EP0904538A4 - Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies - Google Patents

Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Info

Publication number
EP0904538A4
EP0904538A4 EP96944237A EP96944237A EP0904538A4 EP 0904538 A4 EP0904538 A4 EP 0904538A4 EP 96944237 A EP96944237 A EP 96944237A EP 96944237 A EP96944237 A EP 96944237A EP 0904538 A4 EP0904538 A4 EP 0904538A4
Authority
EP
European Patent Office
Prior art keywords
atherosclerosis
diagnosis
treatment
cholesterol antibodies
cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP96944237A
Other languages
German (de)
French (fr)
Other versions
EP0904538A1 (en
Inventor
Jan Dijkstra
Glenn M Swartz Jr
Jacinta Aniagolu
Carol A Nacy
Shawn J Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Casi Pharmaceuticals Inc
Original Assignee
Entremed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entremed Inc filed Critical Entremed Inc
Publication of EP0904538A1 publication Critical patent/EP0904538A1/en
Publication of EP0904538A4 publication Critical patent/EP0904538A4/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
EP96944237A 1995-12-05 1996-12-05 Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies Ceased EP0904538A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US759569 1985-07-26
US820395P 1995-12-05 1995-12-05
US8203P 1995-12-05
US75956996A 1996-12-04 1996-12-04
PCT/US1996/019381 WO1997021099A1 (en) 1995-12-05 1996-12-05 Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Publications (2)

Publication Number Publication Date
EP0904538A1 EP0904538A1 (en) 1999-03-31
EP0904538A4 true EP0904538A4 (en) 2001-04-11

Family

ID=26677928

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96944237A Ceased EP0904538A4 (en) 1995-12-05 1996-12-05 Method of diagnosis and treatment of atherosclerosis using anti-cholesterol antibodies

Country Status (5)

Country Link
EP (1) EP0904538A4 (en)
JP (1) JP2002504225A (en)
AU (1) AU713531B2 (en)
CA (1) CA2239092A1 (en)
WO (1) WO1997021099A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492185B1 (en) * 1998-01-16 2002-12-10 Abbott Laboratories Immunoassay for detection of very low density lipoprotein and antibodies useful therefor
AUPR458201A0 (en) 2001-04-23 2001-05-24 Commonwealth Scientific And Industrial Research Organisation Fluid properties evaluation
WO2005023830A2 (en) * 2003-09-05 2005-03-17 The Scripps Research Institute Ozonation products of cholesterol for the treatment and prevention of atherosclerosis and/or cardiovascular diseases
US20050085556A1 (en) * 2003-09-05 2005-04-21 Paul Wentworth Detection of cholesterol ozonation products
CA2465427A1 (en) * 2004-04-28 2005-10-28 Imi International Medical Innovations Inc. Direct assay of cholesterol in skin samples removed by tape stripping

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018067A1 (en) * 1992-03-06 1993-09-16 Abbott Laboratories Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
WO1994023302A1 (en) * 1993-04-07 1994-10-13 The Australian National University Immunological assay of oxidatively modified human low density lipoproteins in plasma
EP0621284A1 (en) * 1992-08-14 1994-10-26 Shino-Test Corporation PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018067A1 (en) * 1992-03-06 1993-09-16 Abbott Laboratories Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
EP0621284A1 (en) * 1992-08-14 1994-10-26 Shino-Test Corporation PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES
WO1994023302A1 (en) * 1993-04-07 1994-10-13 The Australian National University Immunological assay of oxidatively modified human low density lipoproteins in plasma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9721099A1 *
SWARTZ GM ET AL: "Antibodies to cholesterol", PROC. NATL. ACAD. SCI., vol. 85, March 1988 (1988-03-01), USA, pages 1902 - 1906, XP000942042 *

Also Published As

Publication number Publication date
CA2239092A1 (en) 1997-06-12
AU1409797A (en) 1997-06-27
EP0904538A1 (en) 1999-03-31
WO1997021099A1 (en) 1997-06-12
AU713531B2 (en) 1999-12-02
JP2002504225A (en) 2002-02-05

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