EP1030592A4 - Systeme d'imagerie non invasif pour ecoulement sanguin turbulent - Google Patents

Systeme d'imagerie non invasif pour ecoulement sanguin turbulent

Info

Publication number
EP1030592A4
EP1030592A4 EP97947373A EP97947373A EP1030592A4 EP 1030592 A4 EP1030592 A4 EP 1030592A4 EP 97947373 A EP97947373 A EP 97947373A EP 97947373 A EP97947373 A EP 97947373A EP 1030592 A4 EP1030592 A4 EP 1030592A4
Authority
EP
European Patent Office
Prior art keywords
patient
sensors
blood flow
sounds
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97947373A
Other languages
German (de)
English (en)
Other versions
EP1030592A1 (fr
Inventor
Charles E Chassaing
Scott Donaldson Stearns
Mark Harold Vanhorn
Carl Ashley Ryden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harris Corp
Original Assignee
MedAcoustics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MedAcoustics Inc filed Critical MedAcoustics Inc
Priority to EP07009147A priority Critical patent/EP1808122A3/fr
Publication of EP1030592A1 publication Critical patent/EP1030592A1/fr
Publication of EP1030592A4 publication Critical patent/EP1030592A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8979—Combined Doppler and pulse-echo imaging systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B7/00—Instruments for auscultation
    • A61B7/02—Stethoscopes
    • A61B7/04—Electric stethoscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023—Details of receivers
    • G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4405—Device being mounted on a trolley
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/02—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems using reflection of acoustic waves
    • G01S15/50—Systems of measurement, based on relative movement of the target
    • G01S15/52—Discriminating between fixed and moving objects or between objects moving at different speeds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/899—Combination of imaging systems with ancillary equipment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8993—Three dimensional imaging systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/5205—Means for monitoring or calibrating
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52053—Display arrangements
    • G01S7/52057—Cathode ray tube displays
    • G01S7/52073—Production of cursor lines, markers or indicia by electronic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52077—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging with means for elimination of unwanted signals, e.g. noise or interference
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52079—Constructional features

