp Met Leu Met Val Lys Cys Ser Asp Gly Asp Gin Met Glu Asp Asn
50 55 60
Val Ser Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr Val Arg 65 70 75 80
Lys Leu Gin Ser Val Thr Ser Gly Asn He Thr Val Met Val Asp Asp
85 90 95
Met Ser Leu Leu Glu He Ala Thr Thr Gly Ser Asn Ser Asp His Val 100 105 110 Leu Asp Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser Asn Cys 115 120 125
Ser Leu Val He Leu Asn His Glu Asp He Tyr Ala Ser Met Glu Arg
130 135 140
Pro Ala Phe Leu Leu Gin Met Val Cys Leu Ala Asp Val Val He Lys 145 150 155 160
Ala Glu Pro Leu Ala Ser Gly Leu Ala Asn Asp Val His Gly Gin Leu
165 170 175
Thr Val Leu Asn Lys Gly He Ser Asn Ser Gly Arg Gly Ser Ser Arg 180 185 190 Asn Lys Leu Gin Asn Phe Gin Phe Arg He Lys Glu Asn Gly He Asp 195 200 205
Tyr Phe Tyr Pro Gly Cys Arg Ser
210 215
(2) INFORMATION FOR SEQ ID NO: 62: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 584 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..584
(D) OTHER INFORMATION: / Ceres Seq. ID 1011874 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 62: tcaattaaca taaccttcgc cgtcgatgaa gctttccctt caattcccac taccttcagc 60 gtcgcaacga aacaacacta cgacgtaaaa ccaatccacc atgaagttta tgacggagaa 120 aggaagatat acgacatcag ccaccagtac acgccggagt tgccggtttg ggagtcttca 180 gaaggactag ggaactttct tagacttgcc gtgagtatga agaatggatc cgatgctaat 240 atctcgaaga tggaactatc tgttcactct ggaactcatg ttgatgcacc aggccatttc 300 catgaccatt attatgagtc tggttttgat actgattcac ttgatcttca aatccttaat 360 ggtaaacatt tttggaactc tttttttttt ttttttttaa gtagctagtg atcgtttttg 420 aaattggttt ctgtgaattt aatttatagg tcctgcttta ttggttgatg ttccaagaga 480 taagaacatt tcaggtttgt tgagagtttt ctaacattga aatttttaca aaatcttcat 540 taaatgtttg ttacaaaatt tttgtgtaat gatttggttg ttgt (2) INFORMATION FOR SEQ ID NO: 63: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 135 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..135 (D) OTHER INFORMATION: / Ceres Seq. ID 1011875
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 63:
Ser He Asn He Thr Phe Ala Val Asp Glu Ala Phe Pro Ser He Pro
1 5 10 15
Thr Thr Phe Ser Val Ala Thr Lys Gin His Tyr Asp Val Lys Pro He
20 25 30
His His Glu Val Tyr Asp Gly Glu Arg Lys He Tyr Asp He Ser His
35 40 45
Gin Tyr Thr Pro Glu Leu Pro Val Trp Glu Ser Ser Glu Gly Leu Gly
50 55 60
Asn Phe Leu Arg Leu Ala Val Ser Met Lys Asn Gly Ser Asp Ala Asn
65 70 75 .0
He Ser Lys Met Glu Leu Ser Val His Ser Gly Thr His Val Asp Ala
90 95
Pro Gly His Phe His Asp His Tyr Tyr Glu Ser Gly Phe Asp Thr Asp
100 105 110
Ser Leu Asp Leu Gin He Leu Asn Gly Lys His Phe Trp Asn Ser Phe
115 120 125 Phe Phe Phe Phe Leu Ser Ser
130 135
(2) INFORMATION FOR SEQ ID NO: 64: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 626 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..626
(D) OTHER INFORMATION: / Ceres Seq. ID 1011981 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 64: acatcctaat cgaaaaaaac cctagcaaaa acctctctct ctctctcaat tcacttctcc 60 tcctacaatg gcttggcgca acgcaggatc tgctgctcgt tctttcgtct ccgccaccgc 120 aagatcacca tctctccgtt ctcccaccac ggcgcttcct cgcctccgtc ctcctcaatc 180 ctccttacct agccgtcgct tcaccttctc gtcaccttcc aggaatctag gagccctagg 240 ttgcacacag tcgttcttgc ctctgtacag tgttgtggct acttctcaac tgacatctca 300 ccttaacgtt aatttgcgag ctttctgcga gctgtctaac ggtacttgaa gaggcaaaag 360 agtgtaattt cactgcgcat gcgtgaatca gtactttgaa gggatgtgag atcgaaattg 420 tgggattacc tcagcaaaaa cttgcttaat gtgttgcctg ttttagaagt tttagtttca 480 caatgtgtgg atttattagt tgtagagctt ttcgtatgct tggcacaatg gttttttctc 540 agagaacctt tttttgtttt ggagaaatgc atagcagcat taataagtgt attggatcag 600 aactgaaaca atgttgttac tgattc (2) INFORMATION FOR SEQ ID NO: 65: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 93 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..93 (D) OTHER INFORMATION: / Ceres Seq. ID 1011982
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 65: Met Ala Trp Arg Asn Ala Gly Ser Ala Ala Arg Ser Phe Val Ser Ala 1 5 10 15
Thr Ala Arg Ser Pro Ser Leu Arg Ser Pro Thr Thr Ala Leu Pro Arg 20 25 30
Leu Arg Pro Pro Gin Ser Ser Leu Pro Ser Arg Arg Phe Thr Phe Ser
35 40 45
Ser Pro Ser Arg Asn Leu Gly Ala Leu Gly Cys Thr Gin Ser Phe Leu 50 55 60 Pro Leu Tyr Ser Val Val Ala Thr Ser Gin Leu Thr Ser His Leu Asn 65 70 75 80
Val Asn Leu Arg Ala Phe Cys Glu Leu Ser Asn Gly Thr
85 90
(2) INFORMATION FOR SEQ ID NO: 66: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 75 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..75
(D) OTHER INFORMATION: / Ceres Seq. ID 1011983 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 66:
He Leu He Glu Lys Asn Pro Ser Lys Asn Leu Ser Leu Ser Leu Asn 1 5 10 15
Ser Leu Leu Leu Leu Gin Trp Leu Gly Ala Thr Gin Asp Leu Leu Leu 20 25 30 Val Leu Ser Ser Pro Pro Pro Gin Asp His His Leu Ser Val Leu Pro 35 40 45
Pro Arg Arg Phe Leu Ala Ser Val Leu Leu Asn Pro Pro Tyr Leu Ala
50 55 60
Val Ala Ser Pro Ser Arg His Leu Pro Gly He 65 70 75
(2) INFORMATION FOR SEQ ID NO: 67: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 46 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..46
(D) OTHER INFORMATION: / Ceres Seq. ID 1011984 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 67: Met Cys Gly Phe He Ser Cys Arg Ala Phe Arg Met Leu Gly Thr Met 1 5 10 15
Val Phe Ser Gin Arg Thr Phe Phe Cys Phe Gly Glu Met His Ser Ser 20 25 30 He Asn Lys Cys He Gly Ser Glu Leu Lys Gin Cys Cys Tyr 35 40 45
(2) INFORMATION FOR SEQ ID NO: 68: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 468 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..468
(D) OTHER INFORMATION: / Ceres Seq. ID 1014547 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 68: atagaatata accatattcc ggacatgaag atcgtgacat tggtactcgt cgtcttcgtc 60 atactttcga catcattccc ggctgccatc aaagccgaag acacgggaga tacaggaaat 120 gtgggagtga catgtgacgc aaggcagctt cagccttgcc ttgccgcgat tacgggagga 180 ggacaaccct cgggtgcatg ttgtgcaaag cttacagagc aacagtcatg cctatgtggt 240 ttcgctaaga accctgcgtt cgcacagtac attagctctc caaacgctcg caaagtgctc 300 cttgcttgca atgttgctta tcccacttgt tgaaacttat ctagatttta taaataaata 360 aacgaaagga aataaattac attatatcaa acgttatgat acaattcaac cgtttgtgtt 420 aatgtactgg cttacatggt taaataaagt ttaatttctt ggttgctc (2) INFORMATION FOR SEQ ID NO: 69: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 110 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..110
(D) OTHER INFORMATION: / Ceres Seq. ID 1014548 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 69: He Glu Tyr Asn His He Pro Asp Met Lys He Val Thr Leu Val Leu 1 5 10 15
Val Val Phe Val He Leu Ser Thr Ser Phe Pro Ala Ala He Lys Ala
20 25 30
Glu Asp Thr Gly Asp Thr Gly Asn Val Gly Val Thr Cys Asp Ala Arg 35 40 45 Gin Leu Gin Pro Cys Leu Ala Ala He Thr Gly Gly Gly Gin Pro Ser 50 55 60
Gly Ala Cys Cys Ala Lys Leu Thr Glu Gin Gin Ser Cys Leu Cys Gly 65 70 75 80
Phe Ala Lys Asn Pro Ala Phe Ala Gin Tyr He Ser Ser Pro Asn Ala 85 90 95
Arg Lys Val Leu Leu Ala Cys Asn Val Ala Tyr Pro Thr Cys 100 105 110
(2) INFORMATION FOR SEQ ID NO: 70: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 102 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..102 (D) OTHER INFORMATION: / Ceres Seq. ID 1014549 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 70: Met Lys He Val Thr Leu Val Leu Val Val Phe Val He Leu Ser Thr 1 5 10 15
Ser Phe Pro Ala Ala He Lys Ala Glu Asp Thr Gly Asp Thr Gly Asn
20 25 30
Val Gly Val Thr Cys Asp Ala Arg Gin Leu Gin Pro Cys Leu Ala Ala
35 40 45
He Thr Gly Gly Gly Gin Pro Ser Gly Ala Cys Cys Ala Lys Leu Thr
50 55 60
Glu Gin Gin Ser Cys Leu Cys Gly Phe Ala Lys Asn Pro Ala Phe Ala
65 70 75 .0
Gin Tyr He Ser Ser Pro Asn Ala Arg Lys Val Leu Leu Ala Cys Asn
85 90 95 Val Ala Tyr Pro Thr Cys 100
(2) INFORMATION FOR SEQ ID NO: 71:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1303 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..1303
(D) OTHER INFORMATION: / Ceres Seq. ID 1014995 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 71: aaaactcaag tttcttgcaa ttacctactt acaacaaagc aactcgactc gaacaaacac 60 atccatggct ccttctgcgc aacctcttcc tgtgagtgtt tcggatgaaa aatatgcgaa 120 tgtcaagtgg gaagagttgg cattcaagtt tgttcgtacg gattatatgt atgttgcgaa 180 gtgcaatcat ggagagagtt ttcaagaggg gaagattctt ccttttgctg atttgcaact 240 taacccttgc gctgctgttc ttcagtatgg ccagggttta tatgaaggac tgaaagctta 300 caggacagaa gatggtcgga ttctgctatt ccgaccagac caaaacggtc tccgccttca 360 agccggagct gacagactct atatgcctta tccttcggtc gatcaattcg tctccgccat 420 caaacaagtt gctcttgcca acaagaaatg gattcctcct ccggggaaag gaacattgta 480 tattaggcct atcttgtttg ggagtggtcc gattcttggt tcatttccca ttcctgagac 540 caccttcaca gcttttgcct gtcctgttgg acgttatcat aaggataact ctggtttgaa 600 tctgaaaatc gaagatcagt ttcgtcgagc ttttcctagt ggaactggtg gtgtgaagag 660 catcacaaac tattgtcctg tttggatacc attggcagag gcgaaaaaac aaggtttctc 720 tgatattttg tttttggatg ctgcaactgg caaaaacatt gaagaacttt tcgcagctaa 780 tgtttttatg ctcaagggca atgttgtatc gacaccaaca attgcaggaa ctattttgcc 840 cggagtcact cgaaactgcg taatggaatt gtgtcgtgat ttcggctacc aggtcgagga 900 acgtacgatt cctctagtgg actttctcga tgcggacgaa gctttctgta ctggcactgc 960 ttccattgtg actagtattg catccgtaac ctttaaagac aaaaagaccg gattcaaaac 1020 agggaagaaa cattggctgc gaagctatac gagacgttaa gtgatatcca gacgggtcgg 1080 gtcgaggata ccaagggatg gacggtggag attgaccgcc agggctgaaa gttgaaactg 1140 taacttgatg ctaaatatgt gtgtgtgtgt atacaaaact tatgtaagaa acatctgaag 1200 atgtctctga tctttgtgat tgtgatgatc atgcatgtcc tatcgttgcg atgtatttta 1260 taaatgttcg tctgtaagtt atttaataac tatggctttt tgc (2) INFORMATION FOR SEQ ID NO: 72:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 352 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..352
(D) OTHER INFORMATION: / Ceres Seq. ID 1014996
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 72: Lys Leu Lys Phe Leu Ala He Thr Tyr Leu Gin Gin Ser Asn Ser Thr 1 5 10 15
Arg Thr Asn Thr Ser Met Ala Pro Ser Ala Gin Pro Leu Pro Val Ser 20 25 30 Val Ser Asp Glu Lys Tyr Ala Asn Val Lys Trp Glu Glu Leu Ala Phe 35 40 45
Lys Phe Val Arg Thr Asp Tyr Met Tyr Val Ala Lys Cys Asn His Gly
50 55 60
Glu Ser Phe Gin Glu Gly Lys He Leu Pro Phe Ala Asp Leu Gin Leu 65 70 75 80
Asn Pro Cys Ala Ala Val Leu Gin Tyr Gly Gin Gly Leu Tyr Glu Gly
85 90 95
Leu Lys Ala Tyr Arg Thr Glu Asp Gly Arg He Leu Leu Phe Arg Pro 100 105 110 Asp Gin Asn Gly Leu Arg Leu Gin Ala Gly Ala Asp Arg Leu Tyr Met 115 120 125
Pro Tyr Pro Ser Val Asp Gin Phe Val Ser Ala He Lys Gin Val Ala
130 135 140
Leu Ala Asn Lys Lys Trp He Pro Pro Pro Gly Lys Gly Thr Leu Tyr 145 150 155 160
He Arg Pro He Leu Phe Gly Ser Gly Pro He Leu Gly Ser Phe Pro
165 170 175
He Pro Glu Thr Thr Phe Thr Ala Phe Ala Cys Pro Val Gly Arg Tyr 180 185 190 His Lys Asp Asn Ser Gly Leu Asn Leu Lys He Glu Asp Gin Phe Arg 195 200 205
Arg Ala Phe Pro Ser Gly Thr Gly Gly Val Lys Ser He Thr Asn Tyr
210 215 220
Cys Pro Val Trp He Pro Leu Ala Glu Ala Lys Lys Gin Gly Phe Ser 225 230 235 240
Asp He Leu Phe Leu Asp Ala Ala Thr Gly Lys Asn He Glu Glu Leu
245 250 255
Phe Ala Ala Asn Val Phe Met Leu Lys Gly Asn Val Val Ser Thr Pro 260 265 270 Thr He Ala Gly Thr He Leu Pro Gly Val Thr Arg Asn Cys Val Met 275 280 285
Glu Leu Cys Arg Asp Phe Gly Tyr Gin Val Glu Glu Arg Thr He Pro
290 295 300
Leu Val Asp Phe Leu Asp Ala Asp Glu Ala Phe Cys Thr Gly Thr Ala 305 310 315 320
Ser He Val Thr Ser He Ala Ser Val Thr Phe Lys Asp Lys Lys Thr
325 330 335
Gly Phe Lys Thr Gly Lys Lys His Trp Leu Arg Ser Tyr Thr Arg Arg 340 345 350 (2) INFORMATION FOR SEQ ID NO:73: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 331 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..331 (D) OTHER INFORMATION: / Ceres Seq. ID 1014997
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:73: Met Ala Pro Ser Ala Gin Pro Leu Pro Val Ser Val Ser Asp Glu Lys 1 5 10 15
Tyr Ala Asn Val Lys Trp Glu Glu Leu Ala Phe Lys Phe Val Arg Thr 20 25 30
Asp Tyr Met Tyr Val Ala Lys Cys Asn His Gly Glu Ser Phe Gin Glu 35 40 45 Gly Lys He Leu Pro Phe Ala Asp Leu Gin Leu Asn Pro Cys Ala Ala
50 55 60
Val Leu Gin Tyr Gly Gin Gly Leu Tyr Glu Gly Leu Lys Ala Tyr Arg 65 70 75 80 Thr Glu Asp Gly Arg He Leu Leu Phe Arg Pro Asp Gin Asn Gly Leu
85 90 95
Arg Leu Gin Ala Gly Ala Asp Arg Leu Tyr Met Pro Tyr Pro Ser Val
100 105 110
Asp Gin Phe Val Ser Ala He Lys Gin Val Ala Leu Ala Asn Lys Lys 115 120 125
Trp He Pro Pro Pro Gly Lys Gly Thr Leu Tyr He Arg Pro He Leu
130 135 140
Phe Gly Ser Gly Pro He Leu Gly Ser Phe Pro He Pro Glu Thr Thr 145 150 155 160 Phe Thr Ala Phe Ala Cys Pro Val Gly Arg Tyr His Lys Asp Asn Ser
165 170 175
Gly Leu Asn Leu Lys He Glu Asp Gin Phe Arg Arg Ala Phe Pro Ser
180 185 190
Gly Thr Gly Gly Val Lys Ser He Thr Asn Tyr Cys Pro Val Trp He 195 200 205
Pro Leu Ala Glu Ala Lys Lys Gin Gly Phe Ser Asp He Leu Phe Leu
210 215 220
Asp Ala Ala Thr Gly Lys Asn He Glu Glu Leu Phe Ala Ala Asn Val 225 230 235 240 Phe Met Leu Lys Gly Asn Val Val Ser Thr Pro Thr He Ala Gly Thr
245 250 255
He Leu Pro Gly Val Thr Arg Asn Cys Val Met Glu Leu Cys Arg Asp
260 265 270
Phe Gly Tyr Gin Val Glu Glu Arg Thr He Pro Leu Val Asp Phe Leu 275 280 285
Asp Ala Asp Glu Ala Phe Cys Thr Gly Thr Ala Ser He Val Thr Ser
290 295 300
He Ala Ser Val Thr Phe Lys Asp Lys Lys Thr Gly Phe Lys Thr Gly 305 310 315 320 Lys Lys His Trp Leu Arg Ser Tyr Thr Arg Arg
325 330
(2) INFORMATION FOR SEQ ID NO: 74: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 297 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..297
(D) OTHER INFORMATION: / Ceres Seq. ID 1014998 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:74: Met Tyr Val Ala Lys Cys Asn His Gly Glu Ser Phe Gin Glu Gly Lys 1 5 10 15
He Leu Pro Phe Ala Asp Leu Gin Leu Asn Pro Cys Ala Ala Val Leu
20 25 30
Gin Tyr Gly Gin Gly Leu Tyr Glu Gly Leu Lys Ala Tyr Arg Thr Glu 35 40 45 Asp Gly Arg He Leu Leu Phe Arg Pro Asp Gin Asn Gly Leu Arg Leu 50 55 60
Gin Ala Gly Ala Asp Arg Leu Tyr Met Pro Tyr Pro Ser Val Asp Gin 65 70 75 80
Phe Val Ser Ala He Lys Gin Val Ala Leu Ala Asn Lys Lys Trp He 85 90 95
Pro Pro Pro Gly Lys Gly Thr Leu Tyr He Arg Pro He Leu Phe Gly 100 105 110 Ser Gly Pro He Leu Gly Ser Phe Pro He Pro Glu Thr Thr Phe Thr
115 120 125
Ala Phe Ala Cys Pro Val Gly Arg Tyr His Lys Asp Asn Ser Gly Leu
130 135 140
Asn Leu Lys He Glu Asp Gin Phe Arg Arg Ala Phe Pro Ser Gly Thr 145 150 155 160
Gly Gly Val Lys Ser He Thr Asn Tyr Cys Pro Val Trp He Pro Leu
165 170 175
Ala Glu Ala Lys Lys Gin Gly Phe Ser Asp He Leu Phe Leu Asp Ala 180 185 190
Ala Thr Gly Lys Asn He Glu Glu Leu Phe Ala Ala Asn Val Phe Met
195 200 205
Leu Lys Gly Asn Val Val Ser Thr Pro Thr He Ala Gly Thr He Leu
210 215 220
Pro Gly Val Thr Arg Asn Cys Val Met Glu Leu Cys Arg Asp Phe Gly 225 230 235 240
Tyr Gin Val Glu Glu Arg Thr He Pro Leu Val Asp Phe Leu Asp Ala
245 250 255
Asp Glu Ala Phe Cys Thr Gly Thr Ala Ser He Val Thr Ser He Ala 260 265 270
Ser Val Thr Phe Lys Asp Lys Lys Thr Gly Phe Lys Thr Gly Lys Lys
275 280 285
His Trp Leu Arg Ser Tyr Thr Arg Arg
290 295
(2) INFORMATION FOR SEQ ID NO: 75: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 789 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..789
(D) OTHER INFORMATION: / Ceres Seq. ID 101532 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 75: gggttaggtt tgtcttcaaa atcgtcagaa gaagaagaag aagtcaaaga cgataacaat 60 gacgtcatca tcgtacctcc gatttgcgat cgccgtcgta gctttcctct caatcaccac 120 catcaccacc gcacgtcctt gcaaaacctt cctaatctcc tcatattccc tctcaataac 180 cccagaaaac cctaacctcg aatccgattt cacctccaca cgattcgtca ccgttttcac 240 aatccgtcgt ctaaatcctc accacgtggt tcctttcttc gtcaatcgtc gtcacgagaa 300 gccacagatc caatcggatc gttccctccc tttgatctct gataacatca attcgtttag 360 agatcgaacc agagatattc ttagcgtcgt cgtcgcgctt ttgttcggtg ttggttgtgg 420 tgctttaacc gctgctacta tgtatcttgt ttgggctctt gttgtgaatc gtcaaagcta 480 tgattttgag gaagaagaag atgattatga gaatgatgaa tctgatgctg ctagcttgaa 540 gaaattgggt tatgttaaga ttccagctcc agctcctgct cctgtgaagg aagctgcttg 600 atttgaggtt gtgaatttca gtttctgcat attatcatga tttacgttgt tgcttatcta 660 tgttgttgcg tacaagtaaa ttcgtctctg ttatggattt atctaaactt actatactct 720 aagtatcagt gtttttacga tttgtagttg atgtttctta tatatatata taagtgtgat 780 tatgatgtc
(2) INFORMATION FOR SEQ ID NO: 76: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 180 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE :
(A) NAME/KEY peptide
(B) LOCATION 1..180
(D) OTHER INFORMATION: / Ceres Seq. ID 1015324
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 76: Met Thr Ser Ser Ser Tyr Leu Arg Phe Ala He Ala Val Val Ala Phe
1 5 10 15
Leu Ser He Thr Thr He Thr Thr Ala Arg Pro Cys Lys Thr Phe Leu
20 25 30
He Ser Ser Tyr Ser Leu Ser He Thr Pro Glu Asn Pro Asn Leu Glu
35 40 45
Ser Asp Phe Thr Ser Thr Arg Phe Val Thr Val Phe Thr He Arg Arg
50 55 60
Leu Asn Pro His His Val Val Pro Phe Phe Val Asn Arg Arg His Glu 65 70 75 80
Lys Pro Gin He Gin Ser Asp Arg Ser Leu Pro Leu He Ser Asp Asn
85 90 95
He Asn Ser Phe Arg Asp Arg Thr Arg Asp He Leu Ser Val Val Val
100 105 110
Ala Leu Leu Phe Gly Val Gly Cys Gly Ala Leu Thr Ala Ala Thr Met
115 120 125
Tyr Leu Val Trp Ala Leu Val Val Asn Arg Gin Ser Tyr Asp Phe Glu
130 135 140
Glu Glu Glu Asp Asp Tyr Glu Asn Asp Glu Ser Asp Ala Ala Ser Leu 145 150 155 160
Lys Lys Leu Gly Tyr Val Lys He Pro Ala Pro Ala Pro Ala Pro Val
165 170 175
Lys Glu Ala Ala 180 (2) INFORMATION FOR SEQ ID NO: 77:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 495 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..495
(D) OTHER INFORMATION: / Ceres Seq. ID 1016486 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 77: acttcctcat tagcattcta cagtctgcac acttatcact tctttcgaaa tctctctcta 60 tccctctcaa aaatgaagct ctctgtgcgt tttatctccg ctgctcttct cttgttcatg 120 gtattcattg ccacagggat gggtccagtc accgtggagg cacgcacgtg tgagtcaaag 180 agccataggt tcaagggtcc atgtgtgagc acacacaact gtgcaaacgt gtgccacaac 240 gaaggcttcg gcggaggtaa atgccgtgga ttccgtcgtc gttgctactg cacaagacac 300 tgctgatcca tccattctca tgactcaaat cttcgatcca tcgtcagtgt gttacttctt 360 tcttatctaa atcttccgta cggtaccata tcgtaccgta catgagtgtt ttctcaaata 420 agtcgttggt ttgtgtgttt ccggttttaa tgtaatgtta aatcaattaa tggcttttaa 480 tatattgtat tatgg
(2) INFORMATION FOR SEQ ID NO:78: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 101 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..101
(D) OTHER INFORMATION: / Ceres Seq. ID 1016487 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:78: Thr Ser Ser Leu Ala Phe Tyr Ser Leu His Thr Tyr His Phe Phe Arg 1 5 10 15
Asn Leu Ser Leu Ser Leu Ser Lys Met Lys Leu Ser Val Arg Phe He
20 25 30
Ser Ala Ala Leu Leu Leu Phe Met Val Phe He Ala Thr Gly Met Gly 35 40 45
Pro Val Thr Val Glu Ala Arg Thr Cys Glu Ser Lys Ser His Arg Phe
50 55 60
Lys Gly Pro Cys Val Ser Thr His Asn Cys Ala Asn Val Cys His Asn 65 70 75 80
Glu Gly Phe Gly Gly Gly Lys Cys Arg Gly Phe Arg Arg Arg Cys Tyr
85 90 95
Cys Thr Arg His Cys 100 (2) INFORMATION FOR SEQ ID NO: 79: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 77 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..77 (D) OTHER INFORMATION: / Ceres Seq. ID 1016488
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:79: Met Lys Leu Ser Val Arg Phe He Ser Ala Ala Leu Leu Leu Phe Met 1 5 10 15
Val Phe He Ala Thr Gly Met Gly Pro Val Thr Val Glu Ala Arg Thr 20 25 30
Cys Glu Ser Lys Ser His Arg Phe Lys Gly Pro Cys Val Ser Thr His
35 40 45
Asn Cys Ala Asn Val Cys His Asn Glu Gly Phe Gly Gly Gly Lys Cys 50 55 60 Arg Gly Phe Arg Arg Arg Cys Tyr Cys Thr Arg His Cys 65 70 75
(2) INFORMATION FOR SEQ ID NO: 80: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 62 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..62
(D) OTHER INFORMATION: / Ceres Seq. ID 1016489 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 80: Met Val Phe He Ala Thr Gly Met Gly Pro Val Thr Val Glu Ala Arg 1 5 10 15
Thr Cys Glu Ser Lys Ser His Arg Phe Lys Gly Pro Cys Val Ser Thr
20 25 30
His Asn Cys Ala Asn Val Cys His Asn Glu Gly Phe Gly Gly Gly Lys 35 40 45 Cys Arg Gly Phe Arg Arg Arg Cys Tyr Cys Thr Arg His Cys 50 55 60
(2) INFORMATION FOR SEQ ID NO: 81: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 325 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..325
(D) OTHER INFORMATION: / Ceres Seq. ID 1018341 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 81: atcatcaaac acaaaacaat caatcaaaaa cataaaattc aaagtgtaag caaaaccaga 60 acgagagaaa atggacaaca agcaaaacgc gagctaccaa gccggtcaag ccactggcca 120 gactaaggag aaggccggtg gaatgatgga caaggccaag gatgctgctg cttcagctca 180 agactccttg caacagactg gacaacaaat gaaggagaag gcgcaaggag ctgctgatgt 240 cgtcaaggac aagaccggca tgaacaaaag ccactaagca agcatcttgg acttcttttc 300 taattaattc ccctcttcga cttgt (2) INFORMATION FOR SEQ ID NO: 82:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 68 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..68
(D) OTHER INFORMATION: / Ceres Seq. ID 1018342
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 82:
Met Asp Asn Lys Gin Asn Ala Ser Tyr Gin Ala Gly Gin Ala Thr Gly
1 5 10 15
Gin Thr Lys Glu Lys Ala Gly Gly Met Met Asp Lys Ala Lys Asp Ala
20 25 30
Ala Ala Ser Ala Gin Asp Ser Leu Gin Gin Thr Gly Gin Gin Met Lys
35 40 45
Glu Lys Ala Gin Gly Ala Ala Asp Val Val Lys Asp Lys Thr Gly Met
50 55 60
Asn Lys Ser His 65
(2) INFORMATION FOR SEQ ID NO: 83: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 44 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..44 (D) OTHER INFORMATION: / Ceres Seq. ID 1018343
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 83: Met Met Asp Lys Ala Lys Asp Ala Ala Ala Ser Ala Gin Asp Ser Leu 1 5 10 15
Gin Gin Thr Gly Gin Gin Met Lys Glu Lys Ala Gin Gly Ala Ala Asp
20 25 30
Val Val Lys Asp Lys Thr Gly Met Asn Lys Ser His 35 40
(2) INFORMATION FOR SEQ ID NO: 84:
SEQUENCE CHARACTERISTICS:
(A) LENGTH: 43 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..43 (D) OTHER INFORMATION: / Ceres Seq. ID 1018344
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 84: Met Asp Lys Ala Lys Asp Ala Ala Ala Ser Ala Gin Asp Ser Leu Gin 1 5 10 15
Gin Thr Gly Gin Gin Met Lys Glu Lys Ala Gin Gly Ala Ala Asp Val 20 25 30
Val Lys Asp Lys Thr Gly Met Asn Lys Ser His
35 40
(2) INFORMATION FOR SEQ ID NO: 85: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 540 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..540
(D) OTHER INFORMATION: / Ceres Seq. ID 1018382
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 85: taaaagcaat aaaaaacaaa aatggcgttt actccgaaga tcatcacatg cctcattgtc 60 cttacgatct acatgacatc cccaacagag tcaaccatcc agtgtgggac agtgacgagc 120 acactggcac agtgcgtgac ctacttgacc aacagtggtc cattgccatc acaatgctgc 180 gtgggagtca agtcattgta ccaattggct cagaccacac cggaccgtaa acaagtatgt 240 gagtgcctta aactagcggg taaagaaatc aagggcctca acaccgacct tgtggccgca 300 cttcctacca cttgtggtgt ttcaattccc taccccatca gttttagcac caattgcgac 360 agtatatcga ctgccgtgtg aaagaggcta gtgatcagat gtacgactaa tcaaacttgc 420 cagcttttaa cctaattaaa taaaagtatt ctgcttatat ttcccatttt atgattttat 480 cttcttatct atgtaaccac acgatttcat atgctaataa tgacaacgga tctttctctc 540 (2) INFORMATION FOR SEQ ID NO: 86: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 119 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..119
(D) OTHER INFORMATION: ; / Ceres ! Seq. ID 1018383
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 86:
Met Ala Phe Thr Pro Lys He He Thr Cys Leu He Val Leu Thr He
1 5 10 15
Tyr Met Thr Ser Pro Thr Glu Ser Thr He Gin Cys Gly Thr Val Thr 20 25 30
Ser Thr Leu Ala Gin Cys Val Thr Tyr Leu Thr Asn Ser Gly Pro Leu 35 40 45
Pro Ser Gin Cys Cys Val Gly Val Lys Ser Leu Tyr Gin Leu Ala Gin 50 55 60
Thr Thr Pro Asp Arg Lys Gin Val Cys Glu Cys Leu Lys Leu Ala Gly
65 70 75 80
Lys Glu He Lys Gly Leu Asn Thr Asp Leu Val Ala Ala Leu Pro Thr 85 90 95
Thr Cys Gly Val Ser He Pro Tyr Pro He Ser Phe Ser Thr Asn Cys 100 105 110
Asp Ser He Ser Thr Ala Val 115
(2) INFORMATION FOR SEQ ID I SIO: 87:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..102 (D) OTHER INFORMATION: / Ceres Seq. ID 1018384 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 87: Met Thr Ser Pro Thr Glu Ser Thr He Gin Cys Gly Thr Val Thr Ser 1 5 10 15
Thr Leu Ala Gin Cys Val Thr Tyr Leu Thr Asn Ser Gly Pro Leu Pro
20 25 30
Ser Gin Cys Cys Val Gly Val Lys Ser Leu Tyr Gin Leu Ala Gin Thr
35 40 45
Thr Pro Asp Arg Lys Gin Val Cys Glu Cys Leu Lys Leu Ala Gly Lys
50 55 60
Glu He Lys Gly Leu Asn Thr Asp Leu Val Ala Ala Leu Pro Thr Thr 65 70 75 80
Cys Gly Val Ser He Pro Tyr Pro He Ser Phe Ser Thr Asn Cys Asp
85 90 95
Ser He Ser Thr Ala Val 100
(2) INFORMATION FOR SEQ ID NO: 88: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 75 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..75 (D) OTHER INFORMATION: / Ceres Seq. ID 1018385
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 88: Lys Ala He Lys Asn Lys Asn Gly Val Tyr Ser Glu Asp His His Met 1 5 10 15
Pro His Cys Pro Tyr Asp Leu His Asp He Pro Asn Arg Val Asn His
20 25 30
Pro Val Trp Asp Ser Asp Glu His Thr Gly Thr Val Arg Asp Leu Leu
35 40 45
Asp Gin Gin Trp Ser He Ala He Thr Met Leu Arg Gly Ser Gin Val
50 55 60
He Val Pro He Gly Ser Asp His Thr Gly Pro
65 70 75
(2) INFORMATION FOR SEQ ID NO: 89:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 844 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..844
(D) OTHER INFORMATION: / Ceres Seq. ID 10206 66 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 89: ctaaatattt aaagctttcc ttcaccagca ttgtattgcc tccctggaac accgaagctc 60 tggattaacc tattttcacc ttctaaggtt cttcgtcgtt cttattgatc tgtgaagatg 120 tattcgggtc agaacaagat ccacaaggat aagggtgttg caccaacaga gtttgaagag 180 caagttactc aggctttgtt tgacttggag aacaccaacc aggagttgaa aagcgagttg 240 aaagatctct acattaacca agctgttcag atggatattt ctggcaaccg caaagctgtt 300 gtgatctacg ttccattcag gctgaggaaa gctttccgca agattcatct tcgtctggtc 360 agagagcttg agaagaagtt cagtggaaaa gatgtgatct ttgttgctac cagaagaatc 420 atgcgcccac caaagaaagg ctcagctgtt cagagaccac gcaacagaac tcttacttct 480 gtccatgaag ccatgctcga ggatgtcgct taccctgctg agattgtagg aaagagaacc 540 agataccgtc ttgatggcac caagatcatg aaggtatttt tggatagtaa gctaaagaac 600 gacactgagt acaagctgga gacaatggtg ggtgtgtaca gaaaacttac agggaaagat 660 gtagttttcg agtacccagt catagaagct tgaagagatg aatgtttgtt tcattctttt 720 ttgtcggata gagagctttt gattctgttt gggagtaaaa ctctttgcaa agattttgtt 780 atttcagcat ttcgcaatct cttcttcaaa gttcgattta tcgatacaat tcttttttcc 840 tacc
(2) INFORMATION FOR SEQ ID NO: 90: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 191 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..191
(D) OTHER INFORMATION: / Ceres Seq. ID 1020667 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 90:
Met Tyr Ser Gly Gin Asn Lys He His Lys Asp Lys Gly Val Ala Pro 1 5 10 15
Thr Glu Phe Glu Glu Gin Val Thr Gin Ala Leu Phe Asp Leu Glu Asn 20 25 30 Thr Asn Gin Glu Leu Lys Ser Glu Leu Lys Asp Leu Tyr He Asn Gin 35 40 45
Ala Val Gin Met Asp He Ser Gly Asn Arg Lys Ala Val Val He Tyr
50 55 60
Val Pro Phe Arg Leu Arg Lys Ala Phe Arg Lys He His Leu Arg Leu 65 70 75 80
Val Arg Glu Leu Glu Lys Lys Phe Ser Gly Lys Asp Val He Phe Val
85 90 95
Ala Thr Arg Arg He Met Arg Pro Pro Lys Lys Gly Ser Ala Val Gin 100 105 110 Arg Pro Arg Asn Arg Thr Leu Thr Ser Val His Glu Ala Met Leu Glu 115 120 125
Asp Val Ala Tyr Pro Ala Glu He Val Gly Lys Arg Thr Arg Tyr Arg
130 135 140
Leu Asp Gly Thr Lys He Met Lys Val Phe Leu Asp Ser Lys Leu Lys 145 150 155 160
Asn Asp Thr Glu Tyr Lys Leu Glu Thr Met Val Gly Val Tyr Arg Lys
165 170 175
Leu Thr Gly Lys Asp Val Val Phe Glu Tyr Pro Val He Glu Ala 180 185 190 (2) INFORMATION FOR SEQ ID NO: 91: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 140 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..140 (D) OTHER INFORMATION: / Ceres Seq. ID 1020668
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 91: Met Asp He Ser Gly Asn Arg Lys Ala Val Val He Tyr Val Pro Phe 1 5 10 15
Arg Leu Arg Lys Ala Phe Arg Lys He His Leu Arg Leu Val Arg Glu 20 25 30
Leu Glu Lys Lys Phe Ser Gly Lys Asp Val He Phe Val Ala Thr Arg
35 40 45
Arg He Met Arg Pro Pro Lys Lys Gly Ser Ala Val Gin Arg Pro Arg 50 55 60 Asn Arg Thr Leu Thr Ser Val His Glu Ala Met Leu Glu Asp Val Ala 65 70 75 80
Tyr Pro Ala Glu He Val Gly Lys Arg Thr Arg Tyr Arg Leu Asp Gly 85 90 95
Thr Lys He Met Lys Val Phe Leu Asp Ser Lys Leu Lys Asn Asp Thr 100 105 110
Glu Tyr Lys Leu Glu Thr Met Val Gly Val Tyr Arg Lys Leu Thr Gly
115 120 125
Lys Asp Val Val Phe Glu Tyr Pro Val He Glu Ala 130 135 140
(2) INFORMATION FOR SEQ ID NO: 92: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 789 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..789
(D) OTHER INFORMATION: / Ceres Seq. ID 1020784 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 92: agggttaggt ttgtcttcaa aatcgtcaga agaagaagaa gaagtcaaag acgataacaa 60 tgacgtcatc atcgtacctc cgatttgcga tcgccgtcgt agctttcctc tcaatcacca 120 ccatcaccac cgcacgtcct tgcaaaacct tcctaatctc ctcatattcc ctctcaataa 180 ccccagaaaa ccctaacctc gaatccgatt tcacctccac acgattcatc accgttttca 240 caatccgtcg tctaaatcct caccacgtgg ttcctttctt cgtcaatcgt cgtcacgaga 300 agccacagat ccaatcggat cgttccctcc ctttgatctc tgataacatc aattcgttta 360 gagatcgaac cagagatatt cttagcgtcg tcgtcgcgct tttgttcggt gttggttgtg 420 gtgctttaac cgctgctact atgtatcttg tttgggctct tgttgtgaat cgtcaaagct 480 atgattttga ggaagaagaa gatgattatg agaatgatga atctgatgct gctagcttga 540 agaaattggg ttatgttaag attccagctc cagctcctgc tcctgtgaag gaagctgctt 600 gatttgaggt tgtgaatttc agtttctgca tattatcatg atttacgttg ttgcttatct 660 atgttgttgc gtacaagtaa attcgtctct gttatggatt tatctaaact tactatactc 720 taagtatcag tgtttttacg atttgtagtt gatgtttctt atatatatat ataagtgtga 780 ttatgatgc
(2) INFORMATION FOR SEQ ID NO: 93: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 180 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..180 (D) OTHER INFORMATION: / Ceres Seq. ID 1020785
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 93:
Met Thr Ser Ser Ser Tyr Leu Arg Phe Ala He Ala Val Val Ala Phe
10 15
Leu Ser He Thr Thr He Thr Thr Ala Arg Pro Cys Lys Thr Phe Leu
20 25 30
He Ser Ser Tyr Ser Leu Ser He Thr Pro Glu Asn Pro Asn Leu Glu
35 40 45
Ser Asp Phe Thr Ser Thr Arg Phe He Thr Val Phe Thr He Arg Arg
50 55 60
Leu Asn Pro His His Val Val Pro Phe Phe Val Asn Arg Arg His Glu 65 70 75 80
Lys Pro Gin He Gin Ser Asp Arg Ser Leu Pro Leu He Ser Asp Asn
85 90 95
He Asn Ser Phe Arg Asp Arg Thr Arg Asp He Leu Ser Val Val Val
100 105 110
Ala Leu Leu Phe Gly Val Gly Cys Gly Ala Leu Thr Ala Ala Thr Met
115 120 125
Tyr Leu Val Trp Ala Leu Val Val Asn Arg Gin Ser Tyr Asp Phe Glu 130 135 140
Glu Glu Glu Asp Asp Tyr Glu Asn Asp Glu Ser Asp Ala Ala Ser Leu 145 150 155 160
Lys Lys Leu Gly Tyr Val Lys He Pro Ala Pro Ala Pro Ala Pro Val
165 170 175
Lys Glu Ala Ala 180
(2) INFORMATION FOR SEQ ID NO: 94:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 765 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1.-.765
(D) OTHER INFORMATION: / Ceres Seq. ID 1021525 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 94: accctcactc acttttccgg tttcaaccat tagcacaaaa aatctgagct ccgaccaaaa 60 attggggaac gacgatggcg acgactcttc agaaactctc ctctcaaatc caccgactct 120 ctccattcac cagatctcta atcgttcgca catccgcaac gtctgctcct tctccgtctc 180 tgggatcgaa gaaagtctct gaccgaatcg tcaagctttc tgcgatcgat cccgatggat 240 acaagcagga catcattgga ctctctggcc agactctcct tcgtgcgctc actcacactg 300 gtctgataga tccagcatcg catagattgg atgacatcga ggcttgctca gcggagtgcg 360 aggttcagat cgcagaggaa tggctcgaga agctcccgcc gcgtacttac gatgaggagt 420 atgtgctgaa gcgtagctct agatcccgta tcttgaacaa gcactcgcgt cttggttgcc 480 aagttgtgtt aacgcaggag cttcaaggta tggtcgtcgc tgtccctgaa gctaagcctt 540 gggatattcc gtaagttttt gttcttgagg atctcataaa tgttgggttc gttctcaatt 600 tggctaataa aattcgcttt ggaaatttcg gtactctgaa gataactcca tttgaatctg 660 taattttcgt ttgcttacat ttaaattttg taatgtggta aagaactctg cttgtttaaa 720 cgattccctg cttcaagtat gggtgaatgt tgttttcttg attcc (2) INFORMATION FOR SEQ ID NO: 95: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 159 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..159
(D) OTHER INFORMATION: / Ceres Seq. ID 1021526 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 95: Met Ala Thr Thr Leu Gin Lys Leu Ser Ser Gin He His Arg Leu Ser 1 5 10 15
Pro Phe Thr Arg Ser Leu He Val Arg Thr Ser Ala Thr Ser Ala Pro
20 25 30
Ser Pro Ser Leu Gly Ser Lys Lys Val Ser Asp Arg He Val Lys Leu
35 40 45
Ser Ala He Asp Pro Asp Gly Tyr Lys Gin Asp He He Gly Leu Ser
50 55 60
Gly Gin Thr Leu Leu Arg Ala Leu Thr His Thr Gly Leu He Asp Pro 65 70 75 80
Ala Ser His Arg Leu Asp Asp He Glu Ala Cys Ser Ala Glu Cys Glu
85 90 95
Val Gin He Ala Glu Glu Trp Leu Glu Lys Leu Pro Pro Arg Thr Tyr
100 105 110
Asp Glu Glu Tyr Val Leu Lys Arg Ser Ser Arg Ser Arg He Leu Asn
115 120 125
Lys His Ser Arg Leu Gly Cys Gin Val Val Leu Thr Gin Glu Leu Gin 130 135 140 Gly Met Val Val Ala Val Pro Glu Ala Lys Pro Trp Asp He Pro 145 150 155
(2) INFORMATION FOR SEQ ID NO: 96: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 588 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..588
(D) OTHER INFORMATION: / Ceres Seq. ID 1021563 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 96: atcttcggaa agtctcattt ctcgatcccc aattcgtgga ttagggttaa aagaaccatt 60 tttattctcg tcgcgcaaca acaaatccag atcgaaaaag gaagaagaga tcgaaatggc 120 tttgagaagg gtttacagtg aaatcagagg gaagaaggtg acggagcttc caggctatat 180 caaatcgact ttttcaatgg agaccgtgaa gacctctgtg aagagaggac tcgataacta 240 caacgaaaaa tacattcaga ccagctccgt tgatcctatc cttcatatct gcttctacgg 300 catggctttc tcttaccttg tcgctctc.cc taatgagcgt cgccatcttg agcatcagca 360 gcatgctaag gagcacggtg gtcattgatc tcgtgggaat cgtttcgatc tcgagatgat 420 tttagggggg ttgctgtgaa atctttctct gcttgatggt gacgacgact caagaattgt 480 gtcttattgt ttcgttttct tgaattttcc tggataatgt tgacctaaag gaaaaccttt 540 ctttcgaatt acactccatg atagtcaata attgaagcat catgatgc (2) INFORMATION FOR SEQ ID NO: 97: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 128 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..128 (D) OTHER INFORMATION: / Ceres Seq. ID 1021564
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 97: Ser Ser Glu Ser Leu He Ser Arg Ser Pro He Arg Gly Leu Gly Leu 1 5 10 15
Lys Glu Pro Phe Leu Phe Ser Ser Arg Asn Asn Lys Ser Arg Ser Lys 20 25 30
Lys Glu Glu Glu He Glu Met Ala Leu Arg Arg Val Tyr Ser Glu He
35 40 45
Arg Gly Lys Lys Val Thr Glu Leu Pro Gly Tyr He Lys Ser Thr Phe 50 55 60 Ser Met Glu Thr Val Lys Thr Ser Val Lys Arg Gly Leu Asp Asn Tyr 65 70 75 80
Asn Glu Lys Tyr He Gin Thr Ser Ser Val Asp Pro He Leu His He
85 90 95
Cys Phe Tyr Gly Met Ala Phe Ser Tyr Leu Val Ala Leu Pro Asn Glu 100 105 110
Arg Arg His Leu Glu His Gin Gin His Ala Lys Glu His Gly Gly His
115 120 125
(2) INFORMATION FOR SEQ ID NO: 98: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 90 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..90 (D) OTHER INFORMATION: / Ceres Seq. ID 1021565 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 98: Met Ala Leu Arg Arg Val Tyr Ser Glu He Arg Gly Lys Lys Val Thr 1 5 10 15
Glu Leu Pro Gly Tyr He Lys Ser Thr Phe Ser Met Glu Thr Val Lys
20 25 30
Thr Ser Val Lys Arg Gly Leu Asp Asn Tyr Asn Glu Lys Tyr He Gin
35 40 45
Thr Ser Ser Val Asp Pro He Leu His He Cys Phe Tyr Gly Met Ala
50 55 60
Phe Ser Tyr Leu Val Ala Leu Pro Asn Glu Arg Arg His Leu Glu His 65 70 75 80
Gin Gin His Ala Lys Glu His Gly Gly His
85 90
(2) INFORMATION FOR SEQ ID NO: 99: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 586 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..586
(D) OTHER INFORMATION: / Ceres Seq. ID 102157 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 99: ttgcctaaat cattttaaag actgtataga ggaaaacaaa actgcaaaaa caaaaataaa 60 aaaaacatcg cacaagaaaa taaaagattt gtagaatcaa ctaagaaaat ggctagcact 120 atgatgacta cattgcctca gttcaatggt cttcgagcca ccaaaatctc tgcagctcct 180 gtacaaggcc tggcaagtgt tcagcccatg agacgcaagg gaaatggagc tttgggtgca 240 aagtgtgact tcatcggttc atcaacaaat ctgataatgg taacgtcgac gaccctgatg 300 ttgttcgcgg ggagattcgg acttgcgcca tcagccaata ggaaggcgac agctggactt 360 aggttggagg cacgtgactc aggtctacaa acgggtgacc cggccgggtt cacgcttgcg 420 gacactttgg cttgtggcac cgttggtcat atcatcggtg taggagttgt ccttggcctt 480 aaaaacattg gtgctatttg aagttcctaa agctctttta tttgtatttg taaaatttgt 540 agatttttat aacaatattc tcatgcacct gaacgagatc taatgc (2) INFORMATION FOR SEQ ID NO: 100:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 130 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..130
(D) OTHER INFORMATION: / Ceres Seq. ID 1021577
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 100:
Met Ala Ser Thr Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg
1 5 10 15
Ala Thr Lys He Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin
20 25 30
Pro Met Arg Arg Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe
35 40 45
He Gly Ser Ser Thr Asn Leu He Met Val Thr Ser Thr Thr Leu Met
50 55 60
Leu Phe Ala Gly Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala 65 70 75 80
Thr Ala Gly Leu Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly
85 90 95
Asp Pro Ala Gly Phe Thr Leu Ala Asp Thr Leu Ala Cys Gly Thr Val 100 105 110 Gly His He He Gly Val Gly Val Val Leu Gly Leu Lys Asn He Gly
115 120 125
Ala He 130 (2) INFORMATION FOR SEQ ID NO: 101: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 126 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..126 (D) OTHER INFORMATION: / Ceres Seq. ID 1021578
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 101: Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg Ala Thr Lys He 1 5 10 15
Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin Pro Met Arg Arg 20 25 30
Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe He Gly Ser Ser
35 40 45
Thr Asn Leu He Met Val Thr Ser Thr Thr Leu Met Leu Phe Ala Gly 50 55 60 Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala Thr Ala Gly Leu 65 70 75 80
Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly Asp Pro Ala Gly
85 90 95
Phe Thr Leu Ala Asp Thr Leu Ala Cys Gly Thr Val Gly His He He 100 105 110
Gly Val Gly Val Val Leu Gly Leu Lys Asn He Gly Ala He
115 120 125
(2) INFORMATION FOR SEQ ID NO: 102: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 125 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..125
(D) OTHER INFORMATION: / Ceres Seq. ID 1021579 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 102: Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg Ala Thr Lys He Ser 1 5 10 15
Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin Pro Met Arg Arg Lys
20 25 30
Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe He Gly Ser Ser Thr 35 40 45
Asn Leu He Met Val Thr Ser Thr Thr Leu Met Leu Phe Ala Gly Arg
50 55 60
Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala Thr Ala Gly Leu Arg 65 70 75 80 Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly Asp Pro Ala Gly Phe
85 90 95
Thr Leu Ala Asp Thr Leu Ala Cys Gly Thr Val Gly His He He Gly
100 105 110
Val Gly Val Val Leu Gly Leu Lys Asn He Gly Ala He 115 120 125
(2) INFORMATION FOR SEQ ID NO: 103: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 801 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic)
(ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..801
(D) OTHER INFORMATION: / Ceres Seq. ID 1021927 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 103: atttttctct cagaatccat aaaaagagag agagataaat aaagagaaaa ctgaagaagc 60 tagaagatgg agaaaagtaa tgatcatgac aaggctagcc acggcggctc cggtggtggt 120 gccacggaga agtgggagga gactagcctc ggaatccgaa ctgccgagac aatgctccgg 180 ttagctccgg tgggtctttg tgttgcagcg cttgttgtca tgcttaagga ctctgagact 240 aatgagttcg gttcaatttc ttactccaat ctcacagcct ttaggtactt ggtgcacgca 300 aatggaatat gtgcaggcta ctctcttcta tcagcagcca ttgcagcgat gcctcgttct 360 tcttcgacaa tgcctcgtgt ttggaccttc ttttgtctcg accagcttct gacctacctg 420 gttcttgctg ctggagctgt atcagctgag gttctatact tggcttacaa tggagactca 480 gccattactt ggagcgatgc atgtagctcc tacggcggtt tctgtcatag agccactgct 540 tctgttataa tcacattctt tgtggtttgt ttctacatcg ttctctctct aatctcctct 600 tataagctct ttactcgctt tgatcctcct tccattgttg actccgccaa gaatctcgaa 660 gtcgctgtct tcggaagtta gatcctccat ttgctcttca agtacatcta gtttgtcatg 720 tttcaaatgt tgtgtgtttt taactttggt caagagaaag aatgcttatg tatttcctct 780 tgtttcattg cttttcttcc t (2) INFORMATION FOR SEQ ID NO: 104:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 204 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..204 (D) OTHER INFORMATION: / Ceres Seq. ID 1021928
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 104:
Met Glu Lys Ser Asn Asp His Asp Lys Ala Ser His Gly Gly Ser Gly 1 5 10 15
Gly Gly Ala Thr Glu Lys Trp Glu Glu Thr Ser Leu Gly He Arg Thr
20 25 30
Ala Glu Thr Met Leu Arg Leu Ala Pro Val Gly Leu Cys Val Ala Ala
35 40 45
Leu Val Val Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He
50 55 60
Ser Tyr Ser Asn Leu Thr Ala Phe Arg Tyr Leu Val His Ala Asn Gly 65 70 75 80
He Cys Ala Gly Tyr Ser Leu Leu Ser Ala Ala He Ala Ala Met Pro
85 90 95
Arg Ser Ser Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp
100 105 110
Gin Leu Leu Thr Tyr Leu Val Leu Ala Ala Gly Ala Val Ser Ala Glu
115 120 125
Val Leu Tyr Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp
130 135 140
Ala Cys Ser Ser Tyr Gly Gly Phe Cys His Arg Ala Thr Ala Ser Val 145 150 155 160
He He Thr Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He
165 170 175
Ser Ser Tyr Lys Leu Phe Thr Arg Phe Asp Pro Pro Ser He Val Asp
180 185 190
Ser Ala Lys Asn Leu Glu Val Ala Val Phe Gly Ser 195 200 (2) INFORMATION FOR SEQ ID NO: 105: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 169 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..169
(D) OTHER INFORMATION: / Ceres Seq. ID 1021929 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 105: Met Leu Arg Leu Ala Pro Val Gly Leu Cys Val Ala Ala Leu Val Val 1 5 10 15 Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He Ser Tyr Ser 20 25 30
Asn Leu Thr Ala Phe Arg Tyr Leu Val His Ala Asn Gly He Cys Ala
35 40 45
Gly Tyr Ser Leu Leu Ser Ala Ala He Ala Ala Met Pro Arg Ser Ser 50 55 60
Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp Gin Leu Leu 65 70 75 80
Thr Tyr Leu Val Leu Ala Ala Gly Ala Val Ser Ala Glu Val Leu Tyr 85 90 95 Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp Ala Cys Ser
100 105 110
Ser Tyr Gly Gly Phe Cys His Arg Ala Thr Ala Ser Val He He Thr
115 120 125
Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He Ser Ser Tyr 130 135 140
Lys Leu Phe Thr Arg Phe Asp Pro Pro Ser He Val Asp Ser Ala Lys 145 150 155 160
Asn Leu Glu Val Ala Val Phe Gly Ser 16 (2) INFORMATION FOR SEQ ID NO: 106: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 153 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..153 (D) OTHER INFORMATION: / Ceres Seq. ID 1021930
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 106: Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He Ser Tyr Ser 1 5 10 15
Asn Leu Thr Ala Phe Arg Tyr Leu Val His Ala Asn Gly He Cys Ala 20 25 30
Gly Tyr Ser Leu Leu Ser Ala Ala He Ala Ala Met Pro Arg Ser Ser
35 40 45
Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp Gin Leu Leu 50 55 60 Thr Tyr Leu Val Leu Ala Ala Gly Ala Val Ser Ala Glu Val Leu Tyr 65 70 75 80
Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp Ala Cys Ser
85 90 95
Ser Tyr Gly Gly Phe Cys His Arg Ala Thr Ala Ser Val He He Thr 100 105 110
Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He Ser Ser Tyr 115 120 125 Lys Leu Phe Thr Arg Phe Asp Pro Pro Ser He Val Asp Ser Ala Lys
130 135 140
Asn Leu Glu Val Ala Val Phe Gly Ser 145 150
(2) INFORMATION FOR SEQ ID NO: 107: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 602 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..602
(D) OTHER INFORMATION: / Ceres Seq. ID 1021945 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 107: atcgagcgat ggatttggca gaactgtggg cgattttcgg acccggattc tccggcgccg 60 ttttcggaac cgggtggtgg ggtcgacgcc gtcgtttgca gttccatcca agttcccttc 120 gtccattacc ttcccggcat attcgcttct ctcggagctt tgatgttcaa ttgcgtcaga 180 aaagaagaca ttgattactc tccttacgac gaaggcgagt ggagattgaa gctgtggctt 240 ttcatagcgt atgtcgtagc atttgtttcc ttagctgctt ctgttggctt gctgattcaa 300 gattcggttg tgaagactgg gccttcaact tggactggtg tggctggtgt ctttcaatgt 360 gtatttgtat tgataagtgg gctaatgtat tggacatcgc actcagagta gcgcacaggc 420 acatacttca tctccgactc agattcatac tgtgacaact tacaagttcc tctcgtttct 480 ctactatgta aattcctgtg tcttgtcttg tcaccttggc attgtgtgcg agattcctct 540 gttgcatcag tgtgtgtttc tgttaaaact ttgtgtgaat gttattgaaa atactccaaa 600 cc
(2) INFORMATION FOR SEQ ID NO: 108: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 136 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..136 (D) OTHER INFORMATION: / Ceres Seq. ID 1021946
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 108: He Glu Arg Trp He Trp Gin Asn Cys Gly Arg Phe Ser Asp Pro Asp 1 5 10 15
Ser Pro Ala Pro Phe Ser Glu Pro Gly Gly Gly Val Asp Ala Val Val
20 25 30
Cys Ser Ser He Gin Val Pro Phe Val His Tyr Leu Pro Gly He Phe
35 40 45
Ala Ser Leu Gly Ala Leu Met Phe Asn Cys Val Arg Lys Glu Asp He
50 55 60
Asp Tyr Ser Pro Tyr Asp Glu Gly Glu Trp Arg Leu Lys Leu Trp Leu
65 70 75 .0
Phe He Ala Tyr Val Val Ala Phe Val Ser Leu Ala Ala Ser Val Gly
85 90 95
Leu Leu He Gin Asp Ser Val Val Lys Thr Gly Pro Ser Thr Trp Thr
100 105 110
Gly Val Ala Gly Val Phe Gin Cys Val Phe Val Leu He Ser Gly Leu
115 120 125
Met Tyr Trp Thr Ser His Ser Glu
130 135
(2) INFORMATION FOR SEQ ID NO: 109: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 82 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..82
(D) OTHER INFORMATION: / Ceres Seq. ID 1021947 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 109: Met Phe Asn Cys Val Arg Lys Glu Asp He Asp Tyr Ser Pro Tyr Asp 1 5 10 15
Glu Gly Glu Trp Arg Leu Lys Leu Trp Leu Phe He Ala Tyr Val Val
20 25 30
Ala Phe Val Ser Leu Ala Ala Ser Val Gly Leu Leu He Gin Asp Ser
35 40 45
Val Val Lys Thr Gly Pro Ser Thr Trp Thr Gly Val Ala Gly Val Phe
50 55 60
Gin Cys Val Phe Val Leu He Ser Gly Leu Met Tyr Trp Thr Ser His 65 70 75 80
Ser Glu
(2) INFORMATION FOR SEQ ID NO: 110: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 693 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic
(ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..693
(D) OTHER INFORMATION: / Ceres Seq. ID 1022170 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 110: gagtcgctct tctttccttc cgccattttt ttctttctag g^tgcagagt taaaggagaa 60 ggttttcaat tagggttttg tagagagaaa gatgagccga ag ttgggaa taccggtgaa 120 gcttcttcac gaggcctcag gtcatatcgt gacggtggag ctaa<_.gagcg gcgagcttta 180 cagaggaagt atgattgagt gtgaggataa ctggaactgt cagctcgagg atattactta 240 taccgccaag gatggtaagg tatcacagct tgagcatgtc ttcattcgag gcagtaaagt 300 caggtttatg gtcataccag acattctcaa acatgctcca atgttcaagc ggttagatgc 360 tagaatcaag ggaaagagct catcactggg tgttggcaga ggtagagctg caatgcgagg 420 gaaaccggct gccgggcccg ggcgtggaac tggaggaagg ggagcggtac cacctgtgag 480 gagatgattg attttacgct caacatgtaa gctttgattc tgggatagtc tttctgtgat 540 atccaggtga aagccgcctt tcttggttct gtcattaatg ctttagagaa cactgtaaaa 600 ccaaacaaga gagagatata tccagatgca ctagtagttc tgtattttgg gttaccaaga 660 tgtttgaatc attgacaagt tttcgttgtg ate (2) INFORMATION FOR SEQ ID NO: 111: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 131 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..131
(D) OTHER INFORMATION: / Ceres Seq. ID 1022171 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 111: Met Ser Arg Ser Leu Gly He Pro Val Lys Leu Leu His Glu Ala Ser 1 5 10 15
Gly His He Val Thr Val Glu Leu Lys Ser Gly Glu Leu Tyr Arg Gly
20 25 30
Ser Met He Glu Cys Glu Asp Asn Trp Asn Cys Gin Leu Glu Asp He
35 40 45
Thr Tyr Thr Ala Lys Asp Gly Lys Val Ser Gin Leu Glu His Val Phe 50 55 60
He Arg Gly Ser Lys Val Arg Phe Met Val He Pro Asp He Leu Lys 65 70 75 80
His Ala Pro Met Phe Lys Arg Leu Asp Ala Arg He Lys Gly Lys Ser 85 90 95
Ser Ser Leu Gly Val Gly Arg Gly Arg Ala Ala Met Arg Gly Lys Pro
100 105 110
Ala Ala Gly Pro Gly Arg Gly Thr Gly Gly Arg Gly Ala Val Pro Pro 115 120 125 Val Arg Arg 130 (2) INFORMATION FOR SEQ ID NO: 112: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 98 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..98
(D) OTHER INFORMATION: / Ceres Seq. ID 1022172 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 112: Met He Glu Cys Glu Asp Asn Trp Asn Cys Gin Leu Glu Asp He Thr 1 5 10 15
Tyr Thr Ala Lys Asp Gly Lys Val Ser Gin Leu Glu His Val Phe He
20 25 30
Arg Gly Ser Lys Val Arg Phe Met Val He Pro Asp He Leu Lys His 35 40 45 Ala Pro Met Phe Lys Arg Leu Asp Ala Arg He Lys Gly Lys Ser Ser 50 55 60
Ser Leu Gly Val Gly Arg Gly Arg Ala Ala Met Arg Gly Lys Pro Ala 65 70 75 80
Ala Gly Pro Gly Arg Gly Thr Gly Gly Arg Gly Ala Val Pro Pro Val 85 90 95
Arg Arg
(2) INFORMATION FOR SEQ ID NO: 113: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 65 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1022173 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 113: Glu Ser Leu Phe Phe Pro Ser Ala He Phe Phe Phe Leu Gly Cys Arg 1 5 10 15
Val Lys Gly Glu Gly Phe Gin Leu Gly Phe Cys Arg Glu Lys Asp Glu
20 25 30
Pro Lys Phe Gly Asn Thr Gly Glu Ala Ser Ser Arg Gly Leu Arg Ser 35 40 45
Tyr Arg Asp Gly Gly Ala Lys Glu Arg Arg Ala Leu Gin Arg Lys Tyr
50 55 60
Asp 65 (2) INFORMATION FOR SEQ ID NO: 114: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 706 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..706
(D) OTHER INFORMATION: / Ceres Seq. ID 1022554
(xi) SEQUFNCE DESCRIPTION: SEQ ID NO: 114: agaccaaaaa agcggttggt gtaagatccc aaactcacag attcccaaat aatagtaata 60 ctcttcctct tctcaactct caccagtcac cagcagatca tcggagatgg gcggagacgg 120 aaaagttttc accttgtccg aggttcctca gcacagtagc gccaaggatt gttggatcgt 180 catcgacggc aaggtttatg atgtgacaaa gttcttggat gatcatcctg gtggtgatga 240 ggttatcttg acttctacag ggaaagatgc gaccgatgat ttcgaggatg tgggacatag 300 ttcgactgcg aaagccatgc tagatgagta ctatgtgggt gatattgaca cagctactgt 360 gccggttaaa gctaagtttg tgcctcctac gtcgacgaaa gccgtggcta ctcaggataa 420 gagctcggat tttgttatta agctccttca gttccttgtt ccacttctaa tcttaggctt 480 ggctttcggc attcggtact acactaagac caaggctcct tcttcttgaa agattgaatt 540 gtggcctaag tgaattgctt gtgtacgacg tggttaaact ctgtctctac ctctgtttgt 600 cttgtaagac atcattatat tctctattgc aatcaactga tagacctttg atttttaagc 660 catctacctt tgttgtctta tatcaatcaa atccatttac aatatc (2) INFORMATION FOR SEQ ID NO: 115: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 140 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..140 (D) OTHER INFORMATION: / Ceres Seq. ID 1022555
(xi) SEQUENCE DESCRIPTION. SEQ ID NO: 115:
Met Gly Gly Asp Gly Lys Val Phe Thr Leu Ser Glu Val Ser Gin His
1 5 10 15
Ser Ser Ala Lys Asp Cys Trp He Val He Asp Gly Lys Val Tyr Asp 20 25 30
Val Thr Lys Phe Leu Asp Asp His Pro Gly Gly Asp Glu Val He Leu 35 40 45
Thr Ser Thr Gly Lys Asp Ala Thr Asp Asp Phe Glu Asp Val Gly His 50 55 60
Ser Ser Thr Ala Lys Ala Met Leu Asp Glu Tyr Tyr Val Gly Asp He 65 70 75 80
Asp Thr Ala Thr Val Pro Val Lys Ala Lys Phe Val Pro Pro Thr Ser 85 90 95
Thr Lys Ala Val Ala Thr Gin Asp Lys Ser Ser Asp Phe Val He Lys 100 105 110
Leu Leu Gin Phe Leu Val Pro Leu Leu He Leu Gly Leu Ala Phe Gly 115 120 125
He Arg Tyr Tyr Thr Lys Thr Lys Ala Pro Ser Ser 130 135 140
(2) INFORMATION FOR SEQ ID NO:H6:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 70 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..70
(D) OTHER INFORMATION: / Ceres Seq. ID 1022556 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 116: Met Leu Asp Glu Tyr Tyr Val Gly Asp He Asp Thr Ala Thr Val Pro 1 5 10 15
Val Lys Ala Lys Phe Val Pro Pro Thr Ser Thr Lys Ala Val Ala Thr 20 25 30
Gin Asp Lys Ser Ser Asp Phe Val He Lys Leu Leu Gin Phe Leu Val
35 40 45
Pro Leu Leu He Leu Gly Leu Ala Phe Gly He Arg Tyr Tyr Thr Lys 50 55 60 Thr Lys Ala Pro Ser Ser 65 70
(2) INFORMATION FOR SEQ ID NO: 117: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 722 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..722
(D) OTHER INFORMATION: / Ceres Seq. ID 1022594 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 117: aacgtcatca ttctgacttt tctcaaagaa gagaaatcaa atcaccaagt catcggagcg 60 atcacagaga agaagaaaac catggcggaa gaagagaaaa gcgtgatgaa gcaagtgatg 120 gtggcgattg atgaaagcga atgtagtaaa cgcgctcttc aatggacgct cgtgtatctc 180 aaagatagcc tcgccgattc cgacatcatc ctcttcactg ctcaacctca tcttgatctc 240 agctgcgtct atgcttcctc ttatggcgcc gctccgattg agcttataaa ctcattgcaa 300 gagagtcata agaacgctgg attgaatcgt cttgatgaag gaaccaaaat ttgtgctgag 360 actggggtta ctccaagaaa ggtgttggaa tttggaaatc ctaaagaagc gatatgtgaa 420 gctgctgaga agcttggtgt tgatatgctt gtggttggaa gccatggtaa aggagcatta 480 caaaggactt tccttggaag tgttagcaat tactgtgtta acaatgctaa gtgcccagtt 540 cttgtggtga gaacaaaagc ttgaagacct ctcctcatga aagagttcga caaccctggc 600 ttgatgtgtg tgtgttgtaa acatattgat aataatgctc tgcttggtta ctattgtttg 660 aagaaacttt gtgagtaaac ataatttatt ttgtttgata atgaaagagc attgccgtgt 720 tc
(2) INFORMATION FOR SEQ ID NO: 118: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 187 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..187
(D) OTHER INFORMATION: / Ceres Seq. ID 1022595 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 118:
Asn Val He He Leu Thr Phe Leu Lys Glu Glu Lys Ser Asn His Gin 1 5 10 15
Val He Gly Ala He Thr Glu Lys Lys Lys Thr Met Ala Glu Glu Glu
20 25 30
Lys Ser Val Met Lys Gin Val Met Val Ala He Asp Glu Ser Glu Cys 35 40 45 Ser Lys Arg Ala Leu Gin Trp Thr Leu Val Tyr Leu Lys Asp Ser Leu 50 55 60
Ala Asp Ser Asp He He Leu Phe Thr Ala Gin Pro His Leu Asp Leu
65 70 75 80
Ser Cys Val Tyr Ala Ser Ser Tyr Gly Ala Ala Pro He Glu Leu He 85 90 95
Asn Ser Leu Gin Glu Ser His Lys Asn Ala Gly Leu Asn Arg Leu Asp 100 105 110 Glu Gly Thr Lys He Cys Ala Glu Thr Gly Val Thr Pro Arg Lys Val
115 120 125
Leu Glu Phe Gly Asn Pro Lys Glu Ala He Cys Glu Ala Ala Glu Lys
130 135 140 Leu Gly Val Asp Met Leu Val Val Gly Ser His Gly Lys Gly Ala Leu
145 150 155 160
Gin Arg Thr Phe Leu Gly Ser Val Ser Asn Tyr Cys Val Asn Asn Ala
165 170 175
Lys Cys Pro Val Leu Val Val Arg Thr Lys Ala 180 185
(2) INFORMATION FOR SEQ ID NO: 119: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 160 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..160
(D) OTHER INFORMATION: / Ceres Seq. ID 1022596 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 119: Met Ala Glu Glu Glu Lys Ser Val Met Lys Gin Val Met Val Ala He 1 5 10 15 Asp Glu Ser Glu Cys Ser Lys Arg Ala Leu Gin Trp Thr Leu Val Tyr 20 25 30
Leu Lys Asp Ser Leu Ala Asp Ser Asp He He Leu Phe Thr Ala Gin
35 40 45
Pro His Leu Asp Leu Ser Cys Val Tyr Ala Ser Ser Tyr Gly Ala Ala 50 55 60
Pro He Glu Leu He Asn Ser Leu Gin Glu Ser His Lys Asn Ala Gly 65 70 75 80
Leu Asn Arg Leu Asp Glu Gly Thr Lys He Cys Ala Glu Thr Gly Val 85 90 95 Thr Pro Arg Lys Val Leu Glu Phe Gly Asn Pro Lys Glu Ala He Cys 100 105 110
Glu Ala Ala Glu Lys Leu Gly Val Asp Met Leu Val Val Gly Ser His
115 120 125
Gly Lys Gly Ala Leu Gin Arg Thr Phe Leu Gly Ser Val Ser Asn Tyr 130 135 140
Cys Val Asn Asn Ala Lys Cys Pro Val Leu Val Val Arg Thr Lys Ala 145 150 155 160
(2) INFORMATION FOR SEQ ID NO: 120: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 152 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..152
(D) OTHER INFORMATION: / Ceres Seq. ID 1022597 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 120: Met Lys Gin Val Met Val Ala He Asp Glu Ser Glu Cys Ser Lys Arg 1 5 10 15
Ala Leu Gin Trp Thr Leu Val Tyr Leu Lys Asp Ser Leu Ala Asp Ser
20 25 30
Asp He He Leu Phe Thr Ala Gin Pro His Leu Asp Leu Ser Cys Val 35 40 45
Tyr Ala Ser Ser Tyr Gly Ala Ala Pro He Glu Leu He Asn Ser Leu 50 55 60 Gin Glu Ser His Lys Asn Ala Gly Leu Asn Arg Leu Asp Glu Gly Thr 65 70 75 80
Lys He Cys Ala Glu Thr Gly Val Thr Pro Arg Lys Val Leu Glu Phe
85 90 95
Gly Asn Pro Lys Glu Ala He Cys Glu Ala Ala Glu Lys Leu Gly Val
100 105 110
Asp Met Leu Val Val Gly Ser His Gly Lys Gly Ala Leu Gin Arg Thr
115 120 125
Phe Leu Gly Ser Val Ser Asn Tyr Cys Val Asn Asn Ala Lys Cys Pro
130 135 140
Val Leu Val Val Arg Thr Lys Ala
145 150 2) INFORMATION FOR SEQ ID NO: 121:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 610 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..610
(D) OTHER INFORMATION: / Ceres Seq. ID 1022621
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 121: aattttgtgt ggtaattaac tggtgagaga gttcaacatc caatctttct ctctctctct 60 atcttttatc tctcacactc ttaaaatgct tcttctatct ccgatctctg cctctcttcc 120 accgtcgttt caccggggta atttgatccg gcgatcaatt aagccgttag gtagggttgt 180 tgcaaaggcc aaggacaaca ccgacactgg tggatttctg gagacggcag ctatagccgg 240 tggtttagtg tcgacgccgg ttattggatg gtcactctac actttgaaga ccacgggatg 300 tggcttacct cccggaccgg ccggtttaat cggagcgttg gaaggtgtga gctacttggt 360 ggtggttggc atcgtgggct ggtctttgta cactaaaaca aaaactgggt caggtctgcc 420 aaatgggcca tttggtttgt tgggtgcggt cσagggttta tcgtatctgt cggttctagc 480 cattcttgtg gtgtttggta ttcagttctt ggataatggg tcggttccag gtccacttcc 540 tagtgaccag tgttttggtt aaccacgtgt aatgtcgtat aaataaagtg tcaaattaat 600 aattgctttc
(2) INFORMATION FOR SEQ ID NO: 122: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 158 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..158 (D) OTHER INFORMATION: / Ceres Seq. ID 1022622
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 122:
Met Leu Leu Leu Ser Pro He Ser Ala Ser Leu Pro Pro Ser Phe His
1 5 10 15
Arg Gly Asn Leu He Arg Arg Ser He Lys Pro Leu Gly Arg Val Val 20 25 30
Ala Lys Ala Lys Asp Asn Thr Asp Thr Gly Gly Phe Leu Glu Thr Ala 35 40 45
Ala He Ala Gly Gly Leu Val Ser Thr Pro Val He Gly Trp Ser Leu 50 55 60
Tyr Thr Leu Lys Thr Thr Gly Cys Gly Leu Pro Pro Gly Pro Ala Gly
65 70 75 80
Leu He Gly Ala Leu Glu Gly Val Ser Tyr Leu Val Val Val Gly He 85 90 95
Val Gly Trp Ser Leu Tyr Thr Lys Thr Lys Thr Gly Ser Gly Leu Pro 100 105 110
Asn Gly Pro Phe Gly Leu Leu Gly Ala Val Glu Gly Leu Ser Tyr Leu 115 120 125
Ser Val Leu Ala He Leu Val Val Phe Gly He Gin Phe Leu Asp Asn
130 135 140
Gly Ser Val Pro Gly Pro Leu Pro Ser Asp Gin Cys Phe Gly 145 150 155
(2) INFORMATION FOR SEQ ID NO: 123: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 872 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..872
(D) OTHER INFORMATION: / Ceres Seq. ID 1024375 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:123: atcgaacatt aaaacctgat tttactgaaa ctgtgctgcg aaggagaagc cgcaaaccat 60 tttttgtcaa tctagggttc ttcttcgtac ttgcagattt cgcctccgtt ttcactacga 120 tctgtgaaga tgttctccgc tcagaacaag atcaataagg acaagaatgc tgagccaaca 180 gaatgcgagg agcaagttgc tcaggctttg tttgatttgg agaacactaa ccaggagttg 240 aaaagcgagt tgaaagatct ctacatcaac caagctgttc acatggatat ctctggaaac 300 cgcaaagctg ttgtgattta cgttccattc agattgagga aagctttccg caagattcat 360 ccccgtctcg tcagagagct tgagaagaag ttcagtggaa aggatgttat ctttgttacc 420 acaagaagga tcatgcgtcc ccccaagaag ggtgctgctg ttcagaggcc acgtaacaga 480 actcttacct cagttcatga agctatgctt gaagatgttg ctttccccgc tgagattgtt 540 ggaaagcgta ctcgctaccg tcttgatggt tccaagatca tgaaggtctt tttggatgcc 600 aaggaaaaga acaacacaga gtacaagctc gagactatgg tcggtgtgta ccgtaaactt 660 actggcaaag atgttgtttt tgagtaccca gtcgaagctt gaaagaagat gatgaagaac 720 catcaggata gtgaaagaga gcttttgttt atgttttgtg gtatttagga tgaaggaaac 780 tctcttgatt cagttccttg ttcacaatct ttaatgttct atttacaatg actacttttt 840 gtgtttttca attttgaaac ctctatgatt tc (2) INFORMATION FOR SEQ ID NO: 124: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 190 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..190
(D) OTHER INFORMATION: / Ceres Seq. ID 1024376 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 124: Met Phe Ser Ala Gin Asn Lys He Asn Lys Asp Lys Asn Ala Glu Pro 1 5 10 15
Thr Glu Cys Glu Glu Gin Val Ala Gin Ala Leu Phe Asp Leu Glu Asn
20 25 30
Thr Asn Gin Glu Leu Lys Ser Glu Leu Lys Asp Leu Tyr He Asn Gin 35 40 45
Ala Val His Met Asp He Ser Gly Asn Arg Lys Ala Val Val He Tyr
50 55 60
Val Pro Phe Arg Leu Arg Lys Ala Phe Arg Lys He His Pro Arg Leu 65 70 75 80 Val Arg Glu Leu Glu Lys Lys Phe Ser Gly Lys Asp Val He Phe Val
85 90 95
Thr Thr Arg Arg He Met Arg Pro Pro Lys Lys Gly Ala Ala Val Gin
100 105 110
Arg Pro Arg Asn Arg Thr Leu Thr Ser Val His Glu Ala Met Leu Glu 115 120 125
Asp Val Ala Phe Pro Ala Glu He Val Gly Lys Arg Thr Arg Tyr Arg 130 135 140 Leu Asp Gly Ser Lys He Met Lys Val Phe Leu Asp Ala Lys Glu Lys 145 150 155 160
Asn Asn Thr Glu Tyr Lys Leu Glu Thr Met Val Gly Val Tyr Arg Lys
165 170 175
Leu Thr Gly Lys Asp Val Val Phe Glu Tyr Pro Val Glu Ala 180 185 190
(2) INFORMATION FOR SEQ ID NO: 125:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 139 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY peptide
(B) LOCATION 1..139
(D) OTHER INFORMATION: / Ceres Seq. ID 1024377
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 125:
Met Asp He Ser Gly Asn Arg Lys Ala Val Val He Tyr Val Pro Phe
1 5 10 15
Arg Leu Arg Lys Ala Phe Arg Lys He His Pro Arg Leu Val Arg Glu
20 25 30
Leu Glu Lys Lys Phe Ser Gly Lys Asp Val He Phe Val Thr Thr Arg
35 40 45
Arg He Met Arg Pro Pro Lys Lys Gly Ala Ala Val Gin Arg Pro Arg
50 55 60
Asn Arg Thr Leu Thr Ser Val His Glu Ala Met Leu Glu Asp Val Ala 65 70 75 80
Phe Pro Ala Glu He Val Gly Lys Arg Thr Arg Tyr Arg Leu Asp Gly
85 90 95
Ser Lys He Met Lys Val Phe Leu Asp Ala Lys Glu Lys Asn Asn Thr
100 105 110
Glu Tyr Lys Leu Glu Thr Met Val Gly Val Tyr Arg Lys Leu Thr Gly
115 120 125
Lys Asp Val Val Phe Glu Tyr Pro Val Glu Ala 130 135
(2) INFORMATION FOR SEQ ID NO: 126:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 545 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..545 (D) OTHER INFORMATION: / Ceres Seq. ID 1024535
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 126: aaaaattgtt aagttcgtgt ccgcgagatc agagtttgtg tccggttata cgattcgtcg 60 gtaccaaaac cctccgagaa gtgtttcagg tgggaaggta tctctgtcta cacgatgtcc 120 ggcgaggaag aagccaccgt gagggagcca ctagatctga ttaggctgag tctcgacgag 180 agaatctatg tcaagctccg gtcagaccgc gaacttcgcg gcaagcttca cgcgtttgat 240 cagcatttga atatgattct gggtgatgtt gaagaaacta tcactacagt agaaatcgat 300 gacgagacat atgaagagat tgttcggact acaaagcgga cgattgagtt tctattcgtg 360 agaggagatg gagtgatatt ggtgtctcca ccgctgagga cagcagcctg agttcaaact 420 caaatctttt gtgtcctctt ttcgtaaggg gaatttgtga ctattcttgt atttagtcac 480 ttcttgtctt aactaaaaca agcttgaaga agctagtttg cttaaatttc caatgctttt 540 cagac
(2) INFORMATION FOR SEQ ID NO: 127: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 98 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..98
(D) OTHER INFORMATION: / Ceres Seq. ID 1024536 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 127: Met Ser Gly Glu Glu Glu Ala Thr Val Arg Glu Pro Leu Asp Leu He 1 5 10 15
Arg Leu Ser Leu Asp Glu Arg He Tyr Val Lys Leu Arg Ser Asp Arg
20 25 30
Glu Leu Arg Gly Lys Leu His Ala Phe Asp Gin His Leu Asn Met He 35 40 45 Leu Gly Asp Val Glu Glu Thr He Thr Thr Val Glu He Asp Asp Glu 50 55 60
Thr Tyr Glu Glu He Val Arg Thr Thr Lys Arg Thr He Glu Phe Leu 65 70 75 80
Phe Val Arg Gly Asp Gly Val He Leu Val Ser Pro Pro Leu Arg Thr 85 90 95
Ala Ala
(2) INFORMATION FOR SEQ ID NO: 128: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 53 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..53
(D) OTHER INFORMATION: / Ceres Seq. ID 1024537 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 128: Lys Leu Leu Ser Ser Cys Pro Arg Asp Gin Ser Leu Cys Pro Val He 1 5 10 15
Arg Phe Val Gly Thr Lys Thr Leu Arg Glu Val Phe Gin Val Gly Arg
20 25 30
Tyr Leu Cys Leu His Asp Val Arg Arg Gly Arg Ser His Arg Glu Gly 35 40 45
Ala Thr Arg Ser Asp
50 (2) INFORMATION FOR SEQ ID NO: 129: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 52 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..52
(D) OTHER INFORMATION: / Ceres Seq. ID 1024538 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 129: Met He Leu Gly Asp Val Glu Glu Thr He Thr Thr Val Glu He Asp 1 5 10 15
Asp Glu Thr Tyr Glu Glu He Val Arg Thr Thr Lys Arg Thr He Glu
20 25 30
Phe Leu Phe Val Arg Gly Asp Gly Val He Leu Val Ser Pro Pro Leu 35 40 45
Arg Thr Ala Ala 50 (2) INFORMATION FOR SEQ ID NO: 130: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 797 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..797
(D) OTHER INFORMATION: / Ceres Seq. ID 1025683
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 130: aacccttaaa ctccgttacc ctaaacctca agccgtcgtc tccaaagttc cccctcagag 60 acgaaaaaat gaagaccatt ttgtcctcgg agactatgga catccccgac ggcgtcgcca 120 ttaaggtaaa cgccaaggtg attgaggtcg aaggtccacg aggtaaactc actcgtgact 180 tcaagcatct gaatctcgat ttccagttga ttaaagacca agtcactgga aaacgtcagc 240 ttaagattga ttcttggttt ggttctcgta agacaagtgc ttcgattaga actgctttaa 300 gccatgttga taatctcatt gctggtgtta ctcaaggttt tctttataga atgagatttg 360 tgtatgctca ttttcctatc aatgcttcta ttgatggtaa caataagagt attgagattc 420 gtaacttcct tggtgagaag aaggtgagga aggttgagat gttggatggt gttaagattg 480 ttcgatctga gaaggttaag gatgagatta ttcttgaggg aaatgatatt gagcttgttt 540 cacggtcttg tgctttgatc aatcagaaat gtcatgtgaa gaagaaggat atcaggaagt 600 ttcttgatgg tatctatgtg agcgagaaag gcaagatcgc agtcgaggaa tgaagttcgc 660 tattgaaagt tctatattag attttatatg gtgaagcagt gatattatcg tagctttttg 720 ttttacatct ttcttatgga tttgtagttt tgtttttcct tttgaatcat tgatgaatgc 780 aaattcatta tccgttc
(2) INFORMATION FOR SEQ ID NO: 131: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 216 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..216
(D) OTHER INFORMATION: / Ceres Seq. ID 1025684 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 131: Pro Leu Asn Ser Val Thr Leu Asn Leu Lys Pro Ser Ser Pro Lys Phe 1 5 10 15
Pro Leu Arg Asp Glu Lys Met Lys Thr He Leu Ser Ser Glu Thr Met
20 25 30
Asp He Pro Asp Gly Val Ala He Lys Val Asn Ala Lys Val He Glu 35 40 45 Val Glu Gly Pro Arg Gly Lys Leu Thr Arg Asp Phe Lys His Leu Asn 50 55 60
Leu Asp Phe Gin Leu He Lys Asp Gin Val Thr Gly Lys Arg Gin Leu 65 70 75 80
Lys He Asp Ser Trp Phe Gly Ser Arg Lys Thr Ser Ala Ser He Arg 85 90 95
Thr Ala Leu Ser His Val Asp Asn Leu He Ala Gly Val Thr Gin Gly
100 105 110
Phe Leu Tyr Arg Met Arg Phe Val Tyr Ala His Phe Pro He Asn Ala 115 120 125 Ser He Asp Gly Asn Asn Lys Ser He Glu He Arg Asn Phe Leu Gly 130 135 140
Glu Lys Lys Val Arg Lys Val Glu Met Leu Asp Gly Val Lys He Val 145 150 155 160
Arg Ser Glu Lys Val Lys Asp Glu He He Leu Glu Gly Asn Asp He 165 170 175
Glu Leu Val Ser Arg Ser Cys Ala Leu He Asn Gin Lys Cys His Val 180 185 190 Lys Lys Lys Asp He Arg Lys Phe Leu Asp Gly He Tyr Val Ser Glu
195 200 205
Lys Gly Lys He Ala Val Glu Glu 210 215 (2) INFORMATION FOR SEQ ID NO: 132: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 194 amino "acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..194 (D) OTHER INFORMATION: / Ceres Seq. ID 1025685
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 132: Met Lys Thr He Leu Ser Ser Glu Thr Met Asp He Pro Asp Gly Val 1 5 10 15
Ala He Lys Val Asn Ala Lys Val He Glu Val Glu Gly Pro Arg Gly 20 25 30
Lys Leu Thr Arg Asp Phe Lys His Leu Asn Leu Asp Phe Gin Leu He
35 40 45
Lys Asp Gin Val Thr Gly Lys Arg Gin Leu Lys He Asp Ser Trp Phe 50 55 60 Gly Ser Arg Lys Thr Ser Ala Ser He Arg Thr Ala Leu Ser His Val 65 70 75 80
Asp Asn Leu He Ala Gly Val Thr Gin Gly Phe Leu Tyr Arg Met Arg
85 90 95
Phe Val Tyr Ala His Phe Pro He Asn Ala Ser He Asp Gly Asn Asn 100 105 110
Lys Ser He Glu He Arg Asn Phe Leu Gly Glu Lys Lys Val Arg Lys
115 120 125
Val Glu Met Leu Asp Gly Val Lys He Val Arg Ser Glu Lys Val Lys
130 135 140 Asp Glu He He Leu Glu Gly Asn Asp He Glu Leu Val Ser Arg Ser
145 150 155 160
Cys Ala Leu He Asn Gin Lys Cys His Val Lys Lys Lys Asp He Arg
165 170 175
Lys Phe Leu Asp Gly He Tyr Val Ser Glu Lys Gly Lys He Ala Val 180 185 190
Glu Glu
(2) INFORMATION FOR SEQ ID NO: 133: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 185 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..185
(D) OTHER INFORMATION: / Ceres Seq. ID 1025686 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 133: Met Asp He Pro Asp Gly Val Ala He Lys Val Asn Ala Lys Val He 1 5 10 15
Glu Val Glu Gly Pro Arg Gly Lys Leu Thr Arg Asp Phe Lys His Leu
20 25 30
Asn Leu Asp Phe Gin Leu He Lys Asp Gin Val Thr Gly Lys Arg Gin 35 40 45
Leu Lys He Asp Ser Trp Phe Gly Ser Arg Lys Thr Ser Ala Ser He 50 55 60 Arg Thr Ala Leu Ser His Val Asp Asn Leu He Ala Gly Val Thr Gin 65 70 75 80
Gly Phe Leu Tyr Arg Met Arg Phe Val Tyr Ala His Phe Pro He Asn
85 90 95
Ala Ser He Asp Gly Asn Asn Lys Ser He Glu He Arg Asn Phe Leu
100 105 110
Gly Glu Lys Lys Val Arg Lys Val Glu Met Leu Asp Gly Val Lys He
115 120 125
Val Arg Ser Glu Lys Val Lys Asp Glu He He Leu Glu Gly Asn Asp
130 135 140
He Glu Leu Val Ser Arg Ser Cys Ala Leu He Asn Gin Lys Cys His 145 150 155 160
Val Lys Lys Lys Asp He Arg Lys Phe Leu Asp Gly He Tyr Val Ser
165 170 175 Glu Lys Gly Lys He Ala Val Glu Glu 180 185
(2) INFORMATION FOR SEQ ID NO: 134:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 555 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..555 (D) OTHER INFORMATION: / Ceres Seq. ID 1027152
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 134: ggttttgtca tcgtgctcct cttctcctcc accgcacaga tccaagacat tttgattaca 60 ctccatcgcc ggcgaaaatg gtgacggaaa agaaaacgaa gaagtctcat gagggtatca 120 acagtaggtt ggctcttgtt atgaagagtg gtaaatacac tcttggttac aagtctgttc 180 tcaaatccct ccgtggctcc aaagggaaac tgεttctaat ctccaccaat tgcccaccgt 240 tgagaagatc agagattgag tactacgcaa tgctcgctaa agttggtgtc caccattaca 300 atggaaataa cgttgatttg ggaacagctt gcggaaagta cttccgtgtt tcttgtctga 360 gcattgttga tcctggtgat tctgacatta tcaagtcaat tcctggtgac cagtgataca 420 attttcagat tttatttttc ccagactttt tacccgtctt tgtattcgag tctctcaaaa 480 ttttatgagc aatagacatt gtgtttcttc tttgtcaagt tttcttatat tgaggaccgg 540 aaaagaaatt tcttt
(2) INFORMATION FOR SEQ ID NO: 135: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 137 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..137 (D) OTHER INFORMATION: : / Ceres ; Seq. ID 1027153
(xi) SEQUENCE DESCRIPTION: SEQ . [D NO:135:
Phe Cys His Arg Ala Pro Leu Leu Leu His Arg Thr Asp Pro Arg His
1 5 10 15
Phe Asp Tyr Thr Pro Ser Pro Ala Lys Met Val Thr Glu Lys Lys Thr 20 25 30
Lys Lys Ser His Glu Gly He Asn Ser Arg Leu Ala Leu Val Met Lys 35 40 45
Ser Gly Lys Tyr Thr Leu Gly Tyr Lys Ser Val Leu Lys Ser Leu Arg
50 55 60
Gly Ser Lys Gly Lys Leu He Leu He Ser Thr Asn Cys Pro Pro Leu 65 70 75 80
Arg Arg Ser Glu He Glu Tyr Tyr Ala Met Leu Ala Lys Val Gly Val 85 90 95 His His Tyr Asn Gly Asn Asn Val Asp Leu Gly Thr Ala Cys Gly Lys
100 105 110
Tyr Phe Arg Val Ser Cys Leu Ser He Val Asp Pro Gly Asp Ser Asp 115 120 125 He He Lys Ser He Pro Gly Asp Gin 130 135
(2) INFORMATION FOR SEQ ID NO:136: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 112 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..112
(D) OTHER INFORMATION: / Ceres Seq. ID 1027154 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 136: Met Val Thr Glu Lys Lys Thr Lys Lys Ser His Glu Gly He Asn Ser 1 5 10 15
Arg Leu Ala Leu Val Met Lys Ser Gly Lys Tyr Thr Leu Gly Tyr Lys
20 25 30
Ser Val Leu Lys Ser Leu Arg Gly Ser Lys Gly Lys Leu He Leu He 35 40 45 Ser Thr Asn Cys Pro Pro Leu Arg Arg Ser Glu He Glu Tyr Tyr Ala 50 55 60
Met Leu Ala Lys Val Gly Val His His Tyr Asn Gly Asn Asn Val Asp 65 70 75 80
Leu Gly Thr Ala Cys Gly Lys Tyr Phe Arg Val Ser Cys Leu Ser He 85 90 95
Val Asp Pro Gly Asp Ser Asp He He Lys Ser He Pro Gly Asp Gin
100 105 110
(2) INFORMATION FOR SEQ ID NO: 137: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 91 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..91
(D) OTHER INFORMATION: / Ceres Seq. ID 1027155 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 137: Met Lys Ser Gly Lys Tyr Thr Leu Gly Tyr Lys Ser Val Leu Lys Ser 1 5 10 15
Leu Arg Gly Ser Lys Gly Lys Leu He Leu He Ser Thr Asn Cys Pro
20 25 30
Pro Leu Arg Arg Ser Glu He Glu Tyr Tyr Ala Met Leu Ala Lys Val 35 40 45
Gly Val His His Tyr Asn Gly Asn Asn Val Asp Leu Gly Thr Ala Cys
50 55 60
Gly Lys Tyr Phe Arg Val Ser Cys Leu Ser He Val Asp Pro Gly Asp 65 70 75 80 Ser Asp He He Lys Ser He Pro Gly Asp Gin
85 90
(2) INFORMATION FOR SEQ ID NO: 138: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 653 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear ( ϋ ) MOLECULE TYPE : DNA ( genomic ) ( ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..653
(D) OTHER INFORMATION: / Ceres Seq. ID 102809 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 138: aaataaagtt tttatttatc tatctatcca attggagacg aatcatatcg agcgatggat 60 ttggcagaac tgtgggcgat tttcggaccc ggattctccg gcgccgtttt cggaaccggg 120 tggtggtttt gggtcgacgc cgtcgtttgc agttccatcc aagttccctt cgtccattac 180 cttcccggca tattcgcttc tctcggagct ttgatgttca attgcgtcag aaaagaagac 240 attgattact ctccttacga cgaaggcgag tggagattga agctgtggct tttcatagcg 300 tatgtcgtag catttgtttc cttagctgct tctgttggct tgctgattca agattcggtt 360 gtgaagactg ggccttcaac ttggactggt gtggctggtg tctttcaatg tgtatttgta 420 ttgataagtg ggctaatgta ttggacatcg cactcagagt agcgcacagg cacatacttc 480 atctccgact cagattcata ctgtgacaac ttacaagttc ctctcgtttc tctactatgt 540 aaattcctgt gtcttgtctt gtcaccttgg cattgtgtgc gagattcctc tgttgcatca 600 gtgtgtgttt ctgttaaaac tttgtgtgaa tgttattgaa aatactccaa ate (2) INFORMATION FOR SEQ ID NO: 139:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 135 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..135
(D) OTHER INFORMATION: / Ceres Seq. ID 1028096 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 139: Met Asp Leu Ala Glu Leu Trp Ala He Phe Gly Pro Gly Phe Ser Gly 1 5 10 15
Ala Val Phe Gly Thr Gly Trp Trp Phe Trp Val Asp Ala Val Val Cys
20 25 30
Ser Ser He Gin Val Pro Phe Val His Tyr Leu Pro Gly He Phe Ala
35 40 45
Ser Leu Gly Ala Leu Met Phe Asn Cys Val Arg Lys Glu Asp He Asp
50 55 60
Tyr Ser Pro Tyr Asp Glu Gly Glu Trp Arg Leu Lys Leu Trp Leu Phe 65 70 75 80
He Ala Tyr Val Val Ala Phe Val Ser Leu Ala Ala Ser Val Gly Leu
85 90 95
Leu He Gin Asp Ser Val Val Lys Thr Gly Pro Ser Thr Trp Thr Gly
100 105 110
Val Ala Gly Val Phe Gin Cys Val Phe Val Leu He Ser Gly Leu Met
115 120 125
Tyr Trp Thr Ser His Ser Glu 130 135
(2) INFORMATION FOR SEQ ID NO: 140: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 82 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..82
(D) OTHER INFORMATION: / Ceres Seq. ID 1028097 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 140:
Met Phe Asn Cys Val Arg Lys Glu Asp He Asp Tyr Ser Pro Tyr Asp 1 5 10 15
Glu Gly Glu Trp Arg Leu Lys Leu Trp Leu Phe He Ala Tyr Val Val 20 25 30
Ala Phe Val Ser Leu Ala Ala Ser Val Gly Leu Leu He Gin Asp Ser
35 40 45
Val Val Lys Thr Gly Pro Ser Thr Trp Thr Gly Val Ala Gly Val Phe
50 55 60
Gin Cys Val Phe Val Leu He Ser Gly Leu Met Tyr Trp Thr Ser His 65 70 75 80
Ser Glu
(2) INFORMATION FOR SEQ ID NO: 141: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 80 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..80
( D) OTHER INFORMATION : / Ceres Seq . ID 1028098
(xi) SEQUENCE DESCRIPTION : SEQ ID NO : 141 :
He Lys Phe Leu Phe He Tyr Leu Ser Asn Trp Arg Arg He He Ser
1 5 10 15
Ser Asp Gly Phe Gly Arg Thr Val Gly Asp Phe Arg Thr Arg He Leu
20 25 30
Arg Arg Arg Phe Arg Asn Arg Val Val Val Leu Gly Arg Arg Arg Arg
35 40 45
Leu Gin Phe His Pro Ser Ser Leu Arg Pro Leu Pro Ser Arg His He
50 55 60
Arg Phe Ser Arg Ser Phe Asp Val Gin Leu Arg Gin Lys Arg Arg His
65 7 700 75 80
(2) INFORMATION FOR SEQ ID NO: 142: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 779 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..779
(D) OTHER INFORMATION: / Ceres Seq. ID 1028601 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 142: gtctaaactc taaactctaa agactttgtc atttcgtgaa ccgtcgtcat aactgatcct 60 tccaaagaat ctccaaaatc cctaaacttc gaaaatggca gaaaccgccg agacaatcaa 120 caccacgatc tcatcgccgc caccggaatc cgaaagctcc accactattt ctgcaatgac 180 agatccaaca tctcaagaag cagcctcaaa agacacagat ctgacgaaag aagccgaatc 240 agagaagaaa ccaggaggaa tctctctccg aatctggcca ccgactcaga aaactcgcga 300 cgccgttctg aatcgcctga tcgagacctt atccaccgaa tcaatcctct ctaagagata 360 cggtactctt aaatctgacg atgcaaccac cgtcgcgaaa cttatcgaag aagaggctta 420 tggtgttgct tcgaatgctg tgtcgagtga tgatgatggg attaagattc ttgagcttta 480 ttctaaagag attagtaaga ggatgcttga atctgttaag gctagatcta atgctagtgt 540 tggaaatgga agtgtggagg atgctaatac tgatgctagt gaggtttcta aagatgatgc 600 tggtcctggt tcagaggagg agaagagtga ggcttgagaa atttggtttt acttccttat 660 tataatctgt tgtctcttag ggttttgctg ttcttgtaat gatgatgatg acttgtggat 720 ttggtattat gcatatttga agatgtttct tcttccttaa tatgagtgca agtgtcttc (2) INFORMATION FOR SEQ ID NO: 143:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 180 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..180 (D) OTHER INFORMATION: / Ceres Seq. ID 1028609
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 143: Met Ala Glu Thr Ala Glu Thr He Asn Thr Thr He Ser Ser Pro Pro 1 5 10 15
Pro Glu Ser Glu Ser Ser Thr Thr He Ser Ala Met Thr Asp Pro Thr 20 25 30
Ser Gin Glu Ala Ala Ser Lys Asp Thr Asp Leu Thr Lys Glu Ala Glu
35 40 45
Ser Glu Lys Lys Pro Gly Gly He Ser Leu Arg He Trp Pro Pro Thr 50 55 60 Gin Lys Thr Arg Asp Ala Val Leu Asn Arg Leu He Glu Thr Leu Ser 65 70 75 80
Thr Glu Ser He Leu Ser Lys Arg Tyr Gly Thr Leu Lys Ser Asp Asp
85 90 95
Ala Thr Thr Val Ala Lys Leu He Glu Glu Glu Ala Tyr Gly Val Ala 100 105 110
Ser Asn Ala Val Ser Ser Asp Asp Asp Gly He Lys He Leu Glu Leu
115 120 125
Tyr Ser Lys Glu He Ser Lys Arg Met Leu Glu Ser Val Lys Ala Arg
130 135 140 Ser Asn Ala Ser Val Gly Asn Gly Ser Val Glu Asp Ala Asn Thr Asp
145 150 155 160
Ala Ser Glu Val Ser Lys Asp Asp Ala Gly Pro Gly Ser Glu Glu Glu
165 170 175
Lys Ser Glu Ala 180
(2) INFORMATION FOR SEQ ID NO: 144: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 153 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..153
(D) OTHER INFORMATION: / Ceres Seq. ID 1028610 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 144: Met Thr Asp Pro Thr Ser Gin Glu Ala Ala Ser Lys Asp Thr Asp Leu 1 5 10 15 Thr Lys Glu Ala Glu Ser Glu Lys Lys Pro Gly Gly He Ser Leu Arg 20 25 30
He Trp Pro Pro Thr Gin Lys Thr Arg Asp Ala Val Leu Asn Arg Leu
35 40 45
He Glu Thr Leu Ser Thr Glu Ser He Leu Ser Lys Arg Tyr Gly Thr 50 55 60
Leu Lys Ser Asp Asp Ala Thr Thr Val Ala Lys Leu He Glu Glu Glu 65 70 75 80
Ala Tyr Gly Val Ala Ser Asn Ala Val Ser Ser Asp Asp Asp Gly He 85 90 95 Lys He Leu Glu Leu Tyr Ser Lys Glu He Ser Lys Arg Met Leu Glu
100 105 110
Ser Val Lys Ala Arg Ser Asn Ala Ser Val Gly Asn Gly Ser Val Glu
115 120 125
Asp Ala Asn Thr Asp Ala Ser Glu Val Ser Lys Asp Asp Ala Gly Pro 130 135 140
Gly Ser Glu Glu Glu Lys Ser Glu Ala 145 150 (2) INFORMATION FOR SEQ ID NO: 145:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 94 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..94 (D) OTHER INFORMATION: / Ceres Seq. ID 1028611
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 145: Met Gin Pro Pro Ser Arg Asn Leu Ser Lys Lys Arg Leu Met Val Leu 1 5 10 15
Leu Arg Met Leu Cys Arg Val Met Met Met Gly Leu Arg Phe Leu Ser 20 25 30
Phe He Leu Lys Arg Leu Val Arg Gly Cys Leu Asn Leu Leu Arg Leu
35 40 45
Asp Leu Met Leu Val Leu Glu Met Glu Val Trp Arg Met Leu He Leu
50 55 60
Met Leu Val Arg Phe Leu Lys Met Met Leu Val Leu Val Gin Arg Arg 65 70 75 JO
Arg Arg Val Arg Leu Glu Lys Phe Gly Phe Thr Ser Leu Leu
85 90
(2) INFORMATION FOR SEQ ID NO: 146: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 673 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..673
(D) OTHER INFORMATION: / Ceres Seq. ID 1030069 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 146: atccaaaaaa aacaaaacaa aaaattatat tcaagagaaa aaggaaaaaa tgaatttcat 60 ctccgatcag gtaaagaaac tctcaagctc aacaccagag gagccagacc acaacaagcc 120 agtcgaagga accgaaacag ctacaagacc agctaccaac gccgagctca tggcaagtgc 180 caaggttgta gctgaagctg ctcaagccgc agctcgtaac gaatcagaca aactcgacaa 240 gggtaaagtc gccggagcct ctgctgatat cttagacgct tccgagaaat acggtaagtt 300 cgatgaaaag agtagcactg gtcactacct cgacaaggct gagaagtatc tcaacgacta 360 cgagtcgtca cactccaccg gtgctggtgg tcctcctcct ccgacgagtc aggctgagcc 420 agcaagtcag cctgagccgg cggctaagaa agacgatgaa gagtctggtg gtgggcttgg 480 aggttatgcc aagatggctc aaggtttctt gaagtgattt gatctttaat tgttgttcat 540 cattttcgta ataataaatt aaataactag tatcgtttgt gactagttta tgttgcttcg 600 tttatgttta tggggagtga cgagtgagtg taataacttc tggtgatcat gaatctaatc 660 catctttgtt gtg
(2) INFORMATION FOR SEQ ID NO: 147: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 171 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..171
(D) OTHER INFORMATION: / Ceres Seq. ID 1030070 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 147: Ser Lys Lys Asn Lys Thr Lys Asn Tyr He Gin Glu Lys Lys Glu Lys 1 5 10 15 Met Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro
20 25 30
Glu Glu Pro Asp His Asn Lys Pro Val Glu Gly Thr Glu Thr Ala Thr 35 40 45 Arg Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val Ala 50 55 60
Glu Ala Ala Gin Ala Ala Ala Arg Asn Glu Ser Asp Lys Leu Asp Lys 65 70 75 80
Gly Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ser Glu Lys 85 90 95
Tyr Gly Lys Phe Asp Glu Lys Ser Ser Thr Gly His Tyr Leu Asp Lys
100 105 110
Ala Glu Lys Tyr Leu Asn Asp Tyr Glu Ser Ser His Ser Thr Gly Ala 115 120 125 Gly Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin Pro 130 135 140
Glu Pro Ala Ala Lys Lys Asp Asp Glu Glu Ser Gly Gly Gly Leu Gly 145 150 155 160
Gly Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 165 170
(2) INFORMATION FOR SEQ ID NO: 148: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1030071 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 148: Met Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro 1 5 10 15 Glu Glu Pro Asp His Asn Lys Pro Val Glu Gly Thr Glu Thr Ala Thr 20 25 30
Arg Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val Ala
35 40 45
Glu Ala Ala Gin Ala Ala Ala Arg Asn Glu Ser Asp Lys Leu Asp Lys 50 55 60
Gly Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ser Glu Lys 65 70 75 80
Tyr Gly Lys Phe Asp Glu Lys Ser Ser Thr Gly His Tyr Leu Asp Lys 85 90 95 Ala Glu Lys Tyr Leu Asn Asp Tyr Glu Ser Ser His Ser Thr Gly Ala
100 105 110
Gly Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin Pro
115 120 125
Glu Pro Ala Ala Lys Lys Asp Asp Glu Glu Ser Gly Gly Gly Leu Gly 130 135 140
Gly Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 145 150 155
(2) INFORMATION FOR SEQ ID NO: 149: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 115 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..115 (D) OTHER INFORMATION: / Ceres Seq. ID 1030072 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 149: Met Ala Ser Ala Lys Val Val Ala Glu Ala Ala Gin Ala Ala Ala Arg 1 5 10 15
Asn Glu Ser Asp Lys Leu Asp Lys Gly Lys Val Ala Gly Ala Ser Ala
20 25 30
Asp He Leu Asp Ala Ser Glu Lys Tyr Gly Lys Phe Asp Glu Lys Ser
35 40 45
Ser Thr Gly His Tyr Leu Asp Lys Ala Glu Lys Tyr Leu Asn Asp Tyr
50 55 60
Glu Ser Ser His Ser Thr Gly Ala Gly Gly Pro Pro Pro Pro Thr Ser 65 70 75 80
Gin Ala Glu Pro Ala Ser Gin Pro Glu Pro Ala Ala Lys Lys Asp Asp
85 90 95
Glu Glu Ser Gly Gly Gly Leu Gly Gly Tyr Ala Lys Met Ala Gin Gly
100 105 110
Phe Leu Lys 115
(2) INFORMATION FOR SEQ ID NO: 150:
( J SEQUENCE CHARACTERISTICS:
(A) LENGTH: 944 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA. (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..944
(D) OTHER INFORMATION: / Ceres Seq. ID 1032069 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 150: attgcgaatt ttaattgatc actctctctc tctatctctg ttcaaacatc tctcccaaag 60 taggtagaag aagatgggga cgacgttaga tgtatcaaga gcagagctag cacttgtggt 120 aatgtatttg aacaaagcag aggcaagaga taagttatgc agagctatac agtatggttc 180 caagttcttg agtggtggac aacctggtac tgctcaaaat gttgacaaat ctactagctt 240 agcaagaaaa gtcttccgtc ttttcaagtt tgtgaatgac ttgcatggtc ttatcagtcc 300 tgtgcctaaa ggaactcctc ttcctcttgt tttacttgga aagtcgaaga acgcactttt 360 atctacattc ttgttcctgg atcaaattgt ctggcttggg agatcaggaa tatataagaa 420 caaagaacga gctgagttac ttggacgtat atctctcttc tgctggatgg gatcttctgt 480 ctgcacaact ttagtcgagg ttggtgagat gggaaggctt tcttcatcaa tgaagaagat 540 cgaaaaggga ctcaagaatg gaaacaagta tcaggatgag gattatcgtg ctaagctaaa 600 aaaatcaaac gagaggtcac ttgctttgat caaatcagct atggacattg ttgtagcagc 660 tggtcttctt cagttagctc caacgaagat cactcctcgt gtcaccggag cttttggatt 720 catcacctcc atcatttctt gttaccagtt gcttccgaca cgccccaaga tcaaaacacc 780 ctgaagtcaa tcgaggaagc tggtgttaag gagaaagtca tttcagaaag tttctgttct 840 tcttattatt aaggaaattc actgctgtta taaaacatcg tataaaatac ttatttgcag 900 gaattacggt tattataaat ttatgcctca gattcttgat acgc (2) INFORMATION FOR SEQ ID NO: 151:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 236 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..236
(D) OTHER INFORMATION: / Ceres Seq. ID 1032070 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 151: Met Gly Thr Thr Leu Asp Val Ser Arg Ala Glu Leu Ala Leu Val Val 1 5 10 15
Met Tyr Leu Asn Lys Ala Glu Ala Arg Asp Lys Leu Cys Arg Ala He 20 25 30 Gin Tyr Gly Ser Lys Phe Leu Ser Gly Gly Gin Pro Gly Thr Ala Gin
35 40 45
Asn Val Asp Lys Ser Thr Ser Leu Ala Arg Lys Val Phe Arg Leu Phe 50 55 60 Lys Phe Val Asn Asp Leu His Gly Leu He Ser Pro Val Pro Lys Gly 65 70 75 80
Thr Pro Leu Pro Leu Val Leu Leu Gly Lys Ser Lys Asn Ala Leu Leu
85 90 95
Ser Thr Phe Leu Phe Leu Asp Gin He Val Trp Leu Gly Arg Ser Gly 100 105 110
He Tyr Lys Asn Lys Glu Arg Ala Glu Leu Leu Gly Arg He Ser Leu
115 120 125
Phe Cys Trp Met Gly Ser Ser Val Cys Thr Thr Leu Val Glu Val Gly
130 135 140 Glu Met Gly Arg Leu Ser Ser Ser Met Lys Lys He Glu Lys Gly Leu
145 150 155 160
Lys Asn Gly Asn Lys Tyr Gin Asp Glu Asp Tyr Arg Ala Lys Leu Lys
165 170 175
Lys Ser Asn Glu Arg Ser Leu Ala Leu He Lys Ser Ala Met Asp He 180 185 190
Val Val Ala Ala Gly Leu Leu Gin Leu Ala Pro Thr Lys He Thr Pro
195 200 205
Arg Val Thr Gly Ala Phe Gly Phe He Thr Ser He He Ser Cys Tyr 210 215 220 Gin Leu Leu Pro Thr Arg Pro Lys He Lys Thr Pro 225 230 235
(2) INFORMATION FOR SEQ ID NO: 152: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 220 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..220
(D) OTHER INFORMATION: / Ceres Seq. ID 1032071 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 152: Met Tyr Leu Asn Lys Ala Glu Ala Arg Asp Lys Leu Cys Arg Ala He 1 5 10 15
Gin Tyr Gly Ser Lys Phe Leu Ser Gly Gly Gin Pro Gly Thr Ala Gin
20 25 30
Asn Val Asp Lys Ser Thr Ser Leu Ala Arg Lys Val Phe Ar_g Leu Phe 35 40 45 Lys Phe Val Asn Asp Leu His Gly Leu He Ser Pro Val Pro Lys Gly 50 55 60
Thr Pro Leu Pro Leu Val Leu Leu Gly Lys Ser Lys Asn Ala Leu Leu 65 70 75 80
Ser Thr Phe Leu Phe Leu Asp Gin He Val Trp Leu Gly Arg Ser Gly 85 90 95
He Tyr Lys Asn Lys Glu Arg Ala Glu Leu Leu Gly Arg He Ser Leu
100 105 110
Phe Cys Trp Met Gly Ser Ser Val Cys Thr Thr Leu Val Glu Val Gly 115 120 125 Glu Met Gly Arg Leu Ser Ser Ser Met Lys Lys He Glu Lys Gly Leu 130 135 140
Lys Asn Gly Asn Lys Tyr Gin Asp Glu Asp Tyr Arg Ala Lys Leu Lys 145 150 155 160
Lys Ser Asn Glu Arg Ser Leu Ala Leu He Lys Ser Ala Met Asp He 165 170 175
Val Val Ala Ala Gly Leu Leu Gin Leu Ala Pro Thr Lys He Thr Pro 180 185 190 Arg Val Thr Gly Ala Phe Gly Phe He Thr Ser He He Ser Cys Tyr
195 200 205
Gin Leu Leu Pro Thr Arg Pro Lys He Lys Thr Pro 210 215 220 (2) INFORMATION FOR SEQ ID NO: 153: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 769 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..769 (D) OTHER INFORMATION: / Ceres Seq. ID 1033557
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 153: ggtatcgtcc gtagacgata gaggttccac actatgtaaa ggagaccgga gaaacaaagg 60 aactgggttt ggagataaga agtgggaact tgaatggctt ccttatccac ttccgttgta 120 gcttcggctt cgtcgcgttt atggaatcct gctgcctcca acggcaagat ttgcgttcct 180 tctgcttcgc tttctctgcg tacgggttgt agacggagtt cgtcctctct cacttcttcc 240 gcttcttcgc aattgcttca ttgctcgttt ctctcgtcgc ctgtttccct agcgtctcca 300 ttttctggtt tgtccattgc gtttgatctc agcagtcaaa ctagtggact gaatggccag 360 agacgcagag gccttgtggt tagagctgga aaagctgctc tgtgtcaaac taagagaagc 420 agatcaagaa aatctctagc taggactcat ggtttccgta gaaggatgag gaccactagc 480 ggtagagcaa ccataaagcg tcgacgtgcc aagggacgtt ggaacctctg tcccaagtcc 540 aaccctagca gcggcaaacg ggcttgaagt ttgtttctct cttcactcta tctgtaatct 600 tgtttcatgt gctttttttc caccagaaga tacaatgaga aacatggttc gttgagctct 660 tttctgcgtt ttaactctct tgcatccttg attcgtttat aaatcaatgt tcttggaatt 720 catcacatgt actactatac tacttgcttc attgaatttg ttactactc (2) INFORMATION FOR SEQ ID NO: 154: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 157 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..157 (D) OTHER INFORMATION: / Ceres Seq. ID 1033558
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 154: Met Ala Ser Leu Ser Thr Ser Val Val Ala Ser Ala Ser Ser Arg Leu 1 5 10 15
Trp Asn Pro Ala Ala Ser Asn Gly Lys He Cys Val Pro Ser Ala Ser 20 25 30
Leu Ser Leu Arg Thr Gly Cys Arg Arg Ser Ser Ser Ser Leu Thr Ser
35 40 45
Ser Ala Ser Ser Gin Leu Leu His Cys Ser Phe Leu Ser Ser Pro Val 50 55 60 Ser Leu Ala Ser Pro Phe Ser Gly Leu Ser He Ala Phe Asp Leu Ser 65 70 75 80
Ser Gin Thr Ser Gly Leu Asn Gly Gin Arg Arg Arg Gly Leu Val Val
85 90 95
Arg Ala Gly Lys Ala Ala Leu Cys Gin Thr Lys Arg Ser Arg Ser Arg 100 105 110
Lys Ser Leu Ala Arg Thr His Gly Phe Arg Arg Arg Met Arg Thr Thr
115 120 125
Ser Gly Arg Ala Thr He Lys Arg Arg Arg Ala Lys Gly Arg Trp Asn 130 135 140 Leu Cys Pro Lys Ser Asn Pro Ser Ser Gly Lys Arg Ala 145 150 155
(2) INFORMATION FOR SEQ ID NO: 155: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 679 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..679 (D) OTHER INFORMATION: / Ceres Seq. ID 1034688
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 155: aaaaaaaaac aaaacaaaaa attatattca agagaaaaag gaaaaaatga atttcatctc 60 cgatcaggta aagaaactct caagctcaac accagaggag ccagaccaca acaagccagt 120 cgaaggaacc gaaacagcta caagaccagc taccaacgcc gagctcatgg caagtgccaa 180 ggttgtagct gaagctgctc aagccgcagc tcgtaacgaa tcagacaaac tcgacaaggg 240 taaagtcgcc ggagcctctg ctgatatctt agacgctgcc gagaaatacg gtaagttcga 300 tgaaaagagt agcactggtc agtacctcga caaggctgag aagtatctca acgactacga 360 gtcgtcacac tccaccggtg ctggtggtcc tcctcctcca acgagtcagg ctgagccagc 420 aagtcagcct gagccggcgg ctaagaaaga cgatgaagag tctggtggtg ggcttggagg 480 ttatgccaag atggctcaag gtttcttgaa gtgatttgat ctttaattgt tgttcatcat 540 tttcgtaata ataaattaaa taactagtat cgtttgtgac tagtttatgt tgcttcgttt 600 atgtttatgg ggagtgacga gtgagtgtaa taacttctgg tgatcatgaa tctaatccat 660 ctttgttgtg attatgctc (2) INFORMATION FOR SEQ ID NO: 156: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 170 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..170
(D) OTHER INFORMATION: / Ceres Seq. ID 1034689 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 156:
Lys Lys Asn Lys Thr Lys Asn Tyr He Gin Glu Lys Lys Glu Lys Met 1 5 10 15
Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro Glu 20 25 30 Glu Pro Asp His Asn Lys Pro Val Glu Gly Thr Glu Thr Ala Thr Arg 35 40 45
Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val Ala Glu
50 55 60
Ala Ala Gin Ala Ala Ala Arg Asn Glu Ser Asp Lys Leu Asp Lys Gly 65 70 75 80
Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ala Glu Lys Tyr
85 90 95
Gly Lys Phe A.sp Glu Lys Ser Ser Thr Gly Gin Tyr Leu Asp Lys Ala 100 105 110 Glu Lys Tyr Leu Asn Asp Tyr Glu Ser Ser His Ser Thr Gly Ala Gly 115 120 125
Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin Pro Glu
130 135 140
Pro Ala Ala Lys Lys Asp Asp Glu Glu Ser Gly Gly Gly Leu Gly Gly 145 150 155 160
Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 165 170
(2) INFORMATION FOR SEQ ID NO: 157: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 155 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1034690 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 157: Met Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro 1 5 10 15 Glu Glu Pro Asp His Asn Lys Pro Val Glu Gly Thr Glu Thr Ala Thr 20 25 30
Arg Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val Ala
35 40 45
Glu Ala Ala Gin Ala Ala Ala Arg Asn Glu Ser Asp Lys Leu Asp Lys 50 55 60
Gly Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ala Glu Lys 65 70 75 80
Tyr Gly Lys Phe Asp Glu Lys Ser Ser Thr Gly Gin Tyr Leu Asp Lys 85 90 95 Ala Glu Lys Tyr Leu Asn Asp Tyr Glu Ser Ser His Ser Thr Gly Ala
100 105 110
Gly Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin Pro
115 120 125
Glu Pro Ala Ala Lys Lys Asp Asp Glu Glu Ser Gly Gly Gly Leu Gly 130 135 140
Gly Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 145 150 155
