EP0964683A4 - Leukotriene antagonists for oral squamous cell carcinoma - Google Patents

Leukotriene antagonists for oral squamous cell carcinoma

Info

Publication number
EP0964683A4
EP0964683A4 EP97949709A EP97949709A EP0964683A4 EP 0964683 A4 EP0964683 A4 EP 0964683A4 EP 97949709 A EP97949709 A EP 97949709A EP 97949709 A EP97949709 A EP 97949709A EP 0964683 A4 EP0964683 A4 EP 0964683A4
Authority
EP
European Patent Office
Prior art keywords
cell carcinoma
squamous cell
oral squamous
leukotriene antagonists
leukotriene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97949709A
Other languages
German (de)
French (fr)
Other versions
EP0964683A1 (en
Inventor
Jerome H Fleisch
William T Jackson
Jason S Sawyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP0964683A1 publication Critical patent/EP0964683A1/en
Publication of EP0964683A4 publication Critical patent/EP0964683A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP97949709A 1996-12-13 1997-12-02 Leukotriene antagonists for oral squamous cell carcinoma Withdrawn EP0964683A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3426996P 1996-12-13 1996-12-13
US34269P 1996-12-13
US4087497P 1997-03-21 1997-03-21
US40874P 1997-03-21
PCT/US1997/021953 WO1998025615A1 (en) 1996-12-13 1997-12-02 Leukotriene antagonists for oral squamous cell carcinoma

Publications (2)

Publication Number Publication Date
EP0964683A1 EP0964683A1 (en) 1999-12-22
EP0964683A4 true EP0964683A4 (en) 2002-08-14

Family

ID=26710754

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97949709A Withdrawn EP0964683A4 (en) 1996-12-13 1997-12-02 Leukotriene antagonists for oral squamous cell carcinoma

Country Status (14)

Country Link
EP (1) EP0964683A4 (en)
JP (1) JP2001509142A (en)
KR (1) KR20000069452A (en)
CN (1) CN1245429A (en)
AU (1) AU726215B2 (en)
CA (1) CA2274855A1 (en)
EA (1) EA002742B1 (en)
IL (1) IL130304A0 (en)
NO (1) NO992846D0 (en)
NZ (1) NZ335922A (en)
PL (1) PL334241A1 (en)
TR (1) TR199901307T2 (en)
UA (1) UA47505C2 (en)
WO (1) WO1998025615A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001282717A1 (en) 2000-07-28 2002-02-13 Cancer Research Technology Limited Cancer treatment by combination therapy
GB0121285D0 (en) 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
GB2386836B (en) 2002-03-22 2006-07-26 Cancer Res Ventures Ltd Anti-cancer combinations
GB2394658A (en) 2002-11-01 2004-05-05 Cancer Rec Tech Ltd Oral anti-cancer composition
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
KR101898879B1 (en) 2014-03-05 2018-09-14 재단법인 진안홍삼연구소 A composition comprising the red ginseng extract of postmanufacture for treating or preventing oral squamous cell carcinoma

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260655A2 (en) * 1986-09-16 1988-03-23 Sumitomo Pharmaceuticals Company, Limited Unsaturated fatty acid derivatives and their production
EP0544488A2 (en) * 1991-11-25 1993-06-02 Eli Lilly And Company Substituted phenyl phenol leukotriene antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260655A2 (en) * 1986-09-16 1988-03-23 Sumitomo Pharmaceuticals Company, Limited Unsaturated fatty acid derivatives and their production
EP0544488A2 (en) * 1991-11-25 1993-06-02 Eli Lilly And Company Substituted phenyl phenol leukotriene antagonists

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9825615A1 *

Also Published As

Publication number Publication date
PL334241A1 (en) 2000-02-14
AU7845198A (en) 1998-07-03
EP0964683A1 (en) 1999-12-22
JP2001509142A (en) 2001-07-10
KR20000069452A (en) 2000-11-25
UA47505C2 (en) 2002-07-15
NO992846L (en) 1999-06-11
CA2274855A1 (en) 1998-06-18
WO1998025615A1 (en) 1998-06-18
TR199901307T2 (en) 1999-08-23
CN1245429A (en) 2000-02-23
IL130304A0 (en) 2000-06-01
NO992846D0 (en) 1999-06-11
NZ335922A (en) 2000-12-22
EA002742B1 (en) 2002-08-29
EA199900543A1 (en) 2000-02-28
AU726215B2 (en) 2000-11-02

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