EP0879297A4 - Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern - Google Patents
Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parameternInfo
- Publication number
- EP0879297A4 EP0879297A4 EP96945612A EP96945612A EP0879297A4 EP 0879297 A4 EP0879297 A4 EP 0879297A4 EP 96945612 A EP96945612 A EP 96945612A EP 96945612 A EP96945612 A EP 96945612A EP 0879297 A4 EP0879297 A4 EP 0879297A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- conducting
- situ hybridization
- multiparametric fluorescence
- multiparametric
- fluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57762295A | 1995-12-22 | 1995-12-22 | |
US577622 | 1995-12-22 | ||
US58071795A | 1995-12-29 | 1995-12-29 | |
US580717 | 1995-12-29 | ||
US08/640,658 US5792610A (en) | 1996-05-01 | 1996-05-01 | Method for conducting multiparametric fluorescence in situ hybridization |
US640658 | 1996-05-01 | ||
PCT/US1996/020085 WO1997023649A1 (en) | 1995-12-22 | 1996-12-20 | Method and apparatus for conducting multiparametric fluorescence in situ hybridization |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0879297A1 EP0879297A1 (de) | 1998-11-25 |
EP0879297A4 true EP0879297A4 (de) | 2003-04-16 |
Family
ID=27416276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96945612A Withdrawn EP0879297A4 (de) | 1995-12-22 | 1996-12-20 | Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0879297A4 (de) |
JP (1) | JPH11510707A (de) |
CA (1) | CA2241364A1 (de) |
WO (1) | WO1997023649A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834203A (en) * | 1997-08-25 | 1998-11-10 | Applied Spectral Imaging | Method for classification of pixels into groups according to their spectra using a plurality of wide band filters and hardwire therefore |
GB9807257D0 (en) | 1998-04-03 | 1998-06-03 | Nat Food Research Inst Ministr | Apparatus and methods for fourier spectral analysis in a scanning spot microscope |
US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
CA2328609A1 (en) | 1998-05-16 | 1999-11-25 | Pe Corporation (Ny) | Instrument for monitoring polymerase chain reaction of dna |
US6818437B1 (en) | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
AU758466B2 (en) * | 1998-06-02 | 2003-03-20 | Yale University | Multiparametric fluorescence in situ hybridization |
US6174681B1 (en) * | 1999-03-05 | 2001-01-16 | Mayo Foundation For Medical Education And Research | Method and probe set for detecting cancer |
US7410793B2 (en) | 1999-05-17 | 2008-08-12 | Applera Corporation | Optical instrument including excitation source |
US20050279949A1 (en) | 1999-05-17 | 2005-12-22 | Applera Corporation | Temperature control for light-emitting diode stabilization |
US7423750B2 (en) | 2001-11-29 | 2008-09-09 | Applera Corporation | Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion |
AU2003245302A1 (en) | 2002-05-17 | 2003-12-02 | Applera Corporation | Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength |
US11149299B2 (en) * | 2015-06-25 | 2021-10-19 | Ramesh Vallabhaneni | Method and system for multiplex profiling of chromosomes in biological samples using target-specific DNA probes |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4905169A (en) * | 1988-06-02 | 1990-02-27 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for simultaneously measuring a plurality of spectral wavelengths present in electromagnetic radiation |
WO1997040191A1 (en) * | 1996-04-22 | 1997-10-30 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization |
US5936731A (en) * | 1991-02-22 | 1999-08-10 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting |
FR2784683A1 (fr) * | 1998-10-15 | 2000-04-21 | Genset Sa | Sondes fluorescentes de peinture chromosomique |
-
1996
- 1996-12-20 WO PCT/US1996/020085 patent/WO1997023649A1/en not_active Application Discontinuation