(2) INFORMATION FOR SEQ ID NO: 158: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 115 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: / Ceres Seq. ID 1034691 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 158: Met Ala Ser Ala Lys Val Val Ala Glu Ala Ala Gin Ala Ala Ala Arg 1 5 10 15
Asn Glu Ser Asp Lys Leu Asp Lys Gly Lys Val Ala Gly Ala Ser Ala
20 25 30
Asp He Leu Asp Ala Ala Glu Lys Tyr Gly Lys Phe Asp Glu Lys Ser 35 40 45
Ser Thr Gly Gin Tyr Leu Asp Lys Ala Glu Lys Tyr Leu Asn Asp Tyr
50 55 60
Glu Ser Ser His Ser Thr Gly Ala Gly Gly Pro Pro Pro Pro Thr Ser 65 70 75 80 Gin Ala Glu Pro Ala Ser Gin Pro Glu Pro Ala Ala Lys Lys Asp Asp
85 90 95
Glu Glu Ser Gly Gly Gly Leu Gly Gly Tyr Ala Lys Met Ala Gin Gly
100 105 110
Phe Leu Lys 115
(2) INFORMATION FOR SEQ ID NO: 159: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 471 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) ( ix ) FEATURE :
(A) NAME/KEY : -
( B) LOCATION : 1 . . 471
(D) OTHER INFORMATION: / Ceres Seq. ID 1035033 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 159: atataaaaaa aaaacttatt ttgttcattc ttttaagttt aaaaacagtc aattcattta 60 tatcatctat gatgaagaaa ctcattcaag tctcgttcac tgttatgatt atcttcacca 120 ttcttgtgct aggagtggtg gcaaatgagg ggctaggaaa accaaaaaaa caatgtaatg 180 agattctaaa gcaatccaac tgtgttgctg cagagtgtga ctctatgtgt gtgaagaaga 240 gggggaaagg agccggttac tgctctcctt ctaaaaagtg ttactgctat tatcattgcc 300 cttaacgatt ttattattta caataataag agatttatga taaagtagta aaataatgaa 360 tcgggtgttt atagcctaac gattgatata gttgtctcta tcaaataaac tatatagact 420 aaaagtaata ataataatga caatcataac tcagaagttt ttgtttagtc c (2) INFORMATION FOR SEQ ID NO: 160:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 100 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..100
(D) OTHER INFORMATION: / Ceres Seq. ID 1035034
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 160:
He Lys Lys Lys Leu He Leu Phe He Leu Leu Ser Leu Lys Thr Val
1 5 10 15
Asn Ser Phe He Ser Ser Met Met Lys Lys Leu He Gin Val Ser Phe
20 25 30
Thr Val Met He He Phe Thr He Leu Val Leu Gly Val Val Ala Asn
35 40 45
Glu Gly Leu Gly Lys Pro Lys Lys Gin Cys Asn Glu He Leu Lys Gin
50 55 60
Ser Asn Cys Val Ala Ala Glu Cys Asp Ser Met Cys Val Lys Lys Arg 65 70 75 80
Gly Lys Gly Ala Gly Tyr Cys Ser Pro Ser Lys Lys Cys Tyr Cys Tyr
85 90 95
Tyr His Cys Pro 100
.2) INFORMATION FOR SEQ ID NO: 161: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 78 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..78
(D) OTHER INFORMATION: / Ceres Seq. ID 1035035
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 161:
Met Met Lys Lys Leu He Gin Val Ser Phe Thr Val Met He He Phe
1 5 10 15
Thr He Leu Val Leu Gly Val Val Ala Asn Glu Gly Leu Gly Lys Pro
20 25 30
Lys Lys Gin Cys Asn Glu He Leu Lys Gin Ser Asn Cys Val Ala Ala
35 40 45
Glu Cys Asp Ser Met Cys Val Lys Lys Arg Gly Lys Gly Ala Gly Tyr
50 55 60
Cys Ser Pro Ser Lys Lys Cys Tyr Cys Tyr Tyr His Cys Pro 65 70 75
(2) INFORMATION FOR SEQ ID NO: 162: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 77 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..77
(D) OTHER INFORMATION: / Ceres Seq. ID 1035036 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 162: Met Lys Lys Leu He Gin Val Ser Phe Thr Val Met He He Phe Thr 1 5 10 15
He Leu Val Leu Gly Val Val Ala Asn Glu Gly Leu Gly Lys Pro Lys
20 25 30
Lys Gin Cys Asn Glu He Leu Lys Gin Ser Asn Cys Val Ala Ala Glu
35 40 45
Cys Asp Ser Met Cys Val Lys Lys Arg Gly Lys Gly Ala Gly Tyr Cys
50 55 60
Ser Pro Ser Lys Lys Cys Tyr Cys Tyr Tyr His Cys Pro
65 70 75 (2) INFORMATION FOR SEQ ID NO: 163:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 985 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..985 (D) OTHER INFORMATION: / Ceres Seq ID 1035071
(xi) SEQUENCE DESCRIPTION: SEQ TD NO: 163 taacgcactc tcttctccga atctagggtt tttgtctcta gcctcctcaa gctttgcaaa 60 caatcatggc gacccagatc agcaagaaga gaaagttcgt agccgatggt gtgttttacg 120 ctgaactcaa tgaggttcta accagagagc ttgctgagga tggttactct ggtgttgagg 180 ttcgcgtcac tcctatgcgt actgagatca tcattagagc cactcgtact caaaacgttc 240 tcggtgagaa gggaaggagg attagggaat tgacatctct tgtacaaaag agattcaaat 300 ttcctcagga cagtgttgag ctttatgctg agaaggttgc taacagaggt ctttgtgcta 360 ttgctcaggc tgagtctctt cgttacaagc ttcttggtgg tcttgctgtt cgtagggcgt 420 gctatggtgt tttaaggttt gttatggaga gtggagctaa aggatgcgaa gtcattgtga 180 gtggaaaact ccgtgctgca cgtgctaagt agatgaagtt caaggatggt tacatggttt 540 cctcaggtca gccaaccaag gaatacattg atgctgcagt taggcatgtt cttcttagac 600 agggtgtgct tggtctcaag gtgaagatca tgcttgactg ggaccccaag ggcaaacaag 660 gaccgatgac accattgcct gatgttgtga tcatccatac accgaaagaa gatgatgtat 720 acattgcacc tgctcaggtt gttactcaag ctgcttttgt accggaagct ccattaacca 780 ccacagatta tccagcaatg ccagttgctt agagagcctt ttcgttttct ggtttaaaac 840 ccaatgggga tggttctttt tttgggacag tactagtttt ctcatgttat tctaagttaa 900 tacttaaagt tctggaggtt gaattacatc aaggatatga atgtatgttt ttcgttatct 960 tttgtttaaa ttttatttat ctatt (2) INFORMATION FOR SEQ ID NO: 164: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 148 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..148
(D) OTHER INFORMATION: / Ceres Seq. ID 1035072
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 164: Met Ala Thr Gin He Ser Lys Lys Arg Lys Phe Val Ala Asp Gly Val 1 5 10 15
Phe Tyr Ala Glu Leu Asn Glu Val Leu Thr Arg Glu Leu Ala Glu Asp 20 25 30 Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He 35 40 45
He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg
50 55 60
Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys Arg Phe Lys Phe Pro 65 70 75 80
Gin Asp Ser Val Glu Leu Tyr Ala Glu Lys Val Ala Asn Arg Gly Leu
85 90 95
Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly 100 105 110 Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu 115 120 125
Ser Gly Ala Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala
130 135 140
Ala Arg Ala Lys 145
(2) INFORMATION FOR SEQ ID NO: 165: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 105 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..105
(D) OTHER INFORMATION: / Ceres Seq. ID 1035073 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 165: Met Arg Thr Glu He He He Arg Ala Thr Arg Thr Gin Asn Val Leu 1 5 10 15 Gly Glu Lys Gly Arg Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys
20 25 30
Arg Phe Lys Phe Pro Gin Asp Ser Val Glu Leu Tyr Ala Glu Lys Val
35 40 45
Ala Asn Arg Gly Leu Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr 50 55 60
Lys Leu Leu Gly Gly Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu 65 70 " 75 80
Arg Phe Val Met Glu Ser Gly Ala Lys Gly Cys Glu Val He Val Ser 85 90 95 Gly Lys Leu Arg Ala Ala Arg Ala Lys
100 105
(2) INFORMATION FOR SEQ ID NO: 166: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 99 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..99
(D) OTHER INFORMATION: / Ceres Seq. ID 1035074 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 166: Met Lys Phe Lys Asp Gly Tyr Met Val Ser Ser Gly Gin Pro Thr Lys 1 5 10 15
Glu Tyr He Asp Ala Ala Val Arg His Val Leu Leu Arg Gin Gly Val 20 25 30 Leu Gly Leu Lys Val Lys He Met Leu Asp Trp Asp Pro Lys Gly Lys
35 40 45
Gin Gly Pro Met Thr Pro Leu Pro Asp Val Val He He His Thr Pro
50 55 60
Lys Glu Asp Asp Val Tyr He Ala Pro Ala Gin Val Val Thr Gin Ala 65 70 75 80
Ala Phe Val Pro Glu Ala Pro Leu Thr Thr Thr Asp Tyr Pro Ala Met
85 90 95
Pro Val Ala
(2) INFORMATION FOR SEQ ID NO: 167: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 759 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..759
(D) OTHER INFORMATION: / Ceres Seq. ID 13765E
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 167: atccgcagaa aaccctattg ctcccctttg ctcaagctca gtgcctcttt gcagcgaaag 60 ctcaaccaac aagacgatga ttatctcaga gaacaatcgc agagagatct gcaaatacct 120 tttcaaagag ggagtatgct ttgctaagaa ggatttcaat ctcccaaagc atccgttgat 180 tgatgtacca aacctgcaag tgattaagct catgcagagt ttcaagtcca aggagtacgt 240 tagggagaca tttgcgtgga tgcattatta ttggtttctg actaatgaag gaattgagtt 300 cttgagaact tatcttaacc ttccttccga tgttgtccct gctactttga agaagtctgc 360 taagcccggt ggtcgtccct ttggtggccc acctggtgat cgccaaagag gaccacctcg 420 ctctgatgga gaccgtccca gatttggtga ccgtgatgga taccgtggag gcccacgagg 480 tggtgatgag aagagtggag ctccagctga tttccagccg tctttccaag gaggtggtgg 540 taggcctggt tttggccgtg gtgcaggcgg ttacagtgca gcagcaccat ctggttcagg 600 gttcccttga aaaatttσtt gtcatattgc gacgatggaa ggacagtttt gttttttgtt 660 ctagttctgt ttgtgta_tg caaatctgga atctataatc tatctattac cttcaccttg 720 gtttaaacga acaaatcctg tagtttcagg attagtgcc (2) INFORMATION FOR SEQ ID NO: 168
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 202 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..202
(D) OTHER INFORMATION: / Ceres Seq. ID 1376588
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 168:
Ser Ala Glu Asn Pro He Ala Pro Leu Cys Ser Ser Ser Val Pro Leu
1 5 10 15
Cys Ser Glu Ser Ser Thr Asn Lys Thr Met He He Ser Glu Asn Asn
20 25 30
Arg Arg Glu He Cys Lys Tyr Leu Phe Lys Glu Gly Val Cys Phe Ala
35 40 45
Lys Lys Asp Phe Asn Leu Pro Lys His Pro Leu He Asp Val Pro Asn
50 55 60
Leu Gin Val He Lys Leu Met Gin Ser Phe Lys Ser Lys Glu Tyr Val
65 70 75 80
Arg Glu Thr Phe Ala Trp Met His Tyr Tyr Trp Phe Leu Thr Asn Glu
85 90 95
Gly He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro Ser Asp Val Val
100 105 110
Pro Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly 115 120 125
Gly Pro Pro Gly Asp Arg Gin Arg Gly Pro Pro Arg Ser Asp Gly Asp
130 135 140
Arg Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg Gly Gly Pro Arg Gly 145 150 155 160
Gly Asp Glu Lys Ser Gly Ala Pro Ala Asp Phe Gin Pro Ser Phe Gin
165 170 175
Gly Gly Gly Gly Arg Pro Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser 180 185 190 Ala Ala Ala Pro Ser Gly Ser Gly Phe Pro 195 200
(2) INFORMATION FOR SEQ ID NO: 169: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 177 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..177
(D) OTHER INFORMATION: / Ceres Seq. ID 1376589 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 169: Met He He Ser Glu Asn Asn Arg Arg Glu He Cys Lys Tyr Leu Phe 1 5 10 15
Lys Glu Gly Val Cys Phe Ala Lys Lys Asp Phe Asn Leu Pro Lys His
20 25 30
Pro Leu He Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser 35 40 45 Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His Tyr 50 55 60
Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu 65 70 75 80
Asn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys Se__ Ala Lys 85 90 95
Pro Gly Gly Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg Gin Arg Gly
100 105 110
Pro Pro Arg Ser Asp Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly 115 120 125 Tyr Arg Gly Gly Pro Arg Gly Gly Asp Glu Lys Ser Gly Ala Pro Ala 130 135 140
Asp Phe Gin Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro Gly Phe Gly 145 150 155 160
Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser Gly Phe 165 170 175
Pro
(2) INFORMATION FOR SEQ ID NO: 170: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 132 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..132
(D) OTHER INFORMATION: / Ceres Seq. ID 1376590 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 170: Met Gin Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp 1 5 10 15
Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg 20 25 30
Thr Tyr Leu Asn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys
35 40 45
Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg
50 55 60
Gin Arg Gly Pro Pro Arg Ser Asp Gly Asp Arg Pro Arg Phe Gly Asp 65 70 75 80
Arg Asp Gly Tyr Arg Gly Gly Pro Arg Gly Gly Asp Glu Lys Ser Gly
85 90 95
Ala Pro Ala Asp Phe Gin Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro
100 105 110
Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly
115 120 125
Ser Gly Phe Pro
130 (2) INFORMATION FOR SEQ ID NO: 171: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 645 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..645 (D) OTHER INFORMATION: / Ceres Seq. ID 1378581 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 171: gatttcccat tttggttgca gcgatcggag agctctgacg gcaccagcca cctctgcggc 60 ttcgcaaatc caaataagct gtggatgaaa cgaagaatcc tagatttctg aatggcgaca 120 ccatttatag cgggggttgc agtagctgca acagcacttg ctggtagata tggaatccaa 180 gcatggcaag cattcaaggc aaggccacca aggcccaaaa ttaagaaatt ttatgagggc 240 ggtttccagc ctacgatgac gaaaagggaa gctgctctca ttcttggcgt cagggagagt 300 gtagcggcgg aaaaggtgaa ggaagcacac aggaaggtaa tg(_ agcaaa ccatccagat 360 gcaggtggta gccatttcct agcctctaag atcaatgaag ctaaagacgt gatgctaggc 420 aaaactaaaa acagcggatc cgctttttga tgcaaatttc aatcaaaaga cttccttatg 480 aatcatctta tgttatagga ctgtaatgtc aaaatgcaga ttttatgtta atttataagc 540 ttgtggtctg tttgtgacac ataaagactc gaatcttttc tttcacttgt tgtcgctgaa 600 aagaacacaa aaataaaaac gcaaagcaga agggcgttct agtcg (2) INFORMATION FOR SEQ ID NO: 172: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 112 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..112
(D) OTHER INFORMATION: / Ceres Seq. ID 1378582 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 172: Met Ala Thr Pro Phe He Ala Gly Val Ala Val Ala Ala Thr Ala Leu 1 5 10 15
Ala Gly Arg Tyr Gly He Gin Ala Trp Gin Ala Phe Lys Ala Arg Pro
20 25 30
Pro Arg Pro Lys He Lys Lys Phe Tyr Glu Gly Gly Phe Gin Pro Thr
35 40 45
Met Thr Lys Arg Glu Ala Ala Leu He Leu Gly Val Arg Glu Ser Val
50 55 60
Ala Ala Glu Lys Val Lys Glu Ala His Arg Lys Val Met Val Ala Asn 65 70 75 80
His Pro Asp Ala Gly Gly Ser His Phe Leu Ala Ser Lys He Asn Glu 85 90 95 Ala Lys Asp Val Met Leu Gly Lys Thr Lys Asn Ser Gly Ser Ala Phe
100 105 110
(2) INFORMATION FOR SEQ ID NO: 173: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 64 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..64
(D) OTHER INFORMATION: / Ceres Seq. I D 1378583
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 173:
Met Thr Lys Arg Glu Ala Ala Leu He Leu Gly Val Arg Glu Ser Val
1 5 10 15
Ala Ala Glu Lys Val Lys Glu Ala His Arg Lys Val Met Val Ala Asn
20 25 30
His Pro Asp Ala Gly Gly Ser His Phe Leu Ala Ser Lys He Asn Glu
35 40 45
Ala Lys Asp Val Met Leu Gly Lys Thr Lys Asn Ser Gly Ser Ala Phe 50 55 60
(2) INFORMATION FOR SEQ ID NO: 174: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 803 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..803
(D) OTHER INFORMATION: / Ceres Seq. ID 1383462 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 174: aggacacgtt tctatctaga gagaacacaa cacatcgaac catggagaaa tcaacaagaa 60 ccctattcat aaccatcgtg ataacctcca tgttgctagg gtttggaaac tctgatcttg 120 ctcaggacag agaggagtgt acgaaccagc tcatagaact atccacgtgt attccgtacg 180 ttggaggaga cgccaaggct ccaacaaaag attgttgtgc agggtttggc caagttataa 240 gaaagagtga gaagtgtgtt tgcatattgg tcagagacaa agatgatcct caacttggta 300 tcaagattaa cgcaacccta gccgctcatc ttccctccgc ttgtcatatc acggctccta 360 acatcactga ctgtatttcg attctgcatc tacctcgtaa ctcaacattg gctaaagagt 420 ttgagaactt aggaaggatt gaagacaact acaactccac atctcctaca caaattcata 480 aagatgggac aggaggagga aaagccgaac cagtgaagag taatggatgg aaggagaaga 540 gttggttggg tgttgagctt ttaatatatt tgctagtttc tctcatcttc ttttaattac 600 ttcctttctt taatgttcct ttgctttatt attacaataa cttataagat atctatttat 660 atatgagaca catgcatgtg tttgcgatct atatgcatgt aaatgagtca ctggttaatt 720 tttaatcacg aagcgtacat tttaatttcg ttgttgccaa ttgatcttgt acgttagtga 780 attttatgga ttatcgactt act
(2) INFORMATION FOR SEQ ID NO: 175: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 197 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..197
(D) OTHER INFORMATION: / Ceres Seq. ID 1383463
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 175:
Asp Thr Phe Leu Ser Arg Glu Asn Thr Thr His Arg Thr Met Glu Lys
10 15 Ser Thr Arg Thr Leu Phe He Thr He Val He Thr Ser Met Leu Leu
20 25 30
Gly Phe Gly Asn Ser Asp Leu Ala Gin Asp Arg Glu Glu Cys Thr Asn 35 40 45 Gin Leu He Glu Leu Ser Thr Cys He Pro Tyr Val Gly Gly Asp Ala 50 55 60
Lys Ala Pro Thr Lys Asp Cys Cys Ala Gly Phe Gly Gin Val He Arg 65 70 75 80
Lys Ser Glu Lys Cys Val Cys He Leu Val Arg Asp Lys Asp Asp Pro 85 90 95
Gin Leu Gly He Lys He Asn Ala Thr Leu Ala Ala His Leu Pro Ser
100 105 110
Ala Cys His He Thr Ala Pro Asn He Thr Asp Cys He Ser He Leu 115 120 125 His Leu Pro Arg Asn Ser Thr Leu Ala Lys Glu Phe Glu Asn Leu Gly 130 135 140
Arg He Glu Asp Asn Tyr Asn Ser Thr Ser Pro Thr Gin He His Lys 145 150 155 160
Asp Gly Thr Gly Gly Gly Lys Ala Glu Pro Val Lys Ser Asn Gly Trp 165 170 175
Lys Glu Lys Ser Trp Leu Gly Val Glu Leu Leu He Tyr Leu Leu Val
180 185 190
Ser Leu He Phe Phe 195 (2) INFORMATION FOR SEQ ID NO: 176: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 184 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptics
(B) LOCATION: 1..184 (D) OTHER INFORMATION: / Ceres Seq. ID 1383464
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 176: Met Glu Lys Ser Thr Arg Thr Leu Phe He Thr He Val He Thr Ser 1 5 10 15
Met Leu Leu Gly Phe Gly Asn Ser Asp Leu Ala Gin Asp Arg Glu Glu 20 25 30
Cys Thr Asn Gin Leu He Glu Leu Ser Thr Cys He Pro Tyr Val Gly
35 40 45
Gly Asp Ala Lys Ala Pro Thr Lys Asp Cys Cys Ala Gly Phe Gly Gin 50 55 60 Val He Arg Lys Ser Glu Lys Cys Val Cys He Leu Val Arg Asp Lys 65 70 75 80
Asp Asp Pro Gin Leu Gly He Lys He Asn Ala Thr Leu Ala Ala His
85 90 95
Leu Pro Ser Ala Cys His He Thr Ala Pro Asn He Thr Asp Cys He 100 105 110
Ser He Leu His Leu Pro Arg Asn Ser Thr Leu Ala Lys Glu Phe Glu
115 120 125
Asn Leu Gly Arg He Glu Asp Asn Tyr Asn Ser Thr Ser Pro Thr Gin
130 135 140 He His Lys Asp Gly Thr Gly Gly Gly Lys Ala Glu Pro Val Lys Ser
145 150 155 160
Asn Gly Trp Lys Glu Lys Ser Trp Leu Gly Val Glu Leu Leu He Tyr
165 170 175
Leu Leu Val Ser Leu He Phe Phe 180
(2) INFORMATION FOR SEQ ID NO: 177: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 168 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..168
(D) OTHER INFORMATION: / Ceres Seq. ID 1383465 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 177:
Met Leu Leu Gly Phe Gly Asn Ser Asp Leu Ala Gin Asp Arg Glu Glu 1 5 10 15
Cys Thr Asn Gin Leu He Glu Leu Ser Thr Cys He Pro Tyr Val Gly 20 25 30 Gly Asp Ala Lys Ala Pro Thr Lys Asp Cys Cys Ala Gly Phe Gly Gin 35 40 45
Val He Arg Lys Ser Glu Lys Cys Val Cys He Leu Val Arg Asp .Lys
50 55 60
Asp Asp Pro Gin Leu Gly He Lys He Asn Ala Thr Leu Ala Ala His 65 70 75 80
Leu Pro Ser Ala Cys His He Thr Ala Pro Asn He Thr Asp Cys He
85 90 95
Ser He Leu His Leu Pro Arg Asn Ser Thr Leu Ala Lys Glu Phe Glu 100 105 110 Asn Leu Gly Arg He Glu Asp Asn Tyr Asn Ser Thr Ser Pro Thr Gin 115 120 125
He His Lys Asp Gly Thr Gly Gly Gly Lys Ala Glu Pro Val Lys Ser
130 135 140
Asn Gly Trp Lys Glu Lys Ser Trp Leu Gly Val Glu Leu Leu He Tyr 145 150 155 160
Leu Leu Val Ser Leu He Phe Phe
165 (2) INFORMATION FOR SEQ ID NO: 178: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 968 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..968
(D) OTHER INFORMATION: / Ceres Seq. ID 1386215 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 178: aagaggaaaa caaaactgca aaaacaaaaa taaaaaaaac atcgcacaag aaaataaaag 60 atttgtagaa tcaactaaga aaatggctag cactatgatg actacattgc ctcagttcaa 120 tggtcttcga gccaccaaaa tctctgcagc tcctgtacaa ggcctggcaa gtgttcagcc 180 catgagacgc aagggaaatg gagctttggg tgcaaagtgt gacttcatcg gttcatcaac 240 aaatctgata atggtaacgt cgacgaccct gatgttgttc gcggggagat tcggacttgc 300 gccatcagcc aataggaagg cgacagctgg acttaggttg gaggcacgtg actcaggtct 360 acaaacgggt gacccggccg ggttcacgct tgcggacact ttggcttgtg cctccaatct 420 aaccccaatt tcaccttctt ccccaaatct cgagtcaatg aagacgtccc cgatgaaacg 480 cctctcactc cgaaatcggc aatggctctt gtcgcagctg gaaatatctc ggtggctaat 540 atgaataaag cggtggctct gttaaaggaa gaagctctta agaagatcat agcagctaaa 600 acggccaagt tgagagctaa aggtgcattg acgaatcttc aggatattgt tattcgacag 660 agtaaggtca ccggcaagag gaaggaagat gaacgctgat tttctaaatc ttgatagcaa 720 ttttactggt acgtagagct tttgtgtgat atatcgcttc tagggttcaa ggaaagacta 780 cttttttgcg gttattggcc atttatcttg gtgaatttta gttcatattc agacgtgttt 840 gatcaaatgt ctcccagaga aagctggaga ctttgaatta ggatacatta gggcttttat 900 tttgtacaat ggtgtgtgta agactcagtg acattcattc atattaatcg gttccatctt 960 caatcttt (2) INFORMATION FOR SEQ ID NO: 179: ( i ) SEQUENCE CHARACTERISTICS :
(A) LENGTH : 180 amino acids
( B ) TYPE : amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..180 (D) OTHER INFORMATION: / Ceres Seq. ID 1386216
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 179: Arg Gly Lys Gin Asn Cys Lys Asn Lys Asn Lys Lys Asn He Ala Gin 1 5 10 15
Glu Asn Lys Arg Phe Val Glu Ser Thr Lys Lys Met Ala Ser Thr Met 20 25 30
Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg Ala Thr Lys He Ser
35 40 45
Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin Pro Met Arg Arg Lys 50 55 60 Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe He Gly Ser Ser Thr 65 70 75 80
Asn Leu He Met Val Thr Ser Thr Thr Leu Met Leu Phe Ala Gly Arg
85 90 95
Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala Thr Ala Gly Leu Arg 100 105 110
Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly Asp Pro Ala Gly Phe
115 120 125
Thr Leu Ala Asp Thr Leu Ala Cys Ala Ser Asn Leu Thr Pro He Ser
130 135 140 Pro Ser Ser Pro Asn Leu Glu Ser Met Lys Thr Ser Pro Met Lys Arg
145 150 155 160
Leu Ser Leu Arg Asn Arg Gin Trp Leu Leu Ser Gin Leu Glu He Ser
165 170 175
Arg Trp Leu He 180
(2) INFORMATION FOR SEQ ID NO: 180: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 153 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..153
(D) OTHER INFORMATION: / Ceres Seq. ID 1386217 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 180: Met Ala Ser Thr Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg 1 5 10 15 Ala Thr Lys He Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin 20 25 30
Pro Met Arg Arg Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe
35 40 45
He Gly Ser Ser Thr Asn Leu He Met Val Thr Ser Thr Thr Leu Met 50 55 60
Leu Phe Ala Gly Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala 65 70 75 80
Thr Ala Gly Leu Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly 85 90 95 Asp Pro Ala Gly Phe Thr Leu Ala Asp Thr Leu Ala Cys Ala Ser Asn 100 105 110
Leu Thr Pro He Ser Pro Ser Ser Pro Asn Leu Glu Ser Met Lys Thr 115 120 125
Ser Pro Met Lys Arg Leu Ser Leu Arg Asn Arg Gin Trp Leu Leu Ser
130 135 140
Gin Leu Glu He Ser Arg Trp Leu He 145 150
(2) INFORMATION FOR SEQ ID NO: 181: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 149 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..149
(D) OTHER INFORMATION: / Ceres Seq. ID 1386218 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 181: Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg Ala Thr Lys He 1 5 10 15 Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin Pro Met Arg Arg
20 25 30
Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe He Gly Ser Ser
35 40 ' 45
Thr Asn Leu He Met Val Thr Ser Thr Thr Leu Met Leu Phe Ala Gly 50 55 60
Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala Thr Ala Gly Leu 65 70 75 80
Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly Asp Pro Ala Gly 85 90 95 Phe Thr Leu Ala Asp Thr Leu Ala Cys Ala Ser Asn Leu Thr Pro He
100 105 110
Ser Pro Ser Ser Pro Asn Leu Glu Ser Met Lys Thr Ser Pro Met Lys
115 120 125
Arg Leu Ser Leu Arg Asn Arg Gin Trp Leu Leu Ser Gin Leu Glu He 130 135 140
Ser Arg Trp Leu He 145
(2) INFORMATION FOR SEQ ID NO: 182: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 65 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 2025156 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 182: Met Ala Leu Val Ala Ala Gly Asn He Ser Val Ala Asn Met Asn Lys 1 5 10 15
Ala Val Ala Leu Leu Lys Glu Glu Ala Leu Lys Lys He He Ala Ala
20 25 30
Lys Thr Ala Lys Leu Arg Ala Lys Gly Ala Leu Thr Asn Leu Gin Asp 35 40 45
He Val He Arg Gin Ser Lys Val Thr Gly Lys Arg Lys Glu Asp Glu
50 55 60
Arg 65 (2) INFORMATION FOR SEQ ID NO: 183: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 770 base pairs ( B ) TYPE: nucleic acid
( C ) STRANDEDNESS: single
( D ) TOPOLOGY: linear
( ii ) MOLECULE TYPE : DNA (genomic) ( ix ) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..770
(D) OTHER INFORMATION: / Ceres Seq . ID 1388499 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 183 aaaaaactca ttctcataac aattccctta actctatctc taggtgactt aagagtaaaa 60 aatggtagag gcagaggttg aagtagatgt ggaaatcaaa tctacggctg ataagttttt 120 catgttctct agaagatcac aacatgcctc caaagccact cgctatgtac agggatgtga 180 tctgctcgaa ggcgagtggg gcgaagttgg aagcatactc ttgtggaaat taactgttga 240 tggagagcca aaagtgtcaa aggatatgat tgaggcgatt gatatgaaga tgaatatgat 300 ccagtggagg gtgttagagg gacctctgaa ggaagagtac aatattttct cgaaaacgat 360 gaaagtaagc cctaagcaag gagggtctgg aagtgtggtg aagtggaact tgaagtatga 420 gagaattgat gaaaaggtgg ctcacctaga gaggctcctt cagttcttcg tcgaatgtgt 480 taacgagatt gaccaatacc tattgtctga gggttagggg acttttctcc ctggcttatg 540 tgtgggagag ttattgtatg cgtacgtgta aggactcttc ttgtgtttta tatgtctttc 600 tcaataatgt gatatcttga gatttagaag agaggtatcc aagtgtgcta tacctcatgt 660 cttcaagttg gaagttgtat aacattttaa gttgcttatg agtttctcat atatgtagtg 720 tgtttgttgg ttgaaaaatc atattataat gcaacgatac catgtttttt (2) INFORMATION FOR SEQ ID NO: 184:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..151 (D) OTHER INFORMATION: / Ceres Seq. ID 1388500 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 184: Met Val Glu Ala Glu Val Glu Val Asp Val Glu He Lys Ser Thr Ala 1 5 10 15
Asp Lys Phe Phe Met Phe Ser Arg Arg Ser Gin His Ala Ser Lys Ala
20 25 30
Thr Arg Tyr Val Gin Gly Cys Asp Leu Leu Glu Gly Glu Trp Gly Glu
35 40 45
Val Gly Ser He Leu Leu Trp Lys Leu Thr Val Asp Gly Glu Pro Lys
50 55 60
Val Ser Lys Asp Met He Glu Ala He Asp Met Lys Met Asn Met He 65 70 75 80
Gin Trp Arg Val Leu Glu Gly Pro Leu Lys Glu Glu Tyr Asn He Phe
85 90 95
Ser Lys Thr Met Lys Val Ser Pro Lys Gin Gly Gly Ser Gly Ser Val
100 105 110
Val Lys Trp Asn Leu Lys Tyr Glu Arg He Asp Glu Lys Val Ala His
115 120 125
Leu Glu Arg Leu Leu Gin Phe Phe Val Glu Cys Val Asn Glu He Asp
130 135 140
Gin Tyr Leu Leu Ser Glu Gly 145 150
(2) INFORMATION FOR SEQ ID NO: 185: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 131 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..131
(D) OTHER INFORMATION: / Ceres Seq. ID 1388501 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 185: Met Phe Ser Arg Arg Ser Gin His Ala Ser Lys Ala Thr Arg Tyr Val 1 5 10 15
Gin Gly Cys Asp Leu Leu Glu Gly Glu Trp Gly Glu Val Gly Ser He
20 25 30
Leu Leu Trp Lys Leu Thr Val Asp Gly Glu Pro Lys Val Ser Lys Asp 35 40 45
Met He Glu Ala He Asp Met Lys Met Asn Met He Gin Trp Arg Val
50 55 60
Leu Glu Gly Pro Leu Lys Glu Glu Tyr Asn He Phe Ser Lys Thr Met 65 70 75 80 Lys Val Ser Pro Lys Gin Gly Gly Ser Gly Ser Val Val Lys Trp Asn
85 90 95
Leu Lys Tyr Glu Arg He Asp Glu Lys Val Ala His Leu Glu Arg Leu
100 105 110
Leu Gin Phe Phe Val Glu Cys Val Asn Glu He Asp Gin Tyr Leu Leu 115 120 125
Ser Glu Gly
130 (2) INFORMATION FOR SEQ ID NO: 186: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 83 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..83
(D) OTHER INFORMATION: / Ceres Seq. ID 1388502 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 186: Met He Glu Ala He Asp Met Lys Met Asn Met He Gin Trp Arg Val 1 5 10 15
Leu Glu Gly Pro Leu Lys Glu Glu Tyr Asn He Phe Ser Lys Thr Met
20 25 30
Lys Val Ser Pro Lys Gin Gly Gly Ser Gly Ser Val Val Lys Trp Asn 35 40 45
Leu Lys Tyr Glu Arg He Asp Glu Lys Val Ala His Leu Glu Arg Leu
50 55 60
Leu Gin Phe Phe Val Glu Cys Val Asn Glu He Asp Gin Tyr Leu Leu 65 70 75 80 Ser Glu Gly
(2) INFORMATION FOR SEQ ID NO: 187: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 752 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..752
(D) OTHER INFORMATION: / Ceres Seq. ID 1388519
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 187: aatctcacgc gctttcatca tcttcttcct agattcgctc ctccactatt cgaaaaaatg 60 gcgaaactgg tgatgttgtt ggttctctgt atcttaccgg cgatagccat ggcggcaagg 120 aggggaaata ttggaaagaa tacaatggtg gttcaaggta gcacctactg tgacatttgc 180 aaattcggct tcgagactcc tgaatcctcc tacttcatcc ccggtgcaac ggtgaagcta 240 tcatgcaaag acaggaagac aatggaagag gtttacacag acaaagctgt atcagacaaa 300 gaaggaaagt ataagttcat tgtccacgac gatcacagag accagatgtg cgatgttttg 360 cttgtgaaaa gctcggataa aacctgctct aaaatctccg ttggacgtga gaagtctcgt 420 gtgatcttga accattacag tggcattgcc tcgcagatca gacatgctaa caacatggga 480 tttgagaaag aagtgagtga tgtgttctgc tctgctttgt ttcagaagta tatggttgat 540 gaagatgagg atgatattaa aaaccatctc taatctctct gtttaatctt atgatctgct 600 gttttcttca ttaatgagtt tccagttatg gaagagatat atttgtattt gtttgattac 660 ttatttgttg tctttagaga tgttgactct ggtgatcgga taactatctg tttgtgtaag 720 cttcttatat attgatgtgt catttccttg cc (2) INFORMATION FOR SEQ ID NO: 188: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 190 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..190
(D) OTHER INFORMATION: / Ceres Seq. ID 1388520 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 188: Asn Leu Thr Arg Phe His His Leu Leu Pro Arg Phe Ala Pro Pro Leu 1 5 10 15
Phe Glu Lys Met Ala Lys Leu Val Met Leu Leu Val Leu Cys He Leu
20 25 30
Pro Ala He Ala Met Ala Ala Arg Arg Gly Asn He Gly Lys Asn Thr
35 40 45
Met Val Val Gin Gly Ser Thr Tyr Cys Asp He Cys Lys Phe Gly Phe
50 55 60
Glu Thr Pro Glu Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu 65 70 75 80
Ser Cys Lys Asp Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala
85 90 95
Val Ser Asp Lys Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His
100 105 110
Arg Asp Gin Met Cys Asp Val Leu Leu Val Lys Ser Ser Asp Lys Thr
115 120 125
Cys Ser Lys He Ser Val Gly Arg Glu Lys Ser Arg Val He Leu Asn
130 135 140
His Tyr Ser Gly He Ala Ser Gin He Arg His Ala Asn Asn Met Gly 145 150 155 160
Phe Glu Lys Glu Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys
165 170 175
Tyr Met Val Asp Glu Asp Glu Asp Asp He Lys Asn His Leu 180 185 190
(2) INFORMATION FOR SEQ ID NO: 189: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 171 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..171
(D) OTHER INFORMATION: / Ceres Seq. ID 1388521 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 189: Met Ala Lys Leu Val Met Leu Leu Val Leu Cys He Leu Pro Ala He 1 5 10 15
Ala Met Ala Ala Arg Arg Gly Asn He Gly Lys Asn Thr Met Val Val
20 25 30
Gin Gly Ser Thr Tyr Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro 35 40 45
Glu Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys
50 55 60
Asp Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp 65 70 75 80
Lys Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His Arg Asp Gin
85 90 95
Met Cys Asp Val Leu Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys 100 105 110 He Ser Val Gly Arg Glu Lys Ser Arg Val He Leu Asn His Tyr Ser 115 120 125
Gly He Ala Ser Gin He Arg His Ala Asn Asn Met Gly Phe Glu Lys
130 135 140
Glu Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val 145 150 155 160
Asp Glu Asp Glu Asp Asp He Lys Asn His Leu
165 170
(2) INFORMATION FOR SEQ ID NO: 190: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 166 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..166
(D) OTHER INFORMATION: / Ceres Seq. ID 1388522 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 190: Met Leu Leu Val Leu Cys He Leu Pro Ala He Ala Met Ala Ala Arg 1 5 10 15
Arg Gly Asn He Gly Lys Asn Thr Met Val Val Gin Gly Ser Thr Tyr
20 25 30
Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro Glu Ser Ser Tyr Phe 35 40 45
He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys Asp Arg Lys Thr Met
50 55 60
Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp Lys Glu Gly Lys Tyr 65 70 75 80 Lys Phe He Val His Asp Asp His Arg Asp Gin Met Cys Asp Val Leu
85 90 95
Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys He Ser Val Gly Arg
100 105 110
Glu Lys Ser Arg Val He Leu Asn His Tyr Ser Gly He Ala Ser Gin 115 120 125
He Arg His Ala Asn Asn Met Gly Phe Glu Lys Glu Val Ser Asp Val
130 135 140
Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val Asp Glu Asp Glu Asp 145 150 155 160 Asp He Lys Asn His Leu
165 (2) INFORMATION FOR SEQ ID NO: 191: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 658 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..658
(D) OTHER INFORMATION: / Ceres Seq. ID 1388563 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 191: aagaagtttt ctctacatcc acaaaagaaa aaaagtttcc caaaaaacaa aaacttacac 60 aagtttagat atggatcttg aattactaca agatttgtcc aaattcaatt tcccaacacc 120 catcaagatc cgatccaaaa cctcaaaaga caaagaagga cgaaggtgat gacgacgaag 180 atgacctcag ctgcagcaca cccacatccc aagaacacaa gattcccgcc gtcatagact 240 ctccacctcc tccgccgaga aaaccccggc caccaccgtc agcaccgtcg gctacggcgg 300 ctctgatgat cagatcgtgc aagaggaagc ttttagtgtc gacttgtgag ataatcatga 360 atcgggaaga gattgaccgt ttcttctcct ccgtctacaa tgagacgtcg actacggcta 420 aacggcggag aagttaccct tattgttctc gaagatgagg cttaattcaa tatttacatt 480 tttttacagt tttactggaa atattgtgaa attaattatc tgttggtgtt cggttttaaa 540 tatttttaat ttagttatga atatggatgg ataattttct gcaaccgcgc atattaattt 600 cgcatggagg ggtcgatgtt gtaaattgag taataaatga aatttaattc caattgcc (2) INFORMATION FOR SEQ ID NO: 192: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 55 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..55 (D) OTHER INFORMATION: / Ceres Seq. ID 1388564
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 192: Arg Ser Phe Leu Tyr He His Lys Arg Lys Lys Val Ser Gin Lys Thr 1 5 10 15
Lys Thr Tyr Thr Ser Leu Asp Met Asp Leu Glu Leu Leu Gin Asp Leu
20 25 30
Ser Lys Phe Asn Phe Pro Thr Pro He Lys He Arg Ser Lys Thr Ser
35 40 45
Lys Asp Lys Glu Gly Arg Arg 50 55
(2) INFORMATION FOR SEQ ID NO: 193:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 50 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..50
(D) OTHER INFORMATION: / Ceres Seq. ID 1388565 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 193: Met He Arg Ser Cys Lys Arg Lys Leu Leu Val Ser Thr Cys Glu He 1 5 10 15
He Met Asn Arg Glu Glu He Asp Arg Phe Phe Ser Ser Val Tyr Asn
20 25 30
Glu Thr Ser Thr Thr Ala Lys Arg Arg Arg Ser Tyr Pro Tyr Cys Ser
35 40 45
Arg Arg
50 (2) INFORMATION FOR SEQ ID NO: 194:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 39 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..39 ( D) OTHER INFORMATION : / Ceres Seq . ID 1388566 ( xi ) SEQUENCE DESCRIPTION : SEQ ID NO : 194 : Met Arg Leu Asn Ser He Phe Thr Phe Phe Tyr Ser Phe Thr Gly Asn 1 5 10 15
He Val Lys Leu He He Cys Trp Cys Ser Val Leu Asn He Phe Asn
20 25 30
Leu Val Met Asn Met Asp Gly
35 ( 2 ) INFORMATION FOR SEQ ID NO : 195 :
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 866 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..866 (D) OTHER INFORMATION: / Ceres Seq. ID 1388793
(xi! SEQUENCE DESCRIPTION: SEQ ID NO: 195: aacggtgtgg gctaatctca cgcgctttca tcatcttctt cctagattcg ctcctccact 60 gtcttaaatt tcactatctt cttcttcatt ttccttcctt ctcacttcaa atccataatc 120 gctctacttc tctctctctc tagattcgaa aaaatggcga aactggtgat gttgttggtt 180 ctctgtatct taccggcgat agccatggcg gcaaggaggg gaaatattgg aaagaataca 240 atggtggttc aaggtagcac ctactgtgac atttgcaaat tcggcttcga gactcctgaa 300 tcctcctact tcatccccgg tgcaacggtg aagctatcat gcaaagacag gaagacaatg 360 gaagaggttt acacagacaa agctgtatca gacaaagaag gaaagtataa gttcattgtc 420 cacgacgatc acagagacca gatgtgcgat gttttgcttg tgaaaagctc ggataaaacc 480 tgctctaaaa tctccgttgg acgtgagaag tctcgtgtga tcttgaacca ttacagtggc 540 attgcctcgc agatcagaca tgctaacaac atgggatttg agaaagaagt gagtgatgtg 600 ttctgctctg ctttgtttca gaagtatatg gttgatgaag atgaggatga tattaaaaac 660 catctctaat ctctctgttt aatcttatga tctgctgttt tcttcattaa tgagtttcga 720 gttatggaag agatatattt gtatttgttt gattacttat ttgttgtctt tagagatgtt 780 gactctggtg atcggataac tatctgtttg tgtaagcttc ttatatattg atatgtcatt 840 tccttgctta ggaagtgtct tttatt (2) INFORMATION FOR SEQ ID NO: 196:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 171 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..171
(D) OTHER INFORMATION: / Ceres Seq. ID 1388794
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 196:
Met Ala Lys Leu Val Met Leu Leu Val Leu Cys He Leu Pro Ala He
10 15
Ala Met Ala Ala Arg Arg Gly Asn He Gly Lys Asn Thr Met Val Val 20 25 30
Gin Gly Ser Thr Tyr Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro
35 40 45
Glu Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys 50 55 60
Asp Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp 65 70 75 80
Lys Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His Arg Asp Gin 85 90 95
Met Cys Asp Val Leu Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys 100 105 110
He Ser Val Gly Arg Glu Lys Ser Arg Val He Leu Asn His Tyr Ser 115 120 125
Gly He Ala Ser Gin He Arg His Ala Asn Asn Met Gly Phe Glu Lys
130 135 140
Glu Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val 145 150 155 160
Asp Glu Asp Glu Asp Asp He Lys Asn His Leu
165 170
(2) INFORMATION FOR SEQ ID NO: 197: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 166 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..166
(D) OTHER INFORMATION: / Ceres Seq. ID 1388795 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 197: Met Leu Leu Val Leu Cys He Leu Pro Ala He Ala Met Ala Ala Arg 1 5 10 15
Arg Gly Asn He Gly Lys Asn Thr Met Val Val Gin Gly Ser Thr Tyr
20 25 30
Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro Glu Ser Ser Tyr Phe 35 40 45
He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys Asp Arg Lys Thr Met
50 55 60
Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp Lys Glu Gly Lys Tyr 65 70 75 80 Lys Phe He Val His Asp Asp His Arg Asp Gin Met Cys Asp Val Leu
85 90 95
Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys He Ser Val Gly Arg
100 105 110
Glu Lys Ser Arg Val He Leu Asn His Tyr Ser Gly He Ala Ser Gin 115 120 125
He Arg His Ala Asn Asn Met Gly Phe Glu Lys Glu Val Ser Asp Val
130 135 140
Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val Asp Glu Asp Glu Asp 145 150 155 160 Asp He Lys Asn His Leu
165 (2) INFORMATION FOR SEQ ID NO: 198: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 154 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..154
(D) OTHER INFORMATION: / Ceres Seq. ID 1388796 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 198: Met Ala Ala Arg Arg Gly Asn He Gly Lys Asn Thr Met Val Val Gin 1 5 10 15
Gly Ser Thr Tyr Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro Glu
20 25 30
Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys Asp 35 40 45 Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp Lys 50 55 60
Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His Arg Asp Gin Met 65 70 75 80
Cys Asp Val Leu Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys He
85 90 95
Ser Val Gly Arg Glu Lys Ser Arg Val He Leu Asn His Tyr Ser Gly 100 105 110
He Ala Ser Gin He Arg His Ala Asn Asn Met Gly Phe Glu Lys Glu
115 120 125
Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val Asp
130 135 140
Glu Asp Glu Asp Asp He Lys Asn His Leu 145 150
(2) INFORMATION FOR SEQ ID NO: 199: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 533 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..533
(D) OTHER INFORMATION: / Ceres Seq. ID 139204: (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 199: aaccataaca caaatacacc aaaaaaaaaa aaacagaaag taacatgaga tctctcttat 60 tagccgtgtg cctggttctt gctttacact gcggtgaagc agccgtgtct tgcaacacgg 120 tgattgcgga tctttaccct tgcttatcct acgtgactca gggcggaccg gtcccaaccc 180 tctgctgcaa cggtctcaca acactcaaga gtcaggctca aacttctgtg gaccgtcagg 240 gggtctgtcg ttgcatcaaa tctgctattg gaggactcac tctctctcct agaaccatcc 300 aaaatgcttt ggaattgcct tctaaatgtg gtgtcgatct cccttacaag ttcagccctt 360 ccactgactg cgacagtatc cagtgagaca agcagaaaat cttaaaggaa gctactacaa 420 gaactataat aacctaataa ttaataaatg agggcattgg tttgctagtt gctaattgat 480 cagtgatgta ttgtcatttt gaatgttcta atatcagcag gcacttatct ctg
(2) INFORMATION FOR SEQ ID NO: 200: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 113 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..113
(D) OTHER INFORMATION: / Ceres Seq. ID 1392042
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 200:
Met Arg Ser Leu Leu Leu Ala Val Cys Leu Val Leu Ala Leu His Cys
1 5 10 15
Gly Glu Ala Ala Val Ser Cys Asn Thr Val He Ala Asp Leu Tyr Pro
20 25 30
Cys Leu Ser Tyr Val Thr Gin Gly Gly Pro Val Pro Thr Leu Cys Cys
35 40 45
Asn Gly Leu Thr Thr Leu Lys Ser Gin Ala Gin Thr Ser Val Asp Arg
50 55 60
Gin Gly Val Cys Arg Cys He Lys Ser Ala He Gly Gly Leu Thr Leu 65 70 75 80
Ser Pro Arg Thr He Gin Asn Ala Leu Glu Leu Pro Ser Lys Cys Gly
85 90 95
Val Asp Leu Pro Tyr Lys Phe Ser Pro Ser Thr Asp Cys Asp Ser He
100 105 110
Gin
(2) INFORMATION FOR SEQ ID NO: 201: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1028 base pairs
( B ) TYPE: nucleic acid
(C ) STRANDEDNESS: single
( D) TOPOLOGY: linear ( ii ) MOLECULE TYPE : DNA (genomic) ( ix ) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..1028 (D) OTHER INFORMATION: / Ceres Seq. ID 1393342
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 201: aatatgtcct taattgctct tatcggagaa ggcttactct gtttttcagg cgaactctgt 60 ttatcttctc cgagctcgta cgagaatatt cgtaaaggtt tcttgtgagc ttaaacgatg 120 agtacccttg agaccacaag agctgagctt ggtctggtag ttgtgtattt gaataaagcg 180 gaggcgagag acaagatttg tcgagctatt caatatggtt ccaagttctt gagtgatggc 240 caacctggca ctgctcaaaa tgtcgacaag aacaccagct tggctaggaa agttttccgt 300 ctcttcaagt ttgtaaatga tcttcatgct ctcattagcc ctgttcccaa agggactcca 360 ctcccgcttg ttctgctcgg aaagtctaaa aacgcgttgc tgtcaacgtt cttgttccta 420 gatcaaattg tgtggcttgg caggactggg atttacaagg acaaagaacg tgctgagatt 480 cttggacgta tatcactttt ctgttggatg ggttcttcgg tttgcacatc cttggttgag 540 gttggggagc ttggtaggct gtcagcatca attaagaagt tagaaaaaga gatagggaac 600 aaggataaac accagaatga gcaataccgt gcaaaagtag agaaatcaaa cgagaggtca 660 ttggctctga tcaaagcagg gatggatgta gttgttgctt tcggattgct tcaattggct 720 ccaaagaaag tcactccccg agtcacaggt gctttcggat tcgcctcatc acttatctct 780 tgttatcagc tattgccgtc acatcccaag tccaagatgg tctgataaaa gggaaacaag 840 gaaaggcgaa ctagtttcat tgtccacatg ttccatatat agtttgtgtc tgttttacta 900 ttacttggtg ttaaatttgt cttgcttgac tactttaatg tttgtgttag attctatggt 960 atataagata atgataaaca ttgcagtctc tgtagaataa taagaacaga taagcattac 1020 gaggtgtc
(2) INFORMATION FOR SEQ ID NO: 202: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 235 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..235
(D) OTHER INFORMATION: / c .eres ; Seq. ID 13≤ )3342i
( (xxii)) SEQUENCE DESCRIPTION: SEQ ID NC ):202 ) »
Met Ser Thr Leu Glu Thr Thr Arg Ala Glu Leu Gly Leu Val Val Val 1 5 10 15
Tyr Leu Asn Lys Ala Glu Ala Arg Asp Lys He Cys Arg Ala He Gin 20 25 30
Tyr Gly Ser Lys Phe Leu Ser Asp Gly Gin Pro Gly Thr Ala Gin Asn 35 40 45
Val Asp Lys Asn Thr Ser Leu Ala Arg Lys Val Phe Arg Leu Phe Lys 50 55 60
Phe Val Asn Asp Leu His Ala Leu He Ser Pro Val Pro Lys Gly Thr
65 70 75 80
Pro Leu Pro Leu Val Leu Leu Gly Lys Ser Lys Asn Ala Leu Leu Ser 85 90 95
Thr Phe Leu Phe Leu Asp Gin He Val Trp Leu Gly Arg Thr Gly He 100 105 110
Tyr Lys Asp Lys Glu Arg Ala Glu He Leu Gly Arg He Ser Leu Phe 115 120 125
Cys Trp Met Gly Ser Ser Val Cys Thr Ser Leu Val Glu Val Gly Glu 130 135 140
Leu Gly Arg Leu Ser Ala Ser He Lys Lys Leu Glu Lys Glu He Gly 145 150 155 160
Asn Lys Asp Lys His Gin Asn Glu Gin Tyr Arg Ala Lys Val Glu Lys 165 170 175 Ser Asn Glu Arg Ser Leu Ala Leu He Lys Ala Gly Met Asp Val Val
180 185 190
Val Ala Phe Gly Leu Leu Gin Leu Ala Pro Lys Lys Val Thr Pro Arg
195 200 205
Val Thr Gly Ala Phe Gly Phe Ala Ser Ser Leu He Ser Cys Tyr Gin
210 215 220
Leu Leu Pro Ser His Pro Lys Ser Lys Met Val 225 230 235
(2) INFORMATION FOR SEQ ID NO:203: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 653 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..653
(D) OTHER INFORMATION: / Ceres Seq. ID 1393556 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:203: tcttcccaat cccaacagct tcatcgtttt atcttccaat caaagcagct caaatcaagc 60 tcgcaaagat gatgcacatg accttctact ggggaatcaa agccacaatt ctcttcgatt 120 tctggaaaac tgactcatgg cttagttaca tcctcacttt aatcgcttgc ttcgtcttct 180 ccgctttcta tcaatacctc gagaatcgcc gcatccaatt caaatccctt tcttcctccc 240 gtcgtgctcc tccaccgcct cgctcttcct ccggcgtctc cgcgcctctt atccctaaat 300 ccggtaccag atccgccgct aaagctgctt cggttcttct tttcggcgtc aacgcagcga 360 tcggttactt gctgatgctt gcagctatgt ctttcaacgg aggtgttttc atcgcgattg 420 tcgtcggatt aaccgccgga tacgctgttt ttagatctga tgacggcggt gctgataccg 480 ccacggatga tccatgtcca tgtgcttgat aatgattgat aataaaatca aaatcggaaa 540 aatctcaaaa aaggtgtgtt tgataattga tgtttgtatt gttgtttgtt tctgtatgat 600 tagttgcttt gtaacaaaat aatccaatct aaatgtgttt cttgagtata tgc (2) INFORMATION FOR SEQ ID NO: 204:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 168 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE peptide (ix) FEATURE :
(A) NAME/KEY peptide
(B) LOCATION 1..168
(D) OTHER INFORMATION: / Ceres Seq. ID 1393557
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 204:
Phe Pro He Pro Thr Ala Ser Ser Phe Tyr Leu Pro He Lys Ala Ala
1 5 10 15
Gin He Lys Leu Ala Lys Met Met His Met Thr Phe Tyr Trp Gly He
20 25 30
Lys Ala Thr He Leu Phe Asp Phe Trp Lys Thr Asp Ser Trp Leu Ser
35 40 45
Tyr He Leu Thr Leu He Ala Cys Phe Val Phe Ser Ala Phe Tyr Gin
50 55 60
Tyr Leu Glu Asn Arg Arg He Gin Phe Lys Ser Leu Ser Ser Ser Arg 65 70 75 80
Arg Ala Pro Pro Pro Pro Arg Ser Ser Ser Gly Val Ser Ala Pro Leu
85 90 95
He Pro Lys Ser Gly Thr Arg Ser Ala Ala Lys Ala Ala Ser Val Leu
100 105 110
Leu Phe Gly Val Asn Ala Ala He Gly Tyr Leu Leu Met Leu Ala Ala
115 120 125
Met Ser Phe Asn Gly Gly Val Phe He Ala He Val Val Gly Leu Thr
130 135 140
Ala Gly Tyr Ala Val Phe Arg Ser Asp Asp Gly Gly Ala Asp Thr Ala 145 150 155 160
Thr Asp Asp Pro Cys Pro Cys Ala
165 (2) INFORMATION FOR SEQ ID NO: 205: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 146 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..146
(D) OTHER INFORMATION: / Ceres Seq. ID 1393558 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 205:
Met Met His Met Thr Phe Tyr Trp Gly He Lys Ala Thr He Leu Phe 1 5 10 15
Asp Phe Trp Lys Thr Asp Ser Trp Leu Ser Tyr He Leu Thr Leu He 20 25 30 Ala Cys Phe Val Phe Ser Ala Phe Tyr Gin Tyr Leu Glu Asn Arg Arg 35 40 45
He Gin Phe Lys Ser Leu Ser Ser Ser Arg Arg Ala Pro Pro Pro Pro
50 55 60
Arg Ser Ser Ser Gly Val Ser Ala Pro Leu He Pro Lys Ser Gly Thr 65 70 75 80
Arg Ser Ala Ala Lys Ala Ala Ser Val Leu Leu Phe Gly Val Asn Ala
85 90 95
Ala He Gly Tyr Leu Leu Met Leu Ala Ala Met Ser Phe Asn Gly Gly 100 105 110 Val Phe He Ala He Val Val Gly Leu Thr Ala Gly Tyr Ala Val Phe 115 120 125
Arg Ser Asp Asp Gly Gly Ala Asp Thr Ala Thr Asp Asp Pro Cys Pro
130 135 140
Cys Ala 145
(2) INFORMATION FOR SEQ ID NO:206: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 145 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..145
(D) OTHER INFORMATION: / Ceres Seq. ID 1393559 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 206: Met His Met Thr Phe Tyr Trp Gly He Lys Ala Thr He Leu Phe Asp 1 5 10 15 Phe Trp Lys Thr Asp Ser Trp Leu Ser Tyr He Leu Thr Leu He Ala 20 25 30
Cys Phe Val Phe Ser Ala Phe Tyr Gin Tyr Leu Glu Asn Arg Arg He
35 40 45
Gin Phe Lys Ser Leu Ser Ser Ser Arg Arg Ala Pro Pro Pro Pro Arg 50 55 60
Ser Ser Ser Gly Val Ser Ala Pro Leu He Pro Lys Ser Gly Thr Arg 65 70 75 80
Ser Ala Ala Lys Ala Ala Ser Val Leu Leu Phe Gly Val Asn Ala Ala 85 90 95 He Gly Tyr Leu Leu Met Leu Ala Ala Met Ser Phe Asn Gly Gly Val 100 105 110
Phe He Ala He Val Val Gly Leu Thr Ala Gly Tyr Ala Val Phe Arg 115 120 125
Ser Asp Asp Gly Gly Ala Asp Thr Ala Thr Asp Asp Pro Cys Pro Cys
130 135 140
Ala 145
(2) INFORMATION FOR SEQ ID NO: 207: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 525 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..525
(D) OTHER INFORMATION: / Ceres Seq. ID 1396782
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 207: atgattttta cagacgagag gagacggcga caatggcgaa tttgatgatg agattaccaa 60 ttagcttgag aagcttctct gtttcagctt cttcatccaa cggttcgccg ccggtgatcg 120 gaggatctag cggcggtgta ggaccgatga ttgtggaatt accgttggag aagatacgaa 180 gaccgttgat gcgaaccaga tccaacgatc agaacaaagt gaaagagctt atggatagta 240 tccgtcaaat cggtcttcaa gttccgattg atgtgattga agttgatgga acttactatg 300 ggttctcggg atgtcacaga tacgaggcgc atcagaagct aggtcttcca acaatacgtt 360 gcaaaatacg taaaggaaca aaggaaacat taaggcatca tcttcgctga agagagtttt 420 acttttatgt atattgtttg tatgatagga actcgagtat gtgtatgaaa gttaagaata 480 agaactttgt acaactttgt gatagattta gtgactggat tctgc (2) INFORMATION FOR SEQ ID NO: 208: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 135 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
( (iiii)) MOLECULE TYPE: pept .ide ((iixx)) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..135
(D) OTHER INFORMATION: / Ceres ; Seq. ID 1396782 .
( (xxii)) SEQUENCE DESCRIPTION: SEQ ID NO:20£ I:
Asp Phe Tyr Arg Arg Glu Glu Thr Ala Thr Met Ala Asn Leu Met Met 1 5 10 15
Arg Leu Pro He Ser Leu Arg Ser Phe Ser Val Ser Ala Ser Ser Ser 20 25 30
Asn Gly Ser Pro Pro Val He Gly Gly Ser Ser Gly Gly Val Gly Pro 35 40 45
Met He Val Glu Leu Pro Leu Glu Lys He Arg Arg Pro Leu Met Arg 50 55 60
Thr Arg Ser Asn Asp Gin Asn Lys Val Lys Glu Leu Met Asp Ser He 65 70 75 80
Arg Gin He Gly Leu Gin Val Pro He Asp Val He Glu Val Asp Gly 85 90 95
Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg Tyr Glu Ala His Gin Lys 100 105 110
Leu Gly Leu Pro Thr He Arg Cys Lys He Arg Lys Gly Thr Lys Glu 115 120 125
Thr Leu Arg His His Leu Arg 130 135
(2) INFORMATION FOR SEQ ID NO:209: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 125 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..125 (D) OTHER INFORMATION:- / Ceres Seq. ID 1396784
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:209: Met Ala Asn Leu Met Met Arg Leu Pro He Ser Leu Arg Ser Phe Ser 1 5 10 15
Val Ser Ala Ser Ser Ser Asn Gly Ser Pro Pro Val He Gly Gly Ser 20 25 30
Ser Gly Gly Val Gly Pro Met He Val Glu Leu Pro Leu Glu Lys He
35 40 45
Arg Arg Pro Leu Met Arg Thr Arg Ser Asn Asp Gin Asn Lys Val Lys 50 55 60 Glu Leu Met Asp Ser He Arg Gin He Gly Leu Gin Val Pro He Asp 65 70 75 80
Val He Glu Val Asp Gly Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg
85 90 95
Tyr Glu Ala His Gin Lys Leu Gly Leu Pro Thr He Arg Cys Lys He 100 105 110
Arg Lys Gly Thr Lys Glu Thr Leu Arg His His Leu Arg 115 120 125
(2) INFORMATION FOR SEQ ID NO:210: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 121 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..121
(D) OTHER INFORMATION: / Ceres Seq. ID 1396785 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:210: Met Met Arg Leu Pro He Ser Leu Arg Ser Phe Ser Val Ser Ala Ser 1 5 10 15
Ser Ser Asn Gly Ser Pro Pro Val He Gly Gly Ser Ser Gly Gly Val
20 25 30
Gly Pro Met He Val Glu Leu Pro Leu Glu Lys He Arg Arg Pro Leu 35 40 45
Met Arg Thr Arg Ser Asn Asp Gin Asn Lys Val Lys Glu Leu Met Asp
50 55 60
Ser He Arg Gin He Gly Leu Gin Val Pro He Asp Val He Glu Val 65 70 75 80 Asp Gly Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg Tyr Glu Ala His
85 90 95
Gin Lys Leu Gly Leu Pro Thr He Arg Cys Lys He Arg Lys Gly Thr
100 105 110
Lys Glu Thr Leu Arg His His Leu Arg 115 120
(2) INFORMATION FOR SEQ ID NO: 211: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 939 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..939
(D) OTHER INFORMATION: / Ceres Seq. ID 1396802 (xi) SEQUENCE DESCRIPTION: SEQ ID N0.211: ataacaaacc agggtcaggg ttttatcttc catattcttt tcccactgat tcttacaatc 60 gatctaaggg aatctacgaa ctgtttggta atttctggtg ggaaaagtct tgatcttgct 120 gtttggtttg gagtaatggt gagtgcttgg tttgttgttg gctcaccggt gatggactct 180 tcgagcagtc catgtttatg tctggatgct cacacgacgg gtaccatcag gaggaagaag 240 atccttggca aagcaagaaa tctggaatta ggaagctctt tcactggctc acgcattgtt 300 tttaggcttt ctccgaagcg tgtatcgaga attgcgaatc gaaagagcaa aaagctcttg 360 attgtgaatg aggatgttgc tggtaattac gacgatacct tcggtgatgt acaaaagcaa 420 attgttaatt attttacata caaagctgtg aggacggttc ttcatcagct gtacgaaatg 480 aatcctcctc aatacacttg gttctataat catatcataa caaacagacc gacggatggc 540 aaacgtttcc tccgtgccct cggcaaggag agtcaggagc ttgcagaaag agtgatgatc 600 acgcgtcttc acttgtatgg caaatggatc aagaaatgcg accatgggaa gatataccag 660 gaaatatcgg atgaaaactt ggcgttgatg cgtgaacgcc tgatggagac cgtgatatgg 720 ccttccgatg acacaaactc aaggtaatag gctgaagaag acagcgcaca ccacagcaca 780 acatttgctt tgtcaatttg cttctcagtt tttaggactt cgagtttttt agtttgatta 840 catattacta tagtgaaaga gcagtgtgta tatgatgtct attcttggca tgtactatat 900 gatattaggg gcaaaaaaca acacccttct tgtgctcct (2) INFORMATION FOR SEQ ID NO: 212: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 248 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..248 (D) OTHER INFORMATION: / Ceres Seq. ID 1396803
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 212: He Thr Asn Gin Gly Gin Gly Phe He Phe His He Leu Phe Pro Leu 1 5 10 15
He Leu Thr He Asp Leu Arg Glu Ser Thr Asn Cys Leu Val He Ser
20 25 30
Gly Gly Lys Ser Leu Asp Leu Ala Val Trp Phe Gly Val Met Val Ser
35 40 45
Ala Trp Phe Val Val Gly Ser Pro Val Met Asp Ser Ser Ser Ser Pro
50 55 60
Cys Leu Cys Leu Asp Ala His Thr Thr Gly Thr He Arg Arg Lys Lys 65 70 75 80
He Leu Gly Lys Ala Arg Asn Leu Glu Leu Gly Ser Ser Phe Thr Gly
85 90 95
Ser Arg He Val Phe Arg Leu Ser Pro Lys Arg Val Ser Arg He Ala
100 105 110
Asn Arg Lys Ser Lys Lys Leu Leu He Val Asn Glu Asp Val Ala Gly
115 120 125
Asn Tyr Asp Asp Thr Phe Gly Asp Val Gin Lys Gin He Val Asn Tyr
130 135 140
Phe Thr Tyr Lys Ala Val Arg Thr Val Leu His Gin Leu Tyr Glu Met 145 150 155 160
Asn Pro Pro Gin Tyr Thr Trp Phe Tyr Asn His He He Thr Asn Arg
165 170 175
Pro Thr Asp Gly Lys Arg Phe Leu Arg Ala Leu Gly Lys Glu Ser Gin
180 185 190
Glu Leu Ala Glu Arg Val Met He Thr Arg Leu His Leu Tyr Gly Lys
195 200 205
Trp He Lys Lys Cys Asp His Gly Lys He Tyr Gin Glu He Ser Asp
210 215 220
Glu Asn Leu Ala Leu Met Arg Glu Arg Leu Met Glu Thr Val He Trp 225 230 235 240
Pro Ser Asp Asp Thr Asn Ser Arg
245 (2) INFORMATION FOR SEQ ID NO: 213: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 203 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..203
(D) OTHER INFORMATION: / Ceres Seq. ID 1396804 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 213:
Met Val Ser Ala Trp Phe Val Val Gly Ser Pro Val Met Asp Ser Ser 1 5 10 15
Ser Ser Pro Cys Leu Cys Leu Asp Ala His Thr Thr Gly Thr He Arg 20 25 30 Arg Lys Lys He Leu Gly Lys Ala Arg Asn Leu Glu Leu Gly Ser Ser 35 40 45
Phe Thr Gly Ser Arg He Val Phe Arg Leu Ser Pro Lys Arg Val Ser
50 55 60
Arg He Ala Asn Arg Lys Ser Lys Lys Leu Leu He Val Asn Glu Asp 65 70 75 80
Val Ala Gly Asn Tyr Asp Asp Thr Phe Gly Asp Val Gin Lys Gin He
85 90 95
Val Asn Tyr Phe Thr Tyr Lys Ala Val Arg Thr Val Leu His Gin Leu 100 105 110 Tyr Glu Met Asn Pro Pro Gin Tyr Thr Trp Phe Tyr Asn His He He 115 120 125
Thr Asn Arg Pro Thr Asp Gly Lys Arg Phe Leu Arg Ala Leu Gly Lys
130 135 140
Glu Ser Gin Glu Leu Ala Glu Arg Val Met He Thr Arg Leu His Leu 145 150 155 160
Tyr Gly Lys Trp He Lys Lys Cys Asp His Gly Lys He Tyr Gin Glu
165 170 175
He Ser Asp Glu Asn Leu Ala Leu Met Arg Glu Arg Leu Met Glu Thr 180 185 190 Val He Trp Pro Ser Asp Asp Thr Asn Ser Arg 195 200
(2) INFORMATION FOR SEQ ID NO: 214: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 191 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..191
(D) OTHER INFORMATION: / Ceres Seq. ID 1396805 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 214: Met Asp Ser Ser Ser Ser Pro Cys Leu Cys Leu Asp Ala His Thr Thr 1 5 10 15
Gly Thr He Arg Arg Lys Lys He Leu Gly Lys Ala Arg Asn Leu Glu
20 25 30
Leu Gly Ser Ser Phe Thr Gly Ser Arg He Val Phe Arg Leu Ser Pro 35 40 45 Lys Arg Val Ser Arg He Ala Asn Arg Lys Ser Lys Lys Leu Leu He 50 55 60
Val Asn Glu Asp Val Ala Gly Asn Tyr Asp Asp Thr Phe Gly Asp Val 65 70 75 80
Gin Lys Gin He Val Asn Tyr Phe Thr Tyr Lys Ala Val Arg Thr Val 85 90 95
Leu His Gin Leu Tyr Glu Met Asn Pro Pro Gin Tyr Thr Trp Phe Tyr 100 105 110 Asn His He He Thr Asn Arg Pro Thr Asp Gly Lys Arg Phe Leu Arg
115 120 125
Ala Leu Gly Lys Glu Ser Gin Glu Leu Ala Glu Arg Val Met He Thr
130 135 140
Arg Leu His Leu Tyr Gly Lys Trp He Lys Lys Cys Asp His Gly Lys 145 150 155 160 He Tyr Gin Glu He Ser Asp Glu Asn Leu Ala Leu Met Arg Glu Arg
165 170 175
Leu Met Glu Thr Val He Trp Pro Ser Asp Asp Thr Asn Ser Arg
180 185 190
( 2 ) INFORMATION FOR SEQ ID NO: 215: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 753 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..753
(D) OTHER INFORMATION: / Ceres Seq ID 1397130 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 215 aaagatttgg agaaaaagtt tactaaaaaa gaatctgggg aagtaagtga gatgaaggaa 60 gaggaggaga tcggaaaacc agcgaaacca aaagccaaga aagatgttgc tcctgggagg 120 ttgattgata cctatgctgc acagtgcgat aactgtcaca agtggagggt gattgatagc 180 caggaggaat atgaagatat cagaagtaaa atgctcgagg atccttttaa ctgtcagaag 240 aaacagggca tgtcttgtga agagcctgct gatattgact acgattcttc tcggacttgg 300 gtcattgaca agcctggtct ccccaaaacg cctaaaggtt tcaagagaag cttagttctc 360 agaaaagatt actctaagat ggatacctac tactttactc ctaccgggaa gaagctcagg 420 agtcgcaatg aaatcgctgc cttcgttgaa gccaatccgg aattcaggaa cgcaccactt 480 ggagacttca atttcactgt ccccaaggtc atggaagata ctgttccccc tgatccgaag 540 cttggctctc cttttccaag cactactacc actacttcag agaagagcag tgtcaagcag 600 agccataact aatatgttct cttctccggg cctttttcta ctttctttct gctccctaaa 660 gcaatgcgtt ttgagtcttt atagatttga tgttctctaa aactgttatg atattaacat 720 ctctaagcaa aaaaatatga tcttttgtct etc
(2) INFORMATION FOR SEQ ID NO:216: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 203 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..203
(D) OTHER INFORMATION: : / Ceres Seq. ID 1397131
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 21c
Lys Asp Leu Glu Lys Lys Phe Thr Lys Lys Glu Ser Gly Glu Val Ser
1 5 10 15
Glu Met Lys Glu Glu Glu Glu He Gly Lys Pro Ala Lys Pro Lys Ala 20 25 30
Lys Lys Asp Val Ala Pro Gly Arg Leu He Asp Thr Tyr Ala Ala Gin 35 40 45
Cys Asp Asn Cys His Lys Trp Arg Val He Asp Ser Gin Glu Glu Tyr 50 55 60
Glu Asp He Arg Ser Lys Met Leu Glu Asp Pro Phe Asn Cys Gin Lys
65 70 75 80
Lys Gin Gly Met Ser Cys Glu Glu Pro Ala Asp He Asp Tyr Asp Ser 85 90 95
Ser Arg Thr Trp Val He Asp Lys Pro Gly Leu Pro Lys Thr Pro Lys 100 105 110
Gly Phe Lys Arg Ser Leu Val Leu Arg Lys Asp Tyr Ser Lys Met Asp 115 120 125
Thr Tyr Tyr Phe Thr Pro Thr Gly Lys Lys Leu Arg Ser Arg Asn Glu
130 135 140
He Ala Ala Phe Val Glu Ala Asn Pro Glu Phe Arg Asn Ala Pro Leu 145 150 155 160
Gly Asp Phe Asn Phe Thr Val Pro Lys Val Met Glu Asp Thr Val Pro
165 170 175
Pro Asp Pro Lys Leu Gly Ser Pro Phe Pro Ser Thr Thr Thr Thr Thr 180 185 190 Ser Glu Lys Ser Ser Val Lys Gin Ser His Asn 195 200
(2) INFORMATION FOR SEQ ID NO: 217: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 186 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..186
(D) OTHER INFORMATION: / Ceres Seq. ID 1397132 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 217: Met Lys Glu Glu Glu Glu He Gly Lys Pro Ala Lys Pro Lys Ala Lys 1 5 10 15
Lys Asp Val Ala Pro Gly Arg Leu He Asp Thr Tyr Ala Ala Gin Cys
20 25 30
Asp Asn Cys His Lys Trp Arg Val He Asp Ser Gin Glu Glu Tyr Glu 35 40 45 Asp He Arg Ser Lys Met Leu Glu Asp Pro Phe Asn Cys Gin Lys Lys 50 55 60
Gin Gly Met Ser Cys Glu Glu Pro Ala Asp He Asp Tyr Asp Ser Ser 65 70 75 80
Arg Thr Trp Val He Asp Lys Pro Gly Leu Pro Lys Thr Pro Lys Gly 85 90 95
Phe Lys Arg Ser Leu Val Leu Arg Lys Asp Tyr Ser Lys Met Asp Thr
100 105 110
Tyr Tyr Phe Thr Pro Thr Gly Lys Lys Leu Arg Ser Arg Asn Glu He 115 120 125 Ala Ala Phe Val Glu Ala Asn Pro Glu Phe Arg Asn Ala Pro Leu Gly 130 135 140
Asp Phe Asn Phe Thr Val Pro Lys Val Met Glu Asp Thr Val Pro Pro 145 150 155 160
Asp Pro Lys Leu Gly Ser Pro Phe Pro Ser Thr Thr Thr Thr Thr Ser 165 170 175
Glu Lys Ser Ser Val Lys Gin Ser His Asn
180 185
(2) INFORMATION FOR SEQ ID NO:218: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 133 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..133
(D) OTHER INFORMATION: / Ceres Seq. ID 1397133 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:218: Met Leu Glu Asp Pro Phe Asn Cys Gin Lys Lys Gin Gly Met Ser Cys 1 5 10 15
Glu Glu Pro Ala Asp He Asp Tyr Asp Ser Ser Arg Thr Trp Val He 20 25 30
Asp Lys Pro Gly Leu Pro Lys Thr Pro Lys Gly Phe Lys Arg Ser Leu
35 40 45
Val Leu Arg Lys Asp Tyr Ser Lys Met Asp Thr Tyr Tyr Phe Thr Pro
50 55 60
Thr Gly Lys Lys Leu Arg Ser Arg Asn Glu He Ala Ala Phe Val Glu 65 70 75 80
Ala Asn Pro Glu Phe Arg Asn Ala Pro Leu Gly Asp Phe Asn Phe Thr
85 90 95
Val Pro Lys Val Met Glu Asp Thr Val Pro Pro Asp Pro Lys Leu Gly
100 105 110
Ser Pro Phe Pro Ser Thr Thr Thr Thr Thr Ser Glu Lys Ser Ser Val
115 120 125 Lys Gin Ser His Asn 130
(2) INFORMATION FOR SEQ ID NO: 219:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 784 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..784 (D) OTHER INFORMATION: / Ceres Seq. ID 1398004
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 219: actcatcaac caaaacaaaa cataaaaaaa caagtggaag ctttaaaacg agagggagag 60 agcaaaaatg gcgacgtcgg gaacgtacgt gacggaagtt ccgctaaaag gatcggccga 120 gaaatactac aagaggtgga agaacgagaa ccatgtcttc cctgatgcta tcggccacca 180 catccaaaat gttaccgttc acgaaggcga acatgactct cacgggtcta tcaggagttg 240 gaactacaca tgggatggaa aggaggaggt gttcaaggag agaagagaga tagacgatga 300 gaccaaaacg ttgacgttaa gaggacttga gggtcacgtg atggagcagc tcaaagtgta 360 cgacgtcgtc taccaattca ttcccaaatc tgaggatacc tgcatcggca aaatcacttt 420 aatatgggag aagcgcaacg atgattcccc agaaccaagc ggctacataa aattcgtcaa 480 gagcttggtt gctgacatgg gaaaccacgt tagcaaaact taatcatcat tcccacagtc 540 gtcgtcgtcg tcatcatcat catcatcatc atcatcatca tcatcatcat catcatcatc 600 atcatcatca ctatctcgat ttataagtta agatgttttc agtataataa atggggtctt 660 gtggatcgtt catttctatg tgtaaaccgt ttggttctgt atgatgcttc gatatattgt 720 tatgttcatg atcatatgtc gggttcgata taatgattct taagattaat ttactacaca 780 tttc
(2) INFORMATION FOR SEQ ID NO: 220: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..151
(D) OTHER INFORMATION: / Ceres Seq. ID 1398005
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 220:
Met Ala Thr Ser Gly Thr Tyr Val Thr Glu Val Pro Leu Lys Gly Ser
10 15
Ala Glu Lys Tyr Tyr Lys Arg Trp Lys Asn Glu Asn His Val Phe Pro
20 25 30
Asp Ala He Gly His His He Gin Asn Val Thr Val His Glu Gly Glu
35 40 45
His Asp Ser His Gly Ser He Arg Ser Trp Asn Tyr Thr Trp Asp Gly
50 55 60
Lys Glu Glu Val Phe Lys Glu Arg Arg Glu He Asp Asp Glu Thr Lys 65 70 75 80
Thr Leu Thr Leu Arg Gly Leu Glu Gly His Val Met Glu Gin Leu Lys
85 90 95
Val Tyr Asp Val Val Tyr Gin Phe He Pro Lys Ser Glu Asp Thr Cys 100 105 110
He Gly Lys He Thr Leu He Trp Glu Lys Arg Asn Asp Asp Ser Pro
115 120 125
Glu Pro Ser Gly Tyr He Lys Phe Val Lys Ser Leu Val Ala Asp Met 130 135 140 Gly Asn His Val Ser Lys Thr 145 150
(2) INFORMATION FOR SEQ ID NO: 221: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 389 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..389
(D) OTHER INFORMATION: / Ceres Seq. ID 1399370 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 221: aaaaactttt tcagagtcgg aggtttcaga cagagaggaa gaagatgaag cggacggtga 60 tggacaacgc gattcgatca tcggtggtgg tgttgggatc attggccttt ggttacttgt 120 cactggagct tggttacaag cctttccttg aaaaggctga acaatacgaa agatctcttc 180 agtcttctca acaacatcaa caacaagatg aacaagaaga agcgaggtgg gacaatagca 240 atgtcgaggg gtgggaggag aaaaggtagt cttataatcg gtttcaatac agacatatca 300 aagtgtgtaa ggaagaagaa ccttatcaaa attttcttct taatcaaccg taagttcaat 360 ctgttaacta tcaaccatgg cctgttttt
(2) INFORMATION FOR SEQ ID NO: 222: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 88 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..88
(D) OTHER INFORMATION: / Ceres Seq. ID 1399371 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:222: Lys Leu Phe Gin Ser Arg Arg Phe Gin Thr Glu Arg Lys Lys Met Lys 1 5 10 15 Arg Thr Val Met Asp Asn Ala He Arg Ser Ser Val Val Val Leu Gly 20 25 30
Ser Leu Ala Phe Gly Tyr Leu Ser Leu Glu Leu Gly Tyr Lys Pro Phe
35 40 45
Leu Glu Lys Ala Glu Gin Tyr Glu Arg Ser Leu Gin Ser Ser Gin Gin 50 55 60
His Gin Gin Gin Asp Glu Gin Glu Glu Ala Arg Trp Asp Asn Ser Asn 65 70 75 80
Val Glu Gly Trp Glu Glu Lys Arg 85 (2) INFORMATION FOR SEQ ID NO: 223: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 1399372 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 223: Met Lys Arg Thr Val Met Asp Asn Ala He Arg Ser Ser Val Val Val 1 5 10 15
Leu Gly Ser Leu Ala Phe Gly Tyr Leu Ser Leu Glu Leu Gly Tyr Lys
20 25 30
Pro Phe Leu Glu Lys Ala Glu Gin Tyr Glu Arg Ser Leu Gin Ser Ser
35 40 45
Gin Gin His Gin Gin Gin Asp Glu Gin Glu Glu Ala Arg Trp Asp Asn
50 55 60
Ser Asn Val Glu Gly Trp Glu Glu Lys Arg 65 70
(2) INFORMATION FOR SEQ ID NO: 224: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 69 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..69 (D) OTHER INFORMATION: / Ceres Seq. ID 1399373
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 224: Met Asp Asn Ala He Arg Ser Ser Val Val Val Leu Gly Ser Leu Ala 1 5 10 15
Phe Gly Tyr Leu Ser Leu Glu Leu Gly Tyr Lys Pro Phe Leu Glu Lys
20 25 30
Ala Glu Gin Tyr Glu Arg Ser Leu Gin Ser Ser Gin Gin His Gin Gin
35 40 45
Gin Asp Glu Gin Glu Glu Ala Arσ Trp Asp Asn Ser Asn Val Glu Gly
50 55 60
Trp Glu Glu Lys Arg 65
(2) INFORMATION FOR SEQ ID NO: 225: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 745 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..745
(D) OTHER INFORMATION: / Ceres Seq. ID 1425147 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:225: atttcttcgt ctctgtctcc aaaatcgaat caaaatctct aaagtttcaa tttttttgtt 60 ctgttctttt ttttttttta aagaatggct tcaatttctg caactttgcc ttcgccattg 120 ttactcacac agagaaaatc caatctcaca tcgattcaaa aactcccatt ttctctaact 180 cgaggtacga atgatctttc tccattatct cttactcgaa accctagcag catcagtctg 240 atggtgaaat ctagtggaga aagctcagat tcatcgactg atctcgacgt tgttagtacg 300 attcagaatg tttgggataa gtctgaagat aggttaggtc ttattggttt gggttttgct 360 ggtattgtag ctctttgggc atcattgaat ctcatcacgg caattgacaa attgcccgtt 420 atctcgagcg gattcgaact agttggtatc ttgttctcca cgtggttcac atatcgatat 480 ctcttgttca aaccggacag acaggagctt tcgaaaattg tcaagaaatc agtagcggat 540 atacttggcc agtgaacctt gtgtgtgtga taatacttca tctttggaag atgatttgtt 600 tgcaagtttg taaaattaca tgacagggtg gttgttgttt ctagtccaat aatgtcatgc 660 atttgaaacc tgtaaatact ttattgttgg tttttggttg tgagcaaaat caatcttttc 720 taatttcaaa gattctcttt tatgt (2) INFORMATION FOR SEQ ID NO:226: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 156 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..156 (D) OTHER INFORMATION: / Ceres Seq. ID 1425148
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:226: Met Ala Ser He Ser Ala Thr Leu Pro Ser Pro Leu Leu Leu Thr Gin 1 5 10 15
Arg Lys Ser Asn Leu Thr Ser He Gin Lys Leu Pro Phe Ser Leu Thr 20 25 30
Arg Gly Thr Asn Asp Leu Ser Pro Leu Ser Leu Thr Arg Asn Pro Ser
35 40 45
Ser He Ser Leu Met Val Lys Ser Ser Gly Glu Ser Ser Asp Ser Ser 50 55 60 Thr Asp Leu Asp Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser 65 70 75 80
Glu Asp Arg Leu Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala
85 90 95
Leu Trp Ala Ser Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val 100 105 110
He Ser Ser Gly Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe
115 120 125
Thr Tyr Arg Tyr Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys 130 135 140 He Val Lys Lys Ser Val Ala Asp He Leu Gly Gin 145 150 155
(2) INFORMATION FOR SEQ ID NO: 227: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTil: 104 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..104
(D) OTHER INFORMATION: / Ceres Seq. ID 1425149 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 227: Met Val Lys Ser Ser Gly Glu Ser Ser Asp Ser Ser Thr Asp Leu Asp 1 5 10 15
Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser Glu Asp Arg Leu
20 25 30
Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala Leu Trp Ala Ser 35 40 45 Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val He Ser Ser Gly 50 55 60
Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe Thr Tyr Arg Tyr 65 70 75 80
Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys He Val Lys Lys 85 90 95
Ser Val Ala Asp He Leu Gly Gin
100 (2) INFORMATION FOR SEQ ID NO:228: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 769 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..769
(D) OTHER INFORMATION: / Ceres Seq. ID 1441102 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:228: ccacaacaca acttcagctt taagacagct aaaactaaat acaaagaaac agagatgggt 60 ttggttacag aggaggtgag agctaaggca gagatgtaca ccggagatga gatatgtaga 120 gagaagacaa agtgtttcct caaggaaata tctatgccca atggtttatt accattgaag 180 gatatagaag aggttgggta tgacagagag tcaggtgttg tatggctgaa gcagaagaag 240 agcatcactc acaagttcac agagatagat aagcttgtct cctatggaac cgaagtcaca 300 gccattgttg agaccgggaa aatcaagaag ctcactggag tcaaagccaa ggaacttctt 360 atttgggtca ctatcaatga gatctatacc gaggaacccc ctaccaagat cacgttcaag 420 acaccgacca cactgtccag gactttcccg gtcacagctt ttatagtccc agaagaacct 480 gccaaggagg aacctgccaa agaggaacct gccaaggaga agagcagcga agccaccgag 540 gccaaggagg ctgttgcaat caaggaggct gtcgcagtca aagaggcggc ctaatcagct 600 cagcttcagc agataaaaga gacccgaatt tttaagtgta cttcaagaat ttgaacaaat 660 catggagagt tagtgtttct cactgctcta actatcatgt attatctacc taccacttgt 720 tgctgcttgt tttacctgta ataagatatc aatatcatcc tgttccact (2) INFORMATION FOR SEQ ID NO: 229: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 197 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..197
(D) OTHER INFORMATION: / Ceres Seq. ID 1441103 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 229: Pro Gin His Asn Phe Ser Phe Lys Thr Ala Lys Thr Lys T^- Lys Glu 1 5 10 15 Thr Glu Met Gly Leu Val Thr Glu Glu Val Arg Ala Lys Ala Glu Met 20 25 30
Tyr Thr Gly Asp Glu He Cys Arg Glu Lys Thr Lys Cys Phe Leu Lys
35 40 " 45
Glu He Ser Met Pro Asn Gly Leu Leu Pro Leu Lys Asp He Glu Glu 50 55 60
Val Gly Tyr Asp Arg Glu Ser Gly Val Val Trp Leu Lys Gin Lys Lys 65 70 75 80
Ser He Thr His Lys Phe Thr Glu He Asp Lys Leu Val Ser Tyr Gly 85 90 95 Thr Glu Val Thr Ala He Val Glu Thr Gly Lys He Lys Lys Leu Thr
100 105 110
Gly Val Lys Ala Lys Glu Leu Leu He Trp Val Thr He Asn Glu He
115 120 125
Tyr Thr Glu Glu Pro Pro Thr Lys He Thr Phe Lys Thr Pro Thr Thr 130 135 140
Leu Ser Arg Thr Phe Pro Val Thr Ala Phe He Val Pro Glu Glu Pro
145 150 155 160
Ala Lys Glu Glu Pro Ala Lys Glu Glu Pro Ala Lys Glu Lys Ser Ser
165 170 175 Glu Ala Thr Glu Ala Lys Glu Ala Val Ala He Lys Glu Ala Val Ala
180 185 190
Val Lys Glu Ala Ala
195 (2) INFORMATION FOR SEQ ID NO: 230: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 179 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..179
(D) OTHER INFORMATION: / Ceres Seq. ID 1441104 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 230: Met Gly Leu Val Thr Glu Glu Val Arg Ala Lys Ala Glu Met Tyr Thr 1 5 10 15
Gly Asp Glu He Cys Arg Glu Lys Thr Lys Cys Phe Leu Lys Glu He
20 25 30
Ser Met Pro Asn Gly Leu Leu Pro Leu Lys Asp He Glu Glu Val Gly 35 40 45 Tyr Asp Arg Glu Ser Gly Val Val Trp Leu Lys Gin Lys Lys Ser He 50 55 60
Thr His Lys Phe Thr Glu He Asp Lys Leu Val Ser Tyr Gly Thr Glu 65 70 75 80
Val Thr Ala He Val Glu Thr Gly Lys He Lys Lys Leu Thr Gly Val 85 90 95
Lys Ala Lys Glu Leu Leu He Trp Val Thr He Asn Glu He Tyr Thr
100 105 110
Glu Glu Pro Pro Thr Lys He Thr Phe Lys Thr Pro Thr Thr Leu Ser 115 120 125 Arg Thr Phe Pro Val Thr Ala Phe He Val Pro Glu Glu Pro Ala Lys 130 135 140
Glu Glu Pro Ala Lys Glu Glu Pro Ala Lys Glu Lys Ser Ser Glu Ala 145 150 155 160
Thr Glu Ala Lys Glu Ala Val Ala He Lys Glu Ala Val Ala Val Lys 165 170 175
Glu Ala Ala
(2) INFORMATION FOR SEQ ID NO: 231: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 166 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..166
(D) OTHER INFORMATION: / Ceres Seq. ID 1441105 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:231: Met Tyr Thr Gly Asp Glu He Cys Arg Glu Lys Thr Lys Cys Phe Leu 1 5 10 15
Lys Glu He Ser Met Pro Asn Gly Leu Leu Pro Leu Lys A_sp He Glu
20 25 30
Glu Val Gly Tyr Asp Arg Glu Ser Gly Val Val Trp Leu Lys Gin Lys 35 40 45
Lys Ser He Thr His Lys Phe Thr Glu He Asp Lys Leu Val Ser Tyr
50 55 60
Gly Thr Glu Val Thr Ala He Val Glu Thr Gly Lys He Lys Lys Leu 65 70 75 " 80 Thr Gly Val Lys Ala Lys Glu Leu Leu He Trp Val Thr He Asn Glu
85 90 95
He Tyr Thr Glu Glu Pro Pro Thr Lys He Thr Phe Lys Thr Pro Thr
100 105 110
Thr Leu Ser Arg Thr Phe Pro Val Thr Ala Phe He Val Pro Glu Glu 115 " 120 125
Pro Ala Lys Glu Glu Pro Ala Lys Glu Glu Pro Ala Lys Glu Lys Ser 130 135 140 Ser Glu Ala Thr Glu Ala Lys Glu Ala Val Ala He Lys Glu Ala Val 145 150 155 160
Ala Val Lys Glu Ala Ala 165 (2) INFORMATION FOR SEQ ID NO: 232: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 607 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..607 (D) OTHER INFORMATION: / Ceres Seq. ID 1447480
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 232: aaaatctcta aagtttcaat tttttkgttc tgttcttttt ttttttaaag aatggcttca 60 atttctgcaa ctttgccttc gccattgtta ctcacacaga gaaaatccaa tcrcacatcg 120 attcaaaaac tcccattttc tctaactcga ggcacgaatg atctttctcc attatctctt 180 actcgaaacc ctagcagcat cagtctgatg gtgaaagcta gtggagaaag ctcagattca 240 tcgactgatc tcgacgttgt tagtacgatt cagaatgttg caattgacaa attgcccgtt 300 atctcgagcg gattcgaact agttggtatc ttgttctcca cgtggttcac atatcgatat 360 ctcttgttca aaccggacag acaggagctt tcgaaaattg tcaagaaatc agragcggat 420 atacttggcc agtgaacctt gtgtgtgtga taatacttca tctttggaag atgatttgtt 480 tgcaagtttg taaaattaca tgacagggtg gttgttgttt ctagtccaat aatgtcatgc 540 atttgaaacc tgtaaatact ttattgttgg tttttggttg tgagcaaaat caatcttttc 600 taatttc
(2) INFORMATION FOR SEQ ID NO: 233: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 127 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..127
(D) OTHER INFORMATION: / Ceres Seq. ID 1447481 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:233: Met Ala Ser He Ser Ala Thr Leu Pro Ser Pro Leu Leu Leu Thr Gin 1 5 10 15
Arg Lys Ser Asn Leu Thr Ser He Gin Lys Leu Pro Phe Ser Leu Thr
20 25 30
Arg Gly Thr Asn Asp Leu Ser Pro Leu Ser Leu Thr Arg Asn Pro Ser 35 40 45
Ser He Ser Leu Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser
50 55 60
Thr Asp Leu Asp Val Val Ser Thr He Gin Asn Val Ala He Asp Lys 65 70 75 80 Leu Pro Val He Ser Ser Gly Phe Glu Leu Val Gly He Leu Phe Ser
85 90 95
Thr Trp Phe Thr Tyr Arg Tyr Leu Leu Phe Lys Pro Asp Arg Gin Glu
100 105 110
Leu Ser Lys He Val Lys Lys Ser Val Ala Asp He Leu Gly Gin 115 120 125
(2) INFORMATION FOR SEQ ID NO: 234: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 75 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide ( ix ) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..75 (D) OTHER INFORMATION: / Ceres Seq. ID 1447482
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 234:
Met V Vaall LLyyss AAllaa Ser Gly Glu Ser Ser Asp Ser Ser Thr Asp Leu Asp
1 5 10 15
Val Val Ser Thr He Gin Asn Val Ala He Asp Lys Leu Pro Val He 20 25 30
SSeerr SSeerr GGllyy PPhhee Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe Thr 35 40 45
Tyr Arg Tyr Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys He 50 55 " 60
Val Lys Lys Ser Ala Asp He Leu Gly Gin
6655 70 75
(2) INFORMATION FOR SEQ ID NO:235: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 668 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..668
(D) OTHER INFORMATION: / Ceres Seq. ID 1447577 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:235: aaaaaaaaac aaaacaaaaa attatattca agagaaaaag gaaaaaatga atttcatctc 60 cgatcaggta aagaaactct caagctcaac accagaggcc agaccacaac aagccagtcg 120 aaggaaccga aacagctaca agaccagcta ccaacgccga gctcatggca agtgccaagg 180 ttgtagctga agctgctcaa gccgcagctc gtaacgaatc agacaaactc gacaagggta 240 aagtcgccgg agcctctgct gatatcf-ag acgctgccga gaaatacggt aagttcgatg 300 aaaagagtag cactggtcag tacctcga^ agg^tgagaa gtatctcaac gactacgagt 360 cgtcacactc caccggtgct ggtggtcctc ctcctccgac gagtcaggct gagccagcaa 420 gtcagcctga gccggcggct aagaaagacg atgaagagtc tggtggtggg cttggaggtt 480 atgccaagat ggctcaaggt ttcttgaagt gatttgatct ttaattgttg ttcatcattt 540 tcgtaataat aaattaaata actagtatcg tttgtgacta gtttatgttg cttcgtttat 600 gtttatgggg agtgacgagt gagtgtaata acttctggtg atcatgaatc taatccatct 660 ttgttgtc (2) INFORMATION FOR SEQ ID NO:236: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 62 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..62 (D) OTHER INFORMATION: / Ceres Seq. ID 1447578
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 236: Lys Lys Asn Lys Thr Lys Asn Tyr He Gin Glu Lys Lys Glu Lys Met 1 5 10 15
Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro Glu 20 25 30
Ala Arg Pro Gin Gin Ala Ser Arg Arg Asn Arg Asn Ser Tyr Lys Thr
35 40 45
Ser Tyr Gin Arg Arg Ala His Gly Lys Cys Gin Gly Cys Ser 50 55 60 (2) INFORMATION FOR SEQ ID NO: 237: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii)i MOLECULE TYPE: peptide
(ix!i FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: : / Ceres Seq. ID 1447579
(xi! i SEQUENCE DESCRIPTION: SEQ . ED NO: 237:
Met Ala Ser Ala Lys Val Val Ala Glu Ala Ala Gin Ala Ala Ala Arg
1 5" 10 15
Asn Glu Ser Asp Lys Leu Asp Lys Gly Lys Val Ala Gly Ala Ser Ala 20 25 30
Asp He Leu Asp Ala Ala Glu Lys Tyr Gly Lys Phe Asp Glu Lys Ser 35 40 45
Ser Thr Gly Gin Tyr Leu Asp Lys Ala Glu Lys Tyr Leu A.sn A.sp Tyr 50 55 60
Glu Ser Ser His Ser Thr Gly Ala Gly Gly Pro Pro Pro Pro Thr Ser
65 70 75 80
Gin Ala Glu Pro Ala Ser Gin Pro Glu Pro Ala Ala Lys Lys Asp Asp 85 90 95
Glu Glu Ser Gly Gly Gly Leu Gly Gly Tyr Ala Lys Met Ala Gin Gly 100 105 110
Phe Leu Lys 115
INFORMATION FOR SEQ ID NO:238:
(ϋi SEQUENCE CHARACTERISTICS:
(A) LENGTH: 69 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii! 1 MOLECULE TYPE: peptide
(ix! 1 FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..69
( (DD)) OOTTHHEERR I INNFFOORRMMAATTIIOONN:: // C( :eerreess SSeeqq.. IIDD 11444477558800 ( (xxii)! ! SSEEQQUUEENNCCEE DDEESSCCRRIIPPTTIIOONN:: SSEEQQ I: IDD NNOO:: 223388::
Met Lys Arg Val Ala Leu Val Ser Thr Ser Thr Arg Leu A.rg Ser He
1 5 10 15 S Seerr T Thhrr T Thhrr TThhrr S Seerr A Arrgg H Hiiss TThhrr PPrroo P Prroo VVaall LLeeuu V Vaall V Vaall L Leeuu Leu 20 25 30
Leu Arg Arg Val Arg Leu Ser Gin Gin Val Ser Leu Ser Arg Arg Leu 35 40 45
Arg Lys Thr Met Lys Ser Leu Val Val Gly Leu Glu Val Met Pro Arg 50 55 60
Trp Leu Lys Val Ser
65
(2) INFORMATION FOR SEQ ID NO:239:
(ϋ I SEQUENCE CHARACTERISTICS: (A) LENGTH: 717 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..717
(D) OTHER INFORMATION: / Ceres Seq. ID 1447922 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 239: cttcgtctct gtctccaaaa tcgaatcaaa atctctaaag tttcaatttt tttgttctgt 60 tctttttttt tttttaaaga atggcttcaa tttctgcaac tttgccttcg ccattgttac 120 tcacacagag aaaatccaat ctcacatcga ttcaaaaact cccattttct ctaactcgag 180 gtacgaatga tctttctcca ttatctctta ctcgaaaccc tagcagcatc agtctgatgg 240 tgaaagctag tggagaaagc tcagattcat cgactgatct cgacgttgtt agtacgattc 300 agaatgtttg ggataagtct gaagataggt taggtcttat tggtttgggt tttgctggta 360 ttgtagctct ttgggcatca ttgaatctca tcacggcaat tgacaaattg cccgttatct 420 cgagcggatt cgaactagtt ggtatcttgt tctccacgtg gttcacatat cgatatctct 480 tgttcaaacc ggacagacag gagctttcga aaattgtcaa gaaatcagta gcggacatac 540 ttggccagtg aaccttgtgt gtgtgataat acttcatctt tggaagatga tttgtttgca 600 agtttgtaaa attacatgac agggtggttg ttgtttctag tccaataatg tcatgcattt 660 gaaacctgta aatactttat tgttggtttt tggttgtgag caaaatcaat cttttct
(2) INFORMATION FOR SEQ ID NO:240: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 156 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: pept :ide
(ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..156
(D) OTHER INFORMATION: : / Ceres > Seq. ID 1447923
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:24C ):
Met Ala Ser He Ser Ala Thr Leu Pro Ser Pro Leu Leu Leu Thr Gin
1 5 10 15
Arg Lys Ser Asn Leu Thr Ser He Gin Lys Leu Pro Phe Ser Leu Thr 20 25 30
Arg Gly Thr Asn Asp Leu Ser Pro Leu Ser Leu Thr Arg Asn Pro Ser 35 40 45
Ser He Ser Leu Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser 50 55 60
Thr Asp Leu Asp Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser
65 70 75 80
Glu Asp Arg Leu Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala 85 90 95
Leu Trp Ala Ser Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val 100 105 110
He Ser Ser Gly Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe 115 120 125
Thr Tyr Arg Tyr Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys 130 135 140
He Val Lys Lys Ser Val Ala Asp He Leu Gly Gin
145 150 155
(2) INFORMATION FOR SEQ ID NO:241:
(ϋi SEQUENCE CHARACTERISTICS:
(A) LENGTH: 104 amino acit is
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(HI I MOLECULE TYPE: peptide
(ix! 1 FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..: L04
(D) OTHER INFORMATION : / ( :eres Seq. ID 1447924
(xi; ) SEQUENCE DESCRIPTION: _ 3EQ : ID NO: 241:
Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser Thr Asp Leu Asp
1 5 10 15
Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser Glu Asp Arg Leu 20 25 30
Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala Leu Trp Ala Ser 35 40 45
Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val He Ser Ser Gly 50 55 60
Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe Thr Tyr Arg Tyr 65 70 75 80
Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys He Val Lys Lys
85 90 95
Ser Val Ala Asp He Leu Gly Gin 100
(2) INFORMATION FOR SEQ ID NO: 242: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 656 base pairs B ) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
V ) NAME/KEY: - ,B) LOCATION: 1..656 vD) OTHER INFORMATION: / Ceres Seq. ID 1448012 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:242: ggaatttctc actctctcta tctctcttag ccagctctga ccatttcgat ttttttccgg 60 tgaaaaggga gcagaaacat ggttgtacgt atcagattat cgagatttgg atgcaaaaat 120 cggccatttt ttagggttat ggctgctgat agcagatctc caagagacgg gaagcatctt 180 gaggtcttaσ gttacttcaa tcctttgcca ggccaggacg gtggtaagag gatgggtctc 240 aagttcgatc gaattaagta ctggttatct gttggtgctc agccatcaga cccggttcaa 300 cgccttcttt tcagatccgg tttacttcct cctccrccaa tggtggctat gggacgtaaa 360 ggtggagcac gagacacacg cccagttgat ccaatgactg gtcgctatgt ggatgcagag 420 aataaaacag ttaatgccaa tgataaccag ccraaggaag aggattcaga agacaagatt 480 gcatgattca ttagccttct gtcgtcgtag cttttcaagt tcactttgtt gtcgattata 540 ttgtgtaatg cagcattaga caaccgactt gtttcctttg tttggcgata aacggcaagg 600 tgtttggcac tttttgcaga aacggcacat attttgcatt gggatatttt aatttt (2) INFORMATION FOR SEQ ID NO:243: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 135 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE: A) NAME/KEY: peptide (B) LOCATION: 1..135 vD) OTHER INFORMATION: / Ceres Seq. ID 1448013 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:243:
Met Val Val Arg He Arg Leu Ser Arg Phe Gly Cys Lys Asn Arg Pro 1 5 10 15
Phe Phe Arg Val Met Ala Ala Asp Ser Arg Ser Pro Arg Asp Gly Lys 20 25 30 His Leu Glu Val Leu Gly Tyr Phe Asn Pro Leu Pro Gly Gin Asp Gly 35 40 45
Gly Lys Arg Met Gly Leu Lys Phe Asp Arg He Lys Tyr Trp Leu Ser
50 55 60
Val Gly Ala Gin Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser 65 70 75 80
Gly Leu Leu Pro Pro Pro Pro Met Val Ala Met Gly Arg Lys Gly Gly
85 90 95
Ala Arg Asp Thr Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp 100 105 110 Ala Glu Asn Lys Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu 115 120 125
Asp Ser Glu Asp Lys He Ala 130 135
(2) INFORMATION FOR SEQ ID NO: 244: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 ammo acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: / Ceres Seq. ID 1448014 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 244: Met Ala Ala Asp Ser Arg Ser Pro Arg Asp Gly Lys His Leu Glu Val 1 5 10 15
Leu Gly Tyr Phe Asn Pro Leu Pro Gly Gin Asp Gly Gly Lys Arg Met
20 25 30
Gly Leu Lys Phe Asp Arg He Lys Tyr Trp Leu Ser Val Gly Ala Gin 35 40 45 Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser Gly Leu Leu Pro 50 55 60
Pro Pro Pro Met Val Ala Met Gly Arg Lys Gly Gly Ala Arg Asp Thr 65 70 75 80
Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp Ala Glu Asn Lys 85 " 90 95
Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu Asp Ser Glu Asp
100 105 110
Lys He Ala 115 (2) INFORMATION FOR SEQ ID NO: 245: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 84 ammo acids
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..84 (D) OTHER INFORMATION: / Ceres Seq. ID 1448015
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:245: Met Gly Leu Lys Phe Asp Arg He Lys Tyr Trp Leu Ser Val Gly Ala 1 5 10 15
Gin Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser Gly Leu Leu 20 25 30
Pro Pro Pro Pro Met Val Ala Met Gly Arg Lys Gly Gly Ala Arg Asp
35 40 45
Thr Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp Ala Glu Asn 50 55 60 Lys Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu Asp Ser Glu 65 70 75 " 80
Asp Lys He Ala
(2) INFORMATION FOR SEQ ID NO:246: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 458 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (11) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..458
(D) OTHER INFORMATION: / Ceres Seq. ID 1448135 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:246: aattttctag ggttttgaag agtgtctctc gtcgccgttg taattcctct gttagcaaat 60 cgacaaaatg ggtcactcta atgtatggaa ctctcatccg aagaagtacg gtcctggatc 120 tcgtttatgc cgtgtgtgcg ggaactcgca cgggctgatc cggaagtatg gtttgaactg 180 ctgcagacag tgtttccgta gcaacgctaa ggagattgga ttcattaagt accgttaatc 240 aagcaccaac ttcatgattg atgcttaatg atataaacat gaaggcgtcg atgggtttgg 300 cttttaagct tttgtagttt ttgaaatttt tacttttgag aaccattgtt attttgggag 360 ttaattaagt tgttgaacct ctcattaagc atgtcttatt ttggattaat gatgttttgg 420 ctattctcgy atttttgttt tatcagtcaa atttgact
(2) INFORMATION FOR SEQ ID NO:247:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 51 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..51
(D) OTHER INFORMATION: / Ceres Seq. ID 1448136
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 247:
Phe Ser Arg Val Leu Lys Ser Val Ser Arg Arg Arg Cys Asn Ser Ser
1 5 10 15
Val Ser Lys Ser Thr Lys Trp Val Thr Leu Met Tyr Gly Thr Leu He
20 30 Arg Arg Ser Th Val Leu Asp Leu Val Tyr Ala Val Cys Ala Gly Thr
35 40 45
Arg Thr Gly 50
(2) INFORMATION FOR SEQ ID NO: 248:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 56 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..56
(D) OTHER INFORMATION: / Ceres Seq. ID 1448137
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:248:
Met Gly His Ser Asn Val Trp Asn Ser His Pro Lys Lys Tyr Gly Pro
1 5 10 15
Gly Ser Arg Leu Cys Arg Val Cys Gly Asn Ser His Gly Leu He Arg
20 25 30
Lys Tyr Gly Leu Asn Cys Cys Arg Gin Cys Phe Arg Ser Asn Ala Lys
35 40 45
Glu He Gly Phe He Lys Tyr Arg 50 55
(2) INFORMATION FOR SEQ ID NO: 249:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 38 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..38 (D) OTHER INFORMATION: / Ceres Seq. ID 1448138
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 249: Met Glu Leu Ser Ser Glu Glu Val Arg Ser Trp He Ser Phe Met Pro 1 5 10 15
Cys Val Arg Glu Leu Ala Arg Ala Asp Pro Glu Val Trp Phe Glu Leu 20 25 30 Leu Gin Thr Val Phe Pro
35 (2) INFORMATION FOR SEQ ID NO:250: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 603 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..603
(D) OTHER INFORMATION: / Ceres Seq. ID 1448185 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:250: gaagaagaga gtatcgttgt gaggtttggg gatcgcgaaa atggaggrtc caggttcatc 60 gaagaagatg atcgcaacgc aagaagagat gtctgcagct aaaatagcac ttggatctag 120 agatatgtgc gctcatctct tgattccgct caacaaatgt cgtcaggctg agttttacct 180 tccatggaaa tgtgaagacg agcgtcacgt ttatgagaag tgtgaatacg agcttgttat 240 ggagagaatg cttgcgatga agaagatccg tgaagaagaa gctttggcta aacagaataa 300 actacaagga aacgctgctg ttcctcttat ccctaaaact gctaatgctt aggattcgat 360 tccttctcca atttgccgat tccagattcc gggattctct ggaactgtga agatggtggg 420 ggctctgctt ttcaatcttt ttcttcttgc tagtgatgaa aaattgttgc tacattttca 480 gatgtgaatg ttcaagattc tctatctttt tttttttttt gaactctttt taacttggag 540 tggtttccca aaaaataaga tgcaaaactc atctttttgt tggttttcta tctttaatct 600 gtg
(2) INFORMATION FOR SEQ ID NO:251: ( ) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 103 amino acids (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..103
(D) OTHER INFORMATION: / Ceres Seq. ID 1448186 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 251: Met Glu Val Pro Gly Ser Ser Lys Lys Met He Ala Thr Gin Glu Glu 1 5 10 15 Met Ser Ala Ala Lys He Ala Leu Gly Ser Arg Asp Met Cys Ala His
20 25 30
Leu Leu He Pro Leu Asn Lys Cys Arg Gin Ala Glu Phe Tyr Leu Pro
35 40 45
Trp Lys Cys Glu Asp Glu Arg His Val Tyr Glu Lys Cys Glu Tyr Glu 50 55 60
Leu Val Met Glu Arg Met Leu Ala Met Lys Lys He Arg Glu Glu Glu 65 70 75 80
Ala Leu Ala Lys Gin Asn Lys Leu Gin Gly Asn Ala Ala Val Pro Leu 85 90 95 He Pro Lys Thr Ala Asn Ala
100 (2) INFORMATION FOR SEQ ID NO: 252: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 94 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..94
(D) OTHER INFORMATION: / Ceres Seq. ID 1448187 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 252: Met He Ala Thr Gin Glu Glu Met Ser Ala Ala Lys He Ala Leu Gly 1 5 10 15
Ser Arg Asp Met Cys Ala His Leu Leu He Pro Leu Asn Lys Cys Arg 20 25 30
Gin Ala Glu Phe Tyr Leu Pro Trp Lys Cys Glu Asp Glu Arg His Val
35 40 45
Tyr Glu Lys Cys Glu Tyr Glu Leu Val Met Glu Arg Met Leu Ala Met 50 55 60 Lys Lys He Arg Glu Glu Glu Ala Leu Ala Lys Gin Asn Lys Leu Gin 65 70 75 80
Gly Asn Ala Ala Val Pro Leu He Pro Lys Thr Ala Asn Ala
85 90
(2) INFORMATION FOR SEQ ID NO: 253: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 87 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..87
(D) OTHER INFORMATION: / Ceres Seq. ID 1448188 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:253~:
Met Ser Ala Ala Lys He Ala Leu Gly Ser Arg Asp Met Cys Ala His 1 5 10 15
Leu Leu He Pro Leu Asn Lys Cys Arg Gin Ala Glu Phe Tyr Leu Pro 20 25 30 Trp Lys Cys Glu Asp Glu Arg His Val Tyr Glu Lys Cys Glu Tyr Glu 35 40 45
Leu Val Met Glu Arg Met Leu Ala Met lys Lys He Arg Glu Glu Glu
50 55 60
Ala Leu Ala Lys Gin Asn Lys Leu Gin Gly Asn Ala Ala Val Pro Leu 65 70 75 80
He Pro Lys Thr Ala Asn Ala
85 (2) INFORMATION FOR SEQ ID NO: 254: U) SEQUENCE CHARACTERISTICS: (A) LENGTH: 2034 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..2034
(D) OTHER INFORMATION: / Ceres Seq. ID 1450875 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:254: tttatcaaaa tcgatggctg cttctagatt gtgttccgcg gcggcgatag ctgctgcctt 60 cacttcaatg tcaatgtctc agaaccgtgc ttacgccgat tcttctcgat tccggtttcc 120 tttcttttct tcttctcctt ctcctcctcc gtcagattct ccggcgaatc aatcttctac 180 aaactctagt aagtctaaag cagagcctga tgagcctaaa ggatcgggtt ttgatcctga 240 ggctcttgag agagctgcta aagctcttag agatatcaat agctctcccc attccaaaca 300 ggtgtttgat ctcatgagga agcaggagaa aactcggtta gctgaattag cggcagagac 360 ttctcattac gaagctattc aagcacacaa tgatattggc agacagcaga aattggctga 420 ggaccagaga aatcttttgc agacacaggc gcaaaccaaa gcgcaaaatc tgcgatatga 480 ggatgaattg gccagaaaga gacagcagac agatcatgaa gctcagaggc atcataatgt 540 ggaattggtt aagatgcaag aggcgtcttc tatcaggaaa gagaaggcaa aaatcgccac 600 agaagaacag atccaagctc agcatcgcca aactgagaaa gagagagctg aacttgagcg 660 agagacgatt cgtgtcaagg ccatggctga agctgaaggt cgggctcatg aagccaaact 720 tactgaagag caaaacagaa gattgcttat ggaaaggatt aatggtgaaa gagagaagtg 780 gcttgctgca atcaacacaa tgttcagtca catcgaaggg ggattcagga ccttattaac 840 tgatcgaaat aagctgatta tgactgttgg aggagctact gcattagctg caggggttta 900 tacaactcgt gaaggagcta gagttacatg gggttatatt aataggatgc ttggacaacc 960 gtcacttatt cgagaatctt ccatgcgtag atttccatgg acaggctcag tgtctcaatt 1020 taagaacagg atctcagggg ctgcagcagc ttctgcagca gaaggcaaaa agccgcttga 1080 taatgtaatt ctccatactt ctttgaagaa acgaatcgag cgtctcgcta gagctacagc 1140 aaacaccaaa tcccatcaag caccattccg caacatgatg ttttatggac ctcctggtac 1200 cggtaaaact atggtggcaa gggaaatagc tcggaaatcg ggtctggatt atgctatgat 1260 gacaggaggt gatgttgctc ccttgggatc acaagctgtt actaaaatcc atcagatatt 1320 tgattgggct aagaaatcga acagaggctt actccttttc attgatgaag ccgatgcttt 1380 tctatgcgag cgtaacagca cttacatgag tgaggctcaa cgtagtgctc tgaacgcttt 1440 gctcttccga actggtgatc aatctcggga cattgttctt gtcttggcta caaacagacc 1500 tggagatctc gatagtgcgg ttacagacag gattgatgaa gtcattgagt tcccacttcc 1560 aggggaagaa gaacgtttca agcttctcaa tctctatctc aacaaatatc taaagatggg 1620 tgataacaac gaagacacaa aaccgaaatg gagtcatttg tttaagaagc tgtcacagaa 1680 gattaccgtt gaagaagact taactgataa agtgatttct gaggctgcaa agaagacaga 1740 aggattctct ggccgtgaga ttgcaaagct tgtggctgga gtacaagctg gagtgtacgg 1800 acgagcggat tgtgttttgg attcacagct ttttaaagag attgttgaat ataaggttga 1860 agaacatcac cgaaggcata tgcttgcttc tgaaggtttt cagccattac tcttctctta 1920 gtcatttgga ttttgattat acatgtcatt tacttgatca gaaagaagaa tctgattgtt 1980 ttaaaatgag tcctaaaatt gaatttttag attaaacatg ttaaagagtt ttac
