EP1095133A4 - Ftsz multimeric proteins and their uses - Google Patents

Ftsz multimeric proteins and their uses

Info

Publication number
EP1095133A4
EP1095133A4 EP99935377A EP99935377A EP1095133A4 EP 1095133 A4 EP1095133 A4 EP 1095133A4 EP 99935377 A EP99935377 A EP 99935377A EP 99935377 A EP99935377 A EP 99935377A EP 1095133 A4 EP1095133 A4 EP 1095133A4
Authority
EP
European Patent Office
Prior art keywords
ftsz
multimeric proteins
multimeric
proteins
ftsz multimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99935377A
Other languages
German (de)
French (fr)
Other versions
EP1095133A1 (en
Inventor
Curtis Preston Hensley
Kenneth H Pearce
Thomas M Sossong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1095133A1 publication Critical patent/EP1095133A1/en
Publication of EP1095133A4 publication Critical patent/EP1095133A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP99935377A 1998-07-02 1999-06-30 Ftsz multimeric proteins and their uses Withdrawn EP1095133A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9168098P 1998-07-02 1998-07-02
US91680P 1998-07-02
PCT/US1999/014890 WO2000001801A1 (en) 1998-07-02 1999-06-30 Ftsz multimeric proteins and their uses

Publications (2)

Publication Number Publication Date
EP1095133A1 EP1095133A1 (en) 2001-05-02
EP1095133A4 true EP1095133A4 (en) 2003-06-11

Family

ID=22229112

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99935377A Withdrawn EP1095133A4 (en) 1998-07-02 1999-06-30 Ftsz multimeric proteins and their uses

Country Status (3)

Country Link
EP (1) EP1095133A4 (en)
JP (1) JP2002519055A (en)
WO (1) WO2000001801A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197300B1 (en) * 1997-08-12 2001-03-06 Smithkline Beecham Corporation ftsZ
US20030017521A1 (en) * 2001-05-22 2003-01-23 President And Fellows Of Harvard College Identification of antimicrobial agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018930A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae antigens and vaccines
EP0899334A2 (en) * 1997-08-12 1999-03-03 Smithkline Beecham Corporation FtsZ polypeptides from Streptococcus pneumoniae

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US6136557A (en) * 1996-12-13 2000-10-24 Eli Lilly And Company Strepococcus pneumoniae gene sequence FtsH

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018930A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae antigens and vaccines
EP0899334A2 (en) * 1997-08-12 1999-03-03 Smithkline Beecham Corporation FtsZ polypeptides from Streptococcus pneumoniae

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] XP002213999, retrieved from EBI Database accession no. UO6462 *
MUKHERJEE A ET AL: "DYNAMIC ASSEMBLY OF FTSZ REGULATED BY GTP HYDROLYSIS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 17, no. 2, 1998, pages 462 - 464, XP000882877, ISSN: 0261-4189 *
MUKHERJEE AMIT ET AL: "Inhibition of FtsZ polymerization by SulA, an inhibitor of septation in Escherichia coli.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 6, 17 March 1998 (1998-03-17), March 17, 1998, pages 2885 - 2890, XP002234120, ISSN: 0027-8424 *
See also references of WO0001801A1 *
YU ET AL: "Inhibition of assembly of bacterial cell division protein FtsZ by the hydrophobic dye 5,5'-bis-(8-anilino-1-naphthalenesulfonate)", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 273, no. 17, 24 April 1998 (1998-04-24), pages 10216 - 10222, XP002134449, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
EP1095133A1 (en) 2001-05-02
WO2000001801A9 (en) 2000-05-25
WO2000001801A1 (en) 2000-01-13
JP2002519055A (en) 2002-07-02

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Legal Events

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