EP1030592A4 - Systeme d'imagerie non invasif pour ecoulement sanguin turbulent - Google Patents
Systeme d'imagerie non invasif pour ecoulement sanguin turbulentInfo
- Publication number
- EP1030592A4 EP1030592A4 EP97947373A EP97947373A EP1030592A4 EP 1030592 A4 EP1030592 A4 EP 1030592A4 EP 97947373 A EP97947373 A EP 97947373A EP 97947373 A EP97947373 A EP 97947373A EP 1030592 A4 EP1030592 A4 EP 1030592A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- patient
- sensors
- blood flow
- sounds
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8979—Combined Doppler and pulse-echo imaging systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B7/00—Instruments for auscultation
- A61B7/02—Stethoscopes
- A61B7/04—Electric stethoscopes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52023—Details of receivers
- G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4405—Device being mounted on a trolley
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/02—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems using reflection of acoustic waves
- G01S15/50—Systems of measurement, based on relative movement of the target
- G01S15/52—Discriminating between fixed and moving objects or between objects moving at different speeds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/899—Combination of imaging systems with ancillary equipment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8993—Three dimensional imaging systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/5205—Means for monitoring or calibrating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52053—Display arrangements
- G01S7/52057—Cathode ray tube displays
- G01S7/52073—Production of cursor lines, markers or indicia by electronic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52077—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging with means for elimination of unwanted signals, e.g. noise or interference
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52079—Constructional features
Definitions
- the present invention relates generally to non-
- occluded vessel may produce sounds which are
- turbulent blood flow are known. See, e.g., Lees, et al . ,
- This invention provides reliable, non-invasive
- the shear wave component is
- isolated shear wave component is processed to provide a
- uniform display may indicate the presence of an occlusion
- the invention may include sensor signal conditioning
- the signal processing circuitry may be any circuitry
- the invention may include means for enhancement of the
- field refers to a volume of space
- the wave front is
- the source in relation to the array can be determined.
- the location would have 3 dimensions either in Cartesian,
- phase shifts between the sensors may be different.
- the direction would have two angular dimensions in
- the algorithm is typically called a delay and sum beamformer.
- Steering Vector vector derived from a path model
- Vessel Any part of the human circulatory system
- Abnormal Blood Flow Any non-laminar, e.g.,
- the array of sensors may be fixed
- Phonocardiographv The graphic representation of the
- phonocardiography also comprises
- the vessels carrying blood toward the heart include the aorta and pulmonary artery.
- the vessels carrying blood toward the heart include the
- Algorithm A series of steps or a method to achieve
- an information objective e.g., the identification or
- Compression Wave wave which compresses the medium
- Shear Wave A wave whose propagated disturbance is a
- Beamformer n algorithm that defines or creates a beam.
- Beamformin The process of selectively controlling
- Beamforming is a search through 3-D
- null In the context of this invention, null means
- Null space is a vector subspace, if present, of a matrix.
- the goal may be to place the null at the
- the interfering signal e.g., a jammer
- Velocity Filtering eans for separating wave forms
- shear waves from compression waves as a
- Figures 26A, B and C and Figure 27 illustrate of a three
- the four dimension is wave speed.
- Photogrammetry nalytic photogrammetry refers to
- photogrammetry refers to the computer processing of
- Extraction includes the steps of
- Figure 1 is a front and side view of one form of a
- Figure 2A is a view of a second form of a clinical
- Figure 2B is a view of the Figure 2A form of the
- Figure 3 is a schematic that depicts one form of a
- Figure 4 illustrates a portion of the top surface of
- Figure 5 depicts a five element preselected sensor
- Figure 6 illustrates a prior art nine sensor array
- Sensors 1-5 are positioned in an outer circle, sensors 6-
- Figure 7 is a schematic block diagram that depicts
- Figure 8 is schematic block diagram that depicts an
- Figure 9 is a schematic block diagram that depicts
- FIGS. 10 and 11 are circuit diagrams for the
- Figure 12 is a plot of the beam steering angle 0 to
- Figure 13 is a plot of the beam steering angle 0
- Figure 14 is a plot of the beam steering angle 0
- GN gain 1, 10,100, 1000 and 10,000.