\ , INFORMAT ION FOR SEQ I D NO : 2 _ ) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 639 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..639
(D) OTHER INFORMATION: / Ceres Seq. ID 1450876 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:255: Leu Ser Lys Ser Met Ala Ala Ser Arg Leu Cys Ser Ala Ala Ala He 1 5 10 15
Ala Ala Ala Phe Thr Ser Met Ser Met Ser Gin Asn Arg Ala Tyr Ala
20 25 30
Asp Ser Ser Arg Phe Arg Phe Pro Phe Phe Ser Ser Ser Pro Ser Pro
35 " 40 45
Pro Pro Ser Asp Ser Pro Ala Asn Gin Ser Ser Thr Asn Ser Ser Lys
50 55 60
Ser Lys Ala Glu Pro Asp Glu Pro Lys Gly Ser Gly Phe Asp Pro Glu 65 70 75 80
Ala Leu Glu Arg Ala Ala Lys Ala Leu Arg Asp He Asn Ser Ser Pro
85 90 95
His Ser Lys Gin Val Phe Asp Leu Met Arg Lys Gin Glu Lys Thr Arg
100 105 110
Leu Ala Glu Leu Ala Ala Glu Thr Ser His Tyr Glu Ala He Gin Ala
115 120 125
His Asn Asp He Gly Arg Gin Gin Lys Leu Ala Glu Asp Gin Arg Asn
130 135 140
Leu Leu Gin Thr Gin Ala Gin Thr Lys Ala Gin Asn Leu Arg Tyr Glu 145 150 155 160
Asp Glu Leu Ala Arg Lys Arg Gin Gin Thr Asp His Glu Ala Gin Arg
165 170 175
His His Asn Val Glu Leu Val Lys Met Gin Glu Ala Ser Ser He Arg
180 185 190
Lys Glu Lys Ala Lys He Ala Thr Glu Glu Gin He Gin Ala Gin His
195 200 205
Arg Gin Thr Glu Lys Glu Arg Ala Glu Leu Glu Arg Glu Thr He Arg
210 215 220
Val Lys Ala Met Ala Glu Ala Glu Gly Arg Ala His Glu Ala Lys Leu 225 230 235 240
Thr Glu Glu Gin Asn Arg Arg Leu Leu Met Glu Arg He Asn Gly Glu
245 250 255
Arg Glu Lys Trp Leu Ala Ala He Asn Thr Met Phe Ser His He Glu 260 265 270
Gly Gly Phe Arg Thr Leu Leu Thr Asp Arg Asn Lys Leu He Met Thr
275 280 285
Val Gly Gly Ala Thr Ala Leu Ala Ala Gly Val Tyr Thr Thr Arg Glu
290 295 300 Gly Ala Arg Val Thr Trp Gly Tyr He Asn Arg Met Leu Gly Gin Pro
305 310 315 320
Ser Leu He Arg Glu Ser Ser Met Arg Arg Phe Pro Trp Thr Gly Ser
325 330 335
Val Ser Gin Phe Lys Asn Arg He Ser Gly Ala Ala Ala Ala Ser Ala 340 345 350
Ala Glu Gly Lys Lys Pro Leu Asp Asn Val He Leu His Thr Ser Leu
355 360 365
Lys Lys Arg He Glu Arg Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser
370 375 380 His Gin Ala Pro Phe Arg Asn Met Met Phe Tyr Gly Pro Pro Gly Thr
385 390 395 400
Gly Lys Thr Met Val Ala Arg Glu He Ala Arg Lys Ser Gly Leu Asp
405 410 415
Tyr Ala Met Met Thr Gly Gly Asp Val Ala Pro Leu Gly Ser Gin Ala 420 425 430
Val Thr Lys He His Gin He Phe Asp Trp Ala Lys Lys Ser Asn Arg
435 440 445
Gly Leu Leu Leu Phe He Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg
450 455 460 Asn Ser Thr Tyr Met Ser Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu
465 470 475 480
Leu Phe Arg Thr Gly Asp Gin Ser Arg P sp He Val Leu Val Leu Ala
485 490 495
Thr Asn Arg Pro Gly Asp Leu Asp Ser Ala Val Thr Asp Arg He Asp 500 505 510
Glu Val He Glu Phe Pro Leu Pro Gly Glu Glu Glu Arg Phe Lys Leu
515 520 525
Leu Asn Leu Tyr Leu Asn Lys Tyr Leu Lys Met Gly Asp Asn Asn Glu
530 535 540 Asp Thr Lys Pro Lys Trp Ser His Leu Phe Lys Lys Leu Ser Gin Lys
545 550 555 560
He Thr Val Glu Glu Asp Leu Thr Asp Lys Val He Ser Glu Ala Ala
565 570 575
Lys Lys Thr Glu Gly Phe Ser Gly Arg Glu He Ala Lys Leu Val Ala 580 585 590
Gly Val Gin Ala Gly Val Tyr Gly Arg Ala Asp Cys Val Leu Asp Ser
595 600 605
Gin Leu Phe Lys Glu He Val Glu Tyr Lys Val Glu Glu His His Arg 610 615 620 Arg His Met Leu Ala Ser Glu Gly Phe Gin Pro Leu Leu Phe Ser 625 630 635
(2) INFORMATION FOR SEQ ID NO:256: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 635 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..635
(D) OTHER INFORMATION: / Ceres Seq. ID 1450877 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 256: Met Ala Ala Ser Arg Leu Cys Ser Ala Ala Ala He Ala Ala Ala Phe 1 5 10 15
Thr Ser Met Ser Met Ser Gin Asn Arg Ala Tyr Ala Asp Ser Ser Arg 20 25 30
Phe Arg Phe Pro Phe Phe Ser Ser Ser Pro Ser Pro Pro Pro Ser Asp
35 40 45
Ser Pro Ala Asn Gin Ser Ser Thr Asn Ser Ser Lys Ser Lys Ala Glu 50 55 60 Pro Asp Glu Pro Lys Gly Ser Gly Phe Asp Pro Glu Ala Leu Glu Arg 65 70 75 80
Ala Ala Lys Ala Leu Arg Asp He Asn Ser Ser Pro His Ser Lys Gin
85 90 95
Val Phe Asp Leu Met Arg Lys Gin Glu Lys Thr Arg Leu Ala Glu Leu 100 105 110
Ala Ala Glu Thr Ser His Tyr Glu Ala He Gin Ala His Asn Asp He
115 120 125
Gly Arg Gin Gin Lys Leu Ala Glu .Asp Gin Arg Asn Leu Leu Gin Thr
130 135 140 Gin Ala Gin Thr Lys Ala Gin Asn Leu Arg Tyr Glu Asp Glu Leu Ala
145 150 155 160
Arg Lys Arg Gin Gin Thr Asp His Glu Ala Gin Arg His His Asn Val
165 170 175
Glu Leu Val Lys Met Gin Glu Ala Ser Ser He Arg Lys Glu Lys Ala 180 185 190
Lys He Ala Thr Glu Glu Gin He Gin Ala Gin His Arg Gin Thr Glu
195 200 205
Lys Glu Arg Ala Glu Leu Glu Arg Glu Thr He Arg Val Lys Ala Met
210 215 220 Ala Glu Ala Glu Gly Arg Ala His Glu Ala Lys Leu Thr Glu Glu Gin
225 230 235 240
Asn Arg Arg Leu Leu Met Glu Arg He Asn Gly Glu Arg Glu Lys Trp
245 250 255
Leu Ala Ala He Asn Thr Met Phe Ser His He Glu Gly Gly Phe Arg 260 265 270
Thr Leu Leu Thr Asp Arg Asn Lys Leu He Met Thr Val Gly Gly Ala
275 280 285
Thr Ala Leu Ala Ala Gly Val Tyr Thr Thr Arg Glu Gly Ala Arg Val
290 295 300 Thr Trp Gly Tyr He Asn Arg Met Leu Gly Gin Pro Ser Leu He Arg
305 310 315 320
Glu Ser Ser Met Arg Arg Phe Pro Trp Thr Gly Ser Val Ser Gin Phe
325 330 335
Lys Asn Arg He Ser Gly Ala Ala Ala Ala Ser Ala Ala Glu Gly Lys 340 345 350
Lys Pro Leu Asp Asn Val He Leu His Thr Ser Leu Lys Lys Arg He
355 360 365
Glu Arg Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser His Gin Ala Pro
370 375 380 Phe Arg Asn Met Met Phe Tyr Gly Pro Pro Gly Thr Gly Lys Thr Met
385 390 395 400
Val Ala Arg Glu He Ala Arg Lys Ser Gly Leu Asp Tyr Ala Met Met
405 410 415
Thr Gly Gly Asp Val Ala Pro Leu Gly Ser Gin Ala Val Thr Lys He 420 425 430
His Gin He Phe Asp Trp Ala Lys Lys Ser Asn Arg Gly Leu Leu Leu
435 440 445
Phe He Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg Asn Ser Thr Tyr
450 455 460 Met Ser Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu Leu Phe Arg Thr
465 470 475 480
Gly Asp Gin Ser Arg Asp He Val Leu Val Leu Ala Thr Asn Arg Pro 485 490 495
Gly Asp Leu Asp Ser Ala Val Thr Asp Arg He Asp Glu Val He Glu
500 505 510
Phe Pro Leu Pro Gly Glu Glu Glu Arg Phe Lys Leu Leu Asn Leu Tyr 515 520 525
Leu Asn Lys Tyr Leu Lys Met Gly Asp Asn Asn Glu Asp Thr Lys Pro
530 535 540
Lys Trp Ser His Leu Phe Lys Lys Leu Ser Gin Lys He Thr Val Glu 545 550 555 560 Glu Asp Leu Thr Asp Lys Val He Ser Glu Ala Ala Lys Lys Thr Glu
565 570 575
Gly Phe Ser Gly Arg Glu He Ala Lys Leu Val Ala Gly Val Gin Ala
580 585 590
Gly Val Tyr Gly Arg Ala Asp Cys Val Leu Asp Ser Gin Leu Phe Lys 595 600 605
Glu He Val Glu Tyr Lys Val Glu Glu His His Arg Arg His Met Leu
610 615 620
Ala Ser Glu Gly Phe Gin Pro Leu Leu Phe Ser 625 630 635 (2) INFORMATION FOR SEQ ID NO: 257: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 617 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..617 (D) OTHER INFORMATION: / Ceres Seq. ID 1450878
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 257: Met Ser Met Ser Gin Asn Arg Ala Tyr Ala Asp Ser Ser Arg Phe Arg 1 5 10 15
Phe Pro Phe Phe Ser Ser Ser Pro Ser Pro Pro Pro Ser Asp Ser Pro 20 25 30
Ala Asn Gin Ser Ser Thr Asn Ser Ser Lys Ser Lys Ala Glu Pro Asp
35 40 45
Glu Pro Lys Gly Ser Gly Phe Asp Pro Glu Ala Leu Glu Arg Ala Ala 50 55 60 Lys Ala Leu Arg Asp He Asn Ser Ser Pro His Ser Lys Gin Val Phe 65 70 75 80
Asp Leu Met Arg Lys Gin Glu Lys Thr Arg Leu Ala Glu Leu Ala Ala
85 90 95
Glu Thr Ser His Tyr Glu Ala He Gin Ala His Asn Asp He Gly Arg 100 105 110
Gin Gin Lys Leu Ala Glu Asp Gin Arg Asn Leu Leu Gin Thr Gin Ala
115 120 125
Gin Thr Lys Ala Gin Asn Leu Arg Tyr Glu Asp Glu Leu Ala Arg Lys
130 135 140 Arg Gin Gin Thr Asp His Glu Ala Gin Arg His His Asn Val Glu Leu
145 150 155 160
Val Lys Met Gin Glu Ala Ser Ser He Arg Lys Glu Lys Ala Lys He
165 170 175
Ala Thr Glu Glu Gin He Gin Ala Gin His Arg Gin Thr Glu Lys Glu 180 185 190
Arg Ala Glu Leu Glu Arg Glu Thr He Arg Val Lys Ala Met Ala Glu
195 200 205
Ala Glu Gly Arg Ala His Glu Ala Lys Leu Thr Glu Glu Gin Asn Arg
210 215 220 Arg Leu Leu Met Glu Arg He Asn Gly Glu Arg Glu Lys Trp Leu Ala
225 230 235 240
Ala He Asn Thr Met Phe Ser His He Glu Gly Gly Phe Arg Thr Leu 245 250 255
Leu Thr Asp Arg Asn Lys Leu He Met Thr Val Gly Gly Ala Thr Ala
260 265 270
Leu Ala Ala Gly Val Tyr Thr Thr Arg Glu Gly Ala Arg Val Thr Trp 275 280 285
Gly Tyr He Asn Arg Met Leu Gly Gin Pro Ser Leu He Arg Glu Ser
290 295 300
Ser Met Arg Arg Phe Pro Trp Thr Gly Ser Val Ser Gin Phe Lys Asn 305 310 315 320 Arg He Ser Gly Ala Ala Ala Ala Ser Ala Ala Glu Gly Lys Lys Pro
325 330 335
Leu Asp Asn Val He Leu His Thr Ser Leu Lys Lys Arg He Glu Arg
340 345 350
Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser His Gin Ala Pro Phe Arg 355 360 365
Asn Met Met Phe Tyr Gly Pro Pro Gly Thr Gly Lys Thr Met Val Ala
370 375 380
Arg Glu He Ala Arg Lys Ser Gly Leu Asp Tyr Ala Met Met Thr Gly 385 390 395 400 Gly Asp Val Ala Pro Leu Gly Ser Gin Ala Val Thr Lys He His Gin
405 410 415
He Phe A.sp Trp Ala Lys Lys Ser Asn Arg Gly Leu Leu Leu Phe He
420 425 430
Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg Asn Ser Thr Tyr Met Ser 435 440 445
Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu Leu Phe Arg Thr Gly Asp
450 455 460
Gin Ser Arg Asp He Val Leu Val Leu Ala Thr Asn Arg Pro Gly Asp 465 470 475 480 Leu Asp Ser Ala Val Thr Asp Arg He Asp Glu Val He Glu Phe Pro
485 490 495
Leu Pro Gly Glu Glu Glu Arg Phe Lys Leu Leu Asn Leu Tyr Leu Asn
500 505 510
Lys Tyr Leu Lys Met Gly Asp Asn Asn Glu Asp Thr Lys Pro Lys Trp 515 520 525
Ser His Leu Phe Lys Lys Leu Ser Gin Lys He Thr Val Glu Glu Asp
530 535 540
Leu Thr Asp Lys Val He Ser Glu Ala Ala Lys Lys Thr Glu Gly Phe 545 550 555 560 Ser Gly Arg Glu He Ala Lys Leu Val Ala Gly Val Gin Ala Gly Val
565 570 575
Tyr Gly Arg Ala Asp Cys Val Leu Asp Ser Gin Leu Phe Lys Glu He
580 585 590
Val Glu Tyr Lys Val Glu Glu His His Arg Arg His Met Leu Ala Ser 595 600 605
Glu Gly Phe Gin Pro Leu Leu Phe Ser
610 615
(2) INFORMATION FOR SEQ ID NO: 258: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 478 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..478
(D) OTHER INFORMATION: / Ceres Seq. ID 1459191 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 258: aaccctcttg gaaagagtct caacacttgc agagaaaaag aacaaggaag atcccggaaa 60 atggcaacgg cgattgtacg ttcagctctt tcccgagcag tgactcgcgc agtccgaaga 120 catccgtcgc tcctaagcga aacttttcct cttccgccgg ccatgacgat gcttatgaag 180 ctgcgaagtg ggagaagata acttatctgg gtattgctag ttgcactgct ctagctgtct 240 atgttttatc caagggccat catcacggcg aagacaagga gtttccttgg ggtccggatg 300 gtctgtttga ggtgaagcac aacaaagagc actgagtctt gcgtggtcat aataacgtct 360 tctaggttta tttgaaaggc taaaatgttt taccgtattt gttctcaccg tttgtcaacg 420 atttgctact ccaatctctt ttcttttgtt gggaaataaa agttaatact ttgcttgg (2) INFORMATION FOR SEQ ID NO: 259: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 66 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..66
(D) OTHER INFORMATION: / Ceres Seq. ID 1459192 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:259: Asn Pro Leu Gly Lys Ser Leu Asn Thr Cys Arg Glu Lys Glu Gin Gly 1 5 10 15 Arg Ser Arg Lys Met Ala Thr Ala He Val Arg Ser Ala Leu Ser Arg
20 25 30
Ala Val Thr Arg Ala Val Arg Arg His Pro Ser Leu Leu Ser Glu Thr
35 40 45
Phe Pro Leu Pro Pro Ala Met Thr Met Leu Met Lys Leu Arg Ser Gly 50 55 60
Arg Arg 65
(2) INFORMATION FOR SEQ ID NO: 260: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 110 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..110
(D) OTHER INFORMATION: / Ceres Seq. ID 1459193 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 260: Pro Ser Trp Lys Glu Ser Gin His Leu Gin Arg Lys Arg Thr Arg Lys 1 5 10 15
He Pro Glu Asn Gly Asn Gly Asp Cys Thr Phe Ser Ser Phe Pro Ser
20 25 30
Ser Asp Ser Arg Ser Pro Lys Thr Ser Val Ala Pro Lys Arg Asn Phe 35 40 45
Ser Ser Ser Ala Gly His Asp Asp Ala Tyr Glu Ala Ala Lys Trp Glu
50 55 60
Lys He Thr Tyr Leu Gly He Ala Ser Cys Thr Ala Leu Ala Val Tyr 65 70 75 80 Val Leu Ser Lys Gly His His His Gly Glu Asp Lys Glu Phe Pro Trp
85 90 95
Gly Pro Asp Gly Leu Phe Glu Val Lys His Asn Lys Glu His 100 105 110
(2) INFORMATION FOR SEQ ID NO: 261: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 741 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..741
(D) OTHER INFORMATION: / Ceres Seq. ID 1461848 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:261: attttagtac attgttgacc atctttttcg tatagactac tatctctgat ctcttgcgag 60 ttaagtcagt aactaggaaa attcagaagc gctctcaatc tcaaaaatat ccatggcggc 120 gattacagaa tttctaccaa aagagtacgg atatgtcgtt ctcgtcctcg tcttctactg 180 tttcctcaac ctctggatgg gtgctcaagt cggcagagct cgcaaaaggt acaacgtccc 240 gtatccaact ctatatgcaa tagaatcaga aaacaaagat gctaagctct tcaactgtgt 300 tcagagagga catcaaaact ctttagagat gatgccaatg tatttcatac tgatgatcct 360 cggtgggatg aagcaccctt gtatctgtac tggccttggt ttgctttaca acgttagccg 420 attcttctac tttaaaggtt atgctactgg agatcccatg aagcgtctta cgatcgggaa 480 atacggtttc ttggggttgc taggtctgat gatatgtacc atctcgtttg gtgtcactct 540 gatccttgct taagctactc gtttctgggg ttaatgattc tctggtttgc tcgaagaata 600 tagaaccaat gcttgtaagc tgtccacaaa acttgtgtaa tactttagag tttgtcactt 660 ttaaaagttt gtaataaatc atggcttcat agaacagttg aaatttcaca tccgtagacg 720 ttaataaaga tttgaattat g (2) INFORMATION FOR SEQ ID NO: 262:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 146 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..146 (D) OTHER INFORMATION: / Ceres Seq. ID 1461849
(xi! SEQUENCE DESCRIPTION: SEQ ID NO: 262: Met Ala Ala He Thr Glu Phe Leu Pro Lys Glu Tyr Gly Tyr Val Val 1 5 10 15
Leu Val Leu Val Phe Tyr Cys Phe Leu Asn Leu Trp Met Gly Ala Gin
20 25 30
Val Gly Arg Ala Arg Lys Arg Tyr Asn Val Pro Tyr Pro Thr Leu Tyr
35 40 45
Ala He Glu Ser Glu Asn Lys Asp Ala Lys Leu Phe Asn Cys Val Gin
50 55 60
Arg Gly His Gin Asn Ser Leu Glu Met Met Pro Met Tyr Phe He Leu
65 70 75 80
Met He Leu Gly Gly Met Lys His Pro Cys He Cys Thr Gly Leu Gly
90 95
Leu Leu Tyr Asn Val Ser Arg Phe Phe Tyr Phe Lys Gly Tyr Ala Thr
100 105 110
Gly Asp Pro Met Lys Arg Leu Thr He Gly Lys Tyr Gly Phe Leu Gly
115 120 125
Leu Leu Gly Leu Met He Cys Thr He Ser Phe Gly Val Thr Leu He
130 135 140
Leu Ala 145 (2) INFORMATION FOR SEQ ID NO: 263:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 118 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..118
(D) OTHER INFORMATION: / Ceres Seq. ID 1461850 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 263: Met Gly Ala Gin Val Gly Arg Ala Arg Lys Arg Tyr Asn Val Pro Tyr 1 5 10 15 Pro Thr Leu Tyr Ala He Glu Ser Glu Asn Lys Asp Ala Lys Leu Phe
20 25 30
Asn Cys Val Gin Arg Gly His Gin Asn Ser Leu Glu Met Met Pro Met
35 40 45
Tyr Phe He Leu Met He Leu Gly Gly Met Lys His Pro Cys He Cys
50 55 60
Thr Gly Leu Gly Leu Leu Tyr Asn Val Ser Arg Phe Phe Tyr Phe Lys 65 70 75 80
Gly Tyr Ala Thr Gly Asp Pro Met Lys Arg Leu Thr He Gly Lys Tyr
85 90 95 Gly Phe Leu Gly Leu Leu Gly Leu Met He Cys Thr He Ser Phe Gly 100 105 110
Val Thr Leu He Leu Ala 115
(2) INFORMATION FOR SEQ ID NO: 264:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 1461851 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 264: Met Met Pro Met Tyr Phe He Leu Met He Leu Gly Gly Met Lys His 1 5 10 15
Pro Cys He Cys Thr Gly Leu Gly Leu Leu Tyr Asn Val Ser Arg Phe
20 25 30
Phe Tyr Phe Lys Gly Tyr Ala Thr Gly Asp Pro Met Lys Arg Leu Thr
35 40 45
He Gly Lys Tyr Gly Phe Leu Gly Leu Leu Gly Leu Met He Cys Thr
50 55 60
He Ser Phe Gly Val Thr Leu He Leu Ala 65 70
(2) INFORMATION FOR SEQ ID NO: 265: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 469 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: DNA (genomic)
(ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..469 (D) OTHER INFORMATION: / Ceres Seq. ID 1472772
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 265: atatagaata taaccatatt ccggacatga agatcgtgac attggtactc gtcgtcttcg 60 tcatactttc gacatcattc ccggctgcca tcaaagccga agacacggga gatacaggaa 120 atgtgggagt gacatgtgac gcaaggcagc ttcagccttg ccttgccgcg attacgggag 180 gaggacaacc ctcgggtgca tgttgtgcaa agcttacaga gcaacagtca tgcctatgtg 240 gtttcgctaa gaaccctgcg ttcgcacagt acattagctc tccaaacgct cgcaaagtgc 300 tccttgcttg caatgttgct tatcccactt gttgaaactt atctagattt tataaataaa 360 taaacgaaag gaaataaatt acattatatc aaacgttatg atacaattca accgtttgtg 420 ttaatgtact ggcttacatg gttaaataaa gtttaatttc ttggttgcc (2) INFORMATION FOR SEQ ID NO: 266: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 110 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..110 (D) OTHER INFORMATION: / Ceres Seq. ID 1472773
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 266: He Glu Tyr Asn His He Pro Asp Met Lys He Val Thr Leu Val Leu 1 5 10 15
Val Val Phe Val He Leu Ser Thr Ser Phe Pro Ala Ala He Lys Ala 20 25 30
Glu Asp Thr Gly Asp Thr Gly Asn Val Gly Val Thr Cys Asp Ala Arg
35 40 45
Gin Leu Gin Pro Cys Leu Ala Ala He Thr Gly Gly Gly Gin Pro Ser 50 55 60 Gly Ala Cys Cys Ala Lys Leu Thr Glu Gin Gin Ser Cys Leu Cys Gly 65 70 75 80
Phe Ala Lys Asn Pro Ala Phe Ala Gin Tyr He Ser Ser Pro Asn Ala
85 90 95
Arg Lys Val Leu Leu Ala Cys Asn Val Ala Tyr Pro Thr Cys 100 105 110
(2) INFORMATION FOR SEQ ID NO: 267: !i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..102
(D) OTHER INFORMATION: / Ceres Seq. ID 1472774 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 267: Met Lys He Val Thr Leu Val Leu Val Val Phe Val He Leu Ser Thr 1 5 10 15 Ser Phe Pro Ala Ala He Lys Ala Glu Asp Thr Gly Asp Thr Gly Asn
20 25 30
Val Gly Val Thr Cys Asp Ala Arg Gin Leu Gin Pro Cys Leu Ala Ala
35 40 45
He Thr Gly Gly Gly Gin Pro Ser Gly Ala Cys Cys Ala Lys Leu Thr 50 55 60
Glu Gin Gin Ser Cys Leu Cys Gly Phe Ala Lys Asn Pro Ala Phe Ala 65 70 75 80
Gin Tyr He Ser Ser Pro Asn Ala Arg Lys Val Leu Leu Ala Cys Asn 85 90 95 Val Ala Tyr Pro Thr Cys
100 (2) INFORMATION FOR SEQ ID NO: 268: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1056 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..1056
(D) OTHER INFORMATION: / Ceres Seq. ID 1533352
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 268: aaaaaaaaaa accaaagcaa aaaaatggct ttgaaactca cttctccgcc ttcagttttc 60 tcacaatcaa ggagattatc ttcttcttcg ttaattccga taaggtcaaa atccacattc 120 accggatttc gatcgagaac cggtgtttat ttaagcaaaa cgacggcgct tcagtcgtct 180 acaaaactga gtgtggcggc ggagagtcct gcggcgacaa ttgcgacgga tgattggggg 240 aaagtatcgg cggttctgtt tgatatggac ggtgtgcttt gtaacagtga agatctttct 300 agacgcgccg ccgtggatgt ttttacggag atgggagttg aagtcactgt ggacgatttc 360 gttcctttta tgggaacagg tgaagccaag tttttaggag gtgttgcttc agtcaaagaa 420 gttaaaggat ttgatccaga tgcagctaaa aagagattct ttgaaatata tctcgataag 480 tatgcgaagc cagaatctgg gattggattt ccaggagcat tggagcttgt tactgagtgt 540 aagaacaaag gccttaaagt cgctgttgca tctagtgctg accgtatcaa agttgatgcg 600 aatctgaaag ctgctggttt gtctttgacc atgtttgatg ccattgtttc agcagatgcc 660 tttgagaatt tgaaaccagc tccagatatt ttcctggctg ctgcaaagat cttaggtgtg 720 cctaccagcg agtgtgttgt tattgaagat gcgcttgctg gagtccaagc cgcacaagct 780 gcgaacatga gatgtatagc cgtaaaaact actttatctg aagcaattct taaggatgct 840 ggtccttcaa tgatacgaga cgatattgga aacatctcaa tcaatgacat tctcactggt 900 ggctcagatt ctaccagtat gtagtctcaa agaaattcga tggaaaatat cgttcttttc 960 atgtgtattt tatttcttgt ttactccttt tgaaaacrtt tgaataaagg ggctttcttt 1020 gtaacgagat tacacattta aaacaatctt ttctgt (2) INFORMATION FOR SEQ ID NO:269: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 307 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE peptide •'ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..307
(D) OTHER INFORMATION: / Ceres Seq. ID 1533353
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:269:
Lys Lys Lys Asn Gin Ser Lys Lys Met Ala Leu Lys Leu Thr Ser Pro
10 15
Pro Ser Val Phe Ser Gin Ser Arg Arg Leu Ser Ser Ser Ser Leu He
20 25 30
Pro He Arg Ser Lys Ser Thr Phe Thr Gly Phe Arg Ser Arg Thr Gly 35 40 45
Val Tyr Leu Ser Lys Thr Thr Ala Leu Gin Ser Ser Thr Lys Leu Ser
50 55 60
Val Ala Ala Glu Ser Pro Ala Ala Thr He Ala Thr Asp Asp Trp Gly
65 70 75 80
Lys Val Ser Ala Val Leu Phe Asp Met Asp Gly Val Leu Cys Asn Ser 85 90 95
Glu Asp Leu Ser Arg Arg Ala Ala Val Asp Val Phe Thr Glu Met Gly 100 105 110
Val Glu Val Thr Val Asp Asp Phe Val Pro Phe Met Gly Thr Gly Glu 115 120 125
Ala Lys Phe Leu Gly Gly Val Ala Ser Val Lys Glu Val Lys Gly Phe 130 135 140
Asp Pro Asp Ala Ala Lys Lys Arg Phe Phe Glu He Tyr Leu Asp Lys
145 150 155 160
Tyr Ala Lys Pro Glu Ser Gly He Gly Phe Pro Gly Ala Leu Glu Leu 165 170 175
Val Thr Glu Cys Lys Asn Lys Gly Leu Lys Val Ala Val Ala Ser Ser 180 185 190
Ala Asp Arg He Lys Val Asp Ala Asn Leu Lys Ala Ala Gly Leu Ser 195 200 205
Leu Thr Met Phe Asp Ala He Val Ser Ala Asp Ala Phe Glu Asn Leu 210 215 220
Lys Pro Ala Pro Asp He Phe Leu Ala Ala Ala Lys He Leu Gly Val
225 230 235 240
Pro Thr Ser Glu Cys Val Val He Glu Asp Ala Leu Ala Gly Val Gin 245 250 255
Ala Ala Gin Ala Ala Asn Met Arg Cys He Ala Val Lys Thr Thr Leu 260 265 270
Ser Glu Ala He Leu Lys Asp Ala Gly Pro Ser Met He Arg Asp Asp 275 280 285 He Gly Asn He Ser He Asn Asp He Leu Thr Gly Gly Ser Asp Ser
290 295 300
Thr Ser Met 305 (2) INFORMATION FOR SEQ ID NC:270: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 299 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..299 (D) OTHER INFORMATION: / Ceres Seq. ID 1533354
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 270: Met Ala Leu Lys Leu Thr Ser Pro Pro Ser Val Phe Ser Gin Ser Arg 1 5 10 15
Arg Leu Ser Ser Ser Ser Leu He Pro He Arg Ser Lys Ser Thr Phe 20 25 30
Thr Gly Phe Arg Ser Arg Thr Gly Val Tyr Leu Ser Lys Thr Thr Ala
35 40 45
Leu Gin Ser Ser Thr Lys Leu Ser Val Ala Ala Glu Ser Pro Ala Ala 50 55 60 Thr He Ala Thr Asp Asp Trp Gly Lys Val Ser Ala Val Leu Phe Asp 65 70 75 80
Met Asp Gly Val Leu Cys Asn Ser Glu Asp Leu Ser Arg Arg Ala Ala
85 90 95
Val Asp Val Phe Thr Glu Met Gly Val Glu Val Thr Val Asp Asp Phe 100 105 110
Val Pro Phe Met Gly Thr Gly Glu Ala Lys Phe Leu Gly Gly Val Ala
115 120 125
Ser Val Lys Glu Val Lys Gly Phe Asp Pro Asp Ala Ala Lys Lys Arg
130 135 140 Phe Phe Glu He Tyr Leu Asp Lys Tyr Ala Lys Pro Glu Ser Gly He
145 150 155 160
Gly Phe Pro Gly Ala Leu Glu Leu Val Thr Glu Cys Lys Asn Lys Gly
165 170 ' 175
Leu Lys Val Ala Val Ala Ser Ser Ala Asp Arg He Lys Val Asp Ala 180 185 ' 190
Asn Leu Lys Ala Ala Gly Leu Ser Leu Thr Met Phe Asp Ala He Val
195 200 205
Ser Ala Asp Ala Phe Glu Asn Leu Lys Pro Ala Pro Asp He Phe Leu
210 215 220 Ala Ala Ala Lys He Leu Gly Val Pro Thr Ser Glu Cys Val Val He
225 230 235 240
Glu Asp Ala Leu Ala Gly Val Gin Ala Ala Gin Ala Ala Asn Met Arg
245 250 255
Cys He Ala Val Lys Thr Thr Leu Ser Glu Ala He Leu Lys Asp Ala 260 265 270
Gly Pro Ser Met He Arg Asp Asp He Gly Asn He Ser He Asn Asp
275 280 285
He Leu Thr Gly Gly Ser Asp Ser Thr Ser Met 290 295 (2) INFORMATION FOR SEQ ID NO: 271: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 219 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..219
(D) OTHER INFORMATION: / Ceres Seq. ID 1533355 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:271: Met Asp Gly Val Leu Cys Asn Ser Glu Asp Leu Ser Arg Arg Ala Ala 1 5 10 15
Val Asp Val Phe Thr Glu Met Gly Val Glu Val Thr Val Asp Asp Phe
20 25 30
Val Pro Phe Met Gly Thr Gly Glu Ala Lys Phe Leu Gly Gly Val Ala 35 40 45
Ser Val Lys Glu Val Lys Gly Phe Asp Pro Asp Ala Ala Lys Lys Arg
50 55 60
Phe Phe Glu He Tyr Leu Asp Lys Tyr Ala Lys Pro Glu Ser Gly He 65 70 " 75 80 Gly Phe Pro Gly Ala Leu Glu Leu Val Thr Glu Cys Lys Asn Lys Gly
85 90 95
Leu Lys Val Ala Val Ala Ser Ser Ala Asp Arg He Lys Val Asp Ala
100 105 110
Asn Leu Lys Ala Ala Gly Leu Ser Leu Thr Met Phe Asp Ala He Val 115 120 125
Ser Ala Asp Ala Phe Glu Asn Leu Lys Pro Ala Pro Asp He Phe Leu
130 135 140
Ala Ala Ala Lys He Leu Gly Val Pro Thr Ser Glu Cys Val Val He 145 150 155 160 Glu Asp Ala Leu Ala Gly Val Gin Ala Ala Gin Ala Ala Asn Met Arg
165 170 175
Cys He Ala Val Lys Thr Thr Leu Ser Glu Ala He Leu Lys Asp Ala
180 185 190
Gly Pro Ser Met He Arg Asp Asp He Gly Asn He Ser He Asn Asp 195 200 205
He Leu Thr Gly Gly Ser Asp Ser Thr Ser Met
210 215
(2) INFORMATION FOR SEQ ID NO: 272: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1420 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1420
(D) OTHER INFORMATION: / Ceres Seq. ID 1534544 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:272: aaagattctt ggtctccgat ccagtcacct gaagattctc ggagcttctt ttgaccacac 60 actttcaatg gcggatgctg tgaacgctca aactccatcg ctctccgagc aatatcattt 120 ggagaaagaa gtgaagcaag acacaagtgc aaagcctgtt gaagtgaaag aggtggcacc 180 agaagttact acacaagctg aagaggttaa gacggagcaa gctaaggaag aatctcctgt 240 tgaggaagcg gtttctgtag ttgaagagaa gtctgaatct gctcctgaat caacggaagt 300 ggcttctgaq gctcctgctg cagcggaaga caatgctgaa gagactcctg ctgctgctga 360 agaaaataat gacgaaaacg ctagtgaaga agttgctgaa gaaacccctg atgagatcaa 420 gcttgagaca gctcctgctt gatctcatca ggggtttctt tttttttttt ttttttgaat 480 tttttcacca agtgttcgtt cacggcattg cttgtcctcc agtatgagta tctccggtgc 540 tgcagttggt tcaggcagaa atttaagaag agcggtagag tttgggaaaa ctcatgtggt 600 taggcctaaa gggaaacatc aagcaactat tgtctggtta catgggcttg gggacaatgg 660 ctcgagctgg tcccagcttt tggagaccct tccccttcca aatatcaaat ggatttgccc 720 gactgctcct tctcaaccaa taagtttatt tggtggtttt ccctccacag cttggtttga 780 tgttgtggac atcaatgaag atggacctga tgatatggaa ggattggatg tggctgctgc 840 acatgttgca aatctgttgt cgaatgagcc tgctgacatt aaattaggtg ttggaggatt 900 cagcatgggt gcggcgacat ctctatattc tgcaacttgt tttgctctcg gtaaatatgg 960 aaatggcaat ccatacccta tcaatttaag cgcaatcata ggcttaagcg gctggcttcc 1020 ttgtgcaaag acattggctg gcaaactaga agaggaacag atcaagaacc gagctgcatc 1080 gttacccatt gttgtctgtc atggaaaagc tgatgatgtg gtaccgttca agtttgggga 1140 gaaatcttca caggctttgc tttcaaatgg gtttaagaag gtgaccttca aaccttacag 1200 tgcacttggt caccacacaa tcccacagga gttggatgag ttgtgcgcat ggttgacatc 1260 cacgctcagc ctcgaaggtt gatacttcct atgatgtagc tttctgatga aaacccttca 1320 actcttgaga gtttgattga attggatgtt tcaggatttc acaatgtttt cattggaata 1380 tttgtgtaag acacattcgt ctagtagcaa atcttctcct (2) INFORMATION FOR SEQ ID NO: 273: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 146 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..146
(D) OTHER INFORMATION: / Ceres Seq. ID 1534545 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:273: Lys He Leu Gly Leu Arg Ser Ser His Leu Lys He Leu Gly Ala Ser 1 5 10 15
Phe Asp His Thr Leu Ser Met Ala Asp Ala Val Asn Ala Gin Thr Pro
20 25 30
Ser Leu Ser Glu Gin Tyr His Leu Glu Lys Glu val Lys Gin Asp Thr 35 40 45 Ser Ala Lys Pro Val Glu Val Lys Glu Val Ala Pro Glu Val Thr Thr 50 55 60
Gin Ala Glu Glu Val Lys Thr Glu Gin Ala Lys Glu Glu Ser Pro Val 65 70 75 80
Glu Glu Ala Val Ser Val Val Glu Glu Lys Ser Glu Ser Ala Pro Glu 85 90 95
Ser Thr Glu Val Ala Ser Glu Ala Pro Ala Ala Ala Glu Asp Asn Ala
100 105 110
Glu Glu Thr Pro Ala Ala Ala Glu Glu Asn Asn Asp Glu Asn Ala Ser 115 120 125 Glu Glu Val Ala Glu Glu Thr Pro Asp Glu He Lys Leu Glu Thr Ala 130 135 140
Pro Ala 145
(2) INFORMATION FOR SEQ ID NO: 274: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 252 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..252
(D) OTHER INFORMATION: / Ceres Seq. ID 1534546 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 274:
Met Ser He Ser Gly Ala Ala Val Gly Ser Gly Arg Asn Leu Arg Arg 1 5 10 15
Ala Val Glu Phe Gly Lys Thr His Val Val Arg Pro Lys Gly Lys His 20 25 30 Gin Ala Thr He Val Trp Leu His Gly Leu Gly Asp Asn Gly Ser Ser 35 40 45
Trp Ser Gin Leu Leu Glu Thr Leu Pro Leu Pro Asn He Lys Trp He
50 55 60
Cys Pro Thr Ala Pro Ser Gin Pro He Ser Leu Phe Gly Gly Phe Pro 65 70 75 80
Ser Thr Ala Trp Phe Asp Val Val Asp He Asn Glu Asp Gly Pro Asp 85 90 95 Asp Met Glu Gly Leu Asp Val Ala Ala Ala His Val Ala Asn Leu Leu
100 105 110
Ser Asn Glu Pro Ala Asp He Lys Leu Gly Val Gly Gly Phe Ser Met 115 120 125 Gly Ala Ala Thr Ser Leu Tyr Ser Ala Thr Cys Phe Ala Leu Gly Lys 130 135 140
Tyr Gly Asn Gly Asn Pro Tyr Pro He Asn Leu Ser Ala He He Gly 145 150 155 160
Leu Ser Gly Trp Leu Pro Cys Ala Lys Thr Leu Ala Gly Lys Leu Glu 165 170 175
Glu Glu Gin He Lys Asn Arg Ala Ala Ser Leu Pro He Val Val Cys
180 185 190
His Gly Lys Ala Asp Asp Val Val Pro Phe Lys Phe Gly Glu Lys Ser 195 200 205 Ser Gin Ala Leu Leu Ser Asn Gly Phe Lys Lys Val Thr Phe Lys Pro 210 215 220
Tyr Ser Ala Leu Gly His His Thr He Pro Gin Glu Leu Asp Glu Leu 225 230 235 240
Cys Ala Trp Leu Thr Ser Thr Leu Ser Leu Glu Gly 245 250
(2) INFORMATION FOR SEQ ID NO: 275: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1534547 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 275: Met Glu Gly Leu Asp Val Ala Ala Ala His Val Ala Asn Leu Leu Ser 1 5 10 15 Asn Glu Pro Ala Asp He Lys Leu Gly Val Gly Gly Phe Ser Met Gly
20 25 30
Ala Ala Thr Ser Leu Tyr Ser Ala Thr Cys Phe Ala Leu Gly Lys Tyr
35 40 " 45
Gly Asn Gly Asn Pro Tyr Pro He Asn Leu Ser Ala He He Gly Leu 50 55 60
Ser Gly Trp Leu Pro Cys Ala Lys Thr Leu Ala Gly Lys Leu Glu Glu 65 70 75 80
Glu Gin He Lys Asn Arg Ala Ala Ser Leu Pro He Val Val Cys His 85 90 95 Gly Lys Ala Asp Asp Val Val Pro Phe Lys Phe Gly Glu Lys Ser Ser
100 105 110
Gin Ala Leu Leu Ser Asn Gly Phe Lys Lys Val Thr Phe Lys Pro Tyr
115 120 125
Ser Ala Leu Gly His His Thr He Pro Gin Glu Leu Asp Glu Leu Cys 130 135 140
Ala Trp Leu Thr Ser Thr Leu Ser Leu Glu Gly 145 150 155
(2) INFORMATION FOR SEQ ID NO: 276: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1592 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1592 (D) OTHER INFORMATION: / Ceres Seq. ID 1567172 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:276: gtagtctctc tttttataac cacttctcga aaactgaaac ctttgtagag agaacccata 60 gttcgataaa acattctttt tgcaactgag acttggcaac ttggttttac tcaaagtaag 120 atttcttctt gttgatggtg ataagttcaa tatgatgaaa agtttggcta gtgcggttgg 180 agggaagacg gcgagggcat gtgatagctg cgtgaagagg cgggcacgtt ggtattgcgc 240 aGctgatgat gcctttcttt gccatgcttg tgacggttcg gtccactcgg caaaccctct 300 tgctcgtaga cacgagagag ttcgcttgaa atcggctagc gccggaaaat atcgccatgc 360 ctcgccgcct caccaagcca cgtggcatca gggatttaca cgtaaagctc ggaccccacg 420 tggaggcaag aagagccaca cgatggtttt tcatgatctt gtgccggaga tgagcacgga 480 ggatcaagcg gagagttacg aggtggaaga gcagctcata tttgaggtgc cggtgatgaa 540 ctcgarggtt gaggagcaat gctttaacca atccctggag aaacagaatg agtttccaat 600 gatgccctta agtttcaaga gtagtgacga agaagatgac gacaacgctg agagttgtct 660 gaatggtttg ttcccaaccg acatggaact agctcagttc acagctgacg tggagactct 720 actcggtgga ggggatcgag agtttcattc catagaagaa ctagggttag gtgagatgtt 780 aaagatcgaa aaagaggagg tggaggaaga ggaaggagtt gtgacaagag aagtgcatga 840 tcaagatgaa ggtgatgaga catccccatt tgaaataagc tttgactacg agtacacaca 900 caagaccaca ttcgatgaag gagaagaaga tgagaaagaa gacgtgatga agaatgtgat 960 ggagatggga gtgaatgaga tgagtggtgg gattaaagaa gagaagaagg agaaggctct 1020 tatgcttaga ttggactatg aatcagtcat ttccacttgg ggaggccaag ggatcccatg 1080 gaccgcccgg gtgccatctg aaatagacct cgacatggtt tgtttcccaa cccataccat 1140 gggtgaaagt ggagcagagg ctcatcatca caaccacttc cgcggcctaG ggttacacct 1200 aggagatgct ggggatggag gaagagaggc tagggtttca agataccgag agaaaaggag 1260 gacaaggttg ttctccaaga agataaggta cgaggtacgt aaattgaatg cagataaaag 1320 gcctcgcatg aaaggaaggt tcgtcaagag atcttcaatt ggtgttgctc actaaagaac 1380 ttaattaatt atggatatta aattactttg ctctcatctt gcttttttgt tgctatagtt 1440 ttggtgattg ttagctttct ttttctgcat tcatagagaa ttttgcacgt ttttgtgagc 1500 tacgtatgta cataaatata tcaccaaaaa atgtgactat cttgtaagca ctgatttata 1560 tagtcgatat aacgtgaatt ttgattgctg gt (2) INFORMATION FOR SEQ ID NO: 277: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 407 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..407 (D) OTHER INFORMATION: / Ceres Seq. ID 1567173
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:277: Met Met Lys Ser Leu Ala Ser Ala Val Gly Gly Lys Thr Ala Arg Ala 1 5 10 15
Cys Asp Ser Cys Val Lys Arg Arg Ala Arg Trp Tyr Cys Ala Ala Asp 20 25 30
Asp Ala Phe Leu Cys His Ala Cys Asp Gly Ser Val His Ser Ala Asn
35 40 45
Pro Leu Ala Arg Arg His Glu Arg Val Arg Leu Lys Ser Ala Ser Ala 50 55 60 Gly Lys Tyr Arg His Ala Ser Pro Pro His Gin Ala Thr Trp His Gin 65 70 75 80
Gly Phe Thr Arg Lys Ala Arg Thr Pro Arg Gly Gly Lys Lys Ser His
85 90 95
Thr Met Val Phe His Asp Leu Val Pro Glu Met Ser Thr Glu Asp Gin 100 105 110
Ala Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro Val
115 120 125
Met Asn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys
130 135 140 Gin Asn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser Asp Glu
145 150 155 160
Glu Asp Asp Asp Asn Ala Glu Ser Cys Leu Asn Gly Leu Phe Pro Thr 165 170 175
Asp Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly
180 185 190
Gly Gly Asp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu 195 200 205
Met Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Glu Gly Val Val
210 215 220
Thr Arg Glu Val His Asp Gin Asp Glu Gly Asp Glu Thr Ser Pro Phe 225 230 235 240 Glu He Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu
245 250 255
Gly Glu Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met
260 265 270
Gly Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys 275 280 285
Ala Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly
290 295 ^ 300
Gly Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu 305 310 315 320 Asp Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu
325 330 " 335
Ala His His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly Asp
340 345 350
Ala Gly Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr Arg Glu Lys 355 360 365
Axg Arg Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg Lys
370 375 380
Leu Asn Ala Asp Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys Arg 385 390 395 400 Ser Ser He Gly Val Ala His
405 (2) INFORMATION FOR SEQ ID NO: 278: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 406 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..406
(D) OTHER INFORMATION: / Ceres Seq. ID 1567174 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 278: Met Lys Ser Leu Ala Ser Ala Val Gly Gly Lys Thr Ala Arg Ala Cys 1 5 10 15
Asp Ser Cys Val Lys Arg Arg Ala Arg Trp Tyr Cys Ala Ala Asp Asp
20 25 30
Ala Phe Leu Cys His Ala Cys Asp Gly Ser Val His Ser Ala Asn Pro 35 40 45 Leu Ala Arg Arg His Glu Arg Val Arg Leu Lys Ser Ala Ser Ala Gly 50 55 60
Lys Tyr Arg His Ala Ser Pro Pro His Gin Ala Thr Trp His Gin Gly 65 70 75 80
Phe Thr Arg Lys Ala Arg Thr Pro Arg Gly Gly Lys Lys Ser His Thr 85 90 95
Met Val Phe His Asp Leu Val Pro Glu Met Ser Thr Glu Asp Gin Ala
100 105 110
Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro Val Met 115 120 125 Asn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys Gin 130 135 140
Asn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser Asp Glu Glu 145 150 155 160
Asp Asp Asp Asn Ala Glu Ser Cys Leu Asn Gly Leu Phe Pro Thr Asp
165 170 175
Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly Gly 180 185 190
Gly Asp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu Met
195 200 205
Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Glu Gly Val Val Thr
210 215 220 Arg Glu Val His Asp Gin Asp Glu Gly Asp Glu Thr Ser Pro Phe Glu
225 230 235 240
He Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu Gly
245 250 255
Glu Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met Gly 260 265 270
Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys Ala
275 280 285
Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly Gly
290 295 300 Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu Asp
305 310 315 320
Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu Ala
325 330 335
His His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly Asp Ala 340 345 350
Gly Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr Arg Glu Lys Arg
355 360 365
Arg Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg Lys Leu 370 375 380 Asn Ala Asp Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys Arg Ser 385 390 395 400
Ser He Gly Val Ala His
405 (2) INFORMATION FOR SEQ ID NO: 279: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 310 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..310
(D) OTHER INFORMATION: / Ceres Seq. ID 1567175 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 279:
Met Val Phe His Asp Leu Val Pro Glu Met Ser Thr Glu Asp Gin Ala 1 5 10 15
Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro Val Met 20 25 30 Asn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys Gin 35 40 45
Asn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser Asp Glu Glu
50 55 60
Asp Asp Asp Asn Ala Glu Ser Cys Leu Asn Gly Leu Phe Pro Thr Asp 65 70 75 80
Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly Gly
85 90 95
Gly Asp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu Met 100 105 110 Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Glu Gly Val Val Thr 115 120 125
Arg Glu Val His Asp Gin Asp Glu Gly Asp Glu Thr Ser Pro Phe Glu 130 135 140
He Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu Gly
145 150 155 160
Glu Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met Gly 165 170 175
Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys Ala 180 185 190
Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly Gly 195 200 205
Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu Asp 210 215 220
Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu Ala
225 230 235 240
His His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly Asp Ala 245 250 255
Gly Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr Arg Glu Lys Arg
260 265 270
Arg Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg Lys Leu
275 280 285
Asn Ala Asp Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys Arg Ser
290 295 300
Ser He Gly Val Ala His 305 310
(2) INFORMATION FOR SEQ ID NO: 280: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 520 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..520
(D) OTHER INFORMATION: / Ceres Seq. ID 15675o5 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 280: aaaaattccg cagaattgat tatcgtcatt tcgttaagga tctctgtggg gtttgatcga 60 atttcatagc gaaggagaga gtgagagaga gattgaagca gtaatggcag gaacatctgg 120 attgctcaac gcagtgaagc caaagatcca aacgattgat attcaggccg ccgctggatg 180 gggaatcgcc gccgcagccg gtgccatctg ggtcgtccaa ccatttggtt ggataaagaa 240 gacattcatt gacccacccc caactgaaga gaagrgagat atcaccaaga ttcaagacta 300 agtgaagagt tttccagttt ctaagtttgt taccgcctct ttggcgtgga gctgaataaa 360 ttttggttct tttctggggc tttctggttt catttcttca atgtttgact gatttgtctt 420 ctcaaatgtt ataacaaaca agaaaagcac ttactccaag ttacttgaaa agagaaccca 480 ttttgcattt atcatgagtt attatttTcc atgtcaaagt
(2) INFORMATION FOR SEQ ID NO: 281: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 57 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..57 (D) OTHER INFORMATION: / Ceres Seq. ID 1567536
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:281: Met Ala Gly Thr Ser Gly Leu Leu Asn Ala Val Lys Pro Lys He Gin 1 5 10 15
Thr He Asp He Gin Ala Ala Ala Gly Trp Gly He Ala Ala Ala Ala
20 25 30
Gly Ala He Trp Val Val Gin Pro Phe Gly Trp He Lys Lys Thr Phe 35 40 45 He Asp Pro Pro Pro Thr Glu Glu Lys
50 55
(2) INFORMATION FOR SEQ ID NO: 282: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 765 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..765
(D) OTHER INFORMATION: / Ceres Seq. ID 1569689 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:282: aaccaaaaat ttcttcgtct ctgtctccaa aatcgaatca aaatctctaa agtttcaatt 60 tttttgttct gttctttttt ttttttaaag aatggcttca atttctgcaa ctttgccttc 120 gccattgtta ctcacacaga gaaaatccaa tctcacatcg attcaaaaac tcccattttc 180 tctaactcga ggtacgaatg atctttctcc attatctctt actcgaaacc ctagcagcat 240 cagtctgatg gtgaaagcta gtggagaaag ctcagattca tcgactgatc tcgacgttgt 300 tagtacgatt cagaatgttt gggataagtc tgaagatagg ttaggtctta ttggtttggg 360 ttttRgctgg tattgtagct ctttgggcat cattgaatct catcacggca attgacaaat 420 tgsccgttat ctcgagcgga ttcgaactag ttggtatctt gttctccacg tggttcacat 480 atcgatatct cttgttcaaa ccggacagac aggagctttc gaaaattgtc aagaaatcag 540 tagcggatat acttggccag tgaaccttgt gtgtgtgata atacTttcat ctttggaaga 600 tgatttgttt gcaagtttgt aaaattacat gacagggtgg ttgttgtttc tagtccaata 660 atgtcatgca tttgaaacct gtaaatactt tattgttggt ttttggttgt gagcaaaatc 720 aatcttttct aatttcaaag attctctttt atgattatac gtttt (2) INFORMATION FOR SEQ ID NO:283: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 66 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..66
(D) OTHER INFORMATION: / Ceres Seq. ID 1569690 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:283: Asn Gin Lys Phe Leu Arg Leu Cys Leu Gin Asn Arg He Lys He Ser 1 5 10 15
Lys Val Ser He Phe Leu Phe Cys Ser Phe Phe Phe Leu Lys Asn Gly
20 25 30
Phe Asn Phe Cys Asn Phe Ala Phe Ala He Val Thr His Thr Glu Lys 35 40 45
He Gin Ser His He Asp Ser Lys Thr Pro He Phe Ser Asn Ser A.rg
50 55 60
Tyr Glu 65 (2) INFORMATION FOR SEQ ID NO:284: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 107 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..107 (D) OTHER INFORMATION: / Ceres Seq. ID 1569691
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:284: Met Ala Ser He Ser Ala Thr Leu Pro Ser Pro Leu Leu Leu Thr Gin 1 5 10 15
Arg Lys Ser Asn Leu Thr Ser He Gin Lys Leu Pro Phe Ser Leu Thr
20 25 30
Arg Gly Thr Asn Asp Leu Ser Pro Leu Ser Leu Thr Arg Asn Pro Ser 35 40 45
Ser He Ser Leu Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser
50 55 60
Thr Asp Leu Asp Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser 65 70 75 80 Glu Asp Arg Leu Gly Leu He Gly Leu Gly Phe Xaa Trp Tyr Cys Ser
85 90 95
Ser Leu Gly He He Glu Ser His His Gly Asn
100 105
(2) INFORMATION FOR SEQ ID NO: 285: (l) SEQUENCE CHARACTERISTICS: iA) LENGTH: 55 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
A) NAME/KEY: peptide B) LOCATION: 1..55
(D) OTHER INFORMATION: / Ceres Seq. ID 1569692 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:285:
Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser Thr Asp Leu Asp 1 5 10 15
Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser Glu Asp Arg Leu 20 25 30 Gly Leu He Gly Leu Gly Phe Xaa Trp Tyr Cys Ser Ser Leu Gly He 35 40 45
(2) INFORMATION FOR SEQ ID NO: 286: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 782 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single vD) TOPOLOGY: linear (n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..782
(D) OTHER INFORMATION: / Ceres Seq. ID 1571042 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:286: atcaaccaaa acaaaacata aaaaacaagt ggaagcttta aaacgagagg gagagagcaa 60 aaatggcgac gtcgggaacg tacgtgacgg aagttccgct aaaaggatcg gccgagaaat 120 actacaagag gtggaagaac gagaaccatg tcttccctga tgctatcggc caccacatcc 180 aaaatgttac cgttcacgaa ggcgaacatg actctcacgg Gtctatcagg agttggaact 240 acacatggga tggaaaggag gaggtgttca aggagagaag agagatagac gatgagacca 300 aaacgttgac gttaagagga cttgagggtc acgtgatgga gcagctcaaa gtgtacgacg 360 tcgtctacca attcattccc aaatctgagg atacctgcat cggcaaaatc actttaatat 420 gggagaagcg caacgatgat tccccagaac caagcggcta catgaaattc gtcaagagct 480 tggttgctga catgggaaac cacgttagca aaacttaatc atcattccca cagtcgtcgt 540 catcatcatc atcatcatca tcatcatcat catcatcatc atcatcatca tcatcatcat 600 catcatcatc atcatcacta tctcgattta taagttaaga tgttttcagt ataataaatg 660 gggtcttgtg gatcgttcat ttctatgtgt aaaccgtttg gttctgtatg atgcttcgat 720 atattgttat gttcatgatc atatgtcggg ttcgatataa tgattcttaa gattaattta 780 ct (2) INFORMATION FOR SEQ ID NO: 287: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 ammo acids (B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..151
(D) OTHER INFORMATION: / Ceres Seq. ID 1571043 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:287: Met Ala Thr Ser Gly Thr Tyr Val Thr Glu Val Pro Leu Lys Gly Ser 1 5 " 10 15
Ala Glu Lys Tyr Tyr Lys Arg Trp Lys Asn Glu Asn His Val Phe Pro
20 25 30
Asp Ala He Gly His His He Gin Asn Val Thr Val His Glu Gly Glu
35 40 45
His Asp Ser His Gly Ser He Arg Ser Trp Asn Tyr Thr Trp Asp Gly
50 55 60
Lys Glu Glu Val Phe Lys Glu Arg Arg Glu He Asp Asp Glu Thr Lys 65 70 75 80
Thr Leu Thr Leu Arg Gly Leu Glu Gly His Val Met Glu Gin Leu Lys
85 90 95
Val Tyr Asp Val Val Tyr Gin Phe He Pro Lys Ser Glu Asp Thr Cys
100 105 110
He Gly Lys He Thr Leu He Trp Glu Lys Arg Asn Asp Asp Ser Pro
115 120 125
Glu Pro Ser Gly Tyr Met Lys Phe Val Lys Ser Leu Val Ala Asp Met
130 135 140
Gly Asn His Val Ser Lys Thr 145 150
(2) INFORMATION FOR SEQ ID NO: 288: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 718 bare pairs
(B) TYPE: nucleic ac_d
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..718
(D) OTHER INFORMATION: / Ceres Seq. ID 157107 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 288: attcaaagac atacaaaata attgagtttt ttttttttaa ttagaaacaa atggggttga 60 gtggtgttct tcatgtggag gttgaggtta agtctccggc tgaaaagttc tgggtagccc 120 tcggcgacgg catcaatctc ttccccaaag ctttccctaa cgactacaaa accatccaag 180 ttctagccgg cgacggcaac gctcctggct ccattcgcct cattacttat ggagaaggat 240 ctccactggt gaagatatcg gcggagagga tcgaagcagt ggatttggag aacaaaagca 300 tgtcatacag catcattggc ggcgaaatgt tggagtacta caaaacgttc aaaggaacca 360 tcaccgttat tcctaagaac ggtggcagcc ttctgaaatg gtctggtgag tttgagaaga 420 ccgcccatga gattgatgac ccacacgtca tcaaggactt tgctgtcaag aacttcaaag 480 agatagatga gtatctcctt aagcaaacta gtgcctaaca ctagaacctt taaattatat 540 Maagagggtt cgatcgtctc tataagattt ttctaattaa gaagttgaat aaagtggaac 600 ctctttatga atatccaagt ttgtgatttc ggagtttatg cagcctagta ggccataagc 660 tttttacaaa agccaattta gtcgaacatt ttgaaaaaat cgaacctttt ggtaaagc (2) INFORMATION FOR SEQ ID NO: 289:
.1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide (IX) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 1571080 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 289: Met Gly Leu Ser Gly Val Leu His Val Glu Val Glu Val Lys Ser Pro 1 5 10 15
Ala Glu Lys Phe Trp Val Ala Leu Gly Asp Gly He Asn Leu Phe Pro
20 25 30
Lys Ala Phe Pro Asn Asp Tyr Lys Thr He Gin Val Leu Ala Gly Asp 35 40 45 Gly Asn Ala Pro Gly Ser He Arg Leu He Thr Tyr Gly Glu Gly Ser 50 55 60
Pro Leu Val Lys He Ser Ala Glu Arg He Glu Ala Val Asp Leu Glu 65 70 75 80
Asn Lys Ser Met Ser Tyr Ser He He Gly Gly Glu Met Leu Glu Tyr 85 90 95
Tyr Lys Thr Phe Lys Gly Thr He Thr Val He Pro Lys Asn Gly Gly
100 105 110
Ser Leu Leu Lys Trp Ser Gly Glu Phe Glu Lys Thr Ala His Glu He 115 120 125 Asp Asp Pro His Val He Lys Asp Phe Ala Val Lys Asn Phe Lys Glu 130 135 140
He Asp Glu Tyr Leu Leu Lys Gin Thr Ser Ala 145 150 155
(2) INFORMATION FOR SEQ ID NO: 290: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 808 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..808
(D) OTHER INFORMATION: / Ceres Seq. ID 1572097 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 290: atcaaccaaa acaaaacata aaaaacaagt ggaagcttta aaacgagagg gatagagcaa 60 aaatggcgac gtcgggaacg tacgtgacgg aagttccgct aaaaggatcg gccgagaaat 120 actacaagag gtggaagaac gagaaccatg tcttccctga tgctatcggc caccacatcc 180 aaaatgttac cgttcacgaa ggcgaacatg actctcacgg gtctatcagg agttggaact 240 acacatggga tggaaaggag gaggtgttca aggagagaag agagatagac gatgagacca 300 aaacgttgac gttaagagga cttgagggtc acgtgatgga gcagctcaaa gtgtacgacg 360 tcgtctacca attcattccc aaatctgagg atacctgcat cggcaaaatc actttaatat 420 gggagaagcg caacgatgat tccccagaac caagcggcta catgaaattc gtcaagagct 480 tggttgctga catgggaaac cacgttagCC CcAAAAAAAA AAAAAAaaaa cttaatcatc 540 attcccacag tcgtcgtcat catcatcatc atcatcatca tcatcatcat catcatcatc 600 atcatcatca tcatcatcat catcatcatc atcactatct cgatttataa gttaagatgt 660 tttcagtata ataaatgggg tcttgtggat cgttcatttc tatgtgtaaa ccgtttggtt 720 ctgtatgatg cttcgatata ttgttatgtt catgatcata tgtcgggttc gatataatga 780 ttcttaagat taatttacta cacatttc (2) INFORMATION FOR SEQ ID NO: 291: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 195 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..195 (D) OTHER INFORMATION: / Ceres Seq. ID 1572098
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 291: Met Ala Thr Ser Gly Thr Tyr Val Thr Glu Val Pro Leu Lys Gly Ser 1 5 10 15
Ala Glu Lys Tyr Tyr Lys Arg Trp Lys Asn Glu Asn His Val Phe Pro
20 25 30
Asp Ala He Gly His His He Gin Asn Val Thr Val His Glu Gly Glu 35 40 45
His Asp Ser His Gly Ser He Arg Ser Trp Asn Tyr Thr Trp Asp Gly
50 55 60
Lys Glu Glu Val Phe Lys Glu Arg Arg Glu He Asp Asp Glu Thr Lys 65 70 " 75 80 Thr Leu Thr Leu Arg Gly Leu Glu Gly His Val Met Glu Gin Leu Lys
85 90 95
Val Tyr Asp Val Val Tyr Gin Phe He Pro Lys Ser Glu Asp Thr Cys
100 105 110
He Gly Lys He Thr Leu He Trp Glu Lys Arg Asn Asp Asp Ser Pro " 115 120 125
Glu Pro Ser Gly Tyr Met Lys Phe Val Lys Ser Leu Val Ala Asp Met
130 135 140
Gly Asn His Val Ser Pro Lys Lys Lys Lys Lys Lys Leu Asn His His 145 150 155 160 Ser His Ser Arg Arg His His His His His His His His His His His
165 170 175
His His His His His His His his His His His His His His His Tyr
180 185 190
Leu Asp Leu 195
(2) INFORMATION FOR SEQ ID NO:292: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 104 ammo acids
(B) TYPE: ammo acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..104
(D) OTHER INFORMATION: / Ceres Seq. ID 1572099 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:292: Met Glu Gin Leu Lys Val Tyr A.sp Val Val Tyr Gin Phe He Pro Lys 1 5 10 15 Ser Glu Asp Thr Cys He Gly Lys He Thr Leu He Trp Glu Lys Arg
20 25 30
Asn Asp Asp Ser Pro Glu Pro Ser Gly Tyr Met Lys Phe Val Lys Ser
35 40 45
Leu Val Ala Asp Met Gly Asn His Val Ser Pro Lys Lys Lys Lys Lys 50 55 60
Lys Leu Asn His His Ser His Ser Arg Arg His His His His His His 65 70 75 80
His His His His His His His His His His His His His His His His 85 90 95 His His His His Tyr Leu Asp Leu
100 (2) INFORMATION FOR SEQ ID NO:293: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 583 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..583
(D) OTHER INFORMATION: / Ceres Seq. ID 1572890 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:293: aaaaacaaaa ataaaaaaaa catcgcacaa gaaaataaaa gatttgtaga atcaactaag 60 aaaatggcta gcactatgat gactacattg cctcagttca atggtcttcg agccaccaaa 120 atctctgcag ctcctgtaca aggcctggca agtgttcagc ccatgagacg caagggaaat 180 ggagctttgg gtgcaaagtg tgacttcatc ggttcatcaa caaatctgat aatggtaacg 240 tcgacgaccc tgattttgtt cgcggggaga ttcggacttg cgccatcagc caataggaag 300 gcgacagctg gacttaggtt ggaggcacgt gactcaggtc tacaaacggg tgacccggcc 360 gggttcacgc ttgcggacac tttggcttgt ggcaccgttg gtcatatcat cggtgtagga 420 gttgtccttg gccttaaaaa cattggtgct atttgaagtt cctaaagctc ttttatttgt 480 atttgtaaaa Atttgtagat ttttataaca atattctcat gcacctgaac gagatctaat 540 ggattttaca agtctttatg tttatcttat aatgttgtat cgc (2) INFORMATION FOR SEQ ID NO: 294: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..151
,D) OTHER INFORMATION: / Ceres Seq. ID 1572891 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 294:
L Lyyss Asn Lys Asn Lys Lys Asn He Ala Gin Glu Asn Lys Arg Phe Val
1 5 10 15
Glu Ser Thr Lys Lys Met Ala Ser Thr Met Met Thr Thr Leu Pro Gin 20 25 30
Phe Asn Gly Leu Arg Ala Thr Lys He Ser Ala Ala Pro Val Gin Gly 35 40 45
Leu Ala Ser Val Gin Pro Met Arg Arg Lys Gly Asn Gly Ala Leu Gly 50 55 60
Ala Lys Cys Asp Phe He Gly Ser Ser Thr Asn Leu He Met Val Thr
65 70 75 80
Ser Thr Thr Leu He Leu Phe Ala Gly Arg Phe Gly Leu Ala Pro Ser 85 90 95
Ala Asn Arg Lys Ala Thr Ala Gly Leu Arg Leu Glu Ala Arg Asp Ser 100 105 110
Gly Leu Gin Thr Gly Asp Pro Ala Gly Phe Thr Leu Ala Asp Thr Leu 115 120 125
Ala Cys Gly Thr Val Gly His He He Gly Val Gly Val Val Leu Gly 130 135 140
Leu Lys Asn He Gly Ala He
145 150
(2) INFORMATION FOR SEQ ID NO:295:
( J ) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 130 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..130
(D) OTHER INFORMATION: / Ceres Seq. ID 1572892 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 295:
Met Ala Ser Thr Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg 1 5 10 15
Ala Thr Lys He Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin 20 25 30 Pro Met Arg Arg Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe 35" ' 40 45
He Gly Ser Ser Thr Asn Leu He Met Val Thr Ser Thr Thr Leu He 50 55 60
Leu Phe Ala Gly Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala
65 70 75 80
Thr Ala Gly Leu Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly 85 90 95
Asp Pro Ala Gly Phe Thr Leu Ala Asp Thr Leu Ala Cys Gly Thr Val 100 105 110
Gly His He He Gly Val Gly Val Val Leu Gly Leu Lys Asn He Gly 115 120 125
Ala He 130
(2) INFORMATION FOR SEQ ID NO:296:
(l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 126 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear in) MOLECULE TYPE: peptide
(IX) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..126
(D) OTHER INFORMATION: / Ceres Seq. ID 1572893 (xi) SEQUENCE DESCRIPTION: SEQ ID O:296: Met Met Thr Thr Leu Pro Gin Phe Asn Gly Leu Arg Ala Thr Lys He 1 5 10 15
Ser Ala Ala Pro Val Gin Gly Leu Ala Ser Val Gin Pro Met Arg Arg
20 25 30
Lys Gly Asn Gly Ala Leu Gly Ala Lys Cys Asp Phe He Gly Ser Ser
35 40 45
Thr Asn Leu He Met Val Thr Ser Thr Thr Leu He Leu Phe Ala Gly
50 55 60
Arg Phe Gly Leu Ala Pro Ser Ala Asn Arg Lys Ala Thr Ala Gly Leu 65 70 75 80
Arg Leu Glu Ala Arg Asp Ser Gly Leu Gin Thr Gly Asp Pro Ala Gly
85 90 95
Phe Thr Leu Ala AAsspp Thr Leu Ala Cys Gly Thr Val Gly His He He 100 105 110
Gly Val Gly Val Val Leu Gly Leu Lys Asn He Gly Ala He
115 120 125 .2) INFORMATION FOR SEQ ID NO: 297: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 748 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE DNA (genomic)
(ix) FEATURE:
(A) NAME/KEY
(B) LOCATION 1..748 (D) OTHER INFORMATION: / Ceres Seq ID 1573606
(xi! SEQUENCE DESCRIPTION: SEQ ID NO: 297: ccttctcact tcaaattcat aatctctcta cttctctctc tctctaaatt caaaaatggc 60 gaaactggtg atgttgttgg ttctttgtat cttaccggcg ataGccatgg cggcaaggag 120 gagtaatatt ggaaagaata caatggtggt tcaaggtagc acttactgtg acatttgcaa 180 attcggcttc gagactcctg aatcctccta cttcatcccc ggtgcaacgg tgaagctatc 240 atgcaaagac aggaagacaa tggaagaggt ttacacagac aaagctgtat cggacaaaga 300 aggaaagtat aagttcattg tccacgacga tcacagagac cagatgtgcg atgttttgct 360 tgtgaaaagc tcggataaaa cctgctctaa aatctccgtt ggacgtgaga agtctcgtgt 420 gatcttgaac cattacagtg gcattgcctc gcagatcaga catgctaaca acatgggatt 480 cgagaaagaa gtgagtgatg tgttctgctc tgctttgttt cagaagtata tggttgatga 540 agatgaggat gatattaaaa accatctcta atctctctgt ttaatcttat gatctgctgt 600 tttcttcatt aatgagtttc gagttatgga agagatatat ttgtatttgt ttgattactt 660 atttgttgtc tttagagatg ttgactctgg tgatcggata actatctgtt tgtgtaagct 720 tcttatatat tgatgtgtca tttccttg (2) INFORMATION FOR SEQ ID NO: 298: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 171 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..171
(D) OTHER INFORMATION: / Ceres Seq. ID 1573607 (xi ) SEQUENCE DESCRIPTION: SEQ ID NO: 298: Met Ala Lys Leu Val Met Leu Leu Val Leu Cys He Leu Pro Ala He 1 5 10 15
Ala Met Ala Ala Arg Arg Ser Asn He Gly Lys Asn Thr Met Val Val
20 25 30
Gin Gly Ser Thr Tyr Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro 35 40 45
Glu Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys
50 55 60
Asp Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp 65 70 75 80 Lys Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His Arg Asp Gin
85 90 95
Met Cys Asp Val Leu Leu Val Lys Ser Ser A_sp Lys Thr Cys Ser Lys
100 105 110
He Ser Val Gly Arg Glu Lys Ser Arg Val He Leu Asn His Tyr Ser 115 120 125
Gly He Ala Ser Gin He Arg His Ala Asn Asn Met Gly Phe Glu Lys
130 135 140
Glu Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val 145 150 155 160 Asp Glu Asp Glu Asp Asp He Lys Asn His Leu
165 170
(2) INFORMATION FOR SEQ ID NO:299: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 166 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..166
(D) OTHER INFORMATION: / Ceres Seq. ID 1573608 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:299:
Met Leu Leu Val Leu Cys He Leu Pro Ala He Ala Met Ala Ala Arg 1 5 10 15
Arg Ser Asn He Gly Lys Asn Thr Met Val Val Gin Gly Ser Thr Tyr
20 25 30
Cys Asp He Cys Lys Phe Gly Phe Glu Thr Pro Glu Ser Ser Tyr Phe 35 40 45 He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys Asp Arg Lys Thr Met 50 55 60
Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp Lys Glu Gly Lys Tyr 65 70 75 80
Lys Phe He Val His Asp Asp His Arg Asp Gin Met Cys Asp Val Leu 85 90 95
Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys He Ser Val Gly Arg 100 105 110 Glu Lys Ser Arg Val He Leu Asn His Tyr Ser Gly He Ala Ser Gin
115 120 125
He Arg His Ala Asn Asn Met Gly Phe Glu Lys Glu Val Ser Asp Val
130 135 140
Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val Asp Glu Asp Glu Asp
145 150 155 160 Asp He Lys Asn His Leu 165
(2) INFORMATION FOR SEQ ID NO: 300: (I; SEQUENCE CHARACTERISTICS:
(A) LENGTH: 154 ammo acids
(B) TYPE: mino acid ιC) STRANDEDNESS:
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide
( x) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..154
(D) OTHER INFORMATION: : / Ceres Seq. ID 1573609
(XI) SEQUENCE DESCRIPTION: SEQ _ [D NO:300:
Met Ala Ala Arg Arg Ser A_sn He Gly Lys Asn Thr Met V il Val Gin
5 10 15
Gly Ser Thr Tyr Cys Asp He Cys Lys Pne Gly Phe Glu Thr Pro Glu 20 25 30
Ser Ser Tyr Phe He Pro Gly Ala Thr Val Lys Leu Ser Cys Lys Asp 35 40 45
Arg Lys Thr Met Glu Glu Val Tyr Thr Asp Lys Ala Val Ser Asp Lys 50 55 60
Glu Gly Lys Tyr Lys Phe He Val His Asp Asp His Arg Asp Gin Met
65 70 75 80
Cys Asp Val Leu Leu Val Lys Ser Ser Asp Lys Thr Cys Ser Lys He 85 90 95
Ser Val Gly Arg Glu Lys Ser A.rg Val He Leu Asn His Tyr Ser Gly 100 105 110
He Ala Ser Gin He Arg His Ala Asn Asn Met Gly Phe Glu Lys Glu 115 120 125
Val Ser Asp Val Phe Cys Ser Ala Leu Phe Gin Lys Tyr Met Val Asp 130 135 140
Glu Asp Glu Asp Asp He Lys Asn His Leu
145 150
(2) INFORMATION FOR SEQ ID NO:301:
(l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 704 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: DNA (genomic) ( X) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..704 (D) OTHER INFORMATION: / Ceres Seq. ID 1573861
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 301: aaaaaatcga atcaaaatct ctaaagtttc aatttttttg ttctgttctt tttttttttt 60 taaagaatgg cttcaatttc tgcaactttg ccttcgccat tgttactcac acagagaaaa 120 tccaatctca catcgattca aaaactccca ttttctctaa ctcgaggtac gaatgatctt 180 tctccattat ctcttactcg aaaccctagc agcatcagtc tgatggtgaa agctagtgga 240 gaaagctcag attcatcgac tgatctcgac gttgttagta cgattcagaa tgtttgggat 300 aagtctgaaa ataggttagg tcttattggt ttgggttttg ctggtattgt agctctttgg 360 gcatcattga atctcatcac ggcaattgac aaattgcccg ttatctcgag cggattcgaa 420 ctagttggta tcttgttctc cacgtggttc acatatcgat atctcttgtt caaaccggac 480 agacaggagc tttcgaaaat tgtcaagaaa tcagtagcgg atatacttgg cAcagtgaac 540 cttgtgtgtg tgataatact tcatctttgg aagatgattt gtttgcaagt ttgtaaaatt 600 acatgacagg gtggttgttg tttctagtcc aataatgtca tgcatttgaa acctgtaaat 660 actttattgt tggtttttgg ttgtgagcaa aatcaatctt ttct (2) INFORMATION FOR SEQ ID NO: 302: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 179 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..179
(D) OTHER INFORMATION: / Ceres Seq. ID 1573862 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 302: Met Ala Ser He Ser Ala Thr Leu Pro Ser Pro Leu Leu Leu Thr Gin 1 5 10 15
Arg Lys Ser Asn Leu Thr Ser He Gin Lys Leu Pro Phe Ser Leu Thr
20 25 30
Arg Gly Thr Asn Asp Leu Ser Pro Leu Ser Leu Thr Arg Asn Pro Ser 35 40 45'
Ser He Ser Leu Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser
50 55 60
Thr Asp Leu Asp Val Val Ser Thr He Gin A_sn Val Trp Asp Lys Ser 65 70 75 " 80 Glu Asn Arg Leu Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala
85 90 95
Leu Trp Ala Ser Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val
100 105 110
He Ser Ser Gly Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe 115 120 125
Thr Tyr Arg Tyr Leu Leu Phe Lys Pro Asp Arg Gin Glu Leu Ser Lys
130 135 140
He Val Lys Lys Ser Val Ala Asp He Leu Gly Thr Val Asn Leu Val 145 150 155 160 Cys Val He He Leu His Leu Trp Lys Met He Cys Leu Gin Val Cys
165 170 175
Lys He Thr
(2) INFORMATION FOR SEQ ID NO: 303: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 127 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..127
(D) OTHER INFORMATION: / Ceres Seq. ID 1573863 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:303:
Met Val Lys Ala Ser Gly Glu Ser Ser Asp Ser Ser Thr Asp Leu Asp 1 5 10 15
Val Val Ser Thr He Gin Asn Val Trp Asp Lys Ser Glu Asn Arg Leu 20 25 30 Gly Leu He Gly Leu Gly Phe Ala Gly He Val Ala Leu Trp Ala Ser 35 40 45
Leu Asn Leu He Thr Ala He Asp Lys Leu Pro Val He Ser Ser Gly
50 55 60
Phe Glu Leu Val Gly He Leu Phe Ser Thr Trp Phe Thr Tyr Arg Tyr 65 70 75 80
Leu Leu Phe Lys Pro Asp A.rg Gin Glu Leu Ser Lys He Val Lys Lys 85 90 95 Ser Val Ala Asp He Leu Gly Thr Val Asn Leu Val Cys Val He He
100 105 110
Leu His Leu Trp Lys Met He Cys Leu Gin Val Cys Lys He Thr 115 120 125 (2) INFORMATION FOR SEQ ID NO: 304: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 662 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..662 (D) OTHER INFORMATION: / Ceres Seq. ID 1574093
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 304: attttttctt tctctctctc ctr-cctaagc aaaactaaaa caagctatgg ctggtatgct 60 tcccggagtt gagtgtgcaa ggaggcggcg cttccacggt ggtgctcctc cgattgaatc 120 ctcgaacaca gcttctgtgg cggctgcggc gggacacgtc tggacacggc gaccatcgtt 180 ctctctttac actaccaatc atgagagcca ccaggcccat gtctccttct cggagagaag 240 tgttaggaat aaatcttatg gagaagacaa cgatgagaaa cttgacggag cagccaaaga 300 ggcaaagcag aggcttaaca agcggctαag aatcccacca cgtacaagtt caggcaaaat 360 ggtaaagaca aagggaataa attggagcaa ggaaagggta aacctctcgg ggacttaccg 420 accgaggtgg Gtcgggttaa agaagagccg aggaaggttg atggaatggt tcaagcggcg 480 agttagggaa caacaagatt gtgctatatg tctagaccgg ttcaagaagg gtgagacctt 540 ggtacaccta ccatgtgccc ataagtttca ctccatatgc ttattgcctt ggctagacac 600 taatgtttat tgcccatatt gtagaactga tatttggaat taaatgttat atttttgatg 660 tc (2) INFORMATION FOR SEQ ID NO: 305: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 198 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..198
(D) OTHER INFORMATION: / Ceres Seq. ID 1574094 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 305:
Met Ala Gly Met Leu Pro Gly Val Glu Cys Ala Arg Arg Arg Arg Phe 1 5 10 15
His Gly Gly Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala 20 25 30 Ala Ala Ala Gly His Val Trp Thr Arg Arg Pro Ser Phe Ser Leu Tyr 35 40 45
Thr Thr Asn His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg
50 55 60
Ser Val Arg Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp 65 70 75 80
Gly Ala Ala Lys Glu Ala Lys Gin A.rg Leu Asn Lys Arg Leu Arg He
85 90 95
Pro Pro Arg Thr Ser Ser Gly Lys Met Val Lys Thr Lys Gly He Asn 100 105 110 Trp Ser Lys Glu Arg Val Asn Leu Ser Gly Thr Tyr Arg Pro Arg Trp 115 120 125
Val Gly Leu Lys Lys Ser Arg Gly Arg Leu Met Glu Trp Phe Lys Arg
130 135 140
Arσ Val Arg Glu Gin Gin Asp Cys Ala He Cys Leu Asp Arg Phe Lys 145 150 155 160
Lys Gly Glu Thr Leu Val His Leu Pro Cys Ala His Lys Phe His Ser 165 170 175 He Cys Leu Leu Pro Trp Leu Asp Thr Asn Val Tyr Cys Pro Tyr Cys
180 185 190
Arg Thr Asp He Trp Asn 195
(2) INFORMATION FOR SEQ ID NO: 306: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 195 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..195
(D) OTHER INFORMATION: / Ceres Seq. ID 1574095 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 306: Met Leu Pro Gly Val Glu Cys Ala Arg A.rg Arg Arg Phe His Gly Gly
10 15
Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala Ala Ala Ala
20 25 30
Gly His Val Trp Thr Arg Arg Pro Ser Phe Ser jeu Tyr Thr Thr Asn 35 40 45
His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg Ser Val Arg 50 55 60
Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp Gly Ala Ala
65 70 75 80
Lys Glu Ala Lys Gin Arg Leu Asn Lys Arg Leu A_rg He Pro Pro Arg 85 90 95
Thr Ser S Seerr GGllyy Lys Met Val Lys Thr Lys Gly He Asn Trp Ser Lys 100 105 110
Glu Arg Val Asn Leu Ser Gly Thr Tyr Arg Pro Arg Trp Val Gly Leu
115 120 125
Lys Lys Ser A_rg Gly Arg Leu Met Glu Trp Phe Lys Arg Arg Val Arg
130 135 140
Glu Gin Gin Asp Cys Ala He Cys Leu Asp Arg Phe Lys Lys Gly Glu 145 150 155 160
Thr Leu Val His Leu Pro Cys Ala His Lys Phe His Ser He Cys Leu
165 170 175 Leu Pro Trp Leu Asp Thr Asn Val Tyr Cys Pro Tyr Cys Arg Thr Asp
180 185 190 He Trp Asn 195 (2) INFORMATION FOR SEQ ID NO: 307: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 725 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..725
(D) OTHER INFORMATION: / Ceres Seq. ID 1580388 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 307: ctcacacaaa aatacaacaa cttagatcag tctcaaaggg ggaaaaaaaa cttaaaagaa 60 acattaagag gcaacacaaa tcacacaaaa gatcaaattg aagcctaaga agaaggcaaa 120 aagtgagaag caatggctac catgttgaag gtctctcttg tattgtcatt gttaggtttt 180 ctggtgatcg ctgtcgtgac tccatcggcg gcgaacccat tcaggaagag cgtagttctc 240 ggagggaagt caggcgttcc aaacattcgg accaacaggg aaattcaaca acttggaagg 300 tactgcgtgg agcaattcaa tcaacaagca cagaacgagc aaggaaacat aggatccatt 360 gcgaaaacag acacggcaat ttcgaatcca ttgcaattta gccgagtagt gtctgctcag 420 aaacaggtcg tcgctggact caaatactat ctaaggattg aagtcactca acccaatggc 480 tctaccagga tgtttgactc tgttgtggtt attcaaccat ggctccattc taagcagttg 540 ctcggtttca ctcctgttgt cagtcctgtc tactaacttt atttcttctt attcgactta 600 aatttccata atatgatcaa gaaaagacta aaaggtgtat gatacaaagc tattaagaat 660 gggttaatag ttggttttca tgatatgttt acgttgttca taaataaaaa caagttgtta 720 ttagg
(2) INFORMATION FOR SEQ ID NO: 308: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 147 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..147
(D) OTHER INFORMATION: / Ceres Seq. ID 1580389 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 308: Met Ala Thr Met Leu Lys Val Ser Leu Val Leu Ser Leu Leu Gly Phe 1 5 10 15 Leu Val He Ala Val Val Thr Pro Ser Ala Ala Asn Pro Phe Arg Lys
20 25 30
Ser Val Val Leu Gly Gly Lys Ser Gly Val Pro Asn He Arg Thr Asn
35 40 45
Arg Glu He Gin Gin Leu Gly Arg Tyr Cys Val Glu Gin Phe Asn Gin 50 55 " 60
Gin Ala Gin Asn Glu Gin Gly Asn He Gly Ser He Ala Lys Thr Asp 65 70 75 80
Thr Ala He Ser Asn Pro Leu Gin Phe Ser Arg Val Val Ser Ala Gin 85 90 95 Lys Gin Val Val Ala Gly Leu Lys Tyr Tyr Leu Arg He Glu Val Thr
100 105 110
Gin Pro Asn Gly Ser Thr Arg Met Phe Asp Ser Val Val Val He Gin
115 120 125
Pro Trp Leu His Ser Lys Gin Leu Leu Gly Phe Thr Pro Val Val Ser 130 135 140
Pro Val Tyr 145
(2) INFORMATION FOR SEQ ID NO: 309: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 144 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..144
(D) OTHER INFORMATION: / Ceres Seq. ID 1580390 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 309: Met Leu Lys Val Ser Leu Val Leu Ser Leu Leu Gly Phe Leu Val He 1 5 10 15
Ala Val Val Thr Pro Ser Ala Ala Asn Pro Phe Arg Lys Ser Val Val
20 25 30
Leu Gly Gly Lys Ser Gly Val Pro Asn He Arg Thr Asn Arg Glu He 35 40 45
Gin Gin Leu Gly Arg Tyr Cys Val Glu Gin Phe Asn Gin Gin Ala Gin
50 55 60
Asn Glu Gin Gly Asn He Gly Ser He Ala Lys Thr Asp Thr Ala He 65 70 75 80 Ser Asn Pro Leu Gin Phe Ser Arg Val Val Ser Ala Gin Lys Gin Val
85 90 95
Val Ala Gly Leu Lys Tyr Tyr Leu Arg He Glu Val Thr Gin Pro Asn 100 105 110
Gly Ser Thr Arg Met Phe Asp Ser Val Val Val He Gin Pro Trp Leu
115 120 125
His Ser Lys Gin Leu Leu Gly Phe Thr Pro Val Val Ser Pro Val Tyr 130 135 140
(2) INFORMATION FOR SEQ ID NO: 310: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 675 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..675
(D) OTHER INFORMATION: / Ceres Seq. ID 1582959 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:310: tgggcaaggc aacaaacata atcaacttaa atcttatcta ctttctattt ctttttaatc 60 aaaattaccg ttcttaacta tggcgaagtg gtttttcact atcttcttgg tttttgccct 120 agcctcagct ttagcttgtg gcgcaagaaa cgtcccagta ggcctctctg accaaaagaa 180 ctacctcgga tatggtggcg gatattccgg cgttggagac aatggtttac cctttggtgg 240 cgtcggtgga ggtgtgtctg gtcccggagg taatcttggt tatgggggat ttggtggtgc 300 tggtggcggc ttaggcggtg gtttgggcgg tggagcaggc agtggattag gcggtggctt 360 aggtggtgga agtggaattg gtgccggaac cagtggagga agtaccggag gagttcattt 420 cccttgagtt gttactttgg tttttaaggc gtcatacggt ccttattaag ctaggtctag 480 cttaagatga tgtcataata ataatttatc atatctcttt agggttttaa actttggtat 540 tatgaattat cattagctgt ttaacgtgcg tcttaagtta ctattttaac gtatgtttga 600 atcagtctag tggcttgtcg tgtcatggct tggtccattt tcaaattcta ctttgacctt 660 ttcgagtgtt tcacc (2) INFORMATION FOR SEQ ID NO: 311: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..115 (D) OTHER INFORMATION: / Ceres Seq. ID 1582960
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 311: Met Ala Lys Trp Phe Phe Thr He Phe Leu Val Phe Ala Leu Ala Ser 1 5 10 15
Ala Leu Ala Cys Gly Ala Arg Asn Val Pro Val Gly Leu Ser Asp Gin 20 25 30
Lys Asn Tyr Leu Gly Tyr Gly Gly Gly Tyr Ser Gly Val Gly Asp Asn
35 40 45
Gly Leu Pro Phe Gly Gly Val Gly Gly Gly Val Ser Gly Pro Gly Gly 50 55 60 Asn Leu Gly Tyr Gly Gly Phe Gly Gly Ala Gly Gly Gly Leu Gly Gly 65 70 75 80
Gly Leu Gly Gly Gly Ala Gly Ser Gly Leu Gly Gly Gly Leu Gly Gly
85 90 95
Gly Ser Gly He Gly Ala Gly Thr Ser Gly Gly Ser Thr Gly Gly Val 100 105 110
His Phe Pro 115 (2) INFORMATION FOR SEQ ID NO: 312: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1076 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..1076
(D) OTHER INFORMATION: / Ceres Seq. ID 1663221 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 312: aacacgagct taccgattct cttcgtctca acatttaggg tttcagagat cggctgattt 60 tcacatccac aagtatggcg actcaaatca gcaagaagag aaagtttgta gcggatggtg 120 tattctacgc tgaattgaat gaggttctca caagagagct agcagaggat ggttactctg 180 gtgttgaggt tagggttact ccaatgagga ctgagattat catcagagct actcgtactc 240 agaatgttct tggtgagaag gggaggagaa ttagggaatt gacatctctt gtccagaaga 300 gattcaagtt tccagttgac agtgttgagc tctatgctga gaaggttaac aacagaggtc 360 tctgtgccat tgctcaggct gagtctctac gttacaagct tctcggtggt cttgctgttc 420 gcagggcctg ttatggtgtt ttgagatttg ttatggagag tggagctaag ggatgtgagg 480 tcatcgtgag tggaaagctc cgtgctgcac gtgctaagtc catgaagttc aaggatggtt 540 acatggtttc atctggtcaa ccaactaagg aatacatcga tgctgcagtg agacatgttt 600 tgctcagaca gggggtgttg ggaatcaagg tgaagatcat gcttgactgg gaccctacgg 660 gcaaatcagg accaaagaca ccattgcctg atgttgtgat cattcatgct cctaaagatg 720 atgttgtcta ctctgcacct gctcaggctg ctgctccagt tactcttgtg caagaagctc 780 cactcacaac cgtagattac cctgagatga ttcctccagt ggcctagaga agaccttttt 840 tactattact ccatgggatt ttgttctttt tgttataact tttctacttt tgacactctc 900 tagtcgtatc tcttatatcc tccaagcaga caagtttttt ctcatgttgt ttcttaacct 960 atgtcaagtt ttctggaggt tgaatgcttt tagttccatg atttttttgt tcttaagact 1020 cgtaataaga aaaagaatga cgacaacaat gcctggtatt tgatgttgtt actttg (2) INFORMATION FOR SEQ ID NO:313: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 250 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..250
(D) OTHER INFORMATION: / Ceres Seq. ID 1663222 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 313: Met Ala Thr Gin He Ser Lys Lys Arg Lys Phe Val Ala Asp Gly Val 1 5 10 15 Phe Tyr Ala Glu Leu Asn Glu Val Leu Thr Arg Glu Leu Ala Glu Asp
20 25 30
Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He
35 40 45
He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg 50 55 60
Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys A.rg Phe Lys Phe Pro 65 70 75 80
Val Asp Ser Val Glu Leu Tyr Ala Glu Lys Val Asn Asn Arg Gly Leu 85 90 95 Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly
100 105 110
Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu
115 120 125
Ser Gly Ala Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala 130 135 140
Ala Arg Ala Lys Ser Met Lys Phe Lys Asp Gly Tyr Met Val Ser Ser
145 150 155 160
Gly Gin Pro Thr Lys Glu Tyr He Asp Ala Ala Val Arg His Val Leu
165 170 175 Leu Arg Gin Gly Val Leu Gly He Lys Val Lys He Met Leu Asp Trp
180 185 190
Asp Pro Thr Gly Lys Ser Gly Pro Lys Thr Pro Leu Pro Asp Val Val 195 200 205
He He His Ala Pro Lys Asp Asp Val Val Tyr Ser Ala Pro Ala Gin
210 215 220
Ala Ala Ala Pro Val Thr Leu Val Gin Glu Ala Pro Leu Thr Thr Val 225 230 235 240
Asp Tyr Pro Glu Met He Pro Pro Val Ala 245 250
(2) INFORMATION FOR SEQ ID NO: 314: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 207 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..207
(D) OTHER INFORMATION: / Ceres Seq. ID 1663223 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:314: Met Arg Thr Glu He He He Arg Ala Thr Arg Thr Gin Asn Val Leu 1 5 10 15
Gly Glu Lys Gly Arg Arg He Arg Glu Leu Thr Ser Leu Val Gin Lys
20 25 30
Arg Phe Lys Phe Pro Val Asp Ser Val Glu Leu Tyr Ala Glu Lys Val 35 40 45
Asn Asn Arg Gly Leu Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr
50 55 60
Lys Leu Leu Gly Gly Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu 65 70 75 80 Arg Phe Val Met Glu Ser Gly Ala Lys Gly Cys Glu Val He Val Ser
85 90 95
Gly Lys Leu Arg Ala Ala Arg Ala Lys Ser Met Lys Phe Lys Asp Gly
100 105 110
Tyr Met Val Ser Ser Gly Gin Pro Thr Lys Glu Tyr He Asp Ala Ala 115 120 125
Val Arg His Val Leu Leu Arg Gin Gly Val Leu Gly He Lys Val Lvs
130 135 140
He Met Leu Asp Trp Asp Pro Thr Gly Lys Ser Gly Pro Lys Thr Pro 145 150 155 160 Leu Pro Asp Val Val He He His Ala Pro Lys Asp Asp Val Val Tyr
165 170 175 Ser Ala Pro Ala Gin Ala Ala Ala Pro Val Thr Leu Val Gin Glu Ala 180 185 190
Pro Leu Thr Thr Val Asp Tyr Pro Glu Met He Pro Pro Val Ala 195 200 205
(2) INFORMATION FOR SEQ ID NO: 315: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 488 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..488
(D) OTHER INFORMATION: / Ceres Seq. ID 1663275 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 315: gtgactaaat ttctagggtt ttgaagagtc tctctcgtcg ccgtttgtta ttcctctgtg 60 agcaaatcga cgaaatgggt cactctaatg tatggaactc tcatccgaag aagtacggtc 120 ctggatctcg tttatgccgt gtgtgcggga actcgcacgg tctgatccgg aagtatggtt 180 tgaactgctg cagacagtgt ttccgtagca acgctaagga gattggattc attaagtacc 240 gttaatcaag caccaacttc atgattgatg cttaatgata taaacatgaa ggcgtcgatg 300 ggtatggctt ttaagctttt gtagtttttg aaatttttac ttttgagaac cattgttatt 360 ttgggagtta attaagttgt tgaacctcat taagcatgtc ttattttgga ttaatgatgt 420 tttggctatt ctcgtatttt tgttttatca gtcaaatttg actaagaaga atttgcttgt 480 tattagcc
(2) INFORMATION FOR SEQ ID NO: 316:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 56 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..56
(D) OTHER INFORMATION: / Ceres Seq. ID 1663276
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:316:
Met Gly His Ser Asn Val Trp Asn Ser His Pro Lys Lys Tyr Gly Pro
1 5 10 15
Gly Ser Arg Leu Cys Arg Val Cys Gly Asn Ser His Gly Leu He Arg
20 25 30
Lys Tyr Gly Leu Asn Cys Cys Arg Gin Cys Phe Arg Ser Asn Ala Lys
35 40 45
Glu He Gly Phe He Lys Tyr Arg
50 55
(2) INFORMATION FOR SEQ ID NO: 317:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 38 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..38
(D) OTHER INFORMATION: / Ceres Seq. ID 1663277 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 317:
Met Glu Leu Ser Ser Glu Glu Val Arg Ser Trp He Ser Phe Met Pro
1 5 10 15
Cys Val Arg Glu Leu Ala Arg Ser Asp Pro Glu Val Trp Phe Glu Leu
20 25 30
Leu Gin Thr Val Phe Pro 35
(2) INFORMATION FOR SEQ ID NO:318: (i SEQUENCE CHARACTERISTICS:
(A) LENGTH: 759 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY: -
(B) LOCATION: 1..759 (D) OTHER INFORMATION: / Ceres Seq. ID 1665304
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 318: atcaaccaaa acaaaacata aaaaacaagt ggaagcttta aaacgagagg gagagagcaa 60 aaatggcgac gtcgggaacg tacgtgacgg aagttccgct aaaaggatcg gccgagaaat 120 actacaagag gtggaagaac gagaaccatg tcttccctga tgctatcggc caccacatcc 180 aaaatgttac cgttcacgaa ggcgaacatg actctcacgg gtctatcagg agttggaact 240 acacatggga tggaaaggag gaggtgttca aggagagaag agagatagac gatgagacca 300 aaacgttgac gttaagagga cttgagggtc acgtgatgga gcagctcaaa gtgtacgacg 360 tcgtctacca attcattccc aaatctgagg atacctgcat cggcaaaatc actttaatat 420 gggagaagcg caacgatgat tccccagaac caagcggcta catgaaattc gtcaagagct 480 tggttgctga catgggaaac cacgttagca aaacttaatc atcattccca cagtcgtcgt 540 cgtcgtcatc atcatcatca tcatcatcat catcatcatc atcatcatca tcatcatcat 600 catcactatc tcgatttata agttaagatg ttttcagtat aataaatggg gtcttgtgga 660 tcgttcattt ctatgtgtaa accgtttggt tctgtatgat gcttcgatat attgttatgt 720 tcatgatcat atgtcgggtt cgatataatg attcttaag (2) INFORMATION FOR SEQ ID NO: 319: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 151 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..151
(D) OTHER INFORMATION: / Ceres Seq. ID 1665305 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 319: Met Ala Thr Ser Gly Thr Tyr Val Thr Glu Val Pro Leu Lys Gly Ser 1 5 10 15 Ala Glu Lys Tyr Tyr Lys Arg Trp Lys Asn Glu Asn His Val Phe Pro
20 25 30
Asp Ala He Gly His His He Gin Asn Val Thr Val His Glu Gly Glu
35 " 40 45
His Asp Ser His Gly Ser He Arg Ser Trp Asn Tyr Thr Trp Asp Gly 50 55 60
Lys Glu Glu Val Phe Lys Glu Arg Arg Glu He Asp Asp Glu Thr Lys 65 70 75 80
Thr Leu Thr Leu Arg Gly Leu Glu Gly His Val Met Glu Gin Leu Lys 85 90 95 Val Tyr Asp Val Val Tyr Gin Phe He Pro Lys Ser Glu Asp Thr Cys
100 105 110
He Gly Lys He Thr Leu He Trp Glu Lys Arg Asn Asp Asp Ser Pro
115 120 125
Glu Pro Ser Gly Tyr Met Lys Phe Val Lys Ser Leu Val Ala Asp Met 130 135 140
Gly Asn His Val Ser Lys Thr 145 150
(2) INFORMATION FOR SEQ ID NO: 320: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 602 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..602
(D) OTHER INFORMATION: / Ceres Seq. ID 1709970 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 320: gaagtctctt atatataagt atcgagagaa ttagggtttt ctagtctagt gtttccggga 60 gcagcctgag caggaggaag aagacgaaga agaagaggag cagctactac catggttctg 120 ggacggagct ttgtcgtttc agtggacaga agatttaccc aggaagagga attaggttta 180 tccgatctga ttctcaggtt ttcttgtttc ttaactcaaa atgtaagagg tacttccata 240 acaagttgaa gccatccaag cttgcatgga ctgccatgta cagaaagcaa cncaagaagg 300 atgcagcaca agaggctgtg aagagaagga gacgtgccac caagaagcca tactcaaggt 360 ccattgttgg tgctaccttg gaagtaattc agaagaagag agctgagaag cctgaagttc 420 gtgatgcagc cagggaagct gctctgcgtg agatcaagga aagaatcaaa aagaccaaag 480 atgaaaagaa ggctaagaag gtggaatttg cttctaagca acagaaggtc aaggctaatt 540 tccccaaagc tgctgctgca tccaagggtc ctaaggtggg aggtggtggt ggcaaacgct 600 ga
(2) INFORMATION FOR SEQ ID NO: 321: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 108 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..108
(D) OTHER INFORMATION: / Ceres Seq. ID 1709971 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:321: Met Tyr Arg Lys Gin Xaa Lys Lys Asp Ala Ala Gin Glu Ala Val Lys 1 " 5 10 15
Arg A.rg Arg Arg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly
20 25 30
Ala Thr Leu Glu Val He Gin Lys Lys Arg Ala Glu Lys Pro Glu Val
35 40 45
Arg Asp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu Arg He
50 55 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Val Glu Phe Ala Ser 65 ' 70 75 80
Lys Gin Gin Lys Val Lys Ala Asn Phe Pro Lys Ala Ala Ala Ala Ser
85 90 95
Lys Gly Pro Lys Val Gly Gly Gly Gly Gly Lys Arg
100 105
(2) INFORMATION FOR SEQ ID NO: 322: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 1709972 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 322:
Met G Pro Gly Lys Leu Leu Cys Val Arg Ser A g Lys Glu Ser Lys
1 " 5" 10 15
Arg Pro Lys Met Lys Arg Arg Leu Arg Arg Trp Asn Leu Leu Leu Ser
20 25 30
Asn Arg Arg Ser Arg Leu He Ser Pro Lys Leu Leu Leu His Pro Arg
35 40 45
Val Leu Arg Trp Glu Val Val Val Ala Asn Ala
50 55
(2) INFORMATION FOR SEQ ID NO: 323: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 726 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..726
(D) OTHER INFORMATION: / Ceres Seq. ID 1711273 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:323: atcttcttgt ctctctctca tttcttgtta ttatccacga acgaagaaaa acctagaaaa 60 cagttgaaga aagaaaatca caagagaagc catggccgga attggaccga ttactcagga 120 ttgggaacca gttgtgatcc gcaagagagc tcctaacgct gcagctaagc gcgacgagaa 180 gactgtcaac gccgctcgtc gaagcggcgc cgatattgag accgttcgaa aattcaatgc 240 tggatcgaac aaggctgcat caagcggcac ctccttgaac acaaagaagc tagatgatga 300 tactgagaac ttatctcatg atcgtgtgcc cactgaattg aagaaagcca tcatgcaagc 360 tagaggggag aasaagctga ctcagtccca acttgcccat ctgatcaatg agaagccaca 420 agtgatccaa gaatacgagt cggggaaagc aattccgaat caacagatcc tttcaaagct 480 ggagagggca cttggtgcta aactccgtgg aaagaagtag aagtttagaa caaagctctt 540 aaaggtaaca aaaagctgat cgcagtttct ctccagtcca catgctttac catatcctaa 600 aaactatatc tatgtatggt ttggtttaat ggcgtagtag tttgttgcga ggaatctttc 660 atgatgtaag aaaaacaaag ctgtttggaa ccttttgtca ttataaataa tctcttctct 720 ttcttt (2) INFORMATION FOR SEQ ID NO: 324:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 142 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide (IX) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..142
(D) OTHER INFORMATION: / Ceres Seq. ID 1711274
(XI) SEQUENCE DESCRIPTION: SEQ ID NO: 324:
Met Ala Gly He Gly Pro He Thr Gin Asp Trp Glu Pro Val Val He
10 15
Arg Lys Arg Ala Pro Asn Ala Ala Ala Lys Arg Asp Glu Lvs Thr Val
20 25 " 30
Asn Ala Ala Arg Arg Ser Gly Ala Asp He Glu Thr Val Arg Lys Phe
35 40 45
Asn Ala Gly Ser Asn Lys Ala Ala Ser Ser Gly Thr Ser Leu Asn Thr
50 55 60
Lys Lys Leu Asp Asp Asp Thr Glu Asn Leu Ser His Asp Arg Val Pro 65 70 75 80
Thr Glu Leu Lys Lys Ala He Met Gin Ala Arg Gly Glu Xaa Lys Leu
85 90 95
Thr Gin Ser Gin Leu Ala His Leu He Asn Glu Lys Pro Gin Val He 100 105 110
Gin Glu Tyr Glu Ser Gly Lys Ala He Pro Asn Gin Gin He Leu Ser
115 120 125
Lys Leu Glu Arg Ala Leu Gly Ala Lys Leu Arg Gly Lys Lys
130 135 140
(2) INFORMATION FOR SEQ ID NO: 325: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 686 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..686
(D) OTHER INFORMATION: / Ceres Seq. ID 1715423 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 325: aacaataaaa caaagtgatt tattatggcg ttaagagaga tgataataga tgagagtgat 60 gacatagaga gctacagtga tcaatctctt tgtcttgata aagccaagga gcttcttgct 120 ctcatcaaac tacccacggg attgttgcca ttgaaggata tgacggaagt tgggtacaac 180 aaaacaaaag ggtttgtgtg gatgaggctg agaagcaaga ttgagcatac attccgtgag 240 ataggtcgca gagttttata tgacacggYa gataactgcg tttgttgagg accgccgtat 300 gaggagactt accggagtca aaagcaaaga gctcatgatc tgggttcctg tgaatgatat 360 cttcatcaaa gagaaagatc ctgagaagat cacctttgct aataccaccg gcctgtcacg 420 aacatttaaa gtttcagcat ttcaatgtga aggttgataa ataaaaagaa aagaggagta 480 accagacttc cttgatgaaa gcaaccaata aagaacagaa gttgttccat actcaataag 540 agatagttta attaaatatc aaggacacgc ctttcttaca atgaattgct tatggatcat 600 cacagtaaat aaacaggttc tgcaattgat gccttgatgt ataacagtga gtttccaatc 660 aacatattag aatcgattca ttggtt (2) INFORMATION FOR SEQ ID NO: 326: (ι) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 87 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide ( x) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..87 (D) OTHER INFORMATION: / Ceres Seq. ID 1715424
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:326: Met Ala Leu Arg Glu Met He He Asp Glu Ser Asp Asp He Glu Ser 1 5 10 15
Tyr Ser Asp Gin Ser Leu Cys Leu Asp Lys Ala Lys Glu Leu Leu Ala 20 25 30
Leu He Lys Leu Pro Thr Gly Leu Leu Pro Leu Lys Asp Met Thr Glu
35 40 45
Val Gly Tyr Asn Lys Thr Lys Gly Phe Val Trp Met Arg Leu Arg Ser 50 55 60 Lys He Glu His Thr Phe Arg Glu He Gly Arg Arg Val Leu Tyr Asp 65 70 75 80
Thr Xaa Asp Asn Cys Val Cys
85 (2) INFORMATION FOR SEQ ID NO: 327: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 82 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..82
(D) OTHER INFORMATION: / Ceres Seq. ID 1715425 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 327:
Met He He Asp Glu Ser A_sp Asp He Glu Ser Tyr Ser Asp Gin Ser 1 5 10 15
Leu Cys Leu Asp Lys Ala Lys Glu Leu Leu Ala Leu He Lys Leu Pro 20 25 30 Thr Gly Leu Leu Pro Leu Lys Asp Met Thr Glu Val Gly Tyr Asn Lys 35 40 45
Thr Lys Gly Phe Val Trp Met Arg Leu Arg Ser Lys He Glu His Thr
50 55 60
Phe Arg Glu He Gly Arg Arg Val Leu Tyr Asp Thr Xaa Asp Asn Cys 65 70 75 80
Val Cys
(2) INFORMATION FOR SEQ ID NO: 328: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 65 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1715426 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 328: Met Thr Arg Xaa He Thr Ala Phe Val Glu Asp Arg Arg Met Arg Arg 1 5 10 15
Leu Thr Gly Val Lys Ser Lys Glu Leu Met He Trp Val Pro Val Asn 20 25 30
Asp He Phe He Lys Glu Lys Asp Pro Glu Lys He Thr Phe Ala Asn
35 40 45
Thr Thr Gly Leu Ser Arg Thr Phe Lys Val Ser Ala Phe Gin Cys Glu 50 55 60
Gly 65
(2) INFORMATION FOR SEQ ID NO:329: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 829 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..829
(D) OTHER INFORMATION: / Ceres Seq. ID 1715962 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:329: aaaaacgccg tcgagaaatc tccctctagg gtttctttga tcaaaccaga gagccgtcag 60 ggagagcaaa acaaagatcg gagaagatga agacgattct ttcttccgaa acgatggaca 120 tccccgacag tgttaccatc aaggttcacg ctaaagtgat cgaagtcgaa ggacctcgcg 180 ggaagcttgt tcgcgatttc aagcatctca acctcgattt ccagctgatc aaggatccag 240 agactggaaa gaagaagctt aagatcgatt cgtggtttgg aacacgcaaa accagcgcct 300 ccatcagaac cgctcttagc cacgtcgata acttgatctc cggtgttacc agaggtttcc 360 gttacaagat gaggttcgtg tacgcccatt ttcccatcaa cgcctccatc ggcggtgacg 420 gaaagtctat cgagatccgt aacttccttg gcgagaagaa ggtgaggaag gtagagatgt 480 tggatggtgt aacCattgtt cgaYctgaga aggtgaagga tgagattgtt cttgacggta 540 acgacatcga gcttgtttca aggtcatgcg ctttgatcaa ccagaaatgt cacgtgaaga 600 agaaggatat caggaagttt cttgatggta tctatgttag cgagaaaagc aagatcgtag 660 aggaagaatg aatgcccata tcatcgtctt agctcctatt tcttgtcttt tgaatgttag 720 tttcgtttta tggaccaaat ccaccggtgt tgcaaaactc tggctatccc ttgttccctt 780 tttgtgttcg agattttatt tacttatgca caagttttgg agacgagct (2) INFORMATION FOR SEQ ID NO: 330: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 194 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..194
(D) OTHER INFORMATION: / Ceres Seq. ID 1715963 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 330:
Met Lys Thr He Leu Ser Ser Glu Thr Met Asp He Pro Asp Ser Val 1 5 10 15
Thr He Lys Val His Ala Lys Val He Glu Val Glu Gly Pro Arg Gly 20 " 25 30 Lys Leu Val Arg Asp Phe Lys His Leu Asn Leu Asp Phe Gin Leu He 35 40 45
Lys Asp Pro Glu Thr Gly Lys Lys Lys Leu Lys He Asp Ser Trp Phe
50 55 60
Gly Thr Arg Lys Thr Ser Ala Ser He Arg Thr Ala Leu Ser His Val 65 70 ' 75 80
Asp Asn Leu He Ser Gly Val Thr Arg Gly Phe Arg Tyr Lys Met Arg
85 90 95
Phe Val Tyr Ala His Phe Pro He Asn Ala Ser He Gly Gly Asp Gly 100 105 110 Lys Ser He Glu He Arg Asn Phe Leu Gly Glu Lys Lys Val Arg Lys 115 120 125
Val Glu Met Leu Asp Gly Val Thr He Val Arg Xaa Glu Lys Val Lys 130 135 140
Asp Glu He Val Leu Asp Gly Asn Asp He Glu Leu Val Ser Arg Ser 145 150 155 160
Cys Ala Leu He Asn Gin Lys Cys His Val Lys Lys Lys Asp He Arg 165 170 175
Lys Phe Leu Asp Gly He Tyr Val Ser Glu Lys Ser Lys He Val Glu
180 185 190
Glu Glu (2) INFORMATION FOR SEQ ID NO: 331: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 185 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..185 (D) OTHER INFORMATION: / Ceres Seq. ID 1715964
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 331: Met A.sp He Pro Asp Ser Val Thr He Lys Val His Ala Lys Val He 1 5 10 15
Glu Val Glu Gly Pro A.rg Gly Lys Leu Val Arg Asp Phe Lys His Leu 20 25 30
Asn Leu Asp Phe Gin Leu He Lys Asp Pro Glu Thr Gly Lys Lys Lys
35 40 45
Leu Lys He Asp Ser Trp Phe Gly Thr Arg Lys Thr Ser Ala Ser He 50 55 60 Arg Thr Ala Leu Ser His Val Asp Asn Leu He Ser Gly Val Thr Arg 65 70 75 80
Gly Phe Arg Tyr Lys Met Arg Phe Val Tyr Ala His Phe Pro He Asn
85 90 95
Ala Ser He Gly Gly Asp Gly Lys Ser He Glu He Arg Asn Phe Leu 100 105 110
Gly Glu Lys Lys Val Arg Lys Val Glu Met Leu Asp Gly Val Thr He
115 120 125
Val A.rg Xaa Glu Lys Val Lys Asp Glu He Val Leu Asp Gly Asn Asp
130 135 140 He Glu Leu Val Ser Arg Ser Cys Ala Leu He Asn Gin Lys Cys His
145 150 155 160
Val Lys Lys Lys Asp He Arg Lys Phe Leu Asp Gly He Tyr Val Ser
165 170 175
Glu Lys Ser Lys He Val Glu Glu Glu 180 185
(2) INFORMATION FOR SEQ ID NO: 332: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 100 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..100
(D) OTHER INFORMATION: / Ceres Seq. ID 1715965 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 332: Met Arg Phe Val Tyr Ala His Phe Pro He Asn Ala Ser He Gly Gly 1 5 10 15 Asp Gly Lys Ser He Glu He Arg Asn Phe Leu Gly Glu Lys Lys Val 20 25 30
Arg Lys Val Glu Met Leu Asp Gly Val Thr He Val Arg Xaa Glu Lys 35 40 45
Val Lys Asp Glu He Val Leu Asp Gly Asn Asp He Glu Leu Val Ser
50 55 60
Arg Ser Cys Ala Leu He Asn Gin Lys Cys His Val Lys Lys Lys Asp 65 70 75 80
He Arg Lys Phe Leu Asp Gly He Tyr Val Ser Glu Lys Ser Lys He
85 ~ 90 95
Val Glu Glu Glu 100 (2) INFORMATION FOR SEQ ID NO: 333: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 675 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..675 (D) OTHER INFORMATION: / Ceres Seq. ID 1808584
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 333: aacttgtcac ctgcagagaa agaaagaagc cctagatttt gtcaaaaggc ggttgcagaa 60 caaaaaacca tggccggaat tggaccgata actcaggatt gggagccggt ggtgatccgt 120 aagaaacccg ctaacgccgc tgccaagcgc gacgagaaaa ctgtcaacgc cgctcgtcga 180 tccggcgccg atatcgagac cgtcagaaaa ttcaatgctg gaaccaacaa ggcggcatca 240 agcggcacat ctctgaacac aaaaatgctt gatgatgaca ctgagaacct tactcatgaa 300 cgtgtgccta ctgagctaaa gaaagccatt atgcaagcca ggacagacaa gaagctaacc 360 cagtcccaac ttgctcaaat catcaatgag aagccacaag tgattcaaga gtatgagtct 420 ggcaaagcta tacccaacca gcaaatcctt tctaagctgg agagagcgct tggagctaag 480 cttcgtggaa agaagtgagc caagttctac tgatgtagca agtaacaaga atcaatgctt 540 tcgtctaatg ccgtaacttt gccaagaaga atattttctg attgtaagaa agcaaaaccg 600 tttgaatgtt tgtttcgttg atggaatctc tatctcataa actcatatca atataataac 660 ttgggtcttt tcatc (2) INFORMATION FOR SEQ ID NO: 334: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 165 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..165
(D) OTHER INFORMATION: / Ceres Seq. ID 1808585 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:334:
Asn Leu Ser Pro Ala Glu Lys Glu Arg Ser Pro Arg Phe Cys Gin Lys 1 5 10 15
Ala Val Ala Glu Gin Lys Thr Met Ala Gly He Gly Pro He Thr Gin 20 25 30 Asp Trp Glu Pro Val Val He Arg Lys Lys Pro Ala Asn Ala Ala Ala 35 40 45
Lys Arg Asp Glu Lys Thr Val Asn Ala Ala Arg A.rg Ser Gly Ala Asp
50 55 60
He Glu Thr Val Arg Lys Phe Asn Ala Gly Thr Asn Lys Ala Ala Ser 65 70 75 80
Ser Gly Thr Ser Leu Asn Thr Lys Met Leu Asp A.sp Asp Thr Glu Asn
85 90 95
Leu Thr His Glu Arg Val Pro Thr Glu Leu Lys Lys Ala He Met Gin 100 105 110 Ala Arg Thr Asp Lys Lys Leu Thr Gin Ser Gin Leu Ala Gin He He 115 120 125
Asn Glu Lys Pro Gin Val He Gin Glu Tyr Glu Ser Gly Lys Ala He 130 135 140
Pro Asn Gin Gin He Leu Ser Lys Leu Glu Arg Ala Leu Gly Ala Lys 145 150 155 160
Leu Arg Gly Lys Lys 165
(2) INFORMATION FOR SEQ ID NO: 335: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 142 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..142
(D) OTHER INFORMATION: / Ceres Seq. ID 1808586 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 335: Met Ala Gly He Gly Pro He Thr Gin Asp Trp Glu Pro Val Val He 1 5 10 15 Arg Lys Lys Pro Ala Asn Ala Ala Ala Lys Arg Asp Glu Lys Thr Val
20 25 30
Asn Ala Ala Arg Arg Ser Gly Ala Asp He Glu Thr Val Arg Lys Phe
35 40 45
Asn Ala Gly Thr Asn Lys Ala Ala Ser Ser Gly Thr Ser Leu Asn Thr 50 55 60
Lys Met Leu Asp Asp Asp Thr Glu Asn Leu Thr His Glu Arg Val Pro 65 70 75 80
Thr Glu Leu Lys Lys Ala He Met Gin Ala Arg Thr Asp Lys Lys Leu 85 90 95 Thr Gin Ser Gin Leu Ala Gin He He Asn Glu Lys Pro Gin Val He
100 105 110
Gin Glu Tyr Glu Ser Gly Lys Ala He Pro Asn Gin Gin He Leu Ser
115 120 125
Lys Leu Glu Arg Ala Leu Gly Ala Lys Leu Arg Gly Lys Lys 130 135 140
(2) INFORMATION FOR SEQ ID NO: 336: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 630 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..630
