EP1129178A4 - A sensitive screening system for envelope-defective recombinant virus - Google Patents

A sensitive screening system for envelope-defective recombinant virus

Info

Publication number
EP1129178A4
EP1129178A4 EP99962650A EP99962650A EP1129178A4 EP 1129178 A4 EP1129178 A4 EP 1129178A4 EP 99962650 A EP99962650 A EP 99962650A EP 99962650 A EP99962650 A EP 99962650A EP 1129178 A4 EP1129178 A4 EP 1129178A4
Authority
EP
European Patent Office
Prior art keywords
envelope
recombinant virus
screening system
defective recombinant
sensitive screening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99962650A
Other languages
German (de)
French (fr)
Other versions
EP1129178A1 (en
Inventor
Anatoly Bukovsky
Luigi Naldini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Genesys Inc
Original Assignee
Cell Genesys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Genesys Inc filed Critical Cell Genesys Inc
Publication of EP1129178A1 publication Critical patent/EP1129178A1/en
Publication of EP1129178A4 publication Critical patent/EP1129178A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99962650A 1998-11-13 1999-11-12 A sensitive screening system for envelope-defective recombinant virus Withdrawn EP1129178A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10816898P 1998-11-13 1998-11-13
PCT/US1999/024017 WO2000029557A1 (en) 1998-11-13 1999-11-12 A sensitive screening system for envelope-defective recombinant virus
US108168P 2008-10-24

Publications (2)

Publication Number Publication Date
EP1129178A1 EP1129178A1 (en) 2001-09-05
EP1129178A4 true EP1129178A4 (en) 2002-08-21

Family

ID=22320692

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99962650A Withdrawn EP1129178A4 (en) 1998-11-13 1999-11-12 A sensitive screening system for envelope-defective recombinant virus

Country Status (5)

Country Link
EP (1) EP1129178A4 (en)
JP (1) JP2002530070A (en)
AU (1) AU1905200A (en)
CA (1) CA2350124A1 (en)
WO (1) WO2000029557A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078987A1 (en) * 1999-06-22 2000-12-28 Dnavec Research Inc. Vector for expressing two foreign genes
DK1616012T3 (en) 2003-04-24 2008-04-21 San Raffaele Centro Fond Lentiviral vectors bearing synthetic bidirectional promoters and their applications

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629469B1 (en) * 1988-03-31 1990-12-21 Pasteur Institut DEFECTIVE RECOMBINANT RETROVIRUS, ITS APPLICATION TO THE INTEGRATION OF CODING SEQUENCES FOR PROTEINS DETERMINED IN THE GENOME OF CORRESPONDING WILD RETROVIRUS INFECTIOUS CELLS AND RECOMBINANT DNA FOR THE PRODUCTION OF THIS RECOMBINANT RETROVIRUS
US5614404A (en) * 1988-06-10 1997-03-25 Theriod Biologics, Incorporated Self-assembled, defective, non-self-propagating lentivirus particles
AU6075190A (en) * 1989-06-30 1991-01-17 Regents Of The University Of California, The Retrovirus detection
US5591579A (en) * 1993-12-21 1997-01-07 Washington University Indicator cell line for detecting RNA viruses and method therefor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NALDINI L ET AL: "EFFICIENT TRANSFER, INTEGRATION, AND SUSTAINED LONG-TERM EXPRESSIONOF THE TRANSGENE IN ADULT RAT BRAINS INJECTED WITH A LENTIVIRAL VECTOR", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, October 1996 (1996-10-01), pages 11382 - 11388, XP002917173, ISSN: 0027-8424 *
ORY D S ET AL: "A STABLE HUMAN-DERIVED PACKAGING CELL LINE FOR PRODUCTION OF HIGH TITER RETROVIRUS/VESICULAR STOMATITIS VIRUS G PSEUDOTYPES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 21, 15 October 1996 (1996-10-15), pages 11400 - 11406, XP002030515, ISSN: 0027-8424 *
RIVIERE ISABELLE ET AL: "Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 92, no. 15, 1995, 1995, pages 6733 - 6737, XP002202961, ISSN: 0027-8424 *
See also references of WO0029557A1 *

Also Published As

Publication number Publication date
AU1905200A (en) 2000-06-05
WO2000029557A1 (en) 2000-05-25
JP2002530070A (en) 2002-09-17
EP1129178A1 (en) 2001-09-05
CA2350124A1 (en) 2000-05-25

Similar Documents

Publication Publication Date Title
GB9824544D0 (en) Screening system
EP0967484A4 (en) Methods for detecting or assaying virus
GB2335639B (en) Sorting system
IL132134A0 (en) Method for inactivating a virus
HK1033786A1 (en) A secure messging system
GB2346475B (en) Electronic edge detection system
AU5706798A (en) Program signal blocking system
GB0026938D0 (en) Sorting system
GB2325978B (en) Sensing system
GB9707996D0 (en) Screening
EP1010094A4 (en) Compound screening system
AU1773099A (en) Materials for virus capture
EP1129178A4 (en) A sensitive screening system for envelope-defective recombinant virus
HU9800113D0 (en) Transgenic virus
GB2327897B (en) Screening system
GB2339947B (en) Bridge protection system
AU5957498A (en) Program signal blocking system
HUP0003511A3 (en) Hepatitis b virus polypeptides
GB2330094B (en) Sorting system
GB9825053D0 (en) Recombinant virus
ZA985361B (en) Particulate material separation
GB9723430D0 (en) Screening system
ZA984772B (en) Screening system
GB2334802B (en) Bridge protection system
IL140120A0 (en) Immunomodulator polypeptide zsig57

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010515

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20020708

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CELL GENESYS, INC.

17Q First examination report despatched

Effective date: 20050628

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20060601