EP1135119A4 - Glucose and lipid lowering compounds - Google Patents

Glucose and lipid lowering compounds

Info

Publication number
EP1135119A4
EP1135119A4 EP99957542A EP99957542A EP1135119A4 EP 1135119 A4 EP1135119 A4 EP 1135119A4 EP 99957542 A EP99957542 A EP 99957542A EP 99957542 A EP99957542 A EP 99957542A EP 1135119 A4 EP1135119 A4 EP 1135119A4
Authority
EP
European Patent Office
Prior art keywords
glucose
lipid lowering
lowering compounds
compounds
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99957542A
Other languages
German (de)
French (fr)
Other versions
EP1135119A1 (en
Inventor
Dilip Wagle
Sheng Ding Fang
Ihor Terleckyj
John Resek
Jack Egan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synvista Therapeutics Inc
Original Assignee
Alteon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alteon Inc filed Critical Alteon Inc
Publication of EP1135119A1 publication Critical patent/EP1135119A1/en
Publication of EP1135119A4 publication Critical patent/EP1135119A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
EP99957542A 1998-11-12 1999-11-10 Glucose and lipid lowering compounds Withdrawn EP1135119A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US190507 1994-02-02
US19050798A 1998-11-12 1998-11-12
US19735298A 1998-11-20 1998-11-20
US197352 1998-11-20
PCT/US1999/026563 WO2000027388A1 (en) 1998-11-12 1999-11-10 Glucose and lipid lowering compounds

Publications (2)

Publication Number Publication Date
EP1135119A1 EP1135119A1 (en) 2001-09-26
EP1135119A4 true EP1135119A4 (en) 2004-11-03

Family

ID=26886182

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99957542A Withdrawn EP1135119A4 (en) 1998-11-12 1999-11-10 Glucose and lipid lowering compounds

Country Status (8)

Country Link
EP (1) EP1135119A4 (en)
JP (1) JP2002529409A (en)
KR (1) KR20010080428A (en)
AU (1) AU761878B2 (en)
CA (1) CA2350213A1 (en)
MX (1) MXPA01004830A (en)
NZ (1) NZ511572A (en)
WO (1) WO2000027388A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2286451A1 (en) * 1999-10-14 2001-04-14 Grant A. Mitchell Hormone-sensitive lipase mediated male infertility
EP1636201A1 (en) * 2003-06-12 2006-03-22 Novo Nordisk A/S Para-substituted phenyl carbamates as inhibitors of hormone sensitive lipase
WO2004111006A1 (en) * 2003-06-12 2004-12-23 Novo Nordisk A/S Para-subtituted phenyl carbamates as inhibitors of hormone sensitive lipase
US7951406B2 (en) 2004-12-23 2011-05-31 Caroline Van Haaften Therapeutic compounds isolated from Calomeria amaranthoides
AU2005317748B8 (en) * 2004-12-23 2011-07-21 Caroline Van Haaften Therapeutic compounds isolated from Calomeria amaranthoides
CN114886889A (en) * 2022-04-27 2022-08-12 清华大学 Application of alantolactone or derivatives thereof in preparation of medicines, health products or foods for preventing or treating obesity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0597107A1 (en) * 1991-10-17 1994-05-18 Shionogi & Co., Ltd. Lignan analog, production thereof, and hypolipidemic drug

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5917084A (en) * 1996-07-03 1999-06-29 Millennium Pharmaceuticals, Inc. Antifungal agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0597107A1 (en) * 1991-10-17 1994-05-18 Shionogi & Co., Ltd. Lignan analog, production thereof, and hypolipidemic drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0027388A1 *

Also Published As

Publication number Publication date
JP2002529409A (en) 2002-09-10
CA2350213A1 (en) 2000-05-18
MXPA01004830A (en) 2002-09-18
AU1522600A (en) 2000-05-29
WO2000027388A1 (en) 2000-05-18
AU761878B2 (en) 2003-06-12
EP1135119A1 (en) 2001-09-26
KR20010080428A (en) 2001-08-22
NZ511572A (en) 2003-06-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20010531

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: EGAN, JACK

Inventor name: RESEK, JOHN

Inventor name: TERLECKYJ, IHOR

Inventor name: FANG, SHENG, DING

Inventor name: WAGLE, DILIP

A4 Supplementary search report drawn up and despatched

Effective date: 20040917

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20041204