(D) OTHER INFORMATION: / Ceres Seq. ID 1808591 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:336: aacactacaa caattttcat acctcatatt ctcttccatg gcaaccacca agcacctcct 60 cctcttcctc ctcatcatcg ctatcatcac cattacatct tccacttcac ttccatttct 120 cacgacggag caaaaccaaa tcgcaaccaa aatcatagac gcaatggtct caagtggctc 180 tttcgaagat tggagcggag cgttcctcaa caacaacgac gaattaaacg gtccagtcct 240 aacttcaact ctcttcctcc ccaaaacatc cgtggaagga atcaacgcca cgtcaccact 300 agttgcttct taccatattg ttccacaatg gcttgacttc tccgtcataa gtctcatgat 360 gcctttctct cgcatcccta cactcctctc tggacactct atagtcgtta ccaacaattc 420 agcttctggt tttactcttg atggtgttct catctctgag ccagatttat tcgtctctcc 480 tactatagtt atccatcgaa tggcttttcc atttaacttc tctcgttacg gtggtggcga 540 tatatagtta tttacttttg attcgcttct ccactttgtt tctttctact tttactaata 600 cactttcaaa taattaacaa cgaacttgac (2) INFORMATION FOR SEQ ID NO: 337: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 181 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..181
(D) OTHER INFORMATION: / Ceres Seq. ID 1808592 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 337: Thr Leu Gin Gin Phe Ser Tyr Leu He Phe Ser Ser Met Ala Thr Thr 1 5 10 15
Lys His Leu Leu Leu Phe Leu Leu He He Ala He He Thr He Thr
20 25 30
Ser Ser Thr Ser Leu Pro Phe Leu Thr Thr Glu Gin Asn Gin He Ala 35 40 45 Thr Lys He He Asp Ala Met Val Ser Ser Gly Ser Phe Glu Asp Trp 50 55 60
Ser Gly Ala Phe Leu Asn Asn Asn Asp Glu Leu Asn Gly Pro Val Leu 65 70 75 80
Thr Ser Thr Leu Phe Leu Pro Lys Thr Ser Val Glu Gly He Asn Ala 85 90 95
Thr Ser Pro Leu Val Ala Ser Tyr His He Val Pro Gin Trp Leu Asp
100 105 110
Phe Ser Val He Ser Leu Met Met Pro Phe Ser Arg He Pro Thr Leu 115 120 125 Leu Ser Gly His Ser He Val Val Thr Asn Asn Ser Ala Ser Gly Phe 130 135 140
Thr Leu Asp Gly Val Leu He Ser Glu Pro Asp Leu Phe Val Ser Pro 145 150 155 160
Thr He Val He His Arg Met Ala Phe Pro Phe Asn Phe Ser Arg Tyr 165 170 175
Gly Gly Gly Asp He
180 (2) INFORMATION FOR SEQ ID NO- 338: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 169 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..169
(D) OTHER INFORMATION: / Ceres Seq. ID 1808593 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 338: Met Ala Thr Thr Lys His Leu Leu Leu Phe Leu Leu He He Ala He 1 5 10 15
He Thr He Thr Ser Ser Thr Ser Leu Pro Phe Leu Thr Thr Glu Gin
20 25 30
Asn Gin He Ala Thr Lys He He Asp Ala Met Val Ser Ser Gly Ser 35 40 45
Phe Glu Asp Trp Ser Gly Ala Phe Leu Asn Asn Asn Asp Glu Leu Asn
50 55 60
Gly Pro Val Leu Thr Ser Thr Leu Phe Leu Pro Lys Thr Ser Val Glu 65 70 75 80 Gly He Asn Ala Thr Ser Pro Leu Val Ala Ser Tyr His He Val Pro
85 90 95
Gin Trp Leu Asp Phe Ser Val He Ser Leu Met Met Pro Phe Ser Arg
100 105 110
He Pro Thr Leu Leu Ser Gly His Ser He Val Val Thr Asn Asn Ser 115 120 125
Ala Ser Gly Phe Thr Leu Asp Gly Val Leu He Ser Glu Pro Asp Leu 130 135 140 Phe Val Ser Pro Thr He Val He His Arg Met Ala Phe Pro Phe Asn 145 150 155 160
Phe Ser Arg Tyr Gly Gly Gly Asp He
165 (2) INFORMATION FOR SEQ ID NO: 339: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 127 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..127
(D) OTHER INFORMATION: / Ceres Seq. ID 1808594
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 339:
Met Val Ser Ser Gly Ser Phe Glu Asp Trp Ser Gly Ala Phe Leu Asn
1 5 10 15
Asn Asn Asp Glu Leu Asn Gly Pro Val Leu Thr Ser Thr Leu Phe Leu 20 25 30
Pro Lys Thr Ser Val Glu Gly He Asn Ala Thr Ser Pro Leu Val Ala 35 40 45
Ser Tyr His He Val Pro Gin Trp Leu Asp Phe Ser Val He Ser Leu 50 55 60
Met Met Pro Phe Ser Arg He Pro Thr Leu Leu Ser Gly His Ser He
65 70 75 80
Val Val Thr Asn Asn Ser Ala Ser Gly Phe Thr Leu Asp Gly Val Leu 85 90 95
He Ser Glu Pro Asp Leu Phe Val Ser Pro Thr He Val He His Arg 100 105 110
Met Ala Phe Pro Phe Asn Phe Ser Arg Tyr Gly Gly Gly Asp He 115 120 125
(2) INFORMATION FOR SEQ ID NO: 340: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 717 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..717
(D) OTHER INFORMATION: / Ceres Seq. ID 1920563 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:340: cttgtttata ctaatgacca aggagagact gttaaaggag tttgctcaaa tttcttgtgt 60 gatttggcac ccggaagtga tgttaagctg actggtcctg taggcaaaga aatgcttatg 120 cctaaggatc caaacgccac cgtaattatg cttgccacag ggacaggaat tgctcctttc 180 aggtctttct tatggaagat gttctttgag aaacatgatg actacaagtt caatggctta 240 gcttggttgt tcttgggtgt accaaccact agctcattgc tctaccaaga ggagtttgat 300 aagatgaaag caaaggcccc cgagaacttc agggtggatt acgcgataag cagagaacaa 360 gcgaacgata aaggagagaa aatgtatatc cagactcgga tggcacagta cgcagctgaa 420 ttatgggagt tgttgaagaa agacaacact tttgtttaca tgtgtggact caagggaatg 480 gagaaaggaa ttgatgacat tatggtctca ttggctgcaa atgacggtat tgactggttt 540 gattacaaga agcagttgaa gaaggcagag caatggaacg ttgaagtcta ctgatcaaaa 600 agcctttgac atttctgtag caaagtatag ctgaacaaaa ctgtaatttt cgcttccgaa 660 tttctgtatt ttgaagataa gttttttaga tatgttatac taaaaaaaga gttcttt (2) INFORMATION FOR SEQ ID NO: 341: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 197 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ( ii ) MOLECULE TYPE : peptide ( ix ) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..197 (D) OTHER INFORMATION: / Ceres Seq. ID 1920564
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 341: Leu Val Tyr Thr Asn Asp Gin Gly Glu Thr Val Lys Gly Val Cys Ser 1 5 10 15
Asn Phe Leu Cys Asp Leu Ala Pro Gly Ser Asp Val Lys Leu Thr Gly 20 25 30
Pro Val Gly Lys Glu Met Leu Met Pro Lys Asp Pro Asn Ala Thr Val
35 40 45
He Met Leu Ala Thr Gly Thr Gly He Ala Pro Phe Arg Ser Phe Leu 50 55 60 Trp Lys Met Phe Phe Glu Lys His Asp Asp Tyr Lys Phe Asn Gly Leu 65 70 75 80
Ala Trp Leu Phe Leu Gly Val Pro Thr Thr Ser Ser Leu Leu Tyr Gin
85 90 95
Glu Glu Phe Asp Lys Met Lys Ala Lys Ala Pro Glu Asn Phe Arg Val 100 105 110
Asp Tyr Ala He Ser Arg Glu Gin Ala Asn Asp Lys Gly Glu Lys Met
115 120 125
Tyr He Gin Thr Arg Met Ala Gin Tyr Ala Ala Glu Leu Trp Glu Leu
130 135 140 Leu Lys Lys Asp Asn Thr Phe Val Tyr Met Cys Gly Leu Lys Gly Met
145 150 155 160
Glu Lys Gly He Asp Asp He Met Val Ser Leu Ala Ala Asn Asp Gly
165 170 175
He Asp Trp Phe Asp Tyr Lys Lys Gin Leu Lys Lys Ala Glu Gin Trp 180 185 190
Asn Val Glu Val Tyr
195 (2) INFORMATION FOR SEQ ID NO: 342: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 160 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..160
(D) OTHER INFORMATION: / Ceres Seq. ID 1920565 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 342: Met Leu Met Pro Lys Asp Pro Asn Ala Thr Val He Met Leu Ala Thr 1 5 10 15
Gly Thr Gly He Ala Pro Phe Arg Ser Phe Leu Trp Lys Met Phe Phe
20 25 30
Glu Lys His Asp Asp Tyr Lys Phe Asn Gly Leu Ala Trp Leu Phe Leu 35 40 45
Gly Val Pro Thr Thr Ser Ser Leu Leu Tyr Gin Glu Glu Phe Asp Lys
50 55 60
Met Lys Ala Lys Ala Pro Glu Asn Phe Arg Val Asp Tyr Ala He Ser 65 70 75 80 Arg Glu Gin Ala Asn Asp Lys Gly Glu Lys Met Tyr He Gin Thr Arg
85 90 95
Met Ala Gin Tyr Ala Ala Glu Leu Trp Glu Leu Leu Lys Lys Asp Asn
100 105 110
Thr Phe Val Tvr Met Cys Gly Leu Lys Gly Met Glu Lys Gly He Asp 115 ' 120 125
Asp He Met Val Ser Leu Ala Ala Asn Asp Gly He Asp Trp Phe Asp 130 135 140 Tyr Lys Lys Gin Leu Lys Lys Ala Glu Gin Trp Asn Val Glu Val Tyr 145 150 155 160
(2) INFORMATION FOR SEQ ID NO:343: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 158 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..158
(D) OTHER INFORMATION: / Ceres Seq. ID 1920566 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 343: Met Pro Lys Asp Pro Asn Ala Thr Val He Met Leu Ala Thr Gly Thr 1 5 10 15
Gly He Ala Pro Phe Arg Ser Phe Leu Trp Lys Met Phe Phe Glu Lys
20 25 30
His Asp Asp Tyr Lys Phe Asn Gly Leu Ala Trp Leu Phe Leu Gly Val 35 40 45
Pro Thr Thr Ser Ser Leu Leu Tyr Gin Glu Glu Phe Asp Lys Met Lys
50 55 60
Ala Lys Ala Pro Glu Asn Phe Arg Val Asp Tyr Ala He Ser Arg Glu 65 70 75 80 Gin Ala Asn Asp Lys Gly Glu Lys Met Tyr He Gin Thr Arg Met Ala
85 90 95
Gin Tyr Ala Ala Glu Leu Trp Glu Leu Leu Lys Lys Asp Asn Thr Phe
100 105 110
Val Tyr Met Cys Gly Leu Lys Gly Met Glu Lys Gly He Asp Asp He 115 120 125
Met Val Ser Leu Ala Ala Asn Asp Gly He Asp Trp Phe Asp Tyr Lys
Lys Gin Leu Lys Lys Ala Glu Gin Trp Asn Val GI, Val Tyr 145 150 155 (2) INFORMATION FOR SEQ ID NO: 344: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 2192 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..2192 (D) OTHER INFORMATION: / Ceres Seq. ID 1974419
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:344: aattcaagtc atctctatcc gtcaacaata caaaccaacc ttctcaattc ctctcttttc 60 atccacattt tcactagcta atggcttcta gttcaatgag cacctcatca tggacagcta 120 gagaggacaa gcaattcgaa atggcgttgg cgaaattcga caaggacact cctgaccgtt 180 ggcaaaaaat tgcaagggca gttggtggga aatcaactga agaagtaaag cgacactatg 240 aattgctcct tagggatgtg aatgacattg agtcaggacg ctatccacaa cctagattat 300 gttccgcggc ggcgatagct gctgcgttca cttcaatgtc gatgtcacag aaccgcgctt 360 acgctgactc gcgatttcgc tttcctttct tctcttcttc acctccggca gaagaatctc 420 caaccgatca taagtcttct tcgaattcta aatcggagac taaacctgac tccgatgagc 480 ctaaaggatc tggtttcgat cctgagtcat tggaaagagg tgctaaagct cttcgtgaaa 540 tcaatagctc tcctcattcc aaacaggtgt ttgatctaat gcgaaagcag gagaagactc 600 gattagctga attagcggct gagaaagaac ataatgaagc tattcaagct agcaaggaca 660 ttgaaagaca gcggaaattg gcagaggatc agagaaattt agtgcagcaa caggcccaag 720 cgaaagcgca aaatcttaga tatgaggatg agttggccag gaagagaatg cagacagata 780 atgaagctca gagacggcat aatgctgaat tggtttcgat gcaagaagca tcttctatac 840 ggaaagagaa agcaagaatt gccacggaag aacagattca agcacagcag cgcgagactg 900 agaaagagag agcggaactt gagcgagaaa caattcgcgt gaaagctatg gctgaggctg 960 aaggccgagc tcatgaagct aaactcactg aggagcagaa tagaagaatg cttctagata 1020 agataaatgg tgaaagggag aaatggcttg cagcaatcaa cacgactttc agtcacattg 1080 aaggaggagt aaggacctta ttaactgatc gaagtaaatt gattatgact gttggaggag 1140 ttacggcatt agccgctggg gtttacacaa ctcgagaagg tgctagggtt acctggggtt 1200 atatcaatag aattcttggg cagccatcac tgatcagaga atcttccatg ggccgattcc 1260 catgggcagg ctcagtgtct cagtttaaga acaaacttag cacagctgca ggggcagcag 1320 catctgcaga aggagaaaag cctcttgaaa atgtaattct ccatcgttct ttgaagacga 1380 gaattgagcg tcttgcaaga gccacagcaa ataccaagtc acataaagca ccattccgaa 1440 acatgatgtt ttatgggcct ccaggtaccg gaaaaactat ggtggcgagg gagattgctc 1500 ggaagtcggg tcttgattat gctatgatga caggaggaga tgttgctcct cttggtgcac 1560 aggctgttac aaagatccat gaaatatttg attgggctaa gaaatcaaac aaagggttac 1620 tgcttttcat cgatgaagct gatgctttcc tatgcgaacg taacagcact tacatgagtg 1680 aggctcagcg cagcgctctg aacgcgttgc tctttcgaac cggtgatcaa tcgcgggaca 1740 tagtccttgt cctggctaca aacagacctg gagatctcga cagtgcagtc actgacagga 1800 tcgacgaagt tatcgagttt cctctccctg gtgaagaaga acgcttcaag ctcctcaagc 1860 tctatctcaa caagtaccta atgggtgacg acaagaaagg tgagaaagac tcaaacctta 1920 aatggagcaa cttgttcaag aagaagaagt cacagaagat aaccattgaa ggagacctaa 1980 ccgaccaagt gattaaagaa gctgcaaaaa agacagaagg cttttctggt cgtgaaatcg 2040 ctaagcttgt cgccggtgtt caagctgcgg tatatggacg acaggattgt gtcttggatt 2100 cccaactttt tgaagaaatt gtggattata agatcgaaga acatcaccag agaatcagac 2160 ttgcgactga aggtggccaa tcgtttccgt ag (2) INFORMATION FOR SEQ ID NO:345: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 703 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..703
(D) OTHER INFORMATION: / Ceres Seq. ID 1974420 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 345: Met Ala Ser Ser Ser Met Ser Thr Ser Ser Trp Thr Ala Arg Glu Asp 1 5 10 15
Lys Gin Phe Glu Met Ala Leu Ala Lys Phe Asp Lys Asp Thr Pro Asp
20 25 30
Arg Trp Gin Lys He Ala Arg Ala Val Gly Gly Lys Ser Thr Glu Glu 35 40 45 Val Lys Arg His Tyr Glu Leu Leu Leu Arg Asp Val Asn Asp He Glu 50 " 55 60
Ser Gly Arg Tyr Pro Gin Pro Arg Leu Cys Ser Ala Ala Ala He Ala 65 70 75 80
Ala Ala Phe Thr Ser Met Ser Met Ser Gin Asn Arg Ala Tyr Ala Asp 85 90 95
Ser Arg Phe Arg Phe Pro Phe Phe Ser Ser Ser Pro Pro Ala Glu Glu
100 105 110
Ser Pro Thr Asp His Lys Ser Ser Ser Asn Ser Lys Ser Glu Thr Lys 115 120 125 Pro Asp Ser Asp Glu Pro Lys Gly Ser Gly Phe Asp Pro Glu Ser Leu 130 135 140
Glu Arg Gly Ala Lys Ala Leu Arg Glu He Asn Ser Ser Pro His Ser 145 ' 150 155 160
Lys Gin Val Phe Asp Leu Met Arg Lys Gin Glu Lys Thr Arg Leu Ala 165 170 175
Glu Leu Ala Ala Glu Lys Glu His Asn Glu Ala He Gin Ala Ser Lys
180 185 190
Asp He Glu Arg Gin Arg Lys Leu Ala Glu Asp Gin Arg Asn Leu Val 195 200 205 Gin Gin Gin Ala Gin Ala Lys Ala Gin Asn Leu Arg Tyr Glu Asp Glu 210 215 220
Leu Ala Arg Lys Arg Met Gin Thr Asp Asn Glu Ala Gin Arg Arg His 225 230 235 240
Asn Ala Glu Leu Val Ser Met Gin Glu Ala Ser Ser He Arg Lys Glu
245 250 255
Lys Ala Arg He Ala Thr Glu Glu Gin He Gin Ala Gin Gin Arg Glu 260 265 270
Thr Glu Lys Glu Arg Ala Glu Leu Glu Arg Glu Thr He Arg Val Lys
275 280 285
Ala Met Ala Glu Ala Glu Gly Arg Ala His Glu Ala Lys Leu Thr Glu
290 295 300 Glu Gin Asn Arg Arg Met Leu Leu Asp Lys He Asn Gly Glu Arg Glu
305 310 315 320
Lys Trp Leu Ala Ala He Asn Thr Thr Phe Ser His He Glu Gly Gly
325 330 335
Val Arg Thr Leu Leu Thr Asp Arg Ser Lys Leu He Met Thr Val Gly 340 345 350
Gly Val Thr Ala Leu Ala Ala Gly Val Tyr Thr Thr Arg Glu Gly Ala
355 360 365
Arg Val Thr Trp Gly Tyr He Asn Arg He Leu Gly Gin Pro Ser Leu
370 375 380 He Arg Glu Ser Ser Met Gly Arg Phe Pro Trp Ala Gly Ser Val Ser
385 390 395 400
Gin Phe Lys Asn Lys Leu Ser Thr Ala Ala Gly Ala Ala Ala Ser Ala
405 410 415
Glu Gly Glu Lys Pro Leu Glu Asn Val He Leu His Arg Ser Leu Lys 420 425 430
Thr Arg He Glu Arg Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser His
435 440 445
Lys Ala Pro Phe Arg Asn Met Met Phe Tyr Gly Pro Pro Gly Thr Gly
450 455 460 Lys Thr Met Val Ala Arg Glu He Ala Arg Lys Ser Gly Leu Asp Tyr
465 470 475 480
Ala Met Met Thr Gly Gly Asp al Ala Pro Leu Gly Ala Gin Ala Val
485 490 495
Thr Lys He His Glu He Phe Asp Trp Ala Lys Lys Ser Asn Lys Gly 500 505 510
Leu Leu Leu Phe He Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg Asn
515 520 525
Ser Thr Tyr Met Ser Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu Leu
530 535 540 Phe Arg Thr Gly Asp Gin Ser Arg Asp He Val Leu Val Leu Ala Thr
545 550 555 560
Asn Arg Pro Gly Asp Leu Asp Ser Ala Val Thr Asp Arg He Asp Glu
565 570 575
Val He Glu Phe Pro Leu Pro Gly Glu Glu Glu Arg Phe Lys Leu Leu 580 585 590
Lys Leu Tyr Leu Asn Lys Tyr Leu Met Gly Asp Asp Lys Lys Gly Glu
595 600 605
Lys Asp Ser Asn Leu Lys Trp Ser Asn Leu Phe Lys Lys Lys Lys Ser
610 615 620 Gin Lys He Thr He Glu Gly Asp Leu Thr Asp Gin Val He Lys Glu
625 630 635 640
Ala Ala Lys Lys Thr Glu Gly Phe Ser Gly Arg Glu He Ala Lys Leu
645 650 655
Val Ala Gly Val Gin Ala Ala Val Tyr Gly Arg Gin Asp Cys Val Leu 660 665 670
Asp Ser Gin Leu Phe Glu Glu He Val Asp Tyr Lys He Glu Glu His
675 680 " 685
His Gin Arg He Arg Leu Ala Thr Glu Gly Gly Gin Ser Phe Pro 690 695 700 (2) INFORMATION FOR SEQ ID NO:346: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 698 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..698
(D) OTHER INFORMATION: / Ceres Seq. ID 1974421 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 346: Met Ser Thr Ser Ser Trp Thr Ala Arg Glu Asp Lys Gin Phe Glu Met 1 5 10 15
Ala Leu Ala Lys Phe Asp Lys Asp Thr Pro Asp Arg Trp Gin Lys He
20 * 25 30
Ala Arg Ala Val Gly Gly Lys Ser Thr Glu Glu Val Lys Arg His Tyr 35 40 45
Glu Leu Leu Leu Arg Asp Val Asn Asp He Glu Ser Gly Arg Tyr Pro
50 55 60
Gin Pro Arg Leu Cys Ser Ala Ala Ala He Ala Ala Ala Phe Thr Ser 65 70 75 80 Met Ser Met Ser Gin Asn Arg Ala Tyr Ala Asp Ser Arg Phe Arg Phe
85 90 95
Pro Phe Phe Ser Ser Ser Pro Pro Ala Glu Glu Ser Pro Thr Asp His
100 105 110
Lys Ser Ser Ser Asn Ser Lys Ser Glu Thr Lys Pro Asp Ser Asp Glu 115 120 125
Pro Lys Gly Ser Gly Phe Asp Pro Glu Ser Leu Glu Arg Gly Ala Lys
130 135 140
Ala Leu Arg Glu He Asn Ser Ser Pro His Ser Lys Gin Val Phe Asp 145 150 155 160 Leu Met Arg Lys Gin Glu Lys Thr Arg Leu Ala Glu Leu Ala Ala Glu
165 170 175
Lys Glu His Asn Glu Ala He Gin Ala Ser Lys Asp He Glu Arg Gin
180 185 190
Arg Lys Leu Ala Glu Asp Gin Arg Asn Leu Val Gin Gin Gin Ala Gin 195 200 205
Ala Lys Ala Gin Asn Leu Arg Tyr Glu Asp Glu Leu Ala Arg Lys Arg
210 215 220
Met Gin Thr Asp Asn Glu Ala Gin Arg Arg His Asn Ala Glu Leu Val 225 230 235 240 Ser Met Gin Glu Ala Ser Ser He Arg Lys Glu Lys Ala Arg He Ala
245 250 255
Thr Glu Glu Gin He Gin Ala Gin Gin Arg Glu Thr Glu Lys Glu Arg
260 265 270
Ala Glu Leu Glu Arg Glu Thr He Arg Val Lys Ala Met Ala Glu Ala 275 280 285
Glu Gly Arg Ala His Glu Ala Lys Leu Thr Glu Glu Gin Asn Arg Arg
290 295 300
Met Leu Leu Asp Lys He Asn Gly Glu Arg Glu Lys Trp Leu Ala Ala 305 310 315 320 He Asn Thr Thr Phe Ser His He Glu Gly Gly Val Arg Thr Leu Leu
325 330 335
Thr Asp Arg Ser Lys Leu He Met Thr Val Gly Gly Val Thr Ala Leu
340 345 350
Ala Ala Gly Val Tyr Thr Thr Arg Glu Gly Ala Arg Val Thr Trp Gly 355 360 365
Tyr He Asn Arg He Leu Gly Gin Pro Ser Leu He Arg Glu Ser Ser
370 375 380
Met Gly Arg Phe Pro Trp Ala Gly Ser Val Ser Gin Phe Lys Asn Lys 385 390 395 400 Leu Ser Thr Ala Ala Gly Ala Ala Ala Ser Ala Glu Gly Glu Lys Pro
405 410 415
Leu Glu Asn Val He Leu His Arg Ser Leu Lys Thr Arg He Glu Arg 420 425 430
Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser His Lys Ala Pro Phe Arg
435 440 445
Asn Met Met Phe Tyr Gly Pro Pro Gly Thr Gly Lys Thr Met Val Ala 450 455 460
Arg Glu He Ala Arg Lys Ser Gly Leu Asp Tyr Ala Met Met Thr Gly
465 470 475 480
Gly Asp Val Ala Pro Leu Gly Ala Gin Ala Val Thr Lys He His Glu
485 490 495 He Phe Asp Trp Ala Lys Lys Ser Asn Lys Gly Leu Leu Leu Phe He
500 505 510
Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg Asn Ser Thr Tyr Met Ser
515 520 525
Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu Leu Phe Arg Thr Gly Asp 530 535 540
Gin Ser Arg Asp He Val Leu Val Leu Ala Thr Asn Arg Pro Gly Asp
545 550 555 560
Leu Asp Ser Ala Val Thr Asp Arg He Asp Glu Val He Glu Phe Pro
565 570 575 Leu Pro Gly Glu Glu Glu Arg Phe Lys Leu Leu Lys Leu Tyr Leu Asn
580 585 590
Lys Tyr Leu Met Gly Asp Asp Lys Lys Gly Glu Lys Asp Ser Asn Leu
595 600 605
Lys Trp Ser Asn Leu Phe Lys Lys Lys Lys Ser Gin Lys He Thr He 610 615 620
Glu Gly Asp Leu Thr Asp Gin Val He Lys Glu Ala Ala Lys Lys Thr
625 630 635 640
Glu Gly Phe Ser Gly Arg Glu He Ala Lys Leu Val Ala Gly Val Gin
645 650 655 Ala Ala Val Tyr Gly Arg Gin Asp Cys Val Leu Asp Ser Gin Leu Phe
660 665 670
Glu Glu He Val Asp Tyr Lys He Glu Glu His His Gin Arg He Arg
675 680 685
Leu Ala Thr Glu Gly Gly Gin Ser Phe Pro 690 695
(2) INFORMATION FOR SEQ ID NO: 347: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 683 amino acids (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..683
(D) OTHER INFORMATION: / Ceres Seq. ID 1974422 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 347: Met Ala Leu Ala Lys Phe Asp Lys Asp Thr Pro Asp Arg Trp Gin Lys 1 5 10 15 He Ala Arg Ala Val Gly Gly Lys Ser Thr Glu Glu Val Lys Arg His 20 25 30
Tyr Glu Leu Leu Leu Arg Asp Val Asn Asp He Glu Ser Gly Arg Tyr
35 40 45
Pro Gin Pro Arg Leu Cys Ser Ala Ala Ala He Ala Ala Ala Phe Thr 50 55 60
Ser Met Ser Met Ser Gin Asn Arg Ala Tyr Ala Asp Ser Arg Phe Arg 65 70 75 80
Phe Pro Phe Phe Ser Ser Ser Pro Pro Ala Glu Glu Ser Pro Thr Asp 85 90 95 His Lys Ser Ser Ser Asn Ser Lys Ser Glu Thr Lys Pro Asp Ser Asp 100 105 110
Glu Pro Lys Gly Ser Gly Phe Asp Pro Glu Ser Leu Glu Arg Gly Ala 115 120 125
Lys Ala Leu Arg Glu He Asn Ser Ser Pro His Ser Lys Gin Val Phe
130 135 140
Asp Leu Met Arg Lys Gin Glu Lys Thr Arg Leu Ala Glu Leu Ala Ala 145 " 150 155 160
Glu Lys Glu His Asn Glu Ala He Gin Ala Ser Lys Asp He Glu Arg
165 170 175
Gin Arg Lys Leu Ala Glu Asp Gin Arg Asn Leu Val Gin Gin Gin Ala 180 185 190 Gin Ala Lys Ala Gin Asn Leu Arg Tyr Glu Asp Glu Leu Ala Arg Lys 195 200 205
Arg Met Gin Thr Asp Asn Glu Ala Gin Arg Arg His Asn Ala Glu Leu
210 215 220
Val Ser Met Gin Glu Ala Ser Ser He Arg Lys Glu Lys Ala Arg He 225 230 235 240
Ala Thr Glu Glu Gin He Gin Ala Gin Gin Arg Glu Thr Glu Lys Glu
245 250 255
Arg Ala Glu Leu Glu Arg Glu Thr He Arg Val Lys Ala Met Ala Glu 260 265 270 Ala Glu Gly Arg Ala His Glu Ala Lys Leu Thr Glu Glu Gin Asn Arg 275 280 285
Arg Met Leu Leu A.sp Lys He Asn Gly Glu Arg Glu Lys Trp Leu Ala
290 295 300
Ala He Asn Thr Thr Phe Ser His He Glu Gly Gly Val Arg Thr Leu 305 310 315 320
Leu Thr Asp Arg Ser Lys Leu He Met Thr Val Gly Gly Val Thr Ala
325 330 335
Leu Ala Ala Gly Val Tyr Thr Thr Arg Glu Gly Ala Arg Val Thr Trp 340 345 350 Gly Tyr He Asn Arg He Leu Gly Gin Pro Ser Leu He Arg Glu Ser 355 360 365
Ser Met Gly Arg Phe Pro Trp Ala Gly Ser Val Ser Gin Phe Lys Asn
370 375 380
Lys Leu Ser Thr Ala Ala Gly Ala Ala Ala Ser Ala Glu Gly Glu Lys 385 390 395 400
Pro Leu Glu Asn Val He Leu His Arg Ser Leu Lys Thr Arg He Glu
405 410 415
A_rg Leu Ala Arg Ala Thr Ala Asn Thr Lys Ser His Lys Ala Pro Phe 420 425 430 Arg Asn Met Met Phe Tyr Gly Pro Pro Gly Thr Gly Lys Thr Met Val 435 440 445
Ala Arg Glu He Ala Arg Lys Ser Gly Leu Asp Tyr Ala Met Met Thr
450 455 460
Gly Gly Asp Val Ala Pro Leu Gly Ala Gin Ala Val Thr Lys He His 465 470 475 480
Glu He Phe Asp Trp Ala Lys Lys Ser Asn Lys Gly Leu Leu Leu Phe
485 490 495
He Asp Glu Ala Asp Ala Phe Leu Cys Glu Arg Asn Ser Thr Tyr Met 500 505 510 Ser Glu Ala Gin Arg Ser Ala Leu Asn Ala Leu Leu Phe Arg Thr Gly 515 ' 520 525
Asp Gin Ser Arg Asp He Val Leu Val Leu Ala Thr Asn Arg Pro Gly
530 535 540
Asp Leu Asp Ser Ala Val Thr Asp Arg He Asp Glu Val He Glu Phe 545 550 555 560
Pro Leu Pro Gly Glu Glu Glu A_rg Phe Lys Leu Leu Lys Leu Tyr Leu
565 570 575
Asn Lys Tyr Leu Met Gly Asp Asp Lys Lys Gly Glu Lys Asp Ser Asn 580 585 590 Leu Lys Trp Ser Asn Leu Phe Lys Lys Lys Lys Ser Gin Lys He Thr 595 600 605
He Glu Gly Asp Leu Thr Asp Gin Val He Lys Glu Ala Ala Lys Lys 610 615 620
Thr Glu Gly Phe Ser Gly Arg Glu He Ala Lys Leu Val Ala Gly Val 625 630 635 640
Gin Ala Ala Val Tyr Gly Arg Gin Asp Cys Val Leu Asp Ser Gin Leu
645 650 655
Phe Glu Glu He Val Asp Tyr Lys He Glu Glu His His Gin Arg Ho
660 665 670
Arg Leu Ala Thr Glu Gly Gly Gin Ser Phe Pro 675 680
(2) INFORMATION FOR SEQ ID NO: 348:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 953 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..953 (D) OTHER INFORMATION: / Ceres Seq. ID 1975983 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 348: aaaaaaσata aaacaaaagc tgaaaggagg aaaccagagg aaggagacga cgaccaccac 60 cacaacgcat ctcagctctt ccttaatcca tggcagacaa gggccgcccg ttgccgaagt 120 ttggaagagc tgagatgcgt tgtggtggtg gcgtcgcctc cttcttcaat ctcatcgcaa 180 tcatgatcat atccgagact aatcgccgtg agatctccaa gtacctcttc aaagagggtg 240 ttttgtttgc caaaaaggat ttcaatttac cacaacatcc tttgattgag agtgttccaa 300 atctgcaagt tatcaagttg atgcagagtt tcaaatctaa ggaatatgtg agagagacct 360 ttgcttggat gcattactac tggttcctca caaatgaagg tattgacttt cttaggactt 420 accttaatct cccatctgag attgttcctg ctactctgaa gaagcaacag aagcctcttg 480 gtcgaccttt tggaggtggt ggtgaccgtc cccgtggccc tcctcgtggt gatggagaga 540 ggaggtttgg tgacagagat ggataccgtg gaggtcctaa atcaggtgga gagtatggtg 600 acaaggctgg agcacctgct gattaccagc ctggcttcag gggtggagct agtggagcaa 660 ggcaagggtt tggtcgtgga gctggtggtt ttggtggtgg tgctggtcca gctgctggat 720 ctgatctacc ttgaaaagga ctttcttgtt tctttttggt cttatttaag gttacatagc 780 accttattga gaacgaatgt gtcttttgga actttgtttc tttctcttaa accatttcac 840 aatatgattg tttttttacg ttagaatttt atgaagaaat gttggatcgt tacatgaatc 900 tttttacact gtcctccttt ttaaattctc ctatttagtt tttttcgaag ctt (2) INFORMATION FOR SEQ ID NO: 349: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 214 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..214 (D) OTHER INFORMATION: / Ceres Seq. ID 1975984
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:349: Met Ala Asp Lys Gly Arg Pro Leu Pro Lys Phe Gly Arg Ala Glu Met 1 5 10 15
Arg Cys Gly Gly Gly Val Ala Ser Phe Phe Asn Leu He Ala He Met
20 25 30
He He Ser Glu Thr Asn Arg Arg Glu He Ser Lys Tyr Leu Phe Lys
35 40 45
Glu Gly Val Leu Phe Ala Lys Lys Asp Phe Asn Leu Pro Gin His Pro
50 55 60
Leu He Glu Ser Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser 65 70 75 80
Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His Tyr
85 90 95
Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu Arg Thr Tyr Leu 100 105 110
Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys Gin Gin Lys
115 120 125
Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro Arg Gly Pro 130 135 140
Pro Arg Gly Asp Gly Glu Arg Arg Phe Gly Asp Arg Asp Gly Tyr Arg
145 150 155 160
Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lys Ala Gly Ala Pro
165 170 175 Ala Asp Tyr Gin Pro Gly Phe Arg Gly Gly Ala Ser Gly Ala Arg Gin
180 185 190
Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala Gly Pro Ala
195 200 205
Ala Gly Ser Asp Leu Pro 210
(2) INFORMATION FOR SEQ ID NO: 350: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 199 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..199
(D) OTHER INFORMATION: / Ceres Seq. ID 1975985 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 350: Met Arg Cys Gly Gly Gly Val Ala Ser Phe Phe Asn Leu He Ala He 1 5 10 15 Met He He Ser Glu Thr Asn Arg Arg Glu He Ser Lys Tyr Leu Phe 20 25 30
Lys Glu Gly Val Leu Phe Ala Lys Lys Asp Phe Asn Leu Pro Gin His
35 40 45
Pro Leu He Glu Ser Val Pro Asn Leu Gin Val He Lys Leu Met Gin 50 55 60
Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His 65 " 70 75 80
Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu A.rg Thr Tyr 85 90 95 Leu Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys Gin Gin
100 105 110
Lys Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro Arg Gly
115 120 125
Pro Pro Arg Gly Asp Gly Glu Arg Arg Phe Gly Asp Arg Asp Gly Tyr 130 135 140
Arg Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lys Ala Gly Ala 145 150 155 160
Pro Ala Asp Tyr Gin Pro Gly Phe Arg Gly Gly Ala Ser Gly Ala Arg 165 170 175 Gin Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala Gly Pro 180 185 190
Ala Ala Gly Ser Asp Leu Pro
195 (2) INFORMATION FOR SEQ ID NO: 351: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 183 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..183
(D) OTHER INFORMATION: / Ceres Seq. ID 1975986 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 351: Met He He Ser Glu Thr Asn Arg Arg Glu He Ser Lys Tyr Leu Phe 1 5 10 15
Lys Glu Gly Val Leu Phe Ala Lys Lys Asp Phe Asn Leu Pro Gin His
20 25 30
Pro Leu He Glu Ser Val Pro Asn Leu Gin Val He Lys Leu Met Gin 35 40 45 Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His 50 55 60
Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu Arg Thr Tyr 65 " 70 75 80
Leu Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys Gin Gin 85 90 95
Lys Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro Arg Gly
100 105 110
Pro Pro Arg Gly Asp Gly Glu Arg Arg Phe Gly Asp Arg Asp Gly Tyr 115 120 125 Arg Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lys Ala Gly Ala 130 135 140
Pro Ala Asp Tyr Gin Pro Gly Phe Arg Gly Gly Ala Ser Gly Ala Arg 145 " 150 155 " 160
Gin Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala Gly Pro 165 170 175
Ala Ala Gly Ser Asp Leu Pro
180 (2) INFORMATION FOR SEQ ID NO: 352: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1027 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1027
(D) OTHER INFORMATION: / Ceres Seq. ID 1976019 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:352: atcgaaatta gggtttcgcg ttaggagaag aagttaaagc aaaacacata caaacgcagt 60 caccttctct gtcgcctcct tcttcaatct catcgcaatc atgatcatat ccgagactaa 120 tcgccgtgag atctccaagt acctcttcaa agagggtgtt ttgtttgcca aaaaggattt 180 caatttacca caacatcctt tgattgagag tgttccaaat ctgcaagtta tcaagttgat 240 gcagagtttc aaatctaagg aatatgtgag agagaccttt gcttggatgc attactactg 300 gttcctcaca aatgaaggta ttgactttct taggacttac cttaatctcc catctgagat 360 tgttcctgct actctgaaga agcaacagaa gcctcttggt cgaccttttg gaggtggtgg 420 tgaccgtccc cgtggccctc ctcgtggtga tggagagagg aggtttggtg acagagatgg 480 ataccgtgga ggtcctaaat caggtggaga gtatggtgac aaggctggag cacctgctga 540 ttaccagcct ggcttcaggg gtggagctag tggagcaagg caagggtttg gtcgtggagc 600 tggtggtttt ggtggtggtg ctggtccagc tgctggatct gatctacctt gaaaaggaga 660 caatacagct cagccaaagc caaggccttt atcaccttac acaatgtacg cggacatgaa 720 gcctccaaca tcaccacttc catctccagt caccaatcat tagctatgtg agacgagaat 780 tggcctccta aaccctggag cttcttctta attgcaggtt gtaaacaatg agtaagagag 840 tgatggggca attcagtttt gcaggtatga atcagtgagc ttatttgtac aataatacaa 900 tattcatcaa catgccttat atatgagttc tacttttttt ctcctgttca acgatcaatg 960 cagtaaccat attgttaccc tatctcatac atatatgatg acccaaatta attatcatta 1020 ggctttc
(2) INFORMATION FOR SEQ ID NO: 353: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 183 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..183
(D) OTHER INFORMATION: / Ceres Seq. ID 1976020 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 353: Met He He Ser Glu Thr Asn Arg Arg Glu He Ser Lys Tyr Leu Phe 1 5 10 15 Lys Glu Gly Val Leu Phe Ala Lys Lys Asp Phe Asn Leu Pro Gin His
20 25 30
Pro Leu He Glu Ser Val Pro Asn Leu Gin Val He Lys Leu Met Gin
35 40 45
Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His 50 55 60
Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu Arg Thr Tyr 65 70 75 80
Leu Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys Gin Gin 85 90 95 Lys Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro Arg Gly
100 105 110
Pro Pro Arg Gly Asp Gly Glu Arg Arg Phe Gly Asp Arg Asp Gly Tyr
115 120 125
Arg Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lys Ala Glv Ala 130 135 140
Pro Ala Asp Tyr Gin Pro Gly Phe Arg Gly Gly Ala Ser Gly Ala Arg 145 150 155 160
Gin Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala Gly Pro 165 170 175 Ala Ala Gly Ser Asp Leu Pro
180 (2) INFORMATION FOR SEQ ID NO: 354: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 137 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..137
(D) OTHER INFORMATION: / Ceres Seq. ID 1976021 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 354: Met Gin Ser Phe Lys Ser Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp 1 5 10 15
Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu Arg
20 25 30
Thr Tyr Leu Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys 35 40 45 Gin Gin Lys Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro 50 55 60
Arg Gly Pro Pro Arg Gly Asp Gly Glu Arg Arσ Phe Gly Asp Arg Asp 65 70 75 80
Gly Tyr Arg Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lvs Ala 85 90 95
Gly Ala Pro Ala Asp Tyr Gin Pro Gly Phe Arg Gly Gly Ala Ser Gly
100 105 110
Ala Arg Gin Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala 115 120 125 Gly Pro Ala Ala Gly Ser Asp Leu Pro 130 135
(2) INFORMATION FOR SEQ ID NO: 355: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 121 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..121
(D) OTHER INFORMATION: / Ceres Seq. ID 1976022
(XI) SEQUENCE DESCRIPTION: SEQ ID NO: 355:
Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Asp Phe Leu Arg
1 5 10 15
Thr Tyr Leu Asn Leu Pro Ser Glu He Val Pro Ala Thr Leu Lys Lys 20 25 30
Gin Gin Lys Pro Leu Gly Arg Pro Phe Gly Gly Gly Gly Asp Arg Pro 35 40 45
Arg Gly Pro Arg Gly Asp Gly Glu Arg Arg Phe Gly Asp Arg Asp 50 55 60
Glv Tyr Arg Gly Gly Pro Lys Ser Gly Gly Glu Tyr Gly Asp Lys Ala
65 70 75 80
Gly Ala Pro Ala A.sp Tyr Gin Gly Phe Arg Gly Gly Ala Ser Gly 85 90 95
Ala Arg Gin Gly Phe Gly Arg Gly Ala Gly Gly Phe Gly Gly Gly Ala
100 105 110
Gly Pro Ala Ala Gly Ser Asp Leu Pro
115 120 (2) INFORMATION FOR SEQ ID NO: 356: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 478 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..478 (D) OTHER INFORMATION: / Ceres Seq. ID 1976673
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 356: aaattcaatc tcttccaatt tctcttcttc ttcctcgcga cgcgttaatg gcggcttcgt 60 tctcactcac gagcttcatc tccttcatct caccattcaa atctcaaacc aaacctacac 120 caccaccaaa tctcactctt ccttctccaa ctatctccca aaggcgaaga aatgatctcg 180 ctatcgaatc aatggcggtc gaagaatctt cttcaaccgc ttcttcactt tcctctgagc 240 ttgcttctgt gatatgcccc tcgcttgctt actccaacac gctcttcttc agttctggat 300 acaatgtgca agtgtttgtt gaagataacg agtcagagga gaggcttgtg aatcgattta 360 ggagagaagt gatgagaact ggtgttatac aggaatgtaa gaggagaaga tactttgaga 420 ataaacaaga tgagaagaaa cgtaggactc gtgatgctgc taagcgtaat aagaaaag (2) INFORMATION FOR SEQ ID NO: 357:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 158 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..158
(D) OTHER INFORMATION: / Ceres Seq. ID 1976674 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 357:
He Gin Ser Leu Pro He Ser Leu Leu Leu Pro Arg Asp Ala Leu Met
1 5 10 15
Ala Ala Ser Phe Ser Leu Thr Ser Phe He Ser Phe He Ser Pro Phe 20 25 30
Lys Ser Gin Thr Lys Pro Thr Pro Pro Pro Asn Leu Thr Leu Pro Ser
35 40 45
Pro Thr He Ser Gin Arg Arg Arg Asn Asp Leu Ala He Glu Ser Met 50 55 60
Ala Val Glu Glu Ser Ser Ser Thr Ala Ser Ser Leu Ser Ser Glu Leu 65 70 75 80
Ala Ser Val He Cys Pro Ser Leu Ala Tyr Ser Asn Thr Leu Phe Phe 85 90 95 Ser Ser Gly Tyr Asn Val Gin Val Phe Val Glu Asp Asn Glu Ser Glu
100 105 110
Glu Arg Leu Val Asn Arg Phe Arg Arg Glu Val Met Arg Thr Gly Val
115 120 125
He Gin Glu Cys Lys Arg Arg Arg Tyr Phe Glu Asn Lys Gin Asp Glu 130 135 " 140
Lys Lys Arg Arg Thr Arg Asp Ala Ala Lys Arg Asn Lys Lys 145 " 150 155
(2) INFORMATION FOR SEQ ID NO: 358: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 143 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..143
(D) OTHER INFORMATION: / Ceres Seq. ID 1976675 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 358: Met Ala Ala Ser Phe Ser Leu Thr Ser Phe He Ser Phe He Ser Pro 1 5 10 15
Phe Lys Ser Gin Thr Lys Pro Thr Pro Pro Pro Asn Leu Thr Leu Pro
20 25 30
Ser Pro Thr He Ser Gin Arg Arg Arg Asn Asp Leu Ala He Glu Ser 35 40 45
Met Ala Val Glu Glu Ser Ser Ser Thr Ala Ser Ser Leu Ser Ser Glu
50 55 60
Leu Ala Ser Val He Cys Pro Ser Leu Ala Tyr Ser Asn Thr Leu Phe 65 70 75 80 Phe Ser Ser Gly Tyr Asn Val Gin Val Phe Val Glu Asp Asn Glu Ser
85 90 95
Glu Glu Arg Leu Val Asn Arg Phe Arg Arg Glu Val Met Arg Thr Gly
100 105 110
Val He Gin Glu Cys Lys Arg Arg Arg Tyr Phe Glu Asn Lys Gin Asp 115 120 125
Glu Lys Lys Arg Arg Thr Arg Asp Ala Ala Lys Arg Asn Lys Lys
130 135 140
(2) INFORMATION FOR SEQ ID NO:359: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 95 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..95
(D) OTHER INFORMATION: / Ceres Seq. ID 1976676 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 359: Met Ala Val Glu Glu Ser Ser Ser Thr Ala Ser Ser Leu Ser Ser Glu 1 5 10 15
Leu Ala Ser Val He Cys Pro Ser Leu Ala Tyr Ser Asn Thr Leu Phe 20 25 30
Phe Ser Ser Gly Tyr Asn Val Gin Val Phe Val Glu Asp Asn Glu Ser
35 40 45
Glu Glu Arg Leu Val Asn Arg Phe Arg Arg Glu Val Met Arg Thr Gly 50 55 60
Val He Gin Glu Cys Lys Arg Arg Arg Tyr Phe Glu Asn Lys Gin Asp 65 70 75 80
Glu Lys Lys Arg Arg Thr Arg Asp Ala Ala Lys Arg Asn Lys Lys 85 90 95 (2) INFORMATION FOR SEQ ID NO:360: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1076 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1076 (D) OTHER INFORMATION: / Ceres Seq. ID 2025186
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 360: aatcatttgc agaagaaaaa taaaaaaaaa aaacagagaa aaggagata ggaatcaatc 60 ggagtcctta tgatgtgccc catgtcctcc tacctcgaga acgagcttga gaagcgcttc 120 aaccttcttc gcttctggac ttctccggag aaatccgtcc tcctagaaac tcatcggaac 180 tccatccgcg ccgtcgttgg gaatgcttct gccggcgccg atgctcagct catcagcgat 240 ctgcccaacc ttgagattgt atccagcttc agcgtcgggc tcgacaagat cgatttgggg 300 aaatgcaaag aaaaagggat ccgcgtcacc aacacccccg acgttctcac cgaagacgtc 360 gcagatctcg ccatcgggct tatcctggct ctccttcgac ggctgtgtga gtgcgatcgc 420 tatgtaagga gcggaaaatg gaagcaaggt gaattccaac tcactaccaa gtttagtgga 480 aaatccgtgg ggatcattgg tctaggtaga attgggactg ccatcgcaaa gagggctgaa 540 gcctttagct gcccaatcaa ttactactca agaaccatta agcctgatgt cgcctacaag 600 tattatccga cggtggttga ccttgctcaa aactcagaca tcctcgtcgt cgcatgcccg 660 ttgaccgagc agaccagaca cattgtggac cggcaggtca tggatgcatt aggagctaag 720 ggcgtcctca taaacattgg ccgtggacca catgttgatg agcaagagct tattaaagct 780 ctaacagaag gccgcctagg tggggctgcc cttgatgtgt ttgagcagga gcctcacgtg 840 cccgaggagc tctttggcct tgagaatgta gttctcctcc ctcacgttgg gagtggcact 900 gtggaaacac ggaatgccat ggccgatctt gtcgtgggta acttggaagc gcacttttct 960 gggaaatcac ttctgactcc ggtcgtctga gtcatgtgac acatttggga tttggtttca 1020 cttcatttga aaggttttta tgttaacgaa ctcatgaaaa gggtaatttc tcttcc (2) INFORMATION FOR SEQ ID NO: 361: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 329 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..329 (D) OTHER INFORMATION: / Ceres Seq. ID 2025187
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 361: Asn His Leu Gin Lys Lys Asn Lys Lys Lys Lys Gin Arg Lys Gly Asp 1 5 10 15
Met Glu Ser He Gly Val Leu Met Met Cys Pro Met Ser Ser Tyr Leu 20 25 30
Glu Asn Glu Leu Glu Lys Arg Phe Asn Leu Leu Arg Phe Trp Thr Ser
35 40 45
Pro Glu Lys Ser Val Leu Leu Glu Thr His Arg Asn Ser He Arg Ala 50 55 60 Val Val Gly Asn Ala Ser Ala Gly Ala Asp Ala Gin Leu He Ser Asp 65 70 75 80
Leu Pro Asn Leu Glu He Val Ser Ser Phe Ser Val Gly Leu Asp Lys 85 90 95
He Asp Leu Gly Lys Cys Lys Glu Lys Gly He Arg Val Thr Asn Thr
100 105 110
Pro Asp Val Leu Thr Glu Asp Val Ala Asp Leu Ala He Gly Leu He 115 120 125
Leu Ala Leu Leu Arg Arg Leu Cys Glu Cys Asp Arg Tyr Val Arg Ser
130 135 140
Gly Lys Trp Lys Gin Gly Glu Phe Gin Leu Thr Thr Lys Phe Ser Gly 145 150 155 160 Lys Ser Val Gly He He Gly Leu Gly Arg He Gly Thr Ala He Ala
165 170 175
Lys Arg Ala Glu Ala Phe Ser Cys Pro He Asn Tyr Tyr Ser Arg Thr
180 185 190
He Lys Pro Asp Val Ala Tyr Lys Tyr Tyr Pro Thr Val Val Asp Leu 195 200 205
Ala Gin Asn Ser Asp He Leu Val Val Ala Cys Pro Leu Thr Glu Gin
210 215 220
Thr Arg His He Val Asp Arg Gin Val Met Asp Ala Leu Gly Ala Lys 225 230 235 240 Gly Val Leu He Asn He Gly Arg Gly Pro His Val Asp Glu Gin Glu
245 250 255
Leu He Lys Ala Leu Thr Glu Gly Arg Leu Gly Gly Ala Ala Leu Asp
260 265 270
Val Phe Glu Gin Glu Pro His Val Pro Glu Glu Leu Phe Gly Leu Glu 275 280 285
Asn Val Val Leu Leu Pro His Val Gly Ser Gly Thr Val Glu Thr Arg
290 295 300
Asn Ala Met Ala Asp Leu Val Val Gly Asn Leu Glu Ala His Phe Ser 305 310 315 320 Gly Lys Ser Leu Leu Thr Pro Val Val
325 (2) INFORMATION FOR SEQ ID NO: 362: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 313 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..313
(D) OTHER INFORMATION: / Ceres Seq. ID 2025188 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:362: Met Glu Ser He Gly Val Leu Met Met Cys Pro Met Ser Ser Tyr Leu 1 5 10 15
Glu Asn Glu Leu Glu Lys Arg Phe Asn Leu Leu Arg Phe Trp Thr Ser
20 25 30
Pro Glu Lys Ser Val Leu Leu Glu Thr His Arg Asn Ser He Arg Ala 35 40 45 Val Val Gly Asn Ala Ser Ala Gly Ala Asp Ala Gin Leu He Ser Asp 50 55 60
Leu Pro Asn Leu Glu He Val Ser Ser Phe Ser Val Gly Leu Asp Lys 65 70 75 80
He Asp Leu Gly Lys Cys Lys Glu Lys Gly He Arg Val Thr Asn Thr 85 90 95
Pro Asp Val Leu Thr Glu Asp Val Ala Asp Leu Ala He Gly Leu He
100 105 110
Leu Ala Leu Leu Arg Arg Leu Cys Glu Cys Asp Arg Tyr Val Arg Ser 115 120 125 Gly Lys Trp Lys Gin Gly Glu Phe Gin Leu Thr Thr Lys Phe Ser Gly 130 135 140
Lys Ser Val Gly He He Gly Leu Gly Arg He Gly Thr Ala He Ala 145 150 155 160
Lys Arg Ala Glu Ala Phe Ser Cys Pro He Asn Tyr Tyr Ser Arg Thr
165 170 175
He Lys Pro Asp Val Ala Tyr Lys Tyr Tyr Pro Thr Val Val Asp Leu 180 185 190
Ala Gin Asn Ser Asp He Leu Val Val Ala Cys Pro Leu Thr Glu Gin
195 200 205
Thr Arg His He Val Asp Arg Gin Val Met Asp Ala Leu Gly Ala Lys
210 215 220 Gly Val Leu He Asn He Gly Arg Gly Pro His Val Asp Glu Gin Glu
225 230 235 240
Leu He Lys Ala Leu Thr Glu Gly Arg Leu Gly Gly Ala Ala Leu Asp
245 250 255
Val Phe Glu Gin Glu Pro His Val Pro Glu Glu Leu Phe Gly Leu Glu 260 265 270
Asn Val Val Leu Leu Pro His Val Gly Ser Gly Thr Val Glu Thr Arg
275 280 285
Asn Ala Met Ala Asp Leu Val Val Gly Asn Leu Glu Ala His Phe Ser 290 295 300 Gly Lys Ser Leu Leu Thr Pro Val Val 305 " 310
(2) INFORMATION FOR SEQ ID NO: 363: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 306 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..306
(D) OTHER INFORMATION: / Ceres Seq. ID 2025189 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 363: Met Met Cys Pro Met Ser Ser Tyr Leu Glu Asn Glu Leu Glu Lys Arg 1 5 10 15
Phe Asn Leu Leu Arg Phe Trp Thr Ser Pro Glu Lys Ser Val Leu Leu
20 25 30
Glu Thr His Arg Asn Ser He Arg Ala Val Val Gly Asn Ala Ser Ala 35 40 45 Gly Ala Asp Ala Gin Leu He Ser Asp Leu Pro Asn Leu Glu He Val 50 55 60
Ser Ser Phe Ser Val Gly Leu Asp Lys He Asp Leu Gly Lys Cys Lys 65 70 75 80
Glu Lys Gly He Arg Val Thr Asn Thr Pro Asp Val Leu Thr Glu Asp 85 90 95
Val Ala Asp Leu Ala He Gly Leu He Leu Ala Leu Leu Arg Arg Leu
100 105 110
Cys Glu Cys Asp Arg Tyr Val Arg Ser Gly Lys Trp Lys Gin Gly Glu 115 120 125 Phe Gin Leu Thr Thr Lys Phe Ser Gly Lys Ser Val Gly He He Gly 130 135 140
Leu Gly Arg He Gly Thr Ala He Ala Lys Arg Ala Glu Ala Phe Ser 145 150 155 160
Cys Pro He Asn Tyr Tyr Ser Arg Thr He Lys Pro Asp Val Ala Tyr 165 170 175
Lys Tyr Tyr Pro Thr Val Val Asp Leu Ala Gin Asn Ser Asp He Leu
180 185 190
Val Val Ala Cys Pro Leu Thr Glu Gin Thr Arg His He Val Asp Arg 195 200 205 Gin Val Met Asp Ala Leu Gly Ala Lys Gly Val Leu He Asn He Gly 210 215 220
Arg Gly Pro His Val Asp Glu Gin Glu Leu He Lys Ala Leu Thr Glu 225 230 235 240
Gly Arg Leu Gly Gly Ala Ala Leu Asp Val Phe Glu Gin Glu Pro His
245 250 255
Val Pro Glu Glu Leu Phe Gly Leu Glu Asn Val Val Leu Leu Pro His
260 265 270
Val Gly Ser Gly Thr Val Glu Thr Arg Asn Ala Met Ala Asp Leu Val
275 280 285
Val Gly Asn Leu Glu Ala His Phe Ser Gly Lys Ser Leu Leu Thr Pro
290 295 300
Val Val 305 (2) INFORMATION FOR SEQ ID NO: 364;
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 555 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic) (ix) FEATURE :
(A) NAME/KEY:
(B) LOCATION: 1..555
(D) OTHER INFORMATION: / Ceres Seq. ID 2025372 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 364: aaaactcact ttcacttgca caaagataag gaaaccatgt ctgtgtcagc gatctttggt 60 accggaatcg tcaccgttgc tgcttctccg gttctccgcc aatttcaagt tccaaaattg 120 ggtaatggag gaggattagg gatggtgata gagtgttcgt cgaggccaca gaagaaatcg 180 acggctcatc acaggaagac gaggccgaag aagactcagc cttgggacat taagagaaag 240 cctactgttt acgctcctct tcctcctctt ccggcggaat ggagtccgtt cactctcgct 300 tctgacgacg gtggtgctgc cactgctgcg ggagatttgg tttcaggcgc tgcctagttg 360 gtatgagtta tctgctgatt tggttgtaat ctagtttgag aacttttgtt gttgtttact 420 gtgttttcag ttttctgatg tttgttgttg ggtttgtttg tgtttgattg gtgaatgaat 480 ggaccaaatt tgcgatttat aaagcttcaa cctttctcct ctgtttttga gtttaaaggt 540 ctcaacttta tagtt
(2) INFORMATION FOR SEQ ID NO: 365: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 118 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY peptide
(B) LOCATION 1..118
(D) OTHER INFORMATION: / Ceres Seq. ID 2025373
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 365:
Lys Thr His Phe His Leu His Lys Asp Lys Glu Thr Met Ser Val Ser
1 10 15 Ala He Phe Gly Thr Gly He Val Thr Val Ala Ala Ser Pro Val Leu
20 25 30
Arg Gin Phe Gin Val Pro Lys Leu Gly Asn Gly Gly Gly Leu Gly Met
35 40 45
Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser Thr Ala His His
50 55 60
Arg Lys Thr Arg Pro Lys Lys Thr Gin Pro Trp Asp He Lys Arg Lys 65 70 75 80
Pro Thr Val Tyr Ala Pro Leu Pro Pro Leu Pro Ala Glu Trp Ser Pro
85 90 95
Phe Thr Leu Ala Ser Asp Asp Gly Gly Ala Ala Thr Ala Ala Gly Asp
100 105 110
Leu Val Ser Gly Ala Ala
115 (2) INFORMATION FOR SEQ ID NO: 366: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 106 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..106 (D) OTHER INFORMATION: / Ceres Seq. ID 2025374
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:366: Met Ser Val Ser Ala He Phe Gly Thr Gly He Val Thr Val Ala Ala 1 5 10 15
Ser Pro Val Leu Arg Gin Phe Gin Val Pro Lys Leu Gly Asn Gly Gly 20 25 30
Gly Leu Gly Met Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser
35 40 45
Thr Ala His His Arg Lys Thr Arg Pro Lys Lys Thr Gin Pro Trp Asp 50 55 60 He Lys Arg Lys Pro Thr Val Tyr Ala Pro Leu Pro Pro Leu Pro Ala 65 70 75 80
Glu Trp Ser Pro Phe Thr Leu Ala Ser Asp Asp Gly Gly Ala Ala Thr
85 90 95
Ala Ala Gly Asp Leu Val Ser Gly Ala Ala 100 105
(2) INFORMATION FOR SEQ ID NO: 367: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 71 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..71
(D) OTHER INFORMATION: / Ceres Seq. ID 2025375 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 367: Met Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser Thr Ala His 1 5 10 15 His Arg Lys Thr Arg Pro Lys Lys Thr Gin Pro Trp Asp He Lys Arg
20 25 30
Lys Pro Thr Val Tyr Ala Pro Leu Pro Pro Leu Pro Ala Glu Trp Ser
35 40 45
Pro Phe Thr Leu Ala Ser Asp Asp Gly Gly Ala Ala Thr Ala Ala Gly 50 55 60
Asp Leu Val Ser Gly Ala Ala 65 70
(2) INFORMATION FOR SEQ ID NO: 368: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 631 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..631
(D) OTHER INFORMATION: / Ceres Seq. ID 2025471 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 368: atgtcgcgaa agttcctaaa accgccacgt gtcagtcact tatccaacag taatccaatt 60 attcgtcaag cctccggttt attaccgtct aaaccgaaaa gaaaaaactc tcttcggaat 120 ctgaaaagcc ataaatcagc agaaaaaaat cttaaggatc ggaaatttta taatcggatg 180 aatagagtga ttagtcagtt ttccggtaag ttgatgaagg agaagagtgt taccggtgta 240 agcggcggag atacgacttt aagatctgcc gtcaaagaat cggtctcgtc tccacagagt 300 gcgtcgtcgt cgtcgtcggt gaggaggctt aaaggagatc tggaatcgag tcgatttggt 360 gcggcggcga gtgagaggct gaggcaagcg gaggaatctt tgaggacggt gatgtttctg 420 agctgttggg gatcttgtta gatctggttg agaaaataat agatgagaaa acgaaaccaa 480 aacgtttctg tttgtgtttt tgagttttgg atttttgttt tctctgtgaa tagttttttt 540 tttttttttc gttttctttg tactttgtgt tttatgtaaa tcatgtataa aatgaaaagt 600 aaatcaatga agataatggt ttgtcttcac c (2 INFORMATION FOR SEQ ID NO: 369: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 146 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..146
(D) OTHER INFORMATION: : / Ceres Seq. ID 2025472
(xi) SEQUENCE DESCRIPTION: SEQ . ED NO:369:
Met Ser Arg Lys Phe Leu Lys Pro Pro Arg Val Ser His Leu Ser Asn
5 10 15
Ser Asn Pro He He Arg Gin Ala Ser Gly Leu Leu Pro Ser Lys Pro 20 25 30
Lys Arg Lys Asn Ser Leu Arg Asn Leu Lys Ser His Lys Ser Ala Glu 35 40 45
Lys Asn Leu Lys Asp Arg Lys Phe Tyr Asn Arg Met Asn Arg Val He 50 55 60
Ser Gin Phe Ser Gly Lys Leu Met Lys Glu Lys Ser Val Thr Gly Val
65 70 75 80
Ser Gly Gly Asp Thr Thr Leu Arg Ser Ala Val Lys Glu Ser Val Ser 85 90 95
Ser Pro Gin Ser Ala Ser Ser Ser Ser Ser Val Arg Arg Leu Lys Gly 100 105 110
Asp Leu Glu Ser Ser Arg Phe Gly Ala Ala Ala Ser Glu Arg Leu Arg 115 120 125
Gin Ala Glu Glu Ser Leu Arg Thr Val Met Phe Leu Ser Cys Trp Gly 130 135 140
Ser Cys
145
(2) INFORMATION FOR SEQ ID NO:370:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 87 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..87 (D) OTHER INFORMATION: / Ceres Seq. ID 2025473
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 370:
Met Asn Arg Val He Ser Gin Phe Ser Gly Lys Leu Met Lys Glu Lys
1 5 10 15
Ser Val Thr Gly Val Ser Gly Gly Asp Thr Thr Leu Arg Ser Ala Val 20 25 30
Lys Glu Ser Val Ser Ser Pro Gin Ser Ala Ser Ser Ser Ser Ser Val 35 40 45
Arg Arg Leu Lys Gly Asp Leu Glu Ser Ser Arg Phe Gly Ala Ala Ala 50 55 60
Ser Glu Arg Leu Arg Gin Ala Glu Glu Ser Leu Arg Thr Val Met Phe 65 70 75 80 Leu Ser Cys Trp Gly Ser Cys
85 (2) INFORMATION FOR SEQ ID NO: 371: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 75 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..75
(D) OTHER INFORMATION: / Ceres Seq. ID 2025474 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 371: Met Lys Glu Lys Ser Val Thr Gly Val Ser Gly Gly Asp Thr Thr Leu 1 5 10 15
Arg Ser Ala Val Lys Glu Ser Val Ser Ser Pro Gin Ser Ala Ser Ser
20 25 30
Ser Ser Ser Val Arg Arg Leu Lys Gly Asp Leu Glu Ser Ser Arg Phe 35 40 45
Gly Ala Ala Ala Ser Glu Arg Leu Arg Gin Ala Glu Glu Ser Leu Arg
50 55 60
Thr Val Met Phe Leu Ser Cys Trp Gly Ser Cys 65 70 75 (2) INFORMATION FOR SEQ ID NO: 372: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 2029 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..2029 (D) OTHER INFORMATION: / Ceres Seq. ID 2025475
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 372: atgggtaaga gttggttttc agctgtgaag aaagcattaa gcccagaacc aaaacaaaag 60 aaagagcaga agccacataa gtccaagaaa tggtttggta aatccaagaa gctagatgtt 120 actaattctg gtgcagcata ttctcctcgt actgtcaaag acgcgaaact aaaggagatt 180 gaggagcaac agagcagaca tgcttactct gtggctattg caactgctgc agctgcagag 240 gcagccgttg cagctgctca agctgctgct gaagttgttc gtctctctgc attatcacgg 300 ttccccggga aatcaatgga agagatcgcc gctatcaaga ttcagacagc atttagagga 360 tatatggcaa gaagagcatt gcgtgcgttg agaggtcttg tgaggctaaa atctttagtc 420 caggggaaat gtgtgagacg tcaagccaca tctacattgc aaagcatgca aacactagct 480 agagtacaat atcagattcg tgagagaagg ctccgattgt ctgaggataa acaggcttta 540 acacgacagc tccaacaaaa acacaataaa gactttgata agactggaga aaattggaat 600 gatagtacat tgtcgcggga gaaagttgaa gcaaacatgt tgaacaagca agtagcaaca 660 atgagaagag aaaaagcgct tgcatatgca ttcagtcacc agaatacatg gaaaaactca 720 actaaaatgg gttctcaaac attcatggac cctaacaatc cgcattgggg ttggagttgg 780 ctagaacgtt ggatggctgc tcgaccaaac gaaaaccact cactcacacc agataatgct 840 gaaaaagact cttctgctag gagtgtagca agccgtgcca tgtctgagat gattccacga 900 ggcaaaaacc tttcaccaag aggaaagaca ccaaacagtc gaagagggtc aagcccgaga 960 gtgaggcaag tcccaagtga agactcaaac agcattgtga gtttccaatc agaacaacct 1020 tgcaatcgta ggcatagcac ttgtggatca attccatcaa ctagagacga tgaaagcttc 1080 accagtagtt tctctcagtc agttccaggc tacatggcac ctacacaagc cgccaaagca 1140 agagctcgat tctcaaacct tagtcctcta agctcagaga agacagcgaa aaaacggctt 1200 tccttctcgg gatctcctaa gactgtaaga cggttttcag tagggattct agggctttcc 1260 ttcattggtc agatcagacg acgttttaca tcttcttctt cttcctcttc gatattcgtc 1320 agtgtgtgta ttttggggaa aactttgtga gcaaagagcg agaaaatgag cggaccggta 1380 agaaaatcgc ggatgtggct ttcaaagctt cgaggactat cgattgggat ggtatggcta 1440 aggtccttgt cacagatgag gctcgtagag agttctctaa ccttcgtcgt gctttcgatg 1500 aggttaacac acagctccag accaaattta gtcaggaacc tgaacccata gattgggatt 1560 actataggaa gggtattgga gctggcattg ttgacaagta caaggaagct tatgacagca 1620 ttgagattcc aaagtacgtt gacaaagtta ctcctgaata caagccaaag tttgatgctt 1680 tgttggtgga actgaaagaa gcagaacaga aatcgctcaa ggagtctgaa cggttggaga 1740 aagaaattgc tgatgtccaa gagatcagca aaaagctcag caccatgact gcagatgagt 1800 actttgagaa gcacccggaa ctcaaaaaga agtttgatga cgaaatccgt aatgacaact 1860 ggggatactg atcatgtttc tccatctccg gcttggaaag aaaactctct ttctctttct 1920 ctgttctctt actgtgattt tgtgagccaa tcataacaat aataagtaca ccattcactt 1980 aagcagtgtt gagatcttca ttccaaggaa gataaacgca tttggtttt (2) INFORMATION FOR SEQ ID NO: 373: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 449 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..449
(D) OTHER INFORMATION: / Ceres Seq. ID 2025476
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:373~:
Met Gly Lys Ser Trp Phe Ser Ala Val Lys Lys Ala Leu Ser Pro Glu
1 5 10 15
Pro Lys Gin Lys Lys Glu Gin Lys Pro His Lys Ser Lys Lys Trp Phe 20 25 30
Gly Lys Ser Lys Lys Leu Asp Val Thr Asn Ser Gly Ala Ala Tyr Ser 35 40 45
Pro Arg Thr Val Lys Asp Ala Lys Leu Lys Glu He Glu Glu Gin Gin
50 55 60
Ser Arg His Ala Tyr Ser Val Ala He Ala Thr Ala Ala Ala Ala Glu
65 70 75 80
Ala Ala Val Ala Ala Ala Gin Ala Ala Ala Glu Val Val Arg Leu Ser 85 90 95
Ala Leu Ser Arg Phe Pro Gly Lys Ser Met Glu Glu He Ala Ala He 100 105 110
Lys He Gin Thr Ala Phe Arg Gly Tyr Met Ala Arg Arg Ala Leu Arg 115 120 125
Ala Leu Arg Gly Leu Val Arg Leu Lys Ser Leu Val Gin Gly Lys Cys 130 135 140
Val Arg Arg Gin Ala Thr Ser Thr Leu Gin Ser Met Gin Thr Leu Ala
145 150 155 160
Arg Val Gin Tyr Gin He Arg Glu Arg Arg Leu Arg Leu Ser Glu Asp 165 170 175
Lys Gin Ala Leu Thr Arg Gin Leu Gin Gin Lys His Asn Lys Asp Phe 180 185 190
Asp Lys Thr Gly Glu Asn Trp Asn Asp Ser Thr Leu Ser Arg Glu Lys 195 200 205
Val Glu Ala Asn Met Leu Asn Lys Gin Val Ala Thr Met Arg Arg Glu 210 215 220
Lys Ala Leu Ala Tyr Ala Phe Ser His Gin Asn Thr Trp Lys Asn Ser
225 230 235 240
Thr Lys Met Gly Ser Gin Thr Phe Met Asp Pro Asn Asn Pro His Trp 245 250 255
Gly Trp Ser Trp Leu Glu Arg Trp Met Ala Ala Arg Pro Asn Glu Asn 260 265 270
His Ser Leu Thr Pro Asp Asn Ala Glu Lys Asp Ser Ser Ala Arg Ser 275 280 285
Val Ala Ser A_rg Ala Met Ser Glu Met He Pro Arg Gly Lys Asn Leu 290 295 300
Ser Pro Arg Gly Lys Thr Pro Asn Ser Arg Arg Gly Ser Ser Pro Arg
305 310 315 320
Val Arg Gin Val Pro Ser Glu Asp Ser Asn Ser He Val Ser Phe Gin 325 330 335 Ser Glu Gin Pro Cys Asn Arg Arg His Ser Thr Cys Gly Ser He Pro
340 345 350
Ser Thr Arg Asp Asp Glu Ser Phe Thr Ser Ser Phe Ser Gin Ser Val 355 360 365 Pro Gly Tyr Met Ala Pro Thr Gin Ala Ala Lys Ala Arg Ala Arg Phe 370 375 380
Ser Asn Leu Ser Pro Leu Ser Ser Glu Lys Thr Ala Lys Lys Arg Leu 385 390 395 400
Ser Phe Ser Gly Ser Pro Lys Thr Val Arg Arg Phe Ser Val Gly He 405 410 415
Leu Gly Leu Ser Phe He Gly Gin He Arg Arg Arg Phe Thr Ser Ser
420 425 430
Ser Ser Ser Ser Ser He Phe Val Ser Val Cys He Leu Gly Lys Thr 435 440 445 Leu
(2) INFORMATION FOR SEQ ID NO: 374: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 344 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..344
(D) OTHER INFORMATION: / Ceres Seq. ID 2025477 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 374: Met Glu Glu He Ala Ala He Lys He Gin Thr Ala Phe Arg Gly Tyr 1 5 10 15
Met Ala Arg Arg Ala Leu Arg Ala Leu Arg Gly Leu Val Arg Leu Lys
20 25 30
Ser Leu Val Gin Gly Lys Cys Val Arg Arg Gin Ala Thr Ser Thr Leu 35 40 45 Gin Ser Met Gin Thr Leu Ala Arg Val Gin Tyr Gin He Arg Glu Arg 50 55 60
Arg Leu Arg Leu Ser Glu Asp Lys Gin Ala Leu Thr Arg Gin Leu Gin 65 70 75 80
Gin Lys His Asn Lys Asp Phe Asp Lys Thr Gly Glu Asn Trp Asn Asp 85 90 95
Ser Thr Leu Ser Arg Glu Lys Val Glu Ala Asn Met Leu Asn Lys Gin
100 105 110
Val Ala Thr Met Arg Arg Glu Lys Ala Leu Ala Tyr Ala Phe Ser His 115 120 125 Gin Asn Thr Trp Lys Asn Ser Thr Lys Met Gly Ser Gin Thr Phe Met 130 135 140
Asp Pro Asn Asn Pro His Trp Gly Trp Ser Trp Leu Glu Arg Trp Met 145 150 155 160
Ala Ala Arg Pro Asn Glu Asn His Ser Leu Thr Pro Asp Asn Ala Glu " 165 170 175
Lys Asp Ser Ser Ala Arg Ser Val Ala Ser Arg Ala Met Ser Glu Met
180 185 190
He Pro Arg Gly Lys Asn Leu Ser Pro Arg Gly Lys Thr Pro Asn Ser 195 200 205 Arg Arg Gly Ser Ser Pro Arg Val Arg Gin Val Pro Ser Glu Asp Ser 210 215 220
Asn Ser He Val Ser Phe Gin Ser Glu Gin Pro Cys Asn Arg Arg His 225 230 235 240
Ser Thr Cys Gly Ser He Pro Ser Thr Arg Asp Asp Glu Ser Phe Thr 245 250 255
Ser Ser Phe Ser Gin Ser Val Pro Gly Tyr Met Ala Pro Thr Gin Ala 260 265 270 Ala Lys Ala Arg Ala Arg Phe Ser Asn Leu Ser Pro Leu Ser Ser Glu
275 280 285
Lys Thr Ala Lys Lys Arg Leu Ser Phe Ser Gly Ser Pro Lys Thr Val
290 295 300 Arg Arg Phe Ser Val Gly He Leu Gly Leu Ser Phe He Gly Gin He
305 310 315 320
A.rg A.rg Arg Phe Thr Ser Ser Ser Ser Ser Ser Ser He Phe Val Ser
325 330 335
Val Cys He Leu Gly Lys Thr Leu 340
(2) INFORMATION FOR SEQ ID NO: 375: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 328 amino acids
(B) TYPE: ammo acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..328
(D) OTHER INFORMATION: / Ceres Seq. ID 2025478 xi) SEQUENCE DESCRIPTION: SEQ ID NO:375: Met Ala Arg A.rg Ala Leu Arg Ala Leu Arg Gly Leu Val Arg Leu Lys 1 5 10 15 Ser Leu Val Gin Gly Lys Cys Val Arg Arg Gin Ala Thr Ser Thr Leu
20 25 30
Gin Ser Met Gin Thr Leu Ala Arg Val Gin Tyr Gin He Arg Glu Arg
35 40 45
Arg Leu Arg Leu Ser Glu Asp Lys Gin Ala Leu Thr Arg Gin Leu Gin 50 ' 55 60
Gin Lys His Asn Lys Asp Phe Asp Lys Thr Gly Glu Asn Trp Asn Asp 65 ' 70 75 80
Ser Thr Leu Ser Arg Glu Lys Val Glu Ala Asn Met Leu Asn Lys Gin 85 90 95 Val Ala Thr Met Arg Arg Glu Lys Ala Leu Ala Tyr Ala Phe Ser His
100 105 110
Gin Asn Thr Trp Lys Asn Ser Thr Lys Met Gly Ser Gin Thr Phe Met
115 120 125
Asp Pro Asn Asn Pro His Trp Gly Trp Ser Trp Leu Glu Arg Trp Met 130 135 " 140
Ala Ala Arg Pro Asn Glu Asn His Ser Leu Thr Pro Asp Asn Ala Glu
145 150 155 160
Lys Asp Ser Ser Ala Arg Ser Val Ala Ser Arg Ala Met Ser Glu Met
165 170 175 He Pro Arg Gly Lys Asn Leu Ser Pro Arg Gly Lys Thr Pro Asn Ser
180 185 190
Arg A.rg Gly Ser Ser Pro Arg Val Arg Gin Val Pro Ser Glu Asp Ser
195 200 205
Asn Ser He Val Ser Phe Gin Ser Glu Gin Pro Cys Asn Arg Arg His 210 215 220
Ser Thr Cys Gly Ser He Pro Ser Thr Arg Asp Asp Glu Ser Phe Thr
225 230 235 240
Ser Ser Phe Ser Gin Ser Val Pro Gly Tyr Met Ala Pro Thr Gin Ala
245 250 255 Ala Lys Ala Arg Ala Arg Phe Ser Asn Leu Ser Pro Leu Ser Ser Glu
260 265 270
Lys Thr Ala Lys Lys Arg Leu Ser Phe Ser Gly Ser Pro Lys Thr Val
275 280 285
Arg Arg Phe Ser Val Gly He Leu Gly Leu Ser Phe He Gly Gin He ' 290 295 300
Arg Arg Arg Phe Thr Ser Ser Ser Ser Ser Ser Ser He Phe Val Ser 305 310 315 320 Val Cys He Leu Gly Lys Thr Leu
325 (2) INFORMATION FOR SEQ ID NO: 376: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 678 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..678
(D) OTHER INFORMATION: / Ceres Seq. ID 2025524 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:376: gattttttag ggtttcaagt gaaaagagta atagcgcggc ggagccatgg ttctcaagac 60 tgagctttgc cgattcagtg gccagaaaat ttaccctggt agagggatca gatttatccg 120 atcggactct caggtgtttt tgtttctcaa ctccaaatgt aagaggtatt tccacaacaa 180 gttgaagcca tctaagcttt gctggactgc tatgtaccga aagcagcaca agaaggacgc 240 agcacaagag gctgtgaaga gaaggagacg tgcaactaag aagccttact caaggtcgat 300 tgtcggtgct actttggagg ttattcagaa gaagcgagca gagaagcctg aagttcgtga 360 tgccgctaga gaagctgccc tacgtgagat caaggagaga atcaagaaga ccaaggacga 420 gaagaaggca aagaaggtcg agtatgcatc aaagcaacag aagtcacaag tgaagggaaa 480 tatccccaag agtgctgcac ccaaggctgc taagatgggt ggtggtggag gcagacgttg 540 aatggagcta tagagtagcc cactcttctc tcttcactta tctttctttc ttgttttgac 600 attgttttgt tttgtcagcc attttttagt tttgcaccag atctaatata ttcagtttat 660 gaaaactttt tgtttggc (2) INFORMATION FOR SEQ ID NO: 377: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 164 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..164
(D) OTHER INFORMATION: / Ceres Seq. ID 2025525 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 377: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 15
Pro Gly Arg Gly He Arg Phe He Arg Ser Asp Ser Gin Val Phe Leu
20 25 30
Phe Leu Asn Ser Lys Cys Lys Arg Tyr Phe His Asn Lys Leu Lys Pro 35 40 45 Ser Lys Leu Cys Trp Thr Ala Met Tyr Arg Lys Gin His Lys Lys Asp 50 55 60
Ala Ala Gin Glu Ala Val Lys Arg Arg Arg Arg Ala Thr Lys Lys Pro 65 70 75 ' 80
Tyr Ser Arg Ser He Val Gly Ala Thr Leu Glu Val He Gin Lys Lys 85 90 95
Arg Ala Glu Lys Pro Glu Val Arg Asp Ala Ala Arg Glu Ala Ala Leu
100 105 110
Arg Glu He Lys Glu Arg He Lys Lys Thr Lys Asp Glu Lys Lys Ala 115 120 125 Lys Lys Val Glu Tyr Ala Ser Lys Gin Gin Lys Ser Gin Val Lys Gly 130 135 140
Asn He Pro Lys Ser Ala Ala Pro Lys Ala Ala Lys Met Gly Gly Gly 145 150 155 160
Gly Gly Arg Arg
(2) INFORMATION FOR SEQ ID NO: 378: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 109 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..109
(D) OTHER INFORMATION: / Ceres Seq. ID 2025526 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 378:
Met Tyr Arg Lys Gin His Lys Lys Asp Ala Ala Gin Glu Ala Val Lys 1 5 10 15
Arg Arg Arg Arg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly 20 25 30 Ala Thr Leu Glu Val He Gin Lys Lys Arg Ala Glu Lys Pro Glu Val 35 40 45
Arg Asp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu Arg He
50 55 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Val Glu Tyr Ala Ser 65 70 75 80
Lys Gin Gin Lys Ser Gin Val Lys Gly Asn He Pro Lys Ser Ala Ala
85 90 95
Pro Lys Ala Ala Lys Met Gly Gly Gly Gly Gly Arg Arg 100 105 (2) INFORMATION FOR SEQ ID NO: 379: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1623 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1623 (D) OTHER INFORMATION: / Ceres Seq. ID 2025544
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:379: atgggcattt ctaagatgat tcttctgaaa ttcacatatg ttgtttcttt ctggattact 60 tgcgtgatct tcaaaatgtc aagaacgata aaacgagctt tgttgggctc attcatcttc 120 attcttgctt ccgctagtgt tgtggtagcc gccattgtag gagccatcga aggtcacacc 180 actgacatcg gatttcttca aggtagtgtg cttggagtgg tggctggagt tatcactgcg 240 gtccaactct ttggaccggt gctacatagt gatcaacctt tgtctaaggt ggctttactc 300 aggagagtag tgaatgggaa agccattatg ggattggtta gaccttttgt tctcaaagca 360 tatcaatggc aaataatagc attggataca agttacatgg agagttcaaa cttatacgat 420 ttcaatcatg aaaaaaaggg actatcgaag agctctattc agaacatccc gatgttctac 480 aaccgttcag aacatcaaac aaaatcgagt tgctcgattt gcttacagga ttgggaagaa 540 ggggaagtag gaagaaagct agcaagatgt ggccacacat ttcatatgaa ttgcatagat 600 gagtggttgc ttagacaaga aacttgcccc atttgaagaa gacaaaagaa gaagcacgag 660 aatcatctgc ttaaaatcca atcgcatcga ctcagtcttc ttcttcttct tcacctacct 720 ttctctctct ctctcgtggt ccattcgcta ttctatactt cttgtcggcg ccggagagag 780 tgagatgact tggtcggttt tcagatccat aaatactcca acactcgacc tctccaccgc 840 acttcgctcc actcgtaccc cattggtcgc tgctggtgtc ggctgcgcaa cattcgctgg 900 tgtttctctc ttcagaatgt cttctagatc tcctcctttc gcttccctct ctgtctctgc 960 ttcttctgtg aagaaggaag ttgtgtctac tgagaaagca ccagctgctt tgggacctta 1020 ctctcaggcc attaaagcca ataatctggt ttttctttca ggtgttcttg gacttatacc 1080 tgagactgga aagtttgttt cggagagcgt cgaagatcag actgagcagg tactcaaaaa 1140 catgggggag atattgaaag ctagtggtgc tgattattcc tcggtggtga agacaacaat 1200 catgttggct gatttggctg acttcaagac agtgaacgag atatatgcca aatacttccc 1260 agctccttct ccagcacgat cgacgtatca agttgcagct ttgcctctaa acgccaagat 1320 cgagattgaa tgtattgcaa cactctagaa cactcaaatc aatctctacg aagggtattt 1380 tggtccggaa gatgtcaaaa caaataagag aaacaatggt ttttggggct taacccatat 1440 ttaacctact tttcattttg ctgcactacg aaaaatgttg cggattatca accattaggt 1500 tggttacaaa tcaaaagcct ctaatcaaga ataagttatt tagtgtcttg tccaccctca 1560 tttgctgttg acgtatatgt attgattgta tacattattt tatttgagtg aaaccattat 1620 get
(2) INFORMATION FOR SEQ ID NO: 380: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 249 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..249
(D) OTHER INFORMATION: / Ceres Seq. ID 2025545 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 380: Met Ser Gly Cys Leu Asp Lys Lys Leu Ala Pro Phe Glu Glu Asp Lys 1 5 10 15
Arg Arg Ser Thr Arg He He Cys Leu Lys Ser Asn Arg He Asp Ser
20 25 30
Val Phe Phe Phe Phe Phe Thr Tyr Leu Ser Leu Ser Leu Ser Trp Ser 35 40 45
He Arg Tyr Ser He Leu Leu Val Gly Ala Gly Glu Ser Glu Met Thr
50 " 55 60
Trp Ser Val Phe Arg Ser He Asn Thr Pro Thr Leu Asp Leu Ser Thr 65 70 75 80 Ala Leu Arg Ser Thr Arg Thr Pro Leu Val Ala Ala Gly Val Gly Cys
85 90 95
Ala Thr Phe Ala Gly Val Ser Leu Phe Arg Met Ser Ser Arg Ser Pro
100 105 110
Pro Phe Ala Ser Leu Ser Val Ser Ala Ser Ser Val Lys Lys Glu Val 115 120 125
Val Ser Thr Glu Lys Ala Pro Ala Ala Leu Gly Pro Tyr Ser Gin Ala
130 135 140
He Lys Ala Asn Asn Leu Val Phe Leu Ser Gly Val Leu Gly Leu He 145 150 155 160 Pro Glu Thr Gly Lys Phe Val Ser Glu Ser Val Glu Asp Gin Thr Glu
165 170 175
Gin Val Leu Lys Asn Met Gly Glu He Leu Lys Ala Ser Gly Ala Asp
180 185 190
Tyr Ser Ser Val Val Lys Thr Thr He Met Leu Ala Asp Leu Ala Asp 195 200 205
Phe Lys Thr Val Asn Glu He Tyr Ala Lys Tyr Phe Pro Ala Pro Ser
210 215 220
Pro Ala Arg Ser Thr Tyr Gin Val Ala Ala Leu Pro Leu Asn Ala Lys 225 " 230 235 240 He Glu He Glu Cys He Ala Thr Leu
245 (2) INFORMATION FOR SEQ ID NO: 381: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 211 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..211
(D) OTHER INFORMATION: / Ceres Seq. ID 2025546 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 381: Met Gly He Ser Lys Met He Leu Leu Lys Phe Thr Tyr Val Val Ser 1 5 10 15
Phe Trp He Thr Cys Val He Phe Lys Met Ser Arg Thr He Lys Arg 20 25 30 Ala Leu Leu Gly Ser Phe He Phe He Leu Ala Ser Ala Ser Val Val
35 40 45
Val Ala Ala He Val Gly Ala He Glu Gly His Thr Thr Asp He Gly 50 55 60 Phe Leu Gin Gly Ser Val Leu Gly Val Val Ala Gly Val He Thr Ala 65 70 75 80
Val Gin Leu Phe Gly Pro Val Leu His Ser Asp Gin Pro Leu Ser Lys
85 90 95
Val Ala Leu Leu Arg Arg Val Val Asn Gly Lys Ala He Met Gly Leu 100 ' 105 110
Val Arg Pro Phe Val Leu Lys Ala Tyr Gin Trp Gin He He Ala Leu
115 120 125
Asp Thr Ser Tyr Met Glu Ser Ser Asn Leu Tyr Asp Phe Asn His Glu
130 135 140 Lys Lys Gly Leu Ser Lys Ser Ser He Gin Asn He Pro Met Phe Tyr
145 150 155 160
Asn Arg Ser Glu His Gin Thr Lys Ser Ser Cys Ser He Cys Leu Gin
165 170 175
Asp Trp Glu Glu Gly Glu Val Gly Arg Lys Leu Ala Arg Cys Gly His 180 185 190
Thr Phe His Met A.sn Cys He Asp Glu Trp Leu Leu Arg Gin Glu Thr
195 200 2C5
Cys Pro He 210 (2) INFORMATION FOR SEQ ID NO:382: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 206 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..20o (D) OTHER INFORMATION: / Ceres Seq. ID 2025547
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 382: Met He Leu Leu Lys Phe Thr Tyr Val Val Ser Phe Trp He Thr Cys 1 5 10 15
Val He Phe Lys Met Ser Arg Thr He Lys Arg Ala Leu Leu Gly Ser 20 25 30
Phe He Phe He Leu Ala Ser Ala Ser ^al Val Val Ala Ala He Val
35 40 45
Gly Ala He Glu Gly His Thr Thr Asp He Gly Phe Leu Gin Gly Ser
50 55 60 Val Leu Gly Val Val Ala Gly Val He Thr Ala Val Gin Leu Phe Gly
65 70 75 80~
Pro Val Leu His Ser Asp Gin Pro Leu Ser Lys Val Ala Leu Leu Arg
85 90 95
Arg Val Val Asn Gly Lys Ala He Met Gly Leu Val Arg Pro Phe Val 100 105 110
Leu Lys Ala Tyr Gin Trp Gin He He Ala Leu Asp Thr Ser Tyr Met
115 120 125
Glu Ser Ser Asn Leu Tyr Asp Phe Asn His Glu Lys Lys Gly Leu Ser
130 135 140 Lys Ser Ser He Gin Asn He Pro Met Phe Tyr Asn Arg Ser Glu His
145 150 155 160
Gin Thr Lys Ser Ser Cys Ser He Cys Leu Gin Asp Trp Glu Glu Gly
165 170 175
Glu Val Gly Arg Lys Leu Ala Arg Cys Gly His Thr Phe His Met Asn 180 185 190
Cys He Asp Glu Trp Leu Leu Arg Gin Glu Thr Cys Pro He 195 200 205 (2) INFORMATION FOR SEQ ID NO: 383:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 542 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
((BB)) LLOOCCAATTIIOONN:: 1..542
(D) OTHER INFORMATION: / Ceres Seq. ID 2026207
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 38 5. tcaccaaaat ctcttctctc tcttccattg tcttcctcta atggaaccaa ccgagaaatc 60 tatgttacta gaaactacta gtaccacgaa gatggagacc aaatacgaag atatgttacc 120 agttatggcg gagaagatgg atgttgaaga gtttgtatca gagttatgca aaggtttcag 180 tttgcttgcg gatccagaga gacatctcat cacagctgag tctctaagac gaaactcagg 240 gatacttgga attgaaggta tgagcaagga agatgctcaa ggaatggtta gagaaggaga 300 cctcgatgga gatggtgctc ttaaccaaac cgaattctgc gttctcatgg ttcggttaag 360 ccctgagatg atggaagacg ccgaaacttg gttggagaaa gcactcaccc aagaactatg 420 taatcacaat ctctcttcta tgccttgaat gatcgtcctc ctttcttgtg tattctcttt 480 ttacttctac aaaacctata aatgtttctg aatataaaat gaagtaatga tttcttgatc 540 cc
(2) INFORMATION FOR SEQ ID NO: 384: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH : 148 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..148
(D) OTHER INFORMATION: / Ceres Seq. ID 202620. (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 384: His Gin Asn Leu Phe Ser Leu Phe His Cys Leu Pro Leu Met Glu Pro 1 5 10 15
Thr Glu Lys Ser Met Leu Leu Glu Thr Thr Ser Thr Thr Lys Met Glu
20 25 30
Thr Lys Tyr Glu Asp Met Leu Pro Val Met Ala Glu Lys Met Asp Val 35 40 45
Glu Glu Phe Val Ser Glu Leu Cys Lys Gly Phe Ser Leu Leu Ala Asp
50 55 60
Pro Glu Arg His Leu He Thr Ala Glu Ser Leu Arg Arg Asn Ser Gly 65 70 75 80 He Leu Gly He Glu Gly Met Ser Lys Glu Asp Ala Gin Gly Met Val
85 90 95
Arg Glu Gly Asp Leu Asp Gly Asp Gly Ala Leu Asn Gin Thr Glu Phe 100 105 110
Cys Val Leu Met Val Arg Leu Ser Pro Glu Met Met Glu Asp Ala Glu 115 120 125
Thr Trp Leu Glu Lys Ala Leu Thr Gin Glu Leu Cys Asn His Asn Leu
130 135 140
Ser Ser Met Pro 145 (2) INFORMATION FOR SEQ ID NO: 385: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 135 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..135
(D) OTHER INFORMATION: / Ceres Seq. ID 2026209 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 385: Met Glu Pro Thr Glu Lys Ser Met Leu Leu Glu Thr Thr Ser Thr Thr 1 5 10 15
Lys Met Glu Thr Lys Tyr Glu Asp Met Leu Pro Val Met Ala Glu Lys
20 25 30
Met Asp Val Glu Glu Phe Val Ser Glu Leu Cys Lys Gly Phe Ser Leu 35 40 45
Leu Ala Asp Pro Glu Arg His Leu He Thr Ala Glu Ser Leu Arg Arg
50 55 60
Asn Ser Gly He Leu Gly He Glu Gly Met Ser Lys Glu Asp Ala Gin 65 70 75 80 Gly Met Val Arg Glu Gly Asp Leu Asp Gly Asp Gly Ala Leu Asn Gin
85 90 95
Thr Glu Phe Cys Val Leu Met Val Arg Leu Ser Pro Glu Met Met Glu
100 105 110
Asp Ala Glu Thr Trp Leu Glu Lys Ala Leu Thr Gin Glu Leu Cys Asn 115 120 125
His Asn Leu Ser Ser Met Pro 130 135
(2) INFORMATION FOR SEQ ID NO: 386: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 128 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..128
(D) OTHER INFORMATION: / Ceres Seq. ID 20,, '210 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 386: Met Leu Leu Glu Thr Thr Ser Thr Thr Lys Met Glu Thr Lys Tyr Glu 1 5 10 15
Asp Met Leu Pro Val Met Ala Glu Lys Met Asp Val Glu Glu Phe Val
20 25 30
Ser Glu Leu Cys Lys Gly Phe Ser Leu Leu Ala Asp Pro Glu Arg His 35 40 45
Leu He Thr Ala Glu Ser Leu Arg Arg Asn Ser Gly He Leu Gly He
50 55 60
Glu Gly Met Ser Lys Glu Asp Ala Gin Gly Met Val Arg Glu Gly Asp 65 70 75 80 Leu Asp Gly Asp Gly Ala Leu Asn Gin Thr Glu Phe Cys Val Leu Met
85 90 95
Val Arg Leu Ser Pro Glu Met Met Glu Asp Ala Glu Thr Trp Leu Glu
100 105 110
Lys Ala Leu Thr Gin Glu Leu Cys Asn His Asn Leu Ser Ser Met Pro 115 120 125
(2) INFORMATION FOR SEQ ID NO: 387: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 552 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..552
(D) OTHER INFORMATION: / Ceres Seq. ID 2026982 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 387: atgaagtata aaaacgtttt tcttaaatta tggatgtctt ctctttatat agtgcccact 60 tcctcattag cattctacag tctgcacact tatcacttct ttcgaaatct ctctctatcc 120 ctctcaaaaa tgaagctctc tgtgcgtttt atctccgctg ctcttctctt gttcatggta 180 ttcattgcca cagggatggg tccagtcacc gtggaggcac gcacgtgtga gtcaaaaagc 240 cataggttca agggtccatg tgtgagcaca cacaactgtg caaacgtgtg ccacaacgaa 300 ggcttcggcg gaggtaaatg ccgtggattc cgtcgtcgtt gctactgcac aagacactgc 360 tgatccatcc attctcatga ctcaaatctt cgatccatcg tcagtgtgtt acttctttct 420 tatctaaatc ttccgtacgg taccatgtcg taccgtacat gagtgttttc tcgaataagt 480 cattggtttg tgtgtttccg gttttaatgt aatgttaaat caattaatgg cttttaatat 540 attgtattat gg
(2) INFORMATION FOR SEQ ID NO: 388:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 120 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
Iii) MOLECULE TYPE: peptide [ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..120
(D) OTHER INFORMATION: / Ceres Seq. I D 2026983 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 388:
Met Lys Tyr Lys Asn Val Phe Leu Lys Leu Trp Met Ser Ser Leu Tyr 1 5 10 15
He Val Pro Thr Ser Ser Leu Ala Phe Tyr Ser Leu His Thr Tyr His
20 25 30
Phe Phe Arg Asn Leu Ser Leu Ser Leu Ser Lys Met Lys Leu Ser Val
35 45
Arg Phe He Ser Ala Ala Leu Leu Leu Phe Met Val Phe He Ala Thr
50 55 60
Gly Met Gly Pro Val Thr Val Glu Ala Arg Thr Cys Glu Ser Lys Ser 65 70 75 80
His Arg Phe Lys Gly Pro Cys Val Ser Thr His A - Cys Ala Asn Val
85 90 95
Cys His Asn Glu Gly Phe Gly Gly Gly Lys Cys Arg Gly Phe Arg Arg
100 105 " 110
Arg Cys Tyr Cys Thr Arg His Cys 115 120
(2! INFORMATION FOR SEQ ID NO: 389:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 109 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..109
(D) OTHER INFORMATION: / Ceres Seq. ID 2026984
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 389:
Met Ser Ser Leu Tyr He Val Pro Thr Ser Ser Leu Ala Phe Tyr Ser 1 10 15
Leu His Thr Tyr His Phe Phe Arg Asn Leu Ser Leu Ser Leu Ser Lys
20 25 30
Met Lys Leu Ser Val Arg Phe He Ser Ala Ala Leu Leu Leu Phe Met
35 40 45
Val Phe He Ala Thr Gly Met Gly Pro Val Thr Val Glu Ala Arg Thr
50 55 60
Cys Glu Ser Lys Ser His Arg Phe Lys Gly Pro Cys Val Ser Thr His 65 70 75 80
Asn Cys Ala Asn Val Cys His Asn Glu Gly Phe Gly Gly Gly Lys Cys 85 90 95 Arg Gly Phe Arg Arg Arg Cys Tyr Cys Thr Arg His Cys
100 105
(2) INFORMATION FOR SEQ ID NO: 390: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 77 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..77
(D) OTHER INFORMATION: / Ceres Seq. ID 2026985 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 390: Met Lys Leu Ser Val Arg Phe He Ser Ala Ala Leu Leu Leu Phe Met 1 5 10 15
Val Phe He Ala Thr Gly Met Gly Pro Val Thr Val Glu Ala Arg Thr
20 25 30
Cys Glu Ser Lys Ser His Arg Phe Lys Gly Pro Cys Val Ser Thr His 35 40 45
Asn Cys Ala Asn Val Cys His Asn Glu Gly Phe Gly Gly Gly Lys Cys
50 55 60
Arg Gly Phe Arg A.rg Arg Cys Tyr Cys Thr A.rg His Cys 65 70 75 (2) INFORMATION FOR SEQ ID NO: 391: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 66 ammo acids
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..66 (D) OTHER INFORMATION: / Ceres Seq. ID 2026986
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 391: Met Asp Val Phe Ser Leu Tyr Ser Ala His Phe Leu He Ser He Leu 1 5 10 15
Gin Ser Ala His Leu Ser Leu Leu Ser Lys Ser Leu Ser He Pro Leu 20 25 30
Lys Asn Glu Ala Leu Cys Ala Phe Tyr Leu Arg Cys Ser Ser Leu Val
35 40 45
His Gly He His Cys His Arg Asp Gly Ser Ser His Arg Gly Gly Thr 50 55 60 His Val 65
(2) INFORMATION FOR SEQ ID NO: 392: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1760 case pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..1760
(D) OTHER INFORMATION: / Ceres Seq. ID 2027300
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 392: ctcgtttcat gagagaaaca aaaaatctta tctttctgac aacggtggtg gtgtgtαatg 60 ttgtcagcca tggcaaagac agctacaacg atctctctct cttttcttct tcttctgtgt 120 ctgtctttaa atagagtctc tttgaaacga agcagctttg tcctgttctg atatccatgg 180 ctttaccttc gtgcttaaag actggagctt taatgtctcc ggccactgga tttaattttt 240 ccggcagtct tatgaagtca gacagcggct tcgccgttcc gacaaagtta cagagtactc 300 gaaaaggtga tcgagagaga ttgagagtcc aagctatttt cagtttccct cctgcgtttc 360 tgacaagaaa cggtcgagct gagaaacaga aacagctcaa acaagaactt cttgaagcca 420 ttgagcctct tgaacgtggt gctacggcct cgcctgatga ccagcttcgg attgatcagt 480 tagcgcgtaa agtggaagca gttaatccca ccaaggagcc tttgaagtct gatttggtca 540 atggaaaatg ggagctcatt tatacaacct ctgcttcgat tttgcaggca aagaaaccaa 600 ggttcttaag atcaataacc aactaccaat ctatcaatgt ggatacactt aaggtgcaaa 660 acatggagac ttggcctttc tataactcgg taactggaga cataaaaccc ctcaattcga 720 agaaggttgc tg gaaactc caagtgttta aaattctcgg atttattcct ataaaagcac 780 ctgatagcgc ccgcggtgaa cttgagatta cctatgtgga cgaggaacta cggttatcaa 840 gagatctttc attcatgtct catαtctggt tccatgacct ttctacattg tttctgttga 900 tttatgaatc ttcaataaca ctacαagtta aaccaattag aagtgagttg gttatggtcc 960 ggtacaaaga tcacaaccgg agaaggattg aagagtggtc aaagcgatgg tcagagttgg 1020 ttggttccgt cgaaacagga agaaagagtc tctcagaaac gacccagcca ctctttaaaa 1080 ctccattgga aaagctttgt cctgttttga tatccatggc tttaccttgg tgcttaaaga 1140 ctggagtttt aacgtctccg gccgccggat ttaatcatcc atcggacagt ggcttcgccg 1200 ttccgacgaa gttactgagt attcgaaaag gtgatcggga aagattgaga atccaagctg 1260 ttttcagctt tcctccaaga aacggtggag ccgagaagcg gaaacagctc aaacatgaac 1320 ttgtcgaagc cattgagcct cttgaacgtg gtgccactgc ctcgcctgat gatcagcttc 1380 tgattgatca gttagcacgt aaggtggaag cagtaaaccc aaccaaggag cctctgaagt 1440 ctgatttgat caatgggaaa tgggagctca tttacacaac atctgctgcg attttgcaag 1500 caaagaaacc aaggttctta agatcgttaa ctaactacca atgtatcaat atggatacac 1560 taaaggtgca aagaatggag acttggcctt tctataactc ggtaactgga gacttgacac 1620 ccctcaactc gaagacggtt gctgtgaaac ttcaagtgtt taaaattctc ggctttattc 1680 cggtaaaagc acctgatggt actgcacgcg gtgaactaga gattacctat gtggacgagg 1740 aactacgcga caaactttga (2) INFORMATION FOR SEQ ID NO: 393: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 527 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: pept__de (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..527
(D) OTHER INFORMATION: / Ceres Seq. ID 2027301 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 393: Met Ala Leu Pro Ser Cys Leu Lys Thr Gly Ala Leu Met Ser Pro Ala 1 5 10 15
Thr Gly Phe Asn Phe Ser Gly Ser Leu Met Lys Ser Asp Ser Gly Phe
20 25 30
Ala Val Pro Thr Lys Leu Gin Ser Thr Arg Lys Gly Asp Arg Glu Arg 35 40 45 Leu Arg Val Gin Ala He Phe Ser Phe Pro Pro Ala Phe Leu Thr Arg 50 55 60
Asn Gly Arg Ala Glu Lys Gin Lys Gin Leu Lys Gin Glu Leu Leu Glu 65 70 75 80
Ala He Glu Pro Leu Glu Arg Gly Ala Thr Ala Ser Pro Asp Asp Gin 85 ' 90 95
Leu Arg He Asp Gin Leu Ala Arg Lys Val Glu Ala Val Asn Pro Thr
100 105 110
Lys Glu Pro Leu Lys Ser Asp Leu Val Asn Gly Lys Trp Glu Leu He 115 120 125 Tyr Thr Thr Ser Ala Ser He Leu Gin Ala Lys Lys Pro Arg Phe Leu 130 135 140
Arg Ser He Thr Asn Tyr Gin Ser He Asn Val Asp Thr Leu Lys Val 145 150 155 160
Gin Asn Met Glu Thr Trp Pro Phe Tyr Asn Ser Val Thr Gly Asp He 165 170 175
Lys Pro Leu Asn Ser Lys Lys Val Ala Val Lys Leu Gin Val Phe Lys 180 185 190 He Leu Gly Phe He Pro He Lys Ala Pro Asp Ser Ala Arg Gly Glu
195 200 205
Leu Glu He Thr Tyr Val Asp Glu Glu Leu Arg Leu Ser Arg Asp Leu
210 215 220 Ser Phe Met Ser His Val Trp Phe His Asp Leu Ser Thr Leu Phe Leu
225 230 235 240
Leu He Tyr Glu Ser Ser He Thr Leu Gin Val Lys Pro He Arg Ser
245 250 255
Glu Leu Val Met Val Arg Tyr Lys Asp His Asn Arg Arg Arg He Glu 260 265 270
Glu Trp Ser Lys Arg Trp Ser Glu Leu Val Gly Ser Val Glu Thr Gly
275 280 285
Arg Lys Ser Leu Ser Glu Thr Thr Gin Pro Leu Phe Lys Thr Pro Leu
290 295 300 Glu Lys Leu Cys Pro Val Leu He Ser Met Ala Leu Pro Trp Cys Leu
305 310 315 " " 320
Lys Thr Gly Val Leu Thr Ser Pro Ala Ala Gly Phe Asn His Pro Ser
325 330 335
Asp Ser Gly Phe Ala Val Pro Thr Lys Leu Leu Ser He Arg Lys Gly 340 345 350
Asp A.rg Glu Arg Leu A.rg He Gin Ala Val Phe Ser Phe Pro Pro Arg
355 360 365
Asn Gly Gly Ala Glu Lys A.rg Lys Gin Leu Lys His Glu Leu Val Glu
370 375 380 Ala He Glu Pro Leu Glu Arg Gly Ala Thr Ala Ser Pro Asp Asp Gin
385 390 395 400
Leu Leu He A.sp Gin Leu A.la Arg Lys Val Glu Ala Val Asn Pro Thr
405 410 415
Lys Glu Pro Leu Lys Ser Asp Leu He Asn Gly Lys Trp Glu Leu He 420 425 430
Tyr Thr Thr Ser Ala Ala He Leu Gin Ala Lys Lys Pro Arg Phe Leu
435 440 445
Arg Ser Leu Thr Asn Tyr Gin Cys He Asn Met Asp Thr Leu Lys Val
450 455 460 Gin Arg Met Glu Thr Trp Pro Phe Tyr Asn Ser Val Thr Gly Asp Leu
465 470 475 480
Thr Pro Leu Asn Ser Lys Thr Val Ala Val Lys Leu Gin Val Phe Lys
485 490 495
He Leu Gly Phe He Pro Val Lys Ala Pro Asp Gly Thr Ala Arg Gly 500 505 510
Glu Leu Glu He Thr Tyr Val Asp Glu Glu Leu Arg Asp Lys Leu
515 520 525
(2) INFORMATION FOR SEQ ID NO: 394: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 515 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..515
(D) OTHER INFORMATION: / Ceres Seq. ID 2027302 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 394: Met Ser Pro Ala Thr Gly Phe Asn Phe Ser Gly Ser Leu Met Lys Ser 1 5 10 15
Asp Ser Gly Phe Ala Val Pro Thr Lys Leu Gin Ser Thr Arg Lys Gly
20 25 30
Asp Arg Glu Arg Leu Arg Val Gin Ala He Phe Ser Phe Pro Pro Ala 35 40 45
Phe Leu Thr Arg Asn Gly A.rg Ala Glu Lys Gin Lys Gin Leu Lys Gin 50 55 60 Glu Leu Leu Glu Ala He Glu Pro Leu Glu Arg Gly Ala Thr Ala Ser 65 70 75 80
Pro Asp Asp Gin Leu Arg He Asp Gin Leu Ala Arg Lys Val Glu Ala 85 90 95 Val Asn Pro Thr Lys Glu Pro Leu Lys Ser Asp Leu Val Asn Gly Lys 100 105 110
Trp Glu Leu He Tyr Thr Thr Ser Ala Ser He Leu Gin Ala Lys Lys
115 120 125
Pro Arg Phe Leu Arg Ser He Thr Asn Tyr Gin Ser He Asn Val Asp 130 135 140
Thr Leu Lys Val Gin Asn Met Glu Thr Trp Pro Phe Tyr Asn Ser Val
145 150 155 160
Thr Gly Asp He Lys Pro Leu Asn Ser Lys Lys Val Ala Val Lys Leu
165 170 175 Gin Val Phe Lys He Leu Gly Phe He Pro He Lys Ala Pro Asp Ser
180 185 190
Ala Arg Gly Glu Leu Glu He Thr Tyr Val Asp Glu Glu Leu Arg Leu
195 200 205
Ser Arg Asp Leu Ser Phe Met Ser His Val Trp Phe His Asp Leu Ser 210 215 220
Thr Leu Phe Leu Leu He Tyr Glu Ser Ser He Thr Leu Gin Val Lys
225 230 235 240
Pro He Arg Ser Glu Leu Val Met Val A.rg Tyr Lys Asp His Asn Arg
245 250 255 Arg Arg He Glu Glu Trp Ser Lys Arg Trp Ser Glu Leu Val Gly Ser
260 265 270
Val Glu Thr Gly Arg Lys Ser Leu Ser Glu Thr Thr Gin Pro Leu Phe
275 280 285
Lys Thr Pro Leu Glu Lys Leu Cys Pro Val Leu He Ser Met Ala Leu 290 295 300
Pro Trp Cys Leu Lys Thr Gly Val Leu Thr Ser Pro Ala Ala Gly Phe
305 310 315 320
Asn His Pro Ser Asp Ser Gly Phe Ala Val Pro Thr Lys Leu Leu Ser
325 330 335 He Arg Lys Gly Asp Arg Glu Arg Leu Arg He Gin Ala Val Phe Ser
340 345 350
Phe Pro Pro Arg Asn Gly Gly Ala Glu Lys Arg Lys Gin Leu Lys His
355 360 365
Glu Leu Val Glu Ala He Glu Pro Leu Glu Arg Gly Ala Thr Ala Ser 370 375 380
Pro Asp Asp Gin Leu Leu He Asp Glr. Leu Ala Arg Lys Val Glu Ala
385 " 390 395 400
Val Asn Pro Thr Lys Glu Pro Leu Lys Ser Asp Leu He Asn Gly Lys
405 410 415 Trp Glu Leu He Tyr Thr Thr Ser Ala Ala He Leu Gin Ala Lys Lys
420 425 430
Pro Arg Phe Leu Arg Ser Leu Thr Asn Tyr Gin Cys He Asn Met Asp
435 440 445
Thr Leu Lys Val Gin Arg Met Glu Thr Trp Pro Phe Tyr Asn Ser Val 450 455 460
Thr Gly Asp Leu Thr Pro Leu Asn Ser Lys Thr Val Ala Val Lys Leu 465 470 475 480
Gin Val Phe Lys He Leu Gly Phe He Pro Val Lys Ala Pro Asp Gly 485 490 495 Thr Ala Arg Gly Glu Leu Glu He Thr Tyr Val Asp Glu Glu Leu Arg 500 505 510
Asp Lys Leu 515 (2) INFORMATION FOR SEQ ID NO: 395: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 502 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..502
(D) OTHER INFORMATION: / Ceres Seq. ID 2027303 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 395: Met Lys Ser Asp Ser Gly Phe Ala Val Pro Thr Lys Leu Gin Ser Thr 1 5 10 " 15
Arg Lys Gly Asp Arg Glu Arg Leu Arg Val Gin Ala He Phe Ser Phe
20 25 30
Pro Pro Ala Phe Leu Thr Arg Asn Gly Arg Ala Glu Lys Gin Lys Gin 35 40 45 Leu Lys Gin Glu Leu Leu Glu Ala He Glu Pro Leu Glu Arg Gly Ala 50 55 60
Thr Ala Ser Pro Asp Asp Gin Leu Arg He Asp Gin Leu Ala Arg Lys 65 70 75 80
Val Glu Ala Val Asn Pro Thr Lys Glu Pro Leu Lys Ser Asp Leu Val 85 90 95
Asn Gly Lys Trp Glu Leu He Tyr Thr Thr Ser Ala Ser He Leu Gin
100 105 110
Ala Lys Lys Pro Arg Phe Leu Arg Ser He Thr Asn Tyr Gin Ser He 115 120 125 Asn Val Asp Thr Leu Lys Val Gin Asn Met Glu Thr Trp Pro Phe Tyr 130 135 140
Asn Ser Val Thr Gly Asp He Lys Pro Leu Asn Ser Lys Lys Val Ala 145 150 155 160
Val Lys Leu Gin Val Phe Lys He Leu Gly Phe He Pro He Lys Ala 165 170 175
Pro Asp Ser Ala Arg Gly Glu Leu Glu He Thr Tyr Val Asp Glu Glu
180 185 190
Leu Arg Leu Ser Arg Asp Leu Ser Phe Met Ser His Val Trp Phe His 195 200 205 Asp Leu Ser Thr Leu Phe Leu Leu He Tyr Glu Ser Ser He Thr Leu 210 215 220
Gin Val Lys Pro He Arg Ser Glu Leu Val Met Val Arg Tyr Lys Asp 225 230 235 240
His Asn Arg Arg Arg He Glu Glu Trp Ser Lys Arg Trp Ser Glu Leu " 245 250 255
Val Gly Ser Val Glu Thr Gly Arg Lys Ser Leu Ser Glu Thr Thr Gin
260 265 270
Pro Leu Phe Lys Thr Pro Leu Glu Lys Leu Cys Pro Val Leu He Ser 275 280 285 Met Ala Leu Pro Trp Cys Leu Lys Thr Gly Val Leu Thr Ser Pro Ala 290 295 300
Ala Gly Phe Asn His Pro Ser Asp Ser Gly Phe Ala Val Pro Thr Lys 305 310 315 320
Leu Leu Ser He Arg Lys Gly Asp Arg Glu Arg Leu Arg He Gin Ala 325 330 335
Val Phe Ser Phe Pro Pro Arg Asn Gly Gly Ala Glu Lys Arg Lys Gin
340 345 350
Leu Lys His Glu Leu Val Glu Ala He Glu Pro Leu Glu Arg Gly Ala 355 360 365 Thr Ala Ser Pro Asp Asp Gin Leu Leu He Asp Gin Leu Ala Arg Lys 370 375 380
Val Glu Ala Val Asn Pro Thr Lys Glu Pro Leu Lys Ser Asp Leu He 385 390 395 400
Asn Gly Lys Trp Glu Leu He Tyr Thr Thr Ser Ala Ala He Leu Gin 405 410 415
Ala Lys Lys Pro Arg Phe Leu Arg Ser Leu Thr Asn Tyr Gin Cys He 420 425 430 Asn Met Asp Thr Leu Lys Val Gin A.rg Met Glu Thr Trp Pro Phe Tyr
435 440 445
Asn Ser Val Thr Gly Asp Leu Thr Pro Leu Asn Ser Lys Thr Val Ala
450 455 460
Val Lys Leu Gin Val Phe Lys He Leu Gly Phe He Pro Val Lys Ala 465 470 475 480
Pro Asp Gly Thr Ala Arg Gly Glu Leu Glu He Thr Tyr Val Asp Glu
485 490 495
Glu Leu Arg Asp Lys Leu 500
(2) INFORMATION FOR SEQ ID NO: 396:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 539 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: DNA (genomic)
(ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..539 (D) OTHER INFORMATION: / Ceres Seq. ID 2027375 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 396: actgtgttcg ataataatgt cgacaggaga agcgatacca agagtcgccg tcgtcgtttt 60 cattctcaac ggaaactcaa tcttattagg tcgccgccgt tcctcaatcg gcaactccac 120 tttcgctctt cccggtggcc acctcgaatt cggagagagc tttgaagaat gtgcagcgag 180 agaagtaatg gaggaaacag gtctaaagat tgaaaagatg aagcttttga ctgttacaaa 240 caatgtcttc aaagaagcac caacgccatc acactacgtc tctgtttcga tacgtgcggt 300 gttggtggat ccaagtcaag aaccgaagaa tatggaacca gagaagtgtg aaggatggga 360 ttggtatgat tgggagaatc taccaaagcc tttgttttgg ccacttgaga aattgtttgg 420 aagtggtttc aatcctttca ctcatggtgg tggagactaa tagatgtaag agttaatgat 480 tgatttggga ttgaatgttg cacaaattgg gcatttggtc tagtggtatg atctygctt (2) INFORMATION FOR SEQ ID NO: 397: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 152 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..152 (D) OTHER INFORMATION: / Ceres Seq. ID 2027376
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 397: Leu Cys Ser He He Met Ser Thr Gly Glu Ala He Pro Arg Val Ala 1 5 10 15
Val Val Val Phe He Leu Asn Gly Asn Ser He Leu Leu Gly Arg Arg 20 25 30
Arg Ser 3er He Gly Asn Ser Thr Phe Ala Leu Pro Gly Gly His Leu
35 40 45
Glu Phe Gly Glu Ser Phe Glu Glu Cys Ala Ala Arg Glu Val Met Glu
50 55 60
Glu Thr Gly Leu Lys He Glu Lys Met Lys Leu Leu Thr Val Thr Asn
65 70 75 80
Asn Val Phe Lys Glu Ala Pro Thr Pro Ser His Tyr Val Ser Val Ser
85 90 95
He Arg Ala Val Leu Val Asp Pro Ser Gin Glu Pro Lys Asn Met Glu
100 105 110
Pro Glu Lys Cys Glu Gly Trp Asp Trp Tyr Asp Trp Glu Asn Leu Pro
115 120 125
Lys Pro Leu Phe Trp Pro Leu Glu Lys Leu Phe Gly Ser Gly Phe Asn
130 135 140
Pro Phe Thr His Gly Gly Gly Asp 145 150
(2) INFORMATION FOR SEQ ID NO: 398: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 147 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..147
(D) OTHER INFORMATION: / Ceres Seq. ID 2027377 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 398: Met Ser Thr Gly Glu Ala He Pro Arg Val Ala Val Val Val Phe He 1 5 10 15
Leu A.sn Gly Asn Ser He Leu Leu Gly Arg Arg Arg Ser Ser He Gly
20 25 30
Asn Ser Thr Phe Ala Leu Pro Gly Gly His Leu Glu Phe Gly Glu Ser 35 40 45 Phe Glu Glu Cys Ala Ala Arg Glu Val Met Glu Glu Thr Gly Leu Lys 50 55 60
He Glu Lys Met Lys Leu Leu Thr Val Thr Asn Asn Val Phe Lys Glu 65 70 75 80
Ala Pro Thr Pro Ser His Tyr Val Ser Val Ser He Arg Ala Val Leu 85 90 95
Val Asp Pro Ser Gin Glu Pro Lys Asn Met Glu Pro Glu Lys Cys Glu
100 105 110
Gly Trp Asp Trp Tyr Asp Trp Glu Asn Leu Pro Lys Pro Leu Phe Trp 115 120 125 Pro Leu Glu Lys Leu Phe Gly Ser Gly Phe Asn Pro Phe Thr His Gly 130 135 140
Gly Gly Asp 145
(2) INFORMATION FOR SEQ ID NO: 399: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 90 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..90
(D) OTHER INFORMATION: / Ceres Seq. ID 2027378 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 399:
Met Glu Glu Thr Gly Leu Lys He Glu Lys Met Lys Leu Leu Thr Val 1 5 10 15
Thr Asn Asn Val Phe Lys Glu Ala Pro Thr Pro Ser His Tyr Val Ser 20 25 30 Val Ser He Arg Ala Val Leu Val Asp Pro Ser Gin Glu Pro Lys Asn 35 40 45
Met Glu Pro Glu Lys Cys Glu Gly Trp Asp Trp Tyr Asp Trp Glu Asn
50 55 60
Leu Pro Lys Pro Leu Phe Trp Pro Leu Glu Lys Leu Phe Gly Ser Gly 65 70 75 80
Phe Asn Pro Phe Thr His Gly Gly Gly Asp
85 90
(2) INFORMATION FOR SEQ ID NO: 400: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 3983 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..3983
(D) OTHER INFORMATION: / Ceres Seq. ID 2028729 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 400: atgaacacga cgccgtttca ctcggatcct ccgccgtcga ggatccagcg taagctcgtt 60 gtcgaagttg ttgaagctcg taatattctc cctaaagatg gtcaaggaag ctctagcgct 120 tacgtcgttg tcgatttcga tgctcagaag aaacgaacct ccactaagtt ccgtgaccta 180 aaccctattt ggaacgagat gcttgatttc gccgtctccg atcccaaaaa catggattac 240 gacgagctcg atatcgaggt ttataacgat aaaagatttg gtaacggagg tggccggaag 300 aatcattttc tcggtagggt taagatctat ggaagccagt tctcgcgaag aggtgaagaa 360 ggtcttgtgt atttcccttt ggagaagaag agtgtgttca gctggattcg cggcgagatt 420 ggactcaaaa tctactatta cgacgaagcc gccgacgaag acacggcggg tggaggtgga 480 ggacagcaac aacaacagca acagcaacaa tttcatccgc cgcaacaaga agccgatgaa 540 caacaacacc agcaacaatt tcatcctccg ccgcagcaga tgatgaatat accaccggag 600 aaacctaatg tagttgtggt tgaagaaggt agggttttcg aatcggctca gagtcagcgc 660 tatacagaga cacatcagca acctccggtg gttattgttg aagaatcacc accgcagcat 720 gtaatgcaag gtccaaatga taaccatcct caccgaaatg ataaccatcc tcaacggcca 780 ccgtctccgc cgccacctcc atcggctggg gaagtacatt attatccacc ggaagtgagg 840 aagatgcaag taggaagacc tcccggcgga gatagaatta gggttacgaa gagaccaccg 900 aatggagatt attcacctag ggttatcaat agcaaaactg gaggaggaga gacgacgatg 960 gagaagaaga ctcatcatcc ttacaatctt gttgagccaa tgcagtatct cttcgttcgg 1020 attgtgaagg cgcgtggctt accacctaac gagagcgcgt atgttaaggt acggacgtcg 1080 aaccatttcg tcaggtctaa accggccgtt aaccggcccg gcgaatcggt tgattcaccg 1140 gagtggaatc aggtttttgc tcttggtcat aaccggtctg attccgctgt aactggtgcg 1200 actcttgaga tctctgcttg ggatgcttcg tcggagagtt ttctcggagg agtttgtttt 1260 gatctctctg aggttccggt tcgtgacccg ccggatagtc cgcttgctcc tcagtggtat 1320 cggctcgaag gctccggcgc ggatcagaac tctgggagaa tttccggtga cattcagctc 1380 tctgtttgga ttggtactca ggtagatgag gcatttccgg aggcttggag ctctgatgct 1440 ccgcatgtag ctcacacgcg ttctaaggtg tεtcaatcgc cgaaactttg gtacttgaga 1500 gtgacggttc ttgaggcaca ggatttacac atagctccta atctcccgcc gttgactgcg 1560 cctgagattc gtgtgaaagc tcaattaggg tttcagtcgg cgcgtacaag aagaggctca 1620 atgaataacc acagtggttc gtttcattgg catgaggata tgatctttgt tgctggagag 1680 ccgttggaag attgcttggt tctgatggtg gaagaccgga cgactaaaga agcaacactt 1740 ctaggacatg ccatgatccc agtgagctcc atcgagcagc gaattgatga gcgttttgtg 1800 ccgtcgaaat ggcacactct ggaaggagaa ggtggaggtg gaggtggagg aggaggacct 1860 ggaggtggtg gtggtggtgg accttattgt ggaaggatta gccttagact ttgtctcgaa 1920 ggtgggtatc atgtgcttga agaggcggcg catgtatgca gcgatttccg tccgacggct 1980 aagcagctat ggaaaccgcc gattggaata cttgagttgg ggattcttgg agctcgtggg 2040 ttgttgccga tgaaggcgaa aaacggaggg aaaggttcca ctgatgctta ttgtgttgct 2100 aagtacggga agaaatgggt caggactcga accataacag acagttttga cccgaggtgg 2160 cacgagcagt atacgtggca ggtttatgat ccttgcaccg tgctaactgt tggagtcttc 2220 gacaattgga ggatgttctc tgacgcctcc gatgatagac ctgacacacg gattgggaag 2280 atacggatcc gggtgtcgac gttagagagc aacaaagtgt acaccaattc atatcctctg 2340 ttggttttgt tacctagcgg tatgaaaaaa atgggtgaaa ttgaagtggc agtccggttt 2400 gcatgcccgt ctctgctgcc tgatgtttgt gcagcttatg gacagccgct tctgcctcgg 2460 atgcactaca taaggcctct aggtgtagca caacaagatg cattaagagg ggccgccacg 2520 aaaatggtag cagcttggct ggctcgagca gaaccaccat tgggaccaga ggtagttcga 2580 tatatgttag atgcagattc gcatgcatgg agcatgagga aaagcaaagc gaattggtac 2640 agaattgttg gtgttttagc ttgggcagtg ggtttagcta agtggttgga taatatcagg 2700 cggtggagga atccagtgac gacggtgcta gtccatattc tatatctggt tcttgtttgg 2760 taccctgatt tggtagtccc gactgcattc ttgtacgtgg tgatgatcgg agtttggtac 2820 taccggttta gacccaagat accggctggt atggatatcc gcttatcaca agctgaaacc 2880 gtcgatcctg atgagctaga tgaagaattc gacaccatac caagctcaag gcgaccagaa 2940 gtaatccgag ctaggtacga ccgattaagg atcttagcag tgagggttca gaccattcta 3000 ggagattttg cagcgcaagg agaacggatt caagcgttgg ttagctggag agatccgaga 3060 gcgacaaagc tgttcatagc aatctgtttg gtaatcacaa tagttctgta tgcagttcct 3120 gcgaaaatgg tggcggtggc tctaggagtt tcagatagtg tgccaacggc gaaacaagac 3180 acgaaagaat ctctaaagaa atcattttca tcgcttcgct tcgatttttc ttcaatggct 3240 gtcgtcggcg ctccaatatc gtctccggcg gctcagctgc agacacaatt tctctccaat 3300 cccattctcc cccgctttcg ccggtctttc tccaccggaa aatcaccagc aactttctcc 3360 gtcgtagcta tggctcccca gaaaaaggtg aacaaatatg atgccaagtg gaagaaacaa 3420 tggtacggag ctggattgtt tttcgaaggg agtgagcaaa taaacgttga tgttttcaag 3480 aagctggaga agcgaaaagt gttgagcaac gttgagaaat ctggcctgct gtcaaaagca 3540 gaggggttgg gactcacatt gtcatctctt gagaagctta aagtcttctc caaagcagag 3600 gaccttggtc ttctcagtct ccttgagaac ttagctggaa catcgcctgc ggtcttagcc 3660 tcggctgcat taccagctct cacggctgct attgtagccg tggtgttgat cccggatgac 3720 tcaactactc tagtggttgc tcaggcggtt ttggccggtg ctcttgcgct tacaggggtt 3780 gttttgttgg ttggttctgt tgttttggat ggacttcaag aagctgactg attctttctc 3840 tgtaaaccga acataaaccc atgtcttgtc caattgattt ttgtcagttg ctgatttata 3900 gctgtatggt tcagttgttt atggttagtc caagacataa gctgagtgat agaaagaagc 3960 tttataataa ttaaacaaat att (2) INFORMATION FOR SEQ ID NO: 40.
