EP1100887A4 - Growth differentiation factor-11 - Google Patents

Growth differentiation factor-11

Info

Publication number
EP1100887A4
EP1100887A4 EP99938885A EP99938885A EP1100887A4 EP 1100887 A4 EP1100887 A4 EP 1100887A4 EP 99938885 A EP99938885 A EP 99938885A EP 99938885 A EP99938885 A EP 99938885A EP 1100887 A4 EP1100887 A4 EP 1100887A4
Authority
EP
European Patent Office
Prior art keywords
differentiation factor
growth differentiation
growth
factor
differentiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP99938885A
Other languages
German (de)
French (fr)
Other versions
EP1100887A1 (en
Inventor
Se-Jin Lee
Alexandra C Mcpherron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
School of Medicine of Johns Hopkins University
Original Assignee
Johns Hopkins University
School of Medicine of Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University, School of Medicine of Johns Hopkins University filed Critical Johns Hopkins University
Publication of EP1100887A1 publication Critical patent/EP1100887A1/en
Publication of EP1100887A4 publication Critical patent/EP1100887A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knockout animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/30—Bird
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
EP99938885A 1998-07-28 1999-07-28 Growth differentiation factor-11 Ceased EP1100887A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US123929 1987-11-23
US12392998A 1998-07-28 1998-07-28
PCT/US1999/017252 WO2000006716A1 (en) 1998-07-28 1999-07-28 Growth differentiation factor-11

Publications (2)

Publication Number Publication Date
EP1100887A1 EP1100887A1 (en) 2001-05-23
EP1100887A4 true EP1100887A4 (en) 2003-01-15

Family

ID=22411762

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99938885A Ceased EP1100887A4 (en) 1998-07-28 1999-07-28 Growth differentiation factor-11

Country Status (7)

Country Link
EP (1) EP1100887A4 (en)
JP (1) JP2002526034A (en)
AU (1) AU765832B2 (en)
BR (1) BR9912548A (en)
CA (1) CA2336536A1 (en)
NZ (2) NZ528341A (en)
WO (1) WO2000006716A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030167492A1 (en) 1994-07-08 2003-09-04 Johns Hopkins University School Of Medicine Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same
JP2003517580A (en) * 1999-01-21 2003-05-27 メタモーフイクス・インコーポレーテツド Growth differentiation factor inhibitors and their uses
KR100421585B1 (en) 2001-10-25 2004-03-09 한국전자통신연구원 System for cell searching of mobile station in Time Division Duplex system and method thereof
NZ747350A (en) * 2012-10-24 2020-07-31 Celgene Corp Methods for treating anemia
US20180208648A1 (en) * 2015-07-22 2018-07-26 Scholar Rock, Inc. Gdf11 binding proteins and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001845A1 (en) * 1994-07-08 1996-01-25 The Johns Hopkins University School Of Medicine Growth differentiation factor-11
US5639638A (en) * 1993-05-12 1997-06-17 Genetics Institute, Inc. DNA molecules encoding bone morpogenetic protein-11
WO1997041880A1 (en) * 1996-05-06 1997-11-13 Creative Biomolecules, Inc. Therapies for chronic renal failure

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639638A (en) * 1993-05-12 1997-06-17 Genetics Institute, Inc. DNA molecules encoding bone morpogenetic protein-11
WO1996001845A1 (en) * 1994-07-08 1996-01-25 The Johns Hopkins University School Of Medicine Growth differentiation factor-11
WO1997041880A1 (en) * 1996-05-06 1997-11-13 Creative Biomolecules, Inc. Therapies for chronic renal failure

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DUDLEY ANDREW T ET AL: "A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.", GENES & DEVELOPMENT, vol. 9, no. 22, 1995, pages 2795 - 2807, XP001107098, ISSN: 0890-9369 *
HORAN GERALD S B ET AL: "Homeotic transformation of cervical vertebrae in Hoxa-4 mutant mice.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 91, no. 26, 1994, 1994, pages 12644 - 12648, XP002203921, ISSN: 0027-8424 *
SAMPATH T K ET AL: "Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 90, no. 13, 1993, 1993, pages 6004 - 6008, XP002203920, ISSN: 0027-8424 *
See also references of WO0006716A1 *

Also Published As

Publication number Publication date
WO2000006716A1 (en) 2000-02-10
EP1100887A1 (en) 2001-05-23
NZ528341A (en) 2005-06-24
AU765832B2 (en) 2003-10-02
BR9912548A (en) 2002-01-29
CA2336536A1 (en) 2000-02-10
AU5327499A (en) 2000-02-21
JP2002526034A (en) 2002-08-20
NZ509609A (en) 2003-11-28

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