EP1064539A1 - Heated electrochemical cell - Google Patents
Heated electrochemical cellInfo
- Publication number
- EP1064539A1 EP1064539A1 EP99910001A EP99910001A EP1064539A1 EP 1064539 A1 EP1064539 A1 EP 1064539A1 EP 99910001 A EP99910001 A EP 99910001A EP 99910001 A EP99910001 A EP 99910001A EP 1064539 A1 EP1064539 A1 EP 1064539A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- sample
- analyte
- concentration
- cell
- electrochemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Definitions
- This invention relates to a method and apparatus for measuring the concentration
- concentration of glucose in blood is not limited to that use and has general
- a blood sample is combined with an
- GDH glucose dehydrogenase
- An oxidising mediator for example ferricyanide is
- ferrocyanide in the process.
- concentration of ferrocyanide produced is the concentration of ferrocyanide produced.
- a preferred method for accurately determining the concentration of an analyte is to
- the invention consists in a method for determining the
- concentration of an analyte in a sample comprising the steps of:
- reaction profile as used herein
- reaction profile illustrates the change of concentration of a species with respect to time. Such a profile can provide a skilled addressee with both qualitative and quantitative
- the predetermined point on the reaction profile is a steady state
- the species representative of the concentration of the analyte is a mediator, for instance
- the sample is heated electrically, for
- the invention consists in an electrochemical cell
- Figure 1 shows schematically a sensor strip according to the invention in a cross-
- FIG. 2 shows the results of tests conducted in accordance with one embodiment
- FIG. 3 shows the results of tests conducted in accordance with another
- glucose concentration is
- present invention differs in that the sample is heated.
- a reagent that liberates heat on contact with blood is
- ferrocyanide concentration is temperature independent an accurate assessment of glucose
- the heat generating reagent can be added after the sample is
- sample temperature is raised by from 5 to 15°C, for example from
- the temperature peak is
- the sample may then be electrically heated by passing
- an electrochemical sensor comprising a plastic substrate 1 bearing a first
- first electrode 2 The opposite face of cylindrical cell 10 is covered by a second electrode
- electrode layer 4 (for example a sputter coating of palladium) which in this case is
- a metal foil layer 6 provides electrical contact to a
- resistive bridge 9 formed in the rubber or plastic layer 5.
- plastic provides insulation against heat loss through the metal foil.
- aperture 8 in layer 7 provides for electrical contact with metal foil layer 6. Resistive
- bridge 9 is formed for example from carbon particles impregnated into the rubber or
- Resistive heating elements may be
- an electrically insulating layer which can be made partially conductive in particular
- the potential across the resistive element can be maintained during
- the means for applying the potential to the resistive in another embodiment, the means for applying the potential to the resistive
- the power level required can be
- the voltage signal is alternating any reaction that occurs during one half voltage cycle is
- heater element was fabricated by sputtering two parallel low resistance metallic tracks
- the parallel low resistance tracks protruded from the end of the strip and provided
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP2388A AUPP238898A0 (en) | 1998-03-12 | 1998-03-12 | Heated electrochemical cell |
AUPP238898 | 1998-03-12 | ||
PCT/AU1999/000152 WO1999046585A1 (en) | 1998-03-12 | 1999-03-11 | Heated electrochemical cell |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1064539A1 true EP1064539A1 (en) | 2001-01-03 |
EP1064539A4 EP1064539A4 (en) | 2006-08-02 |
Family
ID=3806651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99910001A Withdrawn EP1064539A4 (en) | 1998-03-12 | 1999-03-11 | Heated electrochemical cell |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1064539A4 (en) |
JP (1) | JP2002506969A (en) |
AU (1) | AUPP238898A0 (en) |
CA (1) | CA2322757A1 (en) |
TW (1) | TWI240071B (en) |
WO (1) | WO1999046585A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6413410B1 (en) | 1996-06-19 | 2002-07-02 | Lifescan, Inc. | Electrochemical cell |
AUPN661995A0 (en) | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
US6780296B1 (en) * | 1999-12-23 | 2004-08-24 | Roche Diagnostics Corporation | Thermally conductive sensor |
US6716577B1 (en) | 2000-02-02 | 2004-04-06 | Lifescan, Inc. | Electrochemical test strip for use in analyte determination |
AU2007209797B2 (en) * | 2000-07-14 | 2010-06-03 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
EP1303758B1 (en) * | 2000-07-14 | 2006-12-27 | LifeScan, Inc. | Electrochemical method for measuring chemical reaction rates |
CA2733852A1 (en) * | 2000-07-14 | 2002-01-24 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
AU2006203606B2 (en) * | 2000-07-14 | 2007-05-17 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
US6444115B1 (en) | 2000-07-14 | 2002-09-03 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
GB0130684D0 (en) * | 2001-12-21 | 2002-02-06 | Oxford Biosensors Ltd | Micro-band electrode |
US20060134713A1 (en) | 2002-03-21 | 2006-06-22 | Lifescan, Inc. | Biosensor apparatus and methods of use |
EP1467206A1 (en) * | 2003-04-08 | 2004-10-13 | Roche Diagnostics GmbH | Biosensor system |
MX2007004331A (en) | 2004-10-12 | 2007-06-05 | Bayer Healthcare Llc | Concentration determination in a diffusion barrier layer. |
EP1882745A1 (en) * | 2006-07-25 | 2008-01-30 | The Swatch Group Research and Development Ltd. | Electrochemical system for dosing of a biological compound by an enzyme |
CN108896540B (en) * | 2018-05-02 | 2021-08-24 | 武汉职业技术学院 | Aquatic product formaldehyde detection card |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3084877B2 (en) * | 1992-01-21 | 2000-09-04 | 松下電器産業株式会社 | Manufacturing method of glucose sensor |
US5607565A (en) * | 1995-03-27 | 1997-03-04 | Coulter Corporation | Apparatus for measuring analytes in a fluid sample |
AUPN661995A0 (en) * | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
-
1998
- 1998-03-12 AU AUPP2388A patent/AUPP238898A0/en not_active Abandoned
-
1999
- 1999-03-11 CA CA002322757A patent/CA2322757A1/en not_active Abandoned
- 1999-03-11 JP JP2000535917A patent/JP2002506969A/en not_active Withdrawn
- 1999-03-11 TW TW088103765A patent/TWI240071B/en active
- 1999-03-11 WO PCT/AU1999/000152 patent/WO1999046585A1/en not_active Application Discontinuation
- 1999-03-11 EP EP99910001A patent/EP1064539A4/en not_active Withdrawn
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO9946585A1 * |
Also Published As
Publication number | Publication date |
---|---|
AUPP238898A0 (en) | 1998-04-09 |
WO1999046585A1 (en) | 1999-09-16 |
CA2322757A1 (en) | 1999-09-16 |
JP2002506969A (en) | 2002-03-05 |
TWI240071B (en) | 2005-09-21 |
EP1064539A4 (en) | 2006-08-02 |
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Legal Events
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