EP1100966A4 - IN SITU PROCEDURE FOR GENANALYSIS - Google Patents

IN SITU PROCEDURE FOR GENANALYSIS

Info

Publication number
EP1100966A4
EP1100966A4 EP99935853A EP99935853A EP1100966A4 EP 1100966 A4 EP1100966 A4 EP 1100966A4 EP 99935853 A EP99935853 A EP 99935853A EP 99935853 A EP99935853 A EP 99935853A EP 1100966 A4 EP1100966 A4 EP 1100966A4
Authority
EP
European Patent Office
Prior art keywords
situ method
analyzing cells
analyzing
cells
situ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99935853A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1100966A1 (en
Inventor
George Mcnamara
Dirk Soenksen
Dario Cabib
Robert Buckwald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Spectral Imaging Ltd
Original Assignee
Applied Spectral Imaging Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/122,704 external-priority patent/US6007996A/en
Application filed by Applied Spectral Imaging Ltd filed Critical Applied Spectral Imaging Ltd
Publication of EP1100966A1 publication Critical patent/EP1100966A1/en
Publication of EP1100966A4 publication Critical patent/EP1100966A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/457—Correlation spectrometry, e.g. of the intensity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J2003/2866—Markers; Calibrating of scan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
EP99935853A 1998-07-27 1999-07-23 IN SITU PROCEDURE FOR GENANALYSIS Withdrawn EP1100966A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/122,704 US6007996A (en) 1995-12-12 1998-07-27 In situ method of analyzing cells
US122704 1998-07-27
PCT/US1999/016629 WO2000006774A1 (en) 1998-07-27 1999-07-23 In situ method of analyzing cells

Publications (2)

Publication Number Publication Date
EP1100966A1 EP1100966A1 (en) 2001-05-23
EP1100966A4 true EP1100966A4 (en) 2006-03-22

Family

ID=22404245

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99935853A Withdrawn EP1100966A4 (en) 1998-07-27 1999-07-23 IN SITU PROCEDURE FOR GENANALYSIS

Country Status (5)

Country Link
EP (1) EP1100966A4 (ja)
JP (1) JP2002521682A (ja)
AU (1) AU5123899A (ja)
IL (1) IL140851A0 (ja)
WO (1) WO2000006774A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7151847B2 (en) 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
US6651008B1 (en) 1999-05-14 2003-11-18 Cytokinetics, Inc. Database system including computer code for predictive cellular bioinformatics
US6743576B1 (en) 1999-05-14 2004-06-01 Cytokinetics, Inc. Database system for predictive cellular bioinformatics
US7218764B2 (en) 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US6956961B2 (en) 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
US7016787B2 (en) 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
EP1586897B1 (en) * 2002-11-07 2010-08-04 Fujitsu Limited Image analysis supporting method, image analysis supporting program, and image analysis supporting device
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
GB2423988A (en) 2003-07-18 2006-09-13 Cytokinetics Inc Characterizing biological stimuli by response curves
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
JP2005331394A (ja) 2004-05-20 2005-12-02 Olympus Corp 画像処理装置
US7323318B2 (en) 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
JP5490568B2 (ja) * 2010-02-26 2014-05-14 オリンパス株式会社 顕微鏡システム、標本観察方法およびプログラム
JP5451552B2 (ja) 2010-08-09 2014-03-26 オリンパス株式会社 顕微鏡システム、標本観察方法およびプログラム
WO2012085064A1 (en) * 2010-12-23 2012-06-28 Roche Diagnostics Gmbh Detection of a posttranslationally modified polypeptide by a bi-valent binding agent
WO2013179581A1 (ja) 2012-05-30 2013-12-05 パナソニック株式会社 画像計測装置、画像計測方法及び画像計測システム
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
EP3907497B1 (en) * 2020-05-08 2023-08-02 Leica Microsystems CMS GmbH Apparatus and method for displaying and/or printing images of a specimen including a fluorophore
EP4317946A1 (en) * 2021-06-01 2024-02-07 Huimin Zhang Use of methylene blue and fluorescein sodium double-staining in live cell imaging

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4998284A (en) * 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
WO1998013525A1 (en) * 1996-09-24 1998-04-02 Applied Spectral Imaging Ltd. Method for chromosome classification by decorrelation statistical analysis and hardware therefore

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888278A (en) * 1985-10-22 1989-12-19 University Of Massachusetts Medical Center In-situ hybridization to detect nucleic acid sequences in morphologically intact cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4998284A (en) * 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
WO1998013525A1 (en) * 1996-09-24 1998-04-02 Applied Spectral Imaging Ltd. Method for chromosome classification by decorrelation statistical analysis and hardware therefore

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ANDERSSON-ENGELS S ET AL INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING: "MULTICOLOR FLUORESCENCE IMAGING SYSTEM FOR TISSUE DIAGNOSTICS", BIOIMAGING AND TWO DIMENSIONAL SPECTROSCOPY. LOS ANGELES, JAN. 18 - 19, 1990, PROCEEDINGS OF SPIE, BELLINGHAM, SPIE, US, vol. VOL . 1205, 18 January 1990 (1990-01-18), pages 179 - 189, XP000218205 *
BALABAN R S ET AL: "Microscopic spectral imaging using a video camera", JOURNAL OF MICROSCOPY 1986 UNITED KINGDOM, vol. 141, no. 1, 1986, pages 31 - 39, XP008058927 *
LEVENSON R. M. AND FARKAS D. L.: "DIGITAL SPECTRAL IMAGING FOR HISTOPATHOLOGY AND CYTOPATHOLOGY", SPIE, vol. 2983, 1 May 1997 (1997-05-01), pages 123 - 135, XP008058932 *
MALIK Z ET AL: "FOURIER TRANSFORM MULTIPLEX SPECTROSCOPY FOR QUANTITATIVE CYTOLOGY", JOURNAL OF MICROSCOPY, OXFORD, GB, vol. 182, no. PART 2, May 1996 (1996-05-01), pages 133 - 140, XP009005240, ISSN: 0022-2720 *
MALIK ZVI ET AL: "Subcellular localization of sulfonated tetraphenyl porphines in colon carcinoma cells by spectrally resolved imaging", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 65, no. 3, 1997, pages 389 - 396, XP008058934, ISSN: 0031-8655 *
ROTHMANN C ET AL: "SPECTRAL IMAGING FOR QUANTITATIVE HISTOLOGY AND CYTOGENETICS", HISTOLOGY AND HISTOPATHOLOGY, MURCIA, ES, vol. 13, no. 3, 1 July 1998 (1998-07-01), pages 921 - 926, XP009048605, ISSN: 0213-3911 *
See also references of WO0006774A1 *
WOODBURN K W ET AL: "Localization and efficacy analysis of the phototherapeutic lutetium texaphyrin (PCI-0123) in the murine EMT6 sarcoma model", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 65, no. 3, 1997, pages 410 - 415, XP008058926, ISSN: 0031-8655 *

Also Published As

Publication number Publication date
AU5123899A (en) 2000-02-21
IL140851A0 (en) 2002-02-10
WO2000006774A1 (en) 2000-02-10
EP1100966A1 (en) 2001-05-23
JP2002521682A (ja) 2002-07-16

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