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1276 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..1276 (D) OTHER INFORMATION: / Ceres Seq. ID 2028730
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 401: Met Asn Thr Thr Pro Phe His Ser Asp Pro Pro Pro Ser Arg He Gin 1 5 10 15
Arg Lys Leu Val Val Glu Val Val Glu Ala Arg Asn He Leu Pro Lys
20 25 30
Asp Gly Gin Gly Ser Ser Ser Ala Tyr Val Val Val Asp Phe Asp Ala
35 40 45
Gin Lys Lys Arg Thr Ser Thr Lys Phe Arg Asp Leu Asn Pro He Trp
50 55 60
Asn Glu Met Leu Asp Phe Ala Val Ser Asp Pro Lys Asn Met Asp Tyr 65 70 75 80
Asp Glu Leu Asp He Glu Val Tyr Asn Asp Lys Arg Phe Gly Asn Gly
85 90 95
Gly Gly Arg Lys Asn His Phe Leu Gly Arg Val Lys He Tyr Gly Ser
100 105 110
Gin Phe Ser Arg Arg Gly Glu Glu Gly Leu Val Tyr Phe Pro Leu Glu
115 120 125
Lys Lys Ser Val Phe Ser Trp He Arg Gly Glu He Gly Leu Lys He
130 135 140
Tyr Tyr Tyr Asp Glu Ala Ala Asp Glu Asp Thr Ala Gly Gly Gly Gly 145 150 155 160
Gly Gin Gin Gin Gin Gin Gin Gin Gin Gin Phe His Pro Pro Gin Gin
165 170 175
Glu Ala Asp Glu Gin Gin His Gin Gin Gin Phe His Pro Pro Pro Gin
180 185 190
Gin Met Met Asn He Pro Pro Glu Lys Pro Asn Val Val Val Val Glu
195 200 205
Glu Gly Arg Val Phe Glu Ser Ala Gin Ser Gin Arg Tyr Thr Glu Thr
210 215 220
His Gin Gin Pro Pro Val Val He Val Glu Glu Ser Pro Pro Gin His 225 230 235 240
Val Met Gin Gly Pro Asn Asp Asn His Pro His Arg Asn Asp Asn His
245 250 255
Pro Gin Arg Pro Pro Ser Pro Pro Pro Pro Pro Ser Ala Gly Glu Val
260 265 270
His Tyr Tyr Pro Pro Glu Val Arg Lys Met Gin Val Gly Arg Pro Pro
275 280 285
Gly Gly Asp Arg He Arg Val Thr Lys Arg Pro Pro Asn Gly Asp Tyr 290 295 300 Ser Pro Arg Val He Asn Ser Lys Thr Gly Gly Gly Glu Thr Thr Met
305 310 315 320
Glu Lys Lys Thr His His Pro Tyr Asn Leu Val Glu Pro Met Gin Tyr 325 330 335
Leu Phe Val Arg He Val Lys Ala Arg Gly Leu Pro Pro Asn Glu Ser 340 345 350
Ala Tyr Val Lys Val Arg Thr Ser Asn His Phe Val Arg Ser Lys Pro 355 360 365
Ala Val Asn Arg Pro Gly Glu Ser Val Asp Ser Pro Glu Trp Asn Gin 370 375 380
Val Phe Ala Leu Gly His Asn Arg Ser Asp Ser Ala Val Thr Gly Ala
385 390 395 400
Thr Leu Glu He Ser Ala Trp Asp Ala Ser Ser Glu Ser Phe Leu Gly 405 410 415
Gly Val Cys Phe Asp Leu Ser Glu Val Pro Val Arg Asp Pro Pro Asp 420 425 430
Ser Pro Leu Ala Pro Gin Trp Tyr A.rg Leu Glu Gly Ser Gly Ala Asp 435 440 445
Gin Asn Ser Gly Arg He Ser Gly Asp He Gin Leu Ser Val Trp He 450 455 460
Gly Thr Gin Val Asp Glu Ala Phe Pro Glu Ala Trp Ser Ser Asp Ala
465 470 475 480
Pro His Val Ala His Thr Arg Ser Lys Val Tyr Gin Ser Pro Lys Leu 485 490 495
Trp Tyr Leu Arg Val Thr Val Leu Glu Ala Gin Asp Leu His He Ala 500 505 510
Pro Asn Leu Pro Pro Leu Thr Ala Pro Glu He Arg Val Lys Ala Gin 515 520 525
Leu Gly Phe Gin Ser Ala Arg Thr Arg Arg Gly Ser Met Asn Asn His 530 535 540
Ser Gly Ser Phe His Trp His Glu Asp Met He Phe Val Ala Gly Glu
545 550 555 560
Pro Leu Glu Asp Cys Leu Val Leu Met Val Glu Asp Arg Thr Thr Lys 565 570 575
Glu Ala Thr Leu Leu Gly His Ala Met He Pro Val Ser Ser He Glu 580 585 590
Gin Arg He Asp Glu Arg Phe Val Pro Ser Lys Trp His Thr Leu Glu 595 600 605
Gly Glu Gly Gly Gly Gly Gly Gly Gly Gly Gly Pro Gly Gly Gly Gly 610 615 620
Gly Gly Gly Pro Tyr Cys Gly Arg He Ser Leu Arg Leu Cys Leu Glu
625 630 635 640
Gly Gly Tyr His Val Leu Glu Glu Ala Ala His Val Cys Ser Asp Phe 645 650 655
Arg Pro Thr Ala Lys Gin Leu Trp Lys Pro Pro He Gly He Leu Glu 660 665 670
Leu Gly He Leu Gly Ala Arg Gly Leu Leu Pro Met Lys Ala Lys Asn 675 680 685
Gly Gly Lys Gly Ser Thr Asp Ala Tyr Cys Val Ala Lys Tyr Gly Lys 690 695 700
Lys Trp Val Arg Thr Arg Thr He Thr Asp Ser Phe Asp Pro Arg Trp
705 710 715 720
His Glu Gin Tyr Thr Trp Gin Val Tyr Asp Pro Cys Thr Val Leu Thr 725 730 735
Val Gly Val Phe Asp Asn Trp Arg Met Phe Ser Asp Ala Ser Asp Asp 740 745 750
Arg Pro Asp Thr Arg He Gly Lys He Arg He Arg Val Ser Thr Leu 755 760 765
Glu Ser Asn Lys Val Tyr Thr Asn Ser Tyr Pro Leu Leu Val Leu Leu 770 775 780
Pro Ser Gly Met Lys Lys Met Gly Glu He Glu Val Ala Val Arg Phe
785 790 795 800 Ala Cys Pro Ser Leu Leu Pro Asp Val Cys Ala Ala Tyr Gly Gin Pro
805 810 815
Leu Leu Pro Arg Met His Tyr He Arg Pro Leu Gly Val Ala Gin Gin 820 825 830 Asp Ala Leu Arg Gly Ala Ala Thr Lys Met Val Ala Ala Trp Leu Ala 835 840 845
Arg Ala Glu Pro Pro Leu Gly Pro Glu Val Val Arg Tyr Met Leu Asp
850 855 860
Ala Asp Ser His Ala Trp Ser Met Arg Lys Ser Lys Ala Asn Trp Tyr 865 " 870 875 880
Arg He Val Gly Val Leu Ala Trp Ala Val Gly Leu Ala Lys Trp Leu
885 890 895
Asp Asn He Arg Arg Trp Arg Asn Pro Val Thr Thr Val Leu Val His 900 905 910 He Leu Tyr Leu Val Leu Val Trp Tyr Pro Asp Leu Val Val Pro Thr 915 920 925
Ala Phe Leu Tyr Val Val Met He Gly Val Trp Tyr Tyr Arg Phe Arg
930 935 940
Pro Lys He Pro Ala Gly Met Asp He Arg Leu Ser Gin Ala Glu Thr 945 950 955 960
Val Asp Pro Asp Glu Leu Asp Glu Glu Phe Asp Thr He Pro Ser Ser
965 970 975
Arg A.rg Pro Glu Val He Arg Ala Arg Tyr A.sp Arg Leu A.rg He Leu 980 985 990 Ala Val Arg Val Gin Thr He Leu Gly Asp Phe Ala Ala Gin Gly Glu 995 1000 1005
Arg He Gin Ala Leu Val Ser Trp Arg Asp Pro Arg Ala Thr Lys Leu
1010 1015 1020
Phe He Ala He Cys Leu Val He Thr He Val Leu Tyr Ala Val Pro 1025 1030 1035 1040
Ala Lys Met Val Ala Val A.la Leu Gly Val Ser Asp Ser Val Pro Thr
1045 1050 1055
Ala Lys Gin Asp Thr Lys Glu Ser Leu Lys Lys Ser Phe Ser Ser Leu 1060 1065 1070 Arg Phe Asp Phe Ser Ser Met Ala Val Val Gly Ala Pro He Ser Ser 1075 1080 1085
Pro Ala Ala Gin Leu Gin Thr Gin Phe Leu Ser Asn Pro He Leu Pro
1090 1095 1100
Arg Phe Arg Arg Ser Phe Ser Thr Gly Lys Ser Pro Ala Thr Phe Ser 1105 1110 1115 1120
Val Val Ala Met Ala Pro Gin Lys Lys Val Asn Lys Tyr Asp Ala Lys
1125 1130 1135
Trp Lys Lys Gin Trp Tyr Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu 1140 1145 1150 Gin He Asn Val Asp Val Phe Lys Lys Leu Glu Lys Arg Lys Val Leu 1155 1160 1165
Ser Asn Val Glu Lys Ser Gly Leu Leu Ser Lys Ala Glu Gly Leu Gly
1170 1175 1180
Leu Thr Leu Ser Ser Leu Glu Lys Leu Lys Val Phe Ser Lys Ala Glu 1185 1190 1195 ' 1200
Asp Leu Gly Leu Leu Ser Leu Leu Glu Asn Leu Ala Gly Thr Ser Pro
1205 1210 1215
Ala Val Leu Ala Ser Ala Ala Leu Pro Ala Leu Thr Ala Ala He Val 1220 1225 1230 Ala Val Val Leu He Pro Asp Asp Ser Thr Thr Leu Val Val Ala Gin 1235 1240 1245
Ala Val Leu Ala Gly Ala Leu Ala Leu Thr Gly Val Val Leu Leu Val
1250 1255 1260
Gly Ser Val Val Leu Asp Gly Leu Gin Glu Ala Asp 1265 1270 1275
(2) INFORMATION FOR SEQ ID NO: 402: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1210 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..1210
(D) OTHER INFORMATION: / Ceres Seq. ID 2028731 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 402:
Met Leu Asp Phe Ala Val Ser Asp Pro Lys Asn Met Asp Tyr Asp Glu 1 5 10 15
Leu Asp He Glu Val Tyr Asn Asp Lys Arg Phe Gly Asn Gly Gly Gly 20 25 30 Arg Lys Asn His Phe Leu Gly Arg Val Lys He Tyr Gly Ser Gin Phe 35 40 45
Ser Arg Arg Gly Glu Glu Gly Leu Val Tyr Phe Pro Leu Glu Lys Lys
50 55 60
Ser Val Phe Ser Trp He Arg Gly Glu He Gly Leu Lys He Tyr Tyr 65 70 75 80
Tyr Asp Glu Ala Ala Asp Glu Asp Thr Ala Gly Gly Gly Gly Gly Gin
85 90 95
Gin Gin Gin Gin Gin Gin Gin Gin Phe His Pro Pro Gin Gin Glu Ala 100 105 110 Asp Glu Gin Gin His Gin Gin Gin Phe His Pro Pro Pro Gin Gin Met 115 120 125
Met Asn He Pro Pro Glu Lys Pro Asn Val Val Val Val Glu Glu Gly
130 135 140
Arg Val Phe Glu Ser Ala Gin Ser Gin Arg Tyr Thr Glu Thr His Gin 145 150 155 160
Gin Pro Pro Val Val He Val Glu Glu Ser Pro Pro Gin His Val Met
165 170 175
Gin Gly Pro Asn Asp Asn His Pro His Arg Asn Asp Asn His Pro Gin 180 185 190 Arg Pro Pro Ser Pro Pro Pro Pro Pro Ser Ala Gly Glu Val His Tyr 195 200 205
Tyr Pro Pro Glu Val Arg Lys Met Gin Val Gly Arg Pro Pro Gly Gly
210 215 220
Asp Arg He Arg Val Thr Lys Arg Pro Pro Asn Gly Asp Tyr Ser Pro 225 230 235 240
Arg Val He Asn Ser Lys Thr Gly Gly Gly Glu Thr Thr Met Glu Lys
245 250 255
Lys Thr His His Pro Tyr Asn Leu Val Glu Pro Met Gin Tyr Leu Phe 260 265 270 Val Arg He Val Lys Ala Arg Gly Leu Pro Pro Asn Glu Ser Ala Tyr 275 280 285
Val Lys Val Arg Thr Ser Asn His Phe Val Arg Ser Lys Pro Ala Val
290 295 300
Asn Arg Pro Gly Glu Ser Val Asp Ser Pro Glu Trp Asn Gin Val Phe 305 310 315 320
Ala Leu Gly His Asn Arg Ser Asp Ser Ala Val Thr Gly Ala Thr Leu
325 330 335
Glu He Ser Ala Trp Asp Ala Ser Ser Glu Ser Phe Leu Gly Gly Val 340 345 350 Cys Phe Asp Leu Ser Glu Val Pro Val Arg Asp Pro Pro Asp Ser Pro 355 360 365
Leu Ala Pro Gin Trp Tyr Arg Leu Glu Gly Ser Gly Ala Asp Gin Asn
370 375 380
Ser Gly Arg He Ser Gly Asp He Gin Leu Ser Val Trp He Gly Thr 385 390 395 400
Gin Val Asp Glu Ala Phe Pro Glu Ala Trp Ser Ser Asp Ala Pro His 405 410 415 Val Ala His Thr Arg Ser Lys Val Tyr Gin Ser Pro Lys Leu Trp Tyr 420 425 430
Leu Arg Val Thr Val Leu Glu Ala Gin Asp Leu His He Ala Pro Asn 435 440 445
Leu Pro Pro Leu Thr Ala Pro Glu He Arg Val Lys Ala Gin Leu Gly 450 455 460
Phe Gin Ser Ala Arg Thr Arg Arg Gly Ser Met Asn Asn His Ser Gly
465 470 475 480
Ser Phe His Trp His Glu Asp Met He Phe Val Ala Gly Glu Pro Leu 485 490 495
Glu Asp Cys Leu Val Leu Met Val Glu Asp Arg Thr Thr Lys Glu Ala 500 505 510
Thr Leu Leu Gly His Ala Met He Pro Val Ser Ser He Glu Gin Arg
515 520 525
He Asp Glu Arg Phe Val Pro Ser Lys Trp His Thr Leu Glu Gly Glu 530 535 540
Gly Gly Gly Gly Gly Gly Gly Gly Gly Pro Gly Gly Gly Gly Gly Gly
545 550 555 560
Gly Pro Tyr Cys Gly Arg He Ser Leu Arg Leu Cys Leu Glu Gly Gly 565 570 575
Tyr His Val Leu Glu Glu Ala Ala His Val Cys Ser Asp Phe Arg Pro 580 585 590
Thr Ala Lys Gin Leu Trp Lys Pro Pro He Gly He Leu Glu Leu Gly 595 600 605
He Leu Gly Ala Arg Gly Leu Leu Pro Met Lys Ala Lys Asn Gly Gly 610 615 620
Lys Gly Ser Thr Asp Ala. Tyr Cys Val Ala Lys Tyr Gly Lys Lys Trp
625 630 635 640
Val Arg Thr Arg Thr He Thr Asp Ser Phe Asp Pro Arg Trp His Glu 645 650 655
Gin Tyr Thr Trp Gin Val Tyr Asp Pro Cys Thr Val Leu Thr Val Gly 660 665 670
Val Phe Asp Asn Trp Arg Met Phe Ser Asp Ala Ser Asp Asp Arg Pro 675 680 685
Asp Thr Arg He Gly Lys He Arg He Arg Val Ser Thr Leu Glu Ser 690 695 700
Asn Lys Val Tyr Thr Asn Ser Tyr Pro Leu Leu Val Leu Leu Pro Ser
705 710 715 720
Gly Met Lys Lys Met Gly Glu He Glu Val Ala Val Arg Phe Ala Cys 725 730 735
Pro Ser Leu Leu Pro Asp Val Cys Ala Ala Tyr Gly Gin Pro Leu Leu 740 745 750
Pro Arg Met His Tyr He Arg Pro Leu Gly Val Ala Gin Gin Asp Ala 755 760 765
Leu Arg Gly Ala Ala Thr Lys Met Val Ala Ala Trp Leu Ala Arg Ala 770 775 780
Glu Pro Pro Leu Gly Pro Glu Val Val Arg Tyr Met Leu Asp Ala Asp
785 790 795 800
Ser His Ala Trp Ser Met Arg Lys Ser Lys Ala Asn Trp Tyr Arg He 805 810 815
Val Gly Val Leu Ala Trp Ala Val Gly Leu Ala Lys Trp Leu Asp Asn 820 825 830
He Arg Arg Trp Arg Asn Pro Val Thr Thr Val Leu Val His He Leu 835 840 845
Tyr Leu Val Leu Val Trp Tyr Pro Asp Leu Val Val Pro Thr Ala Phe 850 855 860
Leu Tyr Val Val Met He Gly Val Trp Tyr Tyr Arg Phe Arg Pro Lys
865 870 875 880
He Pro Ala Gly Met Asp He Arg Leu Ser Gin Ala Glu Thr Val Asp 885 890 895
Pro Asp Glu Leu Asp Glu Glu Phe Asp Thr He Pro Ser Ser Arg Arg 900 905 910 Pro Glu Val He Arg Ala Arg Tyr Asp Arg Leu Arg He Leu Ala Val
915 920 925
Arg Val Gin Thr He Leu Gly Asp Phe Ala Ala Gin Gly Glu Arg He
930 935 940 Gin Ala Leu Val Ser Trp Arg Asp Pro Arg Ala Thr Lys Leu Phe He
945 950 955 960
Ala He Cys Leu Val He Thr He Val Leu Tyr Ala Val Pro Ala Lys
965 970 975
Met Val Ala Val Ala Leu Gly Val Ser Asp Ser Val Pro Thr Ala Lys 980 985 990
Gin Asp Thr Lys Glu Ser Leu Lys Lys Ser Phe Ser Ser Leu A.rg Phe
995 1000 1005
Asp Phe Ser Ser Met Ala Val Val Gly Ala Pro He Ser Ser Pro Ala 1010 1015 1020 Ala Gin Leu Gin Thr Gin Phe Leu Ser Asn Pro He Leu Pro Arg Phe 1025 1030 1035 1040
Arg Arg Ser Phe Ser Thr Gly Lys Ser Pro Ala Thr Phe Ser Val Val
1045 1050 1055
Ala Met Ala Pro Gin Lys Lys Val Asn Lys Tyr Asp Ala Lys Trp Lys 1060 1065 1070
Lys Gin Trp Tyr Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu Gin He
1075 1080 1085
Asn Val Asp Val Phe Lys Lys Leu Glu Lys Arg Lys Val Leu Ser Asn 1090 1095 1100 Val Glu Lys Ser Gly Leu Leu Ser Lys Ala Glu Gly Leu Gly Leu Thr 1105 1110 1115 1120
Leu Ser Ser Leu Glu Lys Leu Lys Val Phe Ser Lys Ala Glu Asp Leu
1125 1130 1135
Gly Leu Leu Ser Leu Leu Glu Asn Leu Ala Gly Thr Ser Pro Ala Val 1140 1145 1150
Leu Ala Ser Ala Ala Leu Pro Ala Leu Thr Ala Ala He Val Ala Val
1155 1160 1165
Val Leu He Pro Asp Asp Ser Thr Thr Leu Val Val Ala Gin Ala Val 1170 1175 1180 Leu Ala Gly Ala Leu Ala Leu Thr Gly Val Val Leu Leu Val Gly Ser 1185 1190 1195 1200
Val Val Leu Asp Gly Leu Gin Glu Ala Asp
1205 1210
(2) INFORMATION FOR SEQ ID NO: 403: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1199 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..1199
(D) OTHER INFORMATION: / Ceres Seq. ID 2028732 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 403:
Met Asp Tyr Asp Glu Leu Asp He Glu Val Tyr Asn Asp Lys Arg Phe 1 5 10 15
Gly Asn Gly Gly Gly Arg Lys Asn His Phe Leu Gly Arg Val Lys He 20 25 30 Tyr Gly Ser Gin Phe Ser Arg Arg Gly Glu Glu Gly Leu Val Tyr Phe 35 40 45
Pro Leu Glu Lys Lys Ser Val Phe Ser Trp He Arg Gly Glu He Gly
50 55 60
Leu Lys He Tyr Tyr Tyr Asp Glu Ala Ala Asp Glu Asp Thr Ala Gly 65 70 75 80
Gly Gly Gly Gly Gin Gin Gin Gin Gin Gin Gin Gin Gin Phe His Pro 85 90 95 Pro Gin Gin Glu Ala Asp Glu Gin Gin His Gin Gin Gin Phe His Pro 100 105 110
Pro Pro Gin Gin Met Met Asn He Pro Pro Glu Lys Pro Asn Val Val 115 120 125
Val Val Glu Glu Gly Arg Val Phe Glu Ser Ala Gin Ser Gin Arg Tyr 130 135 140
Thr Glu Thr His Gin Gin Pro Pro Val Val He Val Glu Glu Ser Pro
145 150 155 160
Pro Gin His Val Met Gin Gly Pro Asn Asp Asn His Pro His Arg Asn 165 170 175
Asp Asn His Pro Gin Arg Pro Pro Ser Pro Pro Pro Pro Pro Ser Ala 180 185 190
Gly Glu Val His Tyr Tyr Pro Pro Glu Val Arg Lys Met Gin Val Gly 195 200 205
Arg Pro Pro Gly Gly Asp Arg He Arg Val Thr Lys Arg Pro Pro Asn 210 215 220
Gly Asp Tyr Ser Pro Arg Val He Asn Ser Lys Thr Gly Gly Gly Glu 225 230 235 240
Thr Thr Met Glu Lys Lys Thr His His Pro Tyr Asn Leu Val Glu Pro 245 250 255
Met Gin Tyr Leu Phe Val Arg He Val Lys Ala Arg Gly Leu Pro Pro 260 265 270
Asn Glu Ser Ala Tyr Val Lys Val Arg Thr Ser Asn His Phe Val Arg 275 280 285
Ser Lys Pro Ala Val Asn Arg Pro Gly Glu Ser Val Asp Ser Pro Glu 290 295 300
Trp Asn Gin Val Phe Ala Leu Gly His Asn Arg Ser Asp Ser Ala Val 305 310 315 320
Thr Gly Ala Thr Leu Glu He Ser Ala Trp Asp Ala Ser Ser Glu Ser 325 330 335
Phe Leu Gly Gly Val Cys Phe Asp Leu Ser Glu Val Pro Val Arg Asp 340 345 350
Pro Pro Asp Ser Pro Leu Ala Fro Gin Trp Tyr Arg Leu Glu Gly Ser 355 360 365
Gly Ala Asp Gin Asn Ser Gly Arg He Ser Gly Asp He Gin Leu Ser 370 375 380
Val Trp He Gly Thr Gin Val Asp Glu Ala Phe Pro Glu Ala Trp Ser 385 390 395 400
Ser Asp Ala Pro His Val Ala His Thr Arg Ser Lys Val Tyr Gin Ser 405 410 415
Pro Lys Leu Trp Tyr Leu Arg Val Thr Val Leu Glu Ala Gin Asp Leu 420 425 430
His He Ala Pro Asn Leu Pro Pro Leu Thr Ala Pro Glu He Arg Val 435 440 445
Lys Ala Gin Leu Gly Phe Gin Ser Ala Arg Thr Arg Arg Gly Ser Met 450 455 460
Asn Asn His Ser Gly Ser Phe His Trp His Glu Asp Met He Phe Val 465 470 475 480
Ala Gly Glu Pro Leu Glu Asp Cys Leu Val Leu Met Val Glu Asp Arg 485 490 495
Thr Thr Lys Glu Ala Thr Leu Leu Gly His Ala Met He Pro Val Ser 500 505 510
Ser He Glu Gin Arg He Asp Glu Arg Phe Val Pro Ser Lys Trp His
515 520 525
Thr Leu Glu Gly Glu Gly Gly Gly Gly Gly Gly Gly Gly Gly Pro Gly 530 535 540
Gly Gly Gly Gly Gly Gly Pro Tyr Cys Gly Arg He Ser Leu Arg Leu 545 550 555 560
Cys Leu Glu Gly Gly Tyr His Val Leu Glu Glu Ala Ala His Val Cys 565 570 575
Ser Asp Phe Arg Pro Thr Ala Lys Gin Leu Trp Lys Pro Pro He Gly 580 585 590 He Leu Glu Leu Gly He Leu Gly Ala Arg Gly Leu Leu Pro Met Lys
595 600 605
Ala Lys Asn Gly Gly Lys Gly Ser Thr Asp Ala Tyr Cys Val Ala Lys
610 615 620 Tyr Gly Lys Lys Trp Val Arg Thr Arg Thr He Thr Asp Ser Phe Asp
625 630 635 640
Pro Arg Trp His Glu Gin Tyr Thr Trp Gin Val Tyr Asp Pro Cys Thr
645 650 655
Val Leu Thr Val Gly Val Phe Asp Asn Trp Arg Met Phe Ser Asp Ala 660 665 670
Ser Asp Asp Arg Pro Asp Thr Arg He Gly Lys He Arg He Arg Val
675 680 685
Ser Thr Leu Glu Ser Asn Lys Val Tyr Thr Asn Ser Tyr Pro Leu Leu
690 695 700 Val Leu Leu Pro Ser Gly Met Lys Lys Met Gly Glu He Glu Val Ala
705 710 715 720
Val Arg Phe Ala Cys Pro Ser Leu Leu Pro Asp Val Cys Ala Ala Tyr
725 730 735
Gly Gin Pro Leu Leu Pro Arg Met His Tyr He Arg Pro Leu Gly Val 740 745 750
Ala Gin Gin Asp Ala Leu Arg Gly Ala Ala Thr Lys Met Val Ala Ala
755 760 765
Trp Leu Ala Arg Ala Glu Pro Pro Leu Gly Pro Glu Val Val Arg Tyr
770 775 780 Met Leu Asp Ala Asp Ser His Ala Trp Ser Met Arg Lys Ser Lys Ala
785 790 795 800
Asn Trp Tyr Arg He Val Gly Val Leu Ala Trp Ala Val Gly Leu Ala
805 810 815
Lys Trp Leu Asp Asn He Arg Arg Trp Arg Asn Pro Val Thr Thr Val 820 825 830
Leu Val His He Leu Tyr Leu Val Leu Val Trp Tyr Pro Asp Leu Val
835 840 845
Val Pro Thr Ala Phe Leu Tyr Val Val Met He Gly Val Trp Tyr Tyr
850 855 860 Arg Phe Arg Pro Lys He Pro Ala Gly Met Asp He Arg Leu Ser Gin
865 870 875 880
Ala Glu Thr Val Asp Pro Asp Glu Leu Asp Glu Glu Phe Asp Thr He
885 890 895
Pro Ser Ser Arg Arg Pro Glu Val He Arg Ala Arg Tyr Asp Arg Leu 900 905 910
Arg He Leu Ala Val Arg Val Gin Thr He Leu Gly Asp Phe Ala Ala
915 920 925
Gin Gly Glu Arg He Gin Ala Leu Val Ser Trp Arg Asp Pro Arg Ala
930 935 940 Thr Lys Leu Phe He Ala He Cys Leu Val He Thr He Val Leu Tyr
945 950 955 960
Ala Val Pro Ala Lys Met Val Ala Val Ala Leu Gly Val Ser Asp Ser
965 970 975
Val Pro Thr Ala Lys Gin Asp Thr Lys Glu Ser Leu Lys Lys Ser Phe 980 985 990
Ser Ser Leu Arg Phe Asp Phe Ser Ser Met Ala Val Val Gly Ala Pro
995 1000 1005
He Ser Ser Pro Ala Ala Gin Leu Gin Thr Gin Phe Leu Ser Asn Pro 1010 1015 1020 He Leu Pro Arg Phe Arg Arg Ser Phe Ser Thr Gly Lys Ser Pro Ala 1025 1030 1035 1040
Thr Phe Ser Val Val Ala Met Ala Pro Gin Lys Lys Val Asn Lys Tyr
1045 1050 1055
Asp Ala Lys Trp Lys Lys Gin Trp Tyr Gly Ala Gly Leu Phe Phe Glu 1060 1065 1070
Gly Ser Glu Gin He Asn Val Asp Val Phe Lys Lys Leu Glu Lys Arg 1075 1080 1085 Lys Val Leu Ser Asn Val Glu Lys Ser Gly Leu Leu Ser Lys Ala Glu
1090 1095 1100
Gly Leu Gly Leu Thr Leu Ser Ser Leu Glu Lys Leu Lys Val Phe Ser 1105 1110 1115 1120
Lys Ala Glu Asp Leu Gly Leu Leu Ser Leu Leu Glu Asn Leu Ala Gly
1125 1130 1135
Thr Ser Pro Ala Val Leu Ala Ser Ala Ala Leu Pro Ala Leu Thr Ala
1140 1145 1150
Ala He Val Ala Val Val Leu He Pro Asp Asp Ser Thr Thr Leu Val
1155 1160 1165
Val Ala Gin Ala Val Leu Ala Gly Ala Leu Ala Leu Thr Gly Val Val
1170 1175 1180
Leu Leu Val Gly Ser Val Val Leu Asp Gly Leu Gin Glu Ala Asp 1185 1190 1195
(2) INFORMATION FOR SEQ ID NO: 404: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 528 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..528
(D) OTHER INFORMATION: / Ceres Seq. ID 2029079 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 404: aaaaaactca ctttcacttg cacaaagata aggaaaccat gtctgtgtca gcgatctttg 60 gtaccggaat cgtcaccgtc gctgcttctc cggttctccg ccaatttcaa gttccaaaat 120 tgggtaatgg aggtggatta gggatggtga ttgagtgttc gtcgaggcca cagaagaaat 180 cgacagctca tcacaggaag acgaggccga agaagactca gccttgggac attaagagaa 240 agcctactgt gtatgctcct cttcctcctc ttccggcgga atggagtccg tttactcttg 300 cttccaacga cggtggtgcc gccgttgctg cttctcctgc cggagatttg gtttcaggct 360 ctgcctagtt atatgagcta tctggtggtt tggttgtaat ctagtttgag agcttttgtt 420 ggtgtttgtt tctgttaatg tttttcagtt ttctgctgtc tgtttcttat tatccggttt 480 atgtttggct ggtgaatgaa tgtcaatgga ccaaactgca attttttt (2) INFORMATION FOR SEQ ID NO: 405:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 121 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..121
(D) OTHER INFORMATION: / Ceres Seq. ID 2029080
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 405:
Lys Thr His Phe His Leu His Lys Asp Lys Glu Thr Met Ser Val Ser
1 5 10 15
Ala He Phe Gly Thr Gly He Val Thr Val Ala Ala Ser Pro Val Leu 20 25 30
Arg Gin Phe Gin Val Pro Lys Leu Gly Asn Gly Gly Gly Leu Gly Met 35 40 45
Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser Thr Ala His His 50 55 60
Arg Lys Thr Arg Pro Lys Lys Thr Gin Pro Trp Asp He Lys Arg Lys 65 70 75 80
Pro Thr Val Tyr Ala Pro Leu Pro Pro Leu Pro Ala Glu Trp Ser Pro 85 90 95
Phe Thr Leu Ala Ser Asn Asp Gly Gly Ala Ala Val Ala Ala Ser Pro 100 105 110
Ala Gly Asp Leu Val Ser Gly Ser Ala 115 120
(2) INFORMATION FOR SEQ ID NO: 406: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 109 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: ,A) NAME/KEY: peptide
,B) LOCATION: 1..109
•(D) OTHER INFORMATION: / Ceres Seq. ID 2029081 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:406^: Met Ser Val Ser Ala He Phe Gly Thr Gly He Val Thr Val Ala Ala 1 5 10 15
Ser Pro Val Leu Arg Gin Phe Gin Val Pro Lys Leu Gly Asn Gly Gly
20 25 30
Gly Leu Gly Met Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser 35 40 45 Thr Ala His His Arg Lys Thr Arg Pro Lys Lys Thr Gin Pre Trp Asp 50 55 60
He Lys Arg Lys Pro Thr Val Tyr Ala Pro Leu Pro Frc Leu Pr Ala 65 70 75 80
Glu Trp Ser Pro Phe Thr Leu Ala Ser Asn Asp Gly Gly Ala Ala Val 85 90 95
Ala Ala Ser Pro Ala Gly Asp Leu Val Ser Gly Ser Ala
100 * 105
(2) INFORMATION FOR SEQ ID NO: 407: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 74 amino acids
(B) TYPE: amino acid ;C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74 i'D) OTHER INFORMATION: / Ceres Seq. ID 2029C82 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 407: Met Val He Glu Cys Ser Ser Arg Pro Gin Lys Lys Ser Thr Ala His 1 5 10 15
His Arg Lys Thr Arg Pro Lys Lys Thr Gin Pro Trp Asp He Lys Arg
20 25 30
Lys Pro Thr Val Tyr Ala Pro Leu Pro Pro Leu Pro Ala Glu Trp Ser 35 40 45
Pro Phe Thr Leu Ala Ser Asn Asp Gly Gly Ala Ala Val Ala Ala Ser
50 55 60
Pro Ala Gly Asp Leu Val Ser Gly Ser Ala 65 " 70 (2) INFORMATION FOR SEQ ID NO: 408: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 787 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..787 (D) OTHER INFORMATION: / Ceres Seq. ID 2029225
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 408: agggattcta gggctttcct tcattggtca gatcagacga cgttttacat cttcttcttc 60 ttcctcttcg atattcgtca gtgtgtgtat tttggggaaa actttgtgag caaagagcga 120 gaaaatgagc ggagccggta agaaaatcgc ggatgtggct ttcaaagctt caaggactat 180 cgattgggat ggtatggcta aggtccttgt cacagatgag gctcgtagag agttctctaa 240 ccttcgtcgt gctttcgatg aggttaacac acagctccag accaaattta gtcaggaacc 300 tgaacctata gattgggatt actataggaa gggtattgga gctggcattg ttgacaagta 360 caaggaagct tatgacagca ttgagattcc aaagtacgtt gacaaagtta ctcctgaata 420 caagccaaag tttgatgctt tgttggtgga actgaaagaa gcagaacaga aatcgctcaa 480 ggagtctgaa cggttggaga aagaaattgc tgatgtccaa gagatcagca aaaagctcag 540 caccatgact gcagatgagt actttgagaa gcacccggaa ctcaaaaaga agtttgatga 600 cgaaatccgt aatgacaact ggggatactg atcatgtttc tccatctccg gcttggaaag 660 aaaactctct ttctctttct ctgttctctt actgtgattt tgtgagccaa tcataacaat 720 aataagtaca ccattcactt aagcagtgtt gagatcttca ttccaaggaa gataaacgca 780 tttggtt
■ 2 ) INFORMATION FOR SEQ ID NO: 09: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 168 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide !ix) FEATURE:
(A) NAME/KEY: peptiαe
(B) LOCATION: 1..168
(D) OTHER INFORMATION: / Ceres Seq. ID 2029226 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 409: Met Ser Gly Ala Gly Lys Lys He Ala Asp Val Ala Phe Lys Ala Ser 1 5 10 15
Arg Thr He Asp Trp Asp Gly Met Ala Lys Val Leu Val Thr Asp Glu
20 25 30
Ala Arg Arg Glu Phe Ser Asn Leu Arg Arg Ala Phe Asp Glu Val Asn
35 40 45
Thr Gin Leu Gin Thr Lys Phe Ser Gin Glu Pro Glu Pro He Asp Trp
50 55 60
Asp Tyr Tyr Arg Lys Gly He Gly Ala Gly He Val Asp Lys Tyr Lys
65 70 75 80
Glu Ala Tyr A.sp Ser He Glu He Pro Lys Tyr 'al Asp Lys Val Thr
85 90 95
Pro Glu Tyr Lys Pro Lys Phe A.sp Ala Leu Leu Val Glu Leu Lys Glu
100 105 110
Ala Glu Gin Lys Ser Leu Lys Glu Ser Glu Arg Leu Glu Lys Glu He
115 120 125
Ala Asp Val Gin Glu He Ser Lys Lys Leu Ser Thr Met Thr Ala Asp
130 135 140
Glu Tyr Phe Glu Lys His Pro Glu Leu Lys Lys Lys Phe Asp Asp Glu 145 ' 150 155 160
He Arg Asn A.sp Asn Trp Gly Tyr 165
(2) INFORMATION FOR SEQ ID NO: 410:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 145 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..145
(D) OTHER INFORMATION: / Ceres Seq. ID 2029227 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 410: Met Ala Lys Val Leu Val Thr Asp Glu Ala Arg Arg Glu Phe Ser Asn 1 5 10 15
Leu Arg Arg Ala Phe Asp Glu Val Asn Thr Gin Leu Gin Thr Lys Phe 20 25 30
Ser Gin Glu Pro Glu Pro He Asp Trp Asp Tyr Tyr Arg Lys Gly He
35 40 45
Gly Ala Gly He Val Asp Lys Tyr Lys Glu Ala Tyr Asp Ser He Glu
50 55 " 60
He Pro Lys Tyr Val Asp Lys Val Thr Pro Glu Tyr Lys Pro Lys Phe 65 70 75 80
A.sp Ala Leu Leu Val Glu Leu Lys Glu Ala Glu Gin Lys Ser Leu Lys
85 90 95
Glu Ser Glu He Ser
Lys Lys Leu Ser Thr Met Thr Ala Asp Glu Tyr Phe Glu Lys His Pro
115 120 * 125
Glu Leu Lys Lys Lys Phe A.sp Asp Glu He Arg Asn A.sp A.sn Trp Gly
130 135 140
Tyr 145 , INFORMATION FOR SEQ ID NO: 411: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1587 base pairs
(B) TYPE: nucleic acid
(C) S STTRRAANNDDEEDDNNEESSSS:: sinαle
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/ KEY:
(B) LOCATION: 1..1587
(D) OTHER INFORMATION: / Ceres Seq. ID 2029422 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 411: gtagtctctc tttttataac cacttctcga aaactgaaac ctttgtagag agaacccata 60 gttcgataaa acattctttt tgcaactgag acttggcaac ttggttttac tcaaagtaag 120 atttcttctt gttgatggtg ataagttcaa tatgatgaaa agtttggcta gtgcggttgg 180 agggaagacg gcgagggcat gtgatagctg cgtgaagagg cgggcacgtt ggtattqcgc 240 agctgatgat gcctttcttt gccatgcttg tgacggttcg gtccactcgg caaaccctct 300 tgctcgtagg cacgagagag ttcgcttgaa atcggctagc gccggaaagt atcgccatgc 360 ctcgccgcct caccaagcca cgtggcatca gggatttaca cgtaaagctc ggaccccacg 420 tggaggcaag aagagccaca cgatggtttt tcatgatctt gtgccggaga tgagcacgga 480 ggatcaagcg gagagttacg aggtggaaσa gcagctcata tttgaggtgc cggtgatgaa 540 ctcgatggtt gaggagcaat gctttaacca atccctggag aaacagaatg agtttccaat 600 gatgccctta agtttcaaga gtagtgacga agaagatgac gacaacgctg agagttgtct 660 gaatggtttg ttcccaaccg acatggaact agctcagttc acagctgacg tggagactct 720 actcggtgga ggggatcgag agtttcattc catagaagaa ctagggttag gtgagatgtt 780 aaagatcgaa aaagaggagg tggaggaaga gggagttgtg acaagagaag tgcatgatca 840 agatgaaggt gatgagacat ccccatttga aataagcttt gactacgagt acacacacaa 900 gaccacattc gatgaaggag aagaagatga gaaagaagac gtgatgaaga atgtgatgga 960 gatgggagtg aatgagatga gtggtgggat taaagaagag aagaaggaga aggctcttat 1020 gcttagattg gactatgaat cagtcatttc cacttgggga ggccaaggga tcccatggac 1080 cgcccgggtg ccatctgaaa tagacctcga catggtttgt ttcccaaccc ataccatggg 1140 tgaaagtgga gcagaggctc atcatcacaa ccacttccgc ggcctagggt tacacctagg 1200 agatgctggg gatggaggaa gagaggctag ggtttcaaga taccgagaga aaaggaggac 1260 aaggttgttc tccaagaaga taaggtacga ggtacgtaaa ttgaatgcag agaaaaggcc 1320 tcgcatgaaa ggaaggttcg tcaagagatc ttcaattggt gttgctcact aaagaactta 1380 attaattatg gatattaaat tactttgctc tcatcttgct tttttgttgc tatagttttg 1440 gtgattgtta gctttctttt tctgcattca tagagaattt tgcacgtttt tgtgagctac 1500 gtatgtacat aaatatatca ccaaaaaatg tgactatctt gtaagcactg atttatatag 1560 tcgatataac gtgaattttg attgctg (2) INFORMATION FOR SEQ ID NO: 412: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 406 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..406 (D) OTHER INFORMATION: / Ceres Seq. ID 2029423
.xi) SEQUENCE DESCRIPTION: SEQ ID NO:412: Met Met Lys Ser Leu Ala Ser Ala Val Gly Gly Lys Thr Ala Arg Ala 1 5 10 15
Cys Asp Ser Cys Val Lys Arg Arg Ala Arg Trp Tyr Cys Ala Ala Asp 20 25 30
Asp Ala Phe Leu Cys His Ala Cys A.sp Gly Ser Val His Ser Ala Asn
35 40 45
Pro Leu Ala A.rg Arg His Glu A.rg Val Arg Leu Lys Ser Ala Ser Ala 50 55 60 Gly Lys Tyr Arg His Ala Ser Pre Pro His Gin Ala Thr Trp His Gin 65 70 75 80
Gly Pne Thr Arg Lys Ala Arg Thr Pro Arg Gly Gly Lys Lys Ser His
85 90 " 95
Thr Met Val Phe His Asp Leu Val Pro Glu Met Ser Thr Glu Asp Gin 100 " 105 110
Ala Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro Val
115 12C 125
Met A.sn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys
130 135 140 Gin Asn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser Asp Glu
145 150 155 160
Glu Asp A.sp A.sp Asn Ala Glu Ser Cys Leu A.sn Gly Leu Phe Pro Thr
165 170 175
Asp Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly 180 185 190
Gly Gly A.sp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu
195 200 205
Met Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Gly Val Val Thr
210 215 220 Arg Glu Val His Asp Gin Asp Glu Gly A.sp Glu Thr Ser Fro Phe Glu
225 230 235 240
He Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu Gly
245 250 255
Glu Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met Gly 260 " 265 " 2"O
Val Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys Ala
275 280 285
Leu Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly Gly
290 295 300 Gin Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu Asp
305 310 315 320
Met Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu Ala
325 330 335
His His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly Asp Ala 340 345 350
Gly Asp Gly Gly Arg Glu Ala A.rg Val Ser Arg Tyr Arg Glu Lys Arg
355 " 360 365
Arg Thr A.rg Leu Phe Ser Lys Lys He Arg Tyr Glu Val A.rg Lys Leu 370 " 375 380 Asn Ala Glu Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys Arg Ser 385 390 395 " 400
Ser He Gly Val Ala His
405 (2) INFORMATION FOR SEQ ID NO: 413: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 405 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..405
(D) OTHER INFORMATION: / Ceres Seq. ID 2029424 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:413: Met Lys Ser Leu Ala Ser Ala Val Gly Gly Lys Thr Ala A.rg Ala Cys 1 5 10 15
Asp Ser Cys Val Lys A.rg Arg Ala A.rg Trp Tyr Cys Ala Ala A.sp Asp
20 25 30
Ala Phe Leu Cys His Ala Cys Asp Gly Ser Val His Ser A a Asn Pro 35 40 45 Leu Ala Arg Arg His Glu Arg Val A.rg Leu Lys Ser Ala Ser A.la Gly 50 55 60
Lys Tyr Arg His Ala Ser Pro Pro His Gin Ala Thr Trp His Gin Gly 65 70 75 " 80~
Phe Thr Arg Lys Ala Arg Thr Pro Arg Gly Gly Lys Lvs Ser His Thr 85 ' 90^ 95
Met Val Phe Gin Ala
Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro al Met 115 120 125 Asn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys Gin 130 135 140
Asn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser A.sp Glu Glu 145 150 155 160
Asp Asp Asp A.sn Ala Glu Ser Cys Leu Asn Gly Leu Phe Pro Thr Asp 165 170 175
Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly Gly
180 185 190
Gly Asp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu Met 195 200 205 Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Gly Val Val Thr Arg 210 215 220
Glu Val His Asp Gin Asp Glu Gly Asp Glu Thr Ser Pro Phe Glu He 225 230 235 240
Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu Gly Glu 245 250 ' 255
Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met Gly Val
260 265 270
Asn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys Ala Leu 275 280 285 Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly Gly Gin 290 295 300
Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu Asp Met 305 310 315 ' 320
Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu Ala His 325 330 335
His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly A.sp A.la Gly
340 345 350
Asp Gly Gly Arg Glu Ala Arg Val Ser Arg Tyr Arg Glu Lys Arg Arg 355 360 365 Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg Lys Leu Asn 370 375 380
Ala Glu Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys Arg Ser Ser 385 ' ' 390 395 " 400
He Gly Val Ala His 405
(2) INFORMATION FOR SEQ ID NO: 414: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 309 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..309
(D) OTHER INFORMATION: / Ceres Seq. ID 2029425 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 414:
Met Val Phe His Asp Leu Val Pro Glu Met Ser Thr Glu Asp Gin Ala 1 5 10 15
Glu Ser Tyr Glu Val Glu Glu Gin Leu He Phe Glu Val Pro Val Met 20 25 30 Asn Ser Met Val Glu Glu Gin Cys Phe Asn Gin Ser Leu Glu Lys Gin 35 40 45
A.sn Glu Phe Pro Met Met Pro Leu Ser Phe Lys Ser Ser A.sp Glu Glu
50 55 60
A.sp Asp Asp Asn Ala Glu Ser Cys Leu A.sn Gly Leu Pr.e Pro Thr Asp 65 70 75 80
Met Glu Leu Ala Gin Phe Thr Ala Asp Val Glu Thr Leu Leu Gly Gly
85 90 35
Gly Asp Arg Glu Phe His Ser He Glu Glu Leu Gly Leu Gly Glu Met 100 105 110 Leu Lys He Glu Lys Glu Glu Val Glu Glu Glu Gly Val Val Thr Arg 115 120 125
Glu Val His Asp Gin Asp Glu Gly Asp Glu Thr Ser Fro Phe Glu He
130 135 140
Ser Phe Asp Tyr Glu Tyr Thr His Lys Thr Thr Phe Asp Glu Gly Glu 145 150 155 " 160
Glu Asp Glu Lys Glu Asp Val Met Lys Asn Val Met Glu Met Gly Val
165 170 175
A.sn Glu Met Ser Gly Gly He Lys Glu Glu Lys Lys Glu Lys Ala Leu 180 185 190 Met Leu Arg Leu Asp Tyr Glu Ser Val He Ser Thr Trp Gly Gly Gin 195 200 205
Gly He Pro Trp Thr Ala Arg Val Pro Ser Glu He Asp Leu Asp Met
210 215 220
Val Cys Phe Pro Thr His Thr Met Gly Glu Ser Gly Ala Glu A.la His 225 230 235 240
His His Asn His Phe Arg Gly Leu Gly Leu His Leu Gly A.sp Ala Gly
245 250 " 255
Asp Gly Gly A.rg Glu Ala Arg Val Ser A.rg Tyr Arg Glu Lys Arg A.rg 260 265 270 Thr Arg Leu Phe Ser Lys Lys He Arg Tyr Glu Val Arg Lys Leu A.sn 275 280 285
Ala Glu Lys Arg Pro Arg Met Lys Gly Arg Phe Val Lys A.rg Ser Ser
290 295 300
He Gly Val Ala His 305
(2) INFORMATION FOR SEQ ID NO: 415: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1300 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..1300
(D) OTHER INFORMATION: / Ceres Seq. ID 2029806 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 415: ctcaagtttc ttgcaattac ctacttacaa caaagcaact cgactcgaac aaacacatcc 60 atggctcctt ctgcgcaacc tcttcctgtg agtgtttcgg atgaaaaata tgcgaatgtc 120 aagtgggaag agttggcatt caagtttgtt cgtacggatt atatgtatgt tgcgaagtgc 180 aatcatggag agagttttca agaggggaag attcttcctt ttgctgattt gcaacttaac 240 ccttgcgctg ctgttcttca gtatggccag ggtttatatg aaggactgaa agcttacagg 300 acagaagatg gtcggattct gctattccga ccagaccaaa acggtctccg ccttcaagcc 360 ggagctgaca gactctatat gccttatcct tcggtcgatc aattcgtctc cgccatcaaa 420 caagttgctc ttgccaacaa gaaatggatt cctcctccgg ggaaaggaac attgtatatt 480 aggcctatct tgtttgggag tggtccgatt cttggttcat ttcccattcc tgagaccacc 540 ttcacagctt ttgcctgtcc tgttggacgt tatcataagg ataactctgg tttgaatctg 600 aaaatcgaag atcagtttcg tcgagcttt cctagtggaa ctggtggtgt gaagagcatc 660 acaaactatt gtcctgtttg gataccattg gcagaggcga aaaaacaagg tttctctgat 720 attttgtttt tggatgctgc aactggcaaa aacattgaag aacttttcgc agctaatgtt 780 tttatgctca agggcaatgt tgtatcgaca ccaacaattg caggaactat tttgcccgga 840 gtcactcgaa actgcgtaat ggaattgtgt cgtgatttcg gctaccaggt cgaggaacgt 900 acσattcctc tagtggactt tctcgatgcg gacgaagctt tctgtactgg cactgcttcc 960 attgtgacta gtattgcatc cgtaacct t aaagacaaaa agaccggatt caaaacaggg 1020 gaagaaacat tggctgcgaa gctatacgaa acgttaagtg at tccagac gggtcgggtc 1080 gaggatacca agggatggac ggtggagatt gaccgccagg ctgaaagtt gaaactgtaa 1140 cttgatgcta aatatgtgtg tgtgtgtata caaaacttat taagaaaca tctgaagatg 1200 tctctgatct ttgtgattgt gatgatcatg catgtcctat gttgcgatg tattttataa 1260 atgttcgtct gtaagttatt taataactae ggcttt tgc ,2) INFORMATION FOR SEQ ID NO: 416: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 374 amir.e acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptiae (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..374 (D) OTHER INFORMATION: / Ceres Seq. ID 202980:
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 416: Leu Lys Phe Leu Ala He Thr Tyr Leu Gin Gin Ser Asn Ser Thr Arg 1 5 10 15
Thr A.sn Thr Ser Met A.la Pro Ser Ala Gin Pro Leu Pro Val Ser Val 20 25 30
.er ASP Glu Lys Tyr Ala Asn vs T: ueu _-._a Phe Lys 35 40 45
Phe Val Arg Thr A.sp Tyr Met Tyr Val Ala JVS A.sn His Gly Glu
50 55 60
Ser Phe Gin Glu Gly Lys He Leu Pre Phe Ala Asp Leu .In Leu Asn 65 70 75 80
Pro Cys Ala Ala Val Leu Gin Tyr Gly Gin Gly Leu Tyr Glu Gly Leu
85 90 95
Lys A.la Tyr Arg Thr Glu Asp Gly Arg He Le 5iu Leu Phe A.rg Pro A.sp
100 105 πό
Gin Asn Gly Leu Arg Leu Gin Ala Gly Ala A.sp Arg Leu Tyr Met Pro
115 120 125 Tyr Pro Ser Val Asp Gin Phe Val Ser Ala He Lys Gin Val A.la Leu 130 135 140
Ala Asn Lys Lys Trp He Pro Pro Pro Gly Lys Glv Thr Leu Tyr He 145 150 155 160
Arg Pro He Leu Phe Gly Ser Gly Pro He Leu Gly Ser Phe Pro He
165 170 175
Pro Glu Thr Thr Phe Thr Ala Phe Ala Cys Pro /al Gly Arg Tyr His
180 185 190
Lys Asp Asn Ser Gly Leu Asn Leu Lys He Glu -.sp Gin Phe Arg Arg
195 200 205
Ala Phe Pro Ser Gly Thr Gly Gly Val Lys Ser He Thr Asn Tyr Cys 210 215 220 Pro Val Trp He Pro Leu Ala Glu Ala Lys Lys Gin Gly Phe Ser Asp
225 230 235 240
He Leu Phe Leu Asp Ala Ala Thr Gly Lys Asn He Glu Glu Leu Phe
245 250 255 Ala Ala Asn Val Phe Met Leu Lys Gly Asn Val Val Ser Thr Pro Thr
260 265 270
He Ala Gly Thr He Leu Pro Gly Val Thr Arg Asn Cys Val Met Glu
275 280 285
Leu Cys Arg A.sp Phe Gly Tyr Gin Val Glu Glu Arg Thr He Pro Leu 290 295 300
Val Asp Phe Leu Asp Ala A.sp Glu Ala Phe Cys Thr Gly Thr A.la Ser
305 " 310 315 320
He Val Thr Ser He Ala Ser Val Thr Phe Lys Asp Lys Lys Thr Gly
325 330 335 Phe Lys Thr Gly Glu Glu Thr Leu Ala Ala Lys Leu Tyr Glu Thr Leu
340 345 350
Ser Asp He Gin Thr Gly Arg Val Glu Asp Thr Lys Gly Trp Thr Val
355 360 " 365
Glu He Asp Arg Gin Gly 370
,2) INFORMATION FOR SEQ ID NO: 417: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 354 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear , ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..354
(D) OTHER INFORMATION: / Ceres Seq. ID 2029808 ;xi) SEQUENCE DESCRIPTION: SEQ ID NO: 417: Met Ala Pro Ser Ala Gin Pro Leu Pro Val Ser Val Ser A.sp Glu Lys 1 5 10 15 Tyr Ala Asn Val Lys Trp Glu Glu Leu Ala Phe Lys Phe Val Arg Thr 20 25 " 30
Asp Tyr Met Tyr Val Ala Lys Cys Asn His Gly Glu Ser Phe Gin Glu
35 40 45
Gly Lys He Leu Pro Phe Ala Asp Leu Gin Leu Asn Pro Cvs Ala A.la 50 55 60
Val Leu Gin Tyr Gly Gin Gly Leu Tyr Glu Gly Leu Lys Ala Tyr Arg
65 70 75 8θ"
Thr Glu Asp Gly Arg He Leu Leu Phe Arg Pro A.sp Gin A.sn Gly Leu
85 90 95 Arg Leu Gin Ala Gly Ala Asp Arg Leu Tyr Met Pro Tyr Pro Ser Val
100 105 110
A.sp Gin Phe Val Ser Ala He Lys Gin Val Ala Leu A.la Asn Lys Lys
115 120 125
Trp He Pro Pro Pro Gly Lys Gly Thr Leu Tyr He Arg Pro He Leu 130 135 140
Phe Gly Ser Gly Pro He Leu Gly Ser Phe Pro He Pro Glu Thr Thr
145 150 155 160
Phe Thr Ala Phe A.la Cys Pro Val Gly Arg Tyr His Lys Asp Asn Ser
165 170 175 Gly Leu Asn Leu Lys He Glu Asp Gin Phe Arg Arg Ala Phe Pro Ser
180 185 190
Gly Thr Gly Gly Val Lys Ser He Thr Asn Tyr Cys Pro Val Trp He
195 200 205
Pro Leu Ala Glu Ala Lys Lys Gin Gly Phe Ser Asp He Leu Phe Leu 210 215 220
Asp Ala Ala Thr Gly Lys A.sn He Glu Glu Leu Phe Ala Ala Asn Val 225 230 235 240 Phe Met Leu Lys Gly Asn Val Val Ser Thr Pro Thr He Ala Gly Thr
245 250 255
He Leu Pro Gly Val Thr Arg Asn Cys Val Met Glu Leu Cys Arg Asp 260 265 270 Phe Gly Tyr Gin Val Glu Glu Arg Thr He Pro Leu Val Asp Phe Leu 275 280 285
Asp Ala Asp Glu Ala Phe Cys Thr Gly Thr Ala Ser He Val Thr Ser
290 295 300
He Ala Ser Val Thr Phe Lys Asp Lys Lys Thr Gly Phe Lys Thr Gly 305 310 315 320
Glu Glu Thr Leu Ala Ala Lys Leu Tyr Glu Thr Leu Ser Asp He Gin
325 330 335
Thr Gly Arg Val Glu Asp Thr Lys Gly Trp Thr Val Glu He Asp Arg 340 345 350 Gin Gly
(2) INFORMATION FOR SEQ ID NO: 418: (i) SEQUENCE CHARACTERISTICS:
W ) LENGTH: 320 amino acids (B) TYPE: amino acid
,C) STRANDEDNESS: >D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: <A) NAME/KEY: peptide
(B) LOCATION: 1..320
.D) OTHER INFORMATION: / Ceres Seq. ID 2029809 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 418: Met Tyr Val Ala Lys Cys Asn His Gly Glu Ser Phe Gin Glu Gly Lys 1 5 10 15
He Leu Pro Phe Ala Asp Leu Gin Leu Asn Pro Cys Ala A.la Val Leu
20 25 30
Gin Tyr Gly Gin Gly Leu Tyr Glu Gly Leu Lys Ala Tyr Arg Thr Glu 35" 40 45 Asp Gly Arg He Leu Leu Phe Arg Pro Asp Gin Asn Gly Leu Arg Leu 50 55 60
Gin Ala Gly Ala Asp Arg Leu Tyr Met Pro Tyr Pro Ser Val Asp Gin 65 " 70 "5 80
Phe Val Ser Ala He Lys Gin Val Ala Leu Ala Asn Lys Lys Trp He 85 90 95"
Pro Pro Pro Gly Lys Gly Thr Leu Tyr He Arg Pro He Leu Phe Gly
100 105 110
Ser Gly Pro He Leu Gly Ser Phe Pro He Pro Glu Thr Thr Phe Thr 115 120 125 Ala Phe Ala Cys Pro Val Gly Arg Tyr His Lys Asp Asn Ser Gly Leu 130 135 140
Asn Leu Lys He Glu Asp Gin Phe Arg Arg Ala Phe Pro Ser Gly Thr 145 " 150 155 160
Gly Gly Val Lys Ser He Thr Asn Tyr Cys Pro Val Trp He Pro Leu 165 170 175
Ala Glu Ala Lys Lys Gin Gly Phe Ser Asp He Leu Phe Leu A.sp Ala
180 185 190
Ala Thr Gly Lys Asn He Glu Glu Leu Phe Ala Ala Asn Val Phe Met 195 200 205 Leu Lys Gly Asn Val Val Ser Thr Pro Thr He Ala Gly Thr He Leu 210 " 215 220
Pro Gly Val Thr Arg Asn Cys Val Met Glu Leu Cys Arg Asp Phe Gly 225 230 235 240
Tyr Gin Val Glu Glu Arg Thr He Pro Leu Val Asp Phe Leu A.sp Ala " 245 250 255
Asp Glu A.la Phe Cys Thr Gly Thr Ala Ser He Val Thr Ser He Ala 260 265 270 Val Thr Phe Lys Asp Lys Lys Thr Gly Phe Lys Thr Gly Glu Glu 275 280 285
Thr Leu Ala Ala Lys Leu Tyr Glu Thr Leu Ser Asp He Gin Thr Gly
290 295 300
Arg Val Glu Asp Thr Lys Gly Trp Thr Val Glu He Asp Arg Gin Gly
305 310 315 320 INFORMATION FOR SEQ ID NO: 419:
:'i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 987 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: .inear MOLECULE TYPE: DNA .genomic)
(ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: .98"
(D) OTHER INFORMATION: / Ceres Seq. ID 2030038
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 419: atatctaaaa αactcaaaaa cctatcσtca tttatcttca aggcggaa taacggagat 60 ggccσccatt acagctctca ctctccgctc tcctgtttat ctcccatcat ctgccacaag 120 cectagattc catggcttca ccaateaacc accaccagct cgtctcttct ttectcttaa 180 ccccttccct tctctatcaa tccaaaaccc taaatccatc egaatttccg catccσcttc 240 αccαataaca acaccaatcc tccaαacqqa qaaqtcaaca gctcggtcat cgacactcac 200 cgggtccact cggtctctcg ctactctcgc ggctttagca atcgctgtaa ccagagtcct 360 agctcagaaa ctctctctcg caatccagac ttcaagtccc gtaatcgccg acgggttacg 420 attctctctc agtaccgccg gacctgtctt cttcgcgtct ctccgggatc gtcctccggg 480 atacttgaac acgccgctga cggttgttgc ggtggggata aagaagtggc tagacattta 540 cagtggggta ttgatggtta gggttttgct gagttggttc cctaatatcc cttgggaaag 600 acagcctttg tctgccatta gagatctctg tgatccttac ttgaatctct tcagaaacat 660 cattcctcct atcttcgata cgcttgatgt tagtccattg cttgctttcg cggttcttgg 720 tacacttgga tcgattgttc atggcagcac tgggtagaaa ttggaagact tgagctaatg 780 gttttgttga aacgttcaat tgggaaattt ctgcaacttg tttcccaaga ttagggaaaa 840 atcagaattt gatgctgtgt tggatgctcg atgagagttg tgagctt at cgtttttgtt 900 gttctctttt tgactttgat tctgaataat gagattttgg gttgttgttt atctcctaat 960 tacatgttca gactaccgtt tattgat (2) INFORMATION FOR SEQ ID NO:420:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 251 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptiαe
(B) LOCATION: 1..251 (D) OTHER INFORMATION: Ceres Seo. ID 2030039 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 420:
:yr Leu Lys Asp Ser Lys Thr Tyr Arg His Leu Ser Ser Thr Gly Gly
10 15
He Thr Glu Met Ala Ala He Thr Ala Leu Thr Leu A.ro Ser Pro Val
25 30
Tyr Leu Pro Ser Ser Ala Thr Ser Pro Arg Phe His Gly Phe Thr Asn
35 40 45*
Gin Pro Pro Pro Ala Arg Leu Phe Phe Pro Leu A.sn Pro Phe Pro Ser
50 " 55 60
Leu Ser He Gin Asn Pro Lys Ser He Arg He Ser Ala Ser Ala Ser 65 70 75 80
Pro He Thr Thr Pro He Leu Gin Thr Glu Lys Ser Thr A.la Arg Ser
85 90 95
Ser Thr Leu Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu A.la Ala Leu
100 105 110
Ala He A.la Val Thr Arg Val Leu Ala Gin Lys Leu Ser Leu A.la He 115 120 125
Gin Thr Ser Ser Pro Val He Ala Asp Gly Leu Arg Phe Ser Leu Ser
130 135 140
Thr Ala Gly Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro Pro Gly 145 150 155 160
Tyr Leu Asn Thr Pro Leu Thr Val Val Ala Val Gly He Lys Lys Trp
165 170 175
Leu Asp He Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu Ser Trp 180 185 190 Phe Pro Asn He Pro Trp Glu Arg Gin Pro Leu Ser Ala He Arg Asp 195 200 205
Leu Cys Asp Pro Tyr Leu Asn Leu Phe Arg Asn He He Pro Pro He
210 215 220
Phe Asp Thr Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val Leu Gly 225 230 235 240
Thr Leu Gly Ser He Val His Gly Ser Thr Gly
245 250
(2) INFORMATION FOR SEQ ID NO: 421: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 232 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..232
(D) OTHER INFORMATION: / Ceres Seq. ID 2030040 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 421: Met Ala Ala He Thr Ala Leu Thr Leu Arg Ser Pro Val Tyr Leu Pro 1 5 10 15
Ser Ser Ala Thr Ser Pro Arg Phe His Gly Phe τhr Asn Gin Pro Pro
20 25 30
Pro Ala Arg Leu Phe Phe Pro Leu Asn Pro Phe Pro Ser Leu Ser He 35 40 45
Gin Asn Pro Lys Ser He Arg He Ser Ala Ser Ala Ser Pro He Thr
50 55 60
Thr Pro He Leu Gin Thr Glu Lys Ser Thr Ala Arg Ser Ser Thr Leu 65 70 75 80 Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu Ala Ala Leu Ala He Ala
85 90 95
Val Thr Arg Val Leu Ala Gin Lys Leu Ser Leu Ala He Gin Thr Ser
100 105 110
Ser Pro Val He Ala Asp Gly Leu Arg Phe Ser Leu Ser Thr Ala Gly 115 120 125
Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro Pro Gly Tyr Leu Asn
130 135 140
Thr Pro Leu Thr Val Val Ala Val Gly He Lys Lys Trp Leu Asp He 145 150 155 160 Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu Ser Trp Phe Pro Asn
165 170 175
He Pro Trp Glu Arg Gin Pro Leu Ser Ala He A.rg Asp Leu Cys Asp
180 185 190
Pro Tyr Leu Asn Leu Phe Arg Asn He He Pro Pro He Phe Asp Thr 195 200 205
Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val Leu Gly Thr Leu Gly
210 215 220
Ser He Val His Gly Ser Thr Gly 225 230 (2) INFORMATION FOR SEQ ID NO: 422: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 755 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..755
(D) OTHER INFORMATION: / Ceres Seq. ID 203177 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 422: ccgcagaaaa ccctattgct cccctttgct caagctcagt gcctctttgc agcgaaagct 60 caaccaacaa gacgatgatt atctcagaga acaatcgcag agagatctgc aaataccttt 120 tcaaagaggg agtatgcttt gctaagaagg atttcaatct cccaaagcat ccgttgattg 180 atgtaccaaa cctgcaagtg attaagctca tgcagagttt caagtccaag gagtacgtta 240 gggagacatt tgcgtggatg cattattatt ggtttctgac taatgaagga attgagttct 300 tgagaactta tcttaacctt ccttccgatg ttgtccctgc tactttgaag aagtctgcta 360 agcccggtgg tcgtcccttt ggtggcccac ctggtgatcg ccaaagagga ccacctcgct 420 ctgatggaga ccgtcccaga tttggtgacc gtgatggata ccgtggaggc ccacgtggtg 480 gtgatgagaa gggtggagct ccagctgatt tccagccgtc tttccaagga ggtggtggta 540 ggcctggttt tggccgtggt gcaggcggtt acagtgcagc agcaccatct ggttcagggt 600 tcccttgaaa aatttgttgt catattgcga cgatggaagg acagttttgt tttttgttct 660 agttctgttt gtgtaatgca aatctggaat ctataatcta tctattacct tcaccttggt 720 ttaaacgaac aaatcctgta gtttcaggat tagtg
(2) INFORMATION FOR SEQ ID NO: 423: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 201 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..201
(D) OTHER INFORMATION: / Ceres Seq. ID 2031779
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 23:
Ala Glu Asn Pro He Ala Pro Leu Cys Ser Ser Ser Val Pro Leu Cys
10 15
Ser Glu Ser Ser Thr Asn Lys Thr Met He He Ser Glu Asn Asn Arg
20 25 30
Arg Glu He Cys Lys Tyr Leu Phe Lys Glu Gly Val Cys Phe Ala Lys
35 40 45
Lys Asp Phe Asn Leu Pro Lys His Pre Leu He Asp Val Pro Asn Leu
50 55 60
Gin Val He Lys Leu Met Gin Ser Phe Lys Ser Lys Glu Tyr Val Arg
65 70 75 80
Glu Thr Phe Ala Trp Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly
85 90 95
He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro Ser Asp Val Val Pro
100 105 110
Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly Gly
115 120 125
Pro Pro Gly Asp Arg Gin Arg Gly Pro Pro Arg Ser Asp Gly Asp Arg
130 135 140
Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg Gly Gly Pro Arg Gly Gly 145 150 155 160
Asp Glu Lys Gly Gly Ala Pro Ala Asp Phe Gin Pro Ser Phe Gin Gly
165 170 175
Gly Gly Gly Arg Pro Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala
180 185 190
Ala Ala Pro Ser Gly Ser Gly Phe Pro
195 200
(2) INFORMATION FOR SEQ ID NO: 424: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 177 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..177
(D OTHER INFORMATION: / Ceres Seq. ID 2031780 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 424:
Met He He Ser Glu Asn A-;n A.rg Arg Glu He Cys Lys Tyr Leu Phe 1 5 10 15 Lys Glu Gly Val Cys Phe Ala Lys Lys Asp Phe A.sn Leu Pro Lys His 20 25 30 Pro Leu He Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser 35 40 " 45
Phe Lys Ser Lys Glu Tyr Val A.rg Glu Thr Phe Ala Trp Met His Tyr
50 55 60
Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu 65 70 75 80
A.sn Leu Pre Ser A.sp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys
85 90 95
Pro Gly Gly A.rg Pro Phe Gly Gly Pro Pro Gly A.sp A.rg GIr. Arg Gly 100 105 110 Pro Pro Arg Ser Asp Gly Asp Arg Pro A.rg Phe Gly A.sp A.rg Asp Gly 115 120 125
Tyr Arg Gly Gly Pro Arg Gly Gly Asp Glu Lys Gly Gly Ala Pro Ala
130 * 135 140
Asp Phe Gin Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro Gly Phe Gly 145 150 155 160
Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser Gly Phe
165 170 175
Pro (2) INFORMATION FOR SEQ ID NO: 425: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 132 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..132 (D) OTHER INFORMATION: / Ceres Seq. ID 2031781
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 425:
Met Gin Ser Phe Lys Ser Lys Glu Tyr Val A.rg Glu Thr Phe Ala Trp 1 5 10 15
Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg 20 25 " 30
Thr Tyr Leu A.sn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys
35 40 45
Ser Ala Lys Pro Gly Gly A.rg Pro Phe Gly Gly Pro Pro Gly Asp A.rg 50 55 60 Gin Arg Gly Pro Pro Arg Ser Asp Gly Asp Arg Pro Arg Phe Gly Asp 65 70 75 80
Arg Asp Gly Tyr Arg Gly Gly Pro Arg Gly Gly Asp Glu Lys Gly Gly
85 90 95'
Ala Pro Ala Asp Phe Gin Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro 100 105 110
Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala A.la Ala Pro Ser Gly 115 120 125 Ser Gly Phe Pro
130 (2) INFORMATION FOR SEQ ID NO: 426: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 538 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic, , ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..538
(D) OTHER INFORMATION: / Ceres Seq. ID 2032723 ixi) SEQUENCE DESCRIPTION: SEQ ID NO: 426: aaagcaataa aaaacaaaaa tggcgtttac tccgaagatc atcacatgcc tcattgtcct 60 tacgatctac atggcatccc caacagagtc aaccatccag tgtgggacag tgacgagcac 120 actggcacag tgcctgacct acttgaccaa cagtggtcca ttgccatcac aatgctgcgt 180 gggagtcaag tcattgtacc aattggctca gaccacaccg gaccgtaaac aagtatgtga 240 gtgccttaaa ctagcgggta aagaaatcaa gggcctcaac accgaccttg tggccgcact 300 tcctaccact tgtggtgttt caattcccta ccccatcagt tttagcacca attgcgacag 360 tatatcgact gccgtgtgaa agaggctagt gatcagatgt acgactaatc aaacttgcca 420 gcttttaacc taattaaata aaagtattct gcttatattt cccattttat oattttatct 480 tcttatctat gtaaccacac gatttcatat gctaataat acaacggatc tttctctc i 2) INFORMATION FOR SEQ ID NO: 427: ;i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 119 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..119
(D) OTHER INFORMATION: / Ceres Seq. ID 2032724 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 427: r He
T\ -7r Met Ala Ser Pro Thr Glu Ser Thr He Gin Cys Gly Thr Val Thr 20 25 30 Ser Thr Leu Ala Gin Cys Leu Thr Tyr Leu Thr Asn Ser Gly Pro Leu 35 40 45
Pro Ser Gin Cys Cys Val Gly Val Lys Ser Leu Tyr Gin Leu Ala Gin
50 55 60
Thr Thr Pro Asp Arg Lys Gin Val Cys Glu Cys Leu Lys Leu Ala Gly 65 70 75 80
Lys Glu He Lys Gly Leu Asn Thr Asp Leu Val Ala A.la Leu Pro Thr
85 90 95
Thr Cys Gly Val Ser He Pro Tyr Pro He Ser Phe Ser Thr Asn Cys 100 105 110 Asp Ser He Ser Thr Ala Val 115 (2) INFORMATION FOR SEQ ID NO: 428: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..102
(D) OTHER INFORMATION: / Ceres Seq. ID 2032725 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 428: Met Ala Ser Pro Thr Glu Ser Thr He Gin Cys Gly Thr Val Thr Ser 1 5 10 15
Thr Leu Ala Gin Cys Leu Thr Tyr Leu Thr Asn Ser Gly Pro Leu Pro 20 25 30
Ser Gin Cys Cys Val Gly Val Lys Ser Leu Tyr Gin Leu Ala Gin Thr
35 40 45
Thr Pro Asp .-_rg Lys Gin Val Cys Glu Cys Leu Lys Leu Ala Gly Lys 50 55 60 Glu He Lys Gly Leu Asn Thr Asp Leu Val Ala Ala Leu Pro Thr Thr 65 70 75 80
Cys Gly Val Ser He Pro Tyr Pro He Ser Phe Ser Thr Asn Cys Asp
85 90 95
Ser He Ser Thr Ala Val 100
'2) INFORMATION FOR SEQ ID NO: 429: (ι) SEQUENCE CHARACTERISTICS:
.A) LENGTH: 75 amino acids C^ STRANDEDNESS:
C TOPOLOGY: linear ii1 MCLSCULE TYPE: peptiαe i ix) FEATURE:
A NAME/KEY: peptiαe B^ LOCATION: 1.. ~< 5
,:} OTHER INFORMATION: / Ceres Seq. ID 2032726 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 429: Lys Ala He Lys Asn Lys Asn Gly Val Tyr Ser Glu Asp His His Met 1 5 10 15 Pro His Cys Pro Tyr Asp Leu His Gly He Pro Asn Arg Val Asn His 20 25 30
Pro Val Trp Asp Ser Asp Glu His Thr Gly Thr Val Pro Asp Leu Leu
35~ 40 45
Asp Gin Glr Trp Ser He Ala He Thr Met Leu Arg Gly Ser Gin Val 50 55 60
He Val Pre He Gly Ser Asp His Thr Gly Pro 65 70 " 75
2, INFORMATION FOR SEQ ID NO: 430: .1) SEQUENCE CHARACTERISTICS: -.) LENGTH: 198 base pairs
TYPE: nucleic acid STRANDEDNESS: single Ω , TOPOLOGY: linear (11) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
,.-.! NAME/KEY: - 3) LOCATION: 1..198 ιD; OTHER INFORMATION: / Ceres Seq. ID 2035536 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 430: atgtcgttgg tatggttgga agcgatgttq cctctcggaa tcatcggtgg gatgctctgt 60 atcatgggca attctcagta ctacatccac aaagcttatc atggccgtcc taagcacatc 120 ggccacgatg aatgggatgt tgctatggaa agacgcgaca agaaagtcgt cgagaaagct 180 gcagctcctt ectcatga
(2) INFORMATION FOR SEQ ID NO: 431: (1) SEQUENCE CHARACTERISTICS:
,A) LENGTH: 65 ammo acids v3) TYPE: ammo acid vC) STRANDEDNESS: D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 2035537 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 431: Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Glv He He Gly 1 5 10 15
Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His Lys Ala
20 25 30
Tyr His Gly Arg Pro Lys His He Gly His Asp Glu Trp Asp Val Ala 35 40 45" Met Glu Arg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala Pro Ser 50 55 60
Ser 65
(2) INFORMATION FOR SEQ ID NO: 432: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 2035538 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 432:
Cys A.rg Trp Tyr Gly Trp Lys A.rg Cys Cys Leu Ser Glu Ser Ser Val 1 5 10 15
Gly Cys Ser Val Ser Trp Ala He Leu Ser Thr Thr Ser Thr Lys Leu 20 25 30 He Met Ala Val Leu Ser Thr Ser Ala Thr Met Asn Gly Met Leu Leu 35 40 45
Trp Lys Asp Ala Thr Arg Lys Ser Ser Arg Lys Leu Gin Leu Leu Pro
50 55 60
His 65
(2) INFORMATION FOR SEQ ID NO: 433: (1) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 57 ammo acids (C) STRANDEDNESS:
(D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..57
(D) OTHER INFORMATION: / Ceres Seq. ID 2035539 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 433: Met Leu Pro Leu Gly He He Gly Gly Met Leu Cys He Met Gly Asn 1 5 10 15 Ser Gin Tyr Tyr He His Lys Ala Tyr His Gly Arg Pro Lys His He
20 25 30
Gly His Asp Glu Trp Asp Val Ala Met Glu Arg Arg Asp Lys Lys Val
35 40 45
Val Glu Lys Ala Ala Ala Pro Ser Ser 50 55
(2) INFORMATION FOR SEQ ID NO: 434: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 573 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..573
(D) OTHER INFORMATION: / Ceres Seq. ID 2035575 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 434: atggagactt ctatgaggta taccagcaat tccaagtcta tgaagattca tgccaaagag 60 aaggttccgg tgaactcaaa aacccattta cagcttcatg gagagttaga tactggaact 120 ggggctccga gttacttctg tgcgatgatt agacactttt ttcctgaggc ttcaacaggc 180 cttggggtag gattgcatta tgataagcgc caaaagcttc ggtgtcttgt acgcggaaaa 240 aaagagtttc ctgtaagagc tgataagcgt gtaaccttta atattaaagg gcggtgtgat 300 attgatcagg acttaaatca gaagaacccc aaaggagcag cagaatttgc ctggaacata 360 atggatttca aggaagatca ggatgtacgg atcaaagttg gctacgaaat gtttgataag 420 gtcccttata tgcagattag agaaaacaat tggactctca acgcgaacat gaagggaaaa 480 tggaacttgc ggtatgacct gtaactgcat ttttttcaat catcatctga gaaatgtatt 540 gataccactg ctgatgaaca cattttaatt eta (2) INFORMATION FOR SEQ ID NO: 435: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 167 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..167
(D) OTHER INFORMATION: / Ceres Seq. ID 2035576 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 435: Met Glu Thr Ser Met Arg Tyr Thr Ser Asn Ser Lys Ser Met Lys He 1 5 10 15
His Ala Lys Glu Lys Val Pro Val Asn Ser Lys Thr His Leu Gin Leu
20 25 30
His Gly Glu Leu Asp Thr Gly Thr Gly Ala Pro Ser Tyr Phe Cys Ala
35 40 45
Met He Arg His Phe Phe Pro Glu Ala Ser Thr Gly Leu Gly Val Gly
50 55 60
Leu His Tyr Asp Lys Arg Gin Lys Leu Arg Cys Leu Val Arg Gly Lys 65 70 75 80
Lys Glu Phe Pro Val Arg Ala Asp Lys Arg Val Thr Phe Asn He Lys
85 90 95
Gly Arg Cys Asp He Asp Gin Asp Leu Asn Gin Lys Asn Pro Lys Gly
100 105 110
Ala Ala Glu Phe Ala Trp Asn He Met Asp Phe Lys Glu Asp Gin Asp
115 120 125
Val Arg He Lys Val Gly Tyr Glu Met Phe Asp Lys Val Pro Tyr Met
130 135 140
Gin He Arg Glu A.sn Asn Trp Thr Leu Asn Ala Asn Met Lys Gly Lys 145 150 155 160
Trp Asn Leu Arg Tyr Asp Leu
165 (2) INFORMATION FOR SEQ ID NO: 436: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 163 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..163
(D) OTHER INFORMATION: / Ceres Seq. ID 2035577 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 436: Met Arg Tyr Thr Ser Asn Ser Lys Ser Met Lys He His Ala Lys Glu 1 5 10 15
Lys Val Pro Val Asn Ser Lys Thr His Leu Gin Leu His Gly Glu Leu
20 25 30
Asp Thr Gly Thr Gly Ala Pro Ser Tyr Phe Cys Ala Met He Arg His 35 40 45
Phe Phe Pro Glu Ala Ser Thr Gly Leu Gly Val Gly Leu His Tyr A.sp
50 55 60
Lys Arg Gin Lys Leu Arg Cys Leu Val Arg Gly Lys Lys Glu Phe Pro 65 70 75 80 Val Arg Ala Asp Lys Arg Val Thr Phe Asn He Lys Gly Arg Cys Asp
85 90 95
He Asp Gin Asp Leu Asn Gin Lys Asn Pro Lys Gly A.la Ala Glu Phe
100 105 110
Ala Trp Asn He Met Asp Phe Lys Glu Asp Gin Asp Val Arg He Lys 115 120 125
Val Gly Tyr Glu Met Phe Asp Lys Val Pro Tyr Met Gin He Arg Glu
130 135 " 140
Asn Asn Trp Thr Leu Asn A.la Asn Met Lys Gly Lys Trp Asn Leu A.rg 145 150 155 160 Tyr Asp Leu
'Z) INFORMATION FOR SEQ IC MO: 437: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 154 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..154
(D) OTHER INFORMATION: / Ceres Seq. ID 2035578 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 437: Met Lys He His Ala Lys Glu Lys Val Pro Val Asn Ser Lys Thr His 1 5 10 15
Leu Gin Leu His Gly Glu Leu Asp Thr Gly Thr Gly Ala Pro Ser Tyr
20 25 30
Phe Cys Ala Met He Arg His Phe Phe Pro Glu Ala Ser Thr Gly Leu 35 40 45 Gly Val Gly Leu His Tyr Asp Lys Arg Gin Lys Leu Arg Cys Leu Val 50 55 60
Arg Gly Lys Lys Glu Phe Pro Val Arg Ala A.sp Lys Arg Val Thr Phe 65 70 75" 80
Asn He Lys Gly Arg Cys Asp He Asp Gin A.sp Leu Asn Gin Lys Asn 85 90 95
Pro Lys Gly Ala Ala Glu Phe Ala Trp Asn He Met Asp Phe Lys Glu
100 105 110
Asp Gin Asp Val Arg He Lys Val Gly Tyr Glu Met Phe Asp Lys Val 115 120 125 Pro Tyr Met Gin He A.rg Glu Asn Asn Trp Thr Leu Asn Ala Asn Met 130 135 140
Lys Gly Lys Trp Asn Leu A.rg Tyr Asp Leu 145 150
(2) INFORMATION FOR SEQ ID NO: 438: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 750 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..750
(D) OTHER INFORMATION: / Ceres Seq. ID 2036457 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 438: atgacgactc agatcagcaa gaagagaaag tttgtagcgg acggtgtgtt ctacgctgaa 60 ttgaatgagg ttcttacaag agagctagca gaggatggtt actctggtgt tgaggttagg 120 gttactccta tgaggactga gattatcatc agagctacac gtactcagaa tgttctcggt 180 gagaagggga ggagaattag ggaattgact tcccttgttc agaagagatt caagtttcca 240 gttgacagtg ttgagcttta tgccgagaag gttaacaaca gaggtctctg tgccatcgct 300 caggctgagt ctttacgtta caagcttctt ggtggtctcg ctgttcgtag ggcttgctat 360 ggtgtgttga ggtttgttat ggagagtgga gctaagggat gcgaggttat cgtgagtgga 420 aagcttcgtg ctgccagagc caagtctatg aagttcaaag atggctacat ggtgtcatct 480 ggtcaaecaa ctaaggaata catagactct gcagtgagac atgttttgct tagacaaαqt 540 gtgttaggaa tcaaggtgaa ggttatgctt gattgggacc ctaagggcat atcaggacca 600 aagacaccat tgcctgatgt tgtgatcatt cattctccta aagaagaaga ggccatctat 660 gcacctgctc aggttgctgc cccggctgct ctcgtagcag atgcaccact cacagccgta 720 gattaccctg cgatgatccc agtcgcctaa (2) INFORMATION FOR SEQ ID NO: 439: (i. SEQUENCE CHARACTERISTICS:
(A; LENGTH: 249 amino acids
(3, TYPE: amino acid
( C ) STRANDEDNESS:
'C, TOPOLOGY: linear (ii; MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..249
(D) OTHER INFORMATION: / Ceres Seq. ID 2036458 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 439:
Met Thr Thr Gin He Ser Lys Lys Arg Lys Phe Val Ala Asp Gly Val
1 5 10 15
Phe Tyr Ala Glu Leu Asn Glu Val Leu Thr A.rg Glu Leu Ala Glu Asp
20 25 30
Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He
35 40 45
He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg
50 55 60
Arg He A.rg Glu Leu Thr Ser Leu Val Gin Lys A.rg Phe Lys Phe Pro
65 70 80
Val Asp Ser 1 Glu Leu Tyr Ala Glu YS al Asn Asn A.rg Gly Leu 85 90 95_ Cys Ala He A.la Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly
100 105 110
Leu Ala Val A.rg Arg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu
115 120 125
Ser Gly Ala Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala
130 135 140
Ala A.rg Ala Lys Ser Met Lys Phe Lys Asp Gly Tyr Met Val Ser Ser 145 150 155 " 160
Gly Gin Pro Thr Lys Glu Tyr He Asp Ser Ala Val Arg His Val Leu
165 170 175
Leu Arg Gin Gly Val Leu Gly He Lys Val Lys Val Met Leu Asp Trp
180 185 190
Asp Pro Lys Gly He Ser Gly Pro Lys Thr Pro Leu Pro Asp Val Val
195 200 205
He He His Ser Pro Lys Glu Glu Glu Ala He Tyr Ala Pro Ala Gin
210 215 220
Val Ala Ala Pro Ala A.la Leu Val Ala Asp Ala Pro Leu Thr Ala Val 225 230 235 240
Asp Tyr Pro Ala Met He Pro Val Ala
245 (2) INFORMATION FOR SEQ ID NO: 440: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 206 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..206
(D) OTHER INFORMATION: / Ceres Seq. ID 2036459 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 440:
Met Arg Thr Glu He He He Arg Ala Thr Arg Thr GIr. Asn Val Leu 1 5 10 15
Gly Glu Lys Gly Arg A.rg He Arg Glu Leu Thr Ser Leu Val Gin Lys 20 25 30 Arg Phe Lys Phe Pro Val Asp Ser Val Glu Leu Tyr Ala Glu Lys Val 35 40 45
Asn A.sn A.rg Gly Leu Cys Ala He A.la Gin Ala Glu Ser Leu A.rg Tyr
50 55 60
Lys Leu Leu Gly Gly Leu Ala Val Arg Arg Ala Cys Tyr Gly Val Leu 65 70 75 ~ ~ 80
Arg Phe Val Met Glu Ser Gly Ala Lys Gly Cys Glu Val He Val Ser
85 9 " 95
Gly Lys Leu Arg Ala Ala Arg Ala Lys Ser Met Lys Phe Lys Asp Gly 100 105 110 Tyr Met Val Ser Ser Gly Gin Pro Thr Lys Glu Tyr He Asp Ser Ala 115 120 12Ξ
Val Arg His Val Leu Leu Arg Gin Gly Val Leu Gly He Lys Val Lys
130 135 140
Val Met Leu Asp Trp Asp Pro Lys Gly He Ser Gly Pre Lys Thr Pro 145 150 155 160
Leu Pro Asp Val Val He He His Ser Pro Lys Glu Glu Glu Ala He
165 170 175
Tyr Ala Pro Ala Gin Val Ala Ala Pro Ala Ala Leu Val A.la Asp A.la 180 185 190 Pro Leu Thr Ala Val A.sp Tyr Pro Ala Met He Pro Val Ala 195 200 205
(2) INFORMATION FOR SEQ ID NO : 441 : (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 549 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A.) NAME/KEY: -
(B) LOCATION: 1..549
(D) OTHER INFORMATION: / Ceres Seq. ID 2136585 (xi) SEQUENCE DESCRIPTION: SEQ ID NO : 441 : atggttctca agacggagct ttgtcgtttc agtggacaga agatttaccc aggaagagga 60 attaggttta tccgatctga ttctcaggtt ttcttgtttc ttaactcaaa atgtaagagg 120 tacttccata acaagttgaa gccatccaag cttgcatgga ctgccatgta cagaaagcaa 180 cacaagaagg atgcagcaca agaggctgtg aagagaagga gacgtgecac caagaagcca 240 tactcaaggt ecattgttgg tgctaccttg gaagtaattc agaagaagag agctgagaag 300 cctgaagttc gtgatgcagc cagggaagct gctctgcgtg agatcaagga aagaatcaaa 360 aagaccaaag atgaaaagaa ggctaagaag gtggaatttg cttctaagca acagaaggtc 420 aaggctaatt tccccaaagc tgctgctgca tccaagggtc ctaaggtggt ggtggcaaac 480 gctgaagagc ttaaagccat cttttctcac tctgcgtctt ttctgctagt agctactttt 540 agtagttga (2) INFORMATION FOR SEQ ID NO: 442: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 182 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..182
(D) OTHER INFORMATION: / Ceres Seq. IC 2036586 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 442: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 " " 15
Pro Gly Arg Gly He Arg Phe He Arg Ser A.sp Ser Gin Val Phe Leu
20 25 30
Phe Leu A.sn Ser Lys Cys Lys Arg Tyr Phe His Asn Lys Leu Lys Pro 35 40 45 Ser Lys Leu Ala Trp Thr Ala Met Tyr A.rg Lys Gin His Lys Lys Asp 50 55 60
Ala Ala Gin Glu Ala Val Lys Arg A.rg Arg A.rg Ala Thr Lys Lys Pro 65 70 75 " 80
Tyr Ser Arg Ser He Val Gly Ala Thr Leu Glu Val He Gin Lys Lys 85 90 95
Arg Ala Glu Lys Pro Glu Val Arg Asp Ala A a A.rg Glu A.la Ala Leu
100 105 110
Arg Glu He Lys Glu A.rg He Lys Lys Thr Lys A.sp Glu Lys Lys Ala 115 120 125 Lys Lys Val Glu Phe Ala Ser Lys Gin Gin Lys Val Lys Ala Asn Phe 130 135 140
Pro Lys Ala Ala Ala Ala Ser Lys Gly Pro Lys Val Val Val Ala A.sn 145 150 155 160
Ala Glu Glu Leu Lys Ala He Phe Ser His Ser Ala Ser Phe Leu Leu 165 170 175
Val Ala Thr Phe Ser Ser
180 (2) INFORMATION FOR SEQ ID NO: 443: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 127 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..127
(D) OTHER INFORMATION: / Ceres Seq. ID 2036587 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 443: Met Tyr Arg Lys Gin His Lys Lys Asp Ala A.la Gin Glu Ala Val Lys 1 " 5 10 15
A.rg A.rg A.rg Arg A.la Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly
20 25 30
Ala Thr Leu Glu Val He Gin Lys Lys Arg A.la Glu Lvs Pro Glu Val 35 40 45
Arg Asp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu A.rg He
50 55 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Val Glu Phe Ala Ser 65 " 70 75 80 Lys Gin Gin Lys Val Lys Ala Asn Phe Pro Lys Ala Ala Ala Ala Ser
85 90 95
Lys Gly Pro Lys Val Val Val Ala Asn Ala Glu Glu Leu Lys Ala He
100 105 110
Phe Ser His Ser Ala Ser Phe Leu Leu Val Ala Thr Phe Ser Ser 115 120 125
(2) INFORMATION FOR SEQ ID NO: 444: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 486 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: DNA (genomic)
(ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..486
(D) OTHER INFORMATION: / Ceres Seq. ID 203955 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 444: atggctgtcg tcggcgctcc aatatcgtct ccggcggctc agctgcagac acaatttctc 60 tccaatccca ttctcccccg ctttcgccgg tctttctcca ccggaaaatc accagcaact 120 ttctccgtcg tagctatggc tccccagaaa aaggtgaaca aatatgatgc caagtggaag 180 aaacaatggt acggagctgg attgtttttc gaagggagtg agcaaataaa cgttgatgtt 240 ttcaagaagc tggagaagcg aaaagtgttg agcaacgttg agaaatctgg cctgctgtca 300 aaagcagagg ggttgggact cacattgtca tctcttgaga agcttaaagt cttctccaaa 360 gcagaggacc ttggtcttct cagtctcctt gagaacttag ctggaacatc gcctgcggtc 420 ttagcctcgg ctgcattacc agctctcacg agctgctatt gtagccgtgg tgttgatccc 480 ggatga (2) INFORMATION FOR SEQ ID NO: 445:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 161 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..161
(D) OTHER INFORMATION: / Ceres Seq. ID 2039555 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 445: Met Ala Val Val Gly Ala Pro He Ser Ser Pro Ala Ala Gin Leu Gin 1 5 10 15
Thr Gin Phe Leu Ser Asn Pro He Leu Pro Arg Phe Arg Arg Ser Phe
20 25 30
Ser Thr Gly Lys Ser Pro Ala Thr Phe Ser Val Val Ala Met Ala Pro
35 40 45
Gin Lys Lys Val Asn Lys Tyr Asp Ala Lys Trp Lys Lys Gin Trp Tyr
50 55 60
Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu Gin He Asn Val Asp Val 65 70 75 80
Phe Lys Lys Leu Glu Lys Arg Lys Val Leu Ser Asn Val Glu Lys Ser
85 90 95
Gly Leu Leu Ser Lys Ala Glu Gly Leu Gly Leu Thr Leu Ser Ser Leu
100 105 110
Glu Lys Leu Lys Val Phe Ser Lys Ala Glu Asp Leu Gly Leu Leu Ser
115 120 125
Leu Leu Glu Asn Leu Ala Gly Thr Ser Pro Ala Val Leu Ala Ser Ala
130 135 140
Ala Leu Pro Ala Leu Thr Ser Cys Tyr Cys Ser Arg Gly Val Asp Pro 145 150 155 160
Gly
(2) INFORMATION FOR SEQ ID NO: 446: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 116 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..116
(D) OTHER INFORMATION: / Ceres Seq. ID 2039556 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 446: Met Ala Pro Gin Lys Lys Val Asn Lys Tyr Asp Ala Lys Trp Lys Lys 1 5 10 . * 15
Gin Trp Tyr Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu Gin He Asn
20 25 30
Val Asp Val Phe Lys Lys Leu Glu Lys Arg Lys Val Leu Ser Asn Val 35 40 45
GGlluu LLyyss Ser Gly Leu Leu Ser Lys Ala Glu Gly Leu Gly Leu Thr Leu
50 55 60
Ser Ser Leu Glu Lys Leu Lys Val Phe Ser Lys Ala Glu Asp Leu Gly
65 70 75 8θ"
Leu Leu Ser Leu Leu Glu Asn Leu Ala Gly Thr Ser Pro Ala Val Leu 85 90 95
Ala Ser A.la A.la Leu Pro Ala Leu Thr Ser Cys Tyr Cys Ser A.rq Gly
100 105 110
Val Asp Pro Gly 115 (2) INFORMATION FOR SEQ ID NO: 447: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 378 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..378 (D) OTHER INFORMATION: / Ceres Seq. ID 2044283
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 447: atggcgaatt tgatgatgag attaccaatt agcttgagaa gcttctctgt ttcagcttct 60 tcatccaacg gttcgccgcc ggtgatcgga ggatctagcg gcggtgtagg accgatgatt 120 gtggaattac cgttggagaa gatacgaaga ccgttgatgc gaaccagatc caacgatcag 180 aacaaagtga aagagcttat ggatagtatc cgtcaaatcg gtcttcaagt tccgattgat 240 gtgattgaag ttgatggaac ttactatggg ttctcgggat gtcacagata cgaggcgcat 300 cagaagctag ggcttccaac tatacgttgc aaaatccgta aaggaacaaa ggaaacatta 360 aggcatcatc ttcgctga (2) INFORMATION FOR SEQ ID NO: 448: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 125 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..125
(D) OTHER INFORMATION: / Ceres Seq. ID 2044284 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 448:
Met Ala Asn Leu Met Met Arg Leu Pro He Ser Leu Arg Ser Phe Ser 1 5 10 15
Val Ser Ala Ser Ser Ser Asn Gly Ser Pro Pro Val He Gly Gly Ser 20 25 30 Ser Gly Gly Val Gly Pro Met He Val Glu Leu Pro Leu Glu Lys He 35 40 45
Arg Arg Pro Leu Met Arg Thr Arg Ser Asn Asp Gin Asn Lys Val Lys
50 55 60
Glu Leu Met Asp Ser He Arg Gin He Gly Leu Gin Val Pro He Asp 65 70 75 80
Val He Glu Val Asp Gly Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg 85 90 95 Tyr Glu Ala His Gin Lys Leu Gly Leu Pro Thr He Arg Cys Lys He
100 105 110
Arg Lys Gly Thr Lys Glu Thr Leu A.rg His His Leu Arg 115 120 125 (2) INFORMATION FOR SEQ ID NO: 449: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 121 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..121 (D) OTHER INFORMATION: / Ceres Seq. ID 2044285
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 449: Met Met .Arg Leu Pro He Ser Leu Arg Ser Phe Ser Val Ser Ala Ser 1 5 10 15
Ser Ser Asn Gly Ser Pro Pro Val He Gly Gly Ser Ser Gly Gly Val 20 25 30
Gly Pro Met He Val Glu Leu Pro Leu Glu Lys He Arg Arg Pro Leu
35 40 45
Met A.rg Thr Arg Ser A.sn Asp Gin Asn Lys Val Lys Glu Leu Met Asp 50 55 60 Ser He Arg Gin He Gly Leu Gin Val Pro He Asp Val He Glu Val 65 70 75 80
Asp Gly Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg Tyr Glu Ala His
85 90 95
Gin Lys Leu Gly Leu Pro Thr He Arg Cys Lys He Arg Lys Gly Thr 100 105 110
Lys Glu Thr Leu Arg His His Leu Arg
115 120
(2) INFORMATION FOR SEQ ID NO: 450: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 120 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..120
(D) OTHER INFORMATION: / Ceres Seq. ID 2044286 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 450: Met Arg Leu Pro He Ser Leu Arg Ser Phe Ser Val Ser Ala Ser Ser 1 5 10 15
Ser A.sn Gly Ser Pro Pro Val He Gly Gly Ser Ser Gly Gly Val Gly
20 25 30
Pro Met He Val Glu Leu Pro Leu Glu Lys He Arg Arg Pro Leu Met 35 40 45
Arg Thr Arg Ser Asn Asp Gin Asn Lys Val Lys Glu Leu Met Asp Ser
50 55 60
He Arg Gin He Gly Leu Gin Val Pro He Asp Val He Glu Val Asp 65 70 75 80 Gly Thr Tyr Tyr Gly Phe Ser Gly Cys His Arg Tyr Glu Ala His Gin
85 90 95
Lys Leu Gly Leu Pro Thr He Arg Cys Lys He Arg Lys Gly Thr Lys
100 105 110
Glu Thr Leu Arg His His Leu Arg 115 120
(2) INFORMATION FOR SEQ ID NO: 451: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1236 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1236
(D) OTHER INFORMATION: / Ceres Seq. ID 2048114 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 451: atgagaagac ctagtcaaat gatgaggctt ctattaacat cctttttcgg tgttattgtt 60 ggtttcctta tgggtattac ttttccaacc ttgactttaa ctaagatgaa tcttccatcc 120 acattgtttc cctcgattga tcttgcatac attgaggata aatactctga catatcaaga 180 caaagactat ttggttcttg gtcttcgaca aaaggcctca aactcaagaa tgacatccct 240 gaccctccat ataactataa tgacactaag gttgatgata gaacgttega gctattgcag 300 atatgggttt cgactaaccc ccgtggtgct gagaggctac caccagatat agtcacgcct 360 gaatcagatt tttacctccg tcgactgtgg ggcgacccta atgaggattt aacagtcaag 420 cagcggtatc tagtaacatt tacggttggc tatgatcaga ggaaaaatat agacactgtg 480 ttgaagaagt tctcagataa cttctctata atgctgtttc actacgatgg ccgggcaaqc 540 qaatgggaag agtttgaatg gtccaagcga gccattcatg tgagcattcg gaaacaaaca 600 aaatggtggt acgctaagcg atttcttcat cctgacatag ttgcccccta tgaatatatc 660 ttcatatggg atgaggatct tggcgtggaa cactttgatt cggaaaaata tctggcggtg ^20 gtgaagaagc atggtttgga aatctcacag cctggattag agccatatga agggctcaca "80 tgggagatga ccaagaaaag agacgacact gaagtccaca agcatgctga ggaaaggaat 840 gggtggtgca ctgatcccaa tttaccccct tgtgcagcgt ttgtggagat tatggctcct 900 gttttctccc gcaaggcatg gcgctgtgtg tggcatatga ttcagaacga tttgattcat 960 ggatggggtc tggactttgc cgttcggaaa tgtgttcaga acgcacacga gaaaattgga 1020 gttgtagatg ctcaatggat tatacatcaa ggtgttccat cattagggaa tcaaggacaa 1080 ccagagcaag ggaaacaacc atgggaaggg gtgagagaac gatgcaggag agagtggaca 1140 atgtttcaag acagattgga tgatgctgaa aaagcttatt ttgaagcatc tgctcacaag 1200 aatgcttctt cacggcctca cgggaattgg gtatag (2) INFORMATION FOR SEQ ID NO: 452: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 411 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..411
(D) OTHER INFORMATION: / Ceres Seq. ID 2048115 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 452: Met Arg Arg Pro Ser Gin Met Met Arg Leu Leu Leu Thr Ser Phe Phe 1 5 10 15
Gly Val He Val Gly Phe Leu Met Gly He Thr Phe Pro Thr Leu Thr
20 25 30
Leu Thr Lys Met Asn Leu Pro Ser Thr Leu Phe Pro Ser He Asp Leu 35 40 45 Ala Tyr He Glu Asp Lys Tyr Ser Asp He Ser Arg Gin Arg Leu Phe 50 55 60
Gly Ser Trp Ser Ser Thr Lys Gly Leu Lys Leu Lys A.sn Asp He Pro 65 70 75 80
Asp Pro Pro Tyr Asn Tyr Asn Asp Thr Lys Val Asp Asp Arg Thr Phe 85 90 95
Glu Leu Leu Gin He Trp Val Ser Thr Asn Pro Arg Gly Ala Glu Arg
100 105 110
Leu Pro Pro Asp He Val Thr Pro Glu Ser Asp Phe Tyr Leu Arg Arq 115 120 125 Leu Trp Gly Asp Pro Asn Glu Asp Leu Thr Val Lys Gin Arg Tyr Leu 130 135 140
Val Thr Phe Thr Val Gly Tyr Asp Gin Arg Lys Asn He Asp Thr Val 145 150 155 160
Leu Lys Lys Phe Ser Asp Asn Phe Ser He Met Leu Phe His Tyr Asp
165 170 175
Gly Arg Ala Ser Glu Trp Glu Glu Phe Glu Trp Ser Lys Arg Ala He 180 185 190
His Val Ser He Arg Lys Gin Thr Lys Trp Trp Tyr Ala Lys Arg Phe
195 200 " 205
Leu His Pro Asp He Val A.la Pro Tyr Glu Tyr He Phe He Trp Asp
210 215 220 Glu Asp Leu Gly Val Glu His Phe Asp Ser Glu Lys Tyr Leu Ala Val
225 230 235 240
Val Lys Lys His Gly Leu Glu He Ser Gin Pro Gly Leu Glu Pro Tyr
245 250 " 255
Glu Gly Leu Thr Trp Glu Met Thr Lys Lys Arg A.sp Asp Thr Glu Val 260 265 270
His Lys His Ala Glu Glu Arg Asn Gly Trp Cys Thr Asp Pro Asn Leu
275 280 285
Pro Pro Cys Ala Ala Phe Val Glu He Met Ala Pro Val Phe Ser Arg
290 295 300 Lys Ala Trp Arg Cys Val Trp His Met He Gin Asn Asp Leu He His
305 310 315 320
Gly Trp Gly Leu Asp Phe Ala Val Arg Lys Cys Val Gin Asn A.la His
325 330 335
Glu Lys He Gly Val Val Asp Ala Gin Trp He He His Gin Gly Val 340 345 350
Pro Ser Leu Gly Asn Gin Gly Gin Pro Glu Gin Gly Lys Gin Pro Trp
355 360 ' 365
Glu Gly Val Arg Glu Arg Cys Arg Arg Glu Trp Thr Met Phe Gin Asp 370 375 380 Arg Leu Asp Asp Ala Glu Lys Ala Tyr Phe Glu Ala Ser Ala His Lys 385 390 395 400
Asn Ala Ser Ser Arg Pro His Gly Asn Trp Val
405 410
(2) INFORMATION FOR SEQ ID NO: 453: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 405 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..405
(D) OTHER INFORMATION: / Ceres Seq. ID 2048116 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 453:
Met Met Arg Leu Leu Leu Thr Ser Phe Phe Gly Val He Val Gly Phe 1 5 10 15
Leu Met Gly He Thr Phe Pro Thr Leu Thr Leu Thr Lys Met Asn Leu 20 25 30 Pro Ser Thr Leu Phe Pro Ser He Asp Leu Ala Tyr He Glu Asp Lys 35 40 45
Tyr Ser Asp He Ser Arg Gin Arg Leu Phe Gly Ser Trp Ser Ser Thr
50 55 60
Lys Gly Leu Lys Leu Lys Asn Asp He Pro Asp Pro Pro Tyr Asn Tyr 65 70 75 80
Asn Asp Thr Lys Val Asp Asp Arg Thr Phe Glu Leu Leu Gin He Trp
85 90 95
Val Ser Thr Asn Pro Arg Gly Ala Glu Arg Leu Pro Pro Asp He Val 100 105 110 Thr Pro Glu Ser Asp Phe Tyr Leu Arg Arg Leu Trp Gly Asp Pro Asn 115 120 125
Glu Asp Leu Thr Val Lys Gin Arg Tyr Leu Val Thr Phe Thr Val Gly 130 135 140
Tyr Asp Gin Arg Lys Asn He Asp Thr Val Leu Lys Lys Phe Ser Asp 145 150 155 160
Asn Phe Ser He Met Leu Phe His Tyr Asp Gly Arg Ala Ser Glu Trp 165 170 175
Glu Glu Phe Glu Trp Ser Lys Arg Ala He His Val Ser He Arg Lys
180 185 190
Gin Thr Lys Trp Trp Tyr Ala Lys Arg Phe Leu His Pro Asp He Val 195 200 205 Ala Pro Tyr Glu Tyr He Phe He Trp Asp Glu Asp Leu Gly Val Glu 210 215 220
His Phe Asp Ser Glu Lys Tyr Leu Ala Val Val Lys Lys His Gly Leu 225 230 235 240
Glu He Ser Gin Pro Gly Leu Glu Pro Tyr Glu Gly Leu Thr Trp Glu 245 250 255
Met Thr Lys Lys Arg Asp A.sp Thr Glu Val His Lys His Ala Glu Glu
260 " 265 270
Arg A.sn Gly Trp Cys Thr Asp Pro A.sn Leu Pro Pro Cys Ala Ala Phe 275 280 285 Val Glu He Met Ala Pro Val Phe Ser Arg Lys Ala Trp Arg Cys Val 290 295 300
Trp His Met He Gin Asn Asp Leu He His Gly Trp Gly Leu Asp Phe 305 310 315 " * 320
Ala Val Arg Lys Cys Val Gin Asn Ala His Glu Lys He Gly Val Val 325 330 335
Asp Ala Gin Trp He He His Gin Gly Val Pro Ser Leu Gly Asn Gin
340 345 350
