EP1053472A4 - Energy transfer dyes - Google Patents
Energy transfer dyesInfo
- Publication number
- EP1053472A4 EP1053472A4 EP99905590A EP99905590A EP1053472A4 EP 1053472 A4 EP1053472 A4 EP 1053472A4 EP 99905590 A EP99905590 A EP 99905590A EP 99905590 A EP99905590 A EP 99905590A EP 1053472 A4 EP1053472 A4 EP 1053472A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- dye
- energy transfer
- group
- succinimidyl ester
- carboxypentyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/88—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18111 | 1993-02-17 | ||
US1811198A | 1998-02-03 | 1998-02-03 | |
PCT/US1999/002105 WO1999039203A1 (en) | 1998-02-03 | 1999-02-02 | Energy transfer dyes |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1053472A1 EP1053472A1 (en) | 2000-11-22 |
EP1053472A4 true EP1053472A4 (en) | 2002-04-03 |
Family
ID=21786306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99905590A Withdrawn EP1053472A4 (en) | 1998-02-03 | 1999-02-02 | Energy transfer dyes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1053472A4 (en) |
JP (1) | JP2002502034A (en) |
AU (1) | AU2571899A (en) |
CA (1) | CA2319490A1 (en) |
WO (1) | WO1999039203A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001204497A (en) * | 2000-01-20 | 2001-07-31 | Japan Science & Technology Corp | Method for detecting dna by dna hybridization method by utilizing transfer of fluorescence resonance energy |
GB0024351D0 (en) * | 2000-10-04 | 2000-11-22 | Amersham Pharm Biotech Uk Ltd | Dye-labelled peptide and method |
US8097412B2 (en) | 2008-07-12 | 2012-01-17 | Biodiagnostics, Inc. | DNA-based test for detection of annual and intermediate ryegrass |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0805190A2 (en) * | 1996-05-03 | 1997-11-05 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5654419A (en) * | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
US5728528A (en) * | 1995-09-20 | 1998-03-17 | The Regents Of The University Of California | Universal spacer/energy transfer dyes |
US5853992A (en) * | 1996-10-04 | 1998-12-29 | The Regents Of The University Of California | Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels |
US5804386A (en) * | 1997-01-15 | 1998-09-08 | Incyte Pharmaceuticals, Inc. | Sets of labeled energy transfer fluorescent primers and their use in multi component analysis |
-
1999
- 1999-02-02 JP JP2000529606A patent/JP2002502034A/en active Pending
- 1999-02-02 AU AU25718/99A patent/AU2571899A/en not_active Abandoned
- 1999-02-02 CA CA002319490A patent/CA2319490A1/en not_active Abandoned
- 1999-02-02 EP EP99905590A patent/EP1053472A4/en not_active Withdrawn
- 1999-02-02 WO PCT/US1999/002105 patent/WO1999039203A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0805190A2 (en) * | 1996-05-03 | 1997-11-05 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
Non-Patent Citations (3)
Title |
---|
J. B. RANDOLPH, A. S. WAGGONER: "Stability, specifity and fluorescence brightness of multiply-labeled fluorescent DNA probes", NUCLEIC ACIDS RESEARCH, vol. 25, no. 14, 1997, pages 2923 - 2929, XP002074426 * |
See also references of WO9939203A1 * |
Z. ZHU ET AL.: "Directly labeled DNA probes using fluorescent nucleotides with different length linkers", NUCLEIC ACIDS RESEARCH, vol. 22, no. 16, 1994, pages 3418 - 3422, XP002074425 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999039203A1 (en) | 1999-08-05 |
CA2319490A1 (en) | 1999-08-05 |
AU2571899A (en) | 1999-08-16 |
JP2002502034A (en) | 2002-01-22 |
EP1053472A1 (en) | 2000-11-22 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20000724 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FLICK, PARKE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020215 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7G 01N 33/533 A, 7C 09B 62/44 B, 7G 01N 33/52 B, 7G 01N 33/545 B, 7G 01N 33/548 B, 7G 01N 33/552 B, 7G 01N 33/554 B |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: GE HEALTHCARE BIO-SCIENCES CORP. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060818 |