EP1078099A4 - Identification de ligands peptidiques de proteines cibles par la technique des banques complementaires de cibles tclt - Google Patents

Identification de ligands peptidiques de proteines cibles par la technique des banques complementaires de cibles tclt

Info

Publication number
EP1078099A4
EP1078099A4 EP99917315A EP99917315A EP1078099A4 EP 1078099 A4 EP1078099 A4 EP 1078099A4 EP 99917315 A EP99917315 A EP 99917315A EP 99917315 A EP99917315 A EP 99917315A EP 1078099 A4 EP1078099 A4 EP 1078099A4
Authority
EP
European Patent Office
Prior art keywords
target
tclt
peptide ligands
library technology
identifying peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99917315A
Other languages
German (de)
English (en)
Other versions
EP1078099A1 (fr
Inventor
Fang Fang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1078099A1 publication Critical patent/EP1078099A1/fr
Publication of EP1078099A4 publication Critical patent/EP1078099A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP99917315A 1998-04-24 1999-04-19 Identification de ligands peptidiques de proteines cibles par la technique des banques complementaires de cibles tclt Withdrawn EP1078099A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8304698P 1998-04-24 1998-04-24
US83046P 1998-04-24
PCT/US1999/006537 WO1999055911A1 (fr) 1998-04-24 1999-04-19 Identification de ligands peptidiques de proteines cibles par la technique des banques complementaires de cibles tclt

Publications (2)

Publication Number Publication Date
EP1078099A1 EP1078099A1 (fr) 2001-02-28
EP1078099A4 true EP1078099A4 (fr) 2005-02-09

Family

ID=22175835

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99917315A Withdrawn EP1078099A4 (fr) 1998-04-24 1999-04-19 Identification de ligands peptidiques de proteines cibles par la technique des banques complementaires de cibles tclt

Country Status (4)

Country Link
EP (1) EP1078099A4 (fr)
AU (1) AU762711C (fr)
CA (1) CA2350163A1 (fr)
WO (1) WO1999055911A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9908533D0 (en) 1999-04-14 1999-06-09 Novartis Ag Organic compounds
GB2356401A (en) * 1999-11-19 2001-05-23 Proteom Ltd Method for manipulating protein or DNA sequence data
GB9929469D0 (en) * 1999-12-13 2000-02-09 Proteom Ltd Complementary peptide ligands generated from plant genomes
GB9929466D0 (en) * 1999-12-13 2000-02-09 Proteom Ltd Complementary peptide ligands generated from microbial genome sequences
GB9929464D0 (en) * 1999-12-13 2000-02-09 Proteom Ltd Complementary peptide ligande generated from the human genome
GB0025251D0 (en) * 2000-10-14 2000-11-29 Proteom Ltd Antisense peptides to Fc receptors and their uses
EP2604283A1 (fr) * 2007-02-16 2013-06-19 KTB Tumorforschungsgesellschaft mbH Récepteur et promédicament ciblé antigène

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077195A (en) * 1985-03-01 1991-12-31 Board Of Reagents, The University Of Texas System Polypeptides complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known and methods of design therefor
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5081584A (en) * 1989-03-13 1992-01-14 United States Of America Computer-assisted design of anti-peptides based on the amino acid sequence of a target peptide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HOLSWORTH DANIEL D ET AL: "Antisense-designed peptides: A comparative study focusing on possible complements to angiotensin II", PEPTIDE RESEARCH, vol. 7, no. 4, 1994, pages 185 - 193, XP008034402, ISSN: 1040-5704 *
KAMTEKAR S ET AL: "Protein design by binary patterning of polar and nonpolar amino acids", SCIENCE; SCIENCE DEC 10 1993, vol. 262, no. 5140, 10 December 1993 (1993-12-10), pages 1680 - 1685, XP001182910 *
PESTOV D G ET AL: "Genetic selection of growth-inhibitory sequences in mammalian cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, no. 26, 20 December 1994 (1994-12-20), pages 12549 - 12553, XP002188815, ISSN: 0027-8424 *
See also references of WO9955911A1 *

Also Published As

Publication number Publication date
AU762711C (en) 2004-05-27
CA2350163A1 (fr) 1999-11-04
WO1999055911A1 (fr) 1999-11-04
AU762711B2 (en) 2003-07-03
EP1078099A1 (fr) 2001-02-28
AU3546599A (en) 1999-11-16

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