EP1058737A4 - Novel fdrg protein and nucleic acid molecules and uses therefor - Google Patents

Novel fdrg protein and nucleic acid molecules and uses therefor

Info

Publication number
EP1058737A4
EP1058737A4 EP99912241A EP99912241A EP1058737A4 EP 1058737 A4 EP1058737 A4 EP 1058737A4 EP 99912241 A EP99912241 A EP 99912241A EP 99912241 A EP99912241 A EP 99912241A EP 1058737 A4 EP1058737 A4 EP 1058737A4
Authority
EP
European Patent Office
Prior art keywords
fdrg
protein
novel
nucleic acid
acid molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99912241A
Other languages
German (de)
French (fr)
Other versions
EP1058737A1 (en
Inventor
Douglas A Holtzman
Bruce M Spiegelman
Clifford Hyunsuk Yoon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Millennium Pharmaceuticals Inc
Original Assignee
Dana Farber Cancer Institute Inc
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc, Millennium Pharmaceuticals Inc filed Critical Dana Farber Cancer Institute Inc
Publication of EP1058737A1 publication Critical patent/EP1058737A1/en
Publication of EP1058737A4 publication Critical patent/EP1058737A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP99912241A 1998-03-02 1999-03-02 Novel fdrg protein and nucleic acid molecules and uses therefor Withdrawn EP1058737A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3353998A 1998-03-02 1998-03-02
US33539 1998-03-02
PCT/US1999/004548 WO1999045135A1 (en) 1998-03-02 1999-03-02 Novel fdrg protein and nucleic acid molecules and uses therefor

Publications (2)

Publication Number Publication Date
EP1058737A1 EP1058737A1 (en) 2000-12-13
EP1058737A4 true EP1058737A4 (en) 2003-01-02

Family

ID=21870993

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99912241A Withdrawn EP1058737A4 (en) 1998-03-02 1999-03-02 Novel fdrg protein and nucleic acid molecules and uses therefor

Country Status (6)

Country Link
EP (1) EP1058737A4 (en)
JP (1) JP2002516067A (en)
AU (1) AU3065799A (en)
CA (1) CA2322425A1 (en)
IL (1) IL138216A0 (en)
WO (1) WO1999045135A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1607402T3 (en) * 1999-03-08 2007-04-16 Genentech Inc Tumor Treatment Compositions and Methods
AU2001249929A1 (en) * 2000-04-07 2001-10-23 Dana-Farber Cancer Institute Inc. Fdrg proteins and nucleic acid molecules and uses therefor
CA2408745A1 (en) * 2000-05-13 2001-11-22 Bioacta Ltd Anti-angiogenic polypeptides
US6869766B2 (en) 2000-12-22 2005-03-22 The Regents Of The University Of California Gene associated with regulation of adiposity and insulin response
US20050123925A1 (en) 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
CN1930305A (en) * 2004-01-14 2007-03-14 詹森药业有限公司 Methods of using peroxisome proliferator-activated receptor alpha target genes
EP1586902A3 (en) * 2004-03-30 2006-02-15 F.Hoffmann-La Roche Ag ANGPTL4/FIAF as marker for PPARdelta modulation
CN102641503A (en) 2004-07-20 2012-08-22 健泰科生物技术公司 Inhibitors of angiopoietin-like 4 protein, combinations, and their use
CN101080419B (en) 2004-07-20 2014-07-02 健泰科生物技术公司 Compositions and methods of using angiopoietin-like 4 protein
US8604185B2 (en) 2004-07-20 2013-12-10 Genentech, Inc. Inhibitors of angiopoietin-like 4 protein, combinations, and their use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996011269A2 (en) * 1994-10-07 1996-04-18 Regeneron Pharmaceuticals, Inc. Tie-2 ligands, methods of making and uses thereof
WO1999015654A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie receptor tyrosine kinase ligand homologues
WO1999032515A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Angiopoietin homolog, dna encoding it, and method of making it

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996011269A2 (en) * 1994-10-07 1996-04-18 Regeneron Pharmaceuticals, Inc. Tie-2 ligands, methods of making and uses thereof
WO1999015654A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie receptor tyrosine kinase ligand homologues
WO1999032515A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Angiopoietin homolog, dna encoding it, and method of making it

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 29 February 1996 (1996-02-29), HILLIER L. ET AL.: "yw93f11.r1 Soares_placenta_8to9weeks_2NbHP8to9W Homo sapiens cDNA clone.", XP002217323, retrieved from EBI Database accession no. N57259 *
KERSTEN SANDER ET AL: "Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 37, 15 September 2000 (2000-09-15), pages 28488 - 28493, XP002217322, ISSN: 0021-9258 *
KIM I ET AL: "HEPATIC EXPRESSION, SYNTHESIS AND SECRETION OF A NOVEL FIBRINOGEN/ANGIOPOIETIN-RELATED PROTEIN THAT PREVENTS ENDOTHELIAL-CELL APOPTOSIS", BIOCHEMICAL JOURNAL, THE BIOCHEMICAL SOCIETY, LONDON, GB, vol. 346, no. 3, 15 March 2000 (2000-03-15), pages 603 - 610, XP000971125, ISSN: 0264-6021 *
See also references of WO9945135A1 *

Also Published As

Publication number Publication date
JP2002516067A (en) 2002-06-04
CA2322425A1 (en) 1999-09-10
IL138216A0 (en) 2001-10-31
WO1999045135A1 (en) 1999-09-10
AU3065799A (en) 1999-09-20
EP1058737A1 (en) 2000-12-13

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