Gly Gin Pro Glu Gin Gly Lys Gin Pro Trp Glu Gly Val Arg Glu Arg 355 360 365 Cys Arg Arg Glu Trp Thr Met Phe Gin Asp Arg Leu Asp Asp Ala Glu 370 375 380
Lys Ala Tyr Phe Glu Ala Ser Ala His Lys Asn Ala Ser Ser Arg Pro 385 390 395 400
His Gly Asn Trp Val 405
(2) INFORMATION FOR SEQ ID NO: 454: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 404 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..404
(D) OTHER INFORMATION: / Ceres Seq. ID 2048117 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 454: Met Arg Leu Leu Leu Thr Ser Phe Phe Gly Val He Val Gly Phe Leu 1 5 10 15 Met Gly He Thr Phe Pro Thr Leu Thr Leu Thr Lys Met Asn Leu Pro
20 25 30
Ser Thr Leu Phe Pro Ser He Asp Leu Ala Tyr He Glu Asp Lys Tyr
35 40 45
Ser Asp He Ser Arg Gin Arg Leu Phe Gly Ser Trp Ser Ser Thr Lys 50 55 60
Gly Leu Lys Leu Lys Asn Asp He Pro Asp Pro Pro Tyr Asn Tyr Asn 65 70 75 80
Asp Thr Lys Val Asp Asp Arg Thr Phe Glu Leu Leu Gin He Trp Val 85 90 95 Ser Thr Asn Pro Arg Gly Ala Glu Arg Leu Pro Pro Asp He Val Thr
100 105 110
Pro Glu Ser Asp Phe Tyr Leu Arg Arg Leu Trp Gly Asp Pro Asn Glu 115 120 125
Asp Leu Thr Val Lys Gin Arg Tyr Leu Val Thr Phe Thr Val Gly Tyr
130 135 140
Asp Gin Arg Lys Asn He Asp Thr Val Leu Lys Lys Phe Ser Asp Asn 145 150 155 160
Phe Ser He Met Leu Phe His Tyr Asp Gly Arg A.la Ser Glu Trp Glu
165 170 175
Glu Phe Glu Trp Ser Lys Arg Ala He His Val Ser He Arg Lys Gin 180 185 190 Thr Lys Trp Trp Tyr Ala Lys Arg Phe Leu His Pro Asp He Val Ala 195 200 205
Pro Tyr Glu Tyr He Phe He Trp Asp Glu Asp Leu Gly Val Glu His
210 215 220
Phe Asp Ser Glu Lys Tyr Leu Ala Val Val Lys Lys His Gly Leu Glu 225 230 235 240
He Ser Gin Pro Gly Leu Glu Pro Tyr Glu Gly Leu Thr Trp Glu Met
245 * 250 255
Thr Lys Lys Arg Asp A.sp Thr Glu Val His Lys His Ala Glu Glu Arg 260 265 270 Asn Gly Trp Cys Thr Asp Pro Asn Leu Pro Pro Cys Ala Ala Phe Val 275 280 285
Glu He Met Ala Pro Val Phe Ser Arg Lys Ala Trp Arg Cys Val Trp
290 295 300
His Met He Gin Asn Asp Leu He His Gly Trp Gly Leu Asp Phe Ala 305 310 315 320
Val Arg Lys Cys Val Gin Asn Ala His Glu Lys He Gly Val Val Asp
325 330 " 335
Ala Gin Trp He He His Gin Gly Val Pro Ser Leu Gly Asn Gin Gly 340 345 350 Gin Pro Glu Gin Gly Lys Gin Pro Trp Glu Gly Val Arg Glu Arg Cys 355 360 365
Arg Arg Glu Trp Thr Met Phe Gin Asp Arg Leu Asp Asp Ala Glu Lys
370 375 380
Ala Tyr Phe Glu Ala Ser Ala His Lys Asn Ala Ser Ser Arg Pro His 385 390 395 " 400
Gly Asn Trp Val
(2' INFORMATION FOR SEQ ID NO: 455: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 649 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..649
(D) OTHER INFORMATION: / Ceres Seq. ID 2048271 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 455: ggaatttctc actctctcta tctctcttag ccagctctga tcatttcgat ttttttccgg 60 tgaaaaggga ggagaaacat ggttgtacgt atcagactgt cgagatttgg atgcaaaaat 120 cggccatttt ttagggttat ggctgctgat agcagatctc caagagacgg gaagcatctt 180 gaggtcttag gttacttcaa tcctttgcca ggccaggacg gtggtaagag gatgggtcte 240 aagttcgatc gaattaagta ctggttatct gttggtgctc agccatcaga cccggttcaa 300 cgtctcctat tcagatccgg tttacttcct cctcctccaa tggtggctat gggacgtaaa 360 ggtggagcac gagacacacg cccagttgat ccgatgactg gtcgctatgt ggatgcagag 420 aataaaacag ttaatgccaa tgataaccag cctaaggaag aggatacaga agccaagagt 480 gcatgattca ttagccttct gtcatcgtag cttttcaagt tcactttgtt gtcgattata 540 ttgtgtaatg cagcattaga caactgactt gtttcctttg tttggcgata aacggcaagg 600 tgtttggcac tttttgcaga aacggcacat attttgcatt gggatattt (2) INFORMATION FOR SEQ ID NO: 456: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 135 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..135
(D) OTHER INFORMATION: / Ceres Seq. ID 2048272 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 456:
Met Val Val Arg He Arg Leu Ser Arg Phe Gly Cys Lys Asn Arg Pro 1 5 10 15
Phe Phe Arg Val Met Ala Ala A.sp Ser Arg Ser Pro Arg Asp Gly Lys 20 25 30 His Leu Glu Val Leu Gly Tyr Phe Asn Pro Leu Pro Gly Gin Asp Gly 35 40 45
Gly Lys Arg Met Gly Leu Lys Phe Asp A.rg He Lys Tyr Trp Leu Ser
50 55 60
Val Gly Ala Gin Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser 65 70 l ' " 80
Gly Leu Leu Pro Pro Pro Pro Met Val A.la Met Gly Arg Lys Gly Gly
85 90 95
A.la Arg Asp Thr Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp 100 105 110 Ala Glu Asn Lys Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu 115 120 125
Asp Thr Glu Ala Lys Ser Ala 130 135
(2) INFORMATION FOR SEQ ID NO: 457: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: / Ceres Seq. ID 2048273 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 457:
Met A.la Ala Asp Ser Arg Ser Pro Arg Asp Gly Lys His Leu Glu Val 1 5 10 15
Leu Gly Tyr Phe Asn Pro Leu Pro Gly Gin Asp Gly Gly Lys Arg Met 20 25 30 Gly Leu Lys Phe Asp Arg He Lys Tyr Trp Leu Ser Val Gly Ala Gin 35 40 45
Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser Gly Leu Leu Pro
50 55 60
Pro Pro Pro Met Val Ala Met Gly Arg Lys Gly Gly Ala Arg Asp Thr 65 70 75" ' 80
Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp Ala Glu Asn Lys
85 90 95
Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu Asp Thr Glu Ala 100 105 110 Lys Ser Ala 115 (2) INFORMATION FOR SEQ ID NO: 458: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 84 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..84
(D) OTHER INFORMATION: / Ceres Seq. ID 2048274 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 458: Met Gly Leu Lys Phe Asp Arg He Lys Tyr Trp Leu Ser Val Gly Ala 1 5 10 15
Gin Pro Ser Asp Pro Val Gin Arg Leu Leu Phe Arg Ser Gly Leu Leu
20 25 30~
Pro Pro Pro Pro Met Val Ala Met Gly Arg Lys Gly Gly Ala Arg Asp
35 40 45
Thr Arg Pro Val Asp Pro Met Thr Gly Arg Tyr Val Asp Ala Glu Asn
50 55 60
Lys Thr Val Asn Ala Asn Asp Asn Gin Pro Lys Glu Glu Asp Thr Glu 65 70 75 80
A.la Lys Ser Ala
(2) INFORMATION FOR SEQ ID NO: 459: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 285 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..285 (D) OTHER INFORMATION: / Ceres Seq. ID 2048331
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 459: atgaaactgt gtaatcacca tactggaaag tttgtttcgg agagcgtcga agatcagact 60 gagcaggtac tcaaaaacat gggggagata ttgaaagcta gtggtgctga ttattcctcg 120 gtggtgaaga caacaatcat gttggctgat ttggctgact tcaagacagt gaacgagata 180 tatgccaaat acttcccagc tccttctcca gcacgatcga cgtatcaagt tgcagctttg 240 cctctaaacg ccaagatcga gattgaatgt attgcaacac tctag (2) INFORMATION FOR SEQ ID NO: 460: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 94 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..94
(D) OTHER INFORMATION: / Ceres Seq. ID 2048332 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 460: Met Lys Leu Cys Asn His His Thr Gly Lys Phe Val Ser Glu Ser Val 1 5 10 15
Glu Asp Gin Thr Glu Gin Val Leu Lys Asn Met Gly Glu He Leu Lys
20 25 30
Ala Ser Gly Ala Asp Tyr Ser Ser Val Val Lys Thr Thr He Met Leu
35 40 45
Ala Asp Leu Ala Asp Phe Lys Thr Val Asn Glu He Tyr Ala Lys Tyr
50 55 60
Phe Pro Ala Pro Ser Pro Ala Arg Ser Thr Tyr Gin Val Ala Ala Leu
65 70 75 50
Pro Leu Asn Ala Lys He Glu He Glu Cys He Ala Thr Leu
90
(2) INFORMATION FOR SEQ ID NO: 461: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 68 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..68
(D) OTHER INFORMATION: / Ceres Seq. ID 2048333 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 461:
Met Gly Glu He Leu Lys Ala Ser Gly Ala Asp Tyr Ser Ser Val Val 1 10 15
Lys Thr Thr He Met Leu Ala Asp Leu Ala Asp Phe Lys Thr Val A.sn
20 25 30 Glu He Tyr Ala Lys Tyr Phe Pro Ala Pro Ser Pro Ala Arg Ser Thr 35 40 45
Tyr Gin Val Ala A.la Leu Pro Leu Asn Ala Lys He Glu He Glu Cys
50 55 60
He Ala Thr Leu 65
(2) INFORMATION FOR SEQ ID NO: 462:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 48 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..48 (D) OTHER INFORMATION: / Ceres Seq. ID 2048334 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 462:
Met Leu Ala Asp Leu Ala Asp Phe Lys Thr Val Asn Glu He Tyr Ala 1 5 10 15
Lys Tyr Phe Pro Ala Pro Ser Pro Ala Arg Ser Thr Tyr Gin Val Ala
20 25 30
Ala Leu Pro Leu Asn Ala Lys He Glu He Glu Cys He Ala Thr Leu
35 40 45
(2) INFORMATION FOR SEQ ID NO: 463: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 627 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..627
(D) OTHER INFORMATION: / Ceres Seq. ID 2048466 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 463: atgatggaca agaatgaaaa ccctagtttt ttgctctctc gaagttccgt gcgactctct 60 gctcgagcaa gatctcctac cgatacaatg attatctcag aggctaaccg caaagaaatc 120 tgcaagtacc tcttcaaaga aggagtttgc tttgcgaaga aggatttcaa tcttgctaag 180 catccgttga tcgatgtccc caacctacaa gtgattaagc ttatgcagag tttcaaatcc 240 aaggagtatg ttagggagac atttgcctgg atgcattact attggttttt gaccaatgaa 300 gggatcgagt tcttgagaac ttatcttaat cttccatctg atgttgttcc tgctactttg 360 aagaagtcag ctaagcctgg tggtcgtcca tttggtggcc cacctggtga tcgctcaaga 420 ggacctcgcc atgaaggagg agaccgtccc aggtttggtg accgtgatgg gtaccgtgca 480 ggtcctcgag ctggtggtga gtttggaggt gaaaagggtg gagctcccgc agattaccag 540 ccatctttcc aaggaagtgg ccgtggtttt ggccgtggtg ctggtggcta cagcgcagct 600 gcaccatctg gttcaggttt gccttga (2) INFORMATION FOR SEQ ID NO: 464: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 208 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..208
(D) OTHER INFORMATION: ' Ceres Seq. ID 2048467 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 464:
Met Met Asp Lys Asn Glu Asn Pro Ser Phe Leu Leu Ser Arg Ser Ser 1 5 10 15
Val Arg Leu Ser A.la Arg Ala Arg Ser Pro Thr Asp Thr Met He He 20 25 30 Ser Glu Ala Asn Arg Lys Glu He Cys Lys Tyr Leu Phe Lys Glu Gly 35 40 45
Val Cys Phe Ala Lys Lys Asp Phe A.sn Leu Ala Lys His Pro Leu He
50 55 60
Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser Phe Lys Ser 65 70 ' 75 80
Lvs Glu Tyr Val Arg Glu Thr Phe A.la Trp Met His Tyr Tyr Trp Phe
85 90 95
Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro 100 105 110 Ser Asp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly 115 120 125
Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg Ser Arg Gly Pro Arg His
130 135 140
Glu Gly Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arq Ala 145 150 155 160
Gly Pro Arg Ala Gly Gly Glu Phe Gly Gly Glu Lys Gly Gly Ala Pro
165 170 175
Ala Asp Tyr Gin Pro Ser Phe Gin Gly Ser Gly Arg Gly Phe Gly Arg 180 185 190 Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser Gly Leu Pro 195 200 205
< 2 ) INFORMATION FOR SEQ ID NO: 465: (i^ SEQUENCE CHARACTERISTICS:
(A) LENGTH: 207 ammo acids (B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..207
(D) OTHER INFORMATION: / Ceres Seq. ID 2048468 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 465: Met Asp Lys Asn Glu Asn Pro Ser Phe Leu Leu Ser Arq Ser Ser Val 1 5 10 15
Arg Leu Ser Ala Arg Ala Arg Ser Pro Thr Asp Thr Met He He Ser
20 25 30
Glu Ala A.sn Arg Lys Glu He Cys Lys Tyr Leu Phe Lys Glu Gly Val 35 40 45 Cys Phe Ala Lys Lys Asp Phe Asn Leu Ala Lys His Pro Leu He Asp 50 55 60
Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser Phe Lys Ser Lys 65 70 75 80
Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His Tyr Tyr Trp Phe Leu 85 90 95
Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro Ser 100 105 110 A.sp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly Arg
115 120 125
Pro Phe Gly Gly Pro Pro Gly Asp Arg Ser Arg Gly Pro Arg His Glu
130 135 140 Gly Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg Ala Gly
145 150 155 160
Pro Arg Ala Gly Gly Glu Phe Gly Gly Glu Lys Gly Gly Ala Pro Ala
165 170 175
Asp Tyr Gin Pro Ser Phe Gin Gly Ser Gly Arg Gly Phe Gly Arg Gly 180 185 190
Ala Gly Gly Tyr Ser A.la Ala A.la Pro Ser Gly Ser Gly Leu Pro
195 200 205
(2) INFORMATION FOR SEQ ID NO: 466: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 179 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..179
(D) OTHER INFORMATION: / Ceres Seq. ID 2048469 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 466: Met He He Ser Glu Ala A.sn Arg Lys Glu He Cys Lys Tyr Leu Phe 1 5 10 15
Lys Glu Gly Val Cys Phe A.la Lys Lys A.sp Phe A.sn Leu A.la Lys His
20 25 30
Pro Leu He Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser 35 40 45
Phe a Trp Met His Tyr
Tyr Trp Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu 65 70 75 80 A.sn Leu Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys
85 90 95
Pro Gly Gly A.rg Pro Phe Gly Gly Pro Pro Gly Asp Arg Ser Arg Gly
100 105 110
Pro Arg His Glu Gly Gly Asp A.rg Pro Arg Phe Gly Asp Arg Asp Gly " 115 120 125
Tyr Arg Ala Gly Pro Arg Ala Gly Gly Glu Phe Gly Gly Glu Lys Gly
130 135 140
Gly Ala Pro Ala Asp Tyr Gin Pro Ser Phe Gin Gly Ser Gly Arg Gly 145 150 155 160 Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser
165 170 175
Gly Leu Pro
(2) INFORMATION FOR SEQ ID NO: 467: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 585 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..585
(D) OTHER INFORMATION: / Ceres Seq. ID 2050485 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 467: atcttcggaa agtctcattt ctcgatcccc aattcgtgga ttagggttaa aagaaccatt 60 tttattctcg tcgcgcaaca acaaatccag atcgaaaaag gaagaagaga tcgaaatggc 120 gttgagaagg gtttacagtg aaatcagagg gaagaaggtg acggagcttc caggctatat 180 caaatcgact ttttcaatgg agaccgtgaa gacctctgtg aagagaggac tcgataacta 240 caacgaaaaa tacattcaga ccagctccgt tgatcctatc cttcatatct gcttctacgg 300 catggctttc tcttaccttg tcgctctccc taatgagcgt cgccatcttg agcatcagca 360 gcatgctaag gagcacggtg gtcattgatc tcgtgggaat cgtttcgatc tcgagatgat 420 tttagggggg ttgctgtgaa atctttctct gcttgatggt gacgacgact caagaattgt 480 gtcttattgt ttcgttttct tgaattttcc tggataatgt tgacctaaag gaaaaccttt 540 ctttcgaatt acactccatg atagtcaata attgaagcat catga (2) INFORMATION FOR SEQ ID NO: 468: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 128 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..128
(D) OTHER INFORMATION: / Ceres Seq. ID 2050486 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:468~:
Ser Ser Glu Ser Leu He Ser Arg Ser Pro He Arg Gly Leu Gly Leu 1 5 10 15'
Lys Glu Pro Phe Leu Phe Ser Ser Arg A.sn A.sn Lys Ser Arg Ser Lys 20 25 30 Lys Glu Glu Glu He Glu Met Ala Leu Arg Arg Val Tyr Ser Glu He 35 40 45
Arg Gly Lys Lys Val Thr Glu Leu Pro Gly Tyr He Lys Ser Thr Phe
50 55 60
Ser Met Glu Thr Val Lys Thr Ser Val Lys Arg Gly Leu Asp Asn Tyr 65 70 75 80
Asn Glu Lys Tyr He Gin Thr Ser Ser Val Asp Pro He Leu His He
85 90 95
Cys Phe Tyr Gly Met Ala Phe Ser Tyr Leu Val Ala Leu Pro Asn Glu 100 105 110 Arg Arg His Leu Glu His Gin Gin His Ala Lys Glu His Gly Gly His 115 120 125
(2) INFORMATION FOR SEQ ID NO: 469: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 90 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..90
(D) OTHER INFORMATION: / Ceres Seq. ID 2050487 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 469: Met Ala Leu Arg Arg Val Tyr Ser Glu He Arg Gly Lys Lys Val Thr 1 5 10 15
Glu Leu Pro Gly Tyr He Lys Ser Thr Phe Ser Met Glu Thr Val Lys
20 25 30
Thr Ser Val Lys Arg Gly Leu Asp Asn Tyr Asn Glu Lys Tyr He Gin 35 40 45 Thr Ser Ser Val Asp Pro He Leu His He Cys Phe Tyr Gly Met Ala 50 55 60
Phe Ser Tyr Leu Val Ala Leu Pro Asn Glu Arg Arg His Leu Glu His 65 70 75 80
Gin Gin His Ala Lys Glu His Gly Gly His 85 90
(2) INFORMATION FOR SEQ ID NO: 470: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 516 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION:- 1..516
(D) OTHER INFORMATION: / Ceres Seq. ID 2050708 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 470: caaccaaaac aaaacataaa aaacaagtgg aagctttaaa acgagaggga gagagcaaaa 60 atggcgacgt cgggaacgta cgtgacggaa gttccgctaa aaggatcggc cgagaaatae 120 tacaagaggt ggaagaacga gaaccatgtc ttccctgatg ctatcggcca ecacatccaa 180 aatgttaccg ttcacgaagg cgaacatgac tctcacgggt ctatcaggag ttggaactac 240 acatσggatg gaaaggagga ggtgttcaag gagagaagag agatagacga tgagaccaaa 300 acgttgacgt taagaggact tgagggtcac gtgatggagc agctcaaagt gtacgacgtc 360 gtctaccaat teattcceaa atctgaggat acctgcatcg gcaaaatcac tttaatatgg 420 qagaagcgca acgatgattc cccagaacca agcgggtaca tgaaattcgt caagagcttg 480 gttgctgaca tgggaaacca cgttagcaaa acttaa 2, INFORMATION FOR SEQ ID NO: 471: (ii SEQUENCE CHARACTERISTICS:
'A; LENGTH: 151 ammo acids . B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear iii) MOLECULE TYPE: peptiae (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..151 (D) OTHER INFORMATION: / Ceres Seq. ID 2050709
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 471: Met Ala Thr Ser Gly Thr Tyr Val Thr Glu Val Pro Leu Lys Gly Ser 1 5 10 15
Ala Glu Lys Tyr Tyr Lys Arg Trp Lys A.sn Glu Asn His Val Phe Pro 20 " 25 30
Asp Ala He Gly His His He Gin Asn Val Thr Val His Glu Gly Glu
35 40 45
His Asp Ser His Gly Ser He A.rg Ser Trp Asn Tyr Thr Trp Asp Gly 50 55 60 Lys Glu Glu Val Phe Lys Glu Arg Arg Glu He Asp Asp Glu Thr Lys
65 70 " 75 80
Thr Leu Thr Leu Arg Gly Leu Glu Gly His Val Met Glu Gin Leu Lys
85 90 95
Val Tyr Asp Val Val Tyr Gin Phe He Pro Lys Ser Glu Asp Thr Cys 100 105 110
He Gly Lys He Thr Leu He Trp Glu Lys Arg A.sn A.sp A.sp Ser Pro
115 120 125
Glu Pro Ser Gly Tyr Met Lys Phe Val Lys Ser Leu Val A.la Asp Met 130 135 140 Gly A.sn His Val Ser Lys Thr
145 150
(2) INFORMATION FOR SEQ ID NO: 472: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1730 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..1730
(D) OTHER INFORMATION: / Ceres Seq. ID 2050901 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 472: atcgcgtgtt actcctttct aaaggaacca ttgtatatca tggaaggctt gacttacttg 60 aagcattctt gctctccaag ggattcacgg ttccttctca gctgaattct cttgagtacg 120 ctatggagat acttcagaac atccgtgatc cctacgaaaa cgccaacatt gctcttccag 180 accactgccc tgaaagtaaa aaacagaacc aaaaacagag cattgttcga tataaaagct 240 cgagaatcac cgaaataagc cttctctcta gcaggttttg gaagatcata taccgtacaa 300 ggcagttgct tctaacaaac atcttagaat ctcttgtagt cggtcttgtc ttaggcacta 360 tctaccttaa tatcggaact ggcaaagaag gaatcaggaa acgatttggc cttttcgcat 420 tcaccctcac attcctcctc tcctccacta cccaaaccct tccaatattc attgatgaac 480 gacctattct tctccgagaa acctcaagcg gactctacag actctcctct cacattcttg 540 caaacacttt ggttttcttg ccatacttgc tactcatcgc aatcatctac tctgtctcac 600 tctatttcct tgtaggactc tgcttttcat ggcaagctct cgcctacttt gtgctcgtaa 660 tctggatcat tgtcctaatg gctaactctt ttgtactttt cttgagctct ctcgcaccta 720 actacattgc tggaacatct tcagtgacca ttettettge ggctttcttc ttgttctctg 780 gttacttcat ctctaaagag agtcttecea agtactggct cttcatgtac ttcttetcaa 840 tgtacaagta tgcgttggac gcacttctga taaatgagta ctcgtgtctg cacaacaagt 900 gcctggtctg gtttgaggaa gcttctgtga atagctgctt agttactgga ggtgacgtgt 960 tagacaagaa tgggcttcat gagagacaga ggatatatgt gttgggacgt ccgtcattgg 1020 tatccggttt caaacttgag aaacaaggaa acgtttctt gagaagcaag aaaaccctat 1080 gctcccctt tgctcaagct cagtgcctct ttgcagcgaa aαctcaacca acaagacgat 1140 ggaattatcc gagtattaat tgtgatettg tcgtccttt tatcagatta tctcagagaa 1200 caatcgcaga gagatctgca aatacctttt eaaagctagt ggaaccagag ggagtatgct 1260 ttgctaagaa ggatttcaat ctcccaaagc atccgttgat tgatgtacca aacctgcaag 1320 tqattaagct catgcagagt ttcaagtcca aggagtacgt tagggagaca tttgcgtgga 1380 tgcattatta ttggtttctg actaatgaag gaattgagtt cttgagaact tatcttaacc 1440 ttccttccga tgttgtccet gctactttga agaagtctgc taagcccggt ggtcgtccct 1500 ttggtggccc acctggtgat cgccaaagag gaccacctcg ctctgatgga gaccgtccca 1560 gatttggtga ccgtgatgga taccgtggag gcccacgtgg tggtgatgag aagggtggag 1620 ctccagctga tttccagccg tctttccaag gaggtggtgg taggcctggt tttggccgtg 1680 gtgcaggcgg ttacagtgca gcagcaccat ctggttcagg gttcccttga (2) INFORMATION FOR SEQ ID NO: 473: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 575 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..575
(D) OTHER INFORMATION: , Ceres Seq. ID 2050902 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 473:
Arg Val Leu Leu Leu Ser Lys Gly Thr He Val Tyr His Gly Arg Leu 1 5 10 15 Asp Leu Leu Glu Ala Phe Leu Leu Ser Lys Gly Phe Thr Val Pro Ser 20 25 30
Gin Leu Asn Ser Leu Glu Tyr Ala Met Glu He Leu Gin Asn He A.rg
35 40 45
Asp Pro Tyr Glu Asn Ala Asn He Ala Leu Pro Asp His Cys Pro Glu 50 55 60
Ser Lys Lys Gin A.sn Gin Lys Gin Ser He Val Arg Tyr Lys Ser Ser 65 70 75 80
A.rg He Thr Glu He Ser Leu Leu Ser Ser Arg Phe Trp Lys He He 85 90 95 Tyr Arg Thr Arg Gin Leu Leu Leu Thr A.sn He Leu Glu Ser Leu Val
100 105 110
Val Gly Leu Val Leu Gly Thr He Tyr Leu Asn He Gly Thr Gly Lys
115 120 * 125
Glu Gly He Arg Lys Arg Phe Gly Leu Phe Ala Phe Thr Leu Thr Phe 130 135 140
Leu Leu Ser Ser Thr Thr Gin Thr Leu Pro He Phe He Asp Glu Arg 145 150 155 160 Pro He Leu Leu Arg Glu Thr Ser Ser Gly Leu Tyr Arg Leu Ser Ser
165 170 175
His He Leu Ala Asn Thr Leu Val Phe Leu Pro Tyr Leu Leu Leu He 180 185 190 Ala He He Tyr Ser Val Ser Leu Tyr Phe Leu Val Gly Leu Cys Phe 195 200 205
Ser Trp Gin Ala Leu Ala Tyr Phe Val Leu Val He Trp He He Val
210 215 220
Leu Met Ala Asn Ser Phe Val Leu Phe Leu Ser Ser Leu Ala Pro Asn 225 230 235 240
Tyr He Ala Gly Thr Ser Ser Val Thr He Leu Leu Ala Ala Phe Phe
245 250 255
Leu ?he Ser Gly Tyr Phe He Ser Lys Glu Ser Leu Pro Lys Tyr Trp 260 265 270 Leu Phe Met Tyr Phe Phe Ser Met Tyr Lys Tyr Ala Leu Asp Ala Leu 275 ' 280 285
Leu He Asn Glu Tyr Ser Cys Leu His Asn Lys Cys Leu Val Trp Phe
290 295 300
Glu Glu Ala Ser Val Asn Ser Cys Leu Val Thr Gly Gly Asp Val Leu 3D5 310 315 320
Asp _ys Asn Gly Leu His Glu A.rg Gin Arg He Tyr '.'al Leu Gly Arg
325 330 335
Pre Ser Leu Val Ser Gly Phe Lys Leu Glu Lys Gin Gly He A.rg Phe 340 345 350 Leu A.rg Ser Lys Lys Thr Leu Leu Leu Fro Phe Ala Gin Ala Gin Cys 355 360 365
Leu Phe Ala Ala Lys A.la Gin Pro Thr A.rg A.rg Trp Asn Tyr Pro Ser
370 375 " ' 380
He A.sn Cys Asp Leu Val Arg Pro Phe He Arg Leu Ser Gin Arg Thr 385 390 395 " 400
He Ala Glu Arg Ser Ala Asn Thr Phe Ser Lys Leu Val Glu Pro Glu
405 410 415
Gly Val Cys Phe Ala Lys Lys Asp Phe Asn Leu Pro Lys His Pro Leu 420 425 430 He Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser Phe Lys 435 440 445
Ser Lys Glu Tyr Val A.rg Glu Thr Phe A.la Trp Met His Tyr Tyr Trp
450 " 455 " 460
Phe Leu Thr Asn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu Asn Leu 465 470 475 480
Pro Ser Asp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly
485 490 495
Gly A.rg Pro Phe Gly Gly Pro Pro Gly Asp Arg Gin Arg Gly Pro Pro 500 505 510 Arg Ser Asp Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg 515 520 525
Gly Gly Pro Arg Gly Gly Asp Glu Lys Gly Gly A.la Pro Ala Asp Phe
530 535 540
Gin Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro Gly Phe Gly Arg Gly 545 550 555 " 560
Ala Gly Gly Tyr Ser Ala A.la Ala Pro Ser Gly Ser Gly Phe Pro 565 570 575
(2) INFORMATION FOR SEQ ID NO: 474: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 535 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide iix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..535 (D) OTHER INFORMATION: / Ceres Seq. ID 2050903 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 474: Met Glu He Leu Gin Asn He Arg Asp Pro Tyr Glu Asn Ala Asn He 1 5 10 15 Ala Leu Pro Asp His Cys Pro Glu Ser Lys Lys Gin Asn Gin Lys Gin 20 25 30
Ser He Val Arg Tyr Lys Ser Ser Arg He Thr Glu He Ser Leu Leu
35 40 45
Ser Ser Arg Phe Trp Lys He He Tyr Arg Thr Arg Gin Leu Leu Leu 50 55 " 60
Thr Asn He Leu Glu Ser Leu Val Val Gly Leu Val Leu Gly Thr He 65 70 75 80
Tyr Leu Asn He Gly Thr Gly Lys Glu Gly He Arg Lys Arg Phe Gly 85 90 95 Leu Phe Ala Phe Thr Leu Thr Phe Leu Leu Ser Ser Thr Thr Gin Thr
100 105 110
Leu Pro He Phe He Asp Glu A.rg Pro He Leu Leu Arg Glu Thr Ser
115 120 125
Ser Gly Leu Tyr Arg Leu Ser Ser His He Leu Ala Asn Thr Leu Val 130 135 140
Phe Leu Pro Tyr Leu Leu Leu He Ala He He Tyr Ser Val Ser Leu
145 150 155 160
Tyr Phe Leu Val Gly Leu Cys Phe Ser Trp Gin Ala Leu A.la Tyr Phe
165 170 175 Val Leu Val He Trp He He Val Leu Met Ala Asn Ser Phe Val Leu
180 185 190
Phe Leu Ser Ser Leu Ala Pre Asn Tyr He Ala Gly Thr Ser Ser Val
195 200 205
Thr He Leu Leu Ala Ala Phe Phe Leu Phe Ser Gly Tyr Phe He Ser 210 215 220
Lys Glu Ser Leu Pro Lys Tyr Trp Leu Phe Met Tyr Phe Phe Ser Met
225 230 235 240
Tyr Lys Tyr Ala Leu Asp Ala Leu Leu He A.sn Glu Tyi Ser Cys Leu
245 250 255 His Asn Lys Cys Leu Val Trp Phe Glu Glu Ala Ser Val Asn Ser Cys
260 265 270
Leu Val Thr Gly Gly Asp Val Leu A.sp Lys Asn Gly Leu His Glu Arg
275 280 " ' 285
Gin Arg He Tyr Val Leu Gly Arg Pro Ser Leu Val Ser Gly Phe Lys 290 295 ' 300
Leu Glu Lys Gin Gly He Arg Phe Leu Arg Ser Lys Lys Thr Leu Leu
305 310 315 320
Leu Pro Phe Ala Gin Ala Gin Cys Leu Phe Ala Ala Lys Ala Gin Pro
325 330 335 Thr Arg Arg Trp Asn Tyr Pro Ser He Asn Cys Asp Leu Val Arg Pro
340 345 350
Phe He Arg Leu Ser Gin Arg Thr He Ala Glu Arg Ser Ala Asn Thr
355 360 365
Phe Ser Lys Leu Val Glu Pro Glu Gly Val Cys Phe Ala Lys Lys Asp 370 375 380
Phe A.sn Leu Pro Lys His Pro Leu He Asp Val Pro Asn Leu Gin Val
385 390 395 400
He Lys Leu Met Gin Ser Phe Lys Ser Lys Glu Tyr Val A.rg Glu Thr
405 410 415 Phe Ala Trp Met His Tyr Tyr Trp Phe Leu Thr Asn Glu Gly He Glu
420 425 430
Phe Leu Arg Thr Tyr Leu Asn Leu Pro Ser Asp Val Val Pro Ala Thr
435 440 445
Leu Lys Lys Ser Ala Lys Pro Gly Gly Arg Pro Phe Gly Gly Pro Pro 450 455 460
Gly Asp Arg Gin Arg Gly Pro Pro Arg Ser Asp Gly Asp Arg Pro Arg 465 ' 470 475 480 Phe Gly Asp Arg Asp Gly Tyr Arg Gly Gly Pro Arg Gly Gly Asp Glu
485 490 495
Lys Gly Gly Ala Pro Ala Asp Phe Gin Pro Ser Phe Gin Gly Gly Gly 500 505 510 Gly Arg Pro Gly Phe Gly Arg Gly Ala Gly Gly Tyr Ser Ala Ala Ala 515 520 525
Pro Ser Gly Ser Gly Phe Pro 530 535
(2) INFORMATION FOR SEQ ID NO:475: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 350 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..350
(D) OTHER INFORMATION: Ceres Seq. ID 2050904 ;xi) SEQUENCE DESCRIPTION: SEQ ID MO: 475:
Met Ala Asn Ser Phe Val Leu Phe Leu Ser Ser Leu Ala Pro Asn Tyr 1 5 10 15
He Ala Gly Thr Ser Ser al Thr He Leu Leu A.la Ala Phe Phe Leu 20 25 30 Phe Ser Gly Tyr Phe He Ser Lys Glu Ser Leu Pro Lys Tyr Trp Leu 35 40 45
Phe Met Tyr Phe Phe Ser Met Tyr Lys Tyr Ala Leu Asp Ala Leu Leu
50 55 60
He Asn Glu Tyr Ser Cys Leu His Asn Lys Cys Leu Val Trp Phe Glu 65 ' 70 " 75 80
Glu Ala Ser Val Asn Ser Cys Leu Val Thr Gly Gly Asp Val Leu Asp
85 90 95
Lys Asn Gly Leu His Glu Arg Gin Arg He Tyr \ 1 Leu Gly Arg Pro 100 105 110 Ser Leu Val Ser Gly Phe Lys Leu Glu Lys Gin Gly He Arg Phe Leu 115 120 125
Arq Ser Lys Lys Thr Leu Leu Leu Pre Phe Ala Gin A.la Gin Cys Leu
130 " 135 140
Phe Ala Ala Lys Ala Gin Pro Thr Arg Arg Trp Asn Tyr Pro Ser He 145 150 155 160
A.sn Cys Asp Leu Val Arg Pro Phe He A.rg Leu Ser Gin Arg Thr He
165 170 175
Ala Glu Arg Ser Ala Asn Thr Phe Ser Lys Leu Val Glu Pro Glu Gly 180 185 190 Val Cys Phe Ala Lys Lys Asp Phe Asn Leu Pro Lys His Pro Leu He 195 200 205
Asp Val Pro Asn Leu Gin Val He Lys Leu Met Gin Ser Phe Lys Ser
210 215 220
Lys Glu Tyr Val Arg Glu Thr Phe Ala Trp Met His Tyr Tyr Trp Phe 225 230 235 240
Leu Thr A.sn Glu Gly He Glu Phe Leu Arg Thr Tyr Leu Asn Leu Pro
245 250 255
Ser Asp Val Val Pro Ala Thr Leu Lys Lys Ser Ala Lys Pro Gly Gly 260 265 270 Arg Pro Phe Gly Gly Pro Pro Gly Asp Arg Gin Arg Gly Pro Pro Arg 275 280 285
Ser Asp Gly Asp Arg Pro Arg Phe Gly Asp Arg Asp Gly Tyr Arg Gly
290 295 ' 300
Gly Pro Arg Gly Gly Asp Glu Lys Gly Gly Ala Pro Ala Asp Phe Gin 305 " 310 315 320
Pro Ser Phe Gin Gly Gly Gly Gly Arg Pro Gly Phe Gly Arg Gly Ala 325 330 335 Gly Gly Tyr Ser Ala Ala Ala Pro Ser Gly Ser Gly Phe Pro 340 345 350
(2) INFORMATION FOR SEQ ID NO: 476: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 535 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A.) NAME/KEY: -
(B) LOCATION: 1..535 lD) OTHER INFORMATION: / Ceres Seq. ID 2051325 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 476: gctacataac tcaaagtaac aaacataeae atataacata tagaaagatc gaaaacaaaa 60 gatcgggatg agtatggctc caaagacctc aactacactt gctttattcc ttgtgaecaa 120 tattctcttc ctcaacctca ttaccctgag ttgcgcagac aatacttgcc caagagacgt 180 tetcaaactt tcgacatgct cgaatgttct caacctcatc aacttgaage teggggcacc 240 agctatgagg ccttgttgct ctattctctt tggtctaatt gatctcgatg ttgctgtttg 300 cctttgcacc gcgctcaagc tcagccttct ggcatcacc atcgacactc ctattcacct 360 taacttggct ettaacgcct gtggaggtac ccttcctgat ggattccgtt gcccaacata 420 gctacaatat attcatattt tctatctatg ttcttgaatt ggttttgtct aacatccaaa 480 ttcaaacct aaattcatgt ataagcaaat aacaagtaaa attaagactt ttatg (2) INFORMATION FOR SEQ ID NO: 477: (i) SEQUENCE CHARACTERISTICS:
..A) LENGTH: 117 amino acids '3) TYPE: amino acid
(C) STRANDEDNESS: vD) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..117
> D) OTHER INFORMATION: / Ceres Seq. ID 2051326 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 477:
Met Ser Met Ala Pro Lys Thr Ser Thr Thr Leu Ala Leu Phe Leu Val 1 5 10 15
Thr Asn He Leu Phe Leu Asn Leu He Thr Leu Ser Cys A.la Asp Asn 20 25 30 Thr Cys Pro A.rg Asp Val Leu Lys Leu Ser Thr Cys Ser Asn Val Leu 35 40 45
Asn Leu He Asn Leu Lys Leu Gly Ala Pro Ala Met Arg Pro Cys Cys
50 55 60
Ser He Leu Phe Gly Leu He Asp Leu Asp Val Ala Val Cys Leu Cys 65 70 75 80
Thr Ala Leu Lys Leu Ser Leu Leu Gly He Thr He Asp Thr Pro He
85 90 95
His Leu Asn Leu Ala Leu Asn Ala Cys Gly Gly Thr Leu Pro Asp Gly 100 105 110 Phe Arg Cys Pro Thr 115 (2) INFORMATION FOR SEQ ID NO: 478: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: / Ceres Seq. ID 2051327 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 478: Met Ala Pro Lys Thr Ser Thr Thr Leu Ala Leu Phe Leu Val Thr Asn 1 5 10 15
He Leu Phe Leu Asn Leu He Thr Leu Ser Cys Ala Asp Asn Thr Cys 20 25 30
Pro A.rg Asp Val Leu Lys Leu Ser Thr Cys Ser Asn Val Leu Asn Leu
35 40 45
He A.sn Leu Lys Leu Gly Ala Pro Ala Met Arg Pro Cys Cys Ser He 50 55 60 Leu Phe Gly Leu He Asp Leu Asp Val Ala Val Cys Leu Cys Thr Ala 65 70 "5 30
Leu Lys Leu Ser Leu Leu Gly He Thr He A.sp Thr Pro He His Leu
85 90 95
A.sn Leu A.la Leu Asn Ala Cys Gly Gly Thr Leu Pro Asp Gly Phe Arg 100 105 110
Cys Fro Thr 115 ι'2) INFORMATION FOR SEQ ID NO: 479: 'i; SEQUENCE CHARACTERISTICS: Α) LENGTH: ^ ammo acids VC) STRANDEDNESS: (E) TOPOLOGY: linear ii) MOLECULE TYPE: peptide ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 2051328 'xi) SEQUENCE DESCRIPTION: SEQ ID NO: 479: Met Leu Leu Phe Ala Phe Ala Pro Arg Ser Ser Ser Ala Phe Leu Ala 1 5 10 15
Ser Pro Ser Thr Leu Leu Phe Thr Leu Thr Trp Leu Leu Thr Pro Val
20 25 30
Glu Val Pro Phe Leu Met Asp Ser Val Ala Gin His Ser Tyr Asn He 35 40 45
Phe He Phe Ser He Tyr Val Leu Glu Leu Val Leu Ser A.sn He Gin
50 55 60
He Ser A.sn Leu Asn Ser Cys He Ser Lys 65 70 (2) INFORMATION FOR SEQ ID NO: 480: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 517 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..517 (D) OTHER INFORMATION: / Ceres Seq. ID 2051633
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 480: eataaeccte ttggaaagag tctcaacact tgcagagaaa aagaacaagg aagatccegg 60 aaaatggcaa cggcgattgt acgttcaget cttteccgag cagtgactcg cgcagctccg 120 aagacatccg tcgctcctaa gcgaaacttt tcctcttccg ccggccatga cgatgcttat 180 gaagctgcga agtgggagaa gataacttat ctgggtattg ctagttgcac tgctctagct 240 gtctatgttt tatccaaggg ccatcatcac ggcgaagacc ctcctgecta tecgcatatg 300 cacatccgca acaaggagtt tccttggggt ccggatggtc tgtttgaggt gaagcacaac 360 aaagagcact gagtcttgcg tggtcataat aacgtcttct tggtttattt gaaaggctaa 420 aatgttttac cgtatttgtt ctcaccgttt gtcaacgatt tgctactcca atctcttttc 480 ttttgttggg aaataaaagt taatactttg cttggtc (2) INFORMATION FOR SEQ ID NO : 481 : (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 123 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..123
(D) OTHER INFORMATION: / Ceres Seq. ID 2051634 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 481:
His A.sn Pro Leu Gly Lys Ser Leu Asn Thr Cys A.rg Glu Lys Glu Gin 1 5 10 15
Gly A.rg Ser A.rg Lys Met Ala Thr A.la He Val Arg Ser Ala Leu Ser 20 25 30 Arg A.la Val Thr Arg Ala Ala Pro Lys Thr Ser Val Ala Pro Lys Arg 35 40 45
Asn Fhe Ser Ser Ser Ala Gly His A.sp Asp Ala Tyr Glu Ala Ala Lys
50 55 60
Trp Glu Lys He Thr Tyr Leu Gly He Ala Ser Cys Thr Ala Leu Ala 65 70 ^5 80
"al Tyr Val Leu Ser Lys Gly His His His Gly Glu Asp Pre Pro Ala
35 90 95
Tyr Fro His Met His He A.rg Asn Lys Glu Phe Pro Trp Gly Pro Asp 100 105 110 Gly Leu Phe Glu Val Lys His A.sn Lys Glu His 115 120
(2) INFORMATION FOR SEQ ID MO:482: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..102
(D) OTHER INFORMATION: / Ceres Seq. ID 2051635 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 82: Met Ala Thr Ala He Val Arg Ser Ala Leu Ser Arg A.la Val Thr Arg 1 5 10 " 15
A.la A.la Pro Lys Thr Ser Val Ala Pro Lys Arg Asn Phe Ser Ser Ser
20 25 30
Ala Gly His Asp Asp Ala Tyr Glu Ala A.la Lys Trp Glu Lys He Thr 35 40 45 Tyr Leu Gly He Ala Ser Cys Thr Ala Leu Ala Val Tyr Val Leu Ser 50 55 60
Lys Gly His His His Gly Glu Asp Pro Pro Ala Tyr Pro His Met His 65 70 75 80
He Arg Asn Lys Glu Phe Pro Trp Gly Pro Asp Gly Leu Phe Glu Val 85 " 90 95
Lys His Asn Lys Glu His
100 (2) INFORMATION FOR SEQ ID NO: 483: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 410 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..410 (D) OTHER INFORMATION: / Ceres Seq. ID 2051906 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 483: ttccttcttt ttcacatcta cccaaaattc caaaacacca tcgatttttt gctctcttga 60 aatgtgtctt tttatgtcca attcttctct tccaactaaa ccgaaccgga aaaccaggtt 120 cggagatcgg tgtttactga tggccaaaca gcaacgaacc cgactttaca tacttcgacg 180 atgtgtctec atgctgcttt gctggcacga ccactetatt tctgattagt ttgattcatg 240 aaceggacgg accaagaagt agaaatcaga agaatgtgat gtcatttaga gtttttcttg 300 ttttctttta gaactcttca aggaatcttt tgtaattgaa gaagactcta aggattgggc 360 cttttgggcc tttgtacata ttgtgtaaat aacatatgaa ctttttttac (2) INFORMATION FOR SEQ ID NO: 484: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 75 amino acids
(B) TYPE: amino acid .C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide ix) FEATURE:
(A) NAME/KEY: peptide Ε) LOCATION: 1..75 D) OTHER INFORMATION: / Ceres Seq. ID 205190' y.H SEQUENCE DESCRIPTION: SEQ ID NO: 484: Ser Fne Phe Phe Thr Ser Thr Gin Asn Ser Lys Thr_ Pro Ser He Phe 1 5 10 15
Cys Ser Leu Glu Met Cys Leu Phe Met Ser Asn r Ser Leu Pro Thr 20 25 30
Lys Pro Asn A.rg Lys Thr A.rg Phe Gly A.sp A.rg Cy 5s Leu Leu Met Ala
35 40 45
Lys Gin Gin Arg Thr A.rg Leu Tyr He Leu Arg A.rg Cys Val Ser Met 50 55 60 Leu Leu Cys Trp His Asp His Ser He Ser Asp 65 70 75
(2) INFORMATION FOR SEQ ID NO: 85: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 55 amino acids (B) TYPE: amino acid ι'C) STRANDEDNESS:
;D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide 'ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..55 (D) OTHER INFORMATION: / Ceres Seq. ID 2051908
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:485: Met Cys Leu Phe Met Ser Asn Ser Ser Leu Pro Thr Lys Pro Asn Arg 1 5 10 15
Lys Thr A.rg Phe Gly A.sp Arg Cys Leu Leu Met Ala Lys Gin Gin Arg
20 25 30
Thr A.rg Leu Tyr He Leu Arg Arg Cys Val Ser Met Leu Leu Cys Trp 35 40 45 His Asp His Ser He Ser Asp 50 55
(2) INFORMATION FOR SEQ ID NO: 486: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 51 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear fii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..51 (D) OTHER INFORMATION: / Ceres Seq. ID 2051909 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 486: Met Ser Asn Ser Ser Leu Pro Thr Lys Pro Asn Arg Lys Thr Arg Phe 1 5 10 15
Gly Asp Arg Cys Leu Leu Met Ala Lys Gin Gin Arg Thr Arg Leu Tyr 20 25 30
He Leu Arg Arg Cys Val Ser Met Leu Leu Cys Trp His Asp His Ser
35 40 45
He Ser A.sp 50 (2) INFORMATION FOR SEQ ID NO: 487: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 719 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..719 I'D) OTHER INFORMATION: ' Ceres Seq. ID 2352403
( i) SEQUENCE DESCRIPTION: SEQ ID 110:48": acaaaccatt caaagacata caaaataatt gagttttttt tttaattaga aacaaatggg 60 gttgagtggt gttcttcatg tggaggttga ggttaagtct ccggctgaaa agttctgggt 120 agcccttggc gacggcatca atctcttccc caaagctttc cctaacgact acaaaaccat 180 ccaagttcta gccggcgatg gcaacgctcc tggctccatt cgcctcatta cttatggaga 240 aggatctcca ctggtgaaga tatcggcgga gaggatcgaa gcagtggatt tggagaacaa 300 aagcatgtcg tacagcatca ttggcggaga aatgttggag tactacaaaa ccttcaaagg 360 aaccatcacc gttatcecta aggatggtgg tagccttctg aaatggtctg gtgagtttga 420 gaagaccgcc catgagatcg atgatccaca tgtcatcaag gactttgctg tcaagaactt 480 caaagagata gatgagtatc ttcttaagca aactagtgcc taacactaga acctttaaat 540 tatataagag ggttcgaccg tctctataag atttttetaa ttaagaagtt gaataaagtg 600 gaaccccttt atgaatatcc acgttttatg atttcggagt ttatgcagcc tagtaggcca 660 taagcttttt acaaaagcca atttagtcga acattttgaa aaaatcgaac cttgtggta (2) INFORMATION FOR SEQ ID NO: 488: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 155 amino acids (B) TYPE: amino acid (C; STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..155
(D) OTHER INFORMATION: / Ceres Seq. ID 2052404 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 488:
Met Gly Leu Ser Gly Val Leu His Val Glu Val Glu Val Lys Ser Pro 1 5 10 15
Ala Glu Lys Phe Trp Val Ala Leu Gly Asp Gly He Asn Leu Phe Pro 20 25 30 Lys Ala Phe Pro Asn Asp Tyr Lys Thr He Gin Val Leu Ala Gly Asp 35 40 45
Gly Asn Ala Pro Gly Ser He Arg Leu He Thr Tyr Gly Glu Gly Ser
50 55 60
Pro Leu Val Lys He Ser Ala Glu Arg He Glu Ala Val Asp Leu Glu 65 70 75 80
Asn Lys Ser Met Ser Tyr Ser He He Gly Gly Glu Met Leu Glu Tyr
85 90 95
Tyr Lys Thr Phe Lys Gly Thr He Thr Val He Pro Lys Asp Gly Gly 100 105 110 Ser Leu Leu Lys Trp Ser Gly Glu Phe Glu Lys Thr Ala His Glu He 115 120 125
Asp Asp Pro His Val He Lys Asp Phe Ala Val Lys Asn Phe Lys Glu 130 135 140
He Asp Glu Tyr Leu Leu Lys Gin Thr Ser Ala 145 150 155
(2) INFORMATION FOR SEQ ID NO: 489: 5 i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 739 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single , ' TOPOLOGY: linear
10 .ii MOLECULE TYPE: DNA genomic)
-x, FEATURE:
(A.) NAME/KEY: -
{ 3 ) LOCATION: 1..739 OTHER INFORMATION: ' Ceres Seq. ID 2053545
15 xij SEQUENCE DESCRIPTION: SEQ ID NO: 489: at t agtac attgttgacc atctttttcg tatagactac tatctctgat ctcttgcgag 60 ttaaqtcaqt aactaggaaa attcagaagc qctctcaatc tcaaaaatat ccatggcggc 120 qattacaqaa tttctaccaa aagagtaeqq atatqtcgtt ctcgtcctcg tcttctactg 180 '""tcetcaac etctggatgg tqctcaaαt cqgcaqagct cgcaaaaggt acaacqtccc 240
__.0 tatecaact etatatqcaa taαaatcaαa αaacaaaoat αctaagctct tcaactgtgt 300 -eeoaqagqa eatcaaαact c^t gaαa αatαccaatq tatt catac gatgatcct 360 eggtαggatg aagcaccctt qtatcrqtac tqαccttggt "tqctttaca acqttagccg 420 attettetac tttaaaggtt atgctactqg agatcccatg aagcgtctta cgatcgggaa 480 atacggtttc ttggggttcc tagqtctqat qatatgtacc atctcgtttg gtgtcactct 540
25 gatcettgct tgagctactc qtttctqgqg ttaatgattc tctggtttαc tcgaagaata 600 agaaccaat gettgtaagc tgtccacaaa acttgtgtaa tactttagag tttgtcactt 660 ttaaaagttt gtaataaatc atggettcat agaacagttg aaatttcaca tccgtagacg 720 ttaa aaaga tttgaatta (2) INFORMATION FOR SEQ ID NO: 490:
30 l) SEQUENCE CHARACTERISTICS : A) LENGTH: 146 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear 35 .ii) MOLECULE TYPE: peptide
.ix, FEATURE:
'A^ NAME/KEY: peptide >BV LOCATION: 1..146 D, OTHER INFORMATION: Ceres Seq. ID 2053546 40 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 490:
Met Ala Ala He Thr Glu Phe Leu Pro Lys Glu Tyr Gly Tyr Val Val 1 5 10 15
Leu al Leu Val Phe Tyr Cys Phe Leu Asn Leu Trp Met Gly Ala Gin 20 25 30
45 Val Gly Arq Ala Arq Lys Arq Tyr Asn Val Pro Tyr Pro Thr Leu Tyr 35 40 45
Ala He Glu Ser Glu Asn Lys A.sp Ala Lys Leu Phe Asn Cys Val Gin
50 55 60
Arg Gly His Gin Asn Ser Leu Glu Met Met Pro Met Tyr Phe He Leu 50 65 70 75 80
Met He Leu Gly Gly Met Lys His Pro Cys He Cys Thr Gly Leu Gly
85 90 95
Leu Leu Tyr Asn Val Ser Arg Phe Phe Tyr Phe Lys Gly Tyr Ala Thr 100 105 110
55 Gly Asp Pro Met Lys Arg Leu Thr He Gly Lys Tyr Gly Phe Leu Gly 115 120 125
Leu Leu Gly Leu Met He Cys Thr He Ser Phe Gly Val Thr Leu He
130 135 140
Leu Ala 60 145
(2) INFORMATION FOR SEQ ID NO: 491: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 118 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..118
(D) OTHER INFORMATION: / Ceres Seq. ID 2053547 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 491:
Met Gly A.la Gin Val Gly A.rg Ala Arg Lys A.rg Tyr A.sn Val Pro Tyr 1 5 10 15
Pro Thr Leu Tyr Ala He Glu Ser Glu Asn Lys Asp Ala Lys Leu Phe 20 25 30 Asn Cys Val Gin Arg Gly His Gin Asn Ser Leu Glu Met Met Pro Met 35 40 45
Tyr Phe He Leu Met He Leu Gly Gly Met Lys His Pro Cys He Cys
50 55 60
Thr Gly Leu Gly Leu Leu Tyr Asn Val Ser Arg Phe Phe Tyr Phe Lys 65 70 75 " 80
Gly Tyr Ala Thr Gly Asp Pre Met Lys A.rg Leu Thr He Gly Lys Tyr
85 90 95
Gly Phe Leu Gly Leu Leu Gly Leu Met He Cys Thr He Ser Phe Gly 100 105 110 Val Thr Leu He Leu Ala 115 (2) INFORMATION FOR SEQ ID NO: 492: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 2053548 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 492: Met Met Pro Met Tyr Phe He Leu Met He Leu Gly Gly Met Lys His 1 5 10 15
Pro Cys He Cys Thr Gly Leu Gly Leu Leu Tyr Asn Val Ser Arg Phe
20 25 30
Phe Tyr Phe Lys Gly Tyr Ala Thr Gly Asp Pro Met Lys Arg Leu Thr 35 40 45 He Gly Lys Tyr Gly Phe Leu Gly Leu Leu Gly Leu Met He Cys Thr 50 55 60
He Ser Phe Gly Val Thr Leu He Leu Ala 65 " 70
(2) INFORMATION FOR SEQ ID NO: 493: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 681 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..681
(D) OTHER INFORMATION: / Ceres Seq. ID 2053884 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 493: ccatccaaaa aaaacaaaac aaaaaattat attcaagaga aaaaggaaaa aatgaatttc 60 atctccgatc aggtaaagaa actctcaagc tcaacaccag aggagccaga ccacaacaag 120 ccagtcgaag gaaccgaaac agctacaaga ccagctacca acgccgagct catggcaagt 180 gccaaggttg tagctgaagc tgcteaagcc gcagctcgta acgaatcaga caaactegac 240 aagggtaaag tcgccggagc ctctgctgat atcttagacg ctgccgagaa atacggtaag 300 ttcgatgaaa agagtagcac tggtcagtac ctcgacaagg ctgagaagta tctcaacgac 360 tacgagtcgt cacactccac cggtgctggt ggtcctcctc ctccgacgag tcaggctgag 420 ccagcaagtc agcctgagcc ggcggctaag aaagacgatg aagagtctgg tggtgggctt 480 ggaggttatg ccaagatggc tcaaggtttc ttgaagtgat ttgatcttta attgttgttc 540 atcattttcg taataataaa ttaaataact agtatcgttt gtgactagtt tatgttgctt 600 cgtttatgtt tatggggagt gacgagtgag tgtaataact tctggtgatc atgaatctaa 660 tccatctttg ttgtgattat g
(2) INFORMATION FOR SEQ ID NO: 494: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 172 amino acids ,C) STRANDEDNESS:
.D) TOPOLOGY: linear
(ii) MOLECULE TYPE: pept :ide
(ix) FEATURE:
■A) NAME/KEY: peptide
B) LOCATION: 1..I .72
2 ] OTHER INFORMATION: : Ceres ; Seq. ID 2053885
xi J SEQUENCE DESCRIPTION: SEQ ID NO: 494:
Pro Ser Lys Lys A.sn Lys Thr Lys Asn Tyr He Gin Glu Lys Lys Glu
1 5 10 15
Lys Met Asn Phe He Ser A.sp Gin Val Lys Lys Leu Ser Ser Ser Thr 20 25 30
Pro Glu Glu Pro Asp His A.sn Lys Pro Val Glu Gly Thr Glu Thr Ala 35 40 45
Thr Arg Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val 50 " 55 60
Ala Glu A.la Ala Gin Ala A.la Ala Arg Asn Glu Ser Asp Lys Leu Asp 65 70 75 80
Lys Gly Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ala Glu 85 90 95 Lys Tyr Gly Lys Phe Asp Glu Lys Ser Ser Thr Gly Gin Tyr Leu Asp
100 105 110
Lys Ala Glu Lys Tyr Leu A.sn A.sp Tyr Glu Ser Ser His Ser Thr Gly 115 120 125
Ala Gly Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin 113300 135 140
Pro Glu Pro Ala Ala Lys Lys Asp Asp Glu Glu Ser Gly Gly Gly Leu 145 150 155 160
Gly Gly Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 165 ' 170 (2) INFORMATION FOR SEQ ID NO: 495: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 155 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..155 (D) OTHER INFORMATION: / Ceres Seq. ID 2053886
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 495: Met Asn Phe He Ser Asp Gin Val Lys Lys Leu Ser Ser Ser Thr Pro 1 5 10 15
Glu Glu Pro Asp His Asn Lys Pro Val Glu Gly Thr Glu Thr Ala Thr 20 25 30
Arg Pro Ala Thr Asn Ala Glu Leu Met Ala Ser Ala Lys Val Val Ala 35 40 45 Glu Ala Ala Gin Ala Ala Ala Arg Asn Glu Ser Asp Lys Leu Asp Lys
50 55 60
Gly Lys Val Ala Gly Ala Ser Ala Asp He Leu Asp Ala Ala Glu Lys 65 70 75 80 Tyr Gly Lys Phe Asp Glu Lys Ser Ser Thr Gly Gin Tyr Leu Asp Lys
85 90 95
Ala Glu Lys Tyr Leu Asn Asp Tyr Glu Ser Ser His Ser Thr Gly Ala
100 105 110
Gly Gly Pro Pro Pro Pro Thr Ser Gin Ala Glu Pro Ala Ser Gin Pro " 115 120 125
Glu Pro Ala Ala Lys Lys Asp A.sp Glu Glu Ser Gly Gly Gly Leu Gly
130 135 140
Gly Tyr Ala Lys Met Ala Gin Gly Phe Leu Lys 145 150 155 (2) INFORMATION FOR SEQ ID NO: 496: fi) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 115 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide 'ix) FEATURE:
.A) NAME/KEY: peptide (B) LOCATION: 1..115 (D) OTHER INFORMATION: / Ceres Seq. ID 2053887
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 496: Met Ala Ser Ala Lys Val Val Ala Glu A.la Ala Gin Ala Ala Ala A.rg 1 5 10 15
Asn Glu Ser Asp Lys Leu Asp Lys Gly Lys Val Ala Gly Ala Ser Ala 20 25 ' 30
Asp He Leu Asp Ala Ala Glu Lys Tyr Gly Lys Phe Asp Glu Lys Ser
35 40 45
Ser Thr Gly Gin Tyr Leu Asp Lys Ala Glu Lys Tyr Leu A.sn Asp Tyr 50 55 60 Glu Ser Ser His Ser Thr Gly Ala Gly Gly Pro Pro Pro Pro Thr Ser 65 70 75 80
Gin A.la Glu Pro Ala Ser Gin Pro Glu Pro A.la Ala Lys Lys A.sp Asp
85 90 95
Glu Glu Ser Gly Gly Gly Leu Gly Gly Tyr A.la Lys Met Ala Gin Gly 100 105 110
Phe Leu Lys 115 (2) INFORMATION FOR SEQ ID NO: 497: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 797 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..797
(D) OTHER INFORMATION: / Ceres Seq. ID 2053908 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 497: ttctctcaaa atccataaaa agagagagag ataaataaag agaaaactaa agaagctaga 60 agatggagaa aagtaatgat catgacaagg ctagccacgg cggctccggt ggtggtgcca 120 cggagaagtg ggaggagact agcctcggaa tccgaactgc cgagacaatg ctccggttag 180 ctccggtggg cctttgtgtt gcagcacttg ttgtcatgct taaggactct gagactaatg 240 agttcggttc aatttcttac tccaatctca cagcctttag gtacttggtg cacgcaaatg 300 gaatatgtgc aggctactct cttctatcag cagccattgc agcgatgcct cgttcttctt 360 cgacaatgcc tcgtgtttgg accttctttt gtctcgacca gcttctgacc tacctggttc 420 ttgctgctgg agctgtatca gctgaggttc tatacttggc ttacaatgga gactcagcca 480 ttacttggag cgatgcatgt agctcctatg gcggtttctg tcatagagce aetgcttctg 540 ttataatcac attctttgtg gtttgtttct acatcgttct ctctctaatc tectcttata 600 agctctttac tcgctttgat cctccttcca ttgttgactc cgccaagaat ctcgaagtcg 660 ctgtcttcgg aagttagatc ctccatttgc tcttcaagta catctagttt gtcatgtttc 720 aaatgttgtg tgtttttaac tttggtcaag agaaagaatg cttatgtgtt tgctcttctt 780 tcattgcttt tcttcct
;2) INFORMATION FOR SEQ ID NO: 498: H) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 204 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..204
(D) OTHER INFORMATION: / Ceres Seq. IC 2053909 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 98: Met Glu Lys Ser Asn Asp His Asp Lys Ala Ser His Gly Gly Ser Gly 1 " 10 15
_.!"/ Gly Ala Tr.r Glu Lys Trp Glu Glu Thr Ser Leu Gly He A.rg Tr.r
Thr Me Leu A.rg Leu Ala Pr "al Gly Leu Cys Val Ala Ala
35 40 45 Leu Val Val Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He 50 55 60
Ser Tyr Ser A.sn Leu Thr A.la Phe Arg Tyr Leu Val His Ala Asn Gly 65 70 ' 5 80
He Cys Ala Gly Tyr Ser Leu Leu Ser Ala Ala He Ala Ala Met Pro 85 90 95
Arg Ser Ser Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp
100 105 110
Gin Leu Leu Thr Tyr Leu Val Leu Ala A.la Gly Ala Val Ser Ala Glu 115 120 125 Val Leu Tyr Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp 130 135 140
Ala Cys Ser Ser Tyr Gly Gly Fhe Cys His Arq Ala Thr Ala Ser Val 145 150 155 160
He He Thr Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He 165 170 175
Ser Ser Tyr Lys Leu Phe Thr A.rg Phe Asp Pro Pro Ser He Val Asp
180 185 190
Ser Ala Lys Asn Leu Glu Val Ala Val Phe Gly Ser 195 200 (2; INFORMATION FOR SEQ ID NO: 499: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 169 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..169 (D) OTHER INFORMATION: / Ceres Seq. ID 2053910
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 499: Met Leu Arg Leu Ala Pro Val Gly Leu Cys Val Ala Ala Leu Val Val 1 5 10 15
Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He Ser Tyr Ser 20 25 " 30
A.sn Leu Thr Ala Phe Arg Tyr Leu Val His Ala Asn Gly He Cys Ala 35 40 45 Gly Tyr Ser Leu Leu Ser Ala Ala He Ala Ala Met Pro Arg Ser Ser
50 55 60
Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp Gin Leu Leu 65 70 75 80 Thr Tyr Leu Val Leu Ala Ala Gly Ala Val Ser Ala Glu Val Leu Tyr
85 90 95
Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp Ala Cys Ser
100 105 110
Ser Tyr Gly Gly Phe Cys His Arg Ala Thr Ala Ser Val He He Thr 115 120 125
Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He Ser Ser Tyr
130 135 140
Lys Leu Phe Thr Arg Phe A.sp Pro Pro Ser He Val Asp Ser A.la Lys 145 150 155 160 Asn Leu Glu Val Ala Val Phe Gly Ser
165 (2) INFORMATION FOR SEQ ID NO:500: (i;> SEQUENCE CHARACTERISTICS: ι'A) LENGTH: 153 amino acids 'B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..153
(D) OTHER INFORMATION: / Ceres Seq. ID 2053911 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:500: Met Leu Lys Asp Ser Glu Thr Asn Glu Phe Gly Ser He Ser Tyr Ser 1 5 10 15
Asn Leu Thr Ala Phe Arg Tyr Leu Val His Ala Asn Gly He Cys Ala
20 ' 25 30
Gly Tyr Ser Leu Leu Ser A.la Ala He Ala Ala Met Pro Arg Ser Ser 35 40 45 Ser Thr Met Pro Arg Val Trp Thr Phe Phe Cys Leu Asp Gin Leu Leu 50 55 60
Thr Tyr Leu Val Leu Ala A.la Gly Ala Val Ser Ala Glu Val Leu Tyr 65 70 75 80
Leu Ala Tyr Asn Gly Asp Ser Ala He Thr Trp Ser Asp Ala Cys Ser 85 90 95
Ser Tyr Gly Gly Phe Cys His Arg Ala Thr Ala Ser Val He He Thr
100 105 110
Phe Phe Val Val Cys Phe Tyr He Val Leu Ser Leu He Ser Ser Tyr 115 120 125 Lys Leu Phe Thr Arg Phe Asp Pro Pro Ser He Val Asp Ser Ala Lys 130 135 140
Asn Leu Glu Val Ala Val Phe Gly Ser 145 150
(2) INFORMATION FOR SEQ ID NO: 501: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 652 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..652
(D) OTHER INFORMATION: / Ceres Seq. ID 2056123 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:501: attttttctt tctctctctc ctccctaagc aaaactaaaa caagctatgg ctggtatgct 60 tcccggagtt gagtgtgcaa ggaggcggcg cttccacggt ggtgctcctc cgattgaatc 120 ctcgaacaca gcttctgtgg cggctgcggc gggacacgtc tggacacggc gaccatcgtt 180 ctctctttac actaccaatc atgagagcca ccaggcccat gtctccttct cggagagaag 240 tgttaggaat aaatcttatg gagaagacaa cgatgagaaa cttgacggag cagccaaaga 300 ggcaaagcag aggcttaaca agcggctgag aatcccacca cgtacaaggc aaaatggtaa 360 agacaaaggg aataaattgg agcaaggaaa gggtaaacct ctcggggact taccgaccga 420 ggtggtcggg ttaaagaaga gccgaggaag gttgatggaa tggttcaagc ggcgagttag 480 ggaacaacaa gattgtgcta tatgtctaga ccggttcaag aagggtgaga ccttggtaca 540 cctaccatgt gcccataagt ttcactccat atgcttattg ccttggctag acaccaatgt 600 ttattgccca tattgtagaa ctgatatttg gaattaaatg ttatattttt ga (2) INFORMATION FOR SEQ ID NO: 502: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 196 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide
(ix) FEATURE: iA) NAME/KEY: peptide :B) LOCATION: 1..196
D) OTHER INFORMATION: : / Ceres Seq. IT : 205612*. i i) SEQUENCE DESCRIPTION: SEQ ID NO: 502:
Met A.la Gly Met Leu Pro Gly Val Glu Cys A.la A.rg Arg Arg Arg Phe
X 5 10 15
His Gly Gly Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala 20 25 30
Ala A.la Ala Gly His Val Trp Thr A.rg Arg Pro Ser Phe Ser Leu Tyr 35 40 45
Thr Thr Asn His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg
50 55 60 Ser Val Arg Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp 65 70 75 80
Gly Ala Ala Lys Glu Ala Lys Gin Arg Leu Asn Lys Arg Leu Arg He
85 90 95
Pro Pro Arg Thr Arg Gin Asn Gly Lys Asp Lys Gly Asn Lys Leu Glu 100 105 110
Gin Gly Lys Gly Lys Pro Leu Gly Asp Leu Pro Thr Glu Val Val Gly
115 120 125
Leu Lys Lys Ser Arg Gly A.rg Leu Met Glu Trp Phe Lys Arg A.rg Val
130 135 140 Arg Glu Gin Gin Asp Cys Ala He Cys Leu Asp Arg Phe Lys Lys Gly
145 150 155 ' 160
Glu Thr Leu Val His Leu Pro Cys Ala His Lys Phe His Ser He Cys
165 170 175
Leu Leu Pro Trp Leu Asp Thr Asn Val Tyr Cys Pro Tyr Cys Arg Thr 180 185 190
Asp He Trp Asn
195 (2) INFORMATION FOR SEQ ID NO: 503: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 193 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..193
(D) OTHER INFORMATION: / Ceres Seq. ID 2056125 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 503: Met Leu Pro Gly Val Glu Cys Ala Arg Arg Arg Arg Phe His Gly Gly 1 5 10 15
Ala Pro Pro He Glu Ser Ser Asn Thr Ala Ser Val Ala Ala Ala Ala 20 25 30
Gly His Val Trp Thr Arg Arg Pro Ser Phe Ser Leu Tyr Thr Thr Asn 35 40 45
His Glu Ser His Gin Ala His Val Ser Phe Ser Glu Arg Ser Val Arg 50 55 60
Asn Lys Ser Tyr Gly Glu Asp Asn Asp Glu Lys Leu Asp Gly Ala A.la
65 70 75 80
Lys Glu Ala Lys Gin Arg Leu Asn Lys A.rg Leu Arg He Pro Pro Arg 85 90 95
Thr Arg Gin Asn Gly Lys Asp Lys Gly Asn Lys Leu Glu Gin Gly Lys 100 105 110
Gly Lys Pro Leu Gly Asp Leu Pro Thr Glu Val Val Gly Leu Lys Lys 115 120 125
Ser Arg Gly Arg Leu Met Glu Trp Phe Lys Arg Arg Val Arg Glu Gin 130 135 140
Gin Asp Cys Ala He Cys Leu A.sp A.rg Phe Lys Lys Gly Glu Thr Leu
145 150 155 160
Val His Leu Pro Cys A.la His Lys Phe His Ser He Cys Leu Leu Pro 165 170 175
_ rF Leu Asp Thr Asn . al Tyr Cys Pro Tyr C/s A.rg Thr Asp He Trp 180 185 190
( 2 ) INFORMAT ION FOR SEQ I D NO : 504
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 2619 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: DNA (genomic)
( x) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..2619 (D) OTHER INFORMATION: / Ceres Seq . ID 2056245 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 504 atggagcaag agaaaagctt ggatccacaa ctatggcatg cttgtgcagg atcaatggtt 60 caaatccctt cactgaattc aacggttttt tacttcgctc aaggecacac agagcacgct 120 cacgcgcctc ctgattttca cgcgccgcgc gttccacctc ttatcctctg tcgtgtcgtc 180 tccgtgaagt tcctcgccga cgctgaaaca gacgaagttt ttgctaaaat tacgcttttg 240 ccacttccgg gaaacgactt ggatctagaa aacgacgccg ttttgggtct aactcctcct 300 tcttctgacg gtaacggtaa cggtaaagag aaaccggcgt ctttcgctaa aacgttaacg 360 cagtctgacg ctaataacgg cggtggtttc tccgttccac gttattgcgc cgagacgatt 420 ttcccgcggc ttgattactc ggcggagcca ccggttcaaa ccgtgattgc taaagacatc 480 cacggcgaga cttggaaatt ccggcatatt tacagaggaa cacctcgccg tcatctccta 540 accaccggtt ggagcacttt cgttaaccag aagaaactaa tcgccggaga ctcaatcgtc 600 ttcctccgtt ctgaatccgg tgacctctgc gtcggaatcc gccgcgctaa acgcggcggt 660 ctcggatcta acgcaggatc cgacaatcct taccctggat tctccggttt cctccgtgac 720 gacgagtcaa caacaacaac atcgaagcta atgatgatga aacgcaacgg aaacaacgac 780 ggaaacgccg cggctacagg gagggttaga gtagaagcag tagcggaagc ggtggcgcgt 840 gcagcgtgtg gacaagcgtt tgaggttgtt tattatccac gcgctagtac accggagttt 900 tgcgtaaaag cagctgatgt tagatcagca atgaggataa gatggtgtag tggtatgcgt 960 tttaaaatgg cgtttgaaac agaggattct tctagaatca gttggtttat gggtactgtc 1020 tccgccgttc aagtcgctga tccaattcgt tggcctaatt caccatggcg tctccttcag 1080 gtagcttggg acgaaccgga tttgttacaa aacgttaagc gggttagtcc gtggttagtc 1140 gaattggtat cgaacatgcc tacaatacat ttatctccat tctctccgag gaagaagatt 1200 aggattccgc agccatttga gtttccattc cacggtacta aattcccgat tttctccccg 1260 ggattcgcca acaatggcgg tggcgagtcc atgtgttatc tgtcaaacga caacaataat 1320 gctcctgcag gaatacaggg agccaggcaa gctcaacaac tcttcggatc accatctccg 1380 tctttgttgt ctgatctcaa tcttagtagt tacaccggta acaacaagtt acattctccg 1440 gcgatgtttc tatcgagttt caacccgagg catcatcatt atcaggctag ggatagtgag 1500 aatagtaata acatttcgtg ttctttaact atggggaatc ctgctatggt tcaggataag 1560 aagaagtctg ttggttcggt taagactcat cagttcgtgt tgttcggtca accgatttta 1620 accgaacagc aagttatgaa ccgaaaacgg tttttggaag aagaggcgga agcggaggag 1680 gagaaaggtt tagtggctcg tgggttaaca tggaattata gtttgcaagg acttgagacg 1740 ggtcattgta aagttttcat ggaatctgag gatgttggac gcacactcga tctctcggtt 1800 attggctcgt accaagaatt gtaccggaaa ttggctgaga tgtttcatat agaagagagg 1860 tcggatttgt tgactcatgt tgtgtaccgg gatgcaaatg gtgttatcaa acgtattgga 1920 gacgaacctt tcagtgattt catgaaagca actaaacggc taacaatcaa gatggatatt 1980 ggtggcgaca acgtgagaaa catttttagt ttccttcaaa taatattttt tttctttttt 2040 ttcaaaaaat taattttttt tttgttcttt tccgatggtg gatactatac tcatatacat 2100 atatattcat cagattatat atatatatat atatatatat atataagtaa tataaaaaaa 2160 aaaettattt tgttcattct tttaagttta aaaacagtca attcatttat atcatctatg 2220 atgaagaaac tcattcaact ctcgttcact gttatgatta tcttcaccat tcttgtgcta 2280 ggagtggtgg caaatgaggg getaggaaaa ccaaaaaaac aatgtaatga gattctaaag 2340 caatccaact gtgttgctgc agagtgtgac tctatgtgtg tgaagaagag ggggaaagga 2400 gccggttact gctctccttc taaaaagtgt tactgctatt atcattgccc ttaacgattt 2460 tattatttac aataataaga gatttatgat aaagtagtaa aataatgaat cgggtgttta 2520 tagcctaacg attgatatag ttgtctctat caaataaact atatagacta aaagtaataa 2580 taataatgac aatcataact cagaagtttt tgtttagtc (2) INFORMATION FOR SEQ ID NO: 505: 'i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 817 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide viχ) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..817
(D) OTHER INFORMATION: / Ceres Seq. ID 2056246 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:505: Met Glu Gin Glu Lys Ser Leu Asp Pro Gin Leu Trp His Ala Cys Ala 1 5 10 15
Gly Ser Met Val Gin He Pro Ser Leu Asn Ser Thr Val Phe Tyr Phe
20 25 30
Ala Gin Gly His Thr Glu His Ala His Ala Pro Pro Asp Phe His Ala 35 40 45
Pro A.rg Val Pro Pro Leu He Leu Cys Arg Val Val Ser Val Lys Phe
50 55 60
Leu Ala Asp Ala Glu Thr Asp Glu Val Phe Ala Lys He Thr Leu Leu 65 70 75 80 Pro Leu Pro Gly Asn Asp Leu Asp Leu Glu Asn Asp Ala Val Leu Gly
85 90 95
Leu Thr Pro Pro Ser Ser A.sp Gly Asn Gly Asn Gly Lys Glu Lys Pro
100 105 110
Ala Ser Phe Ala Lys Thr Leu Thr Gin Ser Asp Ala Asn Asn Gly Gly 115 " 120 125
Gly Phe Ser Val Pro Arg Tyr Cys Ala Glu Thr He Phe Pro Arg Leu
130 135 140
Asp Tyr Ser Ala Glu Pro Pro Val Gin Thr Val He Ala Lys Asp He 145 150 155 160 His Gly Glu Thr Trp Lys Phe Arg His He Tyr Arg Gly Thr Pro Arg
165 170 175
Arg His Leu Leu Thr Thr Gly Trp Ser Thr Phe Val Asn Gin Lys Lys
180 185 190
Leu He Ala Gly Asp Ser He Val Phe Leu Arg Ser Glu Ser Gly Asp 195 200 205
Leu Cys Val Gly He Arg Arg Ala Lys Arg Gly Gly Leu Gly Ser Asn
210 215 220
Ala Gly Ser Asp Asn Pro Tyr Pro Gly Phe Ser Gly Phe Leu A.rg Asp 225 230 235 240 Asp Glu Ser Thr Thr Thr Thr Ser Lys Leu Met Met Met Lys A.rg Asn
245 250 255
Gly Asn Asn Asp Gly Asn Ala Ala Ala Thr Gly Arg Val Arg Val Glu 260 265 270
Ala Val Ala Glu Ala Val Ala Arg Ala Ala Cys Gly Gin Ala Phe Glu
275 280 285
Val Val Tyr Tyr Pro Arg Ala Ser Thr Pro Glu Phe Cys Val Lys Ala 290 295 300
Ala Asp Val Arg Ser Ala Met Arg He Arg Trp Cys Ser Gly Met Arg
305 310 315 320
Phe Lys Met Ala Phe Glu Thr Glu Asp Ser Ser Arg He Ser Trp Phe
325 330 335 Met Gly Thr Val Ser Ala Val Gin Val Ala Asp Pro He Arg Trp Pro
340 345 350
A.sn Ser Pro Trp A.rg Leu Leu Gin Val Ala Trp A.sp Glu Pro Asp Leu
355 360 365
Leu Gin Asn Val Lys Arg Val Ser Pro Trp Leu Val Glu Leu Val Ser 370 375 380
A.sn Met Pro Thr He His Leu Ser Pro Phe Ser Pro Arg Lys Lys He
385 390 395 400
A.rg He Pro Gin Pro Phe Glu Phe Pro Phe His Gly Thr Lys Phe Pro
405 410 415 He Phe Ser Pro Gly Phe Ala Asn Asn Gly Gly Gly Glu Ser Met Cys
420 425 430
Tyr Leu Ser A.sn Asp Asn A.sn A.sn Ala Pro Ala Gly He Gin Gly A.la
435 440 445
Arg Gin A.la Gin Gin Leu Phe Gly Ser Pro Ser Pro Ser Leu Leu Ser 450 455 " 460
A.sp Leu Asn Leu Ser Ser Tyr Thr Gly Asn Asn Lys Leu His Ser Pro
465 470 475 * 480
Ala Met Phe Leu Ser Ser Phe Asn Pro Arg His His His Tyr Gin Ala
485 490 495 Arg Asp Ser Glu Asn Ser Asn Asn He Ser Cys Ser Leu Thr Met Gly
500 505 510
Asn Pro Ala Met Val Gin Asp Lys Lys Lys Ser Val Gly Ser Val Lys
515 520 525
Thr His Gin Phe Val Leu Phe Gly Gin Pro He Leu Thr Glu Gin Gin 530 535 540
Val Met Asn Arg Lys Arg Phe Leu Glu Glu Glu Ala Glu Ala Glu Glu
545 550 555 560
Glu Lys Gly Leu Val Ala Arg Gly Leu Thr Trp Asn Tyr Ser Leu Gin
565 570 575 Gly Leu Glu Thr Gly His Cys Lys Val Phe Met Glu Ser Glu Asp Val
580 585 590
Gly Arg Thr Leu Asp Leu Ser Val He Gly Ser Tyr Gin Glu Leu Tyr
595 600 605
Arg Lys Leu Ala Glu Met Phe His He Glu Glu Arg Ser Asp Leu Leu 610 615 620
Thr His Val Val Tyr Arg Asp Ala Asn Gly Val He Lys Arg He Gly
625 630 635 640
Asp Glu Pro Phe Ser Asp Phe Met Lys Ala Thr Lys Arg Leu Thr He
645 650 655 Lys Met Asp He Gly Gly Asp Asn Val Arg Asn He Phe Ser Phe Leu
660 665 670
Gin He He Phe Phe Phe Phe Phe Phe Lys Lys Leu He Phe Phe Leu
675 680 685
Phe Phe Ser Asp Gly Gly Tyr Tyr Thr His He His He Tyr Ser Ser 690 695 700
Asp Tyr He Tyr He Tyr He Tyr He Tyr He Ser Asn He Lys Lys
705 710 715 720
Lys Leu He Leu Phe He Leu Leu Ser Leu Lys Thr Val Asn Ser Phe
725 730 735 He Ser Ser Met Met Lys Lys Leu He Gin Leu Ser Phe Thr Val Met
740 745 750
He He Phe Thr He Leu Val Leu Gly Val Val Ala Asn Glu Gly Leu 755 760 765
Gly Lys Pro Lys Lys Gin Cys Asn Glu He Leu Lys Gin Ser Asn Cys
770 775 780
Val Ala Ala Glu Cys Asp Ser Met Cys Val Lys Lys Arg Gly Lys Gly 785 790 795 800
Ala Gly Tyr Cys Ser Pro Ser Lys Lys Cys Tyr Cys Tyr Tyr His Cys
805 810 815
Pro (2) INFORMATION FOR SEQ ID NO: 506: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 799 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..799 ,D) OTHER INFORMATION: ' Ceres Seq. ID 2056247
•xi; SEQUENCE DESCRIPTION: SEQ ID NO: 506: Met Val Gin He Pro Ser Leu Asn Ser Thr Val Phe Tyr Phe Ala Gin 1 5 10 " 15
Gly His Thr Glu His Ala His Ala Pro Pro Asp Phe His A.la Pro Arg " 20 25 30
Val Pro Pro Leu He Leu Cys Arg Val Val Ser Val Lys Phe Leu Ala
35 40 45
A.sp Ala Glu Thr Asp Glu Val Phe Ala Lys He Thr Leu Leu Pro Leu 50 55 60 Pro Gly Asn Asp Leu Asp Leu Glu Asn Asp Ala Val Leu Gly Leu Thr 65 70 75 80
Pro Pro Ser Ser Asp Gly Asn Gly Asn Gly Lys Glu Lys Pro Ala Ser
85 " 90 95
Phe Ala Lys Thr Leu Thr Gin Ser Asp Ala Asn Asn Gly Gly Gly Phe 100 105 110
Ser Val Pro Arg Tyr Cys A.la Glu Thr He Phe Pro Arg Leu Asp Tyr
115 120 125
Ser Ala Glu Pro Pro Val Gin Thr Val He Ala Lys Asp He His Gly
130 135 140 Glu Thr Trp Lys Phe Arg His He Tyr Arg Gly Thr Pro Arg Arg His
145 150 155 160
Leu Leu Thr Thr Gly Trp Ser Thr Phe Val Asn Gin Lys Lys Leu He
165 170 175
Ala Gly Asp Ser He Val Phe Leu Arg Ser Glu Ser Gly Asp Leu Cys 180 185 190
Val Gly He Arg Arg Ala Lys Arg Gly Gly Leu Gly Ser Asn Ala Gly
195 200 205
Ser Asp Asn Pro Tyr Pro Gly Phe Ser Gly Phe Leu A.rg Asp Asp Glu
210 215 220 Ser Thr Thr Thr Thr Ser Lys Leu Met Met Met Lys Arg Asn Gly Asn
225 230 235 240
Asn Asp Gly Asn Ala Ala Ala Thr Gly Arg Val Arg Val Glu Ala Val
245 250 255
Ala Glu Ala Val Ala Arg Ala Ala Cys Gly Gin Ala Phe Glu Val Val 260 265 270
Tyr Tyr Pro Arg Ala Ser Thr Pro Glu Phe Cys Val Lys Ala Ala Asp
275 280 285
Val Arg Ser Ala Met Arg He Arg Trp Cys Ser Gly Met Arg Phe Lys
290 295 300 Met Ala Phe Glu Thr Glu Asp Ser Ser Arg He Ser Trp Phe Met Gly
305 310 315 320
Thr Val Ser Ala Val Gin Val Ala Asp Pro He Arg Trp Pro Asn Ser 325 330 335
Pro Trp Arg Leu Leu Gin Val Ala Trp Asp Glu Pro Asp Leu Leu Gin
340 345 350
Asn Val Lys Arg Val Ser Pro Trp Leu Val Glu Leu Val Ser Asn Met 355 360 365
Pro Thr He His Leu Ser Pro Phe Ser Pro Arg Lys Lys He Arg He
370 375 380
Pro Gin Pro Phe Glu Phe Pro Phe His Gly Thr Lys Phe Pro He Phe 385 390 395 400 Ser Pro Gly Phe Ala Asn Asn Gly Gly Gly Glu Ser Met Cys Tyr Leu
405 410 415
Ser Asn Asp A.sn Asn Asn Ala Pro Ala Gly He Gin Gly Ala A.rg Gin
420 425 430
Ala Gin Gin Leu Phe Gly Ser Pro Ser Pro Ser Leu Leu Ser Asp Leu 435 440 445
Asn Leu Ser Ser Tyr Thr Gly A.sn Asn Lys Leu His Ser Pro Ala Met
450 455 460
Phe Leu Ser Ser Phe A.sn Pro Arg His His His Tyr Gin Ala Arg Asp 465 470 475 480 Ser Glu A.sn Ser Asn A.sn He Ser Cys Ser Leu Thr Met Gly Asn Pro
485 490 495
Ala Met Val Glr. Asp Lys Lys Lys Ser Val Gly Ser Val Lys Thr His
500 505 510
Gin Phe Val Leu Phe Gly Gin Pro He Leu Thr Glu Gin Gin Val Met 515 520 525
Asn A.rg Lys Arg Phe Leu Glu Glu Glu Ala Glu A.la Glu Glu Glu Lys
530 535 540
Gly Leu Val A.la Arg Gly Leu Thr Trp Asn Tyr Ser Leu Gin Gly Leu 545 550 555 560 Glu Thr Gly His Cys Lys Val Phe Met Glu Ser Glu Asp Val Gly Arg
565 570 575
Thr Leu Asp Leu Ser Val He Gly Ser Tyr Gin Glu Leu Tyr Arg Lys
580 585 590
Leu Ala Glu Met Phe His He Glu Glu Arg Ser Asp Leu Leu Thr His 595 600 605
Val Val Tyr Arg Asp A.la Asn Gly Val He Lys Arg He Gly A.sp Glu
610 615 620
Pro Phe Ser A.sp Phe Met Lys A.la Thr Lys A.rg Leu Thr He Lys Met 625 630 " 635 640 Asp He Gly Gly Asp Asn Val Arg Asn He Phe Ser Phe Leu Gin He
645 650 655
He Phe Phe Phe Phe Phe Phe Lys Lys Leu He Phe Phe Leu Phe Phe
660 665 670
Ser Asp Gly Gly Tyr Tyr Thr His He His He Tyr Ser Ser Asp Tyr 675 680 685
He Tyr He Tyr He Tyr He Tyr He Ser Asn He Lys Lys Lys Leu
690 695 700
He Leu Phe He Leu Leu Ser Leu Lys Thr Val Asn Ser Phe He Ser 705 710 715 720 Ser Met Met Lys Lys Leu He Gin Leu Ser Phe Thr Val Met He He
725 730 735
Phe Thr He Leu Val Leu Gly Val Val Ala Asn Glu Gly Leu Gly Lys
740 745 750
Pro Lys Lys Gin Cys Asn Glu He Leu Lys Gin Ser Asn Cys Val Ala 755 760 765
Ala Glu Cys Asp Ser Met Cys Val Lys Lys Arg Gly Lys Gly Ala Gly
770 775 780
Tyr Cys Ser Pro Ser Lys Lys Cys Tyr Cys Tyr Tyr His Cys Pro 785 790 795 (2) INFORMATION FOR SEQ ID NO: 507: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 567 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..567
(D) OTHER INFORMATION: / Ceres Seq. ID 2056248 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 507: Met Met Met Lys Arg Asn Gly Asn Asn Asp Gly Asn A.la A.la A.la Thr 1 ^ 5 10 15
Gly A.rg Val Arg Val Glu A.la Val A.la Glu Ala Val A.la A.rg A.la A.la
20 25 30
Cys Gly Gin Ala Phe Glu Val Val Tyr Tyr Pro Arg Ala Ser Thr Pro 35 40 45
Glu Pne Cys Val Lys Ala Ala A.sp Val A.rg Ser A.la Met Arg He Arg
50 55 60
Trp Cys Ser Gly Met A.rg Phe Lys Met Ala Phe Glu Thr Glu Asp Ser 65 70 75 80 Ser Arq He Ser Trp Phe Met Gly Thr "'al Ser Ala Val Gin "al Ala
85 5 95
A.sp Pro He A.rg Trp Pro A.sn Ser Pre Trp A.rg Leu Leu Gin "al A.la
100 105 110
Trp Asp Glu Pro Asp Leu Leu Gin Asn Val Lys A.rg Val Ser Pro Trp 115 120 " 125
Leu Val Glu Leu Val Ser A.sn Met Fro Thr He His Leu Ser Pro Phe
130 135 140
Ser Pro A.rg Lys Lys He A.rg He Pro Gin Pro Phe Glu Phe Pro Phe 145 150 155 160 His Gly Thr Lys Phe Pro He Phe Ser Pro Gly Phe A.la Asn A.sn Gly
165 170 175
Gly Gly Glu Ser Met Cys Tyr Leu Ser A.sn A.sp A.sn A.sn Asn A.la Pro
180 185 190
Ala Gly He Gin Gly Ala Arg Gin Ala Gin Gin Leu Phe Gly Ser Pro 195 200 205
Ser Pro Ser Leu Leu Ser Asp Leu Asn Leu Ser Ser Tyr Thr Gly A.sn
210 215 220
A.sn Lys Leu His Ser Pro A.la Met Phe Leu Ser Ser Phe A.sn Pro Arg 225 230 235 240 His His His Tyr Gin Ala A.rg Asp Ser Glu Asn Ser Asn Asn He Ser
245 250 255
Cys Ser Leu Thr Met Gly A.sn Pro Ala Met Val Gin Asp Lys Lys Lys
260 265 270
Ser Val Gly Ser Val Lys Thr His Gin Phe Val Leu Phe Gly Gin Pro 275 280 285
He Leu Thr Glu Gin Gin Val Met Asn Arg Lys A.rg Phe Leu Glu Glu
290 295 300
Glu Ala Glu Ala Glu Glu Glu Lys Gly Leu Val A.la Arg Gly Leu Thr 305 310 315 320 Trp Asn Tyr Ser Leu Gin Gly Leu Glu Thr Gly His Cys Lys Val Phe
325 330 " 335
Met Glu Ser Glu Asp Val Gly Arg Thr Leu Asp Leu Ser Val He Gly
340 345 350
Ser Tyr Gin Glu Leu Tyr Arg Lys Leu Ala Glu Met Phe His He Glu 355 360 365
Glu Arg Ser Asp Leu Leu Thr His Val Val Tyr Arg Asp Ala Asn Gly
370 375 380
Val He Lys Arg He Gly A.sp Glu Pro Phe Ser Asp Phe Met Lys Ala 385 390 395 400 Thr Lys Arg Leu Thr He Lys Met Asp He Gly Gly Asp Asn Val Arg
405 410 415
Asn He Phe Ser Phe Leu Gin He He Phe Phe Phe Phe Phe Phe Lys 420 425 430
Lys Leu He Phe Phe Leu Phe Phe Ser Asp Gly Gly Tyr Tyr Thr His
435 440 445
He His He Tyr Ser Ser Asp Tyr He Tyr He Tyr He Tyr He Tyr 450 455 4 60
He Ser Asn He Lys Lys Lys Leu He Leu Phe He Leu Leu Ser Leu
465 470 475 480
Lys Thr Val A.sn Ser Phe He Ser Ser Met Met Lys Lys Leu He Gin
485 490 495 Leu Ser Phe Thr Val Met He He Phe Thr He Leu Val Leu Gly Val
500 505 510
Val Ala A.sn Glu Gly Leu Gly Lys Pro Lys Lys Gin Cys Asn Glu He
515 520 525
Leu Lys Gin Ser Asn Cys Val Ala Ala Glu Cys Asp Ser Met Cys Val 530 535 540
Lys Lys A.rg Gly Lys Gly A.la Gly Tyr Cys Ser Pro Ser Lys Lys Cys 545 550 555 560
Tyr Cys Tyr Tyr His Cys Pro 565 2, INFORMATION FOR SEQ ID MO: 508: !i) SEQUENCE CHARACTERISTICS:
■'A; LENGTH: 776 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA. (genomic; (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..776 (D) OTHER INFORMATION: / Ceres Seq. ID 1941142
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 508: agtcgcctcc ttcctgcgcc gccgccgccg ccgccgccgc cgctaccacc gcctcgcggc 60 cgcctgcggc tccgcgtttc cgcacggaag ttggtgaagg tttcttgagg ctgagaacat 120 ggtgctgaag acggaacttt gccgcttcag cggccagaag atttatcctg ggaaaggcat 180 tagatttatc cgtgctgatt ctcaggtctt cctttttgcc aactcgaaat gcaagcgcta 240 cttccacaac cgcctgaagc ctgcaaagct tacctggaca gcaatgtaca ggaagcagca 300 caagaaggat atccatgctg aagcggtaaa gaagaggcgc cgcgccacca agaagccata 360 ctccaggtca attgtgggtg cttccttgga agtaatccag aagaagagag ctgagaagcc 420 agaggtccgc gatgctgcta gagaggctgc tcttcgtgag atcaaggagc gcatcaagaa 480 gaccaaggat gagaagaaag cgaagaaggc ggaggtgagc aagtcccaga agacgcagac 540 aaagggtgcg gtccagaagg gttccaaggg ccccaagttg ggcggcggtg gtgggaagcg 600 ctgaaagaac ttagtgtcgt ttctcgacat tgcagtcgtt ccttagccaa agccactttc 660 gtagaacctg tgttgaattt gcaagactta ttcaagcgtt gettgtgcgt getaaatacc 720 atggcaagag aacggattta tatttatgcc tgaaaaaaat gaccgttcat attctt (2) INFORMATION FOR SEQ ID NO: 509:' (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 161 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..161 (D) OTHER INFORMATION: / Ceres Seq. ID 1941143
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 509: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 15
Pro Gly Lys Gly He Arg Phe He Arg Ala Asp Ser Gin Val Phe Leu 20 25" 30
Phe Ala Asn Ser Lys Cys Lys Arg Tyr Phe His Asn Arg Leu Lys Pro 35 40 45 Ala Lys Leu Thr Trp Thr Ala Met Tyr Arg Lys Gin His Lys Lys Asp
50 55 60
He His Ala Glu Ala Val Lys Lys Arg Arg Arg Ala Thr Lys Lys Pro 65 70 75 80 Tyr Ser Arg Ser He Val Gly Ala Ser Leu Glu Val He Gin Lys Lys
85 90 95
Arg A.la Glu Lys Pro Glu Val Arg Asp Ala Ala Arg Glu A.la Ala Leu
100 105 110
Arg Glu He Lys Glu Arg He Lys Lys Thr Lys Asp Glu Lys Lys Ala ' 115 120 125
Lys Lys A.la Glu Val Ser Lys Ser Gin Lys Thr Gin Thr Lys Gly Ala
130 135 140
Val Gin Lys Gly Ser Lys Gly Pro Lys Leu Gly Gly Gly Gly Gly Lys 145 150 155 160 Arg
(2) INFORMATION FOR SEQ ID NO:510: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 106 amino acids (B) TYPE: ammo acid
C) STRANDEDNESS:
D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..106
(D) OTHER INFORMATION: / Ceres Seq. ID 1941144 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:510: Met Tyr Arg Lys Gin His Lys Lys Asp He His Ala Glu Ala Val Lys 1 5 10 15
Lys A.rg Arg Arg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly
20 25 30
Ala Ser Leu Glu Val He Gin Lys Lys A.rg A.la Glu Lys Pro Glu Val 35 40 45 Arg Asp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu Arg He 50 55 60
Lys Lys Thr Lys A.sp Glu Lys Lys Ala Lys Lys Ala Glu Val Ser Lys 65 70 "5 80
Ser Gin Lys Thr Gin Thr Lys Gly Ala Val Gin Lys Gly Ser Lys Gly 85 90 ' 95
Pro Lys Leu Gly Gly Gly Gly Gly Lys Arg
100 105
(2) INFORMATION FOR SEQ ID NO: 511: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1024 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1024
(D) OTHER INFORMATION: / Ceres Seq. ID 1942975 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 511: ataaattcct ccgctcccct tcgccgcttc ctgtcgcgcc gccgctcccc tcccaaccca 60 ctagctcaaa accctagagc tctcgcctgc tcgcctccgc cgccggagcg agctccccat 120 cttcatccgt caaccatggc gacccagatc agcaagaaga agaagttcgt cagcgacggt 180 gttttctacg ccgagctcaa tgagatgctg acgcgggagc tggcggagga cggctactct 240 ggcgtggagg tgcgcgtcac gccgatgcgc acggagatca tcatccgcgc cacgcgcacg 300 eagaacgtgc tcggcgagaa gggccgtagg atcagggagc tcacctccgt cgtccagaag 360 aggttcaact tccctgagaa tggcgttgag ctttatgccg agaaggtcgt caaccgtggg 420 ctctgtgcca tcgcgcaggc cgagtccctc cgttacaagc tcctcggtgg ccttgccgtc 480 cgcagggctt gctacggtgt tcttcgttat gttatggaga gtggtgccaa gggttgtgag 540 gtgatcgtga gtggaaagct cagggcccaa agagccaagt ccatgaagtt caaggatggc 600 tacatgatct catctggtca accagtgaac gagtacattg actcggctgt gagacacgtt 660 cttctcagac agggtgttct tggcatcaag gtgaagatca tgcttgactg ggacccgaag 720 ggcaaggttg gcccgatcac tcctcttccg gacctggtga ccatccacac cccgaaggac 780 gaggacgagc cgcgccctcc ggtcttggca cctcctgagg tgtaaggtcc caactgtgtc 840 cttgaaatgg cagtttgatc gggtcctaga taggtttcta tcttacgata aggacaatgc 900 taaggcagtt ggttacctta atctttatgg acagatgcta tgtgttgctt ctgtggcact 960 tttgtttaag ctaagttttg cggagacaag atacttatat atgttcccga tgaaattatg 1020 gttc
(2) INFORMATION FOR SEQ ID NO:512: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 274 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide άx) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..274
I C ) OTHER INFORMATION: / Ceres Seq. ID 1942976
(xi) SEQUENCE DESCRIPTION: SEQ IC NO: 512: lie A.sn Ser Ser A.l≤ Pro Leu Arg A.rg Phe Leu _er arg Arg Arg
1 10 15
Pro Pro Asn Pro Leu Ala Gin Asn Pro Arq Ala Leu A.la Cys Ser Pr
20 30
Pro Pro Pro Glu Arg Ala Pro His Leu His Pro Ser Thr Met A.la Thr
35 40 45
Gin He Ser Lys Lys Lys Lys Phe Val Ser Asp Gly Val Phe Tyr Ala
50 55 6θ'
Glu Leu Asn Glu Met Leu Thr Arg Glu Leu Ala Glu Asp Gly Tyr Ser 65 70 75 80
Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He He He Arg
85 90 95
Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg Arg He Arg
100 105 110 Glu Leu Thr Ser Val Val GI Lys Arg Phe A.sn Phe Pro Glu A.sn Gly 115 120 125
Val Glu Leu Tyr Ala Glu Lys Val Val Asn A.rg Gly Leu Cys Ala He
130 135 140
Ala Gin Ala Glu Ser Leu A.rg Tyr Lys Leu Leu Gly Gly Leu A.la Val
145 150 155 160
Arg Arg Ala Cys Tyr Gly Val Leu Arg Tyr Val Met Glu Ser Gly Ala 165 170 175
Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala Gin Arg Ala 180 185 190
Lys Ser Met Lys Phe Lys Asp Gly Tyr Met He Ser Ser Gly Gin Pro 195 200 205
Val Asn Glu Tyr He Asp Ser Ala Val Arg His Val Leu Leu Arg Gin 210 215 220
Gly Val Leu Gly He Lys Val Lys He Met Leu Asp Trp Asp Pro Lys
225 230 235 240
Gly Lys Val Gly Pro He Thr Pro Leu Pro Asp Leu Val Thr He His 245 250 255
Thr Pro Lys Asp Glu Asp Glu Pro Arg Pro Pro Val Leu Ala Pro Pro 260 265 270
Glu Val
(2) INFORMATION FOR SEQ ID NO: 513: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 229 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..229
(D) OTHER INFORMATION: / Ceres Seq. ID 1942977 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:513: Met Ala Thr Gin He Ser Lys Lys Lys Lys Phe Val Ser Asp Gly Val 1 5 10 15
Phe Tyr Ala Glu Leu Asn Glu Met Leu Thr Arg Glu Leu Ala Glu Asp
20 25 30
Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He 35 40 45 He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg Ξ! 55 60
Arg He Arg Glu Leu Thr Ser Val Val Gin Lys A.rg Phe A.sn Phe Pro 65 70 75 80
Glu Asn Gly Val Glu Leu Tyr Ala Glu Lys Val Val Asn A.rg Gly Leu 65 90 95
Cys A a He Ala Gin A.la Glu Ser Leu A.rg Tyr Lys Leu Leu Gly Gly
100 105 " 110
Leu A a Val A.rg Arg A a Cys Tyr Gly Val Leu A.rg Tyr Val Met Glu 115 120 125 Ser Gly Ala Lys Gly Cys Glu Val He Val Ser Gly Lys Leu Arg A.la 120 135 140
Gin A.rg A.la Lys Ser Met Lys Phe Lys Asp Gly Tyr Met He Ser Ser 145 150 * " 155 " 160
Gly Gin Pro Val A.sn Glu Tyr He Asp Ser Ala Val Arg His Val Leu 165 " 170 " 175
Leu A.rg Gin Gly Val Leu Gly He Lys Val Lys He Met Leu Asp Trp
180 185 190
Asp Pro Lys Gly Lys Val Gly Pro He Thr Pro Leu Pro Asp Leu Val 195 200 205 Thr He His Thr Pro Lys Asp Glu Asp Glu Pro Arg Pro Pro Val Leu 210 215 220
A.la Pro Pro Glu Val 225
.2) INFORMATION FOR SEQ ID NO: 514: ' 'i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 206 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..206
(D) OTHER INFORMATION: / Ceres Seq. ID 1942978 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 514:
Met Leu Thr Arg Glu Leu Ala Glu Asp Gly Tyr Ser Gly Val Glu Val 1 5 10 15
Arg Val Thr Pro Met Arg Thr Glu He He He A.rg Ala Thr Arg Thr 20 25 30 Gin A.sn Val Leu Gly Glu Lys Gly Arg Arg He Arg Glu Leu Thr Ser 35 40 45
Val Val Gin Lys Arg Phe Asn Phe Pro Glu A.sn Gly Val Glu Leu Tyr
50 55 60
Ala Glu Lys Val Val Asn Arg Gly Leu Cys Ala He Ala Gin Ala Glu 65 70 75 80
Ser Leu Arg Tyr Lys Leu Leu Gly Gly Leu Ala Val Arg Arg Ala Cys 85 90 95 Tyr Gly Val Leu Arg Tyr Val Met Glu Ser Gly Ala Lys Gly Cys Glu
100 105 110
Val He Val Ser Gly Lys Leu Arg Ala Gin Arg Ala Lys Ser Met Lys 115 120 125 Phe Lys Asp Gly Tyr Met He Ser Ser Gly Gin Pro Val Asn Glu Tyr 130 135 140
He Asp Ser Ala Val Arg His Val Leu Leu Arg Gin Gly Val Leu Gly 145 150 155 160
He Lys Val Lys He Met Leu Asp Trp Asp Pro Lys Gly Lys Val Gly "" 165 170 175
Pro He Thr Pro Leu Pro Asp Leu Val Thr He His Thr Pro Lys Asp
180 185 190
Glu A.sp Glu Pro A.rg Pro Pro Val Leu Ala Pro Pro Glu Val 195 200 205 (2) INFORMATION FOR SEQ ID NO:515: 'i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1069 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single ( i TOPOLOGY: linear
. ' MOLECULE TYPE: DNA (genomic) x; FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1069 (D) OTHER INFORMATION: / Ceres Seq. ID 1944349
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:515: acttcgtttc tgcctttgac cagctcttgc gctcggctta tctcgtgcgg ttgttgctag 60 aaccgtccct aattccattc ccgtgatctg gtttagtcat ttcatggttt tatttgttgc 120 atctgtggtg aatctgtggt cacttagatc aacataggaa gatgtacgcc cagttgagtt 180 ttgagtcggc tgttggtgtt tccctaacta gggactgagg gtctgaagct ctatacctgt 240 tgcaatcgcg tagttgtgcg tgctagatgt atcagagaat ccctttgagt agaaagcaca 300 cgcacacagc tgccacggta ttggcattcg taggtatctg tttcactgac gtgctacctg 360 cacgaggata gcacctgata tttgtgcgct ttttttggtg aagatttttt gaagctgaga 420 agatggtgct gaagacggaa ctctgecgct tcagtggcca gaagatctat cctgggaaag 480 gcatccggtt tattcgtgct gattctcagg ttttcctttt tgccaactct aaatgcaagc 540 gctacttcca caaccgcctg aagcctgcaa agcttacctg gacagcaatg tacaggaagc 600 agcacaagaa ggacatccat gctgaagctg tcaagaagag gcgccgcgcc accaagaagc 660 catactcgag gtccattgtg ggtgcttcct tggaagtgat ccagaagaag agagctgaga 720 agcctgaggt ccgtgatgct gctagagaag ctgctcttcg tgagatcaag gagcgcatca 780 agaagaccaa ggacgagaag aaggcgaaga aggctgaggt gtccaagtcc cagaaggcgc 840 agacgaaggg cgctgtccag aagggttcca agggccccaa gttgggcggc ggcggtggca 900 aacgctgaaa aggaacgaag tgtcatttcg agacctcacc aaagtcacct ttgtagtacc 960 tgggttaatt ttgcatttte gttcagagtt acttgtgact cttaactaec atgtcaagag 1020 aatggattcg ttatttttat atattgggag aaatgatcgc cgttccttc (2) INFORMATION FOR SEQ ID NO: 516: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 161 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..161 (D) OTHER INFORMATION: / Ceres Seq. ID 1944350
