EP1115353A1 - Mechanical heart valve assembly with super-elastic lock wire - Google Patents
Mechanical heart valve assembly with super-elastic lock wireInfo
- Publication number
- EP1115353A1 EP1115353A1 EP99949874A EP99949874A EP1115353A1 EP 1115353 A1 EP1115353 A1 EP 1115353A1 EP 99949874 A EP99949874 A EP 99949874A EP 99949874 A EP99949874 A EP 99949874A EP 1115353 A1 EP1115353 A1 EP 1115353A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- lock wire
- stiffening ring
- orifice
- lock
- wire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
Definitions
- the present invention relates to a mechanical heart valve and method for manufacturing the same.
- Mechanical heart valves are used to replace native valves which no longer function properly due to disease or other factors.
- Mechanical valves typically include an orifice having one or more occulders, which regulate blood flow.
- mechanical valves typically include a stiffening ring that helps the valve assembly resist the compressive annular loads to which it is exposed when implanted. The stiffening ring can be made integral to the valve orifice or mechanically attached to the valve orifice.
- One coupling mechanism includes a lock wire.
- a lock wire For example, the family of Sulzer
- Carbomedics Prosthetic Heart Valves utilize a titanium lock wire positioned in grooves on the outer wall of the orifice and inner wall of the stiffening ring.
- a window in the stiffening ring allows insertion of the lock wire when the groove on the orifice is aligned with the groove on the stiffening ring.
- a prior art valve of this type is described in Walker et al., U.S. Patent 5,397,346.
- the stiffening ring is incorporated with the sewing cuff. Therefore, in order to perform the mechanical attachment of orifice and ring, the cuff must be cut or otherwise partially disassembled to allow the lock wire to be passed through the window of the stiffening ring and into the aligned grooves. Once the lock wire is inserted, the cuff must be stitched closed again. This process of cutting and repairing the sewing cuff is time consuming. Further, this process leads to rejection of valve assemblies due to visual discrepancies caused by the cut/sew process.
- the present invention is directed toward a mechanical heart valve assembly.
- the mechanical heart valve assembly includes a generally annular valve orifice.
- the outer surface of the valve orifice has a circumferential lock wire groove.
- a generally annular valve support ring surrounds at least a portion of the valve orifice.
- the support ring includes an inner surface with a circumferential lock wire groove.
- the orifice lock wire groove and support ring lock wire groove are positioned generally opposite each other.
- a lock wire is positioned in the grooves, operably coupling the orifice and support ring.
- the lock wire comprises a super-elastic material.
- the lock wire comprises nickel-titanium alloy, e.g., SE508 alloy.
- the lock wire includes a first and a second end and is generally "C" shaped. In one embodiment, the distance between the first and second ends of the lock wire is about 0.115 inches. In one embodiment, the lock wire has a cross-sectional diameter of about 0.0135 inches.
- the support ring includes a window for receiving the wire.
- a sewing cuff is disposed circumferentially about at least a portion of the support ring, covering the window.
- the present invention is directed toward a method of manufacturing a mechanical heart valve assembly.
- the mechanical heart valve assembly includes an orifice, a stiffening ring, and a lock wire.
- the lock wire is formed into a super-elastic "C" shape.
- the stiffening ring is aligned with the orifice so that the stiffening ring surrounds at least a portion of the orifice and so that a lock wire groove on an inner wall of the stiffening ring is generally aligned with a lock wire groove on an outer wall of the orifice.
- a first end of the lock wire is inserted through a window in the stiffening ring and into the generally aligned lock wire grooves until all of the lock wire is seated in the lock wire grooves.
- a sewing cuff is positioned circumferentially about at least a portion of the stiffening ring. The first end of the lock wire pierces the sewing cuff before it is inserted into the window of the support ring.
- Figure 2 is bottom view of a stiffening ring
- Figure 3 is a top view of a lock wire
- Figure 4 is a side, cross-sectional view of a lock wire.
