EP1032586A4 - Hypusine peptides - Google Patents

Hypusine peptides

Info

Publication number
EP1032586A4
EP1032586A4 EP98943259A EP98943259A EP1032586A4 EP 1032586 A4 EP1032586 A4 EP 1032586A4 EP 98943259 A EP98943259 A EP 98943259A EP 98943259 A EP98943259 A EP 98943259A EP 1032586 A4 EP1032586 A4 EP 1032586A4
Authority
EP
European Patent Office
Prior art keywords
hypusine
peptides
hypusine peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98943259A
Other languages
German (de)
French (fr)
Other versions
EP1032586A1 (en
Inventor
Raymond J Bergeron Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida
University of Florida Research Foundation Inc
Original Assignee
University of Florida
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Florida, University of Florida Research Foundation Inc filed Critical University of Florida
Publication of EP1032586A1 publication Critical patent/EP1032586A1/en
Publication of EP1032586A4 publication Critical patent/EP1032586A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
EP98943259A 1997-11-21 1998-08-19 Hypusine peptides Withdrawn EP1032586A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97565697A 1997-11-21 1997-11-21
US975656 1997-11-21
PCT/US1998/017221 WO1999026963A1 (en) 1997-11-21 1998-08-19 Hypusine peptides

Publications (2)

Publication Number Publication Date
EP1032586A1 EP1032586A1 (en) 2000-09-06
EP1032586A4 true EP1032586A4 (en) 2000-11-15

Family

ID=25523257

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98943259A Withdrawn EP1032586A4 (en) 1997-11-21 1998-08-19 Hypusine peptides

Country Status (5)

Country Link
EP (1) EP1032586A4 (en)
JP (1) JP2001524488A (en)
AU (1) AU9109098A (en)
CA (1) CA2310027A1 (en)
WO (1) WO1999026963A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010131962A2 (en) * 2009-05-15 2010-11-18 Stichting Het Nederlands Kanker Instituut Lysine compounds and their use in site- and chemoselective modification of peptides and proteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344846A (en) * 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
US6017693A (en) * 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
R.J.BERGERON ET AL.: "Developement of a Hypusine Reagent for Peptide Synthesis", J.ORG.CHEM., vol. 62, no. 10, May 1997 (1997-05-01), pages 3285 - 90, XP002914567 *
See also references of WO9926963A1 *

Also Published As

Publication number Publication date
JP2001524488A (en) 2001-12-04
WO1999026963A1 (en) 1999-06-03
CA2310027A1 (en) 1999-06-03
EP1032586A1 (en) 2000-09-06
AU9109098A (en) 1999-06-15

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