EP0906330A4 - STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE - Google Patents

STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE

Info

Publication number
EP0906330A4
EP0906330A4 EP97918744A EP97918744A EP0906330A4 EP 0906330 A4 EP0906330 A4 EP 0906330A4 EP 97918744 A EP97918744 A EP 97918744A EP 97918744 A EP97918744 A EP 97918744A EP 0906330 A4 EP0906330 A4 EP 0906330A4
Authority
EP
European Patent Office
Prior art keywords
streptococcus pneumoniae
trna synthetase
isoleucyl trna
isoleucyl
synthetase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97918744A
Other languages
German (de)
French (fr)
Other versions
EP0906330A1 (en
Inventor
Elizabeth Jane Lawlor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Ltd
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, SmithKline Beecham Corp filed Critical SmithKline Beecham Ltd
Publication of EP0906330A1 publication Critical patent/EP0906330A1/en
Publication of EP0906330A4 publication Critical patent/EP0906330A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP97918744A 1996-04-18 1997-04-18 STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE Withdrawn EP0906330A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9608000.7A GB9608000D0 (en) 1996-04-18 1996-04-18 Novel compounds
GB9608000 1996-04-18
PCT/US1997/006551 WO1997039011A1 (en) 1996-04-18 1997-04-18 STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE

Publications (2)

Publication Number Publication Date
EP0906330A1 EP0906330A1 (en) 1999-04-07
EP0906330A4 true EP0906330A4 (en) 1999-10-20

Family

ID=10792244

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97918744A Withdrawn EP0906330A4 (en) 1996-04-18 1997-04-18 STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE

Country Status (4)

Country Link
EP (1) EP0906330A4 (en)
JP (1) JP2000509260A (en)
GB (1) GB9608000D0 (en)
WO (1) WO1997039011A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329168B1 (en) 1996-04-18 2001-12-11 Smithkline Beecham Corp. Streptococcus pneumoniae isoleucyl tRNA synthetase
EP0909819A1 (en) * 1997-10-17 1999-04-21 Smithkline Beecham Corporation Streptococcus pneumoniae Isoleucyl tRNA synthetase (Iles)[6.1.1.5.]
WO1999027129A1 (en) 1997-11-25 1999-06-03 The General Hospital Corporation Virulence-associated nucleic acid sequences and uses thereof
US7112716B2 (en) 2000-04-06 2006-09-26 The General Hospital Corporation Methods for screening and identifying host pathogen defense genes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028139A1 (en) * 1993-05-28 1994-12-08 Massachusetts Institute Of Technology tRNA BINDING-DEPENDENT INHIBITION OF MICROBIAL PATHOGEN GROWTH
WO1995009927A2 (en) * 1993-10-06 1995-04-13 Zeneca Limited Assay procedure and application in identification of herbicides
EP0786519A2 (en) * 1996-01-05 1997-07-30 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
WO1998019689A1 (en) * 1996-11-01 1998-05-14 Smithkline Beecham Corporation Novel coding sequences

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028139A1 (en) * 1993-05-28 1994-12-08 Massachusetts Institute Of Technology tRNA BINDING-DEPENDENT INHIBITION OF MICROBIAL PATHOGEN GROWTH
WO1995009927A2 (en) * 1993-10-06 1995-04-13 Zeneca Limited Assay procedure and application in identification of herbicides
EP0786519A2 (en) * 1996-01-05 1997-07-30 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
WO1998019689A1 (en) * 1996-11-01 1998-05-14 Smithkline Beecham Corporation Novel coding sequences

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BUDAVARI ET AL.: "The Merck Index, 12th ed.", 1996, MERCK & CO., INC., WHITEHOUSE STATION, NJ, XP002113499 *
HONG ET AL.: "An isoleucyl-tRNA synthetase gene from Campylobacter jejuni", MICROBIOLOGY, vol. 141, no. 10, October 1995 (1995-10-01), pages 2561 - 2567, XP002112692 *
LASKE ET AL.: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part I. The antibacterial effect", ARCHIV DER PHARMAZIE, vol. 322, no. 12, December 1989 (1989-12-01), pages 847 - 852, XP002113352 *
LASKE ET AL: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part II. The antileukemic effect", ARCHIV DER PHARMAZIE, vol. 322, no. 12, December 1989 (1989-12-01), pages 857 - 862, XP002106398, ISSN: 0365-6233 *
See also references of WO9739011A1 *

Also Published As

Publication number Publication date
JP2000509260A (en) 2000-07-25
GB9608000D0 (en) 1996-06-19
EP0906330A1 (en) 1999-04-07
WO1997039011A1 (en) 1997-10-23

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Legal Events

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