EP1127156A4 - Regulation of nitric oxide synthase activity - Google Patents

Regulation of nitric oxide synthase activity

Info

Publication number
EP1127156A4
EP1127156A4 EP99957226A EP99957226A EP1127156A4 EP 1127156 A4 EP1127156 A4 EP 1127156A4 EP 99957226 A EP99957226 A EP 99957226A EP 99957226 A EP99957226 A EP 99957226A EP 1127156 A4 EP1127156 A4 EP 1127156A4
Authority
EP
European Patent Office
Prior art keywords
regulation
nitric oxide
oxide synthase
synthase activity
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99957226A
Other languages
German (de)
French (fr)
Other versions
EP1127156A1 (en
Inventor
David Ian Stapleton
Zhiping Chen
Belinda Joyce Michell
Bruce Ernest Kemp
Kenneth Ian Mitchelhill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Vincents Institute of Medical Research
Original Assignee
St Vincents Institute of Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Vincents Institute of Medical Research filed Critical St Vincents Institute of Medical Research
Publication of EP1127156A1 publication Critical patent/EP1127156A1/en
Publication of EP1127156A4 publication Critical patent/EP1127156A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99957226A 1998-11-06 1999-11-05 Regulation of nitric oxide synthase activity Withdrawn EP1127156A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP697698 1998-11-06
AUPP6976A AUPP697698A0 (en) 1998-11-06 1998-11-06 Regulation of enzyme activity
PCT/AU1999/000968 WO2000028076A1 (en) 1998-11-06 1999-11-05 Regulation of nitric oxide synthase activity

Publications (2)

Publication Number Publication Date
EP1127156A1 EP1127156A1 (en) 2001-08-29
EP1127156A4 true EP1127156A4 (en) 2003-05-28

Family

ID=3811190

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99957226A Withdrawn EP1127156A4 (en) 1998-11-06 1999-11-05 Regulation of nitric oxide synthase activity

Country Status (4)

Country Link
EP (1) EP1127156A4 (en)
JP (1) JP2004537251A (en)
AU (1) AUPP697698A0 (en)
WO (1) WO2000028076A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR972801A0 (en) * 2001-12-21 2002-01-24 St. Vincent's Institute Of Medical Research Oligosaccharide binding domains
WO2010103040A1 (en) * 2009-03-10 2010-09-16 INSERM (Institut National de la Santé et de la Recherche Médicale) 5'-adenosine monophosphate-activated protein kinase (ampk) activators for treating pulmonary hypertension
CA2861543C (en) 2012-01-18 2022-05-31 Governing Council Of The University Of Toronto Novel peptides and methods and uses thereof for preventing retinal disorders
JP2022543056A (en) * 2019-07-29 2022-10-07 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ Compositions and methods for promoting wound healing

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026657A1 (en) * 1997-11-25 1999-06-03 Musc Foundation For Research Development Inhibitors of nitric oxide synthase

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
MATSUBARA MAMORU ET AL: "Interaction of calmodulin-binding domain peptides of nitric oxide synthase with membrane phospholipids: Regulation by protein phosphorylation and Ca-2+- calmodulin.", BIOCHEMISTRY, vol. 35, no. 46, 1996, pages 14651 - 14658, XP002236723, ISSN: 0006-2960 *
MICHEL THOMAS ET AL: "Nitric oxide synthases: Which, where, how and why?", JOURNAL OF CLINICAL INVESTIGATION, vol. 100, no. 9, 1 November 1997 (1997-11-01), pages 2146 - 2152, XP002236722, ISSN: 0021-9738 *
See also references of WO0028076A1 *
VENEMA RICHARD C ET AL: "Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 11, 1996, pages 6435 - 6440, XP002236724, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2000028076A1 (en) 2000-05-18
JP2004537251A (en) 2004-12-16
EP1127156A1 (en) 2001-08-29
AUPP697698A0 (en) 1998-12-03

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20010525

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12Q 1/48 B

Ipc: 7C 12Q 1/26 A

A4 Supplementary search report drawn up and despatched

Effective date: 20030416

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Effective date: 20050503