EP0967878A4 - Targeted cytotoxic cells - Google Patents
Targeted cytotoxic cellsInfo
- Publication number
- EP0967878A4 EP0967878A4 EP97947273A EP97947273A EP0967878A4 EP 0967878 A4 EP0967878 A4 EP 0967878A4 EP 97947273 A EP97947273 A EP 97947273A EP 97947273 A EP97947273 A EP 97947273A EP 0967878 A4 EP0967878 A4 EP 0967878A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cytotoxic cells
- targeted cytotoxic
- targeted
- cells
- cytotoxic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US740003 | 1991-08-02 | ||
US74000396A | 1996-10-23 | 1996-10-23 | |
PCT/US1997/019206 WO1998017116A1 (en) | 1996-10-23 | 1997-10-23 | Targeted cytotoxic cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0967878A1 EP0967878A1 (en) | 2000-01-05 |
EP0967878A4 true EP0967878A4 (en) | 2002-11-27 |
Family
ID=24974660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97947273A Withdrawn EP0967878A4 (en) | 1996-10-23 | 1997-10-23 | Targeted cytotoxic cells |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0967878A4 (en) |
JP (1) | JP2001503978A (en) |
CN (1) | CN1244772A (en) |
AU (1) | AU738749B2 (en) |
CA (1) | CA2269507A1 (en) |
IL (1) | IL129474A0 (en) |
WO (1) | WO1998017116A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7101542B1 (en) | 1999-05-26 | 2006-09-05 | Vallera Daniel A | Cell-mediated targeting of toxins to pathogenic cells |
PL366000A1 (en) * | 2000-08-08 | 2005-01-24 | M.G.V.S.Ltd. | Nucleic acid constructs, vascular cells transformed therewith, pharmaceutical compositions and methods utilizing same for inducing angiogenesis |
TW202115245A (en) * | 2019-06-27 | 2021-04-16 | 丹麥商諾佛 儂迪克股份有限公司 | Safe immuno-stealth cells |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995022618A1 (en) * | 1994-02-22 | 1995-08-24 | Dana-Farber Cancer Institute | Nucleic acid delivery system, method of synthesis and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69027210T2 (en) * | 1989-04-21 | 1997-01-23 | Protein Design Labs, Inc., Palo Alto, Calif. | RECOMBINANT ANTIBODY TOXIN FUSION PROTEIN |
-
1997
- 1997-10-23 WO PCT/US1997/019206 patent/WO1998017116A1/en not_active Application Discontinuation
- 1997-10-23 IL IL12947497A patent/IL129474A0/en unknown
- 1997-10-23 JP JP51964798A patent/JP2001503978A/en active Pending
- 1997-10-23 CN CN97199067A patent/CN1244772A/en active Pending
- 1997-10-23 CA CA002269507A patent/CA2269507A1/en not_active Abandoned
- 1997-10-23 EP EP97947273A patent/EP0967878A4/en not_active Withdrawn
- 1997-10-23 AU AU52394/98A patent/AU738749B2/en not_active Ceased
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995022618A1 (en) * | 1994-02-22 | 1995-08-24 | Dana-Farber Cancer Institute | Nucleic acid delivery system, method of synthesis and uses thereof |
Non-Patent Citations (6)
Title |
---|
CHEN S Y ET AL: "Potent antitumour activity of a new class of tumour-specific killer cells.", NATURE. ENGLAND 2 JAN 1997, vol. 385, no. 6611, 2 January 1997 (1997-01-02), pages 78 - 80, XP001093757, ISSN: 0028-0836 * |
CHEN S-Y ET AL: "DESIGN OF A GENETIC IMMUNOTOXIN TO ELIMINATE TOXIN IMMUNOGENICITY", GENE THERAPY, MACMILLAN PRESS LTD., BASINGSTOKE, GB, vol. 2, no. 2, 1 March 1995 (1995-03-01), pages 116 - 123, XP000672862, ISSN: 0969-7128 * |
HEIMBROOK D C ET AL: "TRANSFORMING GROWTH FACTOR ALPHA PSEUDOMONAS EXOTOXIN FUSION PROTEIN PROLONGS SURVIVAL OF NUDE MICE BEARING TUMOR XENOGRAFTS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 87, no. 12, 1990, 1990, pages 4697 - 4701, XP002215111, ISSN: 0027-8424 * |
See also references of WO9817116A1 * |
VITETTA E S ET AL: "Immunotoxins: magic bullets or misguided missiles ?", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 14, no. 6, June 1993 (1993-06-01), pages 252 - 259, XP002130421, ISSN: 0167-5699 * |
YANG A G ET AL: "A new class of antigen-specific killer cells.", NATURE BIOTECHNOLOGY. UNITED STATES JAN 1997, vol. 15, no. 1, January 1997 (1997-01-01), pages 46 - 51, XP001093758, ISSN: 1087-0156 * |
Also Published As
Publication number | Publication date |
---|---|
EP0967878A1 (en) | 2000-01-05 |
AU5239498A (en) | 1998-05-15 |
AU738749B2 (en) | 2001-09-27 |
CA2269507A1 (en) | 1998-04-30 |
JP2001503978A (en) | 2001-03-27 |
WO1998017116A1 (en) | 1998-04-30 |
IL129474A0 (en) | 2000-02-29 |
CN1244772A (en) | 2000-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990514 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021011 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20030424 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20031105 |