- 1996-12-20 JP JP9523765A patent/JPH11510707A/ja active Pending
- 1996-12-20 EP EP96945612A patent/EP0879297A4/de not_active Withdrawn
- 1996-12-20 CA CA 2241364 patent/CA2241364A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4905169A (en) * | 1988-06-02 | 1990-02-27 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for simultaneously measuring a plurality of spectral wavelengths present in electromagnetic radiation |
US5936731A (en) * | 1991-02-22 | 1999-08-10 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting |
WO1997040191A1 (en) * | 1996-04-22 | 1997-10-30 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization |
FR2784683A1 (fr) * | 1998-10-15 | 2000-04-21 | Genset Sa | Sondes fluorescentes de peinture chromosomique |
Non-Patent Citations (12)
Title |
---|
DAUWERSE ET AL: "Multiple colors by FISH using ratio labelled DNA probes create a molecular karyotype", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 1, no. 8, 1992, pages 593 - 598, XP002161585, ISSN: 0964-6906 * |
GARINI Y ET AL: "Spectral Karyotyping", BIOIMAGING, IOP PUBLISHING, GB, vol. 4, no. 2, June 1996 (1996-06-01), pages 65 - 72, XP002110740, ISSN: 0964-1726 * |
KLINGER K W ET AL: "MAPPING BY FIVE COLOR FLUORESCENCE IN-SITU HYBRIDIZATION", CYTOGENETICS AND CELL GENETICS, vol. 58, no. 1-4, 1991, pages 2149, XP009005163, ISSN: 0301-0171 * |
LENGAUER C ET AL: "CHROMOSOMAL BAR CODES PRODUCED BY MULTICOLOR FLUORESCENCE IN SITU HYBRIDIZATION WITH MULTIPLE YAC CLONES AND WHOLE CHROMOSOME PAINTING PROBES", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 2, no. 5, 1 May 1993 (1993-05-01), pages 505 - 512, XP000612071, ISSN: 0964-6906 * |
MALIK Z ET AL: "Fourier transform multipixel spectroscopy for quantitative cytology.", JOURNAL OF MICROSCOPY (OXFORD), vol. 182, no. 2, 1996, pages 133 - 140, XP009005240, ISSN: 0022-2720 * |
MARX J: "NEW METHODS FOR EXPANDING THE CHROMOSOMAL PAINT KIT", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 273, 26 July 1996 (1996-07-26), pages 430, XP000952835, ISSN: 0036-8075 * |
NEDERLOF P M ET AL: "MULTIPLE FLUORESCENCE IN SITU HYBRIDIZATION", CYTOMETRY, ALAN LISS, NEW YORK, US, vol. 11, 1990, pages 126 - 131, XP000960811, ISSN: 0196-4763 * |
RIED T ET AL: "SIMULTANEOUS VISUALIZATION OF SEVEN DIFFERENT DNA PROBES BY IN SITU HYBRIDIZATION USING COMBINATORIAL FLUORESCENCE AND DIGITAL IMAGING MICROSCOPY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 89, 1 February 1992 (1992-02-01), pages 1388 - 1392, XP002073155, ISSN: 0027-8424 * |
SCHROECK E ET AL: "Spectral karyotyping (SKY) of human chromosomes.", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 59, no. 4 SUPPL., 1996, 46th Annual Meeting of the American Society of Human Genetics;San Francisco, California, USA; October 29-November 2, 1996, pages A50, XP009005146, ISSN: 0002-9297 * |
See also references of WO9723649A1 * |
TOCHAROENTANAPHOL C ET AL: "Multicolor fluorescence in situ hybridization on metaphase chromosomes and interphase Halo-preparations using cosmid and YAC clones for the simultaneous high resolution mapping of deletions in the dystrophin gene.", HUMAN GENETICS. GERMANY MAR 1994, vol. 93, no. 3, March 1994 (1994-03-01), pages 229 - 235, XP009005164, ISSN: 0340-6717 * |
VELDMAN TIM ET AL: "Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping.", NATURE GENETICS, vol. 15, no. 4, 1997, pages 406 - 410, XP009005148, ISSN: 1061-4036 * |
Also Published As
Publication number | Publication date |
---|---|
EP0879297A1 (de) | 1998-11-25 |
JPH11510707A (ja) | 1999-09-21 |
WO1997023649A1 (en) | 1997-07-03 |
CA2241364A1 (en) | 1997-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980721 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030228 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20030514 |