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:516: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 15
Pro Gly Lys Gly He Arg Phe He Arg Ala Asp Ser Gin Val Phe Leu 20 25 30
Phe Ala Asn Ser Lys Cys Lys Arg Tyr Phe His Asn Arg Leu Lys Pro 35 40 45 Ala Lys Leu Thr Trp Thr Ala Met Tyr Arg Lys Gin His Lys Lys Asp
50 55 60
He His Ala Glu Ala Val Lys Lys Arg Arg Arg Ala Thr Lys Lys Pro 65 70 75 80 Tyr Ser Arg Ser He Val Gly Ala Ser Leu Glu Val He Gin Lys Lys
85 90 95
Arg Ala Glu Lys Pro Glu Val Arg Asp Ala Ala Arg Glu Ala Ala Leu
100 105 110
Arg Glu He Lys Glu Arg He Lys Lys Thr Lys A.sp Glu Lys Lys Ala 115 120 " 125
Lys Lys A.la Glu Val Ser Lys Ser Gin Lys A.la Gin Thr Lys Gly Ala
130 135 140
Val Gin Lys Gly Ser Lys Gly Pro Lys Leu Gly Gly Gly Gly Gly Lys 145 150 155 160 Arg
(2) INFORMATION FOR SEQ ID NO: 517: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 106 amino acids ,B) TYPE: amine acid lO STRANDEDNESS: (D) TOPOLOGY: linear (ii: MOLECULE TYPE: peptide (ix; FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: I..106
(D) OTHER INFORMATION: / Ceres Seq. ID 1944351 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 517:
Met Tyr Arg Lys Gin His Lys Lys Asp He His Ala Glu Ala Val Lys 1 5 10 15
Lys Arg Arg Arg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly
20 25 " 30
Ala Ser Leu Glu Val He Gin Lys L-τ Arg Ala Glu Lys Pro Glu Val 35 40 45 Arg Asp Ala Ala Arg Glu A.la Ala Leu A.rg Glu He Lys Glu Arg He
50 55 ' 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Ala Glu Val Ser Lys 65 ^0 75 80
Ser Gin Lys Ala Gin Thr Lys Gly Ala Val Gin Lys Gly Ser Lys Gly 85 90 95
Pro Lys Leu Gly Gly Gly Gly Gly Lys Arg
100 105
(2) INFORMATION FOR SEQ ID NO: 518: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 89 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..89
(D) OTHER INFORMATION: / Ceres Seq. ID 1944352 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 518: Met Leu Leu Glu Lys Leu Leu Phe Val Arg Ser Arg Ser Ala Ser Arg 1 5 10 15
Arg Pro Arg Thr Arg A.rg Arg Arg Arg Arg Leu Arg Cys Pro Ser Pro
20 25 30
Arg A.rg A.rg Arg Arg Arg Ala Leu Ser Arg Arg Val Pro Arg Ala Pro 35 40 ' 45
Ser Trp Ala Ala Ala Val Ala Asn Ala Glu Lys Glu Arg Ser Val He 50 55 60 Ser Arg Pro His Gin Ser His Leu Cys Ser Thr Trp Val Asn Phe Ala 65 70 75 80
Phe Ser Phe Arg Val Thr Cys Asp Ser 85 (2) INFORMATION FOR SEQ ID NO: 519: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1035 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A.) NAME/KEY: - (B) LOCATION: I..1035 (D) OTHER INFORMATION: / Ceres Seq. ID 1964011
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:519: aacatataaa ttacgtgctc cetcttcgcc gccgtctctc gcgecgceac ttcccteecg 60 acccactcgc ccaaaaccgt agcgccctcg cctgctcgcc gccgccgtcg ttgcgagctc 120 cccatcttcc tccgttaacc atggcgaccc agatcagcaa gaagaagaag ttcgtcagcg 180 acggcgtgtt ctacqccgag ctcaatgaga tgctgacgcg ggagctegcg gaggacggct 240 actccggcgt qgaggtgcgt gtcacaccga tgegcacgga gatcatcatc cgcgcaacgc 300 GCacgcagaa cgtgctcggc gagaagggcc geagGatcag ggagctcacg tctgtggtcc 360 agaagaggtt caacttcccc gagaacggcg tcgagctcta cgccgaqaag gtcgtcaacc 420 gcggcctctg cgccatcgcg caggctgagt ccetccgcta caagcteetc ggagoecttg 480 ccgtccggag ggcctgctat ggtgttcttc gctttgttat ggagagtggt gccgagggtt 540 gtgaggtcat tgtgagtgga aagctcaggg ctcaaagagc caagtccatg aagtteaagg 600 atggctacat gatctcatct ggtcagccag tgaatgagta catcgactca gctgtgagac 660 acgtcctcct cagacagggt gttctgggta tcaaggtgaa gatcatgctt gactgggacc 720 cgaagggcaa ggttggcccg atcacccctc ttccggacct ggtgaccatc cataccccga 780 aggaggagga cgagctgcgc cctcctgtct tggcagctga ggtctaaggt cccaacagcg 840 tcctegaaat ggcagtttga tcgggtecta gctaggtttg atcttatgat aagggcagtg 900 ctaagacagt tcgttccgtg tcacttctgt ttaaaattaa gttttgccga gacaagctat 960 atgtaccgga tgaaagtgtg gttcc tatt gtatgctctg gaattttatt tttggtatgt 1020 ttattttttt gccct (2) INFORMATION FOR SEQ ID NO:520: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 274 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..274 (D) OTHER INFORMATION: / Ceres Seq. ID 1964012
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 520: His He Asn Tyr Val Leu Pro Leu Arg A.rg Arg Leu Ser A.rg Arg His 1 5 10 15"
Phe Pro Pro Asp Pro Leu Ala Gin Asn Arg Ser Ala Leu Ala Cys Ser 20 25 30
Pro Pro Pro Ser Leu Arg Ala Pro His Leu Pro Pro Leu Thr Met A.la
35 40 45
Thr Gin He Ser Lys Lys Lys Lys Phe Val Ser Asp Gly Val Phe Tyr 50 55 60 Ala Glu Leu Asn Glu Met Leu Thr Arg Glu Leu Ala Glu Asp Gly Tyr 65 70 75 80
Ser Gly Val Glu Val Arg Val Thr Pro Met Arg Thr Glu He He He
85 90 95
Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg Arg He 100 105 110
Arg Glu Leu Thr Ser Val Val Gin Lys Arg Phe Asn Phe Pro Glu Asn 115 120 125 Gly Val Glu Leu Tyr Ala Glu Lys Val Val Asn Arg Gly Leu Cys Ala
130 135 140
He Ala Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly Leu Ala 145 150 155 160 Val Arg Arg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu Ser Gly
165 170 175
Ala Glu Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala Gin Arg
180 185 190
Ala Lys Ser Met Lys Phe Lys Asp Gly Tyr Met He Ser Ser Gly Gin 195 200 " 205
Pro Val Asn Glu Tyr He Asp Ser Ala Val Arg His Val Leu Leu Arg
210 215 220
Gin Gly Val Leu Gly He Lys Val Lys He Met Leu Asp Trp Asp Pro 225 230 235 240 Lys Gly Lys Val Gly Pro He Thr Pro Leu Pro Asp Leu Val Thr He
245 250 255
His Thr Pro Lys Glu Glu Asp Glu Leu A.rg Pro Pro Val Leu Ala A.la
260 265 270
Glu Val
2, INFORMATION FOR SEQ ID NO: 521: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 228 ammo acids ^B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..228
(D) OTHER INFORMATION: / Ceres Seq. ID 1964013 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 521: Met Ala Thr Gin He Ser Lys Lys Lys Lys Phe Val Ser Asp Gly Val 1 10 15 Phe Tyr Ala Glu Leu Asn Glu Met Leu Thr Arg Glu Leu Ala Glu Asp
20 25 30
Gly Tyr Ser Gly Val Glu Val Arg Val Thr Pro Met A.rg Thr Glu He
35 40 45
He He Arg Ala Thr Arg Thr Gin Asn Val Leu Gly Glu Lys Gly Arg 50 55 60~
A.rg He Arg Glu Leu Thr Ser Val Val Gin Lys A.rg Phe A.sn Phe Pro 65 " 70 75 80
Glu Asn Gly Val Glu Leu Tyr Ala Glu Lys Val Val Asn Arg Gly Leu 85 90 95 Cys Ala He Ala Gin Ala Glu Ser Leu Arg Tyr Lys Leu Leu Gly Gly
100 105 110
Leu A.la Val A.rg A.rg Ala Cys Tyr Gly Val Leu Arg Phe Val Met Glu
115 120 125
Ser Gly Ala Glu Gly Cys Glu Val He Val Ser Gly Lys Leu Arg Ala 130 135 140
Gin A.rg Ala Lys Ser Met Lys Phe Lys Asp Gly Tyr Met He Ser Ser
145 150 155 " 160
Gly Gin Pro Val Asn Glu Tyr He Asp Ser Ala Val Arg His Val Leu
165 170 175 Leu Arg Gin Gly Val Leu Gly He Lys Val Lys He Met Leu Asp Trp
180 185 190
Asp Pro Lys Gly Lys Val Gly Pro He Thr Pro Leu Pro Asp Leu Val
195 200 205
Thr He His Thr Pro Lys Glu Glu Asp Glu Leu A.rg Pro Pro Val Leu 210 215 220
Ala Ala Glu Val 225 (2) INFORMATION FOR SEQ ID NO: 522: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 205 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..205
(D) OTHER INFORMATION: / Ceres Seq. ID 1964014 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:522: Met Leu Thr Arg Glu Leu Ala Glu Asp Gly Tyr Ser Gly Val Glu Val 1 5 10 15 Arg Val Thr Pro Met Arg Thr Glu He He He A.rg Ala Thr Arg Thr 20 25 30
Gin Asn Val Leu Gly Glu Lys Gly Arq Arg He Arg Glu Leu Thr Ser
35 40 ' 45
Val Val Gin Lys Arq Phe Asn Phe Pro Glu Asn Gly Val Glu Leu Tyr 50 " ' 55 60
Ala Glu Lys Val Val Asn Arg Gly Leu Cys Ala He Ala Gin Ala Glu 65 7u 75 80
Ser Leu A.rg Tyr Lys Leu Leu Gly Gly Leu A.la Val A.rg A.rg A.la Cys 85 90 95 Tyr Gly Val Leu Arg Phe Val Met Glu Ser Gly Ala Glu Gly Cys Glu
100 105 110
Val He Val Ser Gly Lys Leu Arg Ala Gin A.rg Ala Lys Ser Met Lys
115 120 125
Phe Lys Asp Gly Tyr Met He Ser Ser Gly Gin Pro Val Asn Glu Tyr 130 135 140
He Asp Ser Ala Val Arg His Val Leu Leu Arg Gin Gly Val Leu Gly
145 150 155 160
He Lys Val Lys He Met Leu A.sp Trp Asp Pro Lys GI. Lys Val Gly 165 170 175
Pro He Thr Pro Leu Pro Asp Leu Val Thr He His Thr Pro Lys Glu 180 185 190
Glu A.sp Glu Leu A.rg Pro Pro Val Leu Ala Ala Glu Val 195 200 205
(2) INFORMATION FOR SEQ ID NO:523:
(ϋi SEQUENCE CHARACTERISTICS:
(A) LENGTH: 818 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..818
(D) OTHER INFORMATION: / Ceres Seq. ID 1983854 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 523: gatataagaa accctagcgg agccactaac acagtcgcct ccttcctgcr ccgccgccgc 60 cgccgccgcc gccgctacca ccgcctcgcg gccgcctgcg gctccgcgtt tccgcacgga 120 agttggtgaa ggtttcttga ggctgagaac atggtgctga agacggaact ttgccgcttc 180 agcgscagaa gatttatcct gggaaaggca ttagatttat ccgtgctgat tctcaggtct 240 tcctttttgc caactcgaaa tgcaagcgct acttccacaa ccgcctgaag cctgcaaagc 300 ttacctggac agcaatgtac aggaagcagc acaagaagga tatccatgct gaagcggtaa 360 agaagaggcg ccgcgccacc aagaagccat actccaggtc aattgtgggt gcttccttgg 420 aagtaatcca gaagaagaga gctgagaagc cagaggtccg cgatgctgct agagaagctg 480 ctcttcgtga gatcaaggag cgcatcaaga agaccaagga tgagaagaaa gcgaagaagg 540 cggaggtgag caagtcccag aagacgcaga caaagggtgc ggtccagaag ggttccaagg 600 gccccaagtt gggcggcggt ggtgggaagc gctgaaagaa cttagtgtcg tttetcgaca 660 ttgcagtcgt tccttagcca aagccacttt cgtagaacct gtgttgaatt tgcaagactt 720 attcaagcgt tgcttgtgcg tgctaaatac catggcaaga gaacggattt atatttatgc 780 ctgaaaaaaa tgaccgttca tattcttaac tcatcttg (2) INFORMATION FOR SEQ ID NO: 524: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 106 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..106
(D) OTHER INFORMATION: / Ceres Seq. ID 1983855
(xi , SEζ )UENCE DlSCR. [PTI< SEQ ID 110:524:
MMeett TTyyrr AArrgg LLyyss GGiinn HHiiss LLyyss Lys A.sp He His Ala Glu Ala Val Lys
1 5 10 15
Lys Arg A.rg A.rg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly 20 25 " 30
Ala Ser Leu Glu Val He G Giinn L LiVsS Lys Arg Ala Glu Lys Pro Glu Val 25 40 45
A.rα Asp A.la Ala A.rg Glu AAla _L B. Leu Arg O U He Lys Glu Arg He
50 55 6
Lys Lys .hr Lys A.sp Glu Lys Lys Ala Lys Lys _-*.__.a Glu Val Ser Lys
65 "70 75 80
SSeerr GGiinn Lys Thr Gin Thr Lys Gly Ala Val Gin Lys Gly Ser Lys Gly
85 90 95
Pro Lys u Gly Gly Gly Gly Gly Lys Arg 100 105
(2) I INNFFORMATION FOR SEQ ID NO: 525: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 802 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii; MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..802
(D) OTHER INFORMATION: / Ceres Seq. ID 1990261 (xi; SEQUENCE DESCRIPTION: SEQ ID NO:525: gatataagaa accctagcgg mscactaaya cagtcgcctc cttcctgcgc cgccgccgcc 60 gccgccgcta ccaccgcctc gcggccgcct gcggctccgc gtttccgcac ggaagttggt 120 gaaggtttct tgaggctgag aacatggtgc tgaagacgga actttgccgc ttcagcggcc 180 agaagattta tcctgggaaa ggcattagat ttatccgtgc tgattctcag gtcttccttt 240 ttgccaactc gaaatgcaag cgctacttcc acaaccgcct gaagcctgca aagcttacct 300 ggacagcaat gtacaggaag cagcacaaga aggatatcca tgctgaagcg gtaaagaaga 360 ggcgccgege caccaagaag ccatactcca ggteaattgt gggtgcttcc ttggaagtaa 420 tccagaagaa gagagctgag aagccagagg tccgcgatgc tgctagagaa gctgctcttc 480 gtgagatcaa ggagcgcatc aagaagacea aggatgagaa gaaagcgaag aaggcggagg 540 tgagcaagtc ccagaagacg cagacaaagg gtgcggtcca gaagggttcc aagggcccca 600 agttgggcgg cggtggtggg aagcgctgaa agaacttagt gtcgtttctc gacattgcag 660 tcgttcctta gccaaagcca ctttcgtaga acctgtgttg aatttgcaag acttattcaa 720 gcgttgcttg tgcgtgctaa ataccatggc aagagaacgg atttatattt atgcctgaaa 780 aaaaatgacc gttcatattc tt (2) INFORMATION FOR SEQ ID NO:526: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 161 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..161
(D) OTHER INFORMATION: / Ceres Seq. ID 2061972 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 526: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 15
Pro Gly Lys Gly He Arg Phe He Arg Ala Asp Ser Gin Val Phe Leu
20 25 30
Phe Ala Asn Ser Lys Cys Lys Arg Tyr Phe His A.sn Arg Leu Lys Pro 35 40 45
A.la Lys Leu Thr Trp Thr Ala Met Tyr Arg Lys Gin His Lys Lys Asp
50 55 60
He His Ala Glu Ala Val Lys Lys A.rg Arg Arg Ala Thr Lys Lys Pro 65 70 75 80 Tyr Ser Arg Ser He Val Gly Ala Ser Leu Glu Val He Gin Lys Lys
85 90 95
Arg Ala Glu Lys Pro Glu Val Arg Asp Ala Ala A.rg Glu Ala A.la Leu
100 " 105 110
Arq Glu He Lys Glu Arg He Lys Lys Thr Lys Asp Glu Lys Lys Ala 115 120 " 125
Lys Lys Ala Glu Val Ser Lys Ser Gin Lys Thr Gin Thl Lys Gly A.la
120 135 140
."al Gin Lys Gly Ser Lys Gly Pro Lys Leu Gly Gly Gly Gly Gly Lys 145 150 155 160 A.rg
(2) INFORMATION FOR SEQ ID NO: 527: ,ι) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 106 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..106
(D) OTHER INFORMATION: / Ceres Seq. ID 2061973 ixi) SEQUENCE DESCRIPTION: SEQ ID NO:527:
Met Tyr Arg Lys Gin His Lys Lvs Asp He His Ala Glu Ala Val Lys 1 5 10 15
Lys A.rg A.rg Arg A.la Thr Lys Lys Pro Tyr Ser A.rg Ser He Val Gly
20 25 30
A.la Ser Leu Glu Val He Gin Lys Lys Arg Ala Glu Lys Pro Glu Val 35 40 45 Arg Asp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu Arg He 50 55 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Ala Glu Val Ser Lys
65 70 75 80
Ser Gin Lys Thr Gin Thr Lys Gly Ala Val Gin Lys Gly Ser Lys Gly 85 90 95
Pro Lys Leu Gly Gly Gly Gly Gly Lys Arg 100 105
SEQ TABLE 2 (2) INFORMATION FOR SEQ ID NO:l:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 494 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..494 (D) OTHER INFORMATION: / Ceres Seq. ID 1007802
(xi ) SEQUENCE DESCRIPTION: SEQ ID NO:l: aacaatcgga agaaaggaga agacgaagat gtcgttggta tggttggaag egatgttgcc 60 tctcggaatc atcggtggga tgctctgtat catgggcaat tctcagtact acatccacaa 120 agcttatcat ggccgtccta agcacatcgg ccacgatgaa tgggatgttg ctatggaaag 180 acgcgacaag aaagtcgtcg agaaagctgc agctccttcc tcatgattcg ctttatctct 240 tttgtgttcc teaggggctt aaggtgacca cttgtggtga caaataaagt gcattccaga 300 agaagaagaa gctgggggat ctagtacttt cattcccatt tgattttcc tggacatatt 360 aaagctttca gaaatcagac ctcaataaca tttggtttat caatatttct etattegtga 420 tattttgtat gcttttaagt tgcdtgatac actgaactac tctcttgctg tgtgagtgaa 480 taaatgaata tctc INFORMATION FOR SEQ ID NO: 2:
(i) SEQUENCE CHARACTERISTICS: Α) LENGTH: 94 amino acids ,B) TYPE: amino acid (C) STRANDEDNESS:
D) TOPOLOGY: linear
11) MCLECULE TYPE: peotide ix; FEATURE:
A) NAME/KEY: peptiae
B) LOCATION: 1..94
D! OTHER INFORMATION: : / Ceres Seq. ID 1007503
,xi; ) SEQUENCE DESCRIPTION: SEQ ID NO : 2 :
G" n Ser Glu Glu A.rg Arg Arg A.rg A.rg Cys A.rg Trp Tyr ■__ _ y Trp Lys
1 5 1 15
A.rg Cys Cys Leu Ser Glu Ser Ser Val Gly Cys Ser Val Trp Ala 20 25 30
He Leu Ser Thr Thr Ser Thr Lys Leu He Met Ala Val Leu Ser Thr 35 40 45
Ser A.la Thr Met Asn Gly Me" Leu Leu Trp Lys A.sp Ala Tr.r Arg Lys 50 55 60
Ser Ser Arg Lys Leu Gin Leu Leu Pro His A.sp Ser Leu Tyr Leu Phe
65 70 75 80
Cys Val Pro Gin Gly Leu Lys Val Thr Thr Cys Gly Asp Lys
85 90
INFORMATION FOR SEQ ID NO: 3:
;1] SEQUENCE CHARACTERISTICS: K ) LENGTH: 74 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74 (D) OTHER INFORMATION: / Ceres Seq. ID 100^804 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:3:
Thr He Gly Arg Lys Glu Lys Thr Lys Met Ser Leu Val Trp Leu Glu
5 10 15
Ala Met Leu Pro Leu Gly He He Gly Gly Met Leu Cys _e Met Glv
20 25 ' 30 Asn Ser Gin Tyr Tyr He His Lys Ala Tyr His Gly Arg Pr Lys His
35 40 45' He Gly His Asp Glu Trp Asp Val Ala Met Glu Arg Arg Asp Lys Lys 50 55 60
Val Val Glu Lys Ala Ala Ala Pro Ser Ser
65 70
'2) INFORMATION FOR SEQ ID NO : 4 : (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1007805 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 4: Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He He Gly 1 5 10 15
Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His Lys A.la
20 25 " 30
Tyr His Gly Arg Pro Lys His He Gly His Asp Glu Trp Asp Val Ala 35 40 J 45
Met Glu Arg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala Pro Ser 50 55 60
Ser 65
INFORMATION FOR SEQ ID NO : 5 : i, SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 700 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: .near
Hi) MOLECULE TYPE: DNA > genomic) ;ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..700 (D) OTHER INFORMATION: / Ceres Seq. ID 1008556
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 5: aaaagaaaac tgaagaaccc caaaaatccc nagtgaaaga aaacgttatc eacttcgaga 60 gagtgacacg tcacgaagca aatccaaatt caaaactttt ccataaaaat caaatcactt 120 cttcttatta cttccccaaa tcgaaatcag tcacttatta aaaccctaaa tcatgacgat 180 cgcaccggca ttgcagacga cgttcgtgtc atcaaccaac ttcctgaaac attcttcttc 240 gtggggatca tcatcaceaa acaatgtgat tcttcecaaa aaeaagagat cttctacctc 300 cgtagttgtc gccgccgteg gtgatgtetc ttctgacgga acaatctact taatcggcgg 360 agccatcgcc gttgcactcg tcggaactgc atttccgatc ctcttcaaac gcaaagacac 420 gtgtccggaa tgtgatggag caggatttgt gaggaaagga ggagtgactc tgagagccaa 480 cgccgcacgg aaggatcttc ctcagatcgt ttgtgctaat tgcaatggac tcggaaagct 540 taaccagatt gataaatcat aagtcttctt catatatatg taaaaagctc catttctcat 600 tcctcttctt atctacaata tacctctgta agagtagata gcttcgaatg atcaatggtt 660 gcttggagat ggatggatat atatatacaa ttgctttttt (2) INFORMATION FOR SEQ ID NO: 6: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 129 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A.) NAME/KEY: peptide (B) LOCATION: 1..129
(D) OTHER INFORMATION: / Ceres Seq. ID 1008557 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 6:
Met Thr He Ala Pro A.la Leu Gin Thr Thr Phe Val Ser Ser Thr Asn 1 5 10 15
Phe Leu Lys His Ser Ser Ser Trp Gly Ser Ser Ser Pro A.sn Asn Val 20 25 30 He Leu Pro Lys Asn Lys Arg Ser Ser Thr Ser Val Val Val Ala Ala 35 40 45
Val Gly Asp Val Ser Ser Asp Gly Thr He Tyr Leu He Gly Gly Ala 50 55 60
He Ala Val Ala Leu Val Gly Thr Ala Phe Pro He Leu Phe Lys Arg 65 70 75 80
Lys Asp Thr Cys Pro Glu Cys Asp Gly A.la Gly Phe Val Arg Lys Gly 85 90 95
Gly Val Thr Leu Arg Ala Asn Ala Ala Arg Lys Asp Leu Pro Gin He
100 105 110
Val Cys Ala Asn Cys Asn Gly Leu Gly Lys Leu A.sn Gin He Asp Lys 115 120 " 125 Ser
(2) INFORMATION FOR SEQ ID NO:7:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 665 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear iii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: .'A) NAME/KEY: - 3) LOCATION: 1..665
(D) OTHER INFORMATION: / Ceres Seq. ID 1008628 i i) SEQUENCE DESCRIPTION: SEQ ID NO: 7: atgttactct tctcagatct cttgttcgtt ttgatgtaca atggcgtcct tggtagcagc 60 tcctatctct ttctcaggtg actetcatgt caaagcacac cgaaacttca atgcgattcg 120 eaagagctct acattgactg ttcaaacaaa atcaaaccgc agtcacaaac tctcggtttc 180 tgcaggttac cgtgggggaa gtaagggtgg tggaagtagt gattttgtta ccggttttct 240 tctaggaagt getgtgttcg gaactctggc ttatatcttt getccacaga tccgaagatc 300 agtgctgagc gagaatgaat atggtttcaa gaaaccggag cagccgatgt actatgacga 360 aggcctagag gagagaagag agatattgaa tgagaaaatc ggccaactca attccgccat 420 tgacaaggtt tegtcgcgtc tgaaaggagg tcggagcggt agcagcaaga acacttcttc 480 gccgtctgtc ccagttgaaa ccgacgcaga agcagaagct actgcatgat tgaatgtaat 540 cctctgctct attttaccaa ttcaaaactg ccttccattg gttctgtggt tttttttttt 600 tttttgttgg aaccattagg ggcttttctg acttttagat attgaaagaa aaagacaatc 660 gtcgc
(2) INFORMATION FOR SEQ ID NO : 8 :
(l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 162 ammo acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..162
(D) OTHER INFORMATION: / Ceres Seq. ID 1008629 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 8: Met A.la Ser Leu Val Ala Ala Pro He Ser Phe Ser Gly A.sp Ser His 1 5 10 15 Val Lys Ala His Arg Asn Phe Asn Ala He Arg Lys Ser Ser Thr Leu 20 25 30
Thr Val Gin Thr Lys Ser A.sn Arg Ser His Lys Leu Ser Val Ser Ala
35 40 45
Gly Tyr Arg Gly Gly Ser Lys Gly Gly Gly Ser Ser Asp Phe Val Thr 50 55 " 60
Gly Phe Leu Leu Gly Ser Ala Val Phe Gly Thr Leu Ala Tyr He Phe 65 70 75 80
Ala Pro Gin He Arg Arg Ser Val Leu Ser Glu Asn Glu Tyr Gly Phe 85 90 95 Lys Lys Pro Glu Gin Pro Met Tyr Tyr Asp Glu Gly Leu Glu Glu Arg 100 105 110
Arg Glu He Leu Asn Glu Lys He Gly Gin Leu Asn Ser Ala He Asp 115 120 125
Lys Val Ser Ser Arg Leu Lys Gly Gly Arg Ser Gly Ser Ser Lys Asn
130 135 140
Thr Ser Ser Pro Ser Val Pro Val Glu Thr Asp Ala Glu Ala Glu Ala 145 150 155 160
Thr A.la
(2) INFORMATION FOR SEQ ID NO: 9: i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1101 base pairs
( B ) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear n) MOLECULE TYPE: DNA (genomic) ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1101
(D) OTHER INFORMATION: / Ceres Seq. ID 1009376 xi; SEQUENCE DESCRIPTION: SEQ ID NO : 9 : cttctt cct ctttcttctt tctgttttct ggtcgctcgt tacccccaag acctcotcga 60 ggtttetttc tetctgaaaa agtgcttttg etgcgtttcc atgcte egg aaggaacttg 120 gctgaatcgt tggaggatta tcgatctggc gtcgttggtg catctctagc tgcgccaatt 180 eatcggatcc ggtttgattt ctccetttcg cgaatctagc cttcegtgat ettagccatg 240 ttctatggca cagctgtatg ggacccttgg cttatcgttg gccagattat ttgcctccaa 300 tgctcttact atctcactct tggactcttc accatggtct ttcttggcct tcgtgttcct 360 cgccttagtc ttgtctactt cttcgattac gctactctca ctacttccac cttcaccggt 420 tggtctgtta ttgcctcatt cctcttctct tcactcgctg gggctgtgta catgatattt 480 ttggtggagc gagcacggaa atgcttagat ttctctgcaa ctctctacat catacatctc 540 ttcttttgca tcatgtatgg aggatgqcct tcctctatgg cgtggtgggt tgttaatgga 600 accggactcg ctgttatggc tttgctagct gagtacttgt gcattaaacg cgaacagcga 660 gagatcecta tggatcgctt ccactcaagg gtttgaagat tggtgaaaga acaagtgatg 720 aagattcttg tgggttagca gcgcgactcg tagagcctag tagagcctag tactcttaac 780 aattgtgatg tacagagatg aaatcagagg agtagaatgg gcgaaaggaa gttcagctag 840 ccaagcaaca atgttggaca ctggtgcacc aactctgact gcaattttta gtgacttcaa 900 atactaagac tttggaatac gtttcaattt gttcttttgt atgaaaaaaa cattagactc 960 gaataggtta ttgatttcat gttgcttctt ttttttgttt atactggatt ttctcttcta 1020 tcctctactt ggtgcagctt tgtgtgtttt aaaaccagtg tctcattcat catactcttt 1080 taccaccaat toaatccttc c (2) INFORMATION FOR SEQ ID NO:10: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 152 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide iix) FEATURE:
(A.) NAME/KEY: peptide (B) LOCATION: 1..152
(D) OTHER INFORMATION: / Ceres Seq. ID 1009377 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 10:
Met Phe Tyr Gly Thr Ala Val Trp A.sp Pro Trp Leu He Val Gly Gin 1 5 10 15
He He Cys Leu Gin Cys Ser Tyr Tyr Leu Thr Leu Gly Leu Phe Thr 20 25 30 Met Val Phe Leu Gly Leu Arg Val Pro Arg Leu Ser Leu Val Tyr Phe 35 40 45
Phe Asp Tyr Ala Thr Leu Thr Thr Ser Thr Phe Thr Gly Trp Ser Val
50 55 60
He A.la Ser Phe Leu Phe Ser Ser Leu Ala Gly Ala Val Tyr Met He 65 70 75~ 80
Phe Leu Val Glu Arg Ala Arg Lys Cys Leu A.sp Phe Ser A.la Thr Leu 85 " 90 95 Tyr He He His Leu Phe Phe Cys He Met Tyr Gly Gly Trp Pro Ser
100 105 110
Ser Met Ala Trp Trp Val Val Asn Gly Thr Gly Leu Ala Val Met Ala 115 120 125 Leu Leu Ala Glu Tyr Leu Cys He Lys Arg Glu Gin Arg Glu He Pro 130 135 140
Met A.sp Arg Phe His Ser Arg Val 145 150
(2) INFORMATION FOR SEQ ID NO: 11: n) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 120 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..120
;D) OTHER INFORMATION: Ceres Seq. ID 1009378 xi! SEQUENCE DESCRIPTION: SEQ ID NO : 11 :
Met ""al Phe Leu Gly Leu A.rg 'al He A.rg Leu Ser Lei Val Tyr Phe 1 Ξ ' ' lo" 15
Phe Asp Tyr Ala Thr Leu Thr Thr Ser Thr Phe Thr Gly Trp Ser Val 20 25 30 He Ala Ser Phe Leu Phe Ser Ser Leu Ala Gly Ala Val Tyr Met He 35 40 45
Phe Leu Val Glu Arg A.la A.rg Lys Cys Leu Asp Phe Ser A.la Thr Leu
50 55 60
Tyr He He His Leu Phe Phe Cys He Met Tyr Gly Gly Trp Pro Ser 65 70 75 80
Ser Met Ala Trp Trp Val Val A.sn Gly Thr Gly Leu Ala Val Met Ala
85 "* 90 95
Leu Leu Ala Glu Tyr Leu Cys He Lys Arg Glu Gin Arg Glu He Pro 100 105 110 Met A.sp Arg Phe His Ser Arg Val 115 120
'2; INFORMATION FOR SEQ ID NO: 12: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 76 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..76
(D) OTHER INFORMATION: / Ceres Seq. ID 1009379 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 12: Met Ala Gin Leu Tyr Gly Thr Leu Gly Leu Ser Leu Ala Arg Leu Phe 1 5 10 15
A.la Ser Asn Ala Leu Thr He Ser Leu Leu Asp Ser Ser Pro Trp Ser
20 25 30
Phe Leu Ala Phe Val Phe Leu A.la Leu Val Leu Ser Thr Ser Ser He 35 40 45 Thr Leu Leu Ser Leu Leu Pro Pro Ser Pro Val Gly Leu Leu Leu Pro 50 55 6θ"
His Ser Ser Ser Leu His Ser Leu Gly Leu Cys Thr 65 70 75
(2) INFORMATION FOR SEQ ID NO: 13: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 398 base pairs
(B) TYPE: nucleic acid ( C ) STRANDEDNESS: single
( D ) TOPOLOGY: linear
( i i ) MOLECULE TYPE DNA (genomic) ( ix ) FEATURE :
(A) NAME/KEY
(B) LOCATION 1..398
(D) OTHER INFORMATION: / Ceres Seq. ID 1011128 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 13: aaatcaatag cttatctagt tcttgactgt tcaacgatca atggcaccat ccgctgcaat 60 gctcatactc teacatccte tagttagcca caaagctaag aatcaatctc tgtcatcgcc 120 gtcgtctgtt aagtcgacac gtgtcttcgg ttttctttgg ccttggaagg cattagacaa 180 tgaggatcat tccgcggttg ttctaggccg gctctttggc gatccggcta ctatcgagaa 240 gcgcttceaa gaagctcttg aacaaagctg ttggtaattt gtacaatgtt tggttgggtt 300 tattgattgt ttttacgtta aaatcgcttt tataaattgg aaattgaagt actgtaaaat 360 gtaaaaattg actatatata attaaaggta cattatgc
.^; INFORMATION FOR SEQ ID NO: 14: ; ) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 78 amino acids
(B) TYPE: amino acid I'C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix: FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..78 (D) OTHER INFORMATION: / Ceres Seq. _ ) 1011129
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 14:
Met Ala Pro Ser A.la Ala Met Leu He Leu Ser Hi. Pro Leu Val Ser
1 5 10 15
His Lys Ala Lys Asn Gin Ser Leu Ser Ser Pro Ser Ser Val Lys Ser 20 25 30
Thr Arg Val Phe Gly Phe Leu Trp Pro Trp Lys Ala Leu Asp Asn Glu
35 40 45
Asp His Ser Ala Val Val Leu Gly Arg Leu Phe Gly Asp Pro Ala Thr
50 55 60
He Glu Lys Arg Phe Gin Glu Ala Leu Glu Gin Ser Cys Trp 65 " "70 75
(2) INFORMATION FOR SEQ ID NO: 15: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 72 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..72
(D) OTHER INFORMATION: / Ceres Seq. ID 1011130 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 15: Met Leu He Leu Ser His Pro Leu Val Ser His Lys Ala Lys Asn Gin 1 5 10 15
Ser Leu Ser Ser Pro Ser Ser Val Lys Ser Thr Arg Val Phe Gly Phe
20 25 30
Leu Trp Pro Trp Lys Ala Leu Asp Asn Glu Asp His Ser Ala Val Val
35 40 45
Leu Gly Arg Leu Phe Gly Asp Pro Ala Thr He Glu Lys Arg Phe Gin
50 55 60
Glu A.la Leu Glu Gin Ser Cys Trp 65 70
(2) INFORMATION FOR SEQ ID NO: 16: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 549 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..549
(D) OTHER INFORMATION: / Ceres Seq. ID 1011718 (xi) SEQUENCE DESCRIPTION: SEQ ID NO : 16 : agggatgtag taggccaata ggcaaatcag agaatcacaa atggtatctg gtcaagaaga 60 ttcctgtttg tctgcagatg catgtgtgta atctagggta tatgtttttg tccatttggt 120 ttcataaggc aataaagr.tc cagctattta ctacttgtga agaaaaaagt gagggaaaac 180 agagtcaagt ccgattactt ttctgggaaa gctgaggatt ttgtgttctt agagagcaga 240 tgaagaggtg actgttgttt ctggtgagat agaagttggc atetaaattt gctttetctg 300 gaccagtgaa atcaattgca gtctcetata tattgtagta ggcgatgtat cagtggtgaa 360 gcgaggatga catctgtggg tacttgttct taatccttca ctctgatatc tatgctttag 420 aagcgtttca agttcatgaa gctgatttga tgttgagttt ttaacaacaa gaatcaattc 480 actccaaaaa tatgtaaact etgccatgcc ttgagctgct ttttggatta tccactgttt 540 tgttttgtg 2 ) INFORMATION FOR SEQ ID NO: 17: ■'i; SEQUENCE CHARACTERISTICS:
(A) LENGTH: 70 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..70
(D) OTHER INFORMATION: / Ceres Seq. ID 1011719 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 17: Gly Cys Ser Arg Pro He Gly Lys Ser Glu Asn His Lys Trp Tyr Leu
10 15
Val Lys Lys He Pro Val Cys Leu Gin Met His Val Cys Asn Leu Gly
20 25 30 Tyr Met Phe Leu Ser He Trp Phe His Lys Ala He Lys He Gin Leu 35 40 45
Phe Thr Thr Cys Glu Glu Lvs Ser Glu Glv L\ Gin Ser Gin Val Arg
50 55 60 Leu Leu Phe Trp Glu Ser
65 70
(2) INFORMATION FOR SEQ ID NO: If (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 45 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..45 (D) OTHER INFORMATION: / Ceres Seq. ID 1011720
(XI) SEQUENCE DESCRIPTION: SEQ ID NO: 18:
Met His Val Cys Asn Leu Gly Tyr Met Phe Leu Ser He Trp Phe His
1 5 10 15
Lys Ala He Lys He Gin Leu Phe Thr Thr Cys Glu Glu Lys Ser Glu 20 25 30
Gly Lys Gin Ser Gin Val Arg Leu Leu Phe Trp Glu Ser 35 40 45
(2) I INNFFOC 3RRMMAAT' ION FOR SEQ ID NO: 19: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 37 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A.) NAME/KEY: peptide (B) LOCATION: 1..37
(D) OTHER INFORMATION: / Ceres Seq. ID 1011721 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 19: Met Phe Leu Ser He Trp Phe His Lys Ala He Lys He Gin Leu Phe 1 5 10 15
Thr Thr Cys Glu Glu Lys Ser Glu Gly Lys Gin Ser Gin Val Arg Leu
20 25 30
Leu Phe Trp Glu Ser 35
(2) INFORMATION FOR SEQ ID MO: 20: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 417 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear ii) MOLECULE TYPE: DNA I genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..417
(D) OTHER INFORMATION: / Ceres Seq. ID 1011735 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 20: aattccttct ttttcacatc tacccaaaat tccaaaacac catcgatttt ttgctctctt 60 gaaatgctet ttttatgtcc aattettctc ttccaactaa accgaaccgg aaaaccaggt 120 tcggagatcg gtgtttactg atggccaaac agcaacgaac ccgactttac atactccgaa 180 gatgtgtctc catgctgctt tgctggcacg accactctat ttctgattag tttgcagtca 240 tgaaccggac tgaccaagaa gtagcaatca gaagaatgtg atgtcattta gagttttttc 300 ttgttttctt ttagaactct cttcagggaa tcttttgtaa ttgaagaaga ctctaaggat 360 tgggcctttt gggcctttgt acatattgtg taaataacat atgaactttt tttaccc (2) INFORMATION FOR SEQ ID NO:21: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 51 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..51 (D) OTHER INFORMATION: / Ceres Seq. ID 1011736
(xi) SEQUENCE DESCRIPTION: SEQ ID MO: 21: Met Ser A.sn Ser Ser Leu Pro Thr Lys Pro A.sn A.rg Lys Thr A.rg Phe 1 5 10 15
Gly Asp Arg Cys Leu Leu Met Ala Lys Gin Gin Arg Thr Arg Leu Tyr 20 25 30
He Leu A.rg Arg Cys Val Ser Met Leu Leu Cys Trp His A.sp His Ser
35 40 45
He Ser Asp 50 (2) INFORMATION FOR SEQ ID NO: 22: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 46 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..46
(D) OTHER INFORMATION: / Ceres Seq. ID 1011737 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:22: A.sn Ser Phe Phe Phe Thr Ser Thr Gin A.sn Ser Lys Thr Pro Ser He 1 5 10 15
Phe Cys Ser Leu Glu Met Leu Phe Leu Cys Pro He Leu Leu Phe Gin
20 25 30
Leu Asn Arg Thr Gly Lys Pro Gly Ser Glu He Gly Val Tyr 35 40 45
(2 INFORMATION FOR SEQ ID NO: 23: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 32 amino acids vB) TYPE: ammo acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear ii; MOLECULE TYPE- peptide (ix) FEA.TURE:
A; NAME/KEY: peptide ■ B LOCATION: i ..32
,1 OTHER INFORMATION: - lares See. ID Hl!~28 xi; SEQUENCE DESCRIPTION: SEQ ID MO: 23: He Pre Ser Phe Ser His Leu Pro Lys He Pre Lys His His Arg Phe 1 5 10 15 Phe Ala Leu Leu Lys Cys Ser Phe Tyr Val Gin Phe Phe Ser Ser Asn
20 25 30
(2 INFORMATION FOR SEQ ID NO: 24: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 712 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..712
'D) OTHER INFORMATION: / Ceres Seq. ID 1011755 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 24: actcaaatag atgaagaaat ggcgagctta agcacgagct tgctcggaat aagacgaggg 60 tcaagtaaca agaacaaggc agaagataag e.ecaaaaacc agtgttttgc aagaagcatc 120 caaagcatag acaatcacct ggtgtttgtt ctctttgtct taacgagagg ctctctcttt 180 ttatcaaagc agcttcttca cgtagaccaa gatctcgtca aatcttgtct acttcttcct 240 caactacttc ctctctttca tctgacggtt cttcttctgt ctcttcttgt ccttctccta 300 ttgttgatcg cegacgatac ttgttaatgt eeggaggcag cggtagagga gagaaagtga 360 tttcgtggat gacgaaaagc cgatccgtag ettataaagt ggatgatgag aaaagaagga 420 agaagaagac aaagacgaat agtggtttct tttttggttt ggtaatgggc acaaagaaga 480 gacaataaga tagtcagtct tgtagatttg ttagattaga ttgttcttga ttgtgtattt 540 tcttgattct ttcattttag attgattgct acatatagat gactagatca gtttggtggg 600 tacgtgcaag tgagagagat tctttatacg tattcttgtg attgattccc taagcttgta 660 gtttagtgtg gtaacataaa atgtgataat ccagatttaa tatgcgttga ac (2) INFORMATION FOR SEQ ID NO: 25: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 108 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..108
(D) OTHER INFORMATION: / Ceres Seq. ID 1011756 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 25: Thr Gin He Asp Glu Glu Met Ala Ser Leu Ser Thr Ser Leu Leu Gly
1 5 10 15
He Arg Arg Gly Ser Ser Asn Lys Asn Lys Ala Glu Asp Lys Thr Lys
20 25 30
Asn Gin Cys Phe Ala Arg Ser He Gin Ser He Asp Asn His Leu Val
35 40 45
Phe Val Leu Phe Val Leu Thr Arg Gly Ser Leu Phe Leu Ser Lys Gin 50 55 60
Leu Leu His Val Asp Gin Asp Leu Val Lys Ser Cys Leu Leu Leu Pro
65 70 5 80
Gin Leu Leu Pro Leu Phe His Leu Thr Val Leu Leu Leu Ser Leu Leu 85 90 95
Val Leu Leu Leu Leu Leu He Ala A.sp A.sp Thr Cys 100 105
(2) INFORMATION FOR SEQ ID NO: 26:
; SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 102 amino acids
(B. TYPE: amino acid 'C) STRANDEDNESS: • D) TOPOLOGY: linear
■ii MOLECULE TYPE: peptide >ιx; FEATURE:
(Al NAME/KEY: peptide (B) LOCATION: 1..102 (D) OTHER INFORMATION: / Ceres Seq. ID 1011757
(xi, SEQUENCE DESCRIPTION: SEQ ID NO: 26: Met A.la Ser Leu Ser Thr Ser Leu Leu Gly He Arg A.rg Gly Ser Ser 1 5 10 15
Asn Lys Asn Lys Ala Glu Asp Lys Thr Lys Asn Gin Cys Phe Ala Arg 20 25 30
Ser He Gin Ser He Asp Asn His Leu Val Phe Val Leu Phe Val Leu
35 40 45
Thr A.rg Gly Ser Leu Phe Leu Ser Lys Gin Leu Leu His Val Asp Gin 50 55 60 Asp Leu Val Lys Ser Cys Leu Leu Leu Pro Gin Leu Leu Pro Leu Phe 65 70 75 80
His Leu Thr Val Leu Leu Leu Ser Leu Leu Val Leu Leu Leu Leu Leu
85 90 95
He Ala Asp Asp Thr Cys 100
(2) INFORMATION FOR SEQ ID NO:27: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 422 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..422
(D) OTHER INFORMATION: / Ceres Seq. ID 1011832 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:27: aataacaata tcaaaagata aaaacagagt ttgcttttat aagatcaaag aaggtaaaaa 60 aaaaaagtgg caaaatggag tgcgatcgta ttgataatga tggtgatgat tgttgcggtc 120 acaatagaag cacaagaaga aagtggttgg actatttgtt ttcgccaatg ttctcagcct 180 tgtcgcagtg acgacggtag ttgctatgaa aactgtaaaa tcgaatgcgg tggtcccaag 240 cctcccttat ctcgtctacg aagctcacat gcatgagatg gcatcatcaa tggaagttcg 300 cggaaggata ggatgataaa aagagatttg tagcggattt ttgatcatct ctactgtttt 360 taacttcacg ttttatatta taagagtttc attaaaaaga tcaataaaac gagaaaatgt 420 gg
(2) INFORMATION FOR SEQ ID NO: 28: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 59 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 1011833 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 28:
Met Met Val Met He Val Ala Val Thr He Glu Ala Gin Glu Glu Ser 1 5 10 15
Gly Trp Thr He Cys Phe Arg Gin Cys Ser Gin Pro Cys A.rg Ser Asp 20 ' 25 30 Asp Gly Ser Cys Tyr Glu Asn Cys Lys He Glu Cys Gly Gly Pro Lys 35 40 45
Pro Pro Leu Ser A.rg Leu A.rg Ser Ser His Ala
50 55
(2: INFORMATION FOR SEQ ID NO: 29: i, SEQUENCE CHARACTERISTICS:
(A) LENGTH: 58 ammo aciαs
(B) TYPE: amino acid
(C) STPA.NDEDNESS:
(D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..58
(D) OTHER INFORMATION: / Ceres Seq. ID 1011834 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:29:
Met Val Met He Val Ala Val Thr He Glu Ala Gin Glu Glu Ser Gly 1 5 10 15
Trp Thr He Cys Phe Arg Gin Cys Ser Gin Pro Cys Arg Ser Asp Asp 20 25 30 Gly Ser Cys Tyr Glu Asn Cys Lys He Glu Cys Gly Gly Pro Lys Pro 35 40 45
Pro Leu Ser Arg Leu A.rg Ser Ser His Ala
50 55
(2) INFORMATION FOR SEQ ID NO: 30: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 56 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..56
(D) OTHER INFORMATION: / Ceres Seq. ID 1011835 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 30:
Met He Val Ala Val Thr He Glu Ala Gin Glu Glu Ser Gly Trp Thr 1 5 10 15
He Cys Phe Arg Gin Cys Ser Gin Pro Cys Arg Ser Asp Asp Gly Ser 20 25 30 Cys Tyr Glu Asn Cys Lys He Glu Cys Gly Gly Pro Lys Pro Pro Leu 35 40 45
Ser Arg Leu A.rg Ser Ser His Ala
50~ 55
(2) INFORMATION FOR SEQ ID NO:31: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 713 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..713
(D) OTHER INFORMATION: / Ceres Seq. ID 1011907 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:31: aattctggtt tttcttgcaa tgcttcttcc atttctctcc tcctctctcc tcctccgtct 60 ctcttctccg atcatgtccc ctgatcceaa atccaatacc ttcttcttct ctttttccaa 120 ttgattaccg gagaatttca gatcgcgatc tccgatttat taataattac agaaaaaaat 180 aattaaaccc tagagagaga gagagatata tatatacatg gagagttcat taggtttcat 240 ggcggttttc gccgtctcag gaagcgttgt gttcttagcg agtcaatttc acaagcgtct 300 tctctccgat tacatggaca agttcgaatt cgaaatccga gcgcagaaaa aaatggtgat 360 gaagaagaag gtgagattcg cggcggatgt ggtggagccg tcggggaata acaaagagta 420 tcgccggaga cattcttcca aggctaaatc gaattcgaag atggcggcaa ctatttgact 480 ttaaggtttt ttgtacaaaa tttaatgtgt aatttattca tttgggtttt tgtgatttga 540 aattcgtaaa tttaatttcg gaatctgaat ctgggctaaa cttttcaagt cttccceagg 600 gtcaattctt tttcttcttc ttttttttct tgaggggttt ttttttgttg ttgtgacctg 660 taaataaatg tgttgtttgt gtatatacaa aatgtgattg ctaattacct ttt 2 , INFORMATION FOR SEQ ID NO: 22: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 86 ammo acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..86
(D) OTHER INFORMATION: / Ceres Seq. ID 1011908 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 32: Met Glu Ser Ser Leu Gly Phe Met Ala Val Phe Ala Val Ser Gly Ser 1 5 10 15 Val Val Phe Leu Ala Ser Gin Phe His Lys Arg Leu Leu Ser Asp Tyr
20 25 30
Met Asp Lys Phe Giu Phe Glu He Arg Ala Gin Lys Lys Met Val Met
35 40 " 45
Lys Lys Lys Val Arg Phe Ala Ala Asp Val Val Glu Pro Ser Gly Asn 50 55 60
A.sn Lys Glu Tyr Arg Arg Arg His Ser Ser Lys Ala Lys Ser Asn Ser 65 70 75 80
Lys Met Ala Ala Thr He 85 (2) INFORMATION FOR SEQ ID NO: 33: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 79 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..79 (D) OTHER INFORMATION: / Ceres Seq. ID 1011909
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:33:
Met Ala Val Phe Ala Val Ser Gly Ser Val Val Phe Leu Ala Ser Gin 1 5 10 15
Phe His Lys Arg Leu Leu Ser Asp Tyr Met Asp Lys Phe Glu Phe Glu 20 25 30
He Arg Ala Gin Lys Lys Met Val Met Lys Lys Lys Val Arg Phe Ala 35 40 45 Ala Asp Val Val Glu Pro Ser Gly Asn Asn Lys Glu Tyr Arg Arg Arg
50 55 60
His Ser Ser Lys Ala Lys Ser Asn Ser Lys Met Ala Ala Thr He 65 70 75 (2) INFORMATION FOR SEQ ID NO: 34: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
Hi) MOLECULE TYPE: peptide Ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59 (D) OTHER INFORMATION: / Ceres Seq. ID 1011910
>xι) SEQUENCE DESCRIPTION: SEQ ID NO: 34: Phe Trp Phe Phe Leu Gin Cys Phe Phe His Phe Ser Pro Pro Leu Ser 1 " 5 10 15
Ser ≤er Val Ser Leu Leu Arg Ser Cys Pro Leu He Pro Asn Pro He 20 ' 25 30
Pre ≤er Ser Ser Leu Phe Fro He Asp Tyr A.rg A.rg He Ser A.sp A.rg
35 40 45
A.sp Leu A.rg Phe He A.sn Asn Tyr Arg Lys Lys 50 55 (2) INFORMATION FOR SEQ ID NO: 35: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 580 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..580 (D) OTHER INFORMATION: / Ceres Seq. ID 1011911
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 35: aattgtttta aaattacaaa ttagtccgtt cttttattcc cgtactcgtt ccttcttctt 60 cttcttcctc tcatcgtcat tttctcgatt ctcactcttc cggtcaccga ctaattctga 120 ataaggttta tcaaaagaat aagaataagt ggataaaaag ctagctttga aagagttatt 180 gcagagaaaa aaaatgggat cgagagggat tatcaacgat aagtggtcaa tgaggattct 240 atggggttgt gctatcggaa gtgctattgg tttatacatg gttgctgtag agagacaaac 300 tcagaacagg gctcgtgcta tggctgagag tttgagagct gctgaatcac aaggtgatgg 360 tgataatgtc taatatctac caagtagtgc tcagttgaat actctcagtt gagttttttt 420 ttttggtgtt tgtttttgtt ataatgactt cttctgccaa gatggtgttg atgtagtttc 480 ttttttgcaa ataatcgtaa taaggtttcg aaacttggag agttgaagtt gctgaacata 540 cgatttgtgt tatcgcaaaa aaagttattt cttatgcctg (2) INFORMATION FOR SEQ ID NO: 36: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 1011912 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 36: Met Gly Ser Arg Gly He He Asn Asp Lys Trp Ser Met Arg He Leu 1 " 5 10 15
Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr Met Val Ala Val 20 25 30 Glu Arg Gin Thr Gin Asn Arg Ala Arg Ala Met Ala Glu Ser Leu Arg
35 40 45
Ala Ala Glu Ser Gin Gly Asp Gly Asp Asn Val
50 55
(2) INFORMATION FOR SEQ ID NO: 37: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 47 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide
( ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 1011913
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 37:
Met Arg He Leu Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr
1 5 10 15
Met Val Ala Val Glu Arg Gin Thr Gin Asn Arg Ala Arg Ala Met Ala 20 25 30
Glu Ser Leu A.rg A.la Ala Glu Ser Gin Gly Asp Gly A.sp Asn Val 35 40 45
(2) INFORMATION FOR SEQ ID NO: 38:
(i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 40 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide
(ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..40
(D) OTHER INFORMATION: / Ceres Seq. ID 1011914
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 38: H Hee V Vaall L Leeuu LLyyss LLeeuu GGiinn HHee SSeerr PPrroo PPhhee PPhhee TTyyrr SSeerr AArrgg TThhrr Arg
1 5 10 15
Ser Phe Phe Phe Phe Phe Leu Ser Ser Ser Phe Ser Arg Phe Ser Leu
2200 2255 3300
P Phhee A Arrqg S Seerr PPrroo TThhrr AAssnn SSeerr GGlluu 35 40
(2) INFORMATION FOR SEQ ID NO: 39:
(i)i SEQUENCE CHARACTERISTICS:
(A) LENGTH: 415 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..415
(D) OTHER INFORMATION: / Ceres Seq. ID 1011954 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 39: tcacaaaacc tgattgttct gtttcgaacc gatagattcg aaccttggtt taagttgecg 60 gcttcgagga atctccggtg tggactttca ctcctgtttc ttcttcatga cgcaagctgt 120 tttctctaga atacgctttc ttagaaccct ggaaaacgtt acccagcttc ctcaatcctc 180 tagctctagc tcgaagaaca tcctttgaaa cacttggatc tttaagcacc gcttggcaga 240 cacgagataa ggttgattcg atgtcaacaa catttatttg ccaaagggat tgaagcattg 300 catccttttt agcttcaatg gctttctgaa tatgtctctg atctttgtga ttgtgatgat 360 catgcatgtc ctatcgttgc gatgtatttt ataaatgttc gtctgtaagt tattt (2) INFORMATION FOR SEQ ID NO: 40: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 42 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..42
(D) OTHER INFORMATION: / Ceres Seq. ID 1011955 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:40: Ser Gin A.sn Leu He Val Leu Pne Arg Thr Asp Arg Phe Glu Pro Trp 1 5 10 15
Phe Lys Leu Pro Ala Ser Arg A.sn Leu A.rg Cys Gly Leu Ser Leu Leu
20 25 30
Phe Leu Leu His Asp Ala Ser Cys Phe Leu 35 40
(2) INFORMATION FOR SEQ ID NO: 41: (x SEQUENCE CHARACTERISTICS:
\A) LENGTH: 33 ammo acids C, STRANDEDNESS:
D) TOPOLOGY: linear 'ii' MOLECULE TYPE: peptiαe (ix) FEATURE:
(A.) NAME/KEY: peptide iB) LOCATION: 1..33
(D) OTHER INFORMATION: / Ceres Seq. ID 1011956 <xι) SEQUENCE DESCRIPTION: SEQ ID NO : 41 : Met Thr Gin Ala Val Phe Ser Arg He Arg Phe Leu Arg Thr Leu Glu 1 5 10 15 Asn Val Thr Gin Leu Pro Gin Ser Ser Ser Ser Ser Ser Lys Asn He
20 25 30
Leu
(2) INFORMATION FOR SEQ ID NO: 42: (l) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 440 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..440
(D) OTHER INFORMATION: / Ceres Seq. ID 1011960 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:42: gacagtcagt cactgtaaca ttttagatct ttcccgaaga agaaaacgaa gaagagacga 60 agagagaaat gaggccgatg cagctggata tgttatcgga gatggatgat gcaggttctt 120 cgatggccat ggacgttgat gacctcgaag ccatggagat actcaacgaa ggaggacttg 180 tctcagataa caagctcgcc gacgccgatt tcttcaacaa attcgatgat gatttcgatg 240 acaccgatat caactaaatc cggttaagtt ttctctttaa gatttcagtt ttttttccta 300 aacttgatgt aatttgtgga gaaacctatg tagtaagtgt gtaataagtt ctgggatttt 360 tatgtttgtg gtatgtaaca atgtttttct tcatttggat tactaaaaca tttgatttgt 420 gtgttattgt gctttgtctg (2) INFORMATION FOR SEQ ID NO: 43: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 62 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..62
(D) OTHER INFORMATION: / Ceres Seq. ID 1011961 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 43: Met Arg Pro Met Gin Leu Asp Met Leu Ser Glu Met Asp Asp Ala Gly 1 5 10 15
Ser Ser Met Ala Met Asp Val Asp Asp Leu Glu Ala Met Glu He Leu
20 25 30
Asn Glu Gly Gly Leu Val Ser A.sp Asn Lys Leu Ala Asp Ala Asp Phe 35 40 45 Phe A.sn Lys Phe Asp Asp Asp Phe Asp Asp Thr Asp He Asn 50 55 60
2) INFORMATION FOR SEQ ID NO: 44: ,:, SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
_.. FEATURE: Α) NAME/KEY: peptiae
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 1011962 >xι, SEQUENCE DESCRIPTION: SEQ ID NO: 44: Met Gin Leu Asp Met Leu Ser Glu Met Asp Asp A a Gly Ser Ser Met 1 5 10 15
A.la Met A.sp Val Asp Asp Leu Glu Ala Met Glu He Leu Asn Glu Gly
20 25 30
Gly Leu Val Ser Asp Asn Lys Leu Ala Asp Ala A.sp Phe Phe Asn Lys 35 40 45 Phe A.sp Asp Asp Phe Asp Asp Thr Asp He Asn 50 55
(2) INFORMATION FOR SEQ ID NO: 45: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 55 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii, MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..55
(D) OTHER INFORMATION: / Ceres Seq. ID 1011963 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 45: Met Leu Ser Glu Met Asp Asp Ala Gly Ser Ser Met Ala Met Asp Val 1 5 10 15
Asp Asp Leu Glu A.la Met Glu He Leu Asn Glu Gly Gly Leu Val Ser
20 25 30
Asp A.sn Lys Leu Ala Asp Ala Asp Phe Phe A.sn Lys Phe Asp Asp Asp 35 40 45 Phe Asp Asp Thr Asp He Asn 50 55
(2) INFORMATION FOR SEQ ID NO: 46: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 193 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..193
(D) OTHER INFORMATION: / Ceres Seq. ID 1014075 (xi) SEQUENCE DESCRIPTION: SEQ ID NO : 46 : aaaaccctta agctaagcaa atttcaaagc aattcaaaaa ccctagcctc tctctcttta 60 tctctcacaa caaaatcttt gaaatggcga tctctaaggc ttccattgtt gttctcatga 120 tggtgattat ctccgtcgtt gcatcggcac agtctgaggc accagcacca agtcctactt 180 ctggatctag teg
(2) INFORMATION FOR SEQ ID NO: 47: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 39 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..39
(D) OTHER INFORMATION: / Ceres Seq. ID 1014076 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 47: Lys Thr Leu Lys Leu Ser Lys Phe Gin Ser Asn Ser Lys Thr Leu Ala 1 5 10 15 Ser Leu Ser Leu Ser Leu Thr Thr Lys Ser Leu Lys Trp A.rg Ser Leu
2C 25 3 J
A.rg Leu Pro Leu Leu Phe Ser
35 .2 INFORMATION FOR SEQ ID NO : 48 : H SEQUENCE CHARACTERISTICS:
(A) LENGTH: 36 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..36
(D) OTHER INFORMATION: / Ceres Seq. ID 1014077 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 48:
Met Ala He Ser Lys Ala Ser He Val Val Leu Met Met Val He He
5 10 15
Ser Val Val A.la Ser Ala Gin Ser Glu Ala Pro Ala Pro Ser Pro Thr 20 25 30 Ser Gly Ser Ser 35 (2) INFORMATION FOR SEQ ID NO: 49: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 711 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..711
(D) OTHER INFORMATION: / Ceres Seq. ID 1015865 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 49: actcttccgg tcaccgacta attctggtta gctcacattc cttatgctca ttcatccaca 60 gttccctaat taacgctacg aattttgttt ctcctcttat ttcttctttc ctcttgtaga 120 ataaggttta tcaaaagaat aagaataagg tttatctctt aaatctccga taattagcag 180 agttttttca ggattgagtt tgatttgctg ttttggaatc ataaattttg cgttttagtg 240 gataaaaagc tagcttaaag agttattgca gagaaaaaaa atgggatcga gagggattat 300 caacgataag tggtcaatga ggattctatg gggttgtgct atcggaagtg ctattggttt 360 atacatggtt gctgtagaga gacaaactca gaacagggct cgtgctatgg ctgagagttt 420 gagagctgct gaatcacaag gtgatggtga taatgtctaa tatctaccaa gtagtgctca 480 gttgaatact ctcagttgag tttttttttt tggtgtttgt ttttgttata atgacttctt 540 ctgccaagat ggtgttgatg tagtttcttt tttgcaaata atcgtaataa ggtttcgaaa 600 cttggagagt tgaagttgct gaacatacga tttgtgttat cgcaaaaaaa gttatttctt 660 atgcctgtca tgctatgttt gtgaattcga tttttaatgc gtattttcag c (2) INFORMATION FOR SEQ ID NO: 50: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59
( D ) OTHER INFORMAT ION : / Ceres Seq . I D 1015866 ' xi ) SEQUENCE DESCRI PT ION : SEQ I D NO : 50 :
Met Gl y Ser Arg Gly He H e A.sn A.sp Lys T rp Se r Met Arg H e Leu
1 10 15
Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr Met Val Ala Val
20 25 30 Liu . .--rr GGiinn T Thhrr GGiinn AA..ssnn AArrqq A Allaa A Arrgg AAlla Met Ala Glu Ser Leu Arg
35 .0 45
A.la A..a Glu Ser Gin Gly _-.sp Gly A.sp As
50 55
(2) INFORMATION FOP SEQ ID NO: 51: H) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 47 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 1015867 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:51:
Met A.rg He Leu Trp Gly Cys Ala He Gly Ser A.la He Gly Leu Tyr 1 5 10 15
Met /al Ala Val Glu Arg Gin Thr Gin Asn Arg Ala Arg Ala Met A.la 20 25 30 Glu Ser Leu A.rg Ala Ala Glu Ser Gin Gly Asp Gly Asp Asn Val 35 40 45
(2) INFORMATION FOR SEQ ID NO: 52: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 38 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..38
(D) OTHER INFORMATION: / Ceres Seq. ID 1015868 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 52: Ser Ser Gly His Arg Leu He Leu Val Ser Ser His Ser Leu Cys Ser 1 5 10 15
Phe He His Ser Ser Leu He A.sn Ala Thr Asn Phe Val Ser Pro Leu
20 25 30
He Ser Ser Phe Leu Leu 35 (2) INFORMATION FOR SEQ ID NO:53: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 432 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..432
(D) OTHER INFORMATION: / Ceres Seq. ID 1021371 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 53: gtcattttct cgattctcac tcttccggtc accgactaat tctgagaaaa aaaatgggat 60 egagagggat tatcaacgat aagtggtcaa tgaggattct atggggttgt gctatcggaa 120 gtgctattgg tttatacatg gttgctgtag agagacaaac tcagaacagg gctcgtgcta 180 tggctgagag tttgagagct gctgaatcac aaggtgatgg tgataatgte taatatctac 240 caagtagtgc tcagttgaat actctcagtt gagttttttt ttttggtgtt tgtttttgtt 300 ataatgactt cttctgccaa gatggtgttg atgtagtttc ttttttgcaa ataatcgtaa 360 taaggtttcg aaacttggag agttgaagtt gctgaacata cgatttgtgt ^atcgcaaaa 420 aaagttattt cc
(2) INFORMATION FOR SEQ ID NO: 54: (ι) SEQUENCE CHARACTERISTICS: LENGTH: 76 ammo aciαs
(3 TYPE: ammo acid C) STRANDEDNESS: (D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
Α) NAME/KEY: peptide (B) LOCATION: 1..76
(D) OTHER INFORMATION: / Ceres Seq. ID 1021372 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 54: His Phe Leu Asp Ser His Ser Ser Gly His Arg Leu He Leu Arg Lys 1 5 10 15
Lys Met Gly Ser Arg Gly He He Asn Asp Lys Trp Ser Met A.rg He
20 25 30
Leu Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr Met Val Ala 35 40 45
Val Glu Arg Gin Thr Gin Asn Arg Ala Arg Ala Met Ala Glu Ser Leu
50 55 60
Arg Ala Ala Glu Ser Gin Gly Asp Gly Asp Asn Val 65 70 " 75 (2) INFORMATION FOR SEQ ID NO:55: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 59 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59 (D) OTHER INFORMATION: / Ceres Seq. ID 1021373
(xi) SEQUENCE DESCRIPTION: SEQ ID NO:55: Met Gly Ser Arg Gly He He Asn Asp Lys Trp Ser Met Arg He Leu 1 5 10 15
Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr Met Val Ala Val 20 25 30
Glu Arg Gin Thr Gin Asn Arg Ala Arg Ala Met Ala Glu Ser Leu Arg
35 40 45
Ala Ala Glu Ser Gin Gly Asp Gly Asp Asn Val 50 55 (2) INFORMATION FOR SEQ ID NO: 56: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 47 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 1021374 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 56: Met A.rg He Leu Trp Gly Cys Ala He Gly Ser Ala He Gly Leu Tyr 1 5 ' 10 15
Met Val Ala Val Glu A.rg Gin Thr Gin Asn A.rg A.la Arg A.la Met Ala
20 25 30
Glu Ser Leu Arg Ala Ala Glu Ser Gin Glv Asp Gly Asp Asn Val 35 40 " 45
.2} INFORMATION FOR SEQ ID NO:57: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 286 base pairs (B^ TYPE: nucleic acid C STRANDEDNESS: single
1, TOPOLOGY: linear ι_; MOLECULE TYPE: DNA (genomic; (ix) FEATURE:
.A) NAME/KEY: - (B) LOCATION: 1..286
(D) OTHER INFORMATION: / Ceres Seq. ID 1022578 ,xι) SEQUENCE DESCRIPTION: SEQ ID NO: 57: eaccattgga tggttcggct atacaagctg aaacctccca ggaacaggat tcgtggtaaa 60 gcaaagaaac tgaaatcgaa aacaagctct ggattgagtt caaaatcagc gaagaagaac 120 ccgtgggtct agaaatccta gaattttcaa tgttggatgg tgagttatat gtcaactctt 180 aggtctcttt attatcgaga aagttgttgc agacgcagtc aagtttctgg tgtaggattc 240 gtaaaaattt tgttaacttt attcgaattt catgtttatt gcggag (2) INFORMATION FOR SEQ ID NO: 58: 'i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 43 amino aciαs
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear 'ii' MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..43
(D) OTHER INFORMATION: / Ceres Seq. ID 1022579 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 58: His His Trp Met Val Arg Leu Tyr Lys Leu Lys Pro Pro Arg Asn Arg 1 5 10 15
He Arg Gly Lys Ala Lys Lys Leu Lys Ser Lys Thr Ser Ser Gly Leu
20 25 30
Ser Ser Lys Ser Ala Lys Lys Asn Pro Trp Val 35 40
(2) INFORMATION FOR SEQ ID NO: 59: (1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 43 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A.) NAME/KEY: peptide (B) LOCATION: 1..43
(D) OTHER INFORMATION: / Ceres Seq. ID 1022580 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 59: Met Val Ser Tyr Met Ser Thr Leu Arg Ser Leu Tyr Tyr Arg Glu Ser 1 5 10 15
Cys Cys Arg Arg Ser Gin Val Ser Gly Val Gly Phe Val Lys He Leu 2θ' 25 30 Leu Thr Leu Phe Glu Phe His Val Tyr Cys Gly 35 40
(2) INFORMATION FOR SEQ ID NO: 60: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 40 amino acids (B) TYPE: amino acid
(C; STRANDEDNESS: (D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..40
(D OTHER INFORMATION: / Ceres Seq. ID 1022581 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 60: Met ".'al Arq Leu Tyr Lys Leu Lys Pro Pro Ar zs Asn Arc. He Arq Gly 1 5" 10 " 15' "
Lys A.la Lys Lys Leu Lys Ser Lys Thr Ser Ser Gly Leu ≤er Ser Lys
20 25 20
Ser Ala Lys Lys A.sn Pro Trp Val 35 40 (2) INFORMATION FOR SEQ ID NO: 61: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 643 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..643 (D) OTHER INFORMATION: / Ceres Seq. ID 1024240
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 61: agactcagtg aggattttct aggcgatttt ctcgagaaaa tegtttgagg aaaatggaga 60 cttctatgag gtataccagc aattccaagt ctatgaagat teatgecaaa gagaaggttc 120 cggtgaactc aaaaacccat ttacagcttc atggagagtt agatactgga actggggctc 180 cgagttactt ctgtgcgatg attagacact tttttcctga ggccttgggg taggattgca 240 ttatgataag cgccaaaagc ttcggtgtct tgtacgcgga aaaaaagagt ttcctgtaag 300 agctgataag cgtgtaacct ttaatattaa agggcggtgt gatattgatc aggacttaaa 360 tcagaagaae cccaaaggag cagcagaatt tgcctggaac ataatggatt tcaaggaaga 420 tcaggatgta cggatcaaag ttggctacga aatgtttgat aaggtccctt atatgcagat 480 tagagaaaac aattggactc tcaacgcgaa catgaaggga aaatggaact tgcggtatga 540 cctgtaactg catttttttc aatcatcate tgagaaatgt attgatacca ctgctgatga 600 acacatttta attctaccaa ttaatcaaat tcagagatct tec (2) INFORMATION FOR SEQ ID NO: 62: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 59 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 1024241 . i) SEQUENCE DESCRIPTION: SEQ ID NO: 62: Met Giu Thr Ser Met Arg Tyr Thr Ser Asn Ser Lys Ser Met Lys He 1 5 " 10 " 15
His Ala Lys Glu Lys Val Pro Val Asn Ser Lys Thr His Leu Gin Leu 20 25 30
His Gly Glu Leu Asp Thr Gly Thr Gly Ala Pro Ser Tyr Phe Cys Ala
35 40 45
Met He Arg His Phe Phe Pro Glu Ala Leu Gly 50 55
(2) INFORMATION FOR SEQ ID NO: 63: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 55 amino acids
(B) TYPE: ammo acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..55
(D) OTHER INFORMATION: / Ceres Seq. ID 1024242 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 63:
Met Arg Tyr Thr Ser A.sn Ser Lys Ser Met Lys He His Ala Lys Glu
1 5 10 15 L LyysS '. aall P Prroo VVaall A Assnn S Seerr L Lyyss TThhrr H Hiiss L Leeuu Gin Leu His Gly Glu Leu 20 __5 30 π.Sp Tor Gly Thr Gly Aia Pro Ser T:r Phe s A.la Met He Arg His 25 40 45
Phe Phe Pro Glu Ala Leu Gly 50 55
(2) INFORMATION FOR SEQ ID NO:64:
(1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 47 ammo acids
(B) TYPE: ammo acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 1024243 'xi) SEQUENCE DESCRIPTION: SEQ ID NO: 64: Met A.sp Phe Lys Glu A.sp Gin Asp Val A.rg He Lys Val Gly Tyr Glu 1 5 10 15 Met Phe Asp Lys Val Pro Tyr Met Gin He Arg Glu Asn Asn Trp Thr
20 25 30
Leu Asn Ala Asn Met Lys Gly Lys Trp Asn Leu Arg Tyr Asp Leu
35 40 45
(2) INFORMATION FOR SEQ ID NO: 65: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 729 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..729
(D) OTHER INFORMATION: / Ceres Seq. ID 1026562 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 65: gttaatcata taaatttgac cctaaaatct atctcattct ctcatcaatc ttcttccttt 60 aaatccctaa atcttcacgt tacttttcta tctacatttt cactttcaat ggctttgatt 120 atcacctgct ccgctctacc cacgatccga gcatcttccg gatceggatc ccttaacccg 180 gatcaaaacc gtaagaaatc tgctqcttgg tgggctcctc tcttcggttt accctccgat 240 ccagattacc tcaacatcga aagctcatgc tccaccgtga atccggataa aaccgatatt 300 tccgggtcgg gtcaaaagtt tcgtcgcggt tgttttacgg aggagaaagc taagcagttg 360 aggaggaaaa ccgcagaagc ttccacgttc catgacgtaa tgtatcactc cgccattgct 420 tctcgacttg cgtctgatat caccggccga gtcgaggatt gaaacggatt cgggtcagat 480 ctggagacga atcaattaat gaataatgaa ttaatctttt ttttcttaat tcagtgttct 540 tgtaggatgc agaccatctt ctatcggtgc tcctttttca tttgaaccgt tggcttgtgt 600 ttggtctttg tgtgttgtaa actctggttc cctttctgtt tcttctgtaa tcaaccgttg 660 gatttccact tgttattttt agacatgtgt tccctagtta gctcttttat cttatctcaa 720 atttaaggc
(2) INFORMATION FOR SEQ ID NO: 66: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 153 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii; MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..153
(D) OTHER INFORMATION: , Ceres Seq. ID 1026563 (xi. SEQUENCE DESCRIPTION: SEQ IC NO: 66: Val A.sn His He Asn Leu Thr Leu Lys Ser He Ser Phe Ser His Gin 1 _ 10 15
Ser Ser Ser Phe Lys Ser Leu A.sn Leu His '/al Thr Phe Leu Ser Thr
20 25 30
Pne Ser Leu Ser Met A.la Leu He He Thr Cys Ser Ala Leu Pro Thr 35 40 45 He Arg Ala Ser Ser Gly Ser Gly Ser Leu A.sn Pro Asp Gin Asn Arg 50 55 60
Lys Lys Ser Ala Ala Trp Trp Ala Pro Leu Phe Gly Leu Pre Ser A.sp 65 70 75 80
Pro Asp Tyr Leu Asn He Glu Ser Ser Cys Ser Thr Val Asn Pro Asp 85 90 95
Lys Thr A.sp He Ser Gly Ser Gly Gin Lys Phe Arg Arg Gly Cys Phe
100 105 ' 110
Thr Glu Glu Lys Ala Lys Gin Leu A-g Arg Lys Thr Ala Glu Ala Ser 115 120 125 Thr Phe His Asp Val Met Tyr His Ser Ala He Ala Ser Arg Leu Ala 130 135 140
Ser Asp He Thr Gly Arg Val Glu Asp 145 " 150
(2) INFORMATION FOR SEQ ID NO: 67: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 117 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..117
(D) OTHER INFORMATION: / Ceres Seq. ID 1026564 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 67:
Met Ala Leu He He Thr Cys Ser Ala Leu Pro Thr He Arg Ala Ser 1 5 10 15
Ser Gly Ser Gly Ser Leu Asn Pro A.sp Gin Asn Arg Lys Lys Ser Ala 20 25 30 Ala Trp Trp Ala Pro Leu Phe Gly Leu Pro Ser Asp Pro Asp Tyr Leu 35 40 45
Asn He Glu Ser Ser Cys Ser Thr Val Asn Pro Asp Lys Thr Asp He
50 55 60
Ser Gly Ser Gly Gin Lys Phe Arg Arg Gly Cys Phe Thr Glu Glu Lys 65 70 75 80
Ala Lys Gin Leu Arg Arg Lys Thr Ala Glu Ala Ser Thr Phe His Asp 85 90 95 Val Met Tyr His Ser Ala He Ala Ser Arg Leu Ala Ser Asp He Thr
100 105 110
Gly Arg Val Glu Asp 115 (2) INFORMATION FOR SEQ ID NO: 68: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 484 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
*ιi) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..484 (D) OTHER INFORMATION: / Ceres Seq. ID 1026648
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 68: aaggatcaca aaattagggt tttaatttga tagagaagat gaatttcaga agctttgagg 60 agttctggcc tttctacatg atgcaacact cgaatccatc gacgcgaagg ttgcacttca 120 aggtatcat cgcgagcatc gttgctttga tatgttcqat tttgatcaac tggtggttct 180 taqctctggt gcctctqctt gggtacggat tcgcgtggta tagccacttc ttcgtggaag 240 ggaatgttcc ggcgagcttt gggcacccgc tttggtcgtt tctctgcgat ctcaagatgt 300 ttagtetgat gctcacagga agcatggaga gagagatgaa gagacttggt aagaggccat 360 gttgcagct ctcttgaagc agcagcagat atctctatag aattgttctt gattcttctt 420 attgcgttct gcgattggat tttagactcc agtttgtaat tacttcatgg aatcgttgtt 480 tgcg
(2) INFORMATION FOR SEQ ID NO: 69: Η SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 112 ammo acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..112
(D) OTHER INFORMATION: / Ceres Seq. ID 1026649 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 69: Met A.sn Phe A.rg Ser Phe Glu Glu Phe Trp Pro Phe Tyr Met Met Gin 1 5 10 15 His Ser Asn Pro Ser Thr Arg Arg Leu His Phe He Gly He He Ala
20 25 30
Ser He Val Ala Leu He Cys Ser He Leu He Asn Trp Trp Phe Leu
35 40 45
Ala Leu Val Pro Leu Leu Gly Tyr Gly Phe Ala Trp Tyr Ser His Phe 50 55 60
Phe Val Glu Gly Asn Val Pro Ala Ser Phe Gly His Pro Leu Trp Ser 65 70 75 80
Phe Leu Cys Asp Leu Lys Met Phe Ser Leu Met Leu Thr Gly Ser Met 85 90 95 Glu Arg Glu Met Lys Arg Leu Gly Lys Arg Pro Leu Leu Gin Leu Ser
100 105 110
(2) INFORMATION FOR SEQ ID NO: 70: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 99 amino acids (B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..99
(D) OTHER INFORMATION: / Ceres Seq. ID 1026650 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 70: Met Met Gin His Ser Asn Pro Ser Thr Arg Arg Leu His Phe He Gly 1 5 10 15
He He Ala Ser He Val Ala Leu He Cys Ser He Leu He Asn Trp 20 25 30
Trp Phe Leu Ala Leu Val Pro Leu Leu Gly Tyr Gly Phe Ala Trp Tyr
35 40 45
Ser His Phe Phe Val Glu Gly Asn Val Pro Ala Ser Phe Gly His Pro 50 55 60 Leu Trp Ser Phe Leu Cys Asp Leu Lys Met Phe Ser Leu Met Leu Thr 65 70 75 80
Gly Ser Met Glu Arg Glu Met Lys Arg Leu Gly Lys Arg Pro Leu Leu
85 90 95
Gin Leu Ser
( 2 ) INFORMATION FOR SEQ ID NO: 71: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 98 ammo acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D; TOPOLOGY: linear ii) MOLECULE TYPE: peptide i ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..98
(D) OTHER INFORMATION: / Ceres Seq. ID 1026651 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:71: Met Gin His Ser Asn Pro Ser Thr Arg Arg Leu His Phe He Gly He 1 5 10 15 He Ala Ser He Val Ala Leu He Cys Ser He Leu He Asn Trp Trp 20 25 30
Phe Leu Ala Leu Val Pro Leu Leu Gly Tyr Gly Phe Ala Trp Tyr Ser
35 40 45
His Phe Phe Val Glu Giy Asn Val Pro Ala Ser Phe Gly His Pro Leu 50 55 60
Trp Ser Phe Leu Cys Asp Leu Lys Met Phe Ser Leu Met Leu Thr Gly 65 70 75 80
Ser Met Glu A.rg Glu Met Lys A.rg Leu Gly Lys A.rg Pro Leu Leu Gin 85 90 95 Leu Ser
(2) INFORMATION FOR SEQ ID NO: 72: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 563 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..563
(D) OTHER INFORMATION: / Ceres Seq. ID 1027881 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:72: aaaacacaga gagtgacgag agagagagag tgaaaatgga gaagtacttt ggaaatgcgt 60 acaggggaga tccaggagtg ccacatgcag atgcagatcg tttcatgaat atatggattg 120 gttctgctgc tttctccgtt cttacctggg ttaatcctta catgtggcag ctctctaacc 180 agttcaatta ccatgacaag tggatgctgt ttgagcagta ccactggaaa aaagcaaggg 240 caaagaagca accttatgaa ttcaagtgga ataagatacc caaagaagtc agggactcgt 300 actattacaa ctggccagtc tacttcccat agaagtgtct ctgtgttget gtgaatcaga 360 agagaaacca aacacttgtg gaacttctat ggaatctatc tctatctctt cttgatctgt 420 tattcgtagc acttttggat tttaagtttt ttcttttgta atgatcaatc tctcaactct 480 tcactgtttc atctcctcta gttgactctc ttatggaaat attgaatcte tttgaagagc 540 agaaccagaa tctgtctgtt atg ( 2 ) INFORMATION FOR SEQ I D NO : 73 : ( l ) SEQUENCE CHARACTERISTICS :
(A) LENGTH : 109 ammo acids ( B ) TYPE : amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..109
'D) OTHER INFORMATION: / Ceres Seq. ID 1027882 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:73: Asn Thr Glu Ser Asp Glu Arg Glu Arg Val Lγs Met Glu Lys Tyr Phe 1 5 10 15
Gly Asn Ala Tyr Arg Gly Asp Pro Gly Val Pro His A.la A.sp Ala Asp
20 25 30
Arg Phe Met A.sn He Trp He Gly Ser Ala Ala Phe Ser Val Leu Thr 35 0 45 Trp al Asn Pro Tyr Met Trp Gin Leu Ser Asr Gin Phe Asn Tyr His 50 55 60
.-.sp Lys Trp Met Leu Phe Glu Gin Tyr His Trp Lys Lys Ala A.rq A.la 65 ""0 "^5 80
Lys Lys Gin Pro Tyr Glu Phe Lys Trp Asn Lys He Pro Lys Glu Val 85 90 95
A.rg Asp Ser Tyr Tyr Tyr Asn Trp Pro Val Tyr Phe Pro
100 105
(2) INFORMATION FOR SEQ ID NO: 74: (l) SEQUENCE CHARACTERISTICS: [A) LENGTH: 98 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptiαe (ix) FEATURE:
(A) NAME/KEY: peptide 'B) LOCATION: 1..98 vC) OTHER INFORMATION: / Ceres Seq. ID 1027883 (Xi) SEQUENCE DESCPIPTION: SEQ ID 1.0:74: Met Glu Lys Tyr Phe Gly Asn Ala Tyr Arg Gly Asp Pro Gly Val Pro 1 5 10 " 15
His Ala Asp Ala Asp Arg Phe Met Asn He Trp He Gly Ser A.la Ala
20 25 30
Phe Ser Val Leu Thr Trp Val Asn Pro Tyr Met Trp Gin Leu Ser Asn 35 40 45
Gin Phe Asn Tyr His Asp Lys Trp Met Leu Phe Glu Gin Tyr His Trp
50 55 60
Lys Lys Ala Arg Ala Lys Lys Gin Pro Tyr Glu Phe Lys Trp Asn Lys 65 70 75 80 He Pro Lys Glu Val Arg Asp Ser Tyr Tyr Tyr Asn Trp Pro Val Tyr
85 90 95
Phe Pro
(2) INFORMATION FOR SEQ ID NO:75: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 75 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..75
(D) OTHER INFORMATION: / Ceres Seq. ID 1027884 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 75: Met Asn He Trp He Gly Ser Ala Ala Phe Ser Val Leu Thr Trp Val 1 5 10 15
Asn Pro Tyr Met Trp Gin Leu Ser Asn Gin Phe A.sn Tyr His Asp Lys
20 25 30
Trp Met Leu Phe Glu Gin Tyr His Trp Lys Lys Ala Arg Ala Lys Lys 35 40 " 45 Gin Pro Tyr Glu Phe Lys Trp Asn Lys He Pro Lys Glu Val Arg Asp 50 55 60
Ser Tyr Tyr Tyr Asn Trp Pro Val Tyr Phe Pro o5 70 ^5
2) INFORMATION FOR SEQ ID NO:76: i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 305 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear ii' MOLECULE TYPE: DMA genomic
_x FEATUPE:
Α) MAME/KEY: - ^B) LOCATION: 1..305
(D) OTHER INFORMATION: / Ceres Seq. ID 138179"? xi1 SEQUENCE DESCRIPTION: SEQ ID NO: 76: gaggttttgg ttttgttgac tcagtgagga ttt ctagge gattttctcg agaaaatcgt 60 ttgaggaaaa tggagacttc tatgaggtat aecagcaatt ccaagtctat gaagattcat 120 gccaaagaga aggttccggt gaactcaaaa acccatttac agcttcatgg agagttagat 180 aetggaactg gggctccgag ttacttctgt gcgatgatta gacacttttt tcctgaggct 240 tcaacaqgec ttggggtagg attgcattat qataagcgcc aaaagcttcg gtgtcttgta 300 cgcgg
(2) INFORMATION FOR SEQ ID NO:77: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 78 ammo aciαs (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear .π) MOLECULE TYPE: peptiαe ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..78
(D) OTHER INFORMATION: / Ceres Seq. ID 1381798 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 77: Met Glu Thr Ser Met A.rg Tyr Thr Ser Asn Ser Lys Ser Met Lys He 1 5 10 15
His Ala Lys Glu Lys Val Pro Val Asn Ser Lys Thr His Leu Gin Leu
20 25 30
His Gly Glu Leu Asp Thr Gly Thr Gly A.la Pro Ser Tyr Phe Cys Ala 35 40 45 Met He Arg His Phe Phe Pro Glu Ala Ser Thr Gly Leu Gly Val Gly 50 55 6θ"
Leu His Tyr A.sp Lys Arg Gin Lys Leu A.rg Cys Leu Val A.rg 65 70 ~ 75
(2) INFORMATION FOR SEQ ID NO: 78: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 74 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..74
(D) OTHER INFORMATION: / Ceres Seq. ID 1381799 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 78: Met Arg Tyr Thr Ser Asn Ser Lys Ser Met Lys He His Ala Lys Glu 1 5 10 15
Lys Val Pro Val Asn Ser Lys Thr His Leu Gin Leu His Gly Glu Leu
20 25 30
Asp Thr Gly Thr Gly Ala Pro Ser Tyr Phe Cys Ala Met He Arg His 35 40 45 Phe Phe Pro Glu Ala Ser Thr Gly Leu Gly Val Gly Leu His Tyr Asp 50 55 60
Lys Arg Gin Lys Leu Arg Cys Leu Val Arg 65 70
(2) INFORMATION FOR SEQ ID NO: 79: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear 'ii) MOLECULE TYPE: peptide
.ix) FEATURE:
(A! NAME/KEY: peptide (B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1381800 'xi) SEQUENCE DESCRIPTION: SEQ ID NO : 79 :
Met Lys He His Ala Lys Glu Lys Val Pro Val Asn Ser Lys Thr His 1 5 10 15
Leu Gin Leu His Gly Glu Leu Asp Thr Gly Thr Gly Ala Pro Ser Tyr 20 25 30 Phe Cys Ala Met He Arg His Phe Phe Pro Glu Ala Ser Thr Gly Leu 35 40 45
Gly Val Gly Leu His Tyr Asp Lys Arg Cn Lys Leu Arg Cys Leu Val
50 55 60
Arg 65
(2) INFORMATION FOR SEQ ID NO: 80: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 840 base pairs (3) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..840
(D) OTHER INFORMATION: / Ceres Seq. ID 1442747
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 80: acacgaaacg attccgcttc tccgcttcct tcataaatat ctcactcatc gtcactacat 60 tgttctttca cacgcaattt tcatttctct cttaaccgta aacgaatctc tcttctcaaa 120 gttttatttt etctctgcga tggctcaaga agatgttact gctgttgcta ctaacggtgc 180 tggtccggtg gagacgcatc ttgtcttcac tgagttcaag cagatgttgc tcgttgaagc 240 tcaaaaggtc ggtgacgctg ttactttcta caaatctgct tttggtgcga tcgagtctgg 300 tcattctctt taccctaagc gtaacttgac caagagcttc ctcatgttct ctcttctgag 360 cttaatctcg ctggctcttc cttcgttgtt tgcgacgttt cctctctccc tggtttttct 420 actgcgaaat cggaaggttc gggagtgact tttcttctcg gaactaagga tgctgaagcc 480 gccgttgcga aagctgttga cgccggagct gtgaaagtgg aggttacgga ggcagaagtt 540 gaactgggat tcaaaggaaa agttacggat ecttttggtg tcacttggat cttcgcggag 600 aagaagaccg tgatcaccga cgagaacaaa gaggtttaga atctgtcgtc ggatctaatt 660 cttcgtcggt ttctgaacaa aaaaaaatta tctattatcc taggtttatg cttttatttt 720 gtcttttgtg gaatccggta atcagtaaac cggatcgagt aggctaatga ctttcggatt 780 ctaatttcac cccttttgac aaactctaat cttggtgaaa ttgcatatta atctcgggct 840
(2) INFORMATION FOR SEQ ID NO: 81: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 148 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
Hi) MOLECULE TYPE: peptide 'ix) FEATURE:
(A) NAME/KEY: peptide (c) LOCATION: 1..148 (D) OTHER INFORMATION: / Ceres Seq. ID 1442748
,xi) SEQUENCE DESCRIPTION: SEQ ID NO:81: His Giu Thr He Pro Leu Leu A.rg Phe Leu His Lys Tyr Leu Thr His 1 5 10 15
Arg His Tyr He Val Leu Ser His Ala He Phe He Ser Leu Leu Thr 20 25 30
Val Asn Glu Ser Leu Phe Ser Lys Phe Tyr Phe Leu Ser Ala Met Ala
35 40 45
Gin Glu Asp Val Thr Ala Val Ala Thr Asn Gly A.la Gly Pro Val Glu rl 55 60 Thr His Leu Val Phe Thr Glu Phe Lys Gin Met Leu Leu Val Giu Ala €5 70 ""5 80
Gin Lys Val Gly A.SP A.la Val Thr Phe Tyr Lys Ser A.la Phe Gly Ala
85 90 95
He Glu Ser Gly His Ser Leu Tyr Pro Lys A.rg Asn Leu Thr Lys Ser 100 105 ~ 110
Phe Leu Met Phe Ser Leu Leu Ser Leu He Ser Leu Ala Leu Pro Ser
115 120 125
Leu Phe Ala Thr Phe Pro Leu Ser Leu Val Phe Leu Leu Arg Asn Arg 130 135 140 Lys Val Arg Glu 145
(2) INFORMATION FOR SEQ ID NO: 82: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 102 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..102
(D) OTHER INFORMATION: / Ceres Seq. ID 1442749 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 82: Met Ala Gin Glu Asp Val Thr Ala Val Ala Thr Asn Gly Ala Gly Pro 1 5 10 15
Val Glu Thr His Leu Val Phe Thr Glu Phe Lys Gin Met Leu Leu Val
20 25 30
Glu Ala Gin Lys Val Gly Asp Ala Val Thr Phe Tyr Lys Ser Ala Phe 35 40 45 Gly Ala He Glu Ser Gly His Ser Leu Tyr Pro Lys A.rg Asn Leu Thr 50 55 60
Lys Ser Phe Leu Met Phe Ser Leu Leu Ser Leu He Ser Leu Ala Leu 65 70 75 80
Pro Ser Leu Phe Ala Thr Phe Pro Leu Ser Leu Val Phe Leu Leu Arg 85 90 95
A.sn Arg Lys Val Arg Glu
100 (2) INFORMATION FOR SEQ ID NO: 83: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 74 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..74 (D) OTHER INFORMATION: / Ceres Seq. ID 1442750
( xi ) SEQUENCE DESCRIPTION: SEQ ID NO: 83:
Met Leu Leu Val Glu Ala Gin Lys Val Gly Asp Ala Val Thr Phe Tyr
1 5 10 15
LLyyss SSeerr Ala Phe Gly Ala He Glu Ser Gly His Ser Leu Tyr Pro Lys 20 25 30
Arg Asn Leu Thr Lys Ser Phe Leu Met Phe Ser Leu Leu Ser Leu He
35 40 45
Ser Leu Ala Leu Pro Ser Leu Phe Ala Thr Phe Pro Leu Ser Leu Val 50 55 60
Phe Leu Leu Arg Asn Arg Lys Val Arg Glu 65 70
.2) INFORMATION FOR SEQ ID MO: 84: 1' SEQUENCE CHARACTERISTICS: A! LENGTH: 513 base pairs
.3 TYPE: nucleic acid C; STRANDEDNESS: single ,1) TOPOLOGY: linear ,iι; MOLECULE TYPE: DNA (genomic) 'ix; FEATURE:
(A.) NAME/KEY: - (B) LOCATION: 1..513
(D) OTHER INFORMATION: / Ceres Seq. ID 1459199 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 84: aacttggatc ttaacacaga gaagaagcac aatcggaaga aaggagaaga cgaagatgtc 60 gttggtatgg ctggaagcga tgttgcctct cggaatcatc ggtgggatgc tctgtatcat 120 gggcaattct cagtactaca tccacaaagc ttatcatggc cgtcctaagc aeatcggcca 180 cgatgaatgg gatgttgcta tggaaagacg cgacaagaaa gtcgtcgaga aagctgcagc 240 tccttcctca tgattcgctt tatctctttt gtgttcctca ggtgaccact tgtggtgaca 300 aataaagtgc attccagaag aagaagaagc tgggggatct agtactttca ttcccatttg 360 attttccttg gacatattaa agctttcaga aatcagacct caataacatt tggtttatca 420 atatttctct attcgtgata ttttgtatgc ttttaagttg catgatacac tgaactactc 480 tcttgctgtg tgagtgaata aatgaatatc tgc (2) INFORMATION FOR SEQ ID NO:85: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 83 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
Α) NAME/KEY: peptide (B) LOCATION: 1..83
(D) OTHER INFORMATION: / Ceres Seq. ID 1459200 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:85:
Thr Trp He Leu Thr Gin Arg A.rg Ser Thr He Gly Arg Lys Glu Lys 1 5 10 15
Thr Lys Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He 20 25 30 He Gly Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His 35 40 45
Lys Ala Tyr His Gly A.rg Pro Lys His He Gly His Asp Glu Trp Asp
50 55 60
Val Ala Met Glu Arg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala 65 70 ' " 75 80
Pro Ser Ser (2) INFORMATION FOR SEQ ID NO: 86: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 ammo acids (C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1459201 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 86: Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He He Gly 1 5 10 15 Gly Met Leu Cys He Met Gly A.sn Ser Gin Tyr Tyr He His Lys A.la 20 25 30
Tyr His Gly Arg Pro Lys His He Gly His A.sp Glu Trp Asp /al Ala
35 40 ' 45
Met Glu Arg Arg Asp L^ s Lvs Val .'al Glu Lys Ala Ala Ala Pro Ser [ U
Ser 65
,,2) INFORMATION FOP SEQ II HO: 87: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 57 ammo acids B ) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ,π) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..57
(D) OTHER INFORMATION: / Ceres Seq. ID 1459202 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 87: Met Leu Pro Leu Gly He He Gly Gly Met Leu Cys He Met Gly Asn 1 5 10 15
Ser Gin Tyr Tyr He His Lvs Ala Tyr His Gly Arq Pro Lys His He
20 25 30
Gly His Asp Glu Trp Asp Val Ala Met Glu Arg Arg Asp Lys Lys Val 35 40 45
Val Glu Lys Ala Ala Ala Pro Ser Ser
50 55
(2) INFORMATION FOR SEQ ID NO: 88: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1140 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1140
(D) OTHER INFORMATION: / Ceres Seq. ID 1565605 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 88: atgatttgtt tacatttttt cgtggtgttc ttgatttttt tctttgatca aaactagtag 60 aaattttcca atttcgtcct gccttgtgat tagtagtaga tattttggaa tttgattagt 120 aggtagaaga agatggggac gacgttagat gtatcaagag cagagctagc acttgtggta 180 atgtatttga acaaaαcaga ggcaagagat aagttatgca gagctataca gtatggttcc 240 aagttcttga gtggtggaca acctggtact gctcaaaatg ttgacaaatc tactagctta 300 gcaagaaaag tcttccgtct tttcaagttt gtgaatgact tgcatggtct tatcagtcct 360 gtgcctaaag gaactcctct tcctcttgtt ttacttggaa agtcgaagaa cgcactttta 420 tctacattct tgttcctgga tcaaattgtc tggcttggga gatcaggaat atataagaac 480 aaagaacgag ctgagttact tggacgtata tctctcttct gctggatggg atcttctgtc 540 tgcacaactt tagtcgaggt tggtgagatg ggaaggcttt cttcatcaat gaagaagatc 600 gaaaagggac tcaagaatgg aaacaagtat caggatgagg attatcgtgc taagctaaaa 660 aaatcaaacg agaggtcact tgctttgatc aaatcagcta tggacattgt tgtagcagct 720 ggtcttcttc agttagctcc aacgaagatc actcctcgtg tcaccggagc ttttggattc 780 atcacctcca tcatttcttg ttaccagttg cttccgacac gccccaagat caaaacaccc 840 tgaagtcaat cgaggaagct ggtgttaagg agaaagtcat ttcagaaagt ttctgttctt 900 cttattatta aggaaattca ctgctgttat aaaacatcgt ataaaatact tatttgcagg 960 aattacggtt attataaatt tatgcctcag attcttgata cacaagtttc aatactcaat 1020 agtattgcat tattatgaga tgttgtttct Gctacgcaat aactagaggc aaaatccaac 1080 tacatatatg ttttgatctg attattataa tagactttgg gcttcattcc gcctaaagct 1140 (2) INFORMATION FOR SEQ ID NO: 89:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 236 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D1 TOPOLOGY: linear
11) MOLECULE TYPE: peptide ix) FEATURE:
NAME /KEY: peptide LOCATION : 1..236 OTHER INFORMATION: / Ceres Seq. .565606
XI. SEQUENCE DESCRIPTION: SEQ ID NO: 89:
Met Gly Thr Thr Leu Asp Val Ser Arg Ala Glu Leu Ala Leu Val Val
1 5 10 15
Met Tyr Leu Asn Lys A.la Giu Ala A.rg A.sp Lys Leu Cys A.rg Ala He
20 25 30
Gin Tyr Gly Ser Lys Phe Leu Ser Gly Gly Gin Pro Gly Thr A a Gin 35 10 45
Asn Val A.sp Lys Ser Thr Ser Leu Ala Arg Lys Val Phe A.rg Leu Phe 50 55 60
Lys Phe Val Asn Asp Leu His Gly Leu He Ser Pro Val Pro Lys Gly 65 70 75 80
Thr Pro Leu Pro Leu Val Leu Leu Gly Lys Ser Lys Asn A.la Leu Leu
85 90 95
Ser Thr Phe Leu Phe Leu A.sp Gin He Val Trp Leu Gly Arg Ser Gly
100 105 110
He Tyr Lys A.sn Lys Glu A.rg Ala Glu Leu Leu Gly A.rg lie Ser Leu
115 120 125
Phe Cys Trp Met Gly Ser Ser Val Cvs Thr Thr Leu Val Glu /al Gly
130 135 140
Glu Met Gly Arg Leu Ser Ser Ser Met Lys Lys He Glu Lys Gly Leu
145 150 155 160
Lys Asn Gly Asn Lys Tyr Gin A.sp Glu Asp Tyr A.rg Ala Lys Leu Lys
165 170 175
Lys Ser A.sn Glu Arg Ser Leu Ala Leu He Lys Ser Ala Met A.sp He 180 185 190
Val Val Ala A.la Gly Leu Leu Gin Leu Ala Pro Thr Lys He Thr Pro
195 200 205
Arg Val Thr Gly A.la Phe Gly Phe He Thr Ser He He Ser Cys Tyr
210 215 220
Gin Leu Leu Pro Thr Arg Pro Lys He Lys Thr Pro
225 230 235
