EP1073897A4 - Lifetime-based sensing of sodium and potassium - Google Patents

Lifetime-based sensing of sodium and potassium

Info

Publication number
EP1073897A4
EP1073897A4 EP99912686A EP99912686A EP1073897A4 EP 1073897 A4 EP1073897 A4 EP 1073897A4 EP 99912686 A EP99912686 A EP 99912686A EP 99912686 A EP99912686 A EP 99912686A EP 1073897 A4 EP1073897 A4 EP 1073897A4
Authority
EP
European Patent Office
Prior art keywords
lifetime
potassium
sodium
based sensing
sensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99912686A
Other languages
German (de)
French (fr)
Other versions
EP1073897A1 (en
Inventor
Joseph R Lakowicz
Henryk Szmacinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland at Baltimore
Original Assignee
University of Maryland at Baltimore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland at Baltimore filed Critical University of Maryland at Baltimore
Publication of EP1073897A1 publication Critical patent/EP1073897A1/en
Publication of EP1073897A4 publication Critical patent/EP1073897A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
EP99912686A 1998-03-20 1999-03-19 Lifetime-based sensing of sodium and potassium Withdrawn EP1073897A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7885698P 1998-03-20 1998-03-20
US78856P 1998-03-20
US11155498P 1998-12-09 1998-12-09
US111554P 1998-12-09
PCT/US1999/005980 WO1999047918A1 (en) 1998-03-20 1999-03-19 Lifetime-based sensing of sodium and potassium

Publications (2)

Publication Number Publication Date
EP1073897A1 EP1073897A1 (en) 2001-02-07
EP1073897A4 true EP1073897A4 (en) 2006-10-25

Family

ID=26761024

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99912686A Withdrawn EP1073897A4 (en) 1998-03-20 1999-03-19 Lifetime-based sensing of sodium and potassium

Country Status (3)

Country Link
EP (1) EP1073897A4 (en)
CA (1) CA2325140A1 (en)
WO (1) WO1999047918A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020725A1 (en) * 2001-08-31 2003-03-13 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Coumarin compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759767A (en) * 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5134232A (en) * 1988-11-14 1992-07-28 The Regents Of The University Of California Fluorescent indicator dyes for alkali metal cations
EP0694164A1 (en) * 1991-05-03 1996-01-31 Joseph R. Lakowicz Method for optically measuring chemical analytes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759767A (en) * 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HENRYK SZYMANSKI, JOSEPH R. LAKOWICZ: "Sodium Green as a potential probe for intracellular sodium imaging based on fluorescence lifetime", ANALYTICAL BIOCHEMISTRY, vol. 250, 1 August 1997 (1997-08-01), pages 131 - 138, XP002383498 *
See also references of WO9947918A1 *
SZMACINSKI H ET AL: "LIFETIME-BASED SENSING", TOPICS IN FLUORESCENCE SPECTROSCOPY, vol. 4, 1994, pages 295 - 334, XP002912416 *

Also Published As

Publication number Publication date
EP1073897A1 (en) 2001-02-07
CA2325140A1 (en) 1999-09-23
WO1999047918A1 (en) 1999-09-23

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Legal Events

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Ipc: G01N 21/64 20060101ALI20070731BHEP

Ipc: G01N 33/52 20060101AFI20070731BHEP

RTI1 Title (correction)

Free format text: LUMINESCENT LIFETIME-BASED MEASUREMENT OF SODIUM CONCENTRATION

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Effective date: 20080115