- Figure 15 is a plot comparing the beam steering
- beamformer as a function of output from 0 to 1 from five
- Figure 16 illustrates a frequency number
- Figure 17 illustrates a frequency number
- Figure 18 illustrates a windowed 2-D transform
- Figure 19 is a stacked plot that depicts synthetic
- Figure 20 is a stacked plot that depicts synthetic
- Figure 21 is a plot of the beam steering angle 0
- First, second, third and fourth nulls at 0.1, 0.3, 0.7
- Figure 22 is similar to Figure 21 except that a
- Figure 23 is a plot of the beam steering angle 0 to
- Figure 24 is similar to Figure 23 except that a null
- Figure 25 is similar to Figure 24, except that it
- Figure 26A is an x-y background projection of a
- Figure 26B is an x-z depth projection of a regularly
- Figure 26C is a y-z depth projection of a regularly
- Figure 27 displays the 3D grid points in three
- Figure 28A is an x-y projection of a 4D optimally
- Figure 28B is an x-z depth projection of a 4D
- Figure 28C is a y-z depth projection of a 4D
- Figure 29 is a 3D projection of the 4D grid onto
- Figure 30 is the flow diagram or algorithm that
- Figure 31 is a flow diagram that illustrates further
- Figure 32 is a flow diagram that illustrates the
- Figure 33 shows spectrograms ambient room noise
- Figure 34 is a volumetric image of a computer
- Figure 35 is a volumetric image of data obtained
- severities levels of stenosis, i.e., 25%, 50%, 62%,
- Figures 36A and 36B compare a volumetric acoustic
- Figures 37A and 37B are volumetric images of a
- Figure 38 depicts a comparison of acoustic features
- Figure 40 is a flow chart that illustrates
- Figure 41 is a flow chart or logic diagram that
- Figure 42 is a flow chart which illustrates the
- Figure 40 illustrates operations of one embodiment
- Such relative locations may be determined
- acoustic sensors may be any form of sensor suitable for
- obtaining acoustic information but are preferably
- This acoustic information preferably
- ECG ECG
- the acquired information regarding the sensors the
- parsing of the data preferably includes isolating sensor data corresponding to the time period for the second
- the sensor data could be
- the averaged data is then beamformed (block 2008)
- Figure 41 illustrates the averaging process
- difference matrix may be determined as described above.
- matrices are averaged (block 2028) . This averaging
- phase difference matrices are then decomposed into their
- This optimal grid provides search through
- the grid is
- the optimal grid may be
- the 4D grid is then used to beamform through the
- a new region or regions of interest may be
- This new region of interest is preferably
- the region of interest is the region of interest
- gain grid may be precomputed or computed for each use.
- the adjustable gain grid is also preferably
- instructions may be provided to a processor to produce a
- processor create means for implementing the functions
- program instructions may be executed by a processor to
- Figure 1 illustrates a preferred clinical
- workstation configuration 110 which may include a
- the rotating push dial 114 as shown, has no
- switches 113 as shown, is a two-state (ON-OFF) device.
- the data may be
- operating system is a 32 -bit Microsoft NT workstation
- Figures 2A and 2B are schematics that show a form of
- Element 117 is
- the element 119 has arms 120 foldable into
- the acoustic imaging system processes signals
- the sensors measure body surface response to
- S/N signal to noise ratio
- signal may also be included to provide a reference for
- the sensors may be charge or voltage mode
- Preferred individual sensors comprise a stretched
- piezoelectric film transducer typically, the transducer
- dimension width is less than one-half wavelength for the
- Figure 5 illustrates a device 130 in which five
- sensors 131 (one of five sensors) are fixed in a
- the array includes a centrally positioned
- the device 130 is operatively
- FIG. 6 comprises eight equally spaced sensors
- a ninth sensor is at the center of the
- the sensors may be any suitable type of sensors.
- the sensors may be any suitable type of sensors.
- the sensors may be any suitable type of sensors.
- acoustic imaging system may amplify the signals from the
- the MUX box may include a
- interface may be an analog interface circuit suitable for
- ECG sensor interface is provided as a channel input to
- the multiplexer such that when selected, the ECG sensor
- output may be converted by the analog to digital converter from an analog signal to a digital signal.
- a breath gating circuit which may be
- the control logic may include circuitry for (i) gain
- a filter which may be
- multiple pole high pass filter such as a Butterworth or
- the output of the filter is any suitable filter.
- the output of the filter is any suitable filter.
- the output of the analog to digital converter is buffered and provided to a digital I/O board resident
- This sub-system may provide 16-bit A/D readings to the
- the workstation of Figure 8 also includes an analog
- the ECG sensors the ECG sensors and the respiration sensor.
