EP1007035A4 - Polythiophene anti-tumor agents - Google Patents
Polythiophene anti-tumor agentsInfo
- Publication number
- EP1007035A4 EP1007035A4 EP96945379A EP96945379A EP1007035A4 EP 1007035 A4 EP1007035 A4 EP 1007035A4 EP 96945379 A EP96945379 A EP 96945379A EP 96945379 A EP96945379 A EP 96945379A EP 1007035 A4 EP1007035 A4 EP 1007035A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- polythiophene
- tumor agents
- tumor
- agents
- polythiophene anti
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1996/019118 WO1998023269A1 (en) | 1996-11-26 | 1996-11-26 | Polythiophene anti-tumor agents |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1007035A1 EP1007035A1 (en) | 2000-06-14 |
EP1007035A4 true EP1007035A4 (en) | 2000-11-22 |
Family
ID=22256220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96945379A Withdrawn EP1007035A4 (en) | 1996-11-26 | 1996-11-26 | Polythiophene anti-tumor agents |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1007035A4 (en) |
JP (1) | JP2001506624A (en) |
AU (1) | AU1564797A (en) |
CA (1) | CA2272275A1 (en) |
WO (1) | WO1998023269A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1831205A4 (en) * | 2004-09-14 | 2010-12-01 | Univ Northwestern | Carbonyl-functionalized thiophene compounds and related device structures |
EP2350042B1 (en) | 2008-10-17 | 2015-07-29 | Cpl Bcx Pharma Ab | Novel thiophene compounds for use in theraphy |
CN113603674B (en) * | 2021-07-23 | 2022-10-14 | 上海应用技术大学 | 5,5 '-substituted 3,3' -bithiophene derivative, synthesis method and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4937256A (en) * | 1988-06-01 | 1990-06-26 | Basf Aktiengesellschaft | Thiophene compounds |
US5508440A (en) * | 1993-06-04 | 1996-04-16 | Industrial Technology Research Institute | Hydroxymethylpolythiophene derivatives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3050442A (en) * | 1957-05-31 | 1962-08-21 | Philips Corp | Method of destroying nematodes with polythienyl compounds |
US5045563A (en) * | 1986-08-26 | 1991-09-03 | Her Majesty The Queen In Right Of Canada, As Represented By Minister Of National Defence Of Her Majesty's Canadian Government | Phototoxic compounds for use as insect control agents |
US4861692A (en) * | 1986-12-22 | 1989-08-29 | Fuji Electric Company, Ltd. | Electrophotographic photosensitive material containing thiophene compound |
DK0454204T3 (en) * | 1990-04-27 | 1995-08-28 | Duphar Int Res | Process for Photochemical Isomerization of Organic Compounds and Influence on a Photosensitizer |
US5578636A (en) * | 1994-04-08 | 1996-11-26 | Purdue Research Foundation | Polythiophene anti-tumor agents |
-
1996
- 1996-11-26 CA CA002272275A patent/CA2272275A1/en not_active Abandoned
- 1996-11-26 EP EP96945379A patent/EP1007035A4/en not_active Withdrawn
- 1996-11-26 WO PCT/US1996/019118 patent/WO1998023269A1/en not_active Application Discontinuation
- 1996-11-26 JP JP52659098A patent/JP2001506624A/en active Pending
- 1996-11-26 AU AU15647/97A patent/AU1564797A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4937256A (en) * | 1988-06-01 | 1990-06-26 | Basf Aktiengesellschaft | Thiophene compounds |
US5508440A (en) * | 1993-06-04 | 1996-04-16 | Industrial Technology Research Institute | Hydroxymethylpolythiophene derivatives |
Non-Patent Citations (4)
Title |
---|
ASHENDEL C L_(A): "Structure-activity relationship of alpha-terthiophene series for inhibition of protein kinase C and cytotoxicity.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING, no. 2604, March 1995 (1995-03-01), XP002147664 * |
ASHENDEL C L_(A): "Terthiophenes as novel inhibitors of protein kinase C.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING, no. 2661, March 1994 (1994-03-01), XP002147662 * |
See also references of WO9823269A1 * |
WATERS D J_(A) T_(A): "In vivo antitumor efficacy of a novel polythiophene against ras-transformed human bronchial epithelial cells.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING, no. 2705, March 1996 (1996-03-01), XP002147663 * |
Also Published As
Publication number | Publication date |
---|---|
JP2001506624A (en) | 2001-05-22 |
WO1998023269A1 (en) | 1998-06-04 |
CA2272275A1 (en) | 1998-06-04 |
EP1007035A1 (en) | 2000-06-14 |
AU1564797A (en) | 1998-06-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990618 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20001006 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): DE FR GB IT |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20001215 |