EP1089756A4 - CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS - Google Patents

CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS

Info

Publication number
EP1089756A4
EP1089756A4 EP99925696A EP99925696A EP1089756A4 EP 1089756 A4 EP1089756 A4 EP 1089756A4 EP 99925696 A EP99925696 A EP 99925696A EP 99925696 A EP99925696 A EP 99925696A EP 1089756 A4 EP1089756 A4 EP 1089756A4
Authority
EP
European Patent Office
Prior art keywords
antibody titers
ospa antibody
correlative protection
correlative
protection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99925696A
Other languages
German (de)
French (fr)
Other versions
EP1089756A1 (en
Inventor
Dennis Parenti
Yves Lobet
Marc Gillet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Biologicals SA
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Biologicals SA, SmithKline Beecham Corp filed Critical SmithKline Beecham Biologicals SA
Publication of EP1089756A1 publication Critical patent/EP1089756A1/en
Publication of EP1089756A4 publication Critical patent/EP1089756A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP99925696A 1998-05-22 1999-05-20 CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS Withdrawn EP1089756A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8645698P 1998-05-22 1998-05-22
US86456P 1998-05-22
US12741599P 1999-04-01 1999-04-01
US127415P 1999-04-01
PCT/US1999/011158 WO1999061048A1 (en) 1998-05-22 1999-05-20 CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS

Publications (2)

Publication Number Publication Date
EP1089756A1 EP1089756A1 (en) 2001-04-11
EP1089756A4 true EP1089756A4 (en) 2002-07-17

Family

ID=26774772

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99925696A Withdrawn EP1089756A4 (en) 1998-05-22 1999-05-20 CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS

Country Status (4)

Country Link
EP (1) EP1089756A4 (en)
AU (1) AU4193399A (en)
CA (1) CA2332979A1 (en)
WO (1) WO1999061048A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013049039A1 (en) * 2011-09-30 2013-04-04 Advanced Laboratory Services, Inc. Compositions and methods for culturing spirochetes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0812593A1 (en) * 1993-03-23 1997-12-17 SMITHKLINE BEECHAM BIOLOGICALS s.a. Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0812593A1 (en) * 1993-03-23 1997-12-17 SMITHKLINE BEECHAM BIOLOGICALS s.a. Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KELLER DAVID ET AL: "Safety and immunogenicity of a recombinant outer surface protein A Lyme vaccine.", JAMA (JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION), vol. 271, no. 22, 1994, pages 1764 - 1768, XP001070476, ISSN: 0098-7484 *
See also references of WO9961048A1 *
VAN HOECKE C ET AL: "Alternative vaccination schedules (0, 1, and 6 months versus 0, 1, and 12 months) for a recombinant OspA Lyme disease vaccine.", CLINICAL INFECTIOUS DISEASES, vol. 28, no. 6, June 1999 (1999-06-01), pages 1260 - 1264, XP002197376, ISSN: 1058-4838 *
VAN HOECKE C ET AL: "Clinical and immunological assessment of a candidate Lyme disease vaccine in healthy adults: antibody persistence and effect of a booster dose at month 12", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 16, no. 17, 1 October 1998 (1998-10-01), pages 1688 - 1692, XP004139711, ISSN: 0264-410X *
VAN HOECKE C ET AL: "Evaluation of a lipoprotein OspA vaccine administered following a 0, 1, 2 month primary vaccination course with a booster at month 12.", ABSTRACTS OF THE INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND, vol. 35, 1995, 35th Interscience Conference on Antimicrobial Agents and Chemotherapy;San Francisco, California, USA; September 17-20, 1995, 1995, pages 172, XP001069749 *

Also Published As

Publication number Publication date
WO1999061048A1 (en) 1999-12-02
AU4193399A (en) 1999-12-13
EP1089756A1 (en) 2001-04-11
CA2332979A1 (en) 1999-12-02

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Legal Events

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