- analog sub-system may process this information in analog
- the analog sub-system shown in Figure 8 includes a
- digital I/O board may be a PC-DIO-24 board available from
- the power sub-system illustrated in Figure 8 may be any power sub-system illustrated in Figure 8.
- Input devices such as a keyboard, rotary dial and soft
- switches may also be provided for receiving input from a
- a removable media file or other storage device may be any removable media file or other storage device.
- the Figure 8 power sub-system may be industry
- the computer including the CRT display and
- keyboard preferably is an industry standard, e.g., IBM
- the sensors may be connected to the
- analog sub-system which may output digital data
- analog sub-system may be incorporated
- FIGS. 10 and 11 are circuit diagrams for the
- FIG. 10 depicts one of the 32 analog channels that
- FIG 11 are the seven digital input "data request"
- A/D Converter of ADC analog-to-digital converter
- Figure 11 are digital buffers for output to the PC.
- the system may execute a self-test each time it is
- User controls may include a
- the user access may be limited to
- the patient may be a patient having ECG leads, and verifying the signals.
- the patient may be a patient having ECG leads, and verifying the signals.
- the patient may be a patient having ECG leads, and verifying the signals.
- the patient may be a patient having ECG leads, and verifying the signals.
- the patient may be a patient having ECG leads, and verifying the signals.
- the patient may be a patient having ECG leads, and verifying the signals.
- the system may record
- the instrument may provide feedback to guide the
- Preferred embodiments may provide real-time
- the instrument may store acquired data over a
- the data stored may contain a record which can be mapped
- the instrument preferably
- the system includes means to internally retain patient records.
- the system may include means to internally retain patient records.
- the system may include means to internally retain patient records.
- the system may include means to internally retain patient records.
- the system may include means to internally retain patient records.
- the system may include means to internally retain patient records.
- workstation may apply a fast executing (less than three
- the workstation may execute
- a copy of the patient's record may be
- system may indicate if the storage medium is full and also warn the operator of an attempt to delete a record
- the workstation may provide the
- Equation 1 This matrix is shown by Equation 1:
- Equation 2 Equation 2
- IPM in Equation 2 becomes a function of both
- IPM is a
- the receiver signals are first ensembled to
- the R matrix may be
- interchannel phase difference matrices may be produced.
- Equation 7 R matrices is given by Equation 7:
- path model information is contained in steering vectors.
- Equation 8 shows this different
- the beamformer output can be computed.
- Equation 9
- Figures 12 and 13 are plots of a normalized
- gain/resolution null space beamformer to acquire and process abnormal blood flow noise and image turbulent
- blood flow may include:
- the uniformly spaced three dimensional grid is
- This space has dimensions in X, Y and Z of
- each of the sensors may be determined using stereo
- CCD charge coupled device
- the cameras are rigidly mounted 18
- Retro-reflective tape is affixed to the sensor tops
- LEDs mounted around each camera's lens.
- infrared filter is mounted in front of the camera lens.
- the filter allows the reflected IR light to pass through
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Radar, Positioning & Navigation (AREA)
- Acoustics & Sound (AREA)
- Remote Sensing (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07009147A EP1808122A3 (fr) | 1997-11-10 | 1997-11-10 | Système d'imagerie de flux sanguin turbulent non invasif |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1997/020186 WO1999023940A1 (fr) | 1997-11-10 | 1997-11-10 | Systeme d'imagerie non invasif pour ecoulement sanguin turbulent |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07009147A Division EP1808122A3 (fr) | 1997-11-10 | 1997-11-10 | Système d'imagerie de flux sanguin turbulent non invasif |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1030592A1 EP1030592A1 (fr) | 2000-08-30 |