(2) INFORMATION FOR SEQ ID NO: 90: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 220 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..220
(D) OTHER INFORMATION: / Ceres Seq. ID 1565607 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 90: Met Tyr Leu Asn Lys Ala Glu Ala Arg Asp Lys Leu Cys Arg Ala He 1 5 10 15
Gin Tyr Gly Ser Lys Phe Leu Ser Gly Gly Gin Pro Gly Thr Ala Gin
20 25' 30
A.sn Val Asp Lys Ser Thr Ser Leu A a A.rg Lys Val Phe Arg Leu Phe 35 40 45 Lys Phe Val Asn Asp Leu His Gly Leu He Ser Pro Val Pro Lys Gly 50 55 60
Thr Pro Leu Pro Leu Val Leu Leu GI-/ Lys Ser Lys A.sn A.la Leu Leu 65 70 "75 80 Ser Thi Phe Leu Phe Leu Asp Gin He Trp Leu Gly Arg Ser Gly 35 90 95
_e T r Lys A.sn Lys Giu Arg A.la Gl Leu Leu Gly Arg He Ser Leu 100 110 fne cys Trp Met Gly Ser Ser . a i Cys Thr Thr Leu Val Glu Val Gly
115 120 125
Gly A.rg Leu Ser Ser Met Lys Lys He Glu Lys ... Leu 140 isn A.sn __.y 3 T' r_ Gin ΞO Gli A.sp Tyr A.rg A a Lys Leu Lys 150 155 160
Lvs Sei A.sn Glu Arg Ser Leu til 3. Leu He Lys Ser A.la Met Asp He 165 170 175
A.la Ala Gly Leu Leu Gin Leu A.la Pro Thr L s He Thr Pro 180 185 190
:o Val Thr Gly Ala Phe Gl Phe He Thr Ser He He Ser Cys Tyr
195 200 205 Gin Leu Leu Pro Thr Arg Pre Lys He Lys Thr Pro 210 215 220
(2) INFORMATION FOR SEQ ID NO: 91: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 533 base pairs (B) TYPE: nucleic aciα
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
Hi) MOLECULE TYPE: DMA (genomic) , ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..533
(D) OTHER INFORMATION: / Ceres Seq. ID 1566686 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 91: atgattggtg gtttcttcgc cgatgttaaa ttcaacagat cgagagagaa aaaactctct 60 ctccctcctc cgttcaccgt cgcgactcgg ctctacagta cattttgttg agcaatctcg 120 tatttagagg attccaatgt ctggcgcaga ggataataaa tcttcccatg ctcagctttc 180 gtcccaaatt tttcttgatc ttgtggattc ggtgatagct gatgtagcat ctgagtgtca 240 tcgggtagca cgactaggac ttgatcgtga tttggatata gtagaagaag agttgagatt 300 gtcagtggaa gcgcgtgcga agatcgctga tcctagcaac aacctcgaaa ccaacaccaa 360 atatgttgtt gatatatttg ggcagactca ccctcctgta gctagtgaag tgttcaattg 420 catgaactgt gggcgacaaa ttgttgcagg aaggtttgct cctcatctgg aaaaatgcat 480 gggaaaggga agaaaggctc gtgGccaagG actaccagaa gcacaacggc tgc (2) INFORMATION FOR SEQ ID NO: 92: (i) SEQUENCE CHARACTERISTICS: ( (AA)) LLEENNGGTTHH:: 113322 aammiinnoo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..132 (D) OTHER INFORMATION: / Ceres Seq. ID 1566687 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 92: Met Ser Gly Ala Glu Asp Asn Lys Ser Ser His Ala Gin Leu Ser Ser 1 5 10 15 Gin He Phe Leu Asp Leu Val Asp Ser Val He Ala Asp Val Ala Ser 20 25 30
Glu Cys His Arg Val Ala Arg Leu Gly Leu A.sp Arg Asp Leu Asp He
35 40 45 Val Glu Glu Glu Leu Arg Leu Ser Val Glu Ala Arg Ala Lys He Ala 50 55 60
A.sp Pro Ser A.sn A.sn Leu Glu Thr Asn Thr Lys Tyr Val Val Asp He 65 70 75 80
Phe Gly Gin Thr His Pro Pro Val Ala Ser Glu Val Phe A.sn Cys Met 85 90 95 Asn Cys Gly Arg Gin He Val Ala Gly A.rg Phe Ala Pro His Leu Glu
100 105 110 Lys Cys Met Gly Lys Gly Arg Lys Ala A.rq Gly Gin Glv Leu Pro Glu
115 120 125
Ala Gin Arq Leu 130
(2) INFORMATION FOR SEQ ID NO: 93: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 815 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..815
(D) OTHER INFORMATION: / Ceres Seq. ID 1567367 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 93: gaaacaagac acgaaagaat ctctaaagaa atcattttca tcgcttcgct tcgatttttc 60 ttcaatggct gtcgtcggcg ctccaatatc gtctccggcg gctcagctgc agacacaatt 120 tctctccaat cccattctcc cccgctttcg ccggtctttc tccaccggaa aatcaccagc 180 aactttctce gtcgtagcta tggctcceca gaaaaaggtg aacaaatatg atgccaagtg 240 gaagaaacaa tggtacggag ctggattgtt tttcgaaggg agtgagcaaa taaacgttga 300 tgttttcaag aagctggaga agcgaaaagt gttgagcaac gttgagaaat ctggcctgct 360 gtaaaagcag aggggttggg actcacattg tcatctcttg agaagcttaa agtcttctcc 420 aaagcagagg accttggtct tctcagtctc cttgagaact tagctggamG AAcatcgcct 480 gcggtcttag cctcggctgc attaccagct ctcacggctg ctattgtagc cgtggtgttg 540 atcccgaatg actcaactac tctagtggtt gctcaggcgg ttttggccgg tgctcttgcg 600 cttacagggg ttgttttgtt ggttggttct gttgttttgg atggacttca agaagctgac 660 tgattctttc tctgtaaacc aaacataaac ccatgtcttg tccaattgat ttttgtcagt 720 tgctgattta tagctgtatg gttcagttgt ttatggttag tccaagacat aagctgagtg 780 atagaaagaa gctttataat aattaaacaa atatt (2) INFORMATION FOR SEQ ID NO: 94: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 76 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..76
(D) OTHER INFORMATION: / Ceres Seq. ID 1567368 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 94: Glu Thr Arg His Glu Arg He Ser Lys Glu He He Phe He Ala Ser 1 ' 5 10 15
Leu Arg Phe Phe Phe Asn Gly Cys Arg Arg Arg Ser Asn He Val Ser 20 25 30 Gly Gly Ser Ala Ala Asp Thr He Ser Leu Gin Ser His Ser Pro Pro
35 40 45
Leu Ser Pro Val Phe Leu His Arg Lys He Thr Ser Asn Phe Leu Arg 50 55 60 Arg Ser Tyr Gly Ser Pro Glu Lys Gly Glu Gin He 65 70 75
(2) INFORMATION FOR SEQ ID NO: 95: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 120 amino acids (B) TYPE: amino acid
(C; STRANDEDNESS: (D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..120
(D) OTHER INFORMATION: / Ceres Seq. ID 1567369 ixi, SEQUENCE DESCRIPTION: SEQ ID NO:95: Lvs Gin Asp Thr Lvs Glu Ser Leu Lys Lvs Ser Phe ≤er Ser Leu Arq 5 " 1 15
Phe A.sp Pne Ser Ser Met Ala Val "al Gly Ala tro He Ser Ser Pro
20 25 30
A.la A.la Gin Leu Gin Thr Gin Phe Leu Ser A.sn Pro He Leu Pro A.rg 35 40 45 Phe Arg Arg Ser Phe Ser Thr Gly Lys Ser Pro A.la Thr Phe Ser Val 50 55 60
Val A.la Met A.la Pro Gin Lys Lys Val A.sn Lys Tyr Asp Ala Lys Trp 65 70 75 80*
Lys Lys Gin Trp Tyr Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu Gin 85 90 95
He A.sn Val Asp Val Phe Lys Lys Leu Glu Lys Arg Lys Val Leu Ser
100 105 110
Asn Val Glu Lys Ser Gly Leu Leu 115 120 (2) INFORMATION FOR SEQ ID NO: 96: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 99 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..99 (D) OTHER INFORMATION: / Ceres Seq. ID 1567370
(xi) SEQUENCE DESCRIPTION: SEQ ID MO: 96: Met Ala Val Val Gly Ala Pro He Ser Ser Pro Ala Ala Gin Leu Gin 1 5 10 15
Thr Gin Phe Leu Ser Asn Pro He Leu Pro Arg Phe Arg Arg Ser Phe 20 25 3θ'
Ser Thr Gly Lys Ser Pro Ala Thr Phe Ser Val Val Ala Met Ala Pro
35 40 45
Gin Lys Lys Val A.sn Lys Tyr Asp Ala Lys Trp Lys Lys Gin Trp Tyr 50 55 60 Gly Ala Gly Leu Phe Phe Glu Gly Ser Glu Gin He Asn Val Asp Val 65 70 75 80
Phe Lys Lys Leu Glu Lys Arg Lys Val Leu Ser Asn Val Glu Lys Ser
85 90 95
Gly Leu Leu
(2) INFORMATION FOR SEQ ID NO: 97: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 541 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
5 (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..541
(D) OTHER INFORMATION: / Ceres Seq. ID 1570101
10 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 97: aaaMctttac gttggtatta tctggtttca cattttctta accctctttg gtqaatgcgt 60 cattgaaacg ccattatccg ccgtgctaat ctgatctcct cccccgtcgg aaaaaatggc 120 cactggtgga aaagtctcct tcaaagtcac tctgacttcg gatcctaagc ttcc ttcaa 180 agttttcagc gtaccagaag gagctccgtt cacggcggtt ctgaaattcg cagcaqaaga 240
15 gttcaaggtt cctccacaaa ccagcgccat catcactaat gatgggatcg ggatcaatec 300 tcaacagagt gcaggaaacg tttttctgaa gcacggatct gaactaagat tgatccegeg 360 tgatagagtt ggagctgtgt ttgtgatgga tccatagatg atgtgtaagc aatgattaaa 420 aactcagttc caaaaaaaaa acataataat atactgaaat gcttatgtat caactTccrtt 480 gaataaatat gtaatcgtca catcctttta cqgattgaag tgagttqaat ttqgtcaaot 540 Z 9. ΩK 1e
2 . INFORMATION FOR SEQ ID MO: 98:
;ι> SEQUENCE CHARACTERISTICS:
(A) LENGTH: 93 amino acids 25 (C) STRANDEDNESS:
(D) TOPOLOGY: linear ■ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide 30 (B) LOCATION: 1..93
(D) OTHER INFORMATION: / Ceres Seq. ID 1570102 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 98: Met Ala Thr Gly Gly Lys Val Ser Phe Lys Val Thr Leu Thr Ser Asp 1 5 10 15
35 Pro Lys Leu Pro Phe Lys Val Phe Ser Val Pro Glu Gly Ala Pro Phe
20 25 30
Thr A.la Val Leu Lys Phe Ala A.la Glu Glu Phe Lys Val Pro Pre Gin
35 40 45
Thr Ser Ala He He Thr A.sn Asp Gly He Gly He Asn Pre Gin Gin 40 50 55 60
Ser A.la Gly Asn Val Phe Leu Lys His Gly Ser Glu Leu Arg Leu He 65 70 " 75 80
Pro Arg Asp Arg Val Gly Ala Val Phe Val Met Asp Pro 85 90
45 (2) INFORMATION FOR SEQ ID NO: 99: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 418 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single 50 (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..418
55 (D) OTHER INFORMATION: / Ceres Seq. ID 1571051
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 99: aaaaggaaga cgacgatgca gagtttaacg tcaaacgaag tTgegggttt ggcagttggg 60 gctctgcttc ttggtgccac catcgctgct cctaaagttg atgcttttat cgctgcttct 120 cagagaagat ctcttggcat gtgtcgaaaa tgtggagatc ttaagaatgt agcttgtggc 180
60 cgttgcaaag gaacaggaac aatcaaatca ggaggattct ttggtttcag tgactcatca 240 aacacaagat cagtggcttg cgataattgc caagccaaag gttgtttccc ttgccctgaa 300 tgctcaaaat cttgaccatt ttctcggtat tttatagttg tttcatcttc ttgacactat 360 gataagtgta atcggtccat tggtaatggt aatgttaaag ttgaagaatg tcttgttt (2) INFORMATION FOR SEQ ID NO: 100: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 104 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
( D) TOPOLOGY: linear ιi) MOLECULE TYPE: peptide ix) FEATURE: (A) NAME/KEY: peptide
\ 3 ) LOCATION: 1..104
(D) OTHER INFORMATION: / Ceres Seq. ID 1571052 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 100: Lys A.rg Lys Thr Thr Met Gin Ser Leu Thr Ser A.sn Giu Val A.la Gly 1 5 10 15
Leu A.ia Val Gly A.la Leu Leu Leu Gly Ala Thr He Ala Ala Pro Lys
20 25 30
Val A.sp Ala Pne He Ala Ala Ser Gin A.rg A.rg Ser Lei Gly Met Cys 35 40 -5 Arq Lys Cys GH Asp Leu L ,-s A.sn .al Ala 3 G__ Arq Cys Lys Gly
: Z j
Tr.r G_y Thr He Lys Ser Gly Gly Phe Phe Gly Pne ≤er A.sp Ser ≤er 65 70 ""5 80
Asn Tr.r Arg Ser ""al Ala Cys A.sp A.sn Cys Gin A.la . s Gly Cys Phe 85 90 95
Pro Cys Pro Glu Cys Ser Lys Ser
100 (2, INFORMATION FOR SEQ ID NO: 101: .1) SEQUENCE CHARACTERISTICS: (A) LENGTH: 99 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide 'ix) FEATURE:
.A) NAME/KEY: peptide B) LOCATION: 1..99
1, OTHER INFORMATION: / Ceres Seq. ID 1571053 ,xi) SEQUENCE DESCRIPTION: SEQ ID NO: 101: Met Gin Ser Leu Thr Ser Asn Giu Val Ala Gly Leu Ala Val Gly Ala 1 5 10 15
Leu Leu Leu Gly Ala Thr He Ala Ala Pro Lys Val Asp Ala Phe He
20 25 30
A.la Ala Ser Gin Arg Arg Ser Leu Gly Met Cys Arg Lys Cys Gly Asp 35 40 45
Leu Lys Asn Val A.la Cys Gly Arg Cys Lys Gly Thr Gly Thr He Lys
50 55 60
Ser Gly Gly Phe Phe Gly Phe Ser Asp Ser Ser Asn Thr Arg Ser Val 65 70 75 80 Ala Cys Asp Asn Cys Gin Ala Lys Gly Cys Phe Pro Cys Pro Glu Cys
85 90 95
Ser Lys Ser
(2) INFORMATION FOR SEQ ID NO: 102: (i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 58 amino acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..58
(D) OTHER INFORMATION: / Ceres Seq. ID 1571054 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 102: Met Cys Arg Lys Cys Gly Asp Leu Lys Asn Val Ala Cys Gly Arg Cys 1 5 10 15
Lys Gly Thr Gly Thr He Lys Ser Gly Gly Phe Phe Gly Phe Ser Asp
20 25 30
Ser Ser Asn Thr Arg Ser Val Ala Cys Asp Asn Cys Gin Ala Lys Gly 35 40 45 Cys Phe Pro Cys Pro Glu Cys Ser Lys Ser 50 55
(2) INFORMATION FOR SEQ ID NO: 103: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 444 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: ..A) NAME/KEY: -
(B) LOCATION: 1..444
(D) OTHER INFORMATION: / Ceres Seq. ID 1571100 .Xi) SEQUENCE DESCRIPTION: SEQ ID NO:103 aatctacttt tgagttctct ggagcagctt tggtcttttc tctcttcagt tacagctcgc 60 gatccagatc catatccagt catggcgggt gtagtagcaa gaattgtgga aaagtttggt 120 aaacgtgata tttggtatcg aatatcgttg atatcaattc cagtctctag tgtcctaata 180 gtactaggga atatggagct tgctcgtatc agagaggaga agaagctttt gaaggagagg 240 tttgatcaae tgagggctag aggaataatc agagatcagt aatccaaaag tgtgtttagg 300 ctttgttttt ttgtttcttt tctatgaatt taatttttta tttctccttt ccatgaatta 360 accaactcta tgtaacgaga tgatttattc ttgtctctct aagactcgag atgattcgct 420 attgataaaa cttctattat tScc (2) INFORMATION FOR SEQ ID NO: 104- (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 93 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix; FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..93
(D) OTHER INFORMATION: / Ceres Seq. ID 1571101 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 104: Asn Leu Leu Leu Ser Ser Leu Glu Gin Leu Trp Ser Phe Leu Ser Ser 1 5 10 15
Val Thr Ala Arg Asp Pro Asp Pro Tyr Pro Val Met Ala Gly Val Val
20 25 30
Ala Arg He Val Glu Lys Phe Gly Lys Arg Asp He Trp Tyr Arg He 35 40 45 Ser Leu He Ser He Pro Val Ser Ser Val Leu He Val Leu Gly Asn 50 55 60
Met Glu Leu Ala Arg He Arg Glu Glu Lys Lys Leu Leu Lys Glu Arg 65 70 75 80~
Phe Asp Gin Leu Arg Ala Arg Gly He He Arg Asp Gin 85' 90
(2) INFORMATION FOR SEQ ID NO: 105: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 66 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide ( ix ) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..66
(D) OTHER INFORMATION: / Ceres Seq. ID 1571102 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 105:
Met Ala Gly Val Val Ala Arg He Val Glu Lys Phe Gly Lys Arg Asp 1 5 10 15
He Trp Tyr A.rg He Ser Leu He Ser He Pro Val Ser Ser Val Leu 20 25 30 He Val Leu Gly Asn Met Glu Leu Ala Arg He Arg Glu Glu Lys Lys 35 40 45
Leu Leu Lys Glu Arg Phe A.sp Gin Leu Arg Ala Arg Gly He He A.rg
50 55 60
Asp Gin 65
(2) INFORMATION FOR SEQ ID NO: 106: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 636 base pairs
(B) TYPE: nucleic acid ) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA. (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..636
(D) OTHER INFORMATION: / Ceres Seq. ID 1665272 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 106: cagaataaaa atctatttct tgtgtttgtg ttatatttac ttaaaaaaat aaaggagatc 60 agtttgggag aaagcagcaa agaagaaaaa tggcagcaac atttgcaaca ccatcgacgg 120 tgataggcct cggaggatca tccatcacca ccaaaccctt ctcttcatcc tttttaaaac 180 caacattaag cgccaagaac cctttgagac tcgccggtgc atcgggagga agagtcactt 240 gctttgagag gaactggttg aggagagatt tgaacgtggt aggatttggg ctgatcggat 300 ggctagctcc gtcgagcatt ccagcgataa atgggaagag cctgacgggt ctcttcttcg 360 atagcatcgg aactgagctc gctcacttcc cgactcctcc agctctcact tcacagttct 420 ggttgtggtt ggttacgtgg cacttaggcc tcttcctctg cctcactttc ggacaaatcg 480 gattcaaggg caggactgag gattacttct aaggataact attcttgttt tcgtttgtac 540 tatatgctct ctcttggtta tgtgtaatat tatcaatcaa aacaaagctt tctttgctat 600 ttgatgtttc attctatatc tcgacaAgtc tttctt (2) INFORMATION FOR SEQ ID NO: 107: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 140 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..140
(D) OTHER INFORMATION: / Ceres Seq. ID 1665273 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 107:
Met Ala Ala Thr Phe Ala Thr Pro Ser Thr Val He Gly Leu Gly Gly 1 5 10 15
Ser Ser He Thr Thr Lys Pro Phe Ser Ser Ser Phe Leu Lys Pro Thr 20 25 30 Leu Ser Ala Lys Asn Pro Leu Arg Leu Ala Gly Ala Ser Gly Gly Arg 35 40 45
Val Thr Cys Phe Glu Arg Asn Trp Leu Arg Arg Asp Leu Asn Val Val
50 55 60
Gly Phe Gly Leu He Gly Trp Leu Ala Pro Ser Ser He Pro Ala He 65~ 70 75 80
Asn Gly Lys Ser Leu Thr Gly Leu Phe Phe Asp Ser He Gly Thr Glu 85 90 95 Leu Ala His Phe Pro Thr Pro Pro Ala Leu Thr Ser Gin Phe Trp Leu
100 105 110
Trp Leu Val Thr Trp His Leu Gly Leu Phe Leu Cys Leu Thr Phe Gly 115 120 125 Gin He Gly Phe Lys Gly Arg Thr Glu Asp Tyr Phe 130 135 140
(2) INFORMATION FOR SEQ ID NO: 108: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 522 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix; FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..522
(D) OTHER INFORMATION: / Ceres Seq. ID 1713895 (xi; SEQUENCE DESCRIPTION: SEQ ID NO: 108: aaacttggat cttaacacag agaagaagca caatcggaag aaaggagaag acgaagatgt 60 egttggtatg gctggaagcg atgttgccte tcggaatcat cggtgggatg ctctgtatca 120 tgggcaattc tcagtactac atccacaaag cttatcatgg ccgtcctaag cacatcggcc 180 acgatgaatg ggatgttgct atggaaagac gcgacaagaa agtcgtcgag aaagetgcag 240 ctccttcctc atgattcgct ttatctcttt tgtgttcctc aggggcttaa ggtgaccact 300 tgtggtgaca aataaagtgc attccagaag aagaagaagc tgggggatct agtactttca 360 ttcccatttg attttccttg gacatattaa agctttcaga aatcagacct caataacatt 420 tggtttatca atatttctct attcgtgata ttttgtatgc ttttaagttg catgatacac 480 tgaactactc tcttgctgtg tgagtgaata aatgaatatc tg (2) INFORMATION FOR SEQ ID NO: 109: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 83 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..83
(D) OTHER INFORMATION: / Ceres Seq. ID 1713896 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 109: Thr Trp He Leu Thr Gin Arg Arg Ser Thr He Gly Arg Lys Glu Lys 1 5 10 15
Thr Lys Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He
20 25 30
He Gly Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His " 35 40 45
Lys Ala Tyr His Gly Arg Pro Lys His He Gly His Asp Glu Trp Asp
50 55 60
Val Ala Met Glu Arg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala 65 70 75 80 Pro Ser Ser
(2) INFORMATION FOR SEQ ID NO: 110: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 65 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..65
(D) OTHER INFORMATION: / Ceres Seq. ID 1713897 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 110: Met Ser Leu Val Trp Leu Glu Ala Met Leu Pro Leu Gly He He Gly 1 5 10 15
Gly Met Leu Cys He Met Gly Asn Ser Gin Tyr Tyr He His Lys Ala 20 25 30
Tyr His Gly Arg Pro Lys His He Gly His Asp Glu Trp Asp Val Ala
35 40 45
Met Glu A.rg Arg Asp Lys Lys Val Val Glu Lys Ala Ala Ala Pro Ser 50 55 60 Ser 65
'2) INFORMATION FOR SEQ ID NO: 111: (ι) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 57 ammo acids
( 2 , STRANDEDNESS: .D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide i ix) FEATURE: Α) NAME/KEY: peptide
3) LOCATION: 1..3"
D) OTHER INFORMATION: / Ceres Seq. ID 1713898 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 111: Met Leu Pro Leu Gly He He Gly Gly Met Leu Cys He Met Gly Asn 1 5 10 ' 15
Ser Gin Tyr Tyr He His Lys Ala Tyr His Gly Arg Pro Lys His He
20 25 30
Gly His A.sp Glu Trp Asp Val Ala Met Glu Arq A.rg A.sp Lys Lys Val 35 40 45 Val Glu Lys Ala Ala Ala Pro Ser Ser 50 55
(2) INFORMATION FOR SEQ ID NO: 112: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 745 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..745
(D) OTHER INFORMATION: / Ceres Seq. ID 1923752 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 112: acgcttagga tttaaggact atcgttcttg gttgtggatt ctcgcccacc gtcttgctta 60 cgagtcacac accaccgtcc ttggatcgag tcttcaactt aagctctgat gctaattcac 120 atcaaagctg acttgctctg actttgtctc tcaaggattt gaggcgtgat tcaagaacaa 180 aacaaattaa agaacaactt ttetttattt atttagaaac tactcaaaac taaatctctc 240 taggtcttta gaacaactct ctaaagcctc tcaatctctt tcttgagact tatggaacaa 300 ctctccatag tctctctata tagaactgag ctacccctaa gtctatatct catgaagtct 360 ctctcgactc gcatgtttat ctcatgaggt ctctctcgac tctaaggaga tctctcttga 420 ctcacatctt gagctctctc tttgatcctc ttggatgctt tagctctctt gtgttatctt 480 cttcttcttc atagagatca tatatatact aggaccaaac acctcctttc cctattgtga 540 ataggaatac ttacaaatct tatccaactt gacattattt gtatttcttt ttttcttgat 600 ttcctttctt gaatttcttt tcctgtatct cttctagcat cttctagaag gagataactt 660 gctcctcaag taagttgtaa ttatccaaca cgcatgtgat ctttaatgat cgtggggatt 720 atttagtggc agagatgaat actct (2) INFORMATION FOR SEQ ID NO: 113: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 35 amino aciαs (B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..35 (D) OTHER INFORMATION: / Ceres Seq. ID 1923753
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 113: A.rg Leu Gly Phe Lys A.sp Tyr Arg Ser Trp Leu Trp He Leu Ala His 1 5 10 15
A.rg Leu Ala Tyr Glu Ser His Thr Thr Val Leu Gly Ser Ser Leu Gin 20 25 30
Leu Lys Leu
35 (2) INFORMATION FOR SEQ ID NO: 114: d) SEQUENCE CHARACTERISTICS: (A) LENGTH: 31 ammo acids
(B) TYPE: amino acid fC) STRANDEDNESS: (D, TOPOLOGY: linear iiil MOLECULE TYPE: peptide ix; FEATURE:
.A, NAME/KEi: peptiαe (B) LOCATION: 1..31
(D) OTHER INFORMATION: / Ceres Seq. ID 1923754 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 114: Met Glu Gin Leu Ser He Val Ser Leu Tyr Arg Thr Glu Leu Pro Leu 1 5 10 15
Ser Leu Tyr Leu Met Lys Ser Leu Ser Thr Arg Met Phe He Ser
20 25 30
(2) INFORMATION FOR SEQ ID NO: 115: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 36 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..36
(D) OTHER INFORMATION: / Ceres Seq. ID 1923755 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 115:
Met Arg Ser Leu Ser Thr Leu Arg Arg Ser Leu Leu Thr His He Leu 1 5 10 15
Ser Ser Leu Phe Asp Pro Leu Gly Cys Phe Ser Ser Leu Val Leu Ser 20 25 30 Ser Ser Ser Ser 35 (2) INFORMATION FOR SEQ ID NO: 116: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 487 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(n) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..487
(D) OTHER INFORMATION: / Ceres Seq. ID 1976816
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 116: aaaccctagc aaaaacctct ctctctctct caatteactt ctcctcctac aatggcttgg 60 cgcaacgcag gatctgctgc tcgttctttc gtctccgcca ccgcaagatc accatctctc 120 cgttctccca ccacggcgct tcctcgcctc cgtcctcctc aatcctcctt acctagccgt 180 cgcttcacct tctcgtcacc ttccaggaat ctaggagccc taggttgcac acagtcgttc 240 ttgcctctgt acagtgttgt ggctacttct caactgacat ctcaccttaa cgttaatttg 300 cgagctttct gcgagctgtc taacggtact tgaagaggca aaagagtgta atttcactgc 360 gcatgcgtga atcagtactt tgaagggatg tgagatcgaa attgtgggat tacctcagca 420 aaaacttgct taatgtgttg cctgttttag aagttttagt ttcacaatgt gtggatttat 480 tagttgt
(2) INFORMATION FOR SEQ ID NO: 117: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 70 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..70 (D) OTHER INFORMATION: / Ceres Seq . ID 197681")
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 117:
Asn Pro Ser Lys Asn Leu Ser Leu Ser Leu ftsn Ser Leu Leu Leu Leu 5 10 15 Gin Tro Leu GO A.la .hr Gin 'SD Leu Leu Leu Vai Leu Ser Ser Pro
20 25 Pro Pre Gin A.SP His His Leu Ser Val Leu Fro Pro Arg Arg Pne Leu
35 40 45 Ala Ser Val Leu Leu Asn Pro Pro Tvr Leu Ala Val Ala Ser Pro Ser
50 55 60
A.rg His Leu Pro Gly He 65 70
INFORMATION FOR SEQ ID NO: 118: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 57 ammo acids
(B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..57 (D) OTHER INFORMATION: / Ceres Seq ID 1976818
(xi! SEQUENCE DESCRIPTION: SEQ ID NO: 118:
Thr Leu Ala Lys Thr Ser Leu Ser Leu Ser He His Phe Ser Ser Tyr
1 5 10 15
Asn Gly Leu Ala Gin Arg Arg He Cys Cys Ser Phe Phe Arg Leu Arg
20 25 30
His Arg Lys He Thr He Ser Pro Phe Ser His His Gly Ala Ser Ser
35 40 45
Pro Pro Ser Ser Ser He Leu Leu Thr 50 55
(2) INFORMATION FOR SEQ ID : NO: 119:
(1) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 93 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: peptide (IX) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..93
(D) OTHER INFORMATION: / Ceres Seq. ID 1976819 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 119:
Met Ala Trp Arg Asn Ala Gly Ser Ala Ala Arg Ser Phe Val Ser Ala
1 5 10 15
Thr Ala Arg Ser Pro Ser Leu Arg Ser Pro Thr Thr Ala Leu Pro Arg 20 25 30
Leu Arg Pro Pro Gin Ser Ser Leu Pro Ser Arg Arg Phe Thr Phe Ser
35 40 45
Ser Pro Ser Arg Asn Leu Gly Ala Leu Gly Cys Thr Gin Ser Phe Leu 50 55 60
Pro Leu Tyr Ser Val Val Ala Thr Ser Gin Leu Thr Ser His Leu Asn 65 70 75 80
Val Asn Leu Arg Ala Phe Cys Glu Leu Ser Asn Gly Thr 85 90 (2) INFORMATION FOR SEQ ID NO: 120: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 566 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..566 (D) OTHER INFORMATION: / Ceres Seq. ID 2025128
'xi) SEQUENCE DESCRIPTION: SEQ ID NO: 120: atgaatcttc ttcgcttcgg ctccgcctct tattctcgag aaagctcatc ttgcttetca 60 catctaaaca aatatctcat ctcttctatt ctactttatc acttcatctc cgtacgctct 120 tctttcttcg ttgcttcttc ttttgattta taaattggat ccaaaacatc ataggctctc 180 gtcatcctta tatacaagca ttgttacttt gtgatataaa gaacgaagaa ttgtacgaag 240 gcaacgagca agatgagtag caaggcgaat gaggtttaaa agagtagcaa ggcgaatgaa 300 gttgaaagga ggaagatgaa tagcacggcc aatgacgatg aaaggatgaa taggatcatc 360 agagatggcc gtcgtcgtta cgtcacctgg agccgcagcc gcaacccctc ggcagctcat 420 atcttttggt caaaacccta atattttcta gggttgggct attagttttt gttttgggct 480 tttttgaatt gtattttggg ctttttatta atttgtagtg ggtaatttgt ttggattagg 540 atttttggta gtgtaatttt tttttt (2) INFORMATION FOR SEQ ID NO: 121: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 50 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..50
(D) OTHER INFORMATION: / Ceres Seq. ID 2025129 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 121: Met A.sn Leu Leu Arg Phe Gly Ser Ala Ser Tyr Ser Arg Glu Ser Ser 1 5 10 15
Ser Cys Phe Ser His Leu Asn Lys Tyr Leu He Ser Ser He Leu Leu
20 25 30
Tyr His Phe He Ser Val Arg Ser Ser Phe Phe Val Ala Ser Ser Phe 35 40 45 Asp Leu 50 (2) INFORMATION FOR SEQ ID NO: 122: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 47 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 2025130 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 122: Glu Ser Ser Ser Leu Arg Leu Arg Leu Leu Phe Ser Arg Lys Leu He 1 5 10 15
Leu Leu Leu Thr Ser Lys Gin He Ser His Leu Phe Tyr Ser Thr Leu 20 25 30
Ser Leu His Leu Arg Thr Leu Phe Phe Leu Arg Cys Phe Phe Phe
35 40 45
(2) INFORMATION FOR SEQ ID NO: 123: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 41 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii; MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAM IEE//KKEEYY:: ppeeppttiiddee
(B) LOC :AATTIIOONN:: 11....4411
(D) OTHER INFORMATION: / Ceres Seq. T .025131
(xi , SEQUENCE DESCRIPTION: SEQ ID MO: 123: Met A I..snj~. S Seerr TThhrr AAl.laa AA.ssnn AAsspp AA.sspp GGlluu AArrgg MMeett AAssnn A.rg He He A.rg
1 5 5 1100 15
A.sp G Gllyy AArrgg AArrgg AA..rrgg TTyyrr VVaall TThhrr TTrrpp SSeerr AA.rrcg SSeerr A.rg A.sn Pro Ser
20 25 30 A.la A Allaa H Hiiss HHee PPhhee TTrrpp SSeerr LLyyss PPrroo 35 40
INFORMATION FOR SEQ ID MO: 124:
! SEQUENCE CHARACTERISTICS:
(A) LENGTH: 545 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ϋ ) MOLECULE TYPE: DNA (genomic)
(ix ) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..545
(D) OTHER INFORMATION: / Ceres Seq. ID 2025402 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 124: tttttttttt ttttgcgaaa ttgaaatgat ctcacataaa aacteaattg ataattttac 60 aaaggagaaa aatttgtcaa tcaaagaaga agagaaagat tgaactttta acctcacttg 120 gtcataactt caacgccatt ctttccagcg ataatgacag aagtagccat tccgagaaac 180 agaccatgct ccaccactcc ttgaaactte ccaatctctt tagccgcagc gaatccatcc 240 ttcaaaggag tcttaaaata caaatcaata atgtaattac tgttatcagt cacataaggc 300 ttgccatcac catcaactct aagctttgat tcacateeaa attccttgaa gaggtcttgc 360 aatctaatca aattaaagtt ccagcagaat tgaacaactt ccaccggcat agctaatcca 420 cttccaccga gtcctgtaac gagtttggta tcatcagcca caacaataaa cttgtcagcc 480 acagcttcca ccattaccta gaacatccta atcgaaaaat tatccaatcc aatccattac 540 ttact
(2) INFORMATION FOR SEQ ID NO: 125: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 47 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..47
(D) OTHER INFORMATION: / Ceres Seq. ID 2025403 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 125: Met Leu His His Ser Leu Lys Leu Pro Asn Leu Phe Ser Arg Ser Glu 1 5 10 15
Ser He Leu Gin Arg Ser Leu Lys He Gin He Asn Asn Val He Thr 20 25 30
Val He Ser His He Arg Leu Ala He Thr He Asn Ser Lys Leu
35 40 45
(2) INFORMATION FOR SEQ ID NO: 126: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 33 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
,'D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..33
(D) OTHER INFORMATION: / Ceres Seq. ID 2025404 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:126:
Phe Phe Phe Phe Cys Glu He Glu Met He Ser His Lys Asn Ser He
1 5 10 15
A.sp Asn Phe Thr Lys Glu Lys A.sn Leu Ser He Lys Glu Glu Glu Lys 20 25 30
-.SD
2) INFORMATION FOR SEQ ID MO: 127: (i) SEQUENCE CHARACTERISTICS:
Α) LENGTH: 1954 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..1954
(D) OTHER INFORMATION: / Ceres Seq. ID 2025479 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 127: atggaacctt atataaccag aagagataca gttaatcaag tgttacatgc agaagaagaa 60 gaagaataca atgattgtga attggatcaa ctcttccttg tgcattctga tattagatct 120 gttcttctcc agattgatga gcttgttgtt gaagccacaa agcgtaagac cgtgagcaag 180 cacgggttaa tagaagttga atctttcaga actgtgttgt ctgatatgct ttcctcacta 240 aagccatggt ttcctcgatt gcaagaagcg atgtctgatt ttcagttgct tccagaggat 300 caggaagaac agtctttgat gagcacaaac gaagaagaag atttgtttga tgttgagagt 360 cctgagccta ctcaatttga gcccttagtc tctccttctc ctcttgtgca ttggcgtggt 420 gatcataacg cagacaaggg tagacaactc tttcttttga caccactacc cttaggaaaa 480 tctgaattcc taaaacacca gaatgcatct aagcttacag ctaaaaggat ttttccagac 540 actgttgcaa atgaaccgct tgaagcttct aaagaaacaa gtgatgatgt tttaggaggt 600 gagtcgttga aaactgcagg acttggtaaa tctttagtcc atgccatgga tttctctgaa 660 aatttggttg agtataagcc atgttcttca ecagttctca ggagaaagat tctgtctgag 720 cttctaatga caccttgctt gaagctgtcg cctccgaaat cgtgtacaat gtttaaaccg 780 gttcctgaat cttctcaact gggaaagcaa ggggcttgta agtctacctg ctctgaattg 840 ggatcatctg gtattgaaaa aacagacaat ctctgctcga agtatcctga gctcttggga 900 atacaacatg ctccgataac tagaaaaacg gatcttgaat cctcgccggt ttggtggttt 960 tctcctccta aaacatgtgt tttaatggag cctgtgaatg agaagaaacc aattgatgaa 1020 actggtggat cttttgatgt tccaaacatt ataccagaag caaaacacac tacagaggga 1080 agcatgtcaa tggtggttga gagtactcca ttgtttaaag aaccagagag cataatgacg 1140 agaaacagaa caaaagcagg tgagagtact ctgaagaaag agctatggac aagatttgaa 1200 gaagcaacga ttcatgacag tcggttcaac tcgatgacaa caacaacaac agtgagagga 1260 aataataaga aatgtttcat ggaaatgtta gaagaagtga gtggcaatga ggaagatcat 1320 gagttaagtg gcgagtttgt ggctctaaaa ccttatcaag tactcatatc ggaactgagc 1380 ataacaaacg cttttcattg tctgtctact cttattagct gctacataac tcaaagtaac 1440 aaacataeae atataacata tagaaagatc gaaaacaaaa gatcgggatg agtatggctc 1500 caaagacctc aactacactt gctttattcc ttgtgaecaa tattctcttc ctcaacctca 1560 ttaccctgag ttgcgcagac aatacttgcc caagagacgt tetcaaactt tcgacatgct 1620 cgaatgttct caacctcatc aacttgaage teggggcacc agctatgagg ccttgttgct 1680 ctattctctt tggtctaatt gatctcgatg ttgcggtttg cctttgcacc gcgctcaagc 1740 tcagccttct tggcatcacc atcgacactc ctattcacct taacttggct cttaacgcct 1800 gtggaggtac ccttcctgat ggattccgtt gcccaacata gctacaatat attcatattt 1860 tctatctatg ttcttgaatt ggtttTgtct aacatccaaa ttcaaaccta aattcatgta 1920 taagcaaata acaagtaaaa ttaagacttt tatg (2) INFORMATION FOR SEQ ID NO: 128: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 496 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS: (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..496 (D) OTHER INFORMATION: / Ceres Seq. ID 2025480
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 128: Met Glu Pro Tyr He Thr Arg Arg Asp Thr Val A.sn Gin Val Leu His 1 5 10 15
Ala Glu Glu Glu Glu Glu Tyr Asn A.sp Cvs Glu Leu Asp Gin Leu Phe 20 25" ' 30
Leu Val His Ser Asp He A.rg Ser Val Leu Leu Gin He Asp Glu Leu
35 " " 40 45
Val Val Glu Ala Thr Lys A.rg Lys Thr Val Ser Lys His Gly Leu He 50 55 60 Glu Val Glu Ser Phe Arg Thr Val Leu Ser Asp Met Leu Ser Ser Leu 65 70 75 80
Lys Pro Trp Phe Pro Arg Leu Gin Glu Ala Met Ser Asp Phe Gin Leu
85 90 95
Leu Pro Glu Asp Gin Glu Glu Gin Ser Leu Met Ser Thr Asn Glu Glu 100 105 110
Glu Asp Leu Phe Asp Val Glu Ser Pro Glu Pro Thr Gin Phe Glu Pro
115 120 125
Leu Val Ser Pro Ser Pro Leu Val His Trp Arg Gly Asp His Asn Ala
130 135 140 Asp Lys Gly Arg Gin Leu Phe Leu Leu Thr Pro Leu Pro Leu Gly Lys
145 150 155 160
Ser Glu Phe Leu Lys His Gin Asn Ala Ser Lys Leu Thr Ala Lys A.rg
165 170 175
He Phe Pro Asp Thr Val Ala Asn Glu Pro Leu Glu Ala Ser Lys Glu 180 185 190
Thr Ser Asp Asp Val Leu Gly Gly Glu Ser Leu Lys Thr Ala Gly Leu
195 200 205
Gly Lys Ser Leu Val His Ala Met Asp Phe Ser Glu Asn Leu Val Glu
210 215 220 Tyr Lys Pro Cys Ser Ser Pro Val Leu Arg Arg Lys He Leu Ser Glu
225 230 235 240
Leu Leu Met Thr Pro Cys Leu Lys Leu Ser Pro Pro Lys Ser Cys Thr
245 250 255
Met Phe Lys Pro Val Pro Glu Ser Ser Gin Leu Gly Lys Gin Gly Ala 260 265 270
Cys Lys Ser Thr Cys Ser Glu Leu Gly Ser Ser Gly He Glu Lys Thr
275 280 285
Asp Asn Leu Cys Ser Lys Tyr Pro Glu Leu Leu Gly He Gin His Ala
290 295 300 Pro He Thr Arg Lys Thr Asp Leu Glu Ser Ser Pro Val Trp Trp Phe
305 310 315 320
Ser Pro Pro Lys Thr Cys Val Leu Met Glu Pro Val A.sn Glu Lys Lys
325 330 335
Pro He Asp Glu Thr Gly Gly Ser Phe Asp Val Pro Asn He He Pro 340 345 350
Glu Ala Lys His Thr Thr Glu Gly Ser Met Ser Met Val Val Glu Ser 355 360 365 Thr Pro Leu Phe Lys Glu Pro Glu Ser He Met Thr Arg Asn Arg Thr
370 375 380
Lys Ala Gly Glu Ser Thr Leu Lys Lys Glu Leu Trp Thr Arg Phe Glu 385 390 395 400 Glu Ala Thr He His Asp Ser Arg Phe Asn Ser Met Thr Thr Thr Thr
405 410 415
Thr Val Arg Gly Asn Asn Lys Lys Cys Phe Met Glu Met Leu Glu Glu
420 425 430
Val Ser Gly Asn Glu Glu Asp His Glu Leu Ser Gly Glu Phe Val Ala 435 440 445
Leu Lys Pro Tyr Gin Val Leu He Ser Glu Leu Ser He Thr A.sn Ala
450 455 460
Phe His Cys Leu Ser Thr Leu He Ser Cys Tyr He Thr Gin Ser Asn 465 470 475 480 Lys His Thr His He Thr Tyr Arg Lys He Glu A.sn Lys Arg Ser Gly
485 490 495
'2) INFORMATION FOR SEQ ID NO: 129: U) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 421 amino acids
. C STRANDEDNESS: D) TOPOLOGY: linear ,n, MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..421
(D) OTHER INFORMATION: / Ceres Seq. ID 2025481 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 129: Met Leu Ser Ser Leu Lys Pro Trp Phe Pro Arg Leu Gin Glu Ala Met 1 5 10 15
Ser Asp Phe Gin Leu Leu Pro Glu Asp Gin Glu Glu Gin Ser Leu Met
20 25 30
Ser Thr Asn Glu Glu Glu Asp Leu Phe Asp Val Glu Ser Pro Glu Pro 35 40 45 Thr Gin Phe Glu Pro Leu Val Ser Pro Ser Pro Leu Val His Trp Arg 50 55 60
Gly Asp His Asn Ala A.sp Lys Gly A.rg Gin Leu Phe Leu Leu Thr Pro 65~ 0 " 75 80
Leu Pro Leu Gly Lys Ser Glu Phe Leu Lys His Gin Asn Ala Ser Lys 85 90 95
Leu Thr Ala Lys Arg He Phe Pro Asp Thr Val Ala Asn Glu Pro Leu
100 105 110
Glu Ala Ser Lys Glu Thr Ser Asp Asp Val Leu Gly Gly Glu Ser Leu 115 120 125 Lys Thr Ala Gly Leu Gly Lys Ser Leu Val His Ala Met Asp Phe Ser 130 135 140
Glu Asn Leu Val Glu Tyr Lys Pro Cys Ser Ser Pro Val Leu A.rg Arg 145 150 " 155 160
Lys He Leu Ser Glu Leu Leu Met Thr Pro Cys Leu Lys Leu Ser Pro 165 170 " 175
Pro Lys Ser Cys Thr Met Phe Lys Pro Val Pro Glu Ser Ser Gin Leu
180 185 190
Gly Lys Gin Gly Ala Cys Lys Ser Thr Cys Ser Glu Leu Gly Ser Ser 195 200 205 Gly He Glu Lys Thr Asp Asn Leu Cys Ser Lys Tyr Pro Glu Leu Leu 210 215 220
Gly He Gin His Ala Pro He Thr Arg Lys Thr Asp Leu Glu Ser Ser 225 230 235 240
Pro Val Trp Trp Phe Ser Pro Pro Lys Thr Cys Val Leu Met Glu Pro 245 250 255
Val Asn Glu Lys Lys Pro He Asp Glu Thr Gly Gly Ser Phe Asp Val 260 265 270 Pro Asn He He Pro Glu Ala Lys His Thr Thr Glu Gly Ser Met Ser
275 280 285
Met Val Val Glu Ser Thr Pro Leu Phe Lys Glu Pro Glu Ser He Met
290 295 300 Thr Arg Asn Arg Thr Lys Ala Gly Glu Ser Thr Leu Lys Lys Glu Leu
305 310 315 320
Trp Thr A.rg Phe Glu Glu A.la Thr He His Asp Ser Arg Phe Asn Ser
325 330 335
Met Thr Thr Thr Thr Thr Val Arg Gly Asn Asn Lys Lys Cys Phe Met 340 " 345 " " 350
Glu Met Leu Glu Glu Val Ser Gly Asn Glu Glu Asp His Glu Leu Ser
355 360 365
Gly Glu Phe Val Ala Leu Lys Pro Tyr Gin Val Leu He Ser Glu Leu
370 375 380 Ser He Thr Asn Ala Phe His Cys Leu Ser Thr Leu He Ser Cys Tyr
385 390 395 400
He Thr Gin Ser Asn Lys His Thr His He Thr Tyr A.rg Lys He Glu
405 410 415
Asn L s Arg Ser Gly " 420 "
! INFORMATION FOR SEQ II MO: 130: 'i; SEQUENCE CHARACTERISTICS:
(A) LENGTH: 406 amino acids (E) TYPE: amino acid (C! STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..406
(D) OTHER INFORMATION: / Ceres Seq. ID 2025482 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 130: Met Ser A.sp Phe Gin Leu Leu Pro Glu Asp Gin Glu Glu Gin Ser Leu 1 5 10 15 Met Ser Thr Asn Glu Glu Glu Asp Leu Phe Asp Val Glu Ser Pro Glu
20 25 30
Pro Thr Gin Phe Glu Pro Leu Val Ser Pro Ser Pro Leu Val His Trp
35 40 45
Arg Gly A.sp His Asn Ala Asp Lys Gly Arg Gin Leu Phe Leu Leu Thr 50 55~ " 60
Pro Leu Pro Leu Gly Lys Ser Glu Phe Leu Lys His Gin Asn A.la Ser 65 70 75 80
Lys Leu Thr Ala Lys A.rg He Phe Pro Asp Thr Val A.la Asn Glu Pro 85 90 95 Leu Glu Ala Ser Lys Glu Thr Ser Asp Asp Val Leu Gly Gly Glu Ser
100 105 110
Leu Lys Thr Ala Gly Leu Gly Lys Ser Leu Val His A.la Met Asp Phe
115 120 125
Ser Glu Asn Leu Val Glu Tyr Lys Pro Cys Ser Ser Pro Val Leu Arg 130 135 " 140
A.rg Lys He Leu Ser Glu Leu Leu Met Thr Pro Cys Leu Lys Leu Ser
145 150 155 160
Pro Pro Lys Ser Cys Thr Met Phe Lys Pro Val Pro Glu Ser Ser Gin
165 " 170 175 Leu Gly Lys Gin Gly Ala Cys Lys Ser Thr Cys Ser Glu Leu Gly Ser
180 185 190
Ser Gly He Glu Lys Thr A.sp A.sn Leu Cys Ser Lys Tyr Pro Glu Leu
195 200 205
Leu Gly He Gin His Ala Pro He Thr Arg Lys Thr A.sp Leu Glu Ser 210 215 ' 220
Ser Pro Val Trp Trp Phe Ser Pro Pro Lys Thr Cys Val Leu Met Glu 225 230 235 240 Pro Val Asn Glu Lys Lys Pro He Asp Glu Thr Gly Gly Ser Phe Asp 245 250 255
Val Pro Asn He He Pro Glu Ala Lys His Thr Thr Glu Gly Ser Met 260 265 270
Ser Met Val Val Glu Ser Thr Pro Leu Phe Lys Glu Pro Glu Ser He 275 280 285
Met Thr Arg Asn Arg Thr Lys Ala Gly Glu Ser Thr Leu Lys Lys Glu 290 295 300
Leu Trp Thr Arg Phe Glu Glu Ala Thr He His Asp Ser Arg Phe Asn
305 310 315 320
Ser Met Thr Thr Thr Thr Thr Val Arg Gly Asn Asn Lys Lys Cys Phe 325 330 335
Met Glu Met Leu Glu Glu Val Ser Gly A.sn Glu Glu Asp His Glu Leu 340 345 350
Ser Gly Giu Phe Val Ala Leu Lys Pro Tyr Gin Val Leu He Ser Glu 355 360 365
Leu Ser He Thr Asn Ala Phe His Cys Leu Ser Thr Leu He Ser Cys 370 375 380
Tyr He Thr Gin Ser Asn Lys His Thr His He Thr Tyr Arg Lys He
385 390 395 400
Glu A.sn Lys A.rg Ser Gly
405 INFORMATION FOR SEQ ID NO: 131: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 609 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY:
(B) LOCATION: 1..609
(D) OTHER INFORMATION: / Ceres Seq. ID 2032963 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 131: tttgtgtggt aattaactgg tgagagagtt caacatccaa tctttctctc tctctctcta 60 tcttttatet ctcacactct taaaatgctt cttctatctc cgatctetgc etctctteca 120 ccgtcgtttc accggggtaa tttgatccgg cgatcaatta agccgttagg tagggttgtt 180 gcaaaggcca aggacaacac cgacactggt ggatttctgg agacggcagc tatagccggt 240 agtttagtgt cgacgccggt tattggatgg tcactctaca ctttgaagac cacgggatgt 300 ggcttacctc ccggaccggc cggtttaatc ggagcgttgg aaggtgtgag ctacttggtg 360 gtggttggca tcgtgggctg gtctttgtac actaaaacaa aaactgggtc aggtctgcca 420 aatgggccat ttggtttgtt gggtgcggtc gagggtttat cgtatctgtc ggttctagcc 480 attcttgtgg tgtttggtat tcagttcttg gataatgggt cggttccagg tccacttcct 540 agtgaccagt gttttggtta accacgtgta atgtcgtata aataaagtgt caaattaata 600 attgctttc (2) INFORMATION FOR SEQ ID NO: 132:
(i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 158 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE peptide (ix) FEATURE :
(A) NAME/KEY peptide
(B) LOCATION 1..158
(D) OTHER INFORMATION: / Ceres Seq. I D 2032964
(xi! SEQUENCE DESCRIPTION: SEQ ID NO: 132:
Met Leu Leu Leu Ser Pro He Ser Ala Ser Leu Pro Pro Ser Phe His
1 5 10 15
Arg Gly Asn Leu He A.rg A.rg Ser He Lys Pro Leu Gly Arg Val Val
20 25 30
Ala Lys Ala Lys Asp Asn Thr Asp Thr Gly Gly Phe Leu Glu Thr Ala 35 40 45
Ala He Ala Gly Ser Leu Val Ser Thr Pro Val He Gly Trp Ser Leu
50 55 60
Tyr Thr Leu Lys Thr Thr Gly Cys Gly Leu Pro Pro Gly Pro A.la Gly 65 70 75 80
Leu He Gly Ala Leu Glu Gly Val Ser Tyr Leu Val Val Val Gly He
85 90 95
Val Gly Trp Ser Leu Tyr Thr Lys Thr Lys Thr Gly Ser Gly Leu Pro
100 105 110
Asn Gly Pro Phe Gly Leu Leu Gly Ala Val Glu Gly Leu Ser Tyr Leu
115 120 125
Ser Val Leu Ala He Leu Val Val Phe Gly He Gin Phe Leu Asp A.sn
130 135 140
Gly Ser Val Pro Gly Pro Leu Pro Ser Asp Gin Cys Phe Gly
145 150 155
(2) INFORMATION FOR SEQ ID NO: 133: ,'i) SEQUENCE CHARACTERISTICS:
(A.) LENGTH: 330 base pairs (B) TYPE: nucleic acid STRANDEDNESS: single TOPOLOGY: .Linear ii; MOLECULE TYPE: DMA genomic; (ix; FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..330 iD) OTHER INFORMATION: / Ceres Seq. ID 2033706
■'xi) SEQUENCE DESCRIPTION: SEQ ID NO: 133: atgggccaca gagtgacgag agagagagtg aaaatggaga agtactttgg aaatgcgtac 60 aggggagatc caggagtgcc acatgeagat gcagatcgtt tegtgaatat atggattggt 120 tctgctgett tctccgttct tacctgggtt aatccttaca tgtggeagct ctctaaccag 180 ttcaattacc atgacaagtg gatgctgttt gagcagtacc actggaaaaa agcaagggca 240 aagaagcaac cttatgaatt caagtggaat aagataccca aagaagtcag ggactcgtac 300 tattacaact ggccagtcta cttcccatag (2) INFORMATION FOR SEQ ID NO: 134: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 109 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear in) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..109
(D) OTHER INFORMATION: / Ceres Seq. ID 2033707 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 134: Met Gly His Arg Val Thr Arg Glu Arg Val Lys Met Glu Lys Tyr Phe 1 5 10 15
Gly Asn Ala Tyr Arg Gly Asp Pro Gly Val Pro His A.la A.sp Ala Asp
20 25 30
Arg Phe Val Asn He Trp He Gly Ser Ala Ala Phe Ser Val Leu Thr
35 40 45
Trp Val Asn Pro Tyr Met Trp Gin Leu Ser Asn Gin Phe Asn Tyr His
50 55 60
Asp Lys Trp Met Leu Phe Glu Gin Tyr His Trp Lys Lys Ala Arg Ala 65 70 75 80
Lys Lys Gin Pro Tyr Glu Phe Lys Trp Asn Lys He Pro Lys Glu Val
85 90 95
Arg Asp Ser Val Tyr Phe Pro
(2) INFORMATION FOR SEQ ID NO: 135: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 98 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (11) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..98 (D) OTHER INFORMATION: / Ceres Seq. ID 2033708
(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 135: Met Glu Lys Tyr Phe Gly Asn Ala Tyr Arg Gly Asp Pro Gly Val Pro 1 5 10 15
His Ala Asp Ala Asp Arg Phe Val Asn He Trp He Gly Ser Ala Ala
20 25 30
Phe Ser Val Leu Thr Trp Val Asn Pro Tyr Met Trp Gin Lea Ser Asn 35 40 45
Gin Phe Asn Tyr His Asp Lys Trp Met Leu Phe Glu Gin Tyr His Trp
50 55 60
Lys Lys Ala A.rg Ala Lys Lys Gin Pro Tyr Glu Phe Lys Trp Asn Lys 65 70 SO lie Pro Lys Glu al Arg ASP Ser T r Tyr Tyr Asn Trp Pre Val T ,-r
85 ι 93
Pre Pro
(2) INFORMATION FOP SEQ ID MO: 136: ι; SEQUENCE CHARACTERISTICS:
(A) LENGTH: 56 ammo acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1.. ^6 (D) OTHER INFORMATION: / Ceres Seq. ID 2033709 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 136:
Met Trp Gin Leu Ser Asn Gin Phe A.sn Tyr His A.sp Lys Trp Met Leu 1 5 10 15
Phe Glu Gin Ty_ His Trp Lys Lys A.__a A.rg A.la Lys Lys Gin Pro Tyr 20 25 " " 30 Glu Phe Lys Trj Asn Lys He Pro Lys Glu Val A.rg Asp Ser Tyr Tyr 35 40 45 Tyr Asn Trp Pro Val Tyr Phe Pro
50 55
(2) INFORMATION FOR SEQ ID MO: 137: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 418 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..418
(D) OTHER INFORMATION: / Ceres Seq. ID 2043118 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 137: ataacaatat caaaagataa aaacagagtt tgcttttata agatcaaaga aggtaaaaaa 60 agaaatggca aaatggagtg cgategtatt gataatgatg gtgatgattg ttgcggtcac 120 aatagaagca eaagaagaaa gtggtgggac tatttgtttt cgccaatgtt ctcagccttg 180 tcgcagtgac gacggtagtt gctatoaaaa ctgtaaaatc gaatgcggtg gtcccaagcc 240 tcccttatct cgtctacgaa gctcacatgc atgagatggc atcatcaatg gaagttegcg 300 gaaggatagg atgataaaaa gagatttgta gcggattttt gatcatctct actgttttta 360 acttcacgtt ttatattata agagtttcat taaaaagatc aataaaacga gaaaatgt (2) INFORMATION FOR SEQ ID NO: 138: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 69 ammo acids (C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..69
(D) OTHER INFORMATION: / Ceres Seq. ID 2043119 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 138: Met Ala Lys Trp Ser Ala He Val Leu He Met Met Val Met He Val 1 5 10 15 Ala val Thr He Glu Aia Gin Glu Glu Ser Gly Giy Thr He Cys Phe
20 25 30
._rσ Gin C s Ser Gin Pro Cys Arg Ser Asp Asp Gly Ser Cys T r Glu
35 40 45 πsn Cys Lys He Glu C 's Giv Gly Pro Lys Pro Pro Leu Ser Arq Leu 50 55 " 60 65 2 INFORMATION FOR SEQ ID NO: 139: 1' SEQUENCE CHARACTERISTICS: i A) LENGTH: 62 ammo aciαs C) STRANDEDNESS:
(D) TOPOLOGY: linear ill) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..62
(D) OTHER INFORMATION: / Ceres Seq. ID 2043120 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 139: He Thr He Ser Lys Asp Lys Asn Arg Val Cys Phe Tyr Lys He Lys 1 5 10 15
Glu Gly Lvs Lys Arg A.sn Gly Lys Met Glu Cys A.sp A.rg He Asp A.sn
20 25 30
Asp Gly Asp Asp Cys Cys Giy His Asn A.rg Ser Thr Arg Arg Lys Trp 35 40 45
Trp Asp Tyr Leu Phe Ser Pro Met Phe Ser Ala Leu Ser Gin
50 55 60
(2) INFORMATION FOR SEQ ID NO: 140: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 59 amino acids
(C) STRANDEDNESS:
(D) TOPOLOGY: linear iii) MOLECULE TYPE: peptide vix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..59
(D) OTHER INFORMATION: / Ceres Seq. ID 2043121 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 140: Met Met Val Met He Val Ala Val Thr He Glu Ala Gin Glu Glu Ser 1 5 10 15
Gly Gly Thr He Cys Phe Arg Gin Cys Ser Gin Pro Cys Arg Ser Asp
20 25 30
Asp Gly Ser Cys Tyr Glu Asn Cys Lys He Glu Cys Gly Gly Pro Lys 35 40 45
Pro Pro Leu Ser Arg Leu Arg Ser Ser His Ala 50 55 (2) INFORMATION FOR SEQ ID NO: 141: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 838 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..838
(D) OTHER INFORMATION: / Ceres Seq. ID 2047214 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 141: acacgaaacg attccgcttc tccgcttcct tcataaatat ctcactcatc gtctctagat 60 tgttctttca cacgcaattt tcatttctct cttaaccgta aacgaatctc tettctcaaa 120 gttttatttt etctctgcga tggctcaaga agatgttact gctgttgcta ctaacggtgc 180 tggtccggtg gagacgcatc ttgtcttcac tgagttcaag cagatgttgc tcgttgaagc 240 tcaaaaggte ggtgacgctg ttactttcta caaatctgct tttggtgcga tcgagtetgg 300 tcattctctt taccctaagc gtaagcttga ccaagagctt cctcatgttc tctcttctga 360 gcttaatctc gctggctctt ccttcgttgt ttgcgacgtt tcctctctcc ctggtttttc 420 tactoegaaa tcggaaggtt cgggagtgac ttttcttctc ggaactaagg atgctgaagc 480 cgccgttgcg aaagctgttg acgccggagc tgtgaaagtg gaggttacgg aggcagaagt 540 tgaactggga ttcaaaggaa aagttacgga tccttttggt gtcacttgga tcttcgcgga 600 gaagaagacc gtgatcaccg acgagaacaa agaggtttag aatctgtcgt cggatctaat 660 tcttcgtcgg tttctgaaca aaaaaaacta tctattatcc taggtttatg cttttatttt 720 gtcttttgtg gaatccggta atcagtaaac cggatcgagt aggctaatga ctttcggatt 780 ctaatttcac cccttttgac aaactctaat cttggtgaaa ttgcatatta atctcggg (2) INFORMATION FOR SEQ ID NO: 142: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 166 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..166
(D) OTHER INFORMATION: / Ceres Seq. ID 2047215 (xi; SEQUENCE DESCRIPTION: SEQ ID NO: 142: Met Ala Gin Glu Asp Val Thr Ala Val Ala Thr Asn Gly Ala Gly Pro 1 5 10 15
Val Glu Thr His Leu Val Phe Thr Glu Phe Lys Gin Met Leu Leu Val
20 25 30
Glu Ala Gin Lys Val Gly Asp Ala Val Thr Phe Tyr Lys Ser A.la Phe 35 40 45 Gly Ala He Glu Ser Gly His Ser Leu Tyr Pro Lys Arg Lys Leu Asp 50 55 60
Gin Glu Leu Pro His Val Leu Ser Ser Glu Leu Asn Leu Ala Gly Ser 65 70 75 80
Ser Phe Val Val Cys Asp Val Ser Ser Leu Pro Gly Phe Ser Thr Ala 85 90 95
Lys Ser Glu Gly Ser Gly Val Thr Phe Leu Leu Gly Thr Lys A.sp A.la
100 105 110
Glu Ala Ala Val Ala Lys Ala Val Asp Ala Gly Ala Val Lys Val Glu 115 120 125 Val Thr Glu Ala Glu Val Glu Leu Gly Phe Lys Gly Lys Val Thr Asp 130 135 140
Pro Phe Gly Val Thr Trp He Phe Ala Glu Lys Lys Thr Val He Thr 145 150 155 160
Asp Glu Asn Lys Glu Val 165
(2) INFORMATION FOR SEQ ID NO: 143: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 138 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..138
(D) OTHER INFORMATION: / Ceres Seq. ID 2047216 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 143:
Met Leu Leu Val Glu Ala Gin Lys Val Gly A.sp Ala Val Thr Phe Tyr 1 5 10 15
Lys Ser Ala Phe Gly Ala He Glu Ser Gly His Ser Leu Tyr Pro Lys 20 25 " 30 A.rg Lys Leu Asp Gin Glu Leu Pro His Val Leu Ser Ser Glu Leu Asn 35 40 45
Leu A.la Gly Ser Ser Phe Val Val Cys A.sp Val Ser Ser Leu Pro Gly
50 55 ' 60
Phe Ser Thr Ala Lvs Ser Giu Gly Ser Glv Val Thr Phe Leu Leu Gly 65 70 " - 5θ'
Thr Lys Asp Ala Glu A.la Ala Val A.la Lys A.la Val Asp Ala Giy Ala
65 90 95
Val Lys Val Glu Val Thr Glu Ala Glu Val Glu Leu Gly Phe Lys Gly 100 105 110 Lys Val Thr Asp Pro Phe Giy Val Thr Trp He Phe Aia Glu Lys Lys 115 120 125
Thr Val He Thr Asp Glu A.sn Lys Glu Val
130 135
(2) INFORMATION FOR SEQ ID NO: 144: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 98 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A.) NAME/KEY: peptide (3) LOCATION: 1..98
(D) OTHER INFORMATION: / Ceres Seq. ID 2047217 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 144:
Met Leu Leu Leu Leu Leu Leu Thr Val Leu Val A.rg Trp Arg Arg He 1 5 10 15
Leu Ser Ser Leu Ser Ser Ser Arg Cys Cys Ser Leu Lys Leu Lys Arg 20 25 30 Ser Val Thr Leu Leu Leu Ser Thr Asn Leu Leu Leu Val Arg Ser Ser 35 40 45
Leu Val He Leu Phe Thr Leu Ser Val Ser Leu Thr Lys Ser Phe Leu
50 55 60
Met Phe Ser Leu Leu Ser Leu He Ser Leu Ala Leu Pro Ser Leu Phe 65 70 75 80
Ala Thr Phe Pro Leu Ser Leu Val Phe Leu Leu Arg Asn Arg Lys Val
85 90 95
Arg Glu 12 ) INFORMATION FOR SEQ ID NO: 145: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 682 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single (D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..682
(D) OTHER INFORMATION: / Ceres Seq. ID 2047438 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 145: atgattggtg gtttcttcgc cgatgtaaaa ttcaacagat cgagagagaa aaaactctct 60 ctccctcctc cgttcaccgt cgcgactcgg ctctacagta cattttgttg agcaatctcg 120 tatttagagg attccaatgt ctggcgcaga ggataataaa tcttcccatg ctcagctttc 180 gtcccaaatt tttcttgatc ttgtggattc ggtgatagct gatgtagcat ctgagtgtca 240 tcgggtagca cgactaggac ttgatcgtga tttggatata gtagaagaag agttgagatt 300 gtcagtggaa gcgcgtgega agatcgctga tcctagcaac aacctcgaaa ccaacaccaa 360 atatgttgtt gatatatttg ggcagactca ccctcctgta gctagtgaag tgttcaattg 420 catgaactgt gggcgacaaa ttgttgcagg aaggtttgct cctcatctcg aaaaatgcat 480 gggaaaggga agaaaggctc gtgccaagac aaccagaagc acaacggctg cacagaaccg 540 gaatgcacga egcagcccca atccacgata ttctccttat ccaaattctg ctagtgagaa 600 ccagttagca agtggatcac ctggtgttgc aggtgaagac tgctcaaatt tcacagttcg 660 agagaacgtg aaaggagact ga (2) INFORMATION FOR SEQ ID NO: 146: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 181 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi, MOLECULE TYPE: peptide 'ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..181
(D) OTHER INFORMATION: / Ceres Seq. ID 2047439 (xi) SEQUENCE DESCRIPTION: SEQ ID NO:146: Met Ser Gly Ala Glu Asp Asn Lys Ser Ser His Ala Gin Leu Ser Ser 1 5 10 15
Gin He Phe Leu Asp Leu Val Asp Ser Val He Ala Asp Val Ala Ser
20 25 30
Glu Cys His Arg Val Ala Arg Leu Gly Leu Asp Arg Asp Leu Asp He 35 40 45 Val Glu Glu Glu Leu Arg Leu Ser Val Glu Ala Arg Ala Lys He Ala 50 55 60
A.sp Pro Ser Asn Asn Leu Glu Thr Asn Thr Lys Tyr Val Val A.sp He 65 70 75 80
Phe Gly Gin Thr His Pro Pro Val Ala Ser Glu Val Phe Asn Cys Met 85 90 95
Asn Cys Gly Arg Gin He Val Ala Gly Arg Phe Ala Pro His Leu Glu
100 105 110
Lys Cys Met Gly Lys Gly Arg Lys Ala Arg Ala Lys Thr Thr Arg Ser 115 120 125 Thr Thr Ala Ala Gin Asn Arg Asn Ala Arg Arg Ser Pro Asn Pro Arg 130 135 140
Tyr Ser Pro Tyr Pro Asn Ser Ala Ser Glu A.sn Gin Leu Ala Ser Gly 145 150 155 160
Ser Pro Gly Val Ala Gly Glu Asp Cys Ser Asn Phe Thr Val Arg Glu 165 170 175
Asn Val Lys Gly Asp
180 (2) INFORMATION FOR SEQ ID NO: 147: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 501 base pairs
(B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..501 (D) OTHER INFORMATION: / Ceres Seq. ID 2049056 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 147: aaacaaaggt gtcaagaaga aggatcaaca tattaattga ctaaaaatga aggcatggat 60 gataatcttg ttggtgattt gtgtcgctgt ggtggtggag caatcagagg ctcgcaaagg 120 tcgaaagtat ttaaatccag gcgtgcttga- ccggtgtcgt ggtcctaatc ctccagcggg 180 atgtcatcct cacaattccc accacaaacc tcgcgtccct gttcacaatt atagtcgtgg 240 ttgtagtaga attacccggt gcagacgaga tgcctaggtt taacctcaca tgacgacgac 300 gtccctttat attgatcctt cttctacatg agacttgcaa tgatattata tattcatata 360 tatacacatt aegctgtata tgataattcc agttgattaa tatataaatc ttactgattt 420 caattcaata cacaagatcc tgtaactgaa ataattttgt ccatgttttg tgcttataat 480 aatggtatga ctcttattat t (2) INFORMATION FOR SEQ ID NO: 148: ,'i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 76 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS: ■D) TOPOLOGY: linear ii, MOLECULE TYPE: peptide ix,' FEATURE: 'A! NAME/KEY: peptide
3; LOCATION: 1..76
.D) OTHER INFORMATION: / Ceres Seq. IC 2049057 xi, SEQUENCE DESCRIPTION: SEQ ID MO: 148: Met Lys Ala Trp Met He He Leu Leu Val He Cys Val Ala Val Val 1 5 10 15
Val Glu Gin Ser Glu Ala A.rg Lys Gly A.rg Lys Tyr Leu A.sn Pro Gly
20 25 30
Val Leu Asp Arg Cys Arg Gly Pro A.sn Pro Pro A.la Gly Cys His Pro 35 40 45 His Asn Ser His His Lys Pro Arg Val Pro Val His Asn Tyr Ser Arg 50 55 60
Gly Cys Ser Arg He Thr art Cys Arg Arg A.sp Ala 65 ' 70 75
(2) INFORMATION FOR SEQ ID NO: 149: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 72 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide
Hx) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..72
(D) OTHER INFORMATION: / Ceres Seq. ID 2049058 .xi) SEQUENCE DESCRIPTION: SEQ ID NO: 149:
Met He He Leu Leu Val He Cys Val Ala Val Val Val Glu Gin Ser 1 5 10 15
Glu A.la Arg Lys Gly Arg Lys Tyr Leu Asn Pro Gly Val Leu Asp Arg 20 25 30 Cys A.rg Gly Pro Asn Pro Pro Ala Gly Cys His Pro His Asn Ser His 35 40 45
His Lys Pro Arg Val Pro Val His Asn Tyr Ser A.rg Gly Cys Ser Arg
50 55 60
He Thr A.rg Cys Arg Arg Asp Ala 65 70
(2) INFORMATION FOR SEQ ID NO: 150: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 1007 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..1007
(D) OTHER INFORMATION: / Ceres Seq. ID 2050386 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 150: ccaaatttct ccatggatcg ttctttgaat ctcctcgatt tagccttagg gttcgatgag 60 cagctageta ttccatcgcc actaaatgga aaagtaatac taatagaaga ctgtgtagag 120 acgagtggtt cctttgtact tcaccagcta atgaaacgtg ttctctcctc taactcctcc 180 gacgcaetta tctttctcgc ttttgctcgc cctttctctc attatgatcg aatcttgcgt 240 aaactgggat gtaatttagc tacccataag tcgaataatc gattggtgtt ctttgacatg 300 ctcatggtta agtgttcaga tggggatcaa atggaagaca atgtgagtgc agttgcgaaa 360 ctatttcggg agatacaaga aaccgttcga aagctacaga gtgtaacaag tggtaacata 420 actgttatgg tggatgacat gtctctgctg gaaattgcta ctaccggcag caactcagat 480 cacgtattgg acttcttgca ttattgccac acattaagtt ctgaaagcaa ttgttcattg 540 gtcatcctca atcatgaaga tatatacgcg agcatggaga gacctgcatt tttgctacag 600 atggtatgcc ttgcagatgt tgtgataaag gcagagcctt tagcctctgg tttagcaaat 660 gatgtacatg gccaattgac tgttctgaac aaagggataa gcaactcagg tagaggaagc 720 tcgaggaaca agttgcagaa ttttcaattc aggatcaaag aaaatggtat cgactatttc 780 tatcctggtt gcagaagctg aggattagac accgttctga gcattagcat ggtagtgaga 840 tgtttttcta gacagttttg ttatttgcqt ttaggttaaa cagagacact ctgttaaaca 900 tttttacttt agtgtctett ctggttgtaa ettgatgact tagctaaagt tgaatgcttg 960 aqacacaqaa acttotaqac atqqaaaatt aqtaacattc tatatct
\ - ι INFORMATION FOR SEQ ID NO: 151:
(ι) SEQUENCE CHARACTERISTICS: (A) LENGTH: 266 amino acids ) TYPE: amino acid ) STRANDEDNESS: (D) TOPOLOGY: linear
(ϋ) MOLECULE TYPE: peptide (ix) FEATURE :
(A) NAME/KEY: peptide
(B) LOCATION: 1..266
(D) OTHER INFORMATION: / Ceres Seq. ID 2050387 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 151: Pro A.sn Phe Ser Met A.sp Arg Ser Leu Asn Leu Leu Asp Leu Ala Leu 1 5 10 15
Gly Phe Asp Glu Gin Leu Ala He Fro Ser Pro Leu A.sn Gly Lys Val
20 25 30
He Leu He Glu Asp Cys Val Glu Thr Ser Gly Ser Phe Val Leu His
35 40 45
Gin Leu Met Lys Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He
50 55 60
Phe Leu Ala Phe Ala Arg Pro Phe Ser His Tyr Asp Arg He Leu Arg 65 70 75 80
Lys Leu Gly Cys Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val
85 90 95
Phe Phe Asp Met Leu Met Val Lys Cys Ser Asp Gly Asp Gin Met Glu
100 105 110
Asp Asn Val Ser Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr
115 120 125
Val Arg Lys Leu Gin Ser Val Thr Ser Gly A.sn He Thr Val Met Val
130 " 135 140
Asp Asp Met Ser Leu Leu Glu He Aia Thr Thr Gly Ser Asn Ser Asp 145 150 155 160
His Val Leu Asp Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser
165 170 175
A.sn Cys Ser Leu Val He Leu Asn His Glu Asp He Tyr Ala Ser Met
180 185 190
Glu Arg Pro Ala Phe Leu Leu Gin Met Val Cys Leu Ala Asp Val Val
195 200 205
He Lys Ala Glu Pro Leu Ala Ser Gly Leu Ala Asn A.sp Val His Gly 210 215 220 Gin Leu Thr Val Leu Asn Lys Gly He Ser Asn Ser Gly Arg Gly Ser 225 230 235 240
Ser Arg Asn Lys Leu Gin Asn Phe Gin Phe Arg He Lys Glu Asn Gly 245 250 255 He Asp Tyr Phe Tyr Pro Gly Cys Arg Ser 260 265
(2) INFORMATION FOR SEQ ID NO: 152: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 262 amino acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..262
(D) OTHER INFORMATION: / Ceres Seq. ID 2050388 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 152: Met Asp Arg Ser Leu Asn Leu Leu Asp Leu Ala Leu Gly Phe Asp Glu 1 5 10 15
Gin Leu Ala He Pro Ser Pro Leu A.sn Gly Lys Val He Leu He Glu
20 25 30
Asp Cys Val Glu Thr Ser Gly Ser Phe Val Leu His Gin Leu Met Lys 35 40 45 Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He Phe Leu Ala Phe 50 55 60
Ala A.rg Pro Phe Ser His Tyr A.sp Arg He Leu Arg Lys Leu Gly Cys 65 70 75 80
Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val Phe Phe Asp Met 85 9θ" 95
Leu Met Val Lys Cys Ser A.sp Gly Asp Gin Met Glu Asp Asn Val Ser
100 105 110
Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr Val Arg Lys Leu 115 120 125 Gin Ser Val Thr Ser Gly Asn He Thr Val Met Val Asp Asp Met Ser 130 135 140
Leu Leu Glu He Ala Thr Thr Gly Ser Asn Ser Asp His Val Leu Asp 145 150 155 160
Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser Asn Cys Ser Leu 165 170 175
Val He Leu Asn His Glu Asp He Tyr A.la Ser Met Glu Arg Pro Ala
180 185 190
Phe Leu Leu Gin Met Val Cys Leu Ala Asp Val Val He Lys Ala Glu 195 200 205 Pro Leu Ala Ser Gly Leu Ala Asn Asp Val His Gly Gin Leu Thr Val 210 215 220
Leu Asn Lys Gly He Ser A.sn Ser Gly Arg Gly Ser Ser A.rg Asn Lys 225 230 235 240
Leu Gin Asn Phe Gin Phe Arg He Lys Glu Asn Gly He Asp Tyr Phe 245 J 250 255
Tyr Pro Gly Cys Arg Ser
260 (2) INFORMATION FOR SEQ ID NO: 153: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 216 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..216 (D) OTHER INFORMATION: / Ceres Seq. ID 2050389 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 153: Met Lys Arg Val Leu Ser Ser Asn Ser Ser Asp Ala Leu He Phe Leu 1 5 10 15 Ala Phe Ala Arg Pro Phe Ser His Tyr Asp Arg He Leu Arg Lys Leu 20 25 30
Gly Cys Asn Leu Ala Thr His Lys Ser Asn Asn Arg Leu Val Phe Phe
35 40 45
Asp Met Leu Met Val Lys Cys Ser Asp Gly Asp Gin Met Glu Asp Asn 50 55 60
Val Ser Ala Val Ala Lys Leu Phe Arg Glu He Gin Glu Thr Val Arg 65 70 75 80
Lys Leu Gin Ser Val Thr Ser Gly Asn He Thr Val Met Val Asp Asp 85 90 95 Met Ser Leu Leu Glu He Ala Thr Thr Gly Ser Asn Ser Asp His Val
100 105 110
Leu A.sp Phe Leu His Tyr Cys His Thr Leu Ser Ser Glu Ser Asn Cys
115 120 125
Ser Leu Val He Leu Asn His Glu Asp He Tyr Ala Ser Met Glu Arg 130 135 ' 140
Pro A.la Phe Leu Leu Gin Met Val Cys Leu A.la Asp Val Val He Lys
145 150 155 160
A.la Glu Pro Leu Ala Ser Gly Leu A.la A.sn Asp Val His Gly Gin Leu
165 170 175 Thr Val Leu Asn Lys Gly He Ser Asn Ser Gly Arg Gly Ser Ser Arg
180 185 190
Asn Lys Leu Gin Asn Phe Gin Phe A.rg He Lys Glu A.sn Gly He Asp
195 200 205
Tyr Phe Tyr Pro Gly Cys Arg Ser 210 ' 215
(2) INFORMATION FOR SEQ ID NO: 154: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 634 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..634
(D) OTHER INFORMATION: / Ceres Seq. ID 2053353 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 154: gaataaaaat ctatttcttg tgtttgtgtt gtatttactt aaaaaaataa aggagatcag 60 tttgggagaa agcagcaaag aagaaaaatg gcagcaacat ttgcaacacc atcgacggtg 120 ataggcctcg gaggatcatc catcaccacc aaacccttct cttcatcctt tttaaaacca 180 acattaagcg ccaagaaccc tttgagactc gccggtgcat cgggaggaag agtcacttgc 240 tttgagagga actggttgag gagagatttg aacgtggtag gatttgggct gatcggatgg 300 ctagctccgt cgagcattcc agcgataaat gggaagagcc tgacgggtct cttcttcgat 360 agcatcggaa ctgagctcgc tcacttcccg actcctccag ctctcacttc acagttctgg 420 ttgtggttgg ttacgtggca cttaggcctc ttcctctgcc tcactttcgg acaaatcgga 480 ttcaagggca ggactgaaga ttacttctaa ggataactat tcttgttttc gtttgtacta 540 tatgctctct cttggttatg tgtaatatta tcaatcaaaa caaagctttc tttgctattt 600 gatgtttcat tctatatctc gacaagtctt tctt (2) INFORMATION FOR SEQ ID NO: 155: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 140 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..140
(D) OTHER INFORMATION: / Ceres Seq. ID 2053354 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 155: Met Ala Ala Thr Phe Ala Thr Pro Ser Thr Val He Gly Leu Gly Gly 1 5 10 15
Ser Ser He Thr Thr Lys Pro Phe Ser Ser Ser Phe Leu Lys Pro "Ihr
20 25 30
Leu Ser Ala Lys Asn Pro Leu A.rg Leu Ala Gly Ala Ser Gly Gly Arg 35 40 45 Val Thr Cys Phe Glu Arg Asn Trp Leu Arg Arg A.sp Leu Asn Val Val 50 55 60
Gly Phe Gly Leu He Gly Trp Leu Ala Pro Ser Ser He Pro Ala He 65 70 75 80
Asn Gly Lys Ser Leu Thr Gly Leu Phe Phe Asp Ser He Gly Thr Glu 85 90 95
Leu Ala His Phe Pro Thr Pro Pro Ala Leu Thr Ser Gin Phe Trp Leu
100 105 110
Trp Leu Val Thr Trp His Leu Gly Leu Phe Leu Cys Leu Thr Phe Gly 115 120 125 Glr. He Gly Phe Lys Gly Arg Thr Giu Asp Tyr Phe 130 135 140
(2; INFORMATION FOR SEQ ID NO : 156 : ,'i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 393 base pairs (B) TYPE: nucleic acid
(C) STRANDEDNESS: single
(D) TOPOLOGY: linear
■ ii) MOLECULE TYPE: DNA. (genomic) (ix) FEATURE: (A) NAME/KEY: -
(B) LOCATION: 1..393
(D) OTHER INFORMATION: / Ceres Seq. ID 2055693 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 156: atgeaaaaac ctctctctct ctctcaattc acttctccte cttcaatggc ttggcgcaac 60 gcaggatctg ccgctcgttc tttcgtctcc gccaccgcaa gatcaccatc tctccgttct 120 cccaccacgg cgcttcctcg cctccgtcct cctcaatcct ccttacctag ccgtcgcttc 180 accttctcat caccttccag gaatctagga gcacttggtt gcacacagtc gttcttgcct 240 ctgtacagtg ttgtggctac ttctcaactc acatctcacc ttaacgttaa cttgcgagct 300 ttctgcgage tgtctaacgg gaattggaaa agatgggtga tgcactcgga ttttacgtcg 360 ctggcaagag aatggtgctg cattgttccg tga (2) INFORMATION FOR SEQ ID NO: 157: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 130 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear Hi) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..130
(D) OTHER INFORMATION: / Ceres Seq. ID 2055694 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 157: Met Gin Lys Pro Leu Ser Leu Ser Gin Phe Thr Ser Pro Pro Ser Met 1 5 10 15 Ala Trp Arg Asn Ala Gly Ser Ala Ala Arg Ser Phe Val Ser Ala Thr
20 25 30
A.la A.rg Ser Pro Ser Leu Arg Ser Pro Thr Thr Ala Leu Pro Arg Leu
35 40 45
Arg Pro Pro Gin Ser Ser Leu Pro Ser Arg Arg Phe Thr Phe Ser Ser 50 55 " 60
Pro Ser A.rg Asn Leu Gly Ala Leu Gly Cys Thr Gin Ser Phe Leu Pro 65 70 ' 75 80 Leu Tyr Ser Val Val Ala Thr Ser Gin Leu Thr Ser His Leu Asn Val
85 90 95
Asn Leu Arg Ala Phe Cys Glu Leu Ser Asn Gly Asn Trp Lys Arg Trp 100 105 110 Val Met His Ser Asp Phe Thr Ser Leu Ala Arg Glu Trp Cys Cys He 115 120 125
Val Pro 130 (2) INFORMATION FOR SEQ ID NO: 158: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 115 ammo acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (i ) MOLECULE TYPE: peptide
(ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..115
(D) OTHER INFORMATION: / Ceres Seq. IC 2055695 (xi, SEQUENCE DESCRIPTION: SEQ ID NO: 158:
Met Aia Trp A.rg Asn Ala Glv Ser A.la Ala Arg Ser Phe Val Ser A.la 1 5 10 " 15
Thr Ala Arg Ser Pro Ser Leu Arg Ser Pro Thr Thr Ala Leu Pro Arg 20 25 30 Leu Arg Pro Pro Gin Ser Ser Leu Pro Ser Arg A.rg Phe Thr Phe Ser 35 40 ' 45
Ser Pro Ser Arg Asn Leu Gly Ala Leu Gly Cys Thr Gin Ser Phe Leu
50 55 60
Pro Leu Tyr Ser Val Val Ala Thr Ser Gin Leu Thr Ser His Leu Asn 65 70 75 80
Val Asn Leu Arg Ala Phe Cys Glu Leu Ser Asn Gly Asn Trp Lys Arg
85 90 95
Trp Val Met His Ser Asp Phe Thr Ser Leu Ala Arg Glu Trp Cys Cys 100 105 110 He Val Pro 115 (2) INFORMATION FOR SEQ ID NO: 159: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 68 amino acids (B) TYPE: ammo acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (n) MOLECULE TYPE: peptide (ix) FEATURE: (A) NAME/KEY: peptide
(B) LOCATION: 1..68
(D) OTHER INFORMATION: / Ceres Seq. ID 2055696 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 159: Cys Lys Asn Leu Ser Leu Ser Leu Asn Ser Leu Leu Leu Leu Gin Trp 1 5 10 15
Leu Gly Ala Thr Gin Asp Leu Pro Leu Val Leu Ser Ser Pro Pro Pro
20 25 30
Gin Asp His His Leu Ser Val Leu Pro Pro Arg Arg Phe Leu Ala Ser 35 40 45 Val Leu Leu Asn Pro Pro Tyr Leu Ala Val Ala Ser Pro Ser His His 50 55 60
Leu Pro Gly He 65
(2) INFORMATION FOR SEQ ID NO: 160: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 394 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear
(11) MOLECULE TYPE: DNA (genomic)
(IX) FEATURE:
(A) NAME/KEY: -
(B) LOCATION: 1..394
(D) OTHER INFORMATION: / Ceres Seq. ID 2056405 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 160: tcaatagctt atctagttct tgactgttca acgatcaatg gcaccatceg ctgcaatqct 60 catactctca catcctctag ttagccacaa agctaagaat cagtctctgt catcgccgtc 120 gtctgttaag tcgacacgtg tcttcggttt tctttggcct tggaaggcat tagacaatga 180 ggatcattcc gcggttgttc tcggccggct ctttggcgat ccggctacta tcgagaagcg 240 cttccaagaa gctcttgaac aaagctgttg gtaatttgta caatgtttgg ttgggtttat 300 tgattgtttt tacgttaaaa tagcttttat aaattggaaa tggaagtact gtaaaatgta 360 aaaattgact atatataatt aaaggtacat tatg (2) INFORMATION FOR SEQ ID NO: 161: 'ι) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 78 amino acids i ) STRANDEDNESS: iD, TOPOLOGY: linear vii) MOLECULE TYPE: peptide MX) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..78
(D) OTHER INFORMATION: / Ceres Seq. ID 2056406 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 161: Met Ala Pro Ser Ala Ala Met Leu He Leu Ser His Pro Leu Val Ser 1 5 10 15 His Lys Ala Lys Asn Gin Ser Leu Ser Ser Pro Ser Ser Val Lys Ser
20 25 30
Thr Arg Val Phe Gly Phe Leu Trp P o Trp Lys A.la Leu Asp Asn Glu
35 40 45
Asp His Ser Ala Val Val Leu Gly Arg Leu Phe Gly Asp Pro Ala Thr 50 55 60
He Glu Lys Arg Phe Gin Glu Ala Leu Glu Gin Ser Cys Trp 65 70 75
{ 2 " INFORMATION FOR SEQ ID NO: 162: (l) SEQUENCE CHARACTERISTICS: (A) LENGTH: 72 amino acids
( B ) TYPE : ammo acid
( C ) STRANDEDNESS :
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..72
(D) OTHER INFORMATION: / Ceres Seq. ID 2056407 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 162: Met Leu He Leu Ser His Pro Leu Val Ser His Lys Ala Lys Asn Gin 1 5 10 15
Ser Leu Ser Ser Pro Ser Ser Val Lys Ser Thr Arg Val Phe Gly Phe
20 25 30
Leu Trp Pro Trp Lys Ala Leu Asp Asn Glu Asp His Ser Ala Val Val 35 40 45
Leu Gly Arg Leu Phe Gly Asp Pro Ala Thr He Glu Lys Arg Phe Gin
50 55 60
Glu Ala Leu Glu Gin Ser Cys Trp 65 70 (2) INFORMATION FOR SEQ ID NO: 163: (l) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 48 ammo acids (B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: 1..48
(D) OTHER INFORMATION: / Ceres Seq. ID 2056408 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 163: Met Arg He He Pro Arg Leu Phe Ser Ala Gly Ser Leu Ala He Arg 1 5 10 15
Leu Leu Ser Arg Ser Ala Ser Lys Lys Leu Leu Asn Lys A.la Val Gly
20 25 30
Asn Leu Tyr Asn Val Trp Leu Gly Leu Leu He Val Phe Thr Leu Lys 35 40 45
(2) INFORMATION FOR SEQ ID NO: 164: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 766 base pairs
(B) TYPE: nucleic acid (C) STRANDEDNESS: single
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (ix) FEATURE:
(A) NAME/KEY: - (B) LOCATION: 1..766
(D) OTHER INFORMATION: / Ceres Seq. ID 2065747 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 164: acagtcgcct ccttcctgcg ccgccgccgc cgccgccgct accaccgcct cgcggccgcc 60 tgcggctccg cgtttccgca cggatttggt gaaggtttct tgaggctgag aacatggtgc 120 tgaagacgga actttgccgc ttcagcggcc agaagattta tcctgggaaa ggcattagat 180 ttatccgtgc tgattctcag gtcttccttt ttgccaactc gaaatgcaag cgctacttcc 240 acaaccgcct gaagcctgca aagcttacct cgacagcaat gtacaggaag cagcacaaga 300 aggatatcca tgctgaagcg gtaaagaaga ggcgccgege caccaagaag ccatactcca 360 ggteaattgt gggtgcttcc ttggaagtaa tccagaagaa gagagctgag aagccagagg 420 tccgcgatgc tgctagagaa gctgctcttc gtgagatcaa ggagcgcatc aagaagacea 480 aggatgagaa gaaagcgaag aaggcggagg tgagcaagtc ccagaagacg cagacaaagg 540 gtgcggtcca gaagggttcc aagggcccca agttgggcgg cggtggtggg aagcgctgaa 600 agaacttagt gtcgtttctc gacattgcag tcgttcctta gccaaagcca ctttcgtaga 660 acctgtgttg aatttgcaag acttattcaa gcgttgcttg tgcgtgctaa ataccatggc 720 aagagaacgg atttatattt atgcctgaaa aaaaatgacc gttcat (2) INFORMATION FOR SEQ ID NO: 165: (i) SEQUENCE CHARACTERISTICS:
(A) LENGTH: 161 amino acids
(B) TYPE: amino acid (C) STRANDEDNESS:
(D) TOPOLOGY: linear (ii) MOLECULE TYPE: peptide (ix) FEATURE:
(A) NAME/KEY: peptide (B) LOCATION: 1..161
(D) OTHER INFORMATION: / Ceres Seq. ID 2065748 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 165: Met Val Leu Lys Thr Glu Leu Cys Arg Phe Ser Gly Gin Lys He Tyr 1 5 10 15 Pro Gly Lys Gly He Arg Phe He Arg Ala Asp Ser Gin Val Phe Leu
20 25 30
Phe Ala Asn Ser Lys Cys Lys Arg Tyr Phe His Asn Arg Leu Lys Pro
35 40 45
Ala Lys Leu Thr Trp Thr Ala Met Tyr Arg Lys Gin His Lys Lys Asp 50 55 60
He His Ala Glu Ala Val Lys Lys Arg Arg Arg Ala Thr Lys Lys Pro 65 70 75 80 Tyr Ser Arg Ser He Val Gly Ala Ser Leu Glu Val He Gin Lys Lys
85 90 95
Arg Ala Glu Lys Pro Glu Val Arg Asp Ala Ala Arg Glu Ala Ala Leu 100 105 110 Arg Glu He Lys Glu Arg He Lys Lys Thr Lys Asp Glu Lys Lys Ala 115 120 125
Lys Lys Ala Glu Val Ser Lys Ser Gin Lys Thr Gin Thr Lys Gly Ala
130 135 140
Val Gin Lys Gly Ser Lys Gly Pro Lys Leu Gly Gly Gly Gly Gly Lys 145 150 155 160
Arg
(2) INFORMATION FOR SEQ ID NO: 166: ■, i) SEQUENCE CHARACTERISTICS: (A.) LENGTH: 106 amino acids
(B) TYPE: amino acid
(C) STRANDEDNESS:
(D) TOPOLOGY: linear ii) MOLECULE TYPE: peptide ix! FEATURE:
(A) NAME/KEY: peptide
(B) LOCATION: I..106
(D) OTHER INFORMATION: / Ceres Seq. ID 2065749 xi) SEQUENCE DESCRIPTION: SEQ ID NO: 166: Met Tyr Arg Lys Gin His Lys Lys Asp He His Ala Glu Ala Val Lys 1 5 10 15
Lys A.rg Arg Arg Ala Thr Lys Lys Pro Tyr Ser Arg Ser He Val Gly
20 25 30
Ala Ser Leu Glu Val He Gin Lys Lys Arg Ala Glu Lys Pro Glu Val 35 40 45
Arg A.sp Ala Ala Arg Glu Ala Ala Leu Arg Glu He Lys Glu Arg He
50 55 60
Lys Lys Thr Lys Asp Glu Lys Lys Ala Lys Lys Ala Glu Val Ser Lys 65 70 75 80 Ser Gin Lys Thr Gin Thr Lys Gly Ala Val Gin Lys Gly Ser Lys Gly
85 90 95
Pro Lys Leu Gly Gly Gly Gly Gly Lys Arg 100 ' 105

Claims

CLAIMSWhat is claimed is:
1. An isolated nucleic acid molecule comprising a nucleic acid having a nucleotide sequence selected from the group consisting of
(i) a nucleotide sequence shown in SEQ TABLES 1 AND 2; (ii) a nucleotide sequence complementary to one shown in SEQ TABLES 1 AND 2;
(iii) a nucleotide sequence which is the reverse complement of one shown in SEQ TABLES 1 AND 2;
(iv) a nucleotide sequence capable of hybridizing to a nucleotide sequence shown in SEQ TABLES 1 AND 2;
(iv) a nucleotide sequence capable of hybridizing to a nucleotide sequence complementary to one shown in SEQ TABLES 1 AND 2;
(vi) a nucleotide sequence capable of hybridizing to a nucleotide sequence which is the reverse complement of one shown in SEQ TABLES 1 AND 2; whereby the hybridization in groups (iv) to (vi) allow said sequences to form a duplex at a temperature from about Tm-40°C to about Tm-48° C.
2. An isolated nucleic acid molecule according to claim 1 that comprises a complete open reading frame.
3. An isolated nucleic acid molecule according to claim 1 that functions as a promoter or as a 3' end termination sequence or as a regulator sequence influencing the transcription rate, the transcript stability or RNA translation rate in a host cell.
4. The isolated nucleic acid of claim 3, comprising a sequence selected from the group consisting of a TATA box sequence, a CAAT box sequence, a motif of GCAATCG or a transcription-factor binding sequence.
5.An isolated nucleic acid molecule comprising a nucleic acid sequence that encodes an amino acid sequence selected from the group consisting of the amino acid sequences shown in SEQ TABLES 1 AND 2, a complementary nucleotide sequence to said nucleic acid sequence that encodes said amino acid sequence selected from SEQ TABLES 1 AND 2, a reverse complementary nucleotide sequence to said nucleic acid sequence that encodes said amino acid sequence selected from SEQ TABLES 1 AND 2, and a nucleotide sequence that will hybridize to said nucleic acid sequence encoding an amino acid selected from SEQ TABLES 1 AND 2 or said complementary sequence under hybridization conditions providing Tm - 40°C to Tm - 48°C.
6. An isolated nucleic acid molecule comprising a nucleic acid sequence that encodes at least a part or a portion or a mutant or a fusion of an amino acid sequence selected from the group consisting of the amino acid sequences shown in SEQ TABLES 1 AND 2, a complementary nucleotide sequence to said nucleic acid sequence that encodes said part or portion or mutant or fusion of an amino acid sequence selected from SEQ TABLES 1 AND 2, a reverse complementary nucleotide sequence to said nucleic acid sequence that encodes said part or portion or mutant or fusion of an amino acid sequence selected from SEQ TABLES 1 AND 2, and a nucleotide sequence that will hybridize to said nucleic acid sequence that encodes said part or portion or mutant or fusion of an amino acid selected from SEQ TABLES 1 AND 2 or said complementary sequence or said reverse complementary sequence under hybridization conditions providing Tm - 40°C to Tm - 48°C.
7. An isolated nucleic acid molecule according to claim 1, having a nucleotide sequence selected from the group consisting of the nucleotide sequences shown in SEQ TABLES 1 AND 2, and a complementary nucleotide sequence to said nucleotide sequence selected from SEQ TABLES 1 AND 2.
8. A chimeric DNA construct comprising (a) a promoter sequence capable of driving gene expression in plant cells and operatively linked to (b) a structural gene comprising an DNA molecule according to any one of claims 1, 2, 5 and 7.
9. A chimeric DNA construct comprising (a) a promoter that is a nucleic acid molecule according to claim 3 or 4 operatively linked to (b) a structural gene and, optionally,
(c) an associated UTR.
10. An isolated DNA molecule comprising (a) a promoter sequence according to claim 3 or 4 and operatively linked to (b) a structural gene sequence according to any one of claims 1, 2, 5, 6 and 7.
11. A promoter according to claim 10, wherein said promoter is a specific promoter.
12. A promoter according to claim 11, wherein said promoter is a seed-specific promoter, an embryo-specific promoter, an ovule-specific promoter, a tapetum-specific promoter or a root-specific promoter.
13. A host cell transformed with a polynucleotide comprising the isolated nucleic acid molecule according to claim 1.
14. An isolated polypeptide comprising an amino acid sequence encoded by a polynucleotide sequence shown in SEQ TABLES 1 AND 2, or one that is at least 75% identical thereto.
15. An isolated polypeptide according to claim 14, that is at least 85% identical to said amino acid sequence.
16. An isolated polypeptide, according to claim 15, that is at least 90% identical to said amino acid sequence.
17. A polynucleotide comprising a first polynucleotide sequence from SEQ TABLES 1 AND 2 or a fragment thereof, wherein said_first sequence is capable of regulating transcription or translation of second a polynucleotide comprising a coding sequence in a host cell or in vi tro system wherein the first and second polynucleotides are operatively linked.
18. The first polynucleotide of claim 17, which is capable of regulating transcription or translation in an in vi tro system.
19. The first polynucleotide of claim 17, which is capable of regulating transcription or translation in a host cell.
20. The polynucleotide of claim 19, wherein said host cell is a plant cell.
21. A host cell of claim 13, wherein said isolated nucleic acid comprises a promoter and operatively linked structural gene and further wherein said promoter and structural gene are not heterologous to each other and are exogenous to the host cell genome.
22. A method of introducing an isolated nucleic acid into a host cell comprising:
(a) providing an isolated nucleic acid of any of claims 1-12; (b) contacting said isolated nucleic acid with said host cell under conditions that permit insertion of said nucleic acid into said host cell.
23. A method of producing a polypeptide of any one of claims 14-16 comprising:
(a) providing a host cell of claim 13;
(b) culturing said host cell under conditions that permit transcription and translation of said structural gene to produce a polypeptide; and
(c) isolating said polypeptide.
24. An antibody capable of binding to a polypeptide of any one of claims 14-16.
25. An isolated nucleic acid comprising a promoter of a gene wherein said gene comprises a nucleic acid having the nucleotide sequence of claim 1.
26. An isolated polypeptide comprising an amino acid sequence selected from SEQ TABLES 1 AND 2, or one that is at least 75% identical thereto.
27. The isolated polypeptide according to Claim 26 that is at least 85% identical thereto.
28. The isolated polypeptide according to claim 26 that is at least 90% identical thereto.
EP00901405A 1999-01-08 2000-01-07 Sequence-determined dna fragments and corresponding polypeptides encoded thereby Ceased EP1141301A4 (en)

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AU2003247266A1 (en) 2002-08-01 2004-02-23 Nuevolution A/S Multi-step synthesis of templated molecules
WO2004028682A2 (en) 2002-09-27 2004-04-08 Carlsberg A/S Spatially encoded polymer matrix
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