- FIG. 1 An exploded view of a mechanical heart valve assembly is shown in Figure 1.
- a generally annular valve orifice 2 includes an outer wall 4 having a circumferential lock-wire groove 6.
- Occluders 8 are disposed within valve orifice 2 and coupled with inner wall 10.
- the embodiment shown in Figure 1 includes two occluders 8. Other embodiments may include one occluder or three or more occluders.
- a generally annular stiffening or support ring 12 includes an outer wall 14 (Fig. 2) and an inner wall 16.
- sewing cuff 20 includes a seating lip or flange 18 that is useful for seating the heart valve assembly in a valve annulus.
- Other embodiments include a sewing cuff 20 without a flange.
- the sewing cuff 20 is positioned circumferentially around outer wall 14. When the heart valve assembly is seated in a native valve annulus, sutures are passed through the sewing cuff 20 and the surrounding annulus tissue to securely fix the valve assembly in place.
- the sewing cuff 20 is made from polyester knit, PTFE knit, ePTFE knit, or other biocompatible material that promotes tissue growth about the valve assembly, providing a long-term, secure attachment.
- Stiffening ring 12 also includes window 22 extending from outer wall 14 to inner wall 16.
- a circumferential lock-wire groove 24 on inner wall 16 intersects window 22, as shown in Figure
- Lock wire 26 mechanically couples orifice 2 and stiffening ring 12 as described below.
- Lock wire 26 is made from a biocompatible, super-elastic material.
- lock wire 26 is made from a nickel titanium alloy, commonly known as nitinol.
- nickel titanium alloy commonly known as nitinol.
- nitinol One example of a suitable alloy is
- SE508 alloy available from Nitinol Devices & Components, Inc., Fremont, California.
- the pre-formed of lock wire 26 is generally in the shape of a C .
- the length of wire 26 is selected for the specific size of the valve being used, and the gap 28 in lock wire 26, which defines the open part of the "C" shape, is about 0.115 inches.
- a valve sized for a 29-mm annulus has a lock wire with a length of about 3.0203 inches and gap of about 0.115 inches.
- the cross-sectional shape of lock wire 26 is generally circular with a diameter of about 0.0135 inches +/- .0005 inches.
- lock wire 26 is pre-formed into a "C" shaped ring of the appropriate diameter for the selected valve size. This is accomplished by wrapping the generally straight lock wire around a rod of appropriate diameter and annealing the lock wire into the desired "C" shape. Other methods for working with super-elastic materials may also be used.
- Stiffening ring 12 is disposed about orifice 2 so that lock wire grooves 6, 24 are generally aligned.
- One end 30 or 32 of lock wire 26 is used to pierce cuff 20. The end then passes through cuff 20 into window 22 of stiffening ring 12. Lock wire 26 then slides into the generally opposed grooves 6, 24 and passes around the circumference of both stiffening ring 12 and orifice 2 in grooves 6, 24. When lock wire 26 is fully inserted in grooves 6, 24 it returns to its pre-formed "C" shape, providing a secure mechanical coupling between orifice 2 and stiffening ring 12. Since cuff 20 has been pierced by wire having a small diameter, e.g., 0.0135 inches, there is no significant damage to cuff 20 that might require repair.