EP1030592A4 true EP1030592A4 (fr) | 2004-04-07 |
Family
ID=22262012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97947373A Withdrawn EP1030592A4 (fr) | 1997-11-10 | 1997-11-10 | Systeme d'imagerie non invasif pour ecoulement sanguin turbulent |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1030592A4 (fr) |
AU (1) | AU5247198A (fr) |
WO (1) | WO1999023940A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000027287A1 (fr) | 1998-11-09 | 2000-05-18 | Medacoustics, Inc. | Detection acoustique non invasive de coronaropathie |
CN105246399B (zh) * | 2013-06-26 | 2017-10-03 | 英特尔公司 | 前导中风风险指标的检测 |
WO2015144811A1 (fr) * | 2014-03-26 | 2015-10-01 | Koninklijke Philips N.V. | Système de rhéologie et système de rhéologie rm avec commande de rétroaction de capteur de rhéologie |
WO2016207092A1 (fr) * | 2015-06-26 | 2016-12-29 | Koninklijke Philips N.V. | Système et procédé de production d'une image ultrasonore |
US20200315574A1 (en) * | 2016-06-24 | 2020-10-08 | Canon Kabushiki Kaisha | Apparatus and information processing method |
CN107505232B (zh) | 2017-07-21 | 2019-09-03 | 无锡海斯凯尔医学技术有限公司 | 运动信息获取方法及装置 |
US11045163B2 (en) | 2017-09-19 | 2021-06-29 | Ausculsciences, Inc. | Method of detecting noise in auscultatory sound signals of a coronary-artery-disease detection system |
CA3075930A1 (fr) | 2017-09-19 | 2019-03-28 | Ausculsciences, Inc. | Systeme et procede de detection du decouplage d'un capteur sonore d'auscultation d'un sujet de test |
US10925573B2 (en) | 2017-10-04 | 2021-02-23 | Ausculsciences, Inc. | Auscultatory sound-or-vibration sensor |
US20190117165A1 (en) | 2017-10-20 | 2019-04-25 | Jikang ZENG | Coronary artery disease detection signal processing system and method |
US11284827B2 (en) | 2017-10-21 | 2022-03-29 | Ausculsciences, Inc. | Medical decision support system |
Citations (2)
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US5327893A (en) * | 1992-10-19 | 1994-07-12 | Rensselaer Polytechnic Institute | Detection of cholesterol deposits in arteries |
US5365937A (en) * | 1992-09-09 | 1994-11-22 | Mcg International, Inc. | Disposable sensing device with contaneous conformance |
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US4586514A (en) * | 1983-08-10 | 1986-05-06 | Biotronics Instruments | Phonoangiographic spectral analysing apparatus |
US5109863A (en) * | 1989-10-26 | 1992-05-05 | Rutgers, The State University Of New Jersey | Noninvasive diagnostic system for coronary artery disease |
US5638823A (en) * | 1995-08-28 | 1997-06-17 | Rutgers University | System and method for noninvasive detection of arterial stenosis |
-
1997
- 1997-11-10 EP EP97947373A patent/EP1030592A4/fr not_active Withdrawn
- 1997-11-10 AU AU52471/98A patent/AU5247198A/en not_active Abandoned
- 1997-11-10 WO PCT/US1997/020186 patent/WO1999023940A1/fr not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5365937A (en) * | 1992-09-09 | 1994-11-22 | Mcg International, Inc. | Disposable sensing device with contaneous conformance |
US5327893A (en) * | 1992-10-19 | 1994-07-12 | Rensselaer Polytechnic Institute | Detection of cholesterol deposits in arteries |
Non-Patent Citations (4)
Title |
---|
FRANKLIN D ET AL: "Quantitative ultrasonic interferometry applicable to differential transit time flow measurement: preliminary report", ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, 1995., IEEE 17TH ANNUAL CONFERENCE MONTREAL, QUE., CANADA 20-23 SEPT. 1995, NEW YORK, NY, USA,IEEE, US, 20 September 1995 (1995-09-20), pages 619 - 620, XP010215538, ISBN: 0-7803-2475-7 * |
PIETRABISSA R ET AL: "A lumped parameter model to evaluate the fluid dynamics of different coronary bypasses", MEDICAL ENGINEERING & PHYSICS, SEPT. 1996, ELSEVIER, UK, vol. 18, no. 6, September 1996 (1996-09-01), pages 477 - 484, XP001161212, ISSN: 1350-4533 * |
See also references of WO9923940A1 * |
SEMMLOW J L ET AL: "Non-invasive diagnosis of coronary artery disease by enhanced coronary phonocardiography", IEEE 1982 FRONTIERS OF ENGINEERING IN HEALTH CARE. PROCEEDINGS - FOURTH ANNUAL CONFERENCE, PHILADELPHIA, PA, USA, 20-21 SEPT. 1982, 1982, New York, NY, USA, IEEE, USA, pages 181 - 185, XP008015143 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999023940A1 (fr) | 1999-05-20 |
AU5247198A (en) | 1999-05-31 |
EP1030592A1 (fr) | 2000-08-30 |
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