Definitions

  • the present invention relates generally to non-
  • occluded vessel may produce sounds which are
  • turbulent blood flow are known. See, e.g., Lees, et al . ,
  • This invention provides reliable, non-invasive
  • the shear wave component is
  • isolated shear wave component is processed to provide a
  • uniform display may indicate the presence of an occlusion
  • the invention may include sensor signal conditioning
  • the signal processing circuitry may be any circuitry
  • the invention may include means for enhancement of the
  • field refers to a volume of space
  • the wave front is
  • the source in relation to the array can be determined.
  • the location would have 3 dimensions either in Cartesian,
  • phase shifts between the sensors may be different.
  • the direction would have two angular dimensions in
  • the algorithm is typically called a delay and sum beamformer.
  • Steering Vector vector derived from a path model
  • Vessel Any part of the human circulatory system
  • Abnormal Blood Flow Any non-laminar, e.g.,
  • the array of sensors may be fixed
  • Phonocardiographv The graphic representation of the
  • phonocardiography also comprises
  • the vessels carrying blood toward the heart include the aorta and pulmonary artery.
  • the vessels carrying blood toward the heart include the
  • Algorithm A series of steps or a method to achieve
  • an information objective e.g., the identification or
  • Compression Wave wave which compresses the medium
  • Shear Wave A wave whose propagated disturbance is a
  • Beamformer n algorithm that defines or creates a beam.
  • Beamformin The process of selectively controlling
  • Beamforming is a search through 3-D
  • null In the context of this invention, null means
  • Null space is a vector subspace, if present, of a matrix.
  • the goal may be to place the null at the
  • the interfering signal e.g., a jammer
  • Velocity Filtering eans for separating wave forms
  • shear waves from compression waves as a
  • Figures 26A, B and C and Figure 27 illustrate of a three
  • the four dimension is wave speed.
  • Photogrammetry nalytic photogrammetry refers to
  • photogrammetry refers to the computer processing of
  • Extraction includes the steps of
  • Figure 1 is a front and side view of one form of a
  • Figure 2A is a view of a second form of a clinical
  • Figure 2B is a view of the Figure 2A form of the
  • Figure 3 is a schematic that depicts one form of a
  • Figure 4 illustrates a portion of the top surface of
  • Figure 5 depicts a five element preselected sensor
  • Figure 6 illustrates a prior art nine sensor array
  • Sensors 1-5 are positioned in an outer circle, sensors 6-
  • Figure 7 is a schematic block diagram that depicts
  • Figure 8 is schematic block diagram that depicts an
  • Figure 9 is a schematic block diagram that depicts
  • FIGS. 10 and 11 are circuit diagrams for the
  • Figure 12 is a plot of the beam steering angle 0 to
  • Figure 13 is a plot of the beam steering angle 0
  • Figure 14 is a plot of the beam steering angle 0
  • GN gain 1, 10,100, 1000 and 10,000.
  • Figure 15 is a plot comparing the beam steering
  • beamformer as a function of output from 0 to 1 from five
  • Figure 16 illustrates a frequency number
  • Figure 17 illustrates a frequency number
  • Figure 18 illustrates a windowed 2-D transform
  • Figure 19 is a stacked plot that depicts synthetic
  • Figure 20 is a stacked plot that depicts synthetic
  • Figure 21 is a plot of the beam steering angle 0
  • First, second, third and fourth nulls at 0.1, 0.3, 0.7
  • Figure 22 is similar to Figure 21 except that a
  • Figure 23 is a plot of the beam steering angle 0 to
  • Figure 24 is similar to Figure 23 except that a null
  • Figure 25 is similar to Figure 24, except that it
  • Figure 26A is an x-y background projection of a
  • Figure 26B is an x-z depth projection of a regularly
  • Figure 26C is a y-z depth projection of a regularly
  • Figure 27 displays the 3D grid points in three
  • Figure 28A is an x-y projection of a 4D optimally
  • Figure 28B is an x-z depth projection of a 4D
  • Figure 28C is a y-z depth projection of a 4D
  • Figure 29 is a 3D projection of the 4D grid onto
  • Figure 30 is the flow diagram or algorithm that
  • Figure 31 is a flow diagram that illustrates further
  • Figure 32 is a flow diagram that illustrates the
  • Figure 33 shows spectrograms ambient room noise
  • Figure 34 is a volumetric image of a computer
  • Figure 35 is a volumetric image of data obtained
  • severities levels of stenosis, i.e., 25%, 50%, 62%,
  • Figures 36A and 36B compare a volumetric acoustic
  • Figures 37A and 37B are volumetric images of a
  • Figure 38 depicts a comparison of acoustic features
  • Figure 40 is a flow chart that illustrates
  • Figure 41 is a flow chart or logic diagram that
  • Figure 42 is a flow chart which illustrates the
  • Figure 40 illustrates operations of one embodiment
  • Such relative locations may be determined
  • acoustic sensors may be any form of sensor suitable for
  • obtaining acoustic information but are preferably
  • This acoustic information preferably
  • ECG ECG
  • the acquired information regarding the sensors the
  • parsing of the data preferably includes isolating sensor data corresponding to the time period for the second
  • the sensor data could be
  • the averaged data is then beamformed (block 2008)
  • Figure 41 illustrates the averaging process
  • difference matrix may be determined as described above.
  • matrices are averaged (block 2028) . This averaging
  • phase difference matrices are then decomposed into their
  • This optimal grid provides search through
  • the grid is
  • the optimal grid may be
  • the 4D grid is then used to beamform through the
  • a new region or regions of interest may be
  • This new region of interest is preferably
