EP1030557A4 - Proteinproduktion durch expression in sekretorische drüsen - Google Patents

Proteinproduktion durch expression in sekretorische drüsen

Info

Publication number
EP1030557A4
EP1030557A4 EP98950707A EP98950707A EP1030557A4 EP 1030557 A4 EP1030557 A4 EP 1030557A4 EP 98950707 A EP98950707 A EP 98950707A EP 98950707 A EP98950707 A EP 98950707A EP 1030557 A4 EP1030557 A4 EP 1030557A4
Authority
EP
European Patent Office
Prior art keywords
protein delivery
secretory gland
gland expression
expression
secretory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98950707A
Other languages
English (en)
French (fr)
Other versions
EP1030557A1 (de
Inventor
Stephen S Rothman
Ira D Goldfine
Michael S German
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/942,939 external-priority patent/US6004944A/en
Application filed by University of California filed Critical University of California
Publication of EP1030557A1 publication Critical patent/EP1030557A1/de
Publication of EP1030557A4 publication Critical patent/EP1030557A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP98950707A 1997-10-02 1998-09-24 Proteinproduktion durch expression in sekretorische drüsen Withdrawn EP1030557A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US942939 1997-10-02
US08/942,939 US6004944A (en) 1995-03-24 1997-10-02 Protein delivery by secretory gland expression
PCT/US1998/020199 WO1999017610A1 (en) 1997-10-02 1998-09-24 Protein delivery by secretory gland expression

Publications (2)

Publication Number Publication Date
EP1030557A1 EP1030557A1 (de) 2000-08-30
EP1030557A4 true EP1030557A4 (de) 2002-07-31

Family

ID=25478850

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98950707A Withdrawn EP1030557A4 (de) 1997-10-02 1998-09-24 Proteinproduktion durch expression in sekretorische drüsen

Country Status (5)

Country Link
EP (1) EP1030557A4 (de)
JP (1) JP2001518316A (de)
AU (1) AU744279B2 (de)
CA (1) CA2304803A1 (de)
WO (1) WO1999017610A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531455B1 (en) 1995-03-24 2003-03-11 The Regents Of The University Of California Delivery of polynucleotides by secretory gland expression
US7115795B1 (en) 1999-04-23 2006-10-03 University Of Guelph Transgenic animals expressing salivary proteins
CN100379860C (zh) * 1999-04-23 2008-04-09 圭尔夫大学 表达唾液蛋白的转基因动物
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
JP6989262B2 (ja) 2014-10-27 2022-01-05 アセコー インコーポレイテッド 皮下外来患者管理
WO2017031440A1 (en) 2015-08-20 2017-02-23 Aseko, Inc. Diabetes management therapy advisor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030050A1 (en) * 1995-03-24 1996-10-03 The Regents Of The University Of California Gene therapy by secretory gland expression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030050A1 (en) * 1995-03-24 1996-10-03 The Regents Of The University Of California Gene therapy by secretory gland expression

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
AMERICAN JOURNAL OF PHYSIOLOGY, vol. 241, no. 2, 1981, pages G171 - G175, ISSN: 0002-9513 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1981, MIYASAKA K ET AL: "ENDOCRINE SECRETION OF ALPHA AMYLASE BY THE PANCREAS", XP002197457, Database accession no. PREV198273016961 *
GOLDFINE IRA D ET AL: "The endocrine secretion of human insulin and growth hormone by exocrine gland of the gastrointestinal tract.", NATURE BIOTECHNOLOGY, vol. 15, no. 13, December 1997 (1997-12-01), pages 1378 - 1382, XP002197456, ISSN: 1087-0156 *
KAGAMI H ET AL: "EVIDENCE FOR THE SYSTEMIC DELIVERY OF A TRANSGENE PRODUCT FROM SALIVARY GLANDS", HUMAN GENE THERAPY, XX, XX, vol. 7, 10 November 1996 (1996-11-10), pages 2177 - 2184, XP002915661, ISSN: 1043-0342 *
See also references of WO9917610A1 *
SOSA-PINEDA B ET AL: "THE PAX4 GENE IS ESSENTIAL FOR DIFFERENTIATION OF INSULIN-PRODUCING BETA CELLS IN THE MAMMALIAN PANCREAS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 386, 27 March 1997 (1997-03-27), pages 399 - 402, XP002067725, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
AU744279B2 (en) 2002-02-21
WO1999017610A1 (en) 1999-04-15
JP2001518316A (ja) 2001-10-16
AU9668998A (en) 1999-04-27
CA2304803A1 (en) 1999-04-15
EP1030557A1 (de) 2000-08-30

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