EP1078040A4 - Nouveaux recepteurs couples a la proteine-g (nt2lp), presentant une homologie pour les recepteurs de la neurotensine-2 - Google Patents

Nouveaux recepteurs couples a la proteine-g (nt2lp), presentant une homologie pour les recepteurs de la neurotensine-2

Info

Publication number
EP1078040A4
EP1078040A4 EP99921872A EP99921872A EP1078040A4 EP 1078040 A4 EP1078040 A4 EP 1078040A4 EP 99921872 A EP99921872 A EP 99921872A EP 99921872 A EP99921872 A EP 99921872A EP 1078040 A4 EP1078040 A4 EP 1078040A4
Authority
EP
European Patent Office
Prior art keywords
receptors
nt2lp
neurotensin
homology
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99921872A
Other languages
German (de)
English (en)
Other versions
EP1078040A1 (fr
Inventor
Rory Curtis
Maria Alexandra Glucksmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of EP1078040A1 publication Critical patent/EP1078040A1/fr
Publication of EP1078040A4 publication Critical patent/EP1078040A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP99921872A 1998-05-11 1999-05-11 Nouveaux recepteurs couples a la proteine-g (nt2lp), presentant une homologie pour les recepteurs de la neurotensine-2 Withdrawn EP1078040A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7631398A 1998-05-11 1998-05-11
US76313 1998-05-11
US22349298A 1998-12-30 1998-12-30
US223492 1998-12-30
PCT/US1999/010311 WO1999058641A2 (fr) 1998-05-11 1999-05-11 Nouveaux recepteurs couples a la proteine-g (nt2lp), presentant une homologie pour les recepteurs de la neurotensine-2

Publications (2)

Publication Number Publication Date
EP1078040A1 EP1078040A1 (fr) 2001-02-28
EP1078040A4 true EP1078040A4 (fr) 2003-01-02

Family

ID=26757952

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99921872A Withdrawn EP1078040A4 (fr) 1998-05-11 1999-05-11 Nouveaux recepteurs couples a la proteine-g (nt2lp), presentant une homologie pour les recepteurs de la neurotensine-2

Country Status (5)

Country Link
EP (1) EP1078040A4 (fr)
JP (1) JP2003525576A (fr)
AU (1) AU3897699A (fr)
CA (1) CA2327548A1 (fr)
WO (1) WO1999058641A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4551401A (en) * 2000-03-08 2001-09-17 Upjohn Co Novel g protein-coupled receptors
AU2001263346A1 (en) * 2000-05-22 2001-12-03 Pharmacia And Upjohn Company G protein-coupled receptors

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHALON P ET AL: "MOLECULAR CLONING OF A LEVOCABASTINE-SENSITIVE NEUROTENSIN BINDING SITE", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 386, no. 2/3, 20 May 1996 (1996-05-20), pages 91 - 94, XP002048142, ISSN: 0014-5793 *
DATABASE SWISSPROT [online] XP002213848, Database accession no. Q63384 *
DATABASE SWISSPROT [online] XP002213849, Database accession no. p70310 *
DATABASE SWISSPROT [online] XP002213850, retrieved from Q95665 *
MAZELLA J ET AL: "STRUCTURE, FUNCTIONAL EXPRESSION, AND CEREBRAL LOCALIZATION OF THE LEVOCABASTINE-SENSITIVE NEUROTENSIN/NEUROMEDIN N RECEPTOR FROM MOUSE BRAIN", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 16, no. 18, 15 September 1996 (1996-09-15), pages 5613 - 5620, XP002048143, ISSN: 0270-6474 *
VITA N ET AL: "NEUROTENSIN IS AN ANTAGONIST OF THE HUMAN NEUROTENSIN NT2 RECEPTOR EXPRESSED IN CHINESE HAMSTER OVARY CELLS", EUROPEAN JOURNAL OF PHARMACOLOGY, AMSTERDAM, NL, vol. 360, 1998, pages 265 - 272, XP000879367, ISSN: 0014-2999 *

Also Published As

Publication number Publication date
WO1999058641A2 (fr) 1999-11-18
JP2003525576A (ja) 2003-09-02
AU3897699A (en) 1999-11-29
WO1999058641A8 (fr) 2000-01-20
CA2327548A1 (fr) 1999-11-18
EP1078040A1 (fr) 2001-02-28

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