- lock wire 26 Due to the super-elastic characteristics of lock wire 26, it will retain its shape within the physiological temperature range commonly found in an implantation. In the embodiment using the SE508 alloy, the lock wire will retain its shape to temperatures as low as 20 degrees Celsius. Further, the lock wire will retain its shape after multiple steam sterilizations to which it may be exposed during manufacture and prior to implantation.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Temperature-Responsive Valves (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/161,045 US6200341B1 (en) | 1998-09-25 | 1998-09-25 | Mechanical heart valve assembly with super-elastic lock wire |
US161045 | 1998-09-25 | ||
PCT/US1999/022255 WO2000018334A1 (en) | 1998-09-25 | 1999-09-24 | Mechanical heart valve assembly with super-elastic lock wire |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1115353A1 true EP1115353A1 (en) | 2001-07-18 |
EP1115353B1 EP1115353B1 (en) | 2008-05-28 |
Family
ID=22579573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99949874A Expired - Lifetime EP1115353B1 (en) | 1998-09-25 | 1999-09-24 | Mechanical heart valve assembly with super-elastic lock wire |
Country Status (6)
Country | Link |
---|---|
US (1) | US6200341B1 (en) |
EP (1) | EP1115353B1 (en) |
JP (1) | JP2002525170A (en) |
CA (1) | CA2345643C (en) |
DE (1) | DE69938836D1 (en) |
WO (1) | WO2000018334A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6893459B1 (en) | 2000-09-20 | 2005-05-17 | Ample Medical, Inc. | Heart valve annulus device and method of using same |
GR1004327B (en) * | 2002-08-08 | 2003-09-05 | Καnταρτζης Μιχαηλ | Dividable mechanical heart valve device |
WO2005070342A1 (en) * | 2004-01-22 | 2005-08-04 | Australian Surgical Design & Manufacture Pty Ltd | Heart valve |
US7875069B2 (en) * | 2006-09-21 | 2011-01-25 | Boston Scientific Scimed, Inc. | Stent with support element |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US9801719B2 (en) * | 2014-08-15 | 2017-10-31 | Edwards Lifesciences Corporation | Annulus rings with suture clips |
CA3218747A1 (en) | 2015-12-10 | 2017-06-15 | Mvrx, Inc. | Devices, systems, and methods for reshaping a heart valve annulus |
EP3407835A4 (en) | 2016-01-29 | 2019-06-26 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
JP2019535415A (en) | 2016-11-21 | 2019-12-12 | ニオバスク ティアラ インコーポレイテッド | Method and system for rapid retraction of a transcatheter heart valve delivery system |
DE102017107705A1 (en) * | 2017-04-10 | 2018-10-11 | Gemü Gebr. Müller Apparatebau Gmbh & Co. Kommanditgesellschaft | Device for arranging an electronic data carrier on a component of a fluid power system |
EP3672530A4 (en) | 2017-08-25 | 2021-04-14 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
JP7430732B2 (en) | 2019-03-08 | 2024-02-13 | ニオバスク ティアラ インコーポレイテッド | Retrievable prosthesis delivery system |
CA3135753C (en) | 2019-04-01 | 2023-10-24 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
CA3136334A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
EP3972673A4 (en) | 2019-05-20 | 2023-06-07 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3371352A (en) | 1965-01-19 | 1968-03-05 | Edwards Lab Inc | Heart valve for quick implantation having provision for ingrowth of tissue |
US3464065A (en) | 1965-07-08 | 1969-09-02 | Surgitool Inc | Prosthetic heart valve |
US3587115A (en) | 1966-05-04 | 1971-06-28 | Donald P Shiley | Prosthetic sutureless heart valves and implant tools therefor |
US3628535A (en) | 1969-11-12 | 1971-12-21 | Nibot Corp | Surgical instrument for implanting a prosthetic heart valve or the like |
US4233690A (en) * | 1978-05-19 | 1980-11-18 | Carbomedics, Inc. | Prosthetic device couplings |
