EP0944394A4 - Traitement de l'infection a vih par action sur le recepteur de la cyclophiline de cellules hotes - Google Patents
Traitement de l'infection a vih par action sur le recepteur de la cyclophiline de cellules hotesInfo
- Publication number
- EP0944394A4 EP0944394A4 EP97917517A EP97917517A EP0944394A4 EP 0944394 A4 EP0944394 A4 EP 0944394A4 EP 97917517 A EP97917517 A EP 97917517A EP 97917517 A EP97917517 A EP 97917517A EP 0944394 A4 EP0944394 A4 EP 0944394A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hiv
- interfering
- infection
- treatment
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/52—Isomerases (5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1318596P | 1996-03-12 | 1996-03-12 | |
US613185P | 1996-03-12 | ||
US08/615,933 US5840305A (en) | 1996-03-14 | 1996-03-14 | Treatment of HIV-Infection by interfering with host cell cyclophilin receptor activity |
US615933 | 1996-03-14 | ||
PCT/US1997/003819 WO1997033604A1 (fr) | 1996-03-12 | 1997-03-12 | Traitement de l'infection a vih par action sur le recepteur de la cyclophiline de cellules hotes |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0944394A1 EP0944394A1 (fr) | 1999-09-29 |
EP0944394A4 true EP0944394A4 (fr) | 2003-05-14 |
Family
ID=26684543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97917517A Withdrawn EP0944394A4 (fr) | 1996-03-12 | 1997-03-12 | Traitement de l'infection a vih par action sur le recepteur de la cyclophiline de cellules hotes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0944394A4 (fr) |
JP (1) | JP2000510097A (fr) |
AU (1) | AU723905B2 (fr) |
CA (1) | CA2248192A1 (fr) |
WO (1) | WO1997033604A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2461740C (fr) | 2001-10-19 | 2013-02-12 | Isotechnika Inc. | Synthese d'analogues de cyclosporine |
AU2002347102A1 (en) * | 2001-10-25 | 2003-05-12 | Hans Will | Means for inhibition of the synthesis of viral proteins |
US7108988B2 (en) | 2001-11-02 | 2006-09-19 | The J. David Gladstone Institutes | Methods of identifying agents for inhibiting lentivirus replication |
WO2016054354A1 (fr) * | 2014-10-02 | 2016-04-07 | Dana-Farber Cancer Institute, Inc. | Compositions et méthodes pour le traitement de tumeurs malignes |
CN112888452A (zh) * | 2018-08-22 | 2021-06-01 | 贝凯恩生物医疗技术有限公司 | 环孢菌素组合物及使用方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0484281A2 (fr) * | 1990-11-02 | 1992-05-06 | Sandoz Ltd. | Cyclosporines |
WO1993023081A1 (fr) * | 1992-05-15 | 1993-11-25 | The Rockefeller University | Procedes et agents pour moduler la reponse immunitaire, et leurs utilisations |
WO1995007468A1 (fr) * | 1993-09-08 | 1995-03-16 | Sandoz Ltd. | Coffret de dosage |
-
1997
- 1997-03-12 WO PCT/US1997/003819 patent/WO1997033604A1/fr not_active Application Discontinuation
- 1997-03-12 AU AU25811/97A patent/AU723905B2/en not_active Ceased
- 1997-03-12 CA CA002248192A patent/CA2248192A1/fr not_active Abandoned
- 1997-03-12 EP EP97917517A patent/EP0944394A4/fr not_active Withdrawn
- 1997-03-12 JP JP09532773A patent/JP2000510097A/ja not_active Ceased
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0484281A2 (fr) * | 1990-11-02 | 1992-05-06 | Sandoz Ltd. | Cyclosporines |
WO1993023081A1 (fr) * | 1992-05-15 | 1993-11-25 | The Rockefeller University | Procedes et agents pour moduler la reponse immunitaire, et leurs utilisations |
WO1995007468A1 (fr) * | 1993-09-08 | 1995-03-16 | Sandoz Ltd. | Coffret de dosage |
Non-Patent Citations (4)
Title |
---|
ALLAIN F ET AL: "Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 178, no. 1, 13 January 1995 (1995-01-13), pages 113 - 120, XP004021130, ISSN: 0022-1759 * |
BILLICH A ET AL: "MODE OF ACTION OF SDZ NIM 811, A NONIMMUNOSUPPRESSIVE CYCLOSPORIN A ANALOG WITH ACTIVITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 1: INTERFERENCE WITH HIV PROTEIN-CYCLOPHILIN A INTERACTIONS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 69, no. 4, 1 April 1995 (1995-04-01), pages 2451 - 2461, XP002022423, ISSN: 0022-538X * |
ROYDON PRICE E ET AL: "CYCLOPHILIN B TRAFFICKING THROUGH THE SECRETORY PATHWAY IS ALTERED BY BINDING OF CYCLOSPORIN A", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, April 1994 (1994-04-01), pages 3931 - 3935, XP002931337, ISSN: 0027-8424 * |
See also references of WO9733604A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU723905B2 (en) | 2000-09-07 |
JP2000510097A (ja) | 2000-08-08 |
EP0944394A1 (fr) | 1999-09-29 |
CA2248192A1 (fr) | 1997-09-18 |
WO1997033604A1 (fr) | 1997-09-18 |
AU2581197A (en) | 1997-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19981012 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030402 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 39:00 K Ipc: 7A 61K 39/39 K Ipc: 7A 61K 38:13 J Ipc: 7A 61K 47/48 J Ipc: 7A 61K 47/48 B Ipc: 7C 12N 9/90 B Ipc: 7A 61K 39/39 B Ipc: 7A 61K 39/395 B Ipc: 7A 61K 38/13 A |
|
17Q | First examination report despatched |
Effective date: 20031023 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20050719 |