EP0879297A4 - Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern - Google Patents

Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern

Info

Publication number
EP0879297A4
EP0879297A4 EP96945612A EP96945612A EP0879297A4 EP 0879297 A4 EP0879297 A4 EP 0879297A4 EP 96945612 A EP96945612 A EP 96945612A EP 96945612 A EP96945612 A EP 96945612A EP 0879297 A4 EP0879297 A4 EP 0879297A4
Authority
EP
European Patent Office
Prior art keywords
conducting
situ hybridization
multiparametric fluorescence
multiparametric
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96945612A
Other languages
English (en)
French (fr)
Other versions
EP0879297A1 (de
Inventor
Franklin R Witney
David M Heffelfinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/640,658 external-priority patent/US5792610A/en
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of EP0879297A1 publication Critical patent/EP0879297A1/de
Publication of EP0879297A4 publication Critical patent/EP0879297A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP96945612A 1995-12-22 1996-12-20 Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern Withdrawn EP0879297A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US57762295A 1995-12-22 1995-12-22
US577622 1995-12-22
US58071795A 1995-12-29 1995-12-29
US580717 1995-12-29
US08/640,658 US5792610A (en) 1996-05-01 1996-05-01 Method for conducting multiparametric fluorescence in situ hybridization
US640658 1996-05-01
PCT/US1996/020085 WO1997023649A1 (en) 1995-12-22 1996-12-20 Method and apparatus for conducting multiparametric fluorescence in situ hybridization

Publications (2)

Publication Number Publication Date
EP0879297A1 EP0879297A1 (de) 1998-11-25
EP0879297A4 true EP0879297A4 (de) 2003-04-16

Family

ID=27416276

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96945612A Withdrawn EP0879297A4 (de) 1995-12-22 1996-12-20 Verfahren und gerät zur durchführung von fluoreszenz in situ hybridisierung unter messung einer vielzahl von parametern

Country Status (4)

Country Link
EP (1) EP0879297A4 (de)
JP (1) JPH11510707A (de)
CA (1) CA2241364A1 (de)
WO (1) WO1997023649A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834203A (en) * 1997-08-25 1998-11-10 Applied Spectral Imaging Method for classification of pixels into groups according to their spectra using a plurality of wide band filters and hardwire therefore
GB9807257D0 (en) 1998-04-03 1998-06-03 Nat Food Research Inst Ministr Apparatus and methods for fourier spectral analysis in a scanning spot microscope
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
CA2328609A1 (en) 1998-05-16 1999-11-25 Pe Corporation (Ny) Instrument for monitoring polymerase chain reaction of dna
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
AU758466B2 (en) * 1998-06-02 2003-03-20 Yale University Multiparametric fluorescence in situ hybridization
US6174681B1 (en) * 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
US7410793B2 (en) 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US20050279949A1 (en) 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
US7423750B2 (en) 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
AU2003245302A1 (en) 2002-05-17 2003-12-02 Applera Corporation Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
US11149299B2 (en) * 2015-06-25 2021-10-19 Ramesh Vallabhaneni Method and system for multiplex profiling of chromosomes in biological samples using target-specific DNA probes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4905169A (en) * 1988-06-02 1990-02-27 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for simultaneously measuring a plurality of spectral wavelengths present in electromagnetic radiation
WO1997040191A1 (en) * 1996-04-22 1997-10-30 Applied Spectral Imaging Ltd. Method for simultaneous detection of multiple fluorophores for in situ hybridization
US5936731A (en) * 1991-02-22 1999-08-10 Applied Spectral Imaging Ltd. Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting
FR2784683A1 (fr) * 1998-10-15 2000-04-21 Genset Sa Sondes fluorescentes de peinture chromosomique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4905169A (en) * 1988-06-02 1990-02-27 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for simultaneously measuring a plurality of spectral wavelengths present in electromagnetic radiation
US5936731A (en) * 1991-02-22 1999-08-10 Applied Spectral Imaging Ltd. Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting
WO1997040191A1 (en) * 1996-04-22 1997-10-30 Applied Spectral Imaging Ltd. Method for simultaneous detection of multiple fluorophores for in situ hybridization
FR2784683A1 (fr) * 1998-10-15 2000-04-21 Genset Sa Sondes fluorescentes de peinture chromosomique

