EP0907318A4 - Antioxidant compound - Google Patents

Antioxidant compound

Info

Publication number
EP0907318A4
EP0907318A4 EP97922494A EP97922494A EP0907318A4 EP 0907318 A4 EP0907318 A4 EP 0907318A4 EP 97922494 A EP97922494 A EP 97922494A EP 97922494 A EP97922494 A EP 97922494A EP 0907318 A4 EP0907318 A4 EP 0907318A4
Authority
EP
European Patent Office
Prior art keywords
antioxidant compound
antioxidant
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97922494A
Other languages
German (de)
French (fr)
Other versions
EP0907318A1 (en
Inventor
Giora Z Feuerstein
Paul G Lysko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0907318A1 publication Critical patent/EP0907318A1/en
Publication of EP0907318A4 publication Critical patent/EP0907318A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP97922494A 1996-04-29 1997-04-25 Antioxidant compound Withdrawn EP0907318A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1647696P 1996-04-29 1996-04-29
US16476P 1996-04-29
PCT/US1997/007037 WO1997040680A1 (en) 1996-04-29 1997-04-25 Antioxidant compound

Publications (2)

Publication Number Publication Date
EP0907318A1 EP0907318A1 (en) 1999-04-14
EP0907318A4 true EP0907318A4 (en) 2000-02-02

Family

ID=21777334

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97922494A Withdrawn EP0907318A4 (en) 1996-04-29 1997-04-25 Antioxidant compound

Country Status (3)

Country Link
EP (1) EP0907318A4 (en)
JP (1) JP2000510110A (en)
WO (1) WO1997040680A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
WO1994012178A1 (en) * 1992-12-01 1994-06-09 Smithkline Beecham Corporation Antioxidant neuroprotective use of, and method of treatment using, hydroxycarbazole compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5405863A (en) * 1992-12-01 1995-04-11 Smithkline Beecham Corporation Antioxidant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
WO1994012178A1 (en) * 1992-12-01 1994-06-09 Smithkline Beecham Corporation Antioxidant neuroprotective use of, and method of treatment using, hydroxycarbazole compounds

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRISTOW, O'CONNELL, GILBERT: "dose-response of chronic beta-blocker treatment in heart failure...", CIRCULATION, no. 89, 1994, pages 1632 - 1642, XP000863212 *
G Z FEUERSTEIN ET AL: "Carvedilol Update III. Rationale for use in congestive heart failure", DRUGS OF TODAY / MEDICAMENTOS DE ACTUALIDAD,ES,J.R. PROUS SS.A. INTERNATIONAL PUBLISHERS, vol. 31, no. SUPPL. F, pages 1-23, XP002039368, ISSN: 0025-7656 *
GILBERT E M, ANDERSON J L: "long term beta blocker vasodilator therapy improved cardiac functioning in idiopathic", AMER J MED, vol. 88, 1990, pages 223 - 229, XP000862858 *
See also references of WO9740680A1 *
WOODLEY,GILBERT,ANDERSON: "beta-blockade with bucindolol in heart failure caused by ischemic versus...", CIRCULATION, no. 84, 1991, pages 2426 - 2441, XP000863213 *

Also Published As

Publication number Publication date
EP0907318A1 (en) 1999-04-14
JP2000510110A (en) 2000-08-08
WO1997040680A1 (en) 1997-11-06

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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