  • the region of interest is the region of interest
  • gain grid may be precomputed or computed for each use.
  • the adjustable gain grid is also preferably
  • instructions may be provided to a processor to produce a
  • processor create means for implementing the functions
  • program instructions may be executed by a processor to
  • Figure 1 illustrates a preferred clinical
  • workstation configuration 110 which may include a
  • the rotating push dial 114 as shown, has no
  • switches 113 as shown, is a two-state (ON-OFF) device.
  • the data may be
  • operating system is a 32 -bit Microsoft NT workstation
  • Figures 2A and 2B are schematics that show a form of
  • Element 117 is
  • the element 119 has arms 120 foldable into
  • the acoustic imaging system processes signals
  • the sensors measure body surface response to
  • S/N signal to noise ratio
  • signal may also be included to provide a reference for
  • the sensors may be charge or voltage mode
  • Preferred individual sensors comprise a stretched
  • piezoelectric film transducer typically, the transducer
  • dimension width is less than one-half wavelength for the
  • Figure 5 illustrates a device 130 in which five
  • sensors 131 (one of five sensors) are fixed in a
  • the array includes a centrally positioned
  • the device 130 is operatively
  • FIG. 6 comprises eight equally spaced sensors
  • a ninth sensor is at the center of the
  • the sensors may be any suitable type of sensors.
  • the sensors may be any suitable type of sensors.
  • the sensors may be any suitable type of sensors.
  • acoustic imaging system may amplify the signals from the
  • the MUX box may include a
  • interface may be an analog interface circuit suitable for
  • ECG sensor interface is provided as a channel input to
  • the multiplexer such that when selected, the ECG sensor
  • output may be converted by the analog to digital converter from an analog signal to a digital signal.
  • a breath gating circuit which may be
  • the control logic may include circuitry for (i) gain
  • a filter which may be
  • multiple pole high pass filter such as a Butterworth or
  • the output of the filter is any suitable filter.
  • the output of the filter is any suitable filter.
  • the output of the analog to digital converter is buffered and provided to a digital I/O board resident
  • This sub-system may provide 16-bit A/D readings to the
  • the workstation of Figure 8 also includes an analog
  • the ECG sensors the ECG sensors and the respiration sensor.
  • analog sub-system may process this information in analog
  • the analog sub-system shown in Figure 8 includes a
  • digital I/O board may be a PC-DIO-24 board available from
  • the power sub-system illustrated in Figure 8 may be any power sub-system illustrated in Figure 8.
  • Input devices such as a keyboard, rotary dial and soft
  • switches may also be provided for receiving input from a
  • a removable media file or other storage device may be any removable media file or other storage device.
  • the Figure 8 power sub-system may be industry
  • the computer including the CRT display and
  • keyboard preferably is an industry standard, e.g., IBM
  • the sensors may be connected to the
  • analog sub-system which may output digital data
  • analog sub-system may be incorporated
  • FIGS. 10 and 11 are circuit diagrams for the
  • FIG. 10 depicts one of the 32 analog channels that
  • FIG 11 are the seven digital input "data request"
  • A/D Converter of ADC analog-to-digital converter
  • Figure 11 are digital buffers for output to the PC.
  • the system may execute a self-test each time it is
  • User controls may include a
  • the user access may be limited to
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the patient may be a patient having ECG leads, and verifying the signals.
  • the system may record
  • the instrument may provide feedback to guide the
  • Preferred embodiments may provide real-time
  • the instrument may store acquired data over a
  • the data stored may contain a record which can be mapped
  • the instrument preferably
  • the system includes means to internally retain patient records.
  • the system may include means to internally retain patient records.
  • the system may include means to internally retain patient records.
  • the system may include means to internally retain patient records.
  • the system may include means to internally retain patient records.
  • the system may include means to internally retain patient records.
  • workstation may apply a fast executing (less than three
  • the workstation may execute
  • a copy of the patient's record may be
  • system may indicate if the storage medium is full and also warn the operator of an attempt to delete a record
  • the workstation may provide the
  • Equation 1 This matrix is shown by Equation 1:
  • Equation 2 Equation 2
  • IPM in Equation 2 becomes a function of both
  • IPM is a
  • the receiver signals are first ensembled to
  • the R matrix may be
  • interchannel phase difference matrices may be produced.
  • Equation 7 R matrices is given by Equation 7:
  • path model information is contained in steering vectors.
  • Equation 8 shows this different
  • the beamformer output can be computed.
  • Equation 9
  • Figures 12 and 13 are plots of a normalized
  • gain/resolution null space beamformer to acquire and process abnormal blood flow noise and image turbulent
  • blood flow may include:
  • the uniformly spaced three dimensional grid is
  • This space has dimensions in X, Y and Z of
  • each of the sensors may be determined using stereo
  • CCD charge coupled device
  • the cameras are rigidly mounted 18
  • Retro-reflective tape is affixed to the sensor tops
  • LEDs mounted around each camera's lens.
  • infrared filter is mounted in front of the camera lens.
  • the filter allows the reflected IR light to pass through