US4535483A (en) * | 1983-01-17 | 1985-08-20 | Hemex, Inc. | Suture rings for heart valves |
CA1246956A (en) * | 1983-10-14 | 1988-12-20 | James Jervis | Shape memory alloys |
US4683883A (en) | 1985-04-30 | 1987-08-04 | Hemex Scientific, Inc. | Two-piece heart valve holder/rotator |
GB2181057B (en) | 1985-10-23 | 1989-09-27 | Blagoveshchensk G Med Inst | Prosthetic valve holder |
US4743253A (en) * | 1986-03-04 | 1988-05-10 | Magladry Ross E | Suture rings for heart valves and method of securing same to heart valves |
JPH0347246A (en) | 1989-04-13 | 1991-02-28 | Olympus Optical Co Ltd | Treating tool for endoscope |
US5120308A (en) | 1989-05-03 | 1992-06-09 | Progressive Angioplasty Systems, Inc. | Catheter with high tactile guide wire |
US5035709A (en) * | 1990-03-29 | 1991-07-30 | Baxter International Inc. | Mechanical heart valve with compliant sewing ring |
US5234447A (en) | 1990-08-28 | 1993-08-10 | Robert L. Kaster | Side-to-end vascular anastomotic staple apparatus |
US5397351A (en) | 1991-05-13 | 1995-03-14 | Pavcnik; Dusan | Prosthetic valve for percutaneous insertion |
CA2075241A1 (en) | 1991-10-03 | 1993-04-04 | Stephen W. Gerry | Handle for manipulating a laparoscopic tool |
US5397346A (en) * | 1992-04-28 | 1995-03-14 | Carbomedics, Inc. | Prosthetic heart valve with sewing ring |
US5236450A (en) | 1992-06-04 | 1993-08-17 | Carbon Implants, Inc. | Heart valve holder-rotator |
US5403305A (en) | 1993-04-08 | 1995-04-04 | Carbomedics, Inc. | Mitral valve prosthesis rotator |
US5531785A (en) | 1994-05-06 | 1996-07-02 | Autogenics, Inc. | Prosthetic heart valve holder |
US5443502A (en) | 1994-06-02 | 1995-08-22 | Carbomedics, Inc. | Rotatable heart valve holder |
ATE245943T1 (en) | 1994-06-17 | 2003-08-15 | Heartport Inc | SURGICAL STAPLE INSTRUMENT |
US5554185A (en) | 1994-07-18 | 1996-09-10 | Block; Peter C. | Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same |
US5582607A (en) | 1994-09-09 | 1996-12-10 | Carbomedics, Inc. | Heart valve prosthesis rotator with bendable shaft and drive mechanism |
US5609601A (en) | 1994-09-23 | 1997-03-11 | United States Surgical Corporation | Endoscopic surgical apparatus with rotation lock |
US5571175A (en) * | 1995-06-07 | 1996-11-05 | St. Jude Medical, Inc. | Suture guard for prosthetic heart valve |
US5716370A (en) | 1996-02-23 | 1998-02-10 | Williamson, Iv; Warren | Means for replacing a heart valve in a minimally invasive manner |
US5843177A (en) * | 1996-05-02 | 1998-12-01 | St. Jude Medical, Inc. | Apparatus for attaching a handle to an annuloplasty ring implantation device |
US5707380A (en) | 1996-07-23 | 1998-01-13 | United States Surgical Corporation | Anastomosis instrument and method |
US5766240A (en) * | 1996-10-28 | 1998-06-16 | Medtronic, Inc. | Rotatable suturing ring for prosthetic heart valve |
-
1998
- 1998-09-25 US US09/161,045 patent/US6200341B1/en not_active Expired - Lifetime
-
1999
- 1999-09-24 WO PCT/US1999/022255 patent/WO2000018334A1/en active Application Filing
- 1999-09-24 CA CA002345643A patent/CA2345643C/en not_active Expired - Fee Related
- 1999-09-24 DE DE69938836T patent/DE69938836D1/en not_active Expired - Lifetime
- 1999-09-24 EP EP99949874A patent/EP1115353B1/en not_active Expired - Lifetime
- 1999-09-24 JP JP2000571857A patent/JP2002525170A/en not_active Withdrawn
Non-Patent Citations (1)
Title |
---|
See references of WO0018334A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1115353B1 (en) | 2008-05-28 |
CA2345643C (en) | 2005-06-07 |
CA2345643A1 (en) | 2000-04-06 |
WO2000018334A1 (en) | 2000-04-06 |
DE69938836D1 (en) | 2008-07-10 |
US6200341B1 (en) | 2001-03-13 |
JP2002525170A (en) | 2002-08-13 |
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