EP1124985A4 - Biomarkers for oxidative stress - Google Patents

Biomarkers for oxidative stress

Info

Publication number
EP1124985A4
EP1124985A4 EP99971864A EP99971864A EP1124985A4 EP 1124985 A4 EP1124985 A4 EP 1124985A4 EP 99971864 A EP99971864 A EP 99971864A EP 99971864 A EP99971864 A EP 99971864A EP 1124985 A4 EP1124985 A4 EP 1124985A4
Authority
EP
European Patent Office
Prior art keywords
biomarkers
oxidative stress
oxidative
stress
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP99971864A
Other languages
German (de)
French (fr)
Other versions
EP1124985A1 (en
Inventor
Joseph M Kinkade Jr
Raymond Shapira
Peter E Jensen
Ngoc-Anh Le
Jan Pohl
W Virgil Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
Original Assignee
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Publication of EP1124985A1 publication Critical patent/EP1124985A1/en
Publication of EP1124985A4 publication Critical patent/EP1124985A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
EP99971864A 1998-11-06 1999-11-05 Biomarkers for oxidative stress Ceased EP1124985A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10740498P 1998-11-06 1998-11-06
US107404P 1998-11-06
PCT/US1999/026133 WO2000028072A1 (en) 1998-11-06 1999-11-05 Biomarkers for oxidative stress

Publications (2)

Publication Number Publication Date
EP1124985A1 EP1124985A1 (en) 2001-08-22
EP1124985A4 true EP1124985A4 (en) 2003-01-15

Family

ID=22316499

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99971864A Ceased EP1124985A4 (en) 1998-11-06 1999-11-05 Biomarkers for oxidative stress

Country Status (4)

Country Link
EP (1) EP1124985A4 (en)
AU (1) AU1243500A (en)
CA (1) CA2348685A1 (en)
WO (1) WO2000028072A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040029208A1 (en) * 2000-05-30 2004-02-12 Ravn Helle Weber Assay method and kit for testing biological material for exposure to stress using biomarkers
DE10051983A1 (en) 2000-10-20 2002-06-13 Beate Kehrel Medicaments useful e.g. for preventing thrombosis, inhibiting transplant rejection or treating chronic inflammatory reactions comprises agents inhibiting binding of oxidized proteins to CD36,
JP4881535B2 (en) * 2000-10-20 2012-02-22 ハンブルガー・シュティフトゥング・ツーア・フェルデルング・フォン・ヴィッセンシャフト・ウント・クルトゥーア Oxidized proteins and their biological activity, the mechanism of activity, the use of the protein and therapeutic and diagnostic methods derived from its inhibition
EP1507548B1 (en) 2002-05-27 2014-10-01 CanImGuide Therapeutics AB Method for determining immune system affecting compounds
GB0329288D0 (en) 2003-12-18 2004-01-21 Inverness Medical Switzerland Monitoring method and apparatus
SE0402536D0 (en) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
EP1875246B1 (en) 2005-04-15 2016-10-05 CanImGuide Therapeutics AB Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
EP2226334A3 (en) 2007-05-08 2010-12-29 CanImGuide Therapeutics AB Immunoregulatory structures from normally occuring proteins
JP2010183843A (en) * 2009-02-10 2010-08-26 National Institute Of Advanced Industrial Science & Technology Antibody against oxidation type polypeptide containing oxidized sulfur-containing amino acid residue
WO2012018535A2 (en) 2010-07-26 2012-02-09 Wellness Indicators, Inc. Wellness panel
WO2014201451A1 (en) * 2013-06-14 2014-12-18 Wellmetris Llc Stress and inflammation biomarker urine panel for dairy cows and beef cattle
AU2013251276A1 (en) 2013-07-18 2015-02-05 Northern Sydney Local Health District Biomarkers of oxidative stress

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004311A1 (en) * 1994-08-03 1996-02-15 University Of Alabama At Birmingham Research Foundation Monoclonal antibody to nitrotyrosine, methods for diagnosis and methods for treatment of disease
WO1997011371A1 (en) * 1995-09-19 1997-03-27 Cytochem, Inc. Detection and quantitation of 8-oh-adenine using monoclonal antibodies
WO1998012561A1 (en) * 1996-09-20 1998-03-26 Atherogenics, Inc. Diagnostics for and mediators of inflammatory disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859613A (en) * 1986-11-12 1989-08-22 Lawrence David A Immunoassays for glutathione and antibodies useful therein
US5508031A (en) * 1986-11-21 1996-04-16 Cetus Oncology Corporation Method for treating biological damage using a free-radial scavenger and interleukin-2
WO1992022668A1 (en) * 1991-06-14 1992-12-23 Vanderbilt University Method and compositions to assess oxidative stress in vivo
US5589337A (en) * 1992-07-06 1996-12-31 The President And Fellows Of Harvard College Methods and diagnostic kits for determining toxicity utilizing bacterial stress promoters fused to reporter genes
US5605826A (en) * 1994-06-10 1997-02-25 Panorama Research, Inc. 24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
US5814300A (en) * 1995-03-03 1998-09-29 Cephalon, Inc. Gene-targeted non-human mammals deficient in the SOD-1 gene

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004311A1 (en) * 1994-08-03 1996-02-15 University Of Alabama At Birmingham Research Foundation Monoclonal antibody to nitrotyrosine, methods for diagnosis and methods for treatment of disease
WO1997011371A1 (en) * 1995-09-19 1997-03-27 Cytochem, Inc. Detection and quantitation of 8-oh-adenine using monoclonal antibodies
WO1998012561A1 (en) * 1996-09-20 1998-03-26 Atherogenics, Inc. Diagnostics for and mediators of inflammatory disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AHMAD J ET AL: "DETECTION OF OXIDATIVE DNA DAMAGE BY A MONOCLONAL ANTIBODY: ROLE OF LYSYL RESIDUES IN ANTIGEN BINDING", IMMUNOLOGY LETTERS, AMSTERDAM, NL, vol. 62, no. 2, June 1998 (1998-06-01), pages 87 - 92, XP001118007, ISSN: 0165-2478 *
See also references of WO0028072A1 *

Also Published As

Publication number Publication date
WO2000028072A1 (en) 2000-05-18
WO2000028072A9 (en) 2000-09-21
AU1243500A (en) 2000-05-29
EP1124985A1 (en) 2001-08-22
CA2348685A1 (en) 2000-05-18

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