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Remote Sensing (AREA)
  • Acoustics & Sound (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

Cette invention concerne un procédé et un instrument non invasifs de détection et de localisation de débit sanguin anormal dans un vaisseau. Un ensemble aligné de capteurs (131) est disposé sur une zone du corps du patient située au-dessus d'un volume dans lequel le débit sanguin semble anormal. Les signaux détectés par cet ensemble de capteurs (131) sont traités et affichés sous forme d'une image qui indique la présence ou non d'un débit sanguin anormal.
EP97947373A 1997-11-10 1997-11-10 Systeme d'imagerie non invasif pour ecoulement sanguin turbulent Withdrawn EP1030592A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07009147A EP1808122A3 (fr) 1997-11-10 1997-11-10 Système d'imagerie de flux sanguin turbulent non invasif

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1997/020186 WO1999023940A1 (fr) 1997-11-10 1997-11-10 Systeme d'imagerie non invasif pour ecoulement sanguin turbulent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP07009147A Division EP1808122A3 (fr) 1997-11-10 1997-11-10 Système d'imagerie de flux sanguin turbulent non invasif

Publications (2)

Publication Number Publication Date
EP1030592A1 EP1030592A1 (fr) 2000-08-30
EP1030592A4 true EP1030592A4 (fr) 2004-04-07

Family

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Family Applications (1)

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Country Status (3)

Country Link
EP (1) EP1030592A4 (fr)
AU (1) AU5247198A (fr)
WO (1) WO1999023940A1 (fr)

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AU2344200A (en) 1998-11-09 2000-05-29 Medacoustics, Inc. Non-invasive acoustic detection of coronary artery disease
WO2014209303A1 (fr) * 2013-06-26 2014-12-31 Intel Corporation Détection d'indicateur prépondérant de risque d'accident vasculaire cérébral
US10918304B2 (en) * 2014-03-26 2021-02-16 Koninklijke Philips N.V. Rheology system and MR rheology system with rheology sensor feedback control
WO2016207092A1 (fr) * 2015-06-26 2016-12-29 Koninklijke Philips N.V. Système et procédé de production d'une image ultrasonore
US20200315574A1 (en) * 2016-06-24 2020-10-08 Canon Kabushiki Kaisha Apparatus and information processing method
CN107505232B (zh) 2017-07-21 2019-09-03 无锡海斯凯尔医学技术有限公司 运动信息获取方法及装置
US11045163B2 (en) 2017-09-19 2021-06-29 Ausculsciences, Inc. Method of detecting noise in auscultatory sound signals of a coronary-artery-disease detection system
WO2019060455A1 (fr) 2017-09-19 2019-03-28 Ausculsciences, Inc. Système et procédé de détection du découplage d'un capteur sonore d'auscultation d'un sujet de test
WO2019071050A2 (fr) 2017-10-04 2019-04-11 Ausculsciences, Inc. Capteur de sons ou de vibrations d'auscultation
US11045144B2 (en) 2017-10-20 2021-06-29 Ausculsciences, Inc. Coronary artery disease detection signal processing system and method
US11284827B2 (en) 2017-10-21 2022-03-29 Ausculsciences, Inc. Medical decision support system

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