EP1117690A4 - Polymeric hemoglobin mutants - Google Patents

Polymeric hemoglobin mutants

Info

Publication number
EP1117690A4
EP1117690A4 EP99953002A EP99953002A EP1117690A4 EP 1117690 A4 EP1117690 A4 EP 1117690A4 EP 99953002 A EP99953002 A EP 99953002A EP 99953002 A EP99953002 A EP 99953002A EP 1117690 A4 EP1117690 A4 EP 1117690A4
Authority
EP
European Patent Office
Prior art keywords
polymeric hemoglobin
hemoglobin mutants
mutants
polymeric
hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99953002A
Other languages
German (de)
French (fr)
Other versions
EP1117690A1 (en
Inventor
Clara Fronticelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Temple University of Commonwealth System of Higher Education
Original Assignee
Temple University of Commonwealth System of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temple University of Commonwealth System of Higher Education filed Critical Temple University of Commonwealth System of Higher Education
Publication of EP1117690A1 publication Critical patent/EP1117690A1/en
Publication of EP1117690A4 publication Critical patent/EP1117690A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP99953002A 1998-10-01 1999-09-30 Polymeric hemoglobin mutants Withdrawn EP1117690A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10264098P 1998-10-01 1998-10-01
US102640P 1998-10-01
PCT/US1999/022756 WO2000018802A1 (en) 1998-10-01 1999-09-30 Polymeric hemoglobin mutants

Publications (2)

Publication Number Publication Date
EP1117690A1 EP1117690A1 (en) 2001-07-25
EP1117690A4 true EP1117690A4 (en) 2004-10-27

Family

ID=22290901

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99953002A Withdrawn EP1117690A4 (en) 1998-10-01 1999-09-30 Polymeric hemoglobin mutants

Country Status (4)

Country Link
EP (1) EP1117690A4 (en)
AU (1) AU6504199A (en)
CA (1) CA2344604A1 (en)
WO (1) WO2000018802A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005041898A2 (en) 2003-10-30 2005-05-12 Temple University Of The Commonwealth System Of Higher Education Blood substitutes
GB201721503D0 (en) 2017-12-20 2018-01-31 Univ Essex Modified globin proteins

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003820A1 (en) * 1993-07-30 1995-02-09 The Uab Research Foundation Transgenic, cross-linked hemoglobin
WO1995004744A1 (en) * 1993-08-11 1995-02-16 Dnx Corporation Production of human hemoglobin in transgenic pigs
US5599907A (en) * 1989-05-10 1997-02-04 Somatogen, Inc. Production and use of multimeric hemoglobins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545727A (en) * 1989-05-10 1996-08-13 Somatogen, Inc. DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599907A (en) * 1989-05-10 1997-02-04 Somatogen, Inc. Production and use of multimeric hemoglobins
US5739011A (en) * 1989-05-10 1998-04-14 Somatogen, Inc. DNA for the production of multimeric hemoglobins
WO1995003820A1 (en) * 1993-07-30 1995-02-09 The Uab Research Foundation Transgenic, cross-linked hemoglobin
WO1995004744A1 (en) * 1993-08-11 1995-02-16 Dnx Corporation Production of human hemoglobin in transgenic pigs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FRONTICELLI CLARA ET AL: "Molecular engineering of a polymer of tetrameric hemoglobins", PROTEINS, vol. 44, no. 3, 15 August 2001 (2001-08-15), pages 212 - 222, XP002294066, ISSN: 0887-3585 *
MORLÉ F ET AL: "A new alpha chain variant Hb Sallanches [alpha 2 104(G11) Cys-->Tyr] associated with HbH disease in one homozygous patient.", BRITISH JOURNAL OF HAEMATOLOGY. NOV 1995, vol. 91, no. 3, November 1995 (1995-11-01), pages 608 - 611, XP008034641, ISSN: 0007-1048 *
See also references of WO0018802A1 *

Also Published As

Publication number Publication date
WO2000018802A1 (en) 2000-04-06
AU6504199A (en) 2000-04-17
EP1117690A1 (en) 2001-07-25
CA2344604A1 (en) 2000-04-06

Similar Documents

Publication Publication Date Title
DE59912562D1 (en) Indolyl-3-glyoxylsäure-derivate mit antitumorwirkung
GB2343496B (en) Sliding member
DE59912932D1 (en) Arylphenylsubstituierte cyclische ketoenole
DE59912303D1 (en) Arylphenylsubstituierte cyclische ketoenole
AU136994S (en) Section
GB9925638D0 (en) No title
GB2344605B (en) Sliding member
DE69924297D1 (en) Orthopädische prothese mit zementkompressionsring
DE59903023D1 (en) Perorale wirkstoff-suspension
IL134357A0 (en) Joiner
DE60042897D1 (en) Photovervielfacherröhre
PL342472A1 (en) Pelletised polymeric preparations
DE59900495D1 (en) Multimetalloxidmassen
DE59900471D1 (en) Inchbremseinrichtung
EP1117690A4 (en) Polymeric hemoglobin mutants
AU135757S (en) Joiner
DE59905941D1 (en) Methoximinophenylessigsäureamide
DE59911094D1 (en) Tryptase-inhibitoren
GB9826367D0 (en) Organism
GB9807430D0 (en) Rapid Floar
PL337368A1 (en) 13-dihydro-3'-azaridinoantracyclins
TW335058U (en) Side groove
CA84573S (en) Sungalsses
CA85048S (en) Bedboard
AU136440S (en) Section

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010402

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20040914

17Q First examination report despatched

Effective date: 20050228

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050712