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
DAUWERSE ET AL: "Multiple colors by FISH using ratio labelled DNA probes create a molecular karyotype", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 1, no. 8, 1992, pages 593 - 598, XP002161585, ISSN: 0964-6906 *
GARINI Y ET AL: "Spectral Karyotyping", BIOIMAGING, IOP PUBLISHING, GB, vol. 4, no. 2, June 1996 (1996-06-01), pages 65 - 72, XP002110740, ISSN: 0964-1726 *
KLINGER K W ET AL: "MAPPING BY FIVE COLOR FLUORESCENCE IN-SITU HYBRIDIZATION", CYTOGENETICS AND CELL GENETICS, vol. 58, no. 1-4, 1991, pages 2149, XP009005163, ISSN: 0301-0171 *
LENGAUER C ET AL: "CHROMOSOMAL BAR CODES PRODUCED BY MULTICOLOR FLUORESCENCE IN SITU HYBRIDIZATION WITH MULTIPLE YAC CLONES AND WHOLE CHROMOSOME PAINTING PROBES", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 2, no. 5, 1 May 1993 (1993-05-01), pages 505 - 512, XP000612071, ISSN: 0964-6906 *
MALIK Z ET AL: "Fourier transform multipixel spectroscopy for quantitative cytology.", JOURNAL OF MICROSCOPY (OXFORD), vol. 182, no. 2, 1996, pages 133 - 140, XP009005240, ISSN: 0022-2720 *
MARX J: "NEW METHODS FOR EXPANDING THE CHROMOSOMAL PAINT KIT", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 273, 26 July 1996 (1996-07-26), pages 430, XP000952835, ISSN: 0036-8075 *
NEDERLOF P M ET AL: "MULTIPLE FLUORESCENCE IN SITU HYBRIDIZATION", CYTOMETRY, ALAN LISS, NEW YORK, US, vol. 11, 1990, pages 126 - 131, XP000960811, ISSN: 0196-4763 *
RIED T ET AL: "SIMULTANEOUS VISUALIZATION OF SEVEN DIFFERENT DNA PROBES BY IN SITU HYBRIDIZATION USING COMBINATORIAL FLUORESCENCE AND DIGITAL IMAGING MICROSCOPY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 89, 1 February 1992 (1992-02-01), pages 1388 - 1392, XP002073155, ISSN: 0027-8424 *
SCHROECK E ET AL: "Spectral karyotyping (SKY) of human chromosomes.", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 59, no. 4 SUPPL., 1996, 46th Annual Meeting of the American Society of Human Genetics;San Francisco, California, USA; October 29-November 2, 1996, pages A50, XP009005146, ISSN: 0002-9297 *
See also references of WO9723649A1 *
TOCHAROENTANAPHOL C ET AL: "Multicolor fluorescence in situ hybridization on metaphase chromosomes and interphase Halo-preparations using cosmid and YAC clones for the simultaneous high resolution mapping of deletions in the dystrophin gene.", HUMAN GENETICS. GERMANY MAR 1994, vol. 93, no. 3, March 1994 (1994-03-01), pages 229 - 235, XP009005164, ISSN: 0340-6717 *
VELDMAN TIM ET AL: "Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping.", NATURE GENETICS, vol. 15, no. 4, 1997, pages 406 - 410, XP009005148, ISSN: 1061-4036 *

Also Published As

Publication number Publication date
EP0879297A1 (de) 1998-11-25
JPH11510707A (ja) 1999-09-21
WO1997023649A1 (en) 1997-07-03
CA2241364A1 (en) 1997